ライフサイエンスコーパス: blastoderm

1 om that of Drosophila hunchback in the early blastoderm.

2 e cell shape changes that further expand the blastoderm.

3 terior-posterior axis via subdivision of the blastoderm.

4 dy plan is proportionally represented on the blastoderm.

5 not independent processes in the Drosophila blastoderm.

6 on of Cdk1 waves in the Drosophila syncytial blastoderm.

7 s distributed cytoplasmically throughout the blastoderm.

8 mall number of giant nuclei in the syncytial blastoderm.

9 earlier defect: a failure to form a cellular blastoderm.

10 clear cycle 7, two cycles prior to syncytial blastoderm.

11 at accumulate in the same region during late blastoderm.

12 ffecting ubiquitously expressed genes in the blastoderm.

13 s communication between the two sides of the blastoderm.

14 r duplicated gsc expression in the overlying blastoderm.

15 uclei located at the cortex of the syncytial blastoderm.

16 ation is activated at cellularization of the blastoderm.

17 red for the cellularization of the syncytial blastoderm.

18 ive ectodermal and mesodermal regions of the blastoderm.

19 wedge-shaped cap at the leading edge of the blastoderm.

20 ng the transition from syncytial to cellular blastoderm.

21 ickening in the germ ring of the mid-epiboly blastoderm.

22 displaced forward to the leading edge of the blastoderm.

23 peripheral positions around the chick early blastoderm.

24 mulates on the ventral side of the syncytial blastoderm.

25 axis defined by the starting location of the blastoderm.

26 ping layer cells, the outermost cells of the blastoderm.

27 the growth zone but not those defined in the blastoderm.

28 e to the egg periphery to generate a uniform blastoderm.

29 metry of circular wounds punched through the blastoderm.

30 ne the serosa anlage of Episyrphus to dorsal blastoderm.

31 At cellular blastoderm, 25-50% of genes whose transcription can be m

32 At the end of blastoderm, a broad dorsal domain of weak SMAD response

33 TAG had been implicated in this pre-cellular blastoderm activation of sex-determination genes.

34 ells, a cluster of cells located outside the blastoderm, adjacent to the notochord domain.

35 ein gradient that functions in the syncytial blastoderm after 9-10 nuclear divisions.

36 d QCE-6 cells were incorporated within these blastoderm aggregate cultures.

37 Of-zen is also expressed in the blastoderm, although this early expression shows no appa

38 in which Hox domains clonally inherited from blastoderm ancestors are modified by diffusible signals

39 here in the double mutants, for cells of the blastoderm and for rare cells of the gastrula that invol

40 e co-SMAD Medea requires a BMP signal during blastoderm and gastrula stages.

41 sent a model in which patterning in both the blastoderm and germband of the beetle Tribolium castaneu

42 n a gap-like domain in the thorax during the blastoderm and germband stages of embryogenesis.

43 Here, we show that segmentation at both blastoderm and germband stages of Tribolium is based on

44 and intermediate germband insects spans both blastoderm and germband-derived segments.

45 both pseudocleavage furrows at the syncytial blastoderm and in the cleavage furrows during the cellul

46 wo phases, first in a gap-like domain in the blastoderm and later in the posterior growth zone during

47 repressor of epcam in the deep cells of the blastoderm and may contribute to control of epithelial i

48 ssion of this gene peaks around the cellular blastoderm and not in any later developmental stages.

49 ial nuclear layer that underlies the forming blastoderm and remains in continuity with the yolk.

50 broad zen expression domain in the syncytial blastoderm and the complete absence of postgastrular zen

51 The Drosophila blastoderm and the vertebrate neural tube are archetypal

52 ing of pseudoelastic plates representing the blastoderm and vitelline membrane.

53 arise in a nonelongating tissue (called the "blastoderm"), and posterior fates arise in an elongating

54 organism: a Drosophila-like mechanism in the blastoderm, and a vertebrate-like mechanism in the germb

55 ipe regulatory region generates 7 stripes at blastoderm, and later 14 stripes that persist throughout

56 An array of CRMs that generate 7 stripes at blastoderm, and later 14 stripes, surround slp1.

57 s, a number of anterior segments form in the blastoderm, and the remaining segments form sequentially

58 round the cortical nuclei to form a cellular blastoderm, and zygotic gene expression is first require

59 embryos, patchy loss of nuclei in syncytial blastoderms, and cuticular pattern defects in late-stage

60 that pseudocleavage furrows in the syncytial blastoderm are abnormal but not completely disrupted.

