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1 andis was expressed to optimize the limonene biosynthetic pathway.
2 crucial plastidial enzyme in the carotenoid biosynthetic pathway.
3 ctivates dioxygen to perform its role in the biosynthetic pathway.
4 dical SAM enzyme involved in the menaquinone biosynthetic pathway.
5 iolin, an intermediate in the napyradiomycin biosynthetic pathway.
6 the pimelate moiety by a modified fatty acid biosynthetic pathway.
7 drocarbon lycopadiene via an uncharacterized biosynthetic pathway.
8 to minimize negative pleiotropy in a complex biosynthetic pathway.
9 es of oxidation reactions in the artemisinin biosynthetic pathway.
10 e second step of the alternative menaquinone biosynthetic pathway.
11 es taking part in the fully decoded betalain biosynthetic pathway.
12 his study provides new knowledge of the CFTR biosynthetic pathway.
13 netically controlled by the heparan sulphate biosynthetic pathway.
14 e (or homoserine betaine) and elucidated its biosynthetic pathway.
15 he E. coli serotype O157 (E. coli O157) O-PS biosynthetic pathway.
16 are shown to be products of the cyanobactin biosynthetic pathway.
17 and biochemical context of a natural product biosynthetic pathway.
18 t the MeJA application activated the related biosynthetic pathway.
19 primary building reactions in the isoprenoid biosynthetic pathway.
20 e limited access to material exported by the biosynthetic pathway.
21 legans are reported to lack a de novo NAD(+) biosynthetic pathway.
22 atalyzing the last step in the main ceramide biosynthetic pathway.
23 e to glucose and flux through the hexosamine biosynthetic pathway.
24 om phenylalanine through the phenylpropanoid biosynthetic pathway.
25 d N-acetylmannosamine kinase, in sialic acid biosynthetic pathway.
26 l, rate limiting and regulatory genes of CPT biosynthetic pathway.
27 at target enzymes in different areas of that biosynthetic pathway.
28 channeling metabolites into the chlorophyll biosynthetic pathway.
29 ansferase (AICARFT), an enzyme in the purine biosynthetic pathway.
30 tone antibiotic obafluorin and delineate its biosynthetic pathway.
31 tion of structural genes of the capsaicinoid biosynthetic pathway.
32 de as the final steps in the malbrancheamide biosynthetic pathway.
33 he activity of a specific enzyme in the heme biosynthetic pathway.
34 renylphenol, an early intermediate of the UQ biosynthetic pathway.
35 ylpropanoid pathways as well as the nicotine biosynthetic pathway.
36 s is most likely a general tool for specific biosynthetic pathways.
37 glycol-alkaloid (SGA), lignin and flavonoid biosynthetic pathways.
38 TOR) signaling, which affects ATP levels and biosynthetic pathways.
39 o finding diverse Mbns and elucidating their biosynthetic pathways.
40 lism and amino acid, nucleotide, and pigment biosynthetic pathways.
41 sity-generating metabolism in many different biosynthetic pathways.
42 caffold for the organization of heterologous biosynthetic pathways.
43 s and a suppression of ciliary and flagellar biosynthetic pathways.
44 various chloroplast-localized lipid/pigment biosynthetic pathways.
45 cated red cluster and exogenous hbn cluster) biosynthetic pathways.
46 rates in the PG and wall teichoic acid (WTA) biosynthetic pathways.
47 requires a complete understanding of NAD(+) biosynthetic pathways.
48 in, coenzyme A, and folate, as well as other biosynthetic pathways.
49 les, physically separated from endocytic and biosynthetic pathways.
50 athways and potentially other metal cofactor biosynthetic pathways.
51 regulatory substrates and turns off anabolic biosynthetic pathways.
52 c reprogramming; and (4) inhibition of lipid biosynthetic pathways.
53 ino group in the bacillosamine or perosamine biosynthetic pathways.
54 acid, S-adenosyl methionine (SAM) and folate biosynthetic pathways.
55 e therapeutically enhanced by blocking lipid biosynthetic pathways.
56 ed by so-called cross talk between different biosynthetic pathways.
57 le, tricarboxylic acid cycle, and amino acid biosynthetic pathways.
