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2 partial PKC agonist isophthalate derivative bis(1-ethylpentyl) 5-(hydroxymethyl)isophthalate induced
3 erocyclic system is described wherein the 2H-bis([1,2,3]triazolo)[5,1-a:4',5'-c]isoquinoline ring sys
4 tential using the slow voltage-sensitive dye bis-(1,3-diethylthiobarbituric acid)trimethine oxonol re
5 ur findings from these studies show that 3,5-bis[(1E)-2(2,6-dichlorophenyl)ethenyl]-1H-pyrazole 2l 1)
6 n compounds bearing tridentate dianionic 2,6-bis(1H-1,2,4-triazol-5-yl)pyridine luminophoric pincer l
9 alyst [Ir-IMes; [IrCl(COD)(IMes)], (IMes=1,3-bis(2,4,6-trimethylphenyl), imidazole-2-ylidene; COD=cyc
10 BDI(Mes)))(2)(mu-C(6)H(6))} (BDI(Mes) = N,N'-bis(2,4,6-trimethylphenyl)pentane-2,4-diiminate) with th
11 he case of K(2) [(NON)Al(NDipp)](2) (NON=4,5-bis(2,6-diisopropylanilido)-2,7-di-tert-butyl-9,9-dimeth
12 I) complex Re(eta(5)-Cp)(BDI) (1; BDI = N,N'-bis(2,6-diisopropylphenyl)-3,5-dimethyl-beta-diketiminat
13 s M(BDI(Dip)) (M = Al or Ga; BDI(Dip) = N,N'-bis(2,6-diisopropylphenyl)pentane-2,4-diiminate) in tolu
14 10 to +15% for polymers such as poly(2-(3,3'-bis(2-(2-(2-methoxyethoxy)ethoxy)ethoxy)-[2,2'-bithiophe
15 lewheel-type MOF structure that contains 4,7-bis(2-(4-pyridyl)-ethynyl) isoindoline N-oxide and 1,4-b
16 yridyl)-ethynyl) isoindoline N-oxide and 1,4-bis(2-(4-pyridyl)-ethynyl)-benzene pillars that connect
17 erent permeability enhancers ethylene glycol-bis(2-aminoethylether)-N,N,N',N'-tetraacetic acid (EGTA)
19 (PAEs), such as dibutyl phthalate (DBP) and bis(2-ethyl hexyl) phthalate (DEHP), are now increasingl
20 different food matrices, including BPA, BPS, bis(2-ethylhexyl) adipate, dibutyl adipate, hexadecyl me
22 stem PBDB-TF:Y6 (Y6 = 2,2'-((2Z,2'Z)-((12,13-bis(2-ethylhexyl)-3,9-diundecyl-12,13-dihydro-[1,2,5]thi
26 ully synthesized from 5,5'-(propane-2,2-diyl)bis(2-hydroxyisophthalaldehyde) and 1,2-cyclohexanediami
27 onate, and two new compounds, namely (Z)-1,6-bis(2-hydroxyphenyl)-3,4-diphenylhex-3-ene-1,6-dione (D1
28 s(dicarboximide)-co-2,2'-bithiophene-co-N,N'-bis(2-octyldodecyl)-naphthalene-1,4,5,8-bis(dicarboximid
29 tive ligand (tBu,Tol)DHP ((tBu,Tol)DHP = 2,5-bis((2-t-butylhydrazono)(p-tolyl)methyl)-pyrrole) activa
30 N cells with another GLS-exclusive inhibitor bis-2'-(5-phenylacetamide-1,3,4-thiadiazol-2-yl)ethyl su
35 rsibly responsive transformation between the bis[2]catenane and the bis-metallacage can be realized b
37 ectrometry confirm the formation of a cyclic bis[2]catenane with "infinity"-shaped topology via a 14-
38 2,2-diphenyl-1-picrylhydrazyl and 2,2'-azino-bis (3-ethylbenzothiazoline-6-sulfonic) acid assays show
39 tructed by linking the fullerene (C(60)) and bis(3,4,5-trimethoxyphenyl)aniline (BTMPA) to the alumin
40 n N-benzyl BINOL-phosphoramidite and a BINAP-bis(3,5-t-Bu-aryl)phosphine, are addressed through exhau
41 ysilane, (3-Aminopropyl)triethoxysilane, 1,3-Bis(3-aminopropyl)-1,1,3,3-tetramethyldisiloxane, reachi
