ライフサイエンスコーパス: biosynthetic

1 common carbocyclic products of synthetic and biosynthetic [4+2] cycloaddition reactions.

2 use these sex differences by impeding the LT-biosynthetic 5-LO/FLAP complex assembly.

3 The aim of the study was to evaluate biosynthetic absorbable mesh in single-staged contaminat

4 In this prospective longitudinal study, biosynthetic absorbable mesh showed efficacy in terms of

5 ility of thiolase-based pathways and provide biosynthetic access to alpha-branched compounds as precu

6 ver, depletion of PFKFB4-attenuated cellular biosynthetic activity and resulted in the accumulation o

7 ene and phytofluene in both oranges, and the biosynthetic activity upstream of phytoene desaturase wa

8 he functional conservation of this important biosynthetic activity.

9 recent synthetic efforts that have leveraged biosynthetic advances and shed light on the mechanism of

10 The biosynthetic alpha-hydroxyketone rearrangement was appli

11 p chemical synthesis or the inability of the biosynthetic alpha1,6-fucosyltransferase (FUT8) to direc

12 nabinoid receptors, type 1 and 2, as well as biosynthetic and catabolic enzymes of the endocannabinoi

13 vance the knowledge and understanding of the biosynthetic and catabolic pathways that are relevant to

14 their organic substrates, enzymes performing biosynthetic and degradative halogenation chemistry util

15 opic analysis, chemical interconversion, and biosynthetic and mechanistic considerations.

16 ogs presents a significant challenge to both biosynthetic assembly and synthetic chemistry.

17 agellum uses a significant proportion of the biosynthetic capacities of the cell with each filament c

18 s may benefit by retaining the escherichelin biosynthetic capacity of the Yersinia HPI while eliminat

19 Nutrients-and by extension biosynthetic capacity-positively impact cell size in org

20 f the Yersinia HPI while eliminating the Ybt biosynthetic capacity.

21 fic promoters to express FCU-GFP enables the biosynthetic capture and in-depth analysis of mRNA dynam

22 es the COPII coat machinery to actively sort biosynthetic cargo from diffusible misfolded and residen

23 serted both at a neutral site and inside the biosynthetic cluster of interest, as a read-out for seco

24 We identify numerous biosynthetic clusters and experimentally validate a dive

25 the recruitment of tRNA editing proteins to biosynthetic clusters may have enabled the evolution of

26 discussion of the proposed biosyntheses and biosynthetic connections among the polycyclic furanobute

27 iosynthetic similarity of compounds revealed biosynthetic constraints in the covariation patterns of

28 This will facilitate identifying modules and biosynthetic constraints that may affect the outcome of

29 HKD2 and HKE2 are the major products of the biosynthetic crossover of the 5-lipoxygenase (5-LOX) and

30 led in S phase, due to both bioenergetic and biosynthetic defects.

31 To accommodate increased bioenergetic and biosynthetic demands, metabolic pathways are harnessed t

32 of glucose and glutamine catabolism to meet biosynthetic demands.

33 identify fatty acid synthesis as the primary biosynthetic determinant of Escherichia coli size and pr

34 l to shed light on the richness of bacterial biosynthetic diversity hidden in the environment, how it

35 However, only a small fraction of bacterial biosynthetic diversity is accessible using this strategy

36 ironmental factors correlate with changes in biosynthetic diversity.

37 tors that may drive the relationship between biosynthetic domain composition and latitude, from a pra

38 omal peptide biosynthesis was used to assess biosynthetic domain composition and richness in soils co

39 ironmental variables we measured, changes in biosynthetic domain composition correlate most closely w

40 nal basis for differences in soil metagenome biosynthetic domain compositions should help guide futur

41 We expect that more pericyclic biosynthetic enzymatic transformations remain to be disc

42 and subcellular localization of the key SPM biosynthetic enzyme 5-lipoxygenase (LOX) in vascular cel

43 at is only active when bound to the cysteine biosynthetic enzyme CysK.

44 n level is maintained to mitigate effects of biosynthetic enzyme inhibitors that substantially change

45 The guanine nucleotide biosynthetic enzyme inosine monophosphate dehydrogenase

46 M enzymes, including the molybdenum cofactor biosynthetic enzyme MoaA and the RNA methyltransferase R

47 nd on high levels of the iron-sulfur cluster biosynthetic enzyme NFS1.

