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1 ular imaging studies of dopamine function in bipolar disorder.
2 in the membrane phospholipids metabolism in bipolar disorder.
3 of a high polygenic risk of schizophrenia or bipolar disorder.
4 ehavior, suggestive of some aspects of human bipolar disorder.
5 yet shown antidepressant efficacy in MDD and bipolar disorder.
6 eater genetic overlap with schizophrenia and bipolar disorder.
7 activation represent distinct dimensions of bipolar disorder.
8 these systems have been implicated, such as bipolar disorder.
9 agonists in the treatment and prophylaxis of bipolar disorder.
10 d in both chronic schizophrenia and euthymic bipolar disorder.
11 endations for the psychological treatment of bipolar disorder.
12 t and key negative outcomes in patients with bipolar disorder.
13 ll comorbidities except for schizophrenia or bipolar disorder.
14 t step forward in the clinical management of bipolar disorder.
15 h clinical features and course of illness in bipolar disorder.
16 stently been implicated in schizophrenia and bipolar disorder.
17 symptoms and executive function deficits in bipolar disorder.
18 NP) rs11764590 in MAD1L1 was associated with bipolar disorder.
19 ts occurring during maintenance treatment of bipolar disorder.
20 nd Care Excellence-recommended treatment for bipolar disorder.
21 of irritability, a symptom of both DMDD and bipolar disorder.
22 risk of converting to both schizophrenia and bipolar disorder.
23 diastolic blood pressure, serum albumin, and bipolar disorder.
24 ted in the pathogenesis of schizophrenia and bipolar disorder.
25 d may help to identify novel drug targets in bipolar disorder.
26 reas NRXN1-alpha expression was increased in bipolar disorder.
27 erlying pathophysiology of schizophrenia and bipolar disorder.
28 ured peer support for patients with remitted bipolar disorder.
29 ease in FA in the left posterior cingulum in bipolar disorder.
30 NF804A) is associated with schizophrenia and bipolar disorder.
31 ne, which codes for the Cav1.3 protein, with bipolar disorder.
32 1 patients with major depressive disorder or bipolar disorder.
33 of the sensorimotor network in patients with bipolar disorder.
34 ) and between openness and schizophrenia and bipolar disorder.
35 -52.3) converting to either schizophrenia or bipolar disorder.
36 stance-induced psychosis to schizophrenia or bipolar disorder.
37 nset in unaffected siblings of patients with bipolar disorder.
38 s the public health impact for patients with bipolar disorder.
39 ted in schizophrenia, Tourette syndrome, and bipolar disorder.
40 ood-stabilizing medication, in patients with bipolar disorder.
41 nd depression episodes that is a hallmark of bipolar disorder.
42 cluding schizophrenia, major depression, and bipolar disorders.
43 [0.55-0.74]), diagnosis of schizophrenia or bipolar disorder (0.55 [0.44-0.67]), cardiometabolic com
44 ve disorder (235.1 per 100000 person-years), bipolar disorder (216.0 per 100000 person-years), schizo
45 yped a Norwegian sample of 402 patients with bipolar disorder, 293 patients with schizophrenia, and 3
46 uding 29 analyses of the factor structure of bipolar disorder, 3 of activity data from experimental s
47 (736 patients vs. 668 control subjects) and bipolar disorder (536 patients vs. 489 control subjects)
48 onal MRI data acquired from 78 patients with bipolar disorder, 64 unaffected siblings, and 41 healthy
49 1 men included in the cohort, 4310 developed bipolar disorder; 784, schizoaffective disorder; 4823, s
50 as observed among adolescents with past-year bipolar disorder (94.2 [1.69]; P = .004), attention-defi
52 n patients with major depressive disorder or bipolar disorder, abnormalities in excitatory and/or inh
54 the rates of conversion to schizophrenia and bipolar disorder after a substance-induced psychosis, as
55 Lithium is widely used as a treatment for Bipolar Disorder although the molecular mechanisms that
56 nd psychiatric disorders like schizophrenia, bipolar disorder, Alzheimer's disease and autism, while
57 ommonly comorbid disorders of schizophrenia, bipolar disorder, Alzheimer's disease, and coronary arte
58 the inclusion criteria (18 schizophrenia, 16 bipolar disorder and 12 MDD) for chronically ill patient
60 6039769, that is associated with early-onset bipolar disorder and a higher gene expression level in h
61 to determine relapse rates for patients with bipolar disorder and a history of postpartum episodes.
