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1 bA is required in the tetrahydrofolate (THF) biosynthesis pathway.
2 ich encodes an enzyme in the brassinosteroid biosynthesis pathway.
3 es in the auxin [indole-3-acetic acid (IAA)] biosynthesis pathway.
4 sferase TarM, a component of the WTA de novo biosynthesis pathway.
5 trols activation of genes in the anthocyanin biosynthesis pathway.
6 cificity and 2OST position in the ordered HS biosynthesis pathway.
7 espective fatty alcohols for the plasmalogen-biosynthesis pathway.
8 three genes encoding enzymes of the L-serine biosynthesis pathway.
9 irst time and provides a revised diphthamide biosynthesis pathway.
10 ture via incorporation into the phospholipid biosynthesis pathway.
11 osition and genes from triacylglycerol (TAG) biosynthesis pathway.
12 a previously unknown step in the diphthamide biosynthesis pathway.
13 irst enzyme in the branched-chain amino acid biosynthesis pathway.
14 ree genes encoding proteins in the menadione biosynthesis pathway.
15 arately function in biotin transport and the biosynthesis pathway.
16 as kauralexin production by the diterpenoid biosynthesis pathway.
17 been associated with defects in the melanin-biosynthesis pathway.
18 through PXR-mediated alteration of the heme biosynthesis pathway.
19 irst enzyme in the branched-chain amino acid biosynthesis pathway.
20 17 natural products from the acetylaranotin biosynthesis pathway.
21 nown genes in the phenylpropanoid-monolignol biosynthesis pathway.
22 ical bifurcated hydroxylation process in the biosynthesis pathway.
23 gulation of genes of the T4SS and riboflavin biosynthesis pathway.
24 this screen inactivated the menaquinone (MK) biosynthesis pathway.
25 nmobile precursor upstream of MAX1 in the SL biosynthesis pathway.
26 2, and MYB113 which regulate the anthocyanin biosynthesis pathway.
27 level of the environment regulates the BCAA biosynthesis pathway.
28 , the first committed step in the carotenoid biosynthesis pathway.
29 AF-12 ligands, closing a major gap in the DA biosynthesis pathway.
30 Escherichia coli genes, including the purine biosynthesis pathway.
31 ny of the known steps in the thyroid hormone biosynthesis pathway.
32 mon cellular pathway: the de novo pyrimidine biosynthesis pathway.
33 ies of enzymes involved in the mannose donor biosynthesis pathway.
34 ng of the 3-deoxy-d-manno-octulosonate (KDO) biosynthesis pathway.
35 g drug synergies in the mycobacterial folate biosynthesis pathway.
36 e product of DHODH in the de novo pyrimidine biosynthesis pathway.
37 n the absence of a de novo purine nucleotide biosynthesis pathway.
38 which is an enzyme in the de novo pyrimidine biosynthesis pathway.
39 HAS), the first committed enzyme in the BCAA biosynthesis pathway.
40 codes a key enzyme in the pyrimidine de novo biosynthesis pathway.
41 bition by cysteine, the final product of the biosynthesis pathway.
42 produced by DHDPA synthase within the lysine biosynthesis pathway.
43 ihydropterin (HMDHP) in the classical folate biosynthesis pathway.
44 acid cycle and its efflux to the fatty acid biosynthesis pathway.
45 droxylase and C(17,20)-lyase in the androgen biosynthesis pathway.
46 cts for many cell surface proteins along the biosynthesis pathway.
47 actor for down regulation of the cholesterol biosynthesis pathway.
48 YUCCA6 is involved in a Trp-dependent auxin biosynthesis pathway.
49 and subsequent disruption of the methionine biosynthesis pathway.
50 he 3-deoxy-D-manno-oct-2-ulosonic acid (Kdo) biosynthesis pathway.
51 e-glycine amidinotransferase in the creatine biosynthesis pathway.
52 nst diverse microbes carrying the riboflavin biosynthesis pathway.
53 rs to result from suppression of the de novo biosynthesis pathway.
54 specific transformations in the cholesterol biosynthesis pathway.
55 de novo coccolithovirus-encoded sphingolipid biosynthesis pathway.
56 ic for biotin in that it lacks a full biotin biosynthesis pathway.
57 ffects of small molecules on the cholesterol biosynthesis pathway.