44 me-peptide fragment then oxidized 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid) (ABTS) to g
45 p)(2)](2+) photosensitizer, where bmip = 2,6-bis(3-methyl-imidazole-1-ylidine)-pyridine, with simulta
46 atization strategy to convert the simple 1,4-bis(3-pyridyl)butadiynes 3a,b into the fjord-edge nitrog
49 nd releases high levels of the STING agonist bis-(3'-5')-cyclic dimeric adenosine monophosphate (c-di
50 e kinetics of the benzoate transfer from the bis(4-dimethylamino)-substituted benzhydryl benzoate Ar(
51 erpenetrated Hf MOF, linked by 1,4-phenylene-bis(4-ethynylbenzoate) ligands (Hf-peb), are induced by
55 4"'-(pyrazine-2,3,5,6-tetrayl) tetrakis (N,N-bis(4-methoxyphenyl) aniline) (PT-TPA) which can effecti
56 sidered the repurposing of (11)C-labeled 1,5-bis(4-methoxyphenyl)-3-(2,2,2-trifluoroethoxy)-1H-1,2,4-
58 l (CB7) catalyzes the hydrolysis reaction of bis(4-nitrophenyl)carbonate (1) but inhibits that of bis
60 ole-transporting large-bandgap polymer (poly[bis(4-phenyl)(2,4,6-trimethylphenyl)amine (PTAA)) is emp
61 (RSE) below 3% for aqueous solutions of 1,2-bis(4-pyridyl)ethylene (BPE), the lowest reported to dat
62 f the new complex, which incorporates a N,N'-bis(4-pyridylmethyl)-1,6-hexanediamine tether ligand, ar
63 symbolic methacrylate-based dental resins-2-bis[4-(2-hydroxy-3-methacryl-oxypropoxy)-phenyl]-propane
64 loped a novel c-Myc-targeting compound, N, N-bis (5-ethyl-2-hydroxybenzyl) methylamine (EMD), and pre
65 examined the effect of a new compound, N, N-bis (5-ethyl-2-hydroxybenzyl) methylamine (EMD), in targ
66 [3,2-b]indole-2,10-diyl)bis(methanylylidene))bis(5,6-difluoro-3-oxo-2,3-dihydro-1H-indene-2,1-diylide
67 (2-) is the doubly deprotonated form of [2,6-bis(5-(2,4,6-trimethylphenyl)-3-phenyl-1H-pyrrol-2-yl)py
68 ford the new dibrominated bis-indole ketone, bis(6-bromo-1H-indol-3-yl)methanone (3), followed by N-s
69 separated from the 19 structural isomers of bis[60]phenyl-C61-butyric acid methyl ester, using them
70 dmixed with the conjugated polymer poly(N,N'-bis(7-glycol)-naphthalene-1,4,5,8-bis(dicarboximide)-co-
71 posed of NIPAm, degradable crosslinker N, N'-bis (acryloyl) cystamine (BAC), sulfated 2-acrylamido-2-
75 sures the PSD reaction using distyrylbenzene-bis-aldehyde (DSB-3), whose reaction with PE produces a
78 deuteration that reinforces oxidation-prone, bis-allylic sites of PUFAs is a novel, nonantioxidant tr
80 , through the reactions of the corresponding bis(amides), M{N(SiMe(3) )(2) }(2) (thf)(2) , with (thf)
81 (ESR) measurements measurements of pristine, bis-, and tris-adducts of Gd(3)N@C(80) suggested that th
82 r study also reveals the mechanisms by which bis-ANS and related compounds modulate LLPS and identify
87 which we measure the host-guest binding of a bis(arylethynyl phenylurea) host with a chloride guest i
88 at room temperature to furnish symmetrical (bis)aryls in good yields under mild reaction conditions.
