ライフサイエンスコーパス: biosynthetic enzyme

1 a gene encoding a crucial catecholaminergic biosynthetic enzyme.

2 t constrained by commensurate changes in the biosynthetic enzyme.

3 ), a major sulfate-modifying heparan sulfate biosynthetic enzyme.

4 mine-beta-hydroxylase (DBH), a catecholamine biosynthetic enzyme.

5 or Ube4b fused to full-length Nmnat1, an NAD biosynthetic enzyme.

6 and sufficient for converting AOS into a GLV biosynthetic enzyme.

7 actor Sre1N that drives expression of sterol biosynthetic enzymes.

8 (miRNA) in the regulation of specific glycan biosynthetic enzymes.

9 , in part, to their metabolism by eicosanoid biosynthetic enzymes.

10 N-terminal dehydro amino acid by the cognate biosynthetic enzymes.

11 ndently of leaves, despite low expression of biosynthetic enzymes.

12 may recruit different isoforms of flavonoid biosynthetic enzymes.

13 leader peptide that is required to guide the biosynthetic enzymes.

14 eicosanoids by high expression of eicosanoid biosynthetic enzymes.

15 far by the lethality of null mutants in NAD biosynthetic enzymes.

16 f the precursor peptides and not just by the biosynthetic enzymes.

17 e low-abundance, Golgi membrane-bound pectin biosynthetic enzymes.

18 ation by disrupting the function of farnesyl biosynthetic enzymes.

19 increases in transcripts encoding flavonoid biosynthetic enzymes.

20 that inhibit key glycan-binding proteins or biosynthetic enzymes.

21 nscriptional activator of diverse amino acid biosynthetic enzymes.

22 d transcript levels of several potential IAA biosynthetic enzymes.

23 e substrates were prepared using purified HS biosynthetic enzymes.

24 to adversely affect expression of downstream biosynthetic enzymes.

25 PtdIns) phosphate effectors and sphingolipid biosynthetic enzymes.

26 citation in the case of fatty acid and lipid biosynthetic enzymes.

27 d expression of transcripts encoding thiamin biosynthetic enzymes.

28 nt yet understudied class of natural product biosynthetic enzymes.

29 has only eight homologs to the nine lipid A biosynthetic enzymes.

30 IPKSs), a large, poorly understood family of biosynthetic enzymes.

31 ficity and domain structure of these modular biosynthetic enzymes.

32 for DNA synthesis, which include nucleotide-biosynthetic enzymes.

33 amine levels and expression of catecholamine biosynthetic enzymes.

34 nal molecules that initiate the induction of biosynthetic enzymes.

35 t changes in the concentration of fatty acid biosynthetic enzymes.

36 eric complex that contains most of the CoQ10 biosynthetic enzymes.

37 nd the world reveals unexplored diversity in biosynthetic enzymes.

38 cts upstream of several genes encoding auxin biosynthetic enzymes.

39 ystemic production of JA-Ile required the JA biosynthetic enzyme 12-oxo-phytodienoic acid (OPDA) redu

40 arities to two non-SPASM proteins, butirosin biosynthetic enzyme 2-deoxy-scyllo-inosamine dehydrogena

41 s triggers ubiquitination of the cholesterol biosynthetic enzyme 3-hydroxy-3-methylglutaryl CoA reduc

42 ciated degradation (ERAD) of the cholesterol biosynthetic enzyme 3-hydroxy-3-methylglutaryl-coenzyme

43 and subcellular localization of the key SPM biosynthetic enzyme 5-lipoxygenase (LOX) in vascular cel

44 n the cytoplasmic:nuclear ratio of a key SPM biosynthetic enzyme, 5-lipoxygenase.

45 tations in the gene encoding the cholesterol biosynthetic enzyme 7-dehydrocholesterol reductase (DHCR

46 Trichothecene biosynthetic enzymes accumulate in organized smooth ER w

47 tin, on the platelet activating factor (PAF) biosynthetic enzymes, acetyl-CoA:lyso-PAF acetyltransfer

48 be explained when, in addition to effects on biosynthetic enzyme activities, as yet unidentified inhi

49 The purine biosynthetic enzyme Ade4-GFP formed foci in the absence

50 he large subunit of the rate-limiting starch biosynthetic enzyme, ADP-glucose pyrophosphorylase.