63 s, attention-deficit hyperactivity disorder, bipolar disorder and antisocial personality disorder, ea
64 hanism both in schizophrenia and early-onset bipolar disorder and confirm the shared genetic vulnerab
65 ther activation is statistically abnormal in bipolar disorder and demonstrably distinct from mood, an
66 ers, such as post-traumatic stress disorder, bipolar disorder and depression, are also associated wit
67 anisms mediating irritability differ between bipolar disorder and DMDD, using a face emotion labeling
68 -wide association study based on CSF KYNA in bipolar disorder and found support for an association wi
70 pitulates some of the core features of human bipolar disorder and indicates that cortical microcircui
71 rominent cause of morbidity in patients with bipolar disorder and is strongly associated with suicide
75 ajor mood disorders, which primarily include bipolar disorder and major depressive disorder, are the
78 schizophrenia, euthymic (but not depressed) bipolar disorder and MDD compared with controls (P<0.01)
79 Participants aged 18 years or older with bipolar disorder and no episode in the preceding 4 weeks
82 ational Classification of Diseases codes for bipolar disorder and schizophrenia spectrum disorders.
83 reduced in number in post mortem studies of bipolar disorder and schizophrenia, and in chronically-s
84 stress increases adult risk for depression, bipolar disorder and schizophrenia, illnesses characteri
88 crease the vulnerability to both early-onset bipolar disorder and schizophrenia.SIGNIFICANCE STATEMEN
90 symptoms are a major cause of disability in bipolar disorder and there are few safe and effective tr
91 We included patients who had a diagnosis of bipolar disorder and were prescribed lithium (n = 2148),
92 ostpartum relapse in patients diagnosed with bipolar disorder and/or a history of postpartum psychosi
93 h a schizophrenia spectrum disorder, 26 with bipolar disorder) and 50 age-matched healthy control sub
94 cquisition, 71 youths (25 with DMDD, 24 with bipolar disorder, and 22 healthy youths) performed a lab
95 l 4,360 participants met DSM-IV criteria for bipolar disorder, and 310 met DSM-IV criteria for a mani
96 hiatric conditions, including schizophrenia, bipolar disorder, and attention-deficit/hyperactivity di
98 ng the familial clustering of schizophrenia, bipolar disorder, and autism spectrum disorders (ASD).
101 unced in schizophrenia (SZ), intermediate in bipolar disorder, and least in major depressive disorder
102 tial shared genetic risk with schizophrenia, bipolar disorder, and major depressive disorder and to i
103 ed comparison subjects and subjects with SZ, bipolar disorder, and major depressive disorder, and the
105 We tested whether the genetic load for MDD, bipolar disorder, and schizophrenia (SCZ) is increased i
106 Genomic profile risk scores (GPRSs) for MDD, bipolar disorder, and SCZ were based on meta-analysis re
107 f unintentional injury are poorly defined in bipolar disorder, and understanding drug associations wi
108 , including major depressive disorder (MDD), bipolar disorder, anxiety disorders, and schizophrenia.
109 orders.SIGNIFICANCE STATEMENT Depression and bipolar disorder are the most common mood disorders.