48 s, the most important of which is the NAD(+) biosynthetic enzyme NMNAT2 that inhibits activation of t

49 in the context of repression of the key GSL biosynthetic enzyme UDP-glucose ceramide glucosyltransfe

50 e direct phosphorylation of the crucial heme biosynthetic enzyme, ferrochelatase (FECH) by protein ki

51 ed on the coexpression patterns of predicted biosynthetic enzyme-coding genes, and facilitates compar

52 t constrained by commensurate changes in the biosynthetic enzyme.

53 uring AMS we analyzed the roles of two lipid biosynthetic enzymes (FatM and RAM2) and an ABC transpor

54 e the ER subdomain, we screened phospholipid biosynthetic enzymes and found that the autophagy-initia

55 t kingdom, arise from specialized fatty acid biosynthetic enzymes and specialized acyltransferases.

56 de transcriptome analysis reveals that lipid biosynthetic enzymes are among the downstream targets of

57 CATALASE2 to inhibit auxin and jasmonic acid biosynthetic enzymes as a means to strengthen plant immu

58 ive activation of unreactive hydrocarbons by biosynthetic enzymes has inspired new synthetic methods

59 high-level, specific expression of key lipid biosynthetic enzymes located in the plastid and the endo

60 Here we show that, starting from a suite of biosynthetic enzymes, catalysts with complementary subst

61 s were unaffected by the targeting of purine biosynthetic enzymes, suggesting selective dependence of

62 Contrary to thylakoid lipid biosynthetic enzymes, the functions of most predicted ch

63 , in part, to their metabolism by eicosanoid biosynthetic enzymes.

64 fer chemistry to drive otherwise unfavorable biosynthetic equilibria.

65 nd Bursac demonstrated the ability to create biosynthetic excitable tissues from genetically engineer

66 resistance genes often found within the same biosynthetic gene cluster (BGC) responsible for manufact

67 Here, we identified and characterized the biosynthetic gene cluster (oka) of 1 and 2, then elucida

68 en integrated into the widely used antiSMASH biosynthetic gene cluster analysis pipeline and is also

69 Here we report cloning of the biosynthetic gene cluster for the beta-lactone antibioti

70 Sequencing of the dynemicin biosynthetic gene cluster in Micromonospora chersina pre

71 de synthetase-like-pteridine synthase hybrid biosynthetic gene cluster in Photorhabdus luminescens us

72 n commensal Escherichia coli contain the clb biosynthetic gene cluster that codes for small molecule

73 coded by clusters of co-located genes called biosynthetic gene clusters (BCs).

74 SM pathways, including all six known to form biosynthetic gene clusters (BGCs).

75 s, the Integrated Microbial Genomes Atlas of Biosynthetic gene Clusters (IMG-ABC).

76 a tool for targeted identification of custom biosynthetic gene clusters across 40 000 isolate microbi

77 gnized that there may be from 10(5) to 10(6) biosynthetic gene clusters as yet uncharacterized for po

78 nt work elucidates common microbiome-derived biosynthetic gene clusters encoding peptide aldehydes th

79 ely adopted to identify and characterize the biosynthetic gene clusters encoding the production of su

80 ry metabolite production is the abundance of biosynthetic gene clusters that are not expressed under

81 tly discovered to encode vast collections of biosynthetic gene clusters with diverse chemical potenti

82 discover small molecule elicitors of silent biosynthetic gene clusters.

83 dentified 49 putative specialized metabolite biosynthetic gene clusters.

84 structures from the primary sequences of the biosynthetic gene clusters.

85 as a positive regulator controlling suberin biosynthetic gene expression in the seed coat.

86 ll-molecule therapeutic modality (microbiome-biosynthetic gene therapy).

87 pecific promoter to increase expression of a biosynthetic gene, thereby modulating essential oil comp

88 n, potentiates the expression of cholesterol biosynthetic genes and increases cholesterol levels both

89 antly reduced the expression of capsaicinoid biosynthetic genes and the capsaicinoid content.

90 lated genes (including PYK10), glucosinolate biosynthetic genes and the genes for so-called specifier

91 considerable SL biosynthesis by releasing SL biosynthetic genes from an SL-dependent negative feedbac

92 Finally we demonstrate how biosynthetic genes from fungi, bacteria, and plants can

93 o transcriptionally induce late stage biotin biosynthetic genes in low biotin conditions.

94 The discovery of iridoid biosynthetic genes in the medicinal plant Catharanthus r

95 The induction of phospholipid biosynthetic genes is accompanied by induction of the en

96 Here, we report the minimum set of biosynthetic genes required to generate cruciferous phyt

97 enome sequencing identified a likely pair of biosynthetic genes responsible for tryptorubin A's linea

98 ment of fungal burden, histology and GT/bmGT biosynthetic genes' mRNA induction.