61 CC progenitors segregate from the blastoderm as part of the anterior lip of the ventral fu

62 revealed that Cx43 is present throughout the blastoderm at Hamburger-Hamilton stage 2-3, prior to kno

63 st become apparent during "doming," when the blastoderm begins to spread over the yolk sac, a process

64 other phenotypic class forms a rather normal blastoderm, but shows abnormalities in proliferation and

65 r K10, and anteroposterior patterning of the blastoderm by tuning the transcriptional repressor Tramt

66 these cells were cultured as a component of blastoderm cell aggregates, they differentiated into ful

67 within stage 3 or stage 4, but not stage 5, blastoderm cell aggregates.

68 n these cells were incorporated into stage 5 blastoderm cell aggregates.

69 lk syncytial layer) and (ii) differentiating blastoderm cells (each surrounded by a plasma membrane).

70 These results suggest that blastoderm cells located immediately anterior to the pos

71 on patterns that were exhibited by QCE-6 and blastoderm cells suggest that expression of differentiat

72 ocalization of a signal to the basal side of blastoderm cells that is needed later in the posterior m

73 sc where it continued to be localized to the blastoderm cells through cleavage, gastrulation, and lat

74 The cell phenotypes expressed by the blastoderm cells were dependent upon the age of the blas

75 phenotypes using aggregate cultures of avian blastoderm cells, which replicated mesodermal cell diver

76 erm cells were dependent upon the age of the blastoderm cells, with Hamburger-Hamilton stage 3 or 4 c

77 was in accordance with that displayed by the blastoderm cells.

78 ntial fates of marked anterior and posterior blastoderm cells.

79 formly covers the apical surface of cellular blastoderm cells.

80 The Drosophila MBT is marked by blastoderm cellularization and follows 13 cleavage-stage

81 s terminate, transcription increases and the blastoderm cellularizes.

82 er additional known and many candidate early blastoderm CRMs.

83 In post-blastoderm cycles that included a G2 phase, we found tha

84 During the maternally regulated syncytial blastoderm cycles, deleting S phase shortened interphase

85 during the transition from preblastoderm to blastoderm cycles.

86 djust gene activity to a variety of dipteran blastoderm cytoarchitectures.

87 rt a model in which weak BMP activity during blastoderm defines the boundary between ventral neurogen

88 sults show that Kruppel is required for both blastoderm-derived and germband-derived segments and ind

89 ent formative mechanisms may be operating in blastoderm-derived and germband-derived segments.

90 a set of genes involved in Drosophila early blastoderm development and using phylogenetic comparison

91 ey are in Drosophila, shifting anteriorly as blastoderm development proceeds.

92 n of cVg1 protein in the marginal zone chick blastoderms directs the formation of a secondary primiti

93 Our results imply that the formation of the blastoderm disc involves the aggregation of cells at the

94 eavage furrow formation during the syncytial blastoderm divisions.

95 generally believed to be established in pre-blastoderm Drosophila embryos by the diffusion of Bcd pr

96 lopment of a cell-free system from syncytial blastoderm Drosophila embryos that recapitulates many of

97 In syncytial blastoderm Drosophila embryos, actin caps assemble durin

98 In post-blastoderm Drosophila embryos, zygotic expression of the

99 assive mechanical properties of the cellular blastoderm during gastrulation.

100 slight thickening at the leading edge of the blastoderm during the formation of the germ ring, is one

101 rm a gradient in the nuclei of the syncytial blastoderm embryo after fertilization [1-3].

102 are initially expressed at both poles of the blastoderm embryo and in a single cephalic stripe.

103 egmental pattern in the Drosophila syncytial blastoderm embryo depends on pair-rule transcriptional r

104 xpression of btd in the anterior half of the blastoderm embryo directed by the hunchback proximal pro

105 Cellularisation of the Drosophila syncytial blastoderm embryo into the polarised blastoderm epitheli

106 ral polarity within the Drosophila syncytial blastoderm embryo is determined by the maternally encode

107 of sloppy-paired-1 (slp1) in the Drosophila blastoderm embryo make this system an attractive model f

108 Runt-dependent regulation in the Drosophila blastoderm embryo relies on unique, target-gene-specific

109 terning the dorsal surface of the Drosophila blastoderm embryo requires Decapentaplegic (Dpp) and Scr

110 cific sex-determining gene Sex-lethal in the blastoderm embryo requires runt activity.

