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   1 ers are required to detect patients with low BIs.                                                    
     2  btz is 3,3'-dimethyl-1,1'-bis(p-tolyl)-4,4'-bis(1,2,3-triazol-5-ylidene)), and show that the superio
  
     4 ogen, 4,4'-(thiazolo[5,4-d]thiazole-2,5-diyl)bis(1-(3-(trimethylammonio)propyl)pyridin- 1-ium) tetrac
     5 a Schiff base namely N,N'-(pyridine-2,6-diyl)bis(1-(4-methoxyphenyl) methanimine) (PM) on the corrosi
     6 t-butylphenyl phenyl phosphate (tb-PPP), and bis(1-chloro-2-propyl) phosphate (BCIPP)] using negative
  
     8 ion is readily reduced to a neutral, singlet bis-1,4-([3]cumulene)-p-carboquinoid as a result of the 
  
    10 measured using the dyes propidium iodide and bis-(1,3-dibutylbarbituric acid) trimethine oxonol to de
    11 iophene and electron-poor benzo[1,2-c:4,5-c']bis[1,2,5]thiadiazole subunits were introduced into the 
  
  
  
  
    16 G was detected selectively by ECL-generating bis(2,2'-bipyridine)-(4-(1,10-phenanthrolin-6-yl)-benzoi
    17 ((5,5'(di-p-topyldiaryldi(2-pyrrolyl)methane)bis(2,2'carbonyl)bis(azanediyl )) diethaneamine.2HCl] (8
    18  five novel brominated flame retardants, 1,2-bis(2,4,5-tribromophenoxy)ethane (BTBPE), decabromodiphe
    19 3,4,5-tetrabromobenzoate, EH-TBB), 2.42 (1,2-bis(2,4,6-tribromophenoxy)-ethane, BTBPE), 0.52 (2,4,6-t
    20 mobilization of [IrCl(COD)(IMes)], [IMes=1,3-bis(2,4,6-trimethylphenyl), imidazole-2-ylidene; COD=cyc
    21 on complex (SIMes)RuCl2 ((3)R21, SIMes = 1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidene
    22 pNi(NHC) (where Cp=cyclopentadienyl; NHC=1,3-bis(2,4,6-trimethylphenyl)imidazol-2-ylidene (IMes) or 1
  
    24 nzo[d,h][1,3,6,2]dioxazaboronine (3) and 1,4-bis(2,4,8,10-tetra-tert-butyldibenzo[d,h][1,3,6,2]dioxaz
    25 )Fe(NO)2](+) (R = Me, Et, Iso; (R)DDB = N,N'-bis(2,6-dialkylphenyl)-1,4-diaza-2,3-dimethyl-1,3-butadi
  
    27 actions on the vibrational spectra of a N-N'-bis(2,6-diisopropylphenyl)-perylene-3,4:9,10-bis(dicarbo
    28 ethylphenyl)imidazol-2-ylidene (IMes) or 1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene (IPr)), tow
  
  
    31 treptavidin pull-down assay showed that 4,11-bis(2-aminoethylamino)anthra[2,3-b]furan-5,10-dione (2a)
    32 s demonstrated that 2a and its analogue 4,11-bis(2-aminoethylamino)anthra[2,3-b]thiophene-5,10-dione 
    33 h AT-rich DNA, such as the N-phenylbenzamide bis(2-aminoimidazoline) derivatives 1 [4-((4,5-dihydro-1
    34 s with the intracellular Ca(2+) chelator 1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid tet
    35 P), bis(2-ethylhexyl) terephthalate (DEHTP), bis(2-ethylhexyl) adipate (DEHA)), and one FR (2,2-bis (
    36 ration step were: the applied potential 70V, bis(2-ethylhexyl) phosphate as the extractant in 1-octan
    37 ATBC), bis(2-propylheptyl) phthalate (DPHP), bis(2-ethylhexyl) terephthalate (DEHTP), bis(2-ethylhexy
  
    39 cceptor pair diindenoperylene (DIP) and N,N'-bis(2-ethylhexyl)-1,7-dicyanoperylene-3,4/9,10-bis(dicar
    40 ylhexyl-2,3,4,5-tetrabromobenzoate (EH-TBB), bis(2-ethylhexyl)tetrabromophthalate (BEH-TEBP), and bet
  