58 to emergence of substrates via evolution of biosynthetic pathways.
59 gically harmful cross-talk between essential biosynthetic pathways.
60 mical properties and alternatively-regulated biosynthetic pathways.
61 identification and characterization of their biosynthetic pathways.
62 is method to construct a functional lycopene biosynthetic pathway (11.9 kb encoding 10 genes) in Esch
63 e in glucose carbon allocation by uncoupling biosynthetic pathway activity, which could diminish the
64 higher stimulation of the fungal oxalic acid biosynthetic pathway also can contribute to the higher s
65 (or FamC1) protein encoded in the ambiguine biosynthetic pathway, an isomerocyclase that can rearran
66 on of (E,E)-geranyllinalool to TMTT The DMNT biosynthetic pathway and both monooxygenases are distinc
67 ur results identify new proteins in the heme biosynthetic pathway and demonstrate that Hem25p and its
68 adrenergic receptor both in the anterograde, biosynthetic pathway and during postendocytic recycling.
70 Together these results establish the MCTR biosynthetic pathway and provide mechanisms in tissue re
72 that CmlI catalyzes the ultimate step in the biosynthetic pathway and that the precursor is not bound
73 eukaryotes, ticks possess an incomplete haem biosynthetic pathway and, together with other (non-haema
74 nd-alone catalysts, components of artificial biosynthetic pathways and biocatalytic or chemoenzymatic
75 man transporter ATP7B delivers copper to the biosynthetic pathways and maintains copper homeostasis i
76 trategies, including, among others, altering biosynthetic pathways and modifying the associations and
78 ng of complex gene networks, such as natural biosynthetic pathways and multicomponent synthetic circu
79 plant species provides clues for unravelling biosynthetic pathways and regulatory circuits, an area t
80 iated with the abscisic acid and gibberellin biosynthetic pathways and results of biosynthetic inhibi
81 essential functions of NatA for development, biosynthetic pathways and stress responses in plants.
82 1) kinase promotes cell growth by activating biosynthetic pathways and suppressing catabolic pathways
84 bial natural products, and elucidating their biosynthetic pathways and their physiological effects, w
85 xplored bacterial lineages likely have novel biosynthetic pathways and unknown biochemical features.
86 Three enzymes of the Mentha essential oil biosynthetic pathway are highly homologous, namely the k
89 idine synthase, two enzymes of the polyamine biosynthetic pathway, are critical for promastigote prol
90 cellular proteases and suppressed pyrimidine biosynthetic pathway, argininosuccinate lyase-encoding,
91 ere incorporated into the branched violacein biosynthetic pathway as dCas9-dependent switches capable
93 es involved in both protein biosynthesis and biosynthetic pathways, as well as of several stress-indu
94 ddressed whether targets from the eicosanoid biosynthetic pathway, assessed by multiplexed expression
95 etabolite in the nutrient-sensing hexosamine biosynthetic pathway, but this modest effect did not ful
96 y, we created a synthetic lesion in the heme biosynthetic pathway by deleting the gene HEM15 encoding
97 is mobilized for incorporation into multiple biosynthetic pathways by a cysteine desulfurase complex
98 ion of the respective plant species-specific biosynthetic pathways by the phytohormone jasmonate.