58 also functions as a repressor for the biotin biosynthesis pathway.
59 mediates of the plastid-localized carotenoid biosynthesis pathway.
60 majority of enzymes forming the cholesterol biosynthesis pathway.
61 sential enzyme in the ergosterol/cholesterol biosynthesis pathway.
62 GP), a major control enzyme in the ascorbate biosynthesis pathway.
63 ng the antagonistic autophagy and methionine biosynthesis pathways.
64 s and affects the related glycine and serine biosynthesis pathways.
65 ocesses, including abnormal control of lipid biosynthesis pathways.
66 abolites were in the glutathione and glycine biosynthesis pathways.
67 ng carbon allocation between storage and the biosynthesis pathways.
68 one of four hypothesized Trp-dependent auxin biosynthesis pathways.
69 ntapped source for uncovering new metabolite biosynthesis pathways.
70 of the diatomic ligands relies on dedicated biosynthesis pathways.
71 omal peptides, and transferases from various biosynthesis pathways.
72 tions of one or more genes on the amino acid biosynthesis pathways.
74 tor activity, and the isoprenoid/cholesterol biosynthesis pathway additionally suggest a role of sEH
75 provide evidence for conservation of the ABA biosynthesis pathway among members of the plant kingdom.
76 lear localization of the de novo thymidylate biosynthesis pathway and a decrease in DNA strand breaks
77 some unigenes involved in the insect hormone biosynthesis pathway and also 747 lipids metabolism-rela
78 sociated with deficiencies of the GPI-anchor biosynthesis pathway and also serves to highlight the po
80 silencing of the enzymes involved in the HS biosynthesis pathway and by competition with modified he
81 modium falciparum possesses a functional GSH biosynthesis pathway and contains mM concentrations of t
82 results in an increased flux through the RA biosynthesis pathway and elevated RA levels despite the
83 seases caused by genetic defects in the heme biosynthesis pathway and exacerbated by controlled up-re
85 involved in the third step of the ubiquinone biosynthesis pathway and harbors a flavin mononucleotide
86 focus specifically on the lipopolysaccharide biosynthesis pathway and identify eight putative targets
87 roduct formation in a heterologous glucarate biosynthesis pathway and identify superior enzyme varian
88 ndicate decreases to the salicylic acid (SA) biosynthesis pathway and increases in the auxin [indole-
89 s the third enzyme in the de novo pyrimidine biosynthesis pathway and is a potential new antibacteria
90 the rate-limiting enzyme in the cholesterol biosynthesis pathway and is inhibited by statins, a clas
93 actor, we show that cells use the hexosamine biosynthesis pathway and O-linked beta-N-acetylglucosami
94 ene expression levels of the triacylglycerol biosynthesis pathway and oil composition over a time ser
97 tanding of NLS as a disorder of the L-serine biosynthesis pathway and suggest that NLS represents the
98 in genes encoding enzymes of the vitamin B12 biosynthesis pathway and the vitamin B12-dependent methy
99 ed for shade-induced modulation of the auxin biosynthesis pathway and thereby enhances cell elongatio
100 e dinucleotide (NAD) is produced via de novo biosynthesis pathways and by salvage or recycling routes
102 in vitro data on the signal transduction and biosynthesis pathways and in vivo data on the expression
103 ete de novo pyrimidine, purine, and thiamine biosynthesis pathways and is unique amongst studied stra
104 thetic strategy was inspired by the putative biosynthesis pathways and its development was facilitate
106 lated genes involved in reproductive hormone biosynthesis pathways and provide a framework for future
107 that dysregulation of the purine nucleotide biosynthesis pathways and the addition of exogenous puri
108 ctional genomic refinement of characteristic biosynthesis pathways and will help develop a more diver
109 PHGDH catalyses the first step in the serine biosynthesis pathway, and breast cancer cells with high
110 ucosamine, an intermediate of the hexosamine biosynthesis pathway, and involve PI3K-dependent O-GlcNA
111 mide-ribonucleotide (PRFAR) in the histidine biosynthesis pathway, and it is a paradigm for the study
112 nzoate, the intermediate in the enterobactin biosynthesis pathway, and providing 2,3-dihydroxybenzoat
113 synthase, the first enzyme of the carotenoid biosynthesis pathway, and therefore is unable to synthes
114 ing of three genes), a functional zeaxanthin biosynthesis pathway (approximately 11 kb DNA consisting
115 combined D-xylose utilization and zeaxanthin biosynthesis pathway (approximately 19 kb consisting of
116 Two of the latter steps in the morphine biosynthesis pathway are demethylation of thebaine at th
117 s associated with mutations in the trehalose biosynthesis pathway are not abolished by providing abun
118 lyses showed that only three genes in the SL biosynthesis pathways are expressed and transcribed diff
120 compartments, indicating that the JA and GLV biosynthesis pathways are physically separated in maize.