    42  antigen (PSMA), such as (68)Ga-labeled N,N'-bis(2-hydroxybenzyl)ethylenediamine-N,N'-diacetic acid (
    43 ylphenyl diphenyl phosphate (24DIPPDPP), and bis(2-isopropylphenyl) phenyl phosphate (B2IPPPP) being 
    44 g levels were determined to be 0.05 wt % 1,4-bis(2-methylstyryl)benzene singlet fluorophore and 0.28 
    45 l)-5,10-dihydroindeno[2,1-a] indene-2,7-diyl)bis(2-octylthieno[3,4-b]thiophene-6,4-diyl))bis(methanyl
    46 plasticizers (acetyltributyl citrate (ATBC), bis(2-propylheptyl) phthalate (DPHP), bis(2-ethylhexyl) 
  
    48 }(6) compound [Fe(PaPy3)NO](2+) (PaPy3 = N,N-bis(2-pyridylmethyl)amine-N-ethyl-2-pyridine-2-carboxami
    49 ion of 10,10'-bis[(p-toly)hydroxymethyl]-1,3-bis(2-thienyl)benzenediol with various 16-tripyrranes su
  
    51  inhibitors of GAC, with the prototype being bis-2-(5-phenylacetamido-1,2,4-thiadiazol-2-yl)ethyl sul
  
    53 inhibitors derived from the established N,N'-bis[2-hydroxy-5-(carboxyethyl)benzyl]ethylenediamine-N,N
    54 r spin-coated semiconducting PTB7 (poly[[4,8-bis[(2-ethylhexyl)oxy]benzo[1,2-b:4,5-b']dithiophene-2,6
    55 ), P3HT, and the liquid-crystalline poly(2,5-bis (3-tetradecylthiophen-2-yl)thieno[3,2-b]thiophene), 
    56 nium(V) oxo complex oxo(triphenylphosphine) (bis(3,5-di-tert-butyl-2-phenoxo)amido)rhenium(V), (ONO(C
    57 e positively charged analogues of privileged bis(3,5-trifluoromethyl)phenyl substituted thioureas, an
    58  glucose oxidase, peroxidase, and 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) react
    59 with greatest capacity to scavenge 2,2-azino-bis(3-ethylbenzthiazoline-6-sulphonic acid) (ABTS), 2,2-
    60 ith the NR4A1 small-molecule antagonists 1,1-bis(3-indolyl)-1-(p-hydroxy or p-carbomethoxyphenyl)meth
    61 surface diffusion of ultrathin films of N,N'-Bis(3-methylphenyl)-N,N'-diphenylbenzidine (TPD) (12 nm 
  
    63 ']dithiophe ne-2,7-diyl)bis(methanylylidene))bis(3-oxo-2,3-dihydro-1H-indene-2,1-diylidene))d imalono
  
    65 stor whose organic semiconductor is poly(2,5-bis(3-tetradecylthiophen-2-yl)thieno[3,2-b]thiophene) co
    66 such as poly(3-hexyl thiophene) and poly[2,5-bis(3-tetradecylthiophen-2-yl)thieno[3,2-b]thiophene], a
    67 colony morphogenesis by modulating levels of bis-(3',5')-cyclic-dimeric-guanosine (c-di-GMP), a secon
    68 c binding protein NspS and the transmembrane bis-(3'-5') cyclic diguanosine monophosphate (c-di-GMP) 
    69  intracellular secondary messenger c-di-GMP (Bis-(3'-5')-cyclic dimeric guanosine monophosphate), to 
    70 picrylhydrazyl radical (DPPH) and 2,2'-azino-bis-(3-ethylbenzo-thiazoline-6-sulfonic acid) diammonium
  
    72 O2(2-))](2+) ((S)P(MeAN), MeAN: N-methyl-N,N-bis[3-(dimethylamino)propyl]amine) that featured an elon
  
    74 he GIC using 4-tert-butylphenyldiazonium and bis(4-(tert-butyl)phenyl)iodonium salts, as well as phen
    75 cture incorporates three key features: (a) a bis(4-amino-3-hydroxyphenyl)squaraine core with bright d
    76 Alder reactions between 2 equiv of (E,E)-1,4-bis(4-bromophenyl)-1,3-butadiene and 1,4-benzoquinone le
  