89 e reactions yield 1,3-bis(arylamino) and 1,3-bis(arylthio and alkylthio)indanes, respectively, which
92 and volumetric properties of DB1976, a model bis(benzimidazole)-selenophene diamidine compound with e
93 mbinatorial screening approach to identify a bis-benzodioxolylindolinone (azoffluxin) that synergizes
94 ne (D1) and (Z)-2,2'-(1,2-diphenylethene-1,2-bis(benzofuran-3(2H))-one) (D2), obtained in significant
96 different catalytic cycle, iodine yields the bis-bisulfate ester of ethylene glycol (HO(3)SO-CH(2)-CH
98 ondensation of easy manageable lithium alpha-bis(boryl)carbanions with carbonyl derivatives, the so-c
101 electrochemical study indicated that dithia-bis(calix)-sapphyrins are relatively easier to reduce bu
104 ing that the electronic properties of dithia-bis(calix)-sapphyrins were altered significantly upon pr
106 (DBF)/dibenzothiophene (DBT)-embedded dithia-bis(calix)-sapphyrins were synthesized by condensing 1 e
107 matographic purification afforded new dithia-bis(calix)-sapphyrins with two meso-sp(3) carbons in 5-7
110 xperiments revealed bis(phosphine)cobalt(II) bis(carboxylate)s were generated in catalytic reactions
111 sis of PiuA Fe(III)-bis-catechol and Ga(III)-bis-catechol and Ga(III)-(NE)(2) complexes by NMR spectr
113 entate Fe(III) complexes formed by mono- and bis-catechol species are important Fe sources in Gram-po
114 straction and alkane elimination to form the bis-cyclometalated derivatives [Ru(PPh(3))(C(6)H(4)PPh(2
115 geometry of 2 is that of a perfectly linear bis(cyclopentadienyl) sandwich complex, with the ground-
119 sent the successful introduction of multiple bis-deoxygalactosyl-carborane building blocks to the GRP
120 plex ((tBu)POCOP)Re(CO)(2) ((tBu)POCOP = 2,6-bis(di-tert-butylphosphinito)phenyl) that catalyzes CO(2
122 of 1,6,7,12-tetra(phenoxy)perylene-3,4:9,10-bis(dicarboximide) having either n-octyl groups (octyl-t
123 N,N'-bis(2-octyldodecyl)-naphthalene-1,4,5,8-bis(dicarboximide), and found to act as a simultaneous m
124 poly(N,N'-bis(7-glycol)-naphthalene-1,4,5,8-bis(dicarboximide)-co-2,2'-bithiophene-co-N,N'-bis(2-oct
125 olorimetric sensor using synthesized 3', 6'- bis(diethylamino) -2- ((3,4,5 trimethyl benzylidene) ami
127 Emmons (HWE) reaction of C(2) -symmetric 1,4-bis(diethylphosphonomethyl)benzene or 4,4'-bis(diethylph
128 4-bis(diethylphosphonomethyl)benzene or 4,4'-bis(diethylphosphonomethyl)biphenyl with C(3) -symmetric
129 his Article describes the development of 1,2-bis(diisopropylamino)-3-cyclopropenylium-functionalized
131 ]} (1; xant(P(i)Pr(2))(2) = 9,9-dimethyl-4,5-bis(diisopropylphosphino)xanthene) coordinates the Si-H
133 aH) in acetonitrile greater than that of 1,8-bis(dimethylaminonaphthalene) (DMAN), although its synth
134 n of mixed-valence class II and class II-III bis(dioxolene) bridging ligands with sufficiently weak i
135 egree of electronic communication within the bis(dioxolene) ligand and (2) the matching of cobalt and
137 eeds an expensive small molecule such as 2,8-bis(diphenyl-phosphoryl)dibenzo[b,d]thiophene (PPT) as t
138 )(dppe)H](+) (Cp* = C(5)Me(5)(-), dppe = 1,2-bis(diphenylphosphino)ethane), to a highly reactive, S =
140 (30) (dppm)(10) Cl(10) ](4+) (SD/Ag78a; dppm=bis-(diphenylphosphino)methane) that was synthesized thr