51 We have also identified fusions of polyamine biosynthetic enzymes agmatine deiminase and N-carbamoylp

52 lation of Robo receptors and heparan sulfate biosynthetic enzymes, allowing for precise control over

53 ively regulates this circuit at the level of biosynthetic enzyme and receptor expression.

54 tic pathway screens to identify the endpoint biosynthetic enzyme and thus the compound through which

55 molecular evidence of colocalization of eCB biosynthetic enzyme and type I mGluR mRNA in VTA neurons

56 oglycan (GAG) biosynthesis requires numerous biosynthetic enzymes and activated sulfate and sugar don

57 light on the fine substrate specificities of biosynthetic enzymes and confirm the potential sequence

58 e the ER subdomain, we screened phospholipid biosynthetic enzymes and found that the autophagy-initia

59 rehalose concentrations independently of the biosynthetic enzymes and independently of any applied st

60 unctional characterization of genes encoding biosynthetic enzymes and intracellular transporters.

61 unctional characterization of genes encoding biosynthetic enzymes and intracellular transporters.

62 e cytosol, this complex contains both murein biosynthetic enzymes and morphogenetic proteins, includi

63 olytic toxins that are recognized by the SLS biosynthetic enzymes and others that are intrinsically c

64 thylene production converge on one family of biosynthetic enzymes and overlay several independent rev

65 have yielded insights into large families of biosynthetic enzymes and pheromone receptors, although t

66 epithelial type II cells and MSCs expressed biosynthetic enzymes and receptors for LXA4.

67 up-regulated genes encoding proanthocyanidin biosynthetic enzymes and several novel uncharacterized M

68 t kingdom, arise from specialized fatty acid biosynthetic enzymes and specialized acyltransferases.

69 y unknown concerted interplay between the HS biosynthetic enzymes and suggesting the need to control

70 The identification of these biosynthetic enzymes and the heterologous reconstitution

71 the expression of genes encoding cholesterol biosynthetic enzymes and the synthesis of cholesterol de

72 rified, recombinant late stage peptidoglycan biosynthetic enzymes and their respective purified subst

73 a range of genes encoding putative flavonoid biosynthetic enzymes and transcription factors were alte

74 he dopamine (DA) neuron phenotype, including biosynthetic enzymes and transporters.

75 ACID3-OXIDASE2, encoding a gibberellin (GA) biosynthetic enzyme, and the levels of GA1 and GA4 are h

76 hermore, catecholamine levels, catecholamine biosynthetic enzymes, and sympathetic nerve fibers were

77 de transcriptome analysis reveals that lipid biosynthetic enzymes are among the downstream targets of

78 Expression of the alginate machinery and biosynthetic enzymes are controlled by the extracytoplas

79 n pea and maize (Zea mays) indicate that IAA biosynthetic enzymes are not the main enzymes for PAA bi

80 At the enzyme level, active sites of key biosynthetic enzymes are now pinpointed through a curate

81 hat all retinoid receptors and many retinoid biosynthetic enzymes are present in the fetal bowel at a

82 es (menaquinone, siderophore, and tryptophan biosynthetic enzymes) are structurally homologous and ma

83 CATALASE2 to inhibit auxin and jasmonic acid biosynthetic enzymes as a means to strengthen plant immu

84 Akt), that implicated several de novo purine biosynthetic enzymes as kinase substrates.

85 ling and cell growth, and suggest HS and its biosynthetic enzymes as potential targets in the treatme

86 als candidate genes encoding uncharacterized biosynthetic enzymes as shown using cytochromes P450 pot

87 ive immunolocalization that NAT8L is the NAA biosynthetic enzyme Asp-NAT.

88 n inability to identify the gene for the NAA biosynthetic enzyme aspartate N-acetyltransferase (Asp-N

89 this dehydration is catalyzed by lanthionine biosynthetic enzyme B (LanB) or LanB-like proteins.