110 betes insipidus (lithium-NDI), patients with bipolar disorder are treated with thiazide and amiloride
111 has multiple alternative first exons, and a bipolar disorder-associated ANK3 variant has been shown
114 , with a focus on depression, schizophrenia, bipolar disorder, autism, anxiety and attention deficit/
115 volumes and specific mood disorders, such as bipolar disorder (BD) and major depressive disorder (MDD
119 e degree to which major depression (MDD) and bipolar disorder (BD) are associated with common and/or
129 fied several common variants associated with bipolar disorder (BD), but the biological meaning of the
130 m is the mainstay prophylactic treatment for bipolar disorder (BD), but treatment response varies con
131 T1D), type 2 diabetes (T2D), psoriasis (PS), bipolar disorder (BD), coronary artery disease (CAD), hy
133 ntified CACNA1C as a candidate risk gene for bipolar disorder (BD), schizophrenia (SCZ), major depres
135 ence supports a neurodevelopmental model for bipolar disorder (BD), with adolescence as a critical pe
144 s anticipation in depressed individuals with bipolar disorder (BDD) versus depressed individuals with
145 lygenic risk scores (PRS) for schizophrenia, bipolar disorder, BMI, waist-hip-ratio, insulin resistan
146 sive disorder (MDD), schizophrenia (SCZ) and bipolar disorder (BP) are common, disabling and heritabl
147 arch on resting functional brain networks in bipolar disorder (BP) has been unable to differentiate b
148 ng studies compare individuals affected with bipolar disorder (BP), at high familial risk of BP, and
149 nd circadian rhythms are central features of bipolar disorder (BP), often persisting between episodes
150 rder) were indistinguishable from those with bipolar disorder (BP)-II on clinical bipolar validators,
152 on-deficit/hyperactivity disorder (ADHD) and bipolar disorder (BPD) are frequently co-occurring and h
153 trum disorder (ASD), schizophrenia (SCZ) and bipolar disorder (BPD) are of great societal and medical
154 on, a core feature of schizophrenia (SZ) and bipolar disorder (BPD), and use functional magnetic reso
155 cases in each of four groups: schizophrenia, bipolar disorder (BPD), major depression (MD) and unaffe
156 ithium remains the gold standard in treating bipolar disorder but has unwanted toxicity and side effe
157 the correlation with violent criminality in bipolar disorder but none of the same correlation in sch
158 disorder is considered as a severe course of bipolar disorder, but it is unclear whether rapid cyclin
159 em brains of patients with schizophrenia and bipolar disorder by conducting a meta-analysis of existi
160 ein Ankyrin-G (AnkG), has been implicated in bipolar disorder by genome-wide association studies.
161 mproves depressive symptoms in patients with bipolar disorder by modulating function in components of
162 nia (Cohen d = 0.36, P < .001) and psychotic bipolar disorder (Cohen d = 0.33, P = .002) had signific
163 ing euthymia and depression in patients with bipolar disorder compared with healthy controls and othe
165 ment of daytime activity in individuals with bipolar disorder compared with other clinical or healthy
168 cent and young adult suicide attempters with bipolar disorder demonstrate less gray matter volume and
169 alization with a diagnosis of schizophrenia, bipolar disorder, depression, or anxiety was significant
170 s followed longitudinally, with diagnoses of bipolar disorder, depression, schizoaffective disorder a
172 havioral disorders, including schizophrenia, bipolar disorder, epilepsy, autism, Alzheimer's disease,