141 yrophosphate (PP-InsP) signaling family: 1,5-bis-diphosphoinositol 2,3,4,6-tetrakisphosphate (InsP(8)
142 (tBu)dmx: dimethylxanthine-bridged, cofacial bis-dipyrrin) were synthesized by deprotonation/metalati
143 ramolecular structures of cholesteryl-linked bis(dipyrrinato)zinc(II), to an exceptionally high level
144 l P-based key intermediates including a 1,4-(bis)electrophilic alpha,beta-unsaturated ketenyl phospho
147 amily of metal dichloride complexes having a bis-ferrocenyl-substituted pyridinediimine ligand was sy
149 zolium (EMIm) cations and high-concentration bis(fluorosulfonyl)imide (FSI) anions, with sodium bis(t
150 Al@Al is fully wetted by a 4 m potassium bis(fluorosulfonyl)imide-dimethoxyethane electrolyte (th
151 and Z isomers, indicating that the covalent bis-functionalization of C(60) can be controlled by ligh
153 oxy-3-methacryl-oxypropoxy)-phenyl]-propane (Bis-GMA) and 2-hydroxyethyl-methacrylate (HEMA)-and have
157 ne resulted in the formation of a conjugated bis-guanidinate (CBG)-supported aluminum dihydride compl
159 lyamine biosynthesis inhibitor methylglyoxal bis-(guanylhydrazone) (MGBG), but the molecular defects
161 rylisoxazoles, involving the reaction of 1,3-bis(het)arylmonothio-1,3-diketones with sodium azide in
162 amides, esters, (hetero)aromatic ynones, and bis(hetero)aryl ketones were synthesized in good-to-exce
163 Reductive elimination therefrom provides bis-heteroaryl products in a practical and efficient fas
164 is-pyrazoles as well as other pyrazole-based bis-heterocyclic molecules were prepared in moderate to
168 different FARs [diazolidinyl urea (DAU), 1,3-bis(hydroxymethyl)-5,5-dimethylimidazolidine-2,4-dione (
171 hich leads to the exclusive formation of the bis(imido) complexes [((ket)guan)Co(mu-NH)](2) (6) and [
172 tructures of the sponge-derived dibrominated bis-indole alkaloids, namely, echinosulfone A (2) and th
173 h triphosgene to afford the new dibrominated bis-indole ketone, bis(6-bromo-1H-indol-3-yl)methanone (
174 mate and are all carbon-bridged dibrominated bis-indoles: echinosulfone A (2) is a di(1H-indol-3-yl)m
175 presence of a trithiocarbonate and 2,2'-azo-bis isobutyro nitrile (AIBN) in toluene solution under a
176 ignificant concentrations of 5-coordinate Si bis-ligand complex being detected even under biologicall
177 ore effective than a previously used complex bis(maltolato)oxovanadium(V) in neuroblastoma cell lines
178 formation between the bis[2]catenane and the bis-metallacage can be realized by guest exchange, conce
179 tion-driven self-assembly of the interlocked bis-metallacage, by the 90 degrees Pt(II) heteroligation
180 eno[2',3':4,5]-thieno[3,2-b]indole-2,10-diyl)bis(methanylylidene))bis(5,6-difluoro-3-oxo-2,3-dihydro-
184 the Lewis acid Sc(3+) and transforms into a bis(mu-oxo)diiron(IV) complex, thus providing a syntheti
186 -like intermediate (high-valent diamond-core bis-mu-oxo-[Fe(IV)](2) unit) is involved in the reaction
189 ort a rationally designed redox-active Au(I) bis-N-heterocyclic carbene that induces ICD both in vitr
191 ylation of alkyl bromides and chlorides with bis(neopentylglycolato)diborane (B(2)neop(2)) mediated b
193 l-1,4,8,11-tetraazacyclotetradecane-1,8-diyl)bis(octadecan-2-ol) ([Co(L3)](2+) ) were synthesized to
194 teroarenes through challenging unsymmetrical bis-olefination process in a one-pot sequential fashion.