    78  (+/-)MOD analogs, of which JJC8-016 (N-(2-((bis(4-fluorophenyl)methyl)thio)ethyl)-3-phenylpropan-1-a
  
    80 diphenylmethyl]-1H-pyrazole), senicapoc (2,2-bis-(4-fluorophenyl)-2-phenylacetamide), and NS6180 (4-[
    81 with exceptional photostability from the 4,6-bis(5'-dodecyl-[2,2'-bithiophene]-5-yl)thieno[3,4-c][1,2
    82 -b]thiophene-6,4-diyl))bis(methanylylidene)) bis(5,6-difluoro-3-oxo-2,3-dihydro-1H-indene-2,1-diylide
  
    84  after intravenous injection of MPO sensors (bis-5-hydroxytryptamide-tetraazacyclododecane [HT]-dieth
    85  prepared by cyclomerization reaction of 4,5-bis(6-carbazole-9-yl-hexylsulfanil)phthalonitrile in the
    86 {[(L)Cu(II)]2-(mu-OH)2}(OTf)2 (L = Me2TMPA = bis((6-methyl-2-pyridyl)methyl)(2-pyridylmethyl)amine) i
    87 es (W-OLEDs) composed of three emitters (2,7-bis(9,9-dimethyl-acridin-10-yl)-9,9-dimethylthioxanthene
  
  
    90 rin-trinitrofluorenone (TNF), and Hamilton's bis(acetamidopyridinyl)isophthalamide-barbiturate hydrog
  
    92  free radical polymerization using methylene bis-acrylamide, and ammonium persulphate as the cross li
  
  
  
    96 reacted with a water-soluble distyrylbenzene-bis-aldehyde (DSB-3), and provided strong discrimination
  
    98 in common, and a secondary cycle involving a bis-alkoxide species is avoided, thus explaining the lac
    99  with B(C6 F5 )3 to produce the zwitterionic bis(alkyl) hydridoborato Ce{C(SiHMe2 )3 }2 HB(C6 F5 )3 (
   100 b, with bipyrimidine (bipym) and a palladium bis-alkyl fragment, PdMe2, allows the rapid formation an
  
   102 peptides and proteins through site-selective bis-alkylation of cysteine residues present as disulfide
  
   104 alysis, the in situ formed neutral mono- and bis-alkynylated iron(II)-SciOPP complexes are consumed u
   105 how that increasing the number of deuterated bis-allylic carbons to include both C10 and C13 leads to
   106 in by abstracting hydrogen from one of three bis-allylic carbons within 1,4-cis,cis-diene units.     
  
  
  
  
  
  
  
   114 S-CC-MgBr) leads to a distribution of mono-, bis-, and tris-alkynylated iron(II)-SciOPP species due t
  
   116 hine ligand for the silver(I) salt and the 2-bis(aryl)methylpyrrolidine catalyst which was rationaliz
  
  
  
   120 gy and history of bisphosphonate treatment [+BIS Atypical: n = 12, BIS duration: 8.2 (3.0) y; +BIS Ty
   121 diaryldi(2-pyrrolyl)methane)bis(2,2'carbonyl)bis(azanediyl )) diethaneamine.2HCl] (8) selectively blo
   122  (2,2'-((1E,1'E)-((6-bromopyridine-2,3-diyl) bis(azanylylidene)) bis(methanylylidene diphenol) (BAMD)
  
   124  by Behavioral Inhibition/Activation System (BIS/BAS) correlated with accuracy during goal-directed l
   125 henylpyridin-2-yl)benzo[d]thiazole (L4), 2,6-bis(benzo[d]thiazol-2-yl)pyridine (L5), 2-(pyridin-2-yl)
   126 r benzoquinolines and terephthalaldehyde for bis-benzoquinolines synthesis was achieved with 68-75% y
   127 rization of enynes catalyzed by Pd(OAc)2 and bis-benzylidene ethylenediamine (bbeda) is a landmark me
  