99 host fatty acid incorporation into bacterial biosynthetic pathways by the Saureus fatty acid kinase (
101 The cytoplasmic steps in the peptidoglycan biosynthetic pathway, catalyzed by the Mur (A-F) enzymes
102 The penultimate enzyme in the histidine biosynthetic pathway catalyzes dephosphorylation of l-hi
103 of reelin (Reln), the inhibition of steroid biosynthetic pathway component genes and the activation
104 embrane and are produced through a multistep biosynthetic pathway conserved in most Gram-negative bac
105 ith potent antimicrobial activity, and their biosynthetic pathway contains two divergent, stand-alone
109 uggest that the activation of the hexosamine biosynthetic pathway directly increased OGT levels and a
110 e of the genetic variation that explains the biosynthetic pathways driving the diversity of alkaloids
111 nt genes of the phenylpropanoid and ethylene biosynthetic pathways during elicitation of resistance w
113 with acceptor proteins for sulfur-containing biosynthetic pathways, elucidating mechanistic details o
114 evidence-based understanding of the various biosynthetic pathways employed by bacteria to produce pr
115 It has recently become clear that plant biosynthetic pathway-encoding genes are sometimes densel
117 orter substrate specificities to that of the biosynthetic pathways, exemplify how transporter substra
119 nthesis of two members of the nine-step heme biosynthetic pathway: ferrochelatase (HemH) and an isozy
120 erive from the fluoroacetate/fluorothreonine biosynthetic pathway first discovered in Streptomyces ca
122 spectral database, enabled us to formulate a biosynthetic pathway for the biosynthesis of triptolide,
124 vered that the initial transformation in the biosynthetic pathway for the MeOPN modification of the C
125 ibitor of TarO, an early stage enzyme in the biosynthetic pathway for wall teichoic acid (WTA) synthe
126 on of BChlide c into BChlide e completes the biosynthetic pathways for all "Chlorobium chlorophylls."
127 ystem, some bacterial pathogens have evolved biosynthetic pathways for host-like sialic acids, wherea
128 unds to cope with their environments but the biosynthetic pathways for most of these compounds have n
130 ics that are covered in this minireview are: biosynthetic pathways for N-acyl amino acids, receptors
133 , relatively few enzymes associated with any biosynthetic pathway from ginkgo have been characterized
134 ard 11 recombinant CPs of different types of biosynthetic pathways from cyanobacterial and Streptomyc
136 d expression analysis of seven glucosinolate biosynthetic pathway genes (MYB28, CYP79F1, CYP83A1, SUR
137 followed transcript levels of the cytokinin biosynthetic pathway genes in a sliding developmental zo
139 patterns pinpoint alterations in hexosamine biosynthetic pathway, glycosylation and lipid metabolism
141 ize and morphology, whereas defects in other biosynthetic pathways had either a negligible or fatty-a
145 ral genes in the highly conserved carotenoid biosynthetic pathway have been well characterized in mul
146 medicinal qualities, very few anthraquinone biosynthetic pathways have been elucidated so far, inclu
148 l importance of these polysaccharides, their biosynthetic pathways have received limited attention.
151 ate, leading to engagement of the hexosamine biosynthetic pathway (HBP), increased O-GlcNAcylation, a
152 branch pathway in glycolysis, the hexosamine biosynthetic pathway (HBP), to increase uridine diphosph
153 could increase substrate for the hexosamine biosynthetic pathway (HBSP) that produces UDP-N-acetylgl
154 l. show that reengineering of the isoprenoid biosynthetic pathway in E. coli (to bypass the usage of
155 of LpxC--an essential enzyme of the lipid A biosynthetic pathway in Gram-negative bacteria and a val
159 nd in vivo evidence for the role of the DMNT biosynthetic pathway in resistance against P. irregulare
161 tients, we investigated the Maresin 1 (MaR1) biosynthetic pathway in these subjects and its role in r
162 1 target genes as well as the enzymes of FAD biosynthetic pathway in triple-negative breast cancers,
163 nases involved in the inositol pyrophosphate biosynthetic pathway in Trypanosoma brucei: inositol pol
164 uct the entire cultivated tomato acylsucrose biosynthetic pathway in vitro using sucrose and acyl-CoA
165 Using transgenic mice with altered CYP lipid biosynthetic pathways in a mouse model of laser-induced
167 nstruction of specific plant natural product biosynthetic pathways in dedicated microbial "chassis" h
168 rtance of reactivation of AR-regulated lipid biosynthetic pathways in driving CRPC progression, and s
169 can be widely applied for rapid synthesis of biosynthetic pathways in general molecular biology labor
171 olved in de novo lipogenesis and cholesterol biosynthetic pathways in livers of mice on either diet.