90 Here all these sporopollenin biosynthetic enzymes but TKPR2 have been immunolocalized

91 udied extensively by genetic manipulation of biosynthetic enzymes, but chemical tools for probing GAG

92 ism that stops the expression of phytoalexin biosynthetic enzymes by blocking the antecedent signal t

93 has made it difficult to identify important biosynthetic enzymes by classical biochemical approaches

94 Here, we show that biosynthetic enzymes can display unexpected promiscuity,

95 Loss-of-function mutations in genes for heme biosynthetic enzymes can give rise to congenital porphyr

96 , suggesting that the nisin and prochlorosin biosynthetic enzymes can produce the correct ring topolo

97 Here we show that, starting from a suite of biosynthetic enzymes, catalysts with complementary subst

98 Dopamine beta-hydroxylase (DBH) is the biosynthetic enzyme catalyzing formation of norepinephri

99 essure, including a cascade of catecholamine biosynthetic enzymes, catecholamines themselves and ster

100 Here we show that the sphingolipid biosynthetic enzyme, ceramide kinase, is a novel regulat

101 encodes an isoform (SlCHI1) of the flavonoid biosynthetic enzyme chalcone isomerase (CHI), which cata

102 ta americana, an antibody raised against the biosynthetic enzyme choline acetyltransferase (ChAT) was

103 ed on the coexpression patterns of predicted biosynthetic enzyme-coding genes, and facilitates compar

104 GLYCEROL ACYLTRANSFERASE1 (a triacylglycerol biosynthetic enzyme) combined with suppression of the tr

105 sition should be highly dependent on certain biosynthetic enzyme concentrations [(+)-pulegone reducta

106 that all subsequently identified downstream biosynthetic enzymes contribute to the synthesis of at l

107 F-C promoted expression of the prostaglandin biosynthetic enzyme COX-2 in lymphatics, a response thou

108 The eicosanoid biosynthetic enzyme cyclooxygenase (COX)-2 has been impl

109 n Arabidopsis-specific paralog of the lignin-biosynthetic enzyme CYP84A1, has neofunctionalized relat

110 atent tRNase that requires activation by the biosynthetic enzyme CysK (O-acetylserine sulfhydrylase A

111 at is only active when bound to the cysteine biosynthetic enzyme CysK.

112 is a prominent EDRF, since mice lacking its biosynthetic enzyme, cystathionine gamma-lyase (CSE), di

113 ordance of CSA levels with expression of its biosynthetic enzyme cysteine dioxygenase 1 (CDO1).

114 scriptional silencing of the promoter of its biosynthetic enzyme, cytosolic phospholipase A2alpha.

115 In contrast to the Delta(7)-DA biosynthetic enzyme DAF-36, HSD-1 is dispensable for pro

116 cts, measured as >60% inhibition of the heme biosynthetic enzyme delta-aminolevulinic acid dehydratas

117 ctional segregation of endocannabinoid (eCB) biosynthetic enzymes diacylglycerol lipase-alpha (DAGLal

118 The pyrimidine biosynthetic enzyme dihydroorotate dehydrogenase (DHODH)

119 In addition, unique biosynthetic enzymes discovered from bacteria from the s

120 f T16H, to our knowledge, the first alkaloid biosynthetic enzyme displaying two isoforms encoded by d

121 the expression of a second key noradrenergic biosynthetic enzyme, dopamine beta-hydroxylase, which is

122 rily conserved extracellular role for NAD(+) biosynthetic enzymes during development and physiology.

123 biting protein synthesis of globins and heme biosynthetic enzymes during heme deficiency.

124 ion suggests that these heritable changes in biosynthetic enzyme expression represent primary genetic

125 f rapid progenitor expansion and profiled HS biosynthetic enzyme expression.

126 al levels, respectively, to control ecdysone biosynthetic enzyme expression.

127 Mutant cells lacking complex sphingolipid biosynthetic enzymes fail to properly maintain residence

128 uring AMS we analyzed the roles of two lipid biosynthetic enzymes (FatM and RAM2) and an ABC transpor

129 e direct phosphorylation of the crucial heme biosynthetic enzyme, ferrochelatase (FECH) by protein ki

130 tion of cystathionine gamma-lyase (CSE), the biosynthetic enzyme for cysteine, in Huntington's diseas

131 P-glucose dehydrogenase (Ugdh), an essential biosynthetic enzyme for GAGs.

132 hibits expression of Tph1, the rate-limiting biosynthetic enzyme for serotonin in enterochromaffin ce

133 ry CB1-expressing inputs and overexpress the biosynthetic enzyme for the endocannabinoid 2-arachidono

134 glycerol lipase-beta (DAGLbeta), a principal biosynthetic enzyme for the endocannabinoid 2-arachidono

135 These include proteinase inhibitors and biosynthetic enzymes for production of volatile terpenes

136 o production of three octaketide polyenes by biosynthetic enzymes for the 10-membered enediyne calich

137 Consequently, the biosynthetic enzymes for these sugars are attractive tar

138 triacylglycerol (TAG) requires not only the biosynthetic enzymes for unusual FAs but also efficient

139 Evolution of the glucosinolate biosynthetic enzyme from IPMDH results from a single ami

140 omic developments enable the direct study of biosynthetic enzymes from complex microbial communities.