99 6% of modules contained two or more known SM biosynthetic genes, and module genes were enriched in SM

100 that by promoting the expression of arginine biosynthetic genes, especially argB gene, the ciaR mutat

101 nce of intact, disrupted, and absent capsule biosynthetic genes, indicating that urogenital colonizat

102 strategies work at three levels: introducing biosynthetic genes, using transcription factors, and imp

103 (HCAA) and jasmonic acid pathways, and their biosynthetic genes.

104 the up-regulation of flavonoid and terpenoid biosynthetic genes.

105 to be a member of the YUCCA family of auxin biosynthetic genes.

106 en and hyphal length but not induction of GT biosynthetic genes.

107 ransgenic expression of Rhodiola salidroside biosynthetic genes.

108 oops that link developmental regulators with biosynthetic genes.

109 Biosynthetic halogenation reactions range from simple ar

110 autophagy pathways can be thought of as the biosynthetic (i.e., anabolic) and degradative (i.e., cat

111 plant-derived ajmalan alkaloid pathways, the biosynthetic intermediate vomilenine can be transformed

112 5-amino-6-D-ribitylaminouracil (a vitamin B2 biosynthetic intermediate) with glycolysis metabolites s

113 ical synthesis of kalihinol C via a possible biosynthetic intermediate, "protokalihinol", which was t

114 tremendous chemical diversity from a single biosynthetic intermediate.

115 solates derived from the diversion of linear biosynthetic intermediates toward alternative cyclizatio

116 nsporters that control the movement of these biosynthetic intermediates within cellular compartments

117 oid A and berkeleyone A, and will aid future biosynthetic investigations into the origin of related n

118 Biosynthetic labeling of Plasmodium mRNAs is incredibly

119 ic reprogramming and its potential to induce biosynthetic liabilities that can be exploited for gliom

120 binding protein gene (fHbp), and the capsule biosynthetic locus, all of which are loci previously sug

121 o conserved proteins from the organofluorine biosynthetic locus, FthB and FthC, that are involved in

122 presence of a unique capsular polysaccharide biosynthetic locus.

123 ew presents our current understanding of the biosynthetic logic and enzymatic chemistry involved in t

124 The biosynthetic logic for their production is unknown and d

125 The biosynthetic machineries for construction of these disti

126 utilizing metabolic cell wall recycling and biosynthetic machineries.

127 which the glyoxylate pathway and amino acid biosynthetic machinery are required for mucin utilizatio

128 Consequently, the biosynthetic machinery for Fe/S clusters is evolutionari

129 o elucidate the dynamic nature of the cell's biosynthetic machinery.

130 orm lignin, but already have elements of its biosynthetic machinery.

131 ia functionalizing carrier proteins (CPs) of biosynthetic megaenzymes.

132 ield and a hernia defect at least 9 cm had a biosynthetic mesh (open, sublay, retrorectus, or intrape

133 CVH repair, intraperitoneal placement of the biosynthetic mesh significantly increased the risk of re

134 ring AD by sustaining cellular energetic and biosynthetic metabolism.

135 te and confer HCO activity in a heme-nonheme biosynthetic model in myoglobin.

136 Here, we use a biosynthetic model of HCO in myoglobin that selectively

137 A scopoletin biosynthetic mutant also shows increased susceptibility

138 A regulates CITF1 expression and that the JA biosynthetic mutant lacking the CITF1- and SPL7-regulate

139 ng and cell surface localization of multiple biosynthetic mutants.

140 he three allosteric committed enzymes in the biosynthetic network: threonine deaminase (also named l-

141 iverse specialized metabolites via multistep biosynthetic networks, including compounds of ecological

142 rSR positively regulates the staphyloxanthin-biosynthetic operon crtOPQMN, promoting survival of S. a

143 J, the product of an unannotated gene in the biosynthetic operon for NOS, as an acyl carrier protein

144 ct positive regulator of the staphyloxanthin-biosynthetic operon, crtOPQMN, but is epistatic to alter

145 The disparate biosynthetic origins and distant phylogenetic distributi

146 ranthus roseus has provided insight into the biosynthetic origins of this class of natural product.