173 he brains of patients with schizophrenia and bipolar disorder exhibit decreased brain pH relative to
174 ychotic symptom severity in individuals with bipolar disorder experiencing a current psychotic episod
177 channel (LTCC) antagonists have been used in bipolar disorder for over 30 years, without becoming an
183 Although the importance of activation in bipolar disorders has been acknowledged for more than a
184 regarding lithium's antisuicidal effect for bipolar disorder have been limited due to nonrepresentat
186 ctorial trial (CEQUEL), patients with DSM-IV bipolar disorder I or II, who were aged 16 years or olde
187 or either major depressive disorder (MDD) or bipolar disorder I/II and who were currently experiencin
188 transcripts are altered in schizophrenia or bipolar disorder in comparison with non-psychiatric cont
190 fy building blocks of complex illnesses like bipolar disorder in hopes of uncovering the neurobiology
195 nd similarities between major depression and bipolar disorder is a necessary step to better understan
200 stabilizers, careful assessment to rule out bipolar disorder is indicated before initiating monother
201 der, but it is unclear whether rapid cycling bipolar disorder is linked to highly altered membrane ph
205 ssing evidence that risky decision-making in bipolar disorder is related to reward-based differences
206 er, in a substantial number of patients with bipolar disorder, long-term lithium therapy comes at the
207 ts that predispose to schizophrenia, autism, bipolar disorder, major depression and attention deficit
208 er, autism spectrum disorder, schizophrenia, bipolar disorder, major depression, generalized anxiety
209 o, childhood cognitive ability, neuroticism, bipolar disorder, major depressive disorder and schizoph
210 ultiple neuropsychiatric disorders including bipolar disorder, major depressive disorder, and schizop
211 o, attention deficit hyperactivity disorder, bipolar disorder, major depressive disorder, neuroticism
212 was found for autism but not schizophrenia, bipolar disorder, major depressive disorder, or attentio
213 high complexity and the high heritability of bipolar disorder make it a compelling candidate for neur
214 r mania, however, depressed individuals with bipolar disorder may differ from those with major depres
215 thogenesis of psychiatric disorders, such as bipolar disorder, may be ascribed to a complex gene-envi
216 ve disorder, and 129 patients with psychotic bipolar disorder (mean [SD] age, 35.1 [12.0] years; 281
217 roup psychoeducation, early in the course of bipolar disorder might have important benefits on the co
218 zophrenia spectrum disorders (n = 34903) and bipolar disorder (n = 29692), as well as unaffected cont
219 MN was examined in three related conditions: bipolar disorder (n = 9), unaffected first-degree relati
220 s old, and individuals diagnosed with either bipolar disorder (N=34) or major depressive disorder (N=
221 s old, and individuals diagnosed with either bipolar disorder (N=34) or major depressive disorder (N=
222 tic groups (major depressive disorder, N=32; bipolar disorder, N=50; schizophrenia, N=51; psychosis r
223 ry variants across autism, schizophrenia and bipolar disorder NGS cohorts demonstrating their impact
225 ng and significant protective effect against bipolar disorder (odds ratio = .31) and schizophrenia (o
226 or Health and Care Excellence guidelines for bipolar disorder offer a number of recommendations for t
227 s; 1.44, 1.13-1.83, p=0.003), earlier age of bipolar disorder onset (14 studies, 5733 participants; 1
228 hs, or were cognitively impaired, or who had bipolar disorder or psychosis or psychotic symptoms.