   129 nating enzyme Uch37/UCHL5 and is targeted by bis-benzylidine piperidone RA190, which restricts cancer
   130 ctions are performed in aqueous acid using a bis(bipyridine)Ru catalyst to enable oxidation of substr
   131 ion complexes, a Pd(II)-nanohoop dimer and a bis(bipyridyl)ruthenium(II)-functionalized nanohoop, sho
   132 etrization led to the identification of 1,1'-bis[bis(dimethylamino)phosphino]ferrocene "DMAPF", a rea
   133  the opposite positions of the pi-conjugated bis(boranil) scaffold resulted in the formation of an un
  
   135 s of 1-amino-1H-indenes is reported from 1,2-bis(boronates) via a sequential Suzuki-Miyaura coupling/
  
  
   138      Herein we describe a large capsule-like bis-calix[4]pyrrole 1, which is able to host concurrentl
   139 port tetravalent cerium, uranium and thorium bis(carbene) complexes with trans C=M=C cores where expe
  
   141 de (ISE) membranes with tren-based tris-urea bis(CF3) tripodal compound (ionophore I) were found to e
   142 ethylhexyl) adipate (DEHA)), and one FR (2,2-bis (chloromethyl)-propane-1,3-diyltetrakis(2-chloroethy
  
  
  
   146 aring the C-C bond in ethane against that in bis(diamantane), and dispersion stabilization in the lat
  
  
   149 ng of three redox-active naphthalene-1,4:5,8-bis(dicarboximide) (NDI) units by dynamic imine chemistr
   150 bis(2,6-diisopropylphenyl)-perylene-3,4:9,10-bis(dicarboximide) (PDI) self-assembled monolayer adsorb
  
  
   153 s(2-ethylhexyl)-1,7-dicyanoperylene-3,4/9,10-bis(dicarboxyimide) (PDIR-CN2) has been chosen as a mode
   154 minum in some food samples, which used 3',6'-bis(diethylamino)-2-{[(1E)-(4-ethoxyphenyl) methylene] a
  
   156 m)3Fe identical withN reacts with 2 equiv of bis(diisopropylamino)cyclopropenylidene (BAC) to provide
   157 known, Ta(benzene)2 and Ta(dmpe)3 , dmpe=1,2-bis(dimethylphosphano)ethane, but these have only been a
   158 [L(Ar*)](-) (L(Ar*) = (Ar*N)2C(R), Ar* = 2,6-bis(diphenylmethyl)-4-tert-butylphenyl, R = NC(t)Bu2) fo
   159  = 2-aminomethyl-6-tolylpyridine, dppb = 1,4-bis(diphenylphosphino)butane) are highly active for the 
   160 catalyst, (dppf)Ni(o-tolyl)(Cl) (dppf = 1,1'-bis(diphenylphosphino)ferrocene), for Suzuki-Miyaura cou
  
   162 hoinositol pentakisphosphate) and 1,5-InsP8 (bis-diphosphoinositol tetrakisphosphate) are highly ener
   163 ination polymers (PCP) with integrated metal bis(dithiolene) units to achieve electrochemically contr
   164 hosphonate treatment [+BIS Atypical: n = 12, BIS duration: 8.2 (3.0) y; +BIS Typical: n = 10, 7.7 (5.
  
  
  
  
  
   170 e passivation molecules, 2,2'-(ethylenedioxy)bis(ethylamine) (EDA)-CDots and 3-ethoxypropylamine (EPA
   171 -butylammonium and EDBE = 2,2-(ethylenedioxy)bis(ethylammonium)), we find that only the latter, subje
   172 ally stacked heterostructures, consisting of bis(ethylenedithio)tetrathiafulvalene (BEDT-TTF)/C60 and
   173 linked by functionalized 4,4'-[1,4-phenylene-bis(ethyne-2,1-diyl)]-dibenzoate (peb(2-)) ligands, and 
  
   175 reported for the first time that a potassium bis(fluoroslufonyl)imide (KFSI)-dimethoxyethane (DME) el
  
   177 phacyclobutadiene [L2 Ge(mu-P)2 GeL2 ] 4 and bis(germyliumylidenyl)-substituted diphosphene [(L2 Ge-P
   178 w method allowing rapid entry to spirocyclic bis-heterocycles, in which inexpensive iron(III) catalys
  
  
  
  
  
   184 5% yield from the commercially available 2,2-bis(hydroxymethyl)propionic acid and used as the startin
   185 ombining the desymmetrization of a prochiral bis-hydroxymethyl group with the epimerization of a chir
  