147 is method to construct a functional lycopene biosynthetic pathway (11.9 kb encoding 10 genes) in Esch

148 ate, leading to engagement of the hexosamine biosynthetic pathway (HBP), increased O-GlcNAcylation, a

149 branch pathway in glycolysis, the hexosamine biosynthetic pathway (HBP), to increase uridine diphosph

150 higher stimulation of the fungal oxalic acid biosynthetic pathway also can contribute to the higher s

151 Biosynthetic pathway engineering can be employed to inse

152 The relatively short biosynthetic pathway experienced repeated cycles of inno

153 spectral database, enabled us to formulate a biosynthetic pathway for the biosynthesis of triptolide,

154 vered that the initial transformation in the biosynthetic pathway for the MeOPN modification of the C

155 ibitor of TarO, an early stage enzyme in the biosynthetic pathway for wall teichoic acid (WTA) synthe

156 followed transcript levels of the cytokinin biosynthetic pathway genes in a sliding developmental zo

157 ound that acetylcholine upregulated the PCTR biosynthetic pathway in ILC3s.

158 1 target genes as well as the enzymes of FAD biosynthetic pathway in triple-negative breast cancers,

159 nases involved in the inositol pyrophosphate biosynthetic pathway in Trypanosoma brucei: inositol pol

160 Based on these observations, a biosynthetic pathway is proposed for herbicidins.

161 oupled and that flux through the cholesterol biosynthetic pathway is required for the maximal SREBP-1

162 While the characterization of their biosynthetic pathway now reaches completion, still littl

163 We identified the biosynthetic pathway of 1 and completely mapped the enzy

164 ins have recently been identified within the biosynthetic pathway of each exopolysaccharide.

165 Although the biosynthetic pathway of MAs is well studied, the mechani

166 y into a rich family of natural products.The biosynthetic pathway of preakuammicine, a monoterpene pr

167 The biosynthetic pathway of the sphingolipids affords many o

168 at recognize intermediates of the vitamin B2 biosynthetic pathway presented by the monomorphic MR1 mo

169 risk of patient death, highlighting that the biosynthetic pathway producing OCDO is of major importan

170 efforts, but the enzymology of the okaramine biosynthetic pathway remains unexplored.

171 The hexosamine biosynthetic pathway requires glucose and glutamine for

172 and sufficient for the induction of a lipid biosynthetic pathway that is expressed in plant cells ac

173 ed to diversify a heterologous beta-carotene biosynthetic pathway that produced genetic variants with

174 ing protein 2a (PBP2a), is brought into this biosynthetic pathway to complete the cross-linking.

175 te to afford hydroxymethylphosphonate on the biosynthetic pathway to the commercial herbicide phosphi

176 amily-specific, trichome-localized acylsugar biosynthetic pathway using a combination of mass spectro

177 full elucidation of the Rhodiola salidroside biosynthetic pathway utilizing the first comprehensive t

178 but instead by disruption of the ergosterol biosynthetic pathway via inhibition of the 14alpha-demet

179 arative analyses of 17 genes involved in CPT biosynthetic pathway were validated by qRT-PCR.

180 ction of bacteriochlorophyll, which shares a biosynthetic pathway with haem up to protoporphyrin IX.

181 (or FamC1) protein encoded in the ambiguine biosynthetic pathway, an isomerocyclase that can rearran

182 idine synthase, two enzymes of the polyamine biosynthetic pathway, are critical for promastigote prol

183 etabolite in the nutrient-sensing hexosamine biosynthetic pathway, but this modest effect did not ful

184 patterns pinpoint alterations in hexosamine biosynthetic pathway, glycosylation and lipid metabolism

185 se mutations influence multiple steps in the biosynthetic pathway, minimally altering local domain st

186 omer that falls outside the canonical lignin biosynthetic pathway, the flavone tricin.

187 isoprenoid intermediates in the cholesterol biosynthetic pathway, the post-translational prenylation

188 andis was expressed to optimize the limonene biosynthetic pathway.

189 ansferase (AICARFT), an enzyme in the purine biosynthetic pathway.

190 tone antibiotic obafluorin and delineate its biosynthetic pathway.

191 tion of structural genes of the capsaicinoid biosynthetic pathway.

192 de as the final steps in the malbrancheamide biosynthetic pathway.

193 he activity of a specific enzyme in the heme biosynthetic pathway.

194 renylphenol, an early intermediate of the UQ biosynthetic pathway.

195 ylpropanoid pathways as well as the nicotine biosynthetic pathway.

196 iolin, an intermediate in the napyradiomycin biosynthetic pathway.

197 t the MeJA application activated the related biosynthetic pathway.