111 furrow membranes in the syncytial Drosophila blastoderm embryo show rapid extension and retraction re

112 ys a local role in the lateral region of the blastoderm embryo to oppose Dpp activity in the neuroect

113 In the syncytial blastoderm embryo, activation of Tor triggers the Ras/Ra

114 In the syncytial blastoderm embryo, GFP-Pav-KLP cyclically associates wit

115 In the Drosophila blastoderm embryo, staining with antibodies against the

116 ontexts of both the Drosophila ovary and the blastoderm embryo, suggesting a conserved recognition me

117 capentaplegic and zerknullt in the syncytial blastoderm embryo, they are able to pattern the dorsoven

118 ssion consists of seven broad stripes in the blastoderm embryo, while late expression, which occurs a

119 encoded by the segmentation gene runt in the blastoderm embryo.

120 of gap and pair-rule genes in the Drosophila blastoderm embryo.

121 ssed and widely distributed in the syncytial blastoderm embryo.

122 he maternal Bicoid morphogen gradient in the blastoderm embryo.

123 mprising the neuroectoderm of the Drosophila blastoderm embryo.

124 g functions as a diffusible morphogen in the blastoderm embryo.

125 e Decapentaplegic (Dpp) pathway in the early blastoderm embryo.

126 s over six time points for every cell of the blastoderm embryo.

127 ise the first set of miRNAs activated in the blastoderm embryo.

128 erior and terminal patterning systems in the blastoderm embryo.

129 an evolutionary dynamic enhancer in the post-blastoderm embryo.

130 ortex are crucial for cellularization of the blastoderm embryo.

131 paB, patterns the dorsal-ventral axis in the blastoderm embryo.

132 the sensitivity of analysis of pre-syncytial blastoderm embryos and precluded studies of oocytes afte

133 mediates efficient repression in Drosophila blastoderm embryos and that repression by GscR requires

134 c regions bound at high levels in Drosophila blastoderm embryos are known or probable functional targ

135 B antibody injection into precellularization blastoderm embryos causes developmental arrest and the f

136 also show that expressing HairyAct in early blastoderm embryos causes ectopic Sex-lethal expression

137 The delay of mitosis in post-blastoderm embryos is due primarily to inhibitory phosph

138 In blastoderm embryos of both species, BMP activity peaked

139 xt, we examined the effect of X-rays on post-blastoderm embryos of Drosophila melanogaster.

140 Ftz/Ftz-F1 activate Sulf1 expression in blastoderm embryos via composite binding sites.

141 a that removes damaged nuclei from syncytial blastoderm embryos via DNA damage checkpoint kinase-medi

142 l pattern formation was simulated in virtual blastoderm embryos with small artificial genomes.

143 Following injection into pre-blastoderm embryos, 20-40% of fertile survivors produced

144 o analyze stage 14 oocytes and pre-syncytial blastoderm embryos, and found that stage 14 oocytes make

145 -transported with, localizing transcripts in blastoderm embryos, and that interfering with the activi

146 image-based data from hundreds of Drosophila blastoderm embryos, each costained for a reference gene

147 ified anti-KLP67A antisera are used to stain blastoderm embryos, mitochondria in the region of the sp

148 tein resides in the endoplasmic reticulum of blastoderm embryos, suggesting a role in the trafficking

149 ing the cortical nuclear cycles of syncytial blastoderm embryos, which lack gap phases.

150 fluorescently labelled mRNAs into syncytial blastoderm embryos.

151 itive nuclear protein import assay in living blastoderm embryos.

152 oocyte and apical transcript localization in blastoderm embryos.

153 ) stripe 3+7 enhancer (eve3+7) in Drosophila blastoderm embryos.

154 process for droplet trafficking dynamics in blastoderm embryos.

155 the left or the right lateral halves of the blastoderm, embryos are incapable of patterning normal l

156 esoderm-type Delta trafficking in the entire blastoderm epithelium and an expansion of mesoectoderm g

157 ncytial blastoderm embryo into the polarised blastoderm epithelium provides an excellent model with w

158 individual cells to the invagination of the blastoderm epithelium.

159 critical for the stability of the polarized blastoderm epithelium.

160 At blastoderm, Eve is expressed in 7 stripes that restrict

161 at epithelial surface cells not only trigger blastoderm expansion by reducing tissue surface tension,

162 Activation of nodal signaling in blastoderm explants shows that the requirement for mis f

163 of the link (CG13333) gene, as well as link blastoderm expression.

164 tion and morphogenetic cell behaviors during blastoderm formation and differentiation, germband conde

165 he timing of cellularization with respect to blastoderm formation in an insect with extreme short-ger

166 mbryos lacking zld are defective in cellular blastoderm formation, and fail to activate many genes es

167 nsistent with a gap segmentation role during blastoderm formation, but huckebein (Calb-hkb) is not.