122 he initial steps of steroid and/or oxysterol biosynthesis pathways are present and active in adipocyt
124 NA replication pathway above the cholesterol biosynthesis pathway as a R273H mtp53 activated proteomi
127 progesterone), which belonged to the steroid biosynthesis pathway as significant metabolites upregula
128 s are thought to be implicated in the lignin biosynthesis pathway as storage and/or transportation fo
129 YCR2, which encodes an enzyme in the proline biosynthesis pathway, as the cause of a unique syndrome
134 ulate expression of genes in the anthocyanin biosynthesis pathway by inducing transcription factors (
135 Prolonged activation of both uptake and biosynthesis pathways by cotreatment with a liver X rece
136 es for the enzymes of the type II fatty acid biosynthesis pathway can now be exploited in the rationa
137 complementation with key enzymes from lipid biosynthesis pathways can partially rescue both vacuole
138 sphokinase (HPPK), an enzyme from the folate biosynthesis pathway, catalyzes the pyrophosphoryl trans
139 is an essential enzyme of proteoglycan (PG) biosynthesis pathway catalyzing the initial and rate-lim
141 ymes that constitute the de novo thymidylate biosynthesis pathway, cSHMT, thymidylate synthase, and d
142 lycosyltransferases involved in the O-glycan biosynthesis pathway, described here for the first time,
143 iple, four sets of two genes of the l-lysine biosynthesis pathway distantly located on the E. coli ch
144 ariants associated with genes in the glycine biosynthesis pathways do not provide consistent evidence
147 that strain 195 contains complete amino acid biosynthesis pathways, even though current genome annota
148 es and identified 55% with upregulated mtDNA biosynthesis pathway expression compared with normal hem
150 that glutaredoxin 3 requires the glutathione biosynthesis pathway for its function and can oxidize su
151 monstrated the presence of an intact de novo biosynthesis pathway for NAD(+) from tryptophan via QA,
155 tructure and describe recent advances in the biosynthesis pathway for type I LTA, d-alanylated polygl
156 ts small genome, low-GC content, and lack of biosynthesis pathways for most amino acids and vitamins.
157 , cyp71A13, and myb28myb29) disrupted in the biosynthesis pathways for these plant secondary metaboli
159 mRNA expression of serine/one-carbon/glycine biosynthesis pathway genes (Phgdh, Psat1 and Psph) and t
162 -EC) to glutathione (GSH) in the glutathione biosynthesis pathway, gsh2 mutants exhibited gamma-EC hy
164 oxy-D-manno- and GDP-6-deoxy-D-altro-heptose biosynthesis pathways has provided the foundation for el
165 d with downregulation of the phenylpropanoid biosynthesis pathway have been identified in several gra
168 f bioenergy crops and direct manipulation of biosynthesis pathways have produced lignin feedstocks wi
169 T, and AGPS, all involved in the plasmalogen-biosynthesis pathway, have been described in individuals
170 hway is directly regulated by the hexosamine biosynthesis pathway (HBP) in response to metabolic nutr
173 quiring biosynthetic pathway, the hexosamine biosynthesis pathway (HBP) via regulation of expression
174 pacts glycan biosynthesis through Hexosamine Biosynthesis Pathway (HBP), as well as cellular redox ho
176 the nicotinamide adenine dinucleotide (NAD) biosynthesis pathway implicated in protection against ax
177 ealed that downregulation of the cholesterol biosynthesis pathway improves neurological phenotypes in
178 ndings suggest that the presence of the 27HC biosynthesis pathway in adipocytes may represent a defen
179 sterase (CSE) as an enzyme in the monolignol biosynthesis pathway in Arabidopsis thaliana, although t
181 an additional component of the canonical SL biosynthesis pathway in Arabidopsis, we provide a new to
183 reusing the same genetic parts to express a biosynthesis pathway in both model and non-model hosts.