141 Starch biosynthetic enzymes from maize (Zea mays) and wheat (Tr

142 action is required for transfer of cell-wall biosynthetic enzymes from the lateral to the mature divi

143 in fungal transcripts specifying an arginine biosynthetic enzyme, functions as a nascent peptide with

144 show that UBIAD1, a vitamin K2/menaquinone-4 biosynthetic enzyme, functions cell-autonomously to regu

145 s study, we examined the expression of their biosynthetic enzymes, FUT1, FUT2, B3GALT5 and ST3GAL2, i

146 Prostaglandin levels and prostaglandin biosynthetic enzyme gene expression were measured by liq

147 with differential regulation of a pheromone biosynthetic enzyme gene.

148 y creatine deficiency due to knockout of the biosynthetic enzyme (guanidinoacetate N-methyltransferas

149 ges in NO cofactor tetrahydrobiopterin (BH4) biosynthetic enzymes (guanosine triphosphate cyclohydrol

150 tABCD operon encoding four putative anthrose biosynthetic enzymes has been identified.

151 Inhibition of triacylglycerol (TAG) biosynthetic enzymes has been suggested as a promising s

152 ive activation of unreactive hydrocarbons by biosynthetic enzymes has inspired new synthetic methods

153 e targeted modifications of different lignin biosynthetic enzymes have permitted the generation of tr

154 Experimental approaches targeting carotenoid biosynthetic enzymes have successfully increased the see

155 enesis phenotype in mice deficient in the HS biosynthetic enzyme, heparan sulfate 2-O sulfotransferas

156 Absence of the biosynthetic enzyme, heparan sulfate 2-O-sulfotransferas

157 ch genic regions and transporters near known biosynthetic enzymes, highlighting how even a draft geno

158 imulate binding of UBIAD1 to the cholesterol biosynthetic enzyme HMG CoA reductase, which is subject

159 s sterol-accelerated ERAD of the cholesterol biosynthetic enzyme HMG-CoA reductase.

160 For example, the lysine biosynthetic enzyme homocitrate synthase was recently sh

161 ic compounds and wine extracts inhibited PAF biosynthetic enzymes, however in higher concentrations t

162 sativa) by down-regulation of the monolignol biosynthetic enzyme hydroxycinnamoyl coenzyme A:shikimat

163 Mutations in the gene encoding the purine biosynthetic enzyme hypoxanthine-guanine phosphoribosylt

164 es the endogenous synthesis of SA via the SA biosynthetic enzyme ICS1, with ICS1 required for CLO-ind

165 parallel, systematic RNAi knockdown of lipid biosynthetic enzymes identified enzymes required for div

166 Systematic variation of the set of biosynthetic enzymes illustrated how each affects glucan

167 ah2 was AKR1C3, which encodes a key androgen biosynthetic enzyme implicated in castration-resistant p

168 an unexpected nuclear role for a nucleotide biosynthetic enzyme in regulation of a potent tumor supp

169 results also show a decrease in NOS and BH4 biosynthetic enzyme in submandibular glands.

170 residues to govern expression of antibiotic biosynthetic enzymes in a phosphorylation-independent ma

171 egulated by distinct sets of heparan sulfate biosynthetic enzymes in an appropriate growth factor con

172 ple erythroid transcription factors and heme biosynthetic enzymes in immature erythroid cells.

173 DLPC treatment induces bile acid biosynthetic enzymes in mouse liver, increases bile acid

174 By expressing 4-OH-ICN biosynthetic enzymes in Saccharomyces cerevisiae and Nic

175 bust and configurable scaffold for arranging biosynthetic enzymes in the cytoplasm of Escherichia col

176 eart, we quantified the expression of NAD(+) biosynthetic enzymes in the human failing heart and in t

177 g those for beta-carotene, encode carotenoid biosynthetic enzymes in their intervals.