168 to the growing basal-lateral membrane during blastoderm formation, but Slam is not detected during la

169 of their arrival at the surface and prior to blastoderm formation, nuclei become surrounded by comple

170 egic (Dpp) signaling pathway during cellular blastoderm formation.

171 ation of embryonic epithelia during cellular blastoderm formation.

172 cells around the yolk, but only part of this blastoderm forms the embryonic rudiment.

173 trachea, but little is known about its post-blastoderm functions.

174 play an important role in the timing of pre-blastoderm gene expression.

175 raembryonic tissue that underlies the entire blastoderm, has been implicated in dorsal shield specifi

176 separates the 6,000 nuclei of the syncytial blastoderm into separate cells through the invagination

177 r-rule and HOX) that subdivide the syncytial blastoderm into sequentially finer-scale coordinates.

178 esults in a separation of the cleavage stage blastoderm into two halves that undergo separate develop

179 Formation of the Drosophila cellular blastoderm involves both membrane invagination and cytos

180 a related molecules, gata5 expression in the blastoderm is abolished, making these factors primary ca

181 htforward alternative in which the syncytial blastoderm is approximated by a periodic arrangement of

182 In Drosophila, the cleavage of the syncytial blastoderm is initiated by an actomyosin network at the

183 ed around individual nuclei in the syncytial blastoderm is likely to ensure that secretory organelles

184 , ventral specification within a dorsal half-blastoderm is not suppressed.

185 sophila melanogaster, but its thick columnar blastoderm is unusual among insects.

186 Lateral blastoderm isolates (LBIs) at the late gastrula/early ne

187 tterning the chick ectoderm, we used rostral blastoderm isolates (RBIs) as an assay, that is, rostral

188 Transverse blastoderm isolates containing non-specified, prospectiv

189 constitution of the notochord using cultured blastoderm isolates lacking Hensen's node and the primit

190 al induction and patterning using transverse blastoderm isolates obtained from gastrulating chick emb

191 es Hensen's node, when transplanted to other blastoderm isolates.

192 sterior marginal zone (PMZ), a region of the blastoderm known to contain the axial organizing activit

193 , and germband fates could be generated in a blastoderm-like morphology.

194 g, being expressed in both the ventrolateral blastoderm margin and also in the axial mesendoderm.

195 enes cyclops and squint are expressed at the blastoderm margin and are required for prechordal plate

196 hordal plate progenitors reside close to the blastoderm margin and express the homeobox gene goosecoi

197 These behaviours begin at the blastoderm margin and propagate in a gradient towards th

198 presumptive anterior neural ectoderm and the blastoderm margin at the late blastula.

199 ata suggest that both oep and ntl act in the blastoderm margin to specify mesendodermal cell fates.

200 all proportion of the cells initially at the blastoderm margin undergo ingression there, but most rec

201 actin and myosin immediately vegetal to the blastoderm margin via Ca(2+) reduction or treatment with

202 cides with gata5 in the cells closest to the blastoderm margin, then spreads to encompass the germ ri

203 resulted in cellular disorganization at the blastoderm margin.

204 loci of high calcium activity bordering the blastoderm margin.

205 2 are expressed during blastula stage in the blastoderm margin.

206 tortion of the embryo resulted in nonuniform blastoderm migration and realignment of the anterior-pos

207 found that local alterations in the rate of blastoderm migration correlated with the local geometry

208 lated as a mutation that dominantly prolongs blastoderm mitotic cycles in Drosophila, encodes a Droso

209 ment insertions in genes which slow down the blastoderm mitotic divisions.

210 nclude cellularization and patterning in the blastoderm, morphogenesis, and cell survival.

211 gle signaling source for LR pattern, but the blastoderm must be intact.

212 most genes that are transcribed pre-cellular blastoderm, not just those involved in sex determination

213 fusion coefficients throughout the syncytial blastoderm nuclear cycle phase of the early embryo.

214 ufficient for slp1 activation in all somatic blastoderm nuclei that do not express the Fushi tarazu (

215 Ftz is sufficient for slp1 repression in all blastoderm nuclei.

216 staneum, the embryos of which exhibit a thin blastoderm of cuboidal cells, like most insects.

217 ion, we still know very little about how the blastoderm of short and intermediate germband insects is

218 and species-specific microRNAs in the early blastoderm of T. castaneum is consistent with previous f

219 s necessary for cell movement throughout the blastoderm of the early embryo.

220 Epiboly, the spreading of the blastoderm over the large yolk cell, is the first morpho

221 Epiboly spreads and thins the blastoderm over the yolk cell during zebrafish gastrulat

222 cell rearrangements that spread the teleost blastoderm over the yolk.