  
  
  
  
   191 , and all of these pathways are inhibited by bis-indole-derived NR4A1 antagonists that inhibit nuclea
   192 the synthesis of various trifluoromethylated bis(indolyl)arylmethane, utilizing trifluoromethyltrimet
   193 ene intermediate to build up the alternative bis(indolyl)methane products, which may be useful syntho
  
   195 PD) reaction promoted by a chiral salen-type bis(lambda(5)-iodane) reagent, followed by an in situ re
   196    However, in recent years, a few mono- and bis(Lewis base)-stabilized borylenes have been isolated.
  
  
  
  
   201 )bis(2-octylthieno[3,4-b]thiophene-6,4-diyl))bis(methanylylidene)) bis(5,6-difluoro-3-oxo-2,3-dihydro
   202 -indaceno[1,2-b:5,6-b']dithiophe ne-2,7-diyl)bis(methanylylidene))bis(3-oxo-2,3-dihydro-1H-indene-2,1
   203 acationic macrocycle which contains two N,N'-bis(methylene)naphthalenediimide units inserted in betwe
   204 ding the cellular function and metabolism of bis(monoacylglycero)phosphate (BMP), an important but lo
   205 dentity of one highly expressed lipid class, bis(monoacylgylercoro)phosphate (BMP) lipids, and to dis
  
   207 end-on trans-peroxo, (T)P) and dicopper(III)-bis(mu-oxo) (L2Cu(III)2(O(2-))2: O) can be controlled th
  
   209 genation of the acyclic amido-chlorosilylene bis(N-heterocyclic carbene) Ni(0) complex [{N(Dipp)(SiMe
  
   211 metal-free approach to the synthesis of 2,2'-bis(naphthoquinones) using a Diels-Alder reaction of con
  
  
  
  
   216 (3.0) y; +BIS Typical: n = 10, 7.7 (5.0) y; +BIS Nonfx: n = 5, 6.4 (3.5) y; -BIS Typical: n = 11; -BI
  
  
  
   220 Enantioselection was achieved using a chiral bis(oxazoline) ligand, in many cases with high enantiose
   221 (btz)3](3+) (where btz is 3,3'-dimethyl-1,1'-bis(p-tolyl)-4,4'-bis(1,2,3-triazol-5-ylidene)), and sho
   222  synthesized by [3+3] condensation of 10,10'-bis[(p-toly)hydroxymethyl]-1,3-bis(2-thienyl)benzenediol
  
  
   225 (Fl)DAB)Rh(TFA)(eta(2)-C2H4) [(Fl)DAB = N,N'-bis(pentafluorophenyl)-2,3-dimethyl-1,4-diaza-1,3-butadi
   226  that the line between the recently proposed bis-pericyclic and Diels-Alder routes is blurred, and fa
   227 Hammett principle, however, reveals that the bis-pericyclic mechanism accounts for approximately 83% 
  
   229 hylthioxanthene-S,S-dioxide (DDMA-TXO2), 2,7-bis(phenoxazin-10-yl)-9,9-dimethylthioxanthene-S,S-dioxi
   230 Through serendipitous discovery, a palladium bis(phosphine) complex was identified as a catalyst for 
   231      A small-molecule inhibitor of pCRP (1,6-bis(phosphocholine)-hexane), which blocks the pCRP-micro
  
   233 Co(H)2BPin (1) and the air-stable cobalt(II) bis(pivalate) 4-Me-((iPr)PNP)Co(O2C(t)Bu)2 (2) compounds
  
   235 this complex harbors an active site tungsten-bis-pyranopterin cofactor with the metal being coordinat
   236  changes the course of reaction and leads to bis(pyrazol-4-yl)methane derivatives instead of the expe
  
  
  
  
  
   242 and [Co4(bptz)4(dbm)4].4MeCN (2) (bptz = 3,6-bis(pyridyl)-1,2,4,5-tetrazine; dbm = 1,3-diphenyl-1,3-p
  