198 legans are reported to lack a de novo NAD(+) biosynthetic pathway.

199 l, rate limiting and regulatory genes of CPT biosynthetic pathway.

200 nd-alone catalysts, components of artificial biosynthetic pathways and biocatalytic or chemoenzymatic

201 man transporter ATP7B delivers copper to the biosynthetic pathways and maintains copper homeostasis i

202 trategies, including, among others, altering biosynthetic pathways and modifying the associations and

203 1) kinase promotes cell growth by activating biosynthetic pathways and suppressing catabolic pathways

204 bial natural products, and elucidating their biosynthetic pathways and their physiological effects, w

205 xplored bacterial lineages likely have novel biosynthetic pathways and unknown biochemical features.

206 host fatty acid incorporation into bacterial biosynthetic pathways by the Saureus fatty acid kinase (

207 nt genes of the phenylpropanoid and ethylene biosynthetic pathways during elicitation of resistance w

208 However, loss of glucose carbons to biosynthetic pathways early in glycolysis reduces the ca

209 unds to cope with their environments but the biosynthetic pathways for most of these compounds have n

210 ics that are covered in this minireview are: biosynthetic pathways for N-acyl amino acids, receptors

211 Metabolic co-regulation between biosynthetic pathways for secondary metabolites is commo

212 ard 11 recombinant CPs of different types of biosynthetic pathways from cyanobacterial and Streptomyc

213 Polyketide biosynthetic pathways have been engineered to generate n

214 l importance of these polysaccharides, their biosynthetic pathways have received limited attention.

215 Using transgenic mice with altered CYP lipid biosynthetic pathways in a mouse model of laser-induced

216 rtance of reactivation of AR-regulated lipid biosynthetic pathways in driving CRPC progression, and s

217 can be widely applied for rapid synthesis of biosynthetic pathways in general molecular biology labor

218 Metabolites produced by various biosynthetic pathways induced in both wheat and Brachypo

219 Biosynthetic pathways involving cytochrome P450-catalyze

220 ted tissues, accompanied by induction of the biosynthetic pathways leading from Glc to anthocyanins.

221 length core-LPS, which suggests that the Kdo biosynthetic pathways might not be essential in vivo in

222 by co-opting and regulating two independent biosynthetic pathways of floral volatile compounds.

223 ons are increasingly being recognized in the biosynthetic pathways of many structurally complex natur

224 pave the way for future characterisation of biosynthetic pathways of other basidiomycete natural pro

225 their medical and biological importance, the biosynthetic pathways of prenylated stilbenoids remain t

226 not alter ENaC delivery to the membrane from biosynthetic pathways or removal by endocytosis.

227 and identify the main genes involved in the biosynthetic pathways switched on by the elicitor.

228 Elucidating and characterizing biosynthetic pathways that generate X-X bonds could both

229 es involved in both protein biosynthesis and biosynthetic pathways, as well as of several stress-indu

230 with acceptor proteins for sulfur-containing biosynthetic pathways, elucidating mechanistic details o

231 orter substrate specificities to that of the biosynthetic pathways, exemplify how transporter substra

232 controls bacterial glycogen and plant starch biosynthetic pathways, the most common carbon storage po

233 Using enzymes from biosynthetic pathways, we have successfully developed a

234 novel possibilities for manipulating NAD(+) biosynthetic pathways, which is key for the future of th

235 c reprogramming; and (4) inhibition of lipid biosynthetic pathways.

236 ino group in the bacillosamine or perosamine biosynthetic pathways.

237 acid, S-adenosyl methionine (SAM) and folate biosynthetic pathways.

238 ed by so-called cross talk between different biosynthetic pathways.

239 le, tricarboxylic acid cycle, and amino acid biosynthetic pathways.

240 to emergence of substrates via evolution of biosynthetic pathways.

241 e therapeutically enhanced by blocking lipid biosynthetic pathways.

242 mical properties and alternatively-regulated biosynthetic pathways.

243 identification and characterization of their biosynthetic pathways.

244 gically harmful cross-talk between essential biosynthetic pathways.

245 s is most likely a general tool for specific biosynthetic pathways.

246 cated red cluster and exogenous hbn cluster) biosynthetic pathways.

247 requires a complete understanding of NAD(+) biosynthetic pathways.

248 studies expand our view of the combinatorial biosynthetic potential available in bacteria.

249 ence of the azide-functionalized sialic acid biosynthetic precursor Ac4 ManNAz.