223 d, runt and hairy are all expressed as early blastoderm pair-rule stripes and late-forming posterior

224 e of the six most highly bound regions drive blastoderm patterns of reporter transcription.

225 er cells, and dissociation of cells from the blastoderm, phenocopying e-cadherin mutants.

226 l torso response elements that mediate early blastoderm polar expression, we show that the complex br

227 d units of ER and Golgi across the syncytial blastoderm produced secretory products that were deliver

228 Finally, expression of Of'E75A in the blastoderm requires even-skipped, which is a gap gene in

229 ve abnormalities in epithelialization of the blastoderm, resulting in loss of the blastodermal cells'

230 sion and dispersal of yolk syncytial nuclei, blastoderm retraction, and death, effects highly similar

231 ient for normal development of the overlying blastoderm, revealing an involvement of extraembryonic s

232 ened interphase, and deletion of the last of blastoderm S phase (cycle 14) induced an extra synchrono

233 nteractions regulates virtually simultaneous blastoderm segmentation.

234 tion at 25A1,2, we have designated this gene blastoderm-specific gene 25A (bsg25A).

235 ion during epiboly, the process in which the blastoderm spreads over the yolk cell.

236 tes a sensitized non-lethal phenotype at the blastoderm stage (defined as six cycB phenotype).

237 tage, disappears rapidly during the cellular blastoderm stage and is not detected at any other point

238 this single mechanism functions in the early blastoderm stage and subsequently during germ-band elong

239 the anterior segments are formed during the blastoderm stage and the remaining posterior segments ar

240 ow that smaug mutants also disrupt syncytial blastoderm stage cell-cycle delays, DNA replication chec

241 o stripes of expression (stripes 3 and 7) in blastoderm stage Drosophila embryos.

242 nes, one stripe for each parasegment, in the blastoderm stage embryo.

243 verlapping domains in the head region of the blastoderm stage embryo.

244 ural analysis of Drosophila chromosome 2L in blastoderm stage embryos.

245 the layer of peripheral nuclei in syncytial blastoderm stage embryos.

246 razu (ftz) of Drosophila is expressed at the blastoderm stage in seven stripes that serve to define t

247 mined their domains of expression during the blastoderm stage of development, in relation to one anot

248 ned a gene expressed specifically during the blastoderm stage of Drosophila embryogenesis.

249 form levels throughout the embryo during the blastoderm stage of embryogenesis.

250 In blastoderm stage Presenilin mutants, Arm is aberrantly d

251 atory elements, including ones for syncytial blastoderm stage stripes 1 and 5, while a single element

252 ase, produced sharply defined stripes at the blastoderm stage that were coincident with eve stripe 2

253 el, we have ectopically expressed fog at the blastoderm stage using an inducible promoter.

254 axis, and all segments are patterned at the blastoderm stage, before gastrulation.

255 aximally expressed during the late syncytial blastoderm stage, disappears rapidly during the cellular

256 ciate with the male X chromosome as early as blastoderm stage, slightly earlier than the histone H4 i

257 ecified nearly simultaneously so that by the blastoderm stage, the entire body plan has been determin

258 sufficient for even skipped function at the blastoderm stage, while the homeodomain is sufficient to

259 only anterior segments are patterned at the blastoderm stage, with the remaining segments arising af

260 n anterior nuclei in the embryo at syncytial blastoderm stage, within 1.5-2.5 h after translation com

261 all of the body regions are specified by the blastoderm stage.

262 t anterior body regions are specified by the blastoderm stage.

263 nt but instead maintain repression after the blastoderm stage.

264 t at PS9, which shifts posteriorly after the blastoderm stage.

265 istently required throughout the rest of the blastoderm stage.

266 e traced these defects back to the syncytial blastoderm stage.

267 s but becomes depleted at the termini by the blastoderm stage.

268 ges to equivalent patterns at the end of the blastoderm stage.

269 rule gene even skipped (eve) at the cellular blastoderm stage.

270 l germ cells are specified from at least the blastoderm stage.

271 entrosomes in Drosophila embryos at cellular blastoderm stage.

272 efly with that of SxlPe during the syncytial blastoderm stage.

273 egulating spatial expression patterns in the blastoderm-stage Drosophila embryo.

274 ng neuregulin-1 hammerhead-type ribozymes to blastoderm-stage embryos leads to an embryonic lethal ph

275 as the embryo transits from preblastoderm to blastoderm stages and defines the onset of a checkpoint

276 Transcripts persist strongly during early blastoderm stages then fade dramatically by 3h of