186 gulation of the genes involved in the lignin biosynthesis pathway in developing storage roots, leadin
187 y steps of the currently accepted monolignol biosynthesis pathway in dicots may have functionally red
188 d to the wholesale deployment of the cuticle biosynthesis pathway in early embryos of A. gambiae.
189 ize the 1-deoxy-D-xylulose-5-phosphate (DXP) biosynthesis pathway in Escherichia coli to overproduce
194 we found that disruption of the vitamin B(6) biosynthesis pathway in S. pneumoniae caused a significa
195 re, we expressed the core Arabidopsis starch-biosynthesis pathway in Saccharomyces cerevisiae purged
198 e dehydratase IlvA is part of the isoleucine biosynthesis pathway in the Gram-positive model bacteriu
199 Genes encoding key enzymes of the ectoine biosynthesis pathway in the halotolerant obligate methan
200 of the folate-dependent de novo thymidylate biosynthesis pathway in the nucleus accounts for the pre
201 more products of the mevalonate/cholesterol biosynthesis pathway in the progression of prostate canc
202 cci (VRE) is due to an alternative cell wall biosynthesis pathway in which d-Ala-d-Ala is replaced, m
204 o the understanding of widespread carotenoid biosynthesis pathways in bacteria, Salinispora carotenoi
205 dizing 3-phosphoglycerate in the main serine biosynthesis pathway, in addition reduce alpha-ketogluta
206 , ADCK4 interacted with members of the CoQ10 biosynthesis pathway, including COQ6, which has been lin
207 le for AhR as a regulator of the cholesterol biosynthesis pathway independent of its DRE-binding abil
208 nt catalyst dephosphorylating the riboflavin biosynthesis pathway intermediate 5-amino-6-ribitylamino
210 acteria supports a model for a beta-diketone biosynthesis pathway involving members of these three pr
212 -expression analysis showed that the steroid biosynthesis pathway is activated in enzalutamide-resist
213 der aerobiosis, we show that the chlorophyll biosynthesis pathway is affected by excess copper result
215 in the methylerythritol phosphate isoprenoid biosynthesis pathway is an important anti-infective drug
217 of the methylerythritol phosphate isoprenoid biosynthesis pathway is catalysed by the iron-sulphur en
218 final step of the four-step dTDP-L-rhamnose biosynthesis pathway is catalyzed by dTDP-4-dehydrorhamn
219 The rate-limiting step in the de novo GSH biosynthesis pathway is catalyzed by glutamate cysteine
222 s Cryptococcus neoformans Because the purine biosynthesis pathway is essential for many metabolic pro
223 ese data establish that an intact pyrimidine biosynthesis pathway is essential for the growth of the
224 nstrates for the first time that the melanin biosynthesis pathway is functional in adipose tissue.
227 omplete in vivo analysis of the archaeal Sec biosynthesis pathway is still unavailable, and the exist
228 talyzes the rate-limiting step of the serine biosynthesis pathway, is a target of p53 in human melano
229 ng the only redox reaction of the pyrimidine biosynthesis pathway, is a well-characterized target for
230 des ent-kaurene oxidase 2 of the gibberellin biosynthesis pathway, is down-regulated in OsbZIP48(OE)
231 Although the parasite may hijack the host's biosynthesis pathway, it relies mainly upon its own argi
232 te levels of metabolites of the tetrapyrrole biosynthesis pathway leading to the production of chloro
233 la association via the induction of N-glycan biosynthesis pathways leading to modification of host gl
234 ontrast, overexpressing a complete cytokinin biosynthesis pathway leads to large, often fused spontan
235 Altogether, we demonstrate that fatty acid biosynthesis pathway manipulation can help overcome the
236 etabolism, nitrogen metabolism, and ethylene biosynthesis pathway might play a role in systemic salt-
237 urprisingly, we found that the NAD(+)de novo biosynthesis pathway (nadABC) can be deleted from M. bov
238 of these resistance mechanisms and androgen biosynthesis pathways, new anti-androgens and androgen-d
239 In plants, a proposed ascorbate (vitamin C) biosynthesis pathway occurs via GDP-D-mannose (GDP-D-Man
243 Although almost all enzymes involved in the biosynthesis pathway of JA have been identified and char
244 ession of several genes in the mannose donor biosynthesis pathway of M. tuberculosis and BCG grown in
245 decarboxylase (DDC), two key enzymes in the biosynthesis pathway of melanin, were cloned, and their