196 octadecanes via condensation reaction of 1,4-bis(organylphosphino)butane, formaldehyde, and primary a
197 We quantitatively establish the advantage of bis- over mono-intercalators before demonstrating the ap
202 of several CNS-directed, uncharged aliphatic bis-oximes holding promise for use as protonation-depend
203 heterocyclic amines and oxime groups of the bis-oximes resulted in equilibration among up to 16 dist
205 Oxime group reorientation of one of the bis-oximes, forcing it to point into the active center f
207 designing a catalyst for a model substrate (bis-p-nitrophenylphosphate) may provide wrong indication
208 nists are lipopeptides possessing the S-[2,3-bis(palmitoyloxy)propyl]-l-cysteine (Pam(2)Cys) motif an
209 ated carboxylic acids using readily prepared bis(phosphine) cobalt(0) 1,5-cyclooctadiene precatalysts
214 structures of 14-3-3sigma bound to mono- and bis-phosphorylated APN-derived peptides, which revealed
215 molecule that acts as receptor for mono- and bis-phosphorylated PIPs in a cell free environment.
217 readily generated by reaction of commercial bis(pinacolato)diboron with alkyl Grignard compounds.
219 ntials (V(on)) by synthesizing a specialized bis-PNP macrochelate that enables one-step Ni(II) bindin
220 2,3,9,10,16,17,23,24-Octakis (4-methyl-2,6-bis((prop-2-yn-1-yloxy)methyl)phenoxy) phthalocyaninato
221 l-1,4,8,11-tetraazacyclotetradecane-1,8-diyl)bis(propan-2-ol) ([Co(L2)](2+) ), and 1,1'-(4,11-dibenzy
222 om temperature and furnishes the pyrazine or bis-pyrazine-containing condensation products in good to
224 tions, and various symmetric and unsymmetric bis-pyrazoles as well as other pyrazole-based bis-hetero
227 ptimal nitrogen-nitrogen distance, bidentate bis(pyridine)-Au(III) complexes convert into dimers.
230 sed of two covalently strapped electron-rich bis-pyrrolidine PDI panels, nicknamed the "Green Box" du
231 zing distinct plant phenol-derived mono- and bis-quinone methide intermediates during different C-C a
232 y ligand scrambling, to form 1 and the U(VI) bis(silsesquioxane) complex, [U(Cy(7)Si(7)O(12))(2)] (3)
233 droxylation of sulfonylcyclopropanes using a bis(silyl) peroxide as the electrophilic oxygen source.
234 of 2 with silver(I) yields the monocationic bis(silylene) N(I) complex 4 with the closo-C(2) B(10) c
235 mediated by two divalent silicon atoms in a bis(silylene) scaffold, resulting in a silylene-stabiliz
236 nits are regenerated to furnish the isolable bis(silylene)-stabilized N(I) complex as an anion of 3 w
238 tom to the C(2)B(10) core to form an elusive bis(silylene)-stabilized Si(I) radical cation which unde
239 d from the redox reaction of the dipotassium bis(silylenyl)-nido-carboranate salt, 1,2-(LSi)(2)-1,2-C
240 lex ("silylone") stabilized by the chelating bis(silylenyl)-ortho-carborane ligand, 1,2-(LSi)(2)-1,2-
241 oach for the stereoselective construction of bis-spiroketals with thermodynamically similar stereoiso
243 singly, two of these structurally simple 3,5-bis(styryl)pyrazoles (2a and 2l) had concentrations whic
244 rotocol, we have synthesized a number of 3,5-bis(styryl)pyrazoles 2a-l, thus allowing for their scree
245 ken together, these results suggest that 3,5-bis(styryl)pyrazoles warrant further investigation as le
246 stigation of the mechanism of action of some bis(styryl)pyrazoles, demonstrating their potential as l
247 e hydroquinone cyclosiphonodictyol A and its bis(sulfato) from commercial (+)-sclareolide is reported
250 ding benzynes, is also demonstrated, and 2,5-bis(tert-butyldimethylsilyloxy)pyrroles are established