   244 dical anions (2(*-) and 3(*-)) and then to a bis(radical anion) for 2(2-) but a dianion for 3(2-).   
   245 d with elevated levels of lipofuscin and its bis-retinoid components, such as N-retinylidene-N-retiny
   246 (I)((R)salophen)K] complexes or the [Co(II)2(bis-salophen)M2] (M = Li, Na) dimers that are present in
   247  An analysis of covariance showed that lower BIS scorers exhibited larger N1/P2 amplitudes across all
  
   249 n of CO2 by R3SiH to afford sequentially the bis(silyl)acetal, H2C(OSiR3)2, and CH4 (R3SiH = PhSiH3, 
  
   251 of thiolate 1 with carbene-stabilized diiodo-bis-silylene (2) (in a 2:1 ratio) in THF unexpectedly gi
  
   253 re evaluated for the untargeted detection of bis-sulfate metabolites (i) a precursor ion scan method 
   254   On the basis of the common behavior of the bis-sulfate metabolites two alternatives were evaluated 
  
  
  
  
   259 nstrate that the amine-specific cross-linker Bis(sulfosuccinimidyl)suberate (BS3), which is used for 
  
  
  
   263 lfonyl fluorides (AA monomers) and bisphenol bis(t-butyldimethylsilyl) ethers (BB monomers) using [Ph
  
  
   266  that treating cultured mouse podocytes with Bis-T-23 promoted stress fiber formation and focal adhes
  
  
   269 iangles were directly obtained by reacting a bis(terpyridinyl) ligand with a 60 degrees bite angle an
  
  
   272 ere we report the discovery of a macrocyclic bis-thiourea derivative that catalyzes stereospecific in
   273 ifferent Pd compounds and then encapsulating bis[tri(2-furyl)phosphine]palladium(II) dichloride in a 
  
   275 omplexes possessing two tridentate chelates (bis-tridentate) are known to be more robust compared to 
  
  
   278 onic liquid, 1-ethyl-2,3-dimethylimidazolium bis(trifluoromethanesulfonyl)imide (EMMIM TFSI), is inve
   279 E electrolyte (DME=1,2-dimethoxyethane, TFSI=bis(trifluoromethanesulfonyl)imide) and realize the best
   280 yl(diphenylphosphoramidate)trimethylammonium bis(trifluoromethanesulfonyl)imide, was synthesized and 
   281 sing two UCST-type TRILs, protonated betaine bis(trifluoromethyl sulfonyl)imide ([Hbet][Tf2N]) and ch
   282 eful (E)-alkenyl-CF3 building blocks and 1,1-bis(trifluoromethyl)-substituted alkenes can be prepared
   283 ectron-demand Diels-Alder reactions with 3,6-bis(trifluoromethyl)tetrazine were analyzed using the di
  
   285 o ionic liquids, 1-ethyl-3-methylimidazolium bis(trifluoromethylsulfonyl)amide and trihexyl(tetradecy
  
   287 yl sulfonyl)imide ([Hbet][Tf2N]) and choline bis(trifluoromethylsulfonyl)imide ([choline][Tf2N]) show
   288  liquid (RTIL) trihexyltetradecylphosphonium bis(trifluoromethylsulfonyl)imide ([P14,6,6,6][NTf2]) an
   289 ic liquid (RTIL) 1-butyl-3-methylimidazolium bis(trifluoromethylsulfonyl)imide (BmimNTf2) were invest
   290 e ionic liquid 1-butyl-1-methylpyrrolidinium bis(trifluoromethylsulfonyl)imide (BMP TFSI) and dimethy
  
   292 lock-poly(4-vinylbenzyl)-3-butyl imidazolium bis(trifluoromethylsulfonyl)imide, in a mixture of tetra
   293 125muL volume of 1-butyl-3-methylimidazolium bis(trifluorosulfonyl)imide [C4mim][Tf2N]) as extraction
  
   295   Herein, we report a novel fluorescent dye (bis(triphenylphosphonium) tetraphenylethene (TPE-TPP)) w
   296 typical: n = 12, BIS duration: 8.2 (3.0) y; +BIS Typical: n = 10, 7.7 (5.0) y; +BIS Nonfx: n = 5, 6.4
  
   298 II)-catalyzed oxidative macrocyclizations of bis(vinyl boronate esters) or ring-closing metathesis re
  
   300 nditional process analysis revealed that the BIS was a mediator of the association between the N1/P2 
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