178 ogy offers immediate potential to lock these biosynthetic enzymes in their native binding states by p

179 us bacterial host and characterized all four biosynthetic enzymes in vitro.

180 HALCONE SYNTHASE, a gene encoding a flavonol biosynthetic enzyme, in guard cells, but not pavement ce

181 ed expression of SDHA and genes encoding CoQ biosynthetic enzymes, in association with reductions of

182 The signal cascade toward the expression of biosynthetic enzymes includes (1) the activation of phos

183 on of sigma(M) upregulates several cell wall biosynthetic enzymes including one, PBP1, shown here to

184 n of a variety of previously uncharacterized biosynthetic enzymes, including a YcaO domain protein an

185 Proper sulfation is mediated by biosynthetic enzymes, including exostosin-2 (Ext2), N-de

186 enes coding for paucimannosidic proteins and biosynthetic enzymes indicated a novel spatio-temporal b

187 The tryptophan biosynthetic enzyme indole-3-glycerol phosphate synthase

188 A (CoA) carboxylase (ACC), a key fatty acid biosynthetic enzyme, induced caspase-dependent cell deat

189 n level is maintained to mitigate effects of biosynthetic enzyme inhibitors that substantially change

190 The guanine nucleotide biosynthetic enzyme inosine monophosphate dehydrogenase

191 Inositol levels, maintained by the biosynthetic enzyme inositol-3-phosphate synthase (Ino1)

192 the utility of DNA scaffolds for assembling biosynthetic enzymes into functional metabolic structure

193 veloping evidence that several of the starch biosynthetic enzymes involved in amylopectin synthesis o

194 Previous studies of the biosynthetic enzymes involved in the assembly of scytone

195 The best characterized biosynthetic enzyme is GmhA, which catalyzes the convers

196 es, the only well-characterized endoperoxide biosynthetic enzyme is prostaglandin H synthase, a haem-

197 t in fah1 mutant plants, the activity of HCE biosynthetic enzymes is not limiting for HCE accumulatio

198 hat activates the genes for the mycolic acid biosynthetic enzyme KasA and the resuscitation promoting

199 Thus, much like the lasso peptide biosynthetic enzymes, lasso peptide isopeptidase has bro

200 tide for the lantibiotic lacticin 481 to its biosynthetic enzyme LctM allows the protein to act on co

201 Genetic mutations in the human Moco biosynthetic enzymes lead to a fatal metabolic disorder,

202 c diseases in which mutations in cholesterol biosynthetic enzymes lead to accumulation of sterol prec

203 A raises interesting questions regarding how biosynthetic enzymes leading to the salinosporamides pro

204 ombined activity of SFR2 and triacylglycerol-biosynthetic enzymes leads to the removal of monogalacto

205 high-level, specific expression of key lipid biosynthetic enzymes located in the plastid and the endo

206 ere absent in mBMMCs lacking CysLT1R and the biosynthetic enzyme LTC4 synthase, implying a requiremen

207 econciled by the recent finding that certain biosynthetic enzymes may be spatially organized into two

208 ions, implying that other foci-forming lipid biosynthetic enzymes might retain activity as well.

209 M enzymes, including the molybdenum cofactor biosynthetic enzyme MoaA and the RNA methyltransferase R

210 dehydrogenase anSME, and molybdenum cofactor biosynthetic enzyme MoaA provides support for the establ

211 dehydrogenase (BtrN) and molybdenum cofactor biosynthetic enzyme (MoaA).

212 rified, recombinant late stage peptidoglycan biosynthetic enzymes (MraY, MurG, FemX, PBP2) and their

213 ovalent inhibitor of the bacterial cell wall biosynthetic enzyme MurA from Enterobacter cloacae and E

214 lizes the activity of a series of nucleotide-biosynthetic enzymes (NBEs) whose expression is represse

215 report that ablation of the heparan sulfate biosynthetic enzyme NDST1 in murine endothelium (Ndst1EC

216 nd on high levels of the iron-sulfur cluster biosynthetic enzyme NFS1.

