ライフサイエンスコーパス: bithorax

1 s recapitulate the phenotypes of Enhancer of bithorax, a positive regulator of the Bithorax-Complex p

2 age T7 RNA polymerase were inserted into the bithorax (bx) regulatory region of the endogenous Ultrab

3 meotic genes of the Antennapedia (ANT-C) and bithorax (BX-C) complexes.

4 purpose we have investigated the Drosophila bithorax complex (BX-C) because genetic studies suggest

5 iption is prevented when Hox proteins of the Bithorax Complex (BX-C) bind to cis-regulatory elements

6 ch influences were first detected within the bithorax complex (BX-C) by E.B. Lewis, who coined the te

7 on of mobile element Delta 88 at +200 on the bithorax complex (BX-C) DNA map, 5' of all Abdominal-B (

8 anism necessary for the maintenance phase of Bithorax complex (BX-C) expression.

9 correct spatial expression of two Drosophila bithorax complex (BX-C) genes, abdominal-A (abdA) and Ab

10 The Drosophila Bithorax complex (BX-C) Hox cluster contains a bidirecti

11 The bithorax complex (BX-C) in Drosophila melanogaster is a

12 The Fab-7 boundary from the Drosophila bithorax complex (BX-C) is required for the parasegment-

13 Boundaries in the Bithorax complex (BX-C) of Drosophila delimit autonomous

14 At the Drosophila melanogaster bithorax complex (BX-C) over 330kb of intergenic DNA is

15 mplex (ANT-C) and the IAB5 enhancer from the Bithorax complex (BX-C) preferentially activate TATA-con

16 t bithoraxoid (bxd) ncRNAs of the Drosophila bithorax complex (BX-C) prevent silencing of Ultrabithor

17 source of new information is the Drosophila bithorax complex (BX-C).

18 ary element from the Drosophila melanogaster bithorax complex (BX-C).

19 es: the Antennapedia complex (ANT-C) and the bithorax complex (BX-C).

20 Mcp element from the Drosophila melanogaster bithorax complex (BX-C).

21 to initiate the activation of the Drosophila bithorax complex and define the domains of activity for

22 ax protein (TRX) binding elements within the bithorax complex and have found that within the bxd/pbx

23 The homeotic genes of the Drosophila bithorax complex are controlled by a large cis-regulator

24 -range enhancer-promoter interactions in the bithorax complex are regulated by a tethering element 5'

25 which is required for the functioning of the Bithorax complex boundary Fab-7, interacts specifically

26 b-7 cis-regulatory domains in the Drosophila Bithorax complex can function autonomously.

27 Other genes of the Bithorax Complex do not appear to participate in heart s

28 The Drosophila Bithorax Complex encodes three well-characterized homeod

29 Twenty insertions into the bithorax complex express (beta)-galactosidase in segment

30 from the Abdominal-B locus of the Drosophila bithorax complex facilitates the activity of a distantly

31 b-7 cis-regulatory domains in the Drosophila Bithorax Complex from early embryogenesis through to the

32 expression of both Antennapedia Complex and Bithorax Complex genes.

33 expression of both Antennapedia Complex and Bithorax Complex genes.

34 Fab-7 deletions in the bithorax complex have a novel gain-of-function phenotype

35 The bithorax complex in Drosophila melanogaster includes thr

36 A fragment from the middle of the Drosophila bithorax complex insert preferentially into the bithorax

37 The iab-4 noncoding RNA from the Drosophila bithorax complex is the substrate for a microRNA (miRNA)

38 ries of mutations have been recovered in the bithorax complex of D. melanogaster that transform the f

39 ivalents of the Antennapedia complex and the bithorax complex of Drosophila melanogaster.

40 In the bithorax complex of Drosophila, the IAB5 enhancer is loc

41 horax complex insert preferentially into the bithorax complex or into the adjacent chromosome regions

42 from the Abdominal-B locus of the Drosophila Bithorax complex overcomes an insulator, and facilitates

43 from the Abdominal-B locus of the Drosophila bithorax complex overcomes the enhancer-blocking activit

44 contrast, control test sites outside of the bithorax complex permitted Gal4, T7RNAP, and FLP activit

45 n this study, the chromatin structure of the bithorax complex was probed with three separate assays f

46 Several P insertions in the bithorax complex were tested, providing evidence that th

47 rns, reflecting the segmental domains of the bithorax complex where the elements reside.

48 One additional protein- coding gene in the bithorax complex, Glut3, a sugar-transporter homolog, ca

49 olycomb response element from the Drosophila bithorax complex, is able to mediate physical interactio

50 a domain boundary within the context of the bithorax complex, making Fab-7 one of the first boundary

51 Mcp mediates its regulatory function in the bithorax complex.

52 ility that other such genes occur within the Bithorax complex.

53 Abdominal-B homeotic genes at the Drosophila bithorax complex.

54 ogaster, including the homeotic genes of the bithorax complex.

55 he white gene and help activate genes of the bithorax complex.

56 ts other than evaluating their effect on the Bithorax-Complex (BXC) Abdominal B (Abd-B) mutant tuh-3.

57 al and, by genetic analysis, we identify the bithorax-complex genes and the ecdysone hormone as criti

58 cer of bithorax, a positive regulator of the Bithorax-Complex previously localized to the same geneti

59 gment identity genes of the Antennapedia and Bithorax complexes.

60 s of high EGFR signalling activity depend on bithorax gene function and that they account for the mai

61 and temporal expression of the Antennapedia-bithorax homeotic genes determining the fruit fly's body

62 differential sensitivity to the induction of bithorax phenocopies by ether vapor.

63 tor and the DNA sequence from the Drosophila bithorax region were also analyzed.