173 genomic context of key points within the MIA biosynthetic pathway including physically clustered gene
174 process that involves inhibition of multiple biosynthetic pathways including cell wall, DNA, and bact
175 e genome reduction entailed the loss of many biosynthetic pathways including those for numerous amino
176 enzymes function to initiate many important biosynthetic pathways including those leading to peptido
177 s talk between the phenylpropanoid and auxin biosynthetic pathways independent from the observed auxi
178 Well-characterized antagonism within the WTA biosynthetic pathway indicated that early steps would be
181 f the mycobacterial cell envelope, and their biosynthetic pathway is a well known source of antituber
184 f the mycobacterial cell envelope, and their biosynthetic pathway is one of the targets of first-line
185 quence homology predicts that the sioxanthin biosynthetic pathway is present in all of the Salinispor
186 tudies have indicated that the Wzy-dependent biosynthetic pathway is primarily responsible for produc
188 at flux through the plastidial phenylalanine biosynthetic pathway is reduced in PhpCAT RNAi lines, su
189 oupled and that flux through the cholesterol biosynthetic pathway is required for the maximal SREBP-1
190 study reveals that the M. tuberculosis PABA biosynthetic pathway is responsible for intrinsic resist
191 the consequence of blocking the artemisinin biosynthetic pathway is the redirection of sesquiterpene
192 ent anticancer drug camptothecin (CPT) whose biosynthetic pathway is unresolved due to the lack of ge
195 tion platform in the characterization of the biosynthetic pathway leading to the potent antioxidant c
196 ) with benzoic acid is the final step in the biosynthetic pathway leading to the production of cocain
197 ted tissues, accompanied by induction of the biosynthetic pathways leading from Glc to anthocyanins.
200 length core-LPS, which suggests that the Kdo biosynthetic pathways might not be essential in vivo in
201 se mutations influence multiple steps in the biosynthetic pathway, minimally altering local domain st
204 cytochrome P450 enzyme KtnC from the kotanin biosynthetic pathway of Aspergillus niger was expressed
207 hydrogenase-mediated cyclization step in the biosynthetic pathway of Euphorbia factors, illustrating
208 In this work, we elucidated the concise biosynthetic pathway of herquline A, a highly strained a
212 ntial glycosyltransferase that initiates the biosynthetic pathway of phosphatidyl-myo-inositol mannos
213 y into a rich family of natural products.The biosynthetic pathway of preakuammicine, a monoterpene pr
215 ne (preQ1) is the last free precursor in the biosynthetic pathway of queuosine that is crucial for tr
219 l and eukaryotic membranes and implicate the biosynthetic pathways of hopanoids and other order-modul
220 the key link to complete elucidation of the biosynthetic pathways of ingenol mebutate and other bioa
221 ons are increasingly being recognized in the biosynthetic pathways of many structurally complex natur
222 lly play a significant role in unveiling the biosynthetic pathways of natural products, here we demon
223 pave the way for future characterisation of biosynthetic pathways of other basidiomycete natural pro
224 their medical and biological importance, the biosynthetic pathways of prenylated stilbenoids remain t
225 ycosyltransferases as well as to investigate biosynthetic pathways of SRRPs as SRRP genetic loci are
226 s of glycosyltransferases and to investigate biosynthetic pathways of SRRPs because SRRP genetic loci
230 describe how to systematically target lipid biosynthetic pathways; optimize targeting conditions; ta
232 lack of knowledge regarding their underlying biosynthetic pathways, particularly for the abeo-abietan
234 at recognize intermediates of the vitamin B2 biosynthetic pathway presented by the monomorphic MR1 mo
235 risk of patient death, highlighting that the biosynthetic pathway producing OCDO is of major importan
236 aled that proteins involved in metabolic and biosynthetic pathways, protein synthesis and degradation
237 and Sm2 described here completes the maysin biosynthetic pathway, providing powerful tools for engin
239 ctase (CCR), an enzyme central to the lignin biosynthetic pathway, represents a promising biotechnolo
241 The enzyme SalBIII from the salinomycin biosynthetic pathway resembles other polyether epoxide h
243 Here, we provide a method using follow-on biosynthetic pathway screens to identify the endpoint bi