217 by a new downstream target of Hiw: the NAD+ biosynthetic enzyme nicotinamide mononucleotide adenyltr

218 e nicotinamide adenine dinucleotide (NAD(+)) biosynthetic enzyme nicotinamide mononucleotide adenylyl

219 Targeting the NAD(+) biosynthetic enzyme Nmnat to mitochondria was sufficient

220 gnaling cascade involving loss of the NAD(+) biosynthetic enzyme Nmnat/Nmnat2 in axons, activation of

221 condition caused by mutations in the NAD(+) biosynthetic enzyme NMNAT1.

222 s, the most important of which is the NAD(+) biosynthetic enzyme NMNAT2 that inhibits activation of t

223 tations in the gene encoding the cholesterol biosynthetic enzyme NSDHL are associated with the X-link

224 nuclease activity when bound to the cysteine biosynthetic enzyme O-acetylserine sulfhydrylase A (CysK

225 GM3 synthase (ST3GAL5) is the first biosynthetic enzyme of a- and b-series gangliosides.

226 using different strategies now show that the biosynthetic enzyme of d-serine, serine racemase (SR), i

227 licolor chromosome, including genes encoding biosynthetic enzymes of the antibiotic actinorhodin.

228 They can, however, identify the biosynthetic enzymes of these compounds-findings that ar

229 ranscript expression of genes encoding other biosynthetic enzymes or proteoglycan core proteins could

230 Purine biosynthetic enzymes organize into dynamic cellular bodi

231 ne by controlling stability of the polyamine biosynthetic enzyme, ornithine decarboxylase.

232 is thaliana), which is defective in a lignin biosynthetic enzyme p-coumaroyl shikimate 3'-hydroxylase

233 ied was PSD1, which encodes the phospholipid biosynthetic enzyme phosphatidylserine decarboxylase.

234 The pyrimidine biosynthetic enzyme Plasmodium falciparum dihydroorotate

235 then acts in conjunction with other steroid biosynthetic enzymes present in the decidual tissue to s

236 tial for cell growth, and therefore, the MSH biosynthetic enzymes present potential targets for inhib

237 egulated (ribosomal, chemotactic and primary biosynthetic enzymes) proteins in the CCR versus batch c

238 he expression of nuclear genes encoding heme biosynthetic enzymes, proteins required for mitochondria

239 harbored a mutated gene encoding the purine biosynthetic enzyme PurH.

240 ng superfamily that also includes the purine biosynthetic enzymes, PurM and PurL, NiFe hydrogenase ma

241 w enzymes, such as the mitochondrial proline biosynthetic enzyme PYCR1.

242 timize the stoichiometry of three mevalonate biosynthetic enzymes recruited to a synthetic complex an

243 out the molecular mechanisms by which NAD(+) biosynthetic enzymes regulate SIRT1 activity to control

244 nsfer RNA (tRNA) 47 years ago, yet the final biosynthetic enzyme responsible for Q-maturation, epoxyq

245 te pathway precursors, but no reports of the biosynthetic enzymes responsible for this conversion hav

246 In vitro characterizations of pseurotin biosynthetic enzymes revealed that the glutathione S-tra

247 h immunohistochemistry for catecholaminergic biosynthetic enzymes revealed the ventrolateral medulla

248 ting individual mutants for a rhamnose sugar biosynthetic enzyme (rmlC; TDP-4-keto-6-deoxy-d-glucose

249 Previous examination of the initial biosynthetic enzyme (Rv3377c/MtHPS) involved in isoTb bi

250 We have identified gene fusions of polyamine biosynthetic enzymes S-adenosylmethionine decarboxylase

251 activity of a key trypanosomatid spermidine biosynthetic enzyme, S-adenosylmethionine decarboxylase,

252 reticulum-, and mitochondria-localized lipid biosynthetic enzymes sequester into distinct foci.

253 g an increase in transcripts encoding the GA-biosynthetic enzyme SlGA20ox3, as well as a reduction in

254 oteasomal degradation of the key cholesterol biosynthetic enzyme, squalene monooxygenase.