250 s of bacteriochlorophyll and accumulates the biosynthetic precursor coproporphyrinogen III; a suppres

251 A) cycle is central to energy production and biosynthetic precursor synthesis in aerobic organisms.

252 Hapalindole U (4) is a validated biosynthetic precursor to ambiguine alkaloids, of which

253 om this pathway, and stealthin C, a proposed biosynthetic precursor to the kinamycins.

254 from a butenolide heterodimer via its likely biosynthetic precursor, 3,6-dideoxy-10-hydroxypseudoanis

255 C3 and C2 take turns to incorporate the two biosynthetic precursors into the growing depsipeptide ch

256 ys converting glycolytic NADH into the lipid biosynthetic precursors NADPH or acetyl-CoA.

257 ptides, are easily accessible either through biosynthetic precursors or chemical synthesis.

258 Following deglycosylation of these biosynthetic precursors, the resulting microbial oligosa

259 gioselectively halogenate a diverse range of biosynthetic precursors, with the halogens introduced of

260 O-glycosylated calcitonin and its analogous biosynthetic precursors.

261 ding protein FUS participates in several RNA biosynthetic processes and has been linked to the pathog

262 pmental path associated with upregulation of biosynthetic processes rather than a stepwise progressio

263 ostasis of periodontal formation, partly via biosynthetic processing of procollagen I and DMP1, provi

264 This suggests different biosynthetic properties between these two starches.

265 demonstrates the chemical feasibility of our biosynthetic proposal that andirolide N arises from 8alp

266 l shortly discuss their ecological roles and biosynthetic proposals.

267 Fluorescence tagged trichothecene biosynthetic proteins co-localize with the modified ER a

268 dy the binding interface between 2 important biosynthetic proteins.

269 one rearrangement is potentially a conserved biosynthetic reaction in this molecular class.

270 ht into how LepI regulates these bifurcating biosynthetic reaction pathways by using SAM as the cofac

271 y for the tricarboxylic acid cycle and other biosynthetic reactions creating a metabolic bottleneck.

272 reactions and has considerable relevance to biosynthetic reactions in organic chemistry.

273 ate (PPi) to inorganic phosphate Pi, driving biosynthetic reactions; they are essential for low cytos

274 ides experimental support for their proposed biosynthetic relationships.

275 ll-wall analogue was developed to hijack the biosynthetic rewiring of drug-resistant cells in respons

276 eukocytes stimulated ex vivo and defined the biosynthetic roles of 5-LOX and COX-2, using inhibitors

277 ts with implications for understanding their biosynthetic roles, mechanisms of catalysis, and evoluti

278 This makes the His biosynthetic route a promising target for herbicides, an

279 Putative biosynthetic route by means of polyketide synthatase bio

280 nthetase-tRNACUA pair and create an entirely biosynthetic route to incorporating phosphothreonine in

281 In this study, we describe a novel two-step biosynthetic route to obtain blastose, designed from a d

282 leaves express not only HSS but the whole PA biosynthetic route.

283 nal interplay between alternative nucleotide biosynthetic routes and ATR provides therapeutic opportu

284 thetic organisms by connecting oxidative and biosynthetic routes operating in different compartments.

285 oration of chemically defined LN-511-E8 into biosynthetic scaffolds represents a promising approach f

286 They stem from unusual biosynthetic sequences that lead to the incorporation of

287 Biosynthetic similarity of compounds revealed biosynthet

288 At the Golgi complex, the biosynthetic sorting center of the cell, the Arf GTPases

289 Biosynthetic sorting of newly synthesized transmembrane

290 al UQ biosynthesis rather than to a specific biosynthetic step, because both ubiK and ubiJ mutants ac

291 involved in secondary modifications in late biosynthetic steps leading to the synthesis of highly ox

292 isoprenoid pathway, enzymes involved in late biosynthetic steps remain uncharacterized.

293 for discovery through the development of new biosynthetic strategies that cross synthetic with natura

294 e, we anticipate that chemical synthetic and biosynthetic studies will become increasingly interdepen

295 ugars to properly build and fold antibodies, biosynthetic substrates to fuel endoplasmic reticulum (E

296 velopment of low-cost hybrid water splitting-biosynthetic systems that mimic natural photosynthesis t

297 new insights on interdomain communication in biosynthetic systems.

298 One solution involves biosynthetic tagging of target RNAs.

299 kuammicine, a Strychnos alkaloid, an elusive biosynthetic transformation that has been investigated f

300 The studies, in particular, shed light on biosynthetic transformations performed by M. tuberculosi