245 l that limiting flux through the cholesterol biosynthetic pathway spontaneously engages a type I IFN
248 l synthesis pathway is a ubiquitous cellular biosynthetic pathway that is attenuated therapeutically
249 and sufficient for the induction of a lipid biosynthetic pathway that is expressed in plant cells ac
250 ed to diversify a heterologous beta-carotene biosynthetic pathway that produced genetic variants with
251 olipid synthesis involves a highly conserved biosynthetic pathway that produces fundamental precursor
252 ynthase (PLPS) is a remarkable single-enzyme biosynthetic pathway that produces pyridoxal 5'-phosphat
253 tory up-regulation of genes in the terpenoid biosynthetic pathway that produces the LLO anchor dolich
254 evidence in support of a proposed network of biosynthetic pathways that can account for the formation
255 rokaryotes possess fatty acid synthase (FAS) biosynthetic pathways that comprise iterative chain elon
256 ts generates chorismate, which is drawn into biosynthetic pathways that form aromatic amino acids and
259 Nutrients are required for the multiple biosynthetic pathways that result in cell growth, and fa
262 e how mTORC2 modulates a glutamine-requiring biosynthetic pathway, the hexosamine biosynthesis pathwa
263 espite the immense therapeutic value of this biosynthetic pathway, the PBP-Lipid II association has n
264 isoprenoid intermediates in the cholesterol biosynthetic pathway, the post-translational prenylation
265 sistance through inactivation of the lipid A biosynthetic pathway, the products of which assemble the
266 ant mechanistic insights into this essential biosynthetic pathway, the structure of Lnt has remained
267 controls bacterial glycogen and plant starch biosynthetic pathways, the most common carbon storage po
268 as PKS product and the proposition of an FSA biosynthetic pathway, thereby unravelling the unique for
269 oexpression analysis to uncover the complete biosynthetic pathway to 4-hydroxyindole-3-carbonyl nitri
272 ing protein 2a (PBP2a), is brought into this biosynthetic pathway to complete the cross-linking.
273 es in trafficking SFAs into the glycerolipid biosynthetic pathway to form saturated phospholipids, wh
274 te to afford hydroxymethylphosphonate on the biosynthetic pathway to the commercial herbicide phosphi
275 gs highlight the importance of the polyamine biosynthetic pathway to viral replication, as well as it
277 rus (HCV) modulates intrahepatic cholesterol biosynthetic pathways to promote viral replication.
278 ich may fuel the shikimate and phenylalanine biosynthetic pathways to supply more aromatic amino acid
279 d product of the nutrient sensing hexosamine biosynthetic pathway, UDP-GlcNAc, as its substrate donor
280 the role of the RelA and SpoT enzymes in the biosynthetic pathway underlying these lipid modification
281 amily-specific, trichome-localized acylsugar biosynthetic pathway using a combination of mass spectro
282 udy, we engineered the pyrimidine nucleotide biosynthetic pathway using T4 bacteriophage genes to ach
283 we identify and characterize the indolmycin biosynthetic pathway, using systematic in vivo gene inac
284 full elucidation of the Rhodiola salidroside biosynthetic pathway utilizing the first comprehensive t
285 nction in the pyrroloquinoline quinone (PQQ) biosynthetic pathway via catalysis of carbon-carbon bond
286 but instead by disruption of the ergosterol biosynthetic pathway via inhibition of the 14alpha-demet
288 ic pathway was BAK1-dependent, the camalexin biosynthetic pathway was only partially dependent on BAK
289 ell growth and proliferation, and the serine biosynthetic pathway was recently identified as an impor
290 r crosstalk between the phospholipid and LPS biosynthetic pathways was revealed by experimental obser
291 ee genes of the recently elucidated betalain biosynthetic pathway, we demonstrate the heterologous pr
292 negative bacteria mutated for the riboflavin biosynthetic pathway, we show a strict correlation betwe
293 rs of the plastidic and cytosolic isoprenoid biosynthetic pathways, we demonstrated that the prenyl m
297 sence of PG results in the inhibition of Chl biosynthetic pathway, which impairs synthesis of PSI, de
298 novel possibilities for manipulating NAD(+) biosynthetic pathways, which is key for the future of th
299 ction of bacteriochlorophyll, which shares a biosynthetic pathway with haem up to protoporphyrin IX.
300 of cahuitamycin C proceeds via a convergent biosynthetic pathway, with one of the steps apparently b
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