251 n processing a soluble derivative of QA, N,N-bis(tert-butyloxycarbonyl)-quinacridone (TBOC-QA), follo
252 the synthesis of a stereochemically-defined bis-tetrahydrofuran (bis-THF) derivative, which is one o
253 d HIV-1 protease inhibitors (PIs) containing bis-tetrahydrofuran (bis-THF) in a pseudo-C(2)-symmetric
255 vity relationship studies indicated that the bis-THF moiety can be attached at either the P2 or P2' p
256 ies of PIs were synthesized by incorporating bis-THF of darunavir on either side of the Phe-Phe isost
257 tereochemically-defined bis-tetrahydrofuran (bis-THF) derivative, which is one of the key structural
258 bitors (PIs) containing bis-tetrahydrofuran (bis-THF) in a pseudo-C(2)-symmetric dipeptide isostere a
260 ydes and ketones, the reaction scope for 3,6-bis(thiomethyl)-1,2,4,5-tetrazine, a survey of participa
262 ble selectivities to our previously reported bis-thiourea ortho-selective catalyst, with a catalyst l
264 ogen bond (ChB) donors integrated into a 3,5-bis-triazole pyridine structure covalently linked to ben
265 uble organic semiconductor 2,8-Difluoro-5,11-bis(triethylsilylethynyl)anthradithiophene (diF-TES-ADT)
267 action, with the derivatising agent N-methyl-bis-trifluoroacetamide, to substitute the exchangeable h
268 droxy compounds with iodobenzene diacetate, [bis(trifluoroacetoxy)]iodobenzene, and ammonium cerium(I
269 has been developed using the combination of bis(trifluoroacetoxy)iodobencene and trimethylsilyl brom
270 uorosulfonyl)imide (FSI) anions, with sodium bis(trifluoromethanesulfonyl)imide (NaTFSI) as a key add
271 lvation sheath of lithium ions enabling more bis(trifluoromethanesulfonyl)imide anion (TFSI(-) ) to c
272 n combined with a flexible triamine and zinc bis(trifluoromethanesulfonyl)imide, this ketone formed a
273 fferentiation experiments using alpha,alpha'-bis(trifluoromethyl)-9,10-anthracenedimethanol (ABTE) as
274 yphenyl) and Ar(F)-P=CPh(2) [1b: Ar(F) = 2,6-bis(trifluoromethyl)phenyl] have been prepared, isolated
275 ybenzamide (1, IC(50) 0.0192 muM) and N-[3,5-bis(trifluoromethyl)phenyl]-4-chloro-2-hydroxybenzamide
277 3-h]phenazine (bpph) and dCF(3)ppy is 2-(3,5-bis(trifluoromethyl-phenyl)pyridine), were found to be r
278 cid (PSA), and benzoic acid (BA) using N-3,5-bis-(trifluoromethyl)-phenyl-N-4-vinylphenyl urea (1) as
279 onic liquid (IL) 1-butyl-3-methylimidazolium bis(trifluoromethylsulfonyl)imide (BmimNTf(2)) as a func
280 an ionic liquid, 1-butyl-3-methylimidazolium bis(trifluoromethylsulfonyl)imide, and poly(vinylidene f
284 M-SEGPHOS, a bisphosphine ligand bearing 3,5-bis(trimethylgermanyl)-4-methoxyphenyl groups as the sub
285 hosphine ligand (TMG-SYNPHOS) containing 3,5-bis(trimethylgermanyl)phenyl groups on phosphorus and ap
287 e and TMS(2)S by the conjugate base, lithium bis(trimethylsilyl)amide (LiN(SiMe(3))(2)), and elementa
290 2H)] (1, (TMS)PS2H(2) = 2,2'-dimercapto-3,3'-bis(trimethylsilyl)diphenyl)phenylphosphine; H is a diss
291 responding pyrophoric primary phosphines and bis(trimethylsilyl)phosphines, have been isolated and ch
292 The anion [P(4)O(11)](2-), employed as its bis(triphenylphosphine)iminium (PPN) salt, is shown here
293 igold complexes of the general formula R-1,5-bis-triphenylphosphinegold(I) 1,2,3-triazolate (Au(2)-R)
295 phere at zirconium, imparted by the tethered bis(ureate) ligand, is crucial for the coordination of n
299 is(xanthylium)-biphenylene ([3](2+)) and 4,5-bis(xanthylium)-9,9-dimethylxanthene ([4](2+)) which pro
300 e studies are the bifunctional dications 1,8-bis(xanthylium)-biphenylene ([3](2+)) and 4,5-bis(xanthy