247 Free Man(7-9)GlcNAc2 is released during the biosynthesis pathway of N-linked glycans or from misfold
249 our results advance our understanding of the biosynthesis pathway of the chlorophylls and the formati
250 es described to date reside in the polyamine biosynthesis pathway of the human parasite Trypanosoma b
251 roles in stability and trafficking along the biosynthesis pathway of the receptor protein as well as
253 oorganisms either synthesize TPP via de novo biosynthesis pathways or uptake exogenous thiamine from
254 cosylation of Sp1, inhibiting the hexosamine biosynthesis pathway, particularly the enzyme O-GlcNAc t
257 how that glucose flux through the hexosamine biosynthesis pathway regulates growth factor receptor gl
258 f candidate genes putatively involved in the biosynthesis, pathway regulation, and transmembrane tran
262 f PABA or compounds downstream in the folate biosynthesis pathway restored transcriptional silencing
263 PP) is a rare inherited disorder of the heme biosynthesis pathway resulting in the accumulation of pr
264 absence of biotin, disruption of the biotin biosynthesis pathway results in cell death rather than g
265 with the majority of genes in the monolignol biosynthesis pathway, revealed the function of PviPRX9 i
266 d in adaptive metabolism, protein transport, biosynthesis pathways, stress resistance, and virulence
267 s activity, and adenosine triphosphate (ATP) biosynthesis pathways such as glycolysis and ATP repleni
268 isms that exist at every step of the protein biosynthesis pathway, such as alternative splicing and p
269 genes that function within the coenzyme Q10 biosynthesis pathway, suggesting that SRNS may be treata
270 l sequenced cyanobacteria encode hydrocarbon biosynthesis pathways, suggesting an important, undefine
271 finally established the first complete auxin biosynthesis pathway that converts tryptophan (Trp) to I
272 otein named BioJ is the enzyme of the biotin biosynthesis pathway that determines the chain length of
273 p conversion of Trp to IAA is the main auxin biosynthesis pathway that plays an essential role in man
275 the mevalonate and non-mevalonate isoprenoid biosynthesis pathways that produce metabolic phosphates
276 lencing the initial committed step of the JA biosynthesis pathway, they are severely attacked in natu
277 portant role of p53 in regulating the serine biosynthesis pathway through suppressing PHGDH expressio
278 1, thereby enabling the cysteine-based thiol biosynthesis pathway to adjust to light and stress condi
279 biocatalysis, the amenability of carbapenem biosynthesis pathways to engineering for the production
280 ke enzymes in both leucine and glucosinolate biosynthesis pathways use a common mechanism and that me
281 variant of the diaminopimelate (DAP)-lysine biosynthesis pathway uses an LL-DAP aminotransferase (Da
283 al Gly was acquired from the medium, and the biosynthesis pathway was confirmed in experiments using
286 Most interestingly, the jasmonic acid (JA) biosynthesis pathway was significantly altered in the co
287 g the final enzyme of the de novo pyrimidine biosynthesis pathway, was deleted using Toxoplasma gondi
289 in the Mycobacterium tuberculosis fatty acid biosynthesis pathway, we predicted its possible ligands
290 s predictions, perturbations in the flavonol biosynthesis pathway were detected in cyp78a9, cyp78a8 c
291 hile utilizing lifestyle specific amino acid biosynthesis pathways (where possible) to determine prot
292 ch has been utilized to emulate the coumarin biosynthesis pathway, which features a key photochemical
293 at Gram-positive pathogens use a unique heme biosynthesis pathway, which implicates this pathway as a
294 e required for the activity of the flavonoid biosynthesis pathway, which is essential for the develop
295 ole for MFN2 in maintenance of the terpenoid biosynthesis pathway, which is necessary for mitochondri
296 meostasis, probably through the glycerolipid biosynthesis pathway, which may contribute mechanistical
297 These results suggest revisions to the MBT biosynthesis pathway while also identifying new targets
299 ed misregulation of genes in the C21 steroid biosynthesis pathway, with strong induction of cytochrom
300 e does not markedly affect the peptidoglycan biosynthesis pathway, with the exception of the nonfunct
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