229 d until first occurrence of schizophrenia or bipolar disorder or until death, emigration, or August 2
230 each fits together to produce syndromes like bipolar disorder or why so many mental illnesses co-occu
231 of schizophrenia, schizoaffective disorder, bipolar disorder, or other psychotic illness according t
233 turalistic study, 907 adult outpatients with bipolar disorder participating in the Stanley Foundation
234 and phenomenology of mixed depression among bipolar disorder patients and qualitatively compared a r
235 probands with schizophrenia (SZ), psychotic bipolar disorder (PBD), and schizoaffective disorder; th
237 thium carbonate, a drug for the treatment of bipolar disorder, provides mood stability to mitigate re
238 or depression, presence of a suicidal plan, bipolar disorder, psychosis, posttraumatic stress disord
239 32; 95% confidence interval: 0.30-0.33) than bipolar disorder (r=0.23; 0.21-0.25), and large proporti
241 preparations remain first-line treatment for bipolar disorder, risk for development of renal insuffic
242 95% CI, 0.30-0.88) and for individuals with bipolar disorder (RR, 0.42; 95% CI, 0.17-0.69) and schiz
245 dies have suggested SORCS2 to confer risk of bipolar disorder, schizophrenia and attention deficit-hy
246 p of MDD and subtypes with psychiatric (MDD, bipolar disorder, schizophrenia) and metabolic (body mas
249 isorder, addiction, social anxiety disorder, bipolar disorder, schizophrenia, and attention-deficit/h
250 matic stress disorder, depressive disorders, bipolar disorder, schizophrenia, and substance use disor
252 inth Edition, Clinical Modification code for bipolar disorder, schizophrenia, or other psychotic diso
253 s of a mental disorder (depressive disorder, bipolar disorder, schizophrenia, substance use disorder,
254 rst-listed diagnoses of depressive disorder, bipolar disorder, schizophrenia, substance use disorder,
257 e highly recurrent and progressive course of bipolar disorder sometimes even in the face of conventio
258 Systematic Treatment Enhancement Program for Bipolar Disorder study, the authors analyzed point preva
259 revealed that all phenotypes (schizophrenia, bipolar disorder, substance misuse, and violent crime) w
260 f self-inflicted injuries, major depression, bipolar disorder, substance use disorder, and other ment
263 tly lower in patients with schizophrenia and bipolar disorder than in control participants, even when
264 ers that may be relevant to the treatment of bipolar disorder that can be tested in future clinical t
265 wever, for adults with psychotic disorder or bipolar disorder, the additional costs of involuntary co
266 idence for calcium signalling dysfunction in bipolar disorder, the therapeutic candidacy of this clas
268 of the clinical phenomenon of activation in bipolar disorder, to determine whether activation is sta
269 hiatric conditions, including schizophrenia, bipolar disorder, Tourette's syndrome, dementia, alcohol
271 sphocholine plus phosphocholine (GPC+PC)) in bipolar disorder using in vivo proton magnetic resonance
273 rs found that trait-related vulnerability to bipolar disorder was associated with reduced resting-sta
275 158 patients with schizophrenia spectrum or bipolar disorder, we assigned 58 771 (78%) to the deriva
276 k in patients with schizophrenia spectrum or bipolar disorder, we describe the derivation of a score
277 enriched for antipsychotics, while those for bipolar disorder were enriched for both antipsychotics a
279 national registers, 51,535 individuals with bipolar disorder were followed from 2005 to 2013 for tre
281 th subthreshold hypomania (SBP; subthreshold bipolar disorder) were indistinguishable from those with
282 t of patients with schizophrenia spectrum or bipolar disorder, which can be used as an adjunct to dec
283 METHOD: The study had 26 participants with bipolar disorder who had a prior suicide attempt (the at
284 es, the authors identified 2,307 adults with bipolar disorder who initiated therapy with methylphenid
285 es, the authors identified 2,307 adults with bipolar disorder who initiated therapy with methylphenid
286 treatment-emergent mania among patients with bipolar disorder who were concomitantly receiving a mood
287 14, with either major depressive disorder or bipolar disorder who were enrolled in one or more of 18
288 ts included all patients diagnosed as having bipolar disorder who were prescribed lithium, valproate,
289 behaviors and domains involved in mania and bipolar disorder will ultimately inform movement toward
290 s study of adolescents and young adults with bipolar disorder with and without a history of suicide a
291 Clinicians treating older patients with bipolar disorder with mood stabilizers need evidence fro
292 schizophrenia, schizoaffective disorder, and bipolar disorder with psychosis (N=711), their first-deg
293 r dopamine synthesis capacity is elevated in bipolar disorder with psychosis and how this compares wi
295 thium should be considered for patients with bipolar disorder with suspected suicidal intentions, alt
296 re mental illness (schizophrenia spectrum or bipolar disorder) with 574 018 patient episodes between
297 he attempter group) and 42 participants with bipolar disorder without a suicide attempt (the nonattem
299 as been much less investigation of mGluR5 in bipolar disorder, yet initial studies indicate that mGlu
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