255 that isoforms of all three classes of glucan biosynthetic enzyme (starch/glycogen synthases, branchin

256 replication because inhibition of pyrimidine biosynthetic enzymes substantially decreases the product

257 etabolites are likely formed when tryptophan biosynthetic enzymes substitute synthetic BT for native

258 ganization of several other cytosolic murein biosynthetic enzymes such as MraY, MurB, MurC, MurE and

259 perature or overexpression of the YUCCA1 IAA biosynthetic enzyme, suggesting that iar4 mutations may

260 s were unaffected by the targeting of purine biosynthetic enzymes, suggesting selective dependence of

261 n transcript abundance for the corresponding biosynthetic enzymes, suggesting that transcriptional re

262 Attempts to harness the catalytic prowess of biosynthetic enzyme systems, for both compound discovery

263 e, we show that mAb CA4 binds to the melanin-biosynthetic enzyme tetrahydroxynaphthalene reductase.

264 transcription of genes for the catecholamine biosynthetic enzymes TH and PNMT.

265 e interactions of the glycan substrates, the biosynthetic enzymes that act upon them, and the membran

266 These include two chlorophyll biosynthetic enzymes that explain the majority of tocoph

267 genes that encode HSPG core proteins and the biosynthetic enzymes that generate and modify HSPG sugar

268 bolism of cholesterol to bile acids, and the biosynthetic enzymes that generate cholestenoic acids ar

269 parasite-specific feature of these collagen biosynthetic enzymes that may be exploited in future par

270 Contrary to thylakoid lipid biosynthetic enzymes, the functions of most predicted ch

271 Among glycosaminoglycan (GAG) biosynthetic enzymes, the human beta1,4-galactosyltransf

272 One such substrate is the pyrimidine biosynthetic enzyme thymidylate synthase (EC 2.1.1.45),

273 substrate of this pathway is the pyrimidine biosynthetic enzyme thymidylate synthase (TS; EC 2.1.1.4

274 o control the expression level of all of the biosynthetic enzymes to produce heparin in CHO cells.

275 o canonical leader peptides in directing the biosynthetic enzymes to the substrate.

276 GalNAz) is converted by endogenous mammalian biosynthetic enzymes to UDP-GalNAz and then epimerized t

277 that targeted inhibition of heparan sulfate biosynthetic enzymes together with enzyme replacement mi

278 s prolongevity signal requires the serotonin biosynthetic enzyme TPH-1 in neurons and the serotonin r

279 ssential for the production of the serotonin biosynthetic enzyme Tph1.

280 al regulation of the rate-limiting serotonin biosynthetic enzyme tryptophan hydroxylase (TPH) are poo

281 rt crystal structures of the galactofuranose biosynthetic enzyme UDP-galactopyranose mutase (UGM) fro

282 in the context of repression of the key GSL biosynthetic enzyme UDP-glucose ceramide glucosyltransfe

283 t allows controlled degradation of a key LPG biosynthetic enzyme, UDP-galactopyranose mutase (UGM).

284 hile one encodes the essential peptidoglycan biosynthetic enzyme, UDP-N-acetylglucosamine enolpyruvoy

285 point the specific glycans and corresponding biosynthetic enzymes underlying a biological process.

286 We monitored spatial distribution of lipid biosynthetic enzymes upon glucose depletion in Saccharom

287 anscriptional activation of gibberellic acid biosynthetic enzymes via histone demethylation.

288 While expression of glutathione biosynthetic enzymes was unchanged, xCT, a component of

289 protectase in combination with other modular biosynthetic enzymes, we describe the total synthesis of

290 s, whereas candidates more similar to lignan biosynthetic enzymes were catalytically inactive with th

291 identified in the plastoglobule, whereas the biosynthetic enzymes were in the membranes.

292 Proteins corresponding to nine morphine biosynthetic enzymes were represented in the whole stem,

293 olysine that is generated by the pyrrolysine biosynthetic enzymes when the growth media is supplement

294 edominant microsomal localization of the NAA biosynthetic enzyme, which is surprising in view of what

295 o study how structure determines function in biosynthetic enzymes with proteins obtained by genetic e

296 ecause it allows promiscuous activity of the biosynthetic enzymes with respect to modification of the

297 aused by mutations in genes that encode haem biosynthetic enzymes with resultant buildup of cytotoxic

298 andidate genes encoding cellulose and lignin biosynthetic enzymes, with chemical wood property phenot

299 iles correlate with those of core fatty-acid biosynthetic enzymes, with maximal expression occurring

300 that altered expression/activity of androgen biosynthetic enzymes would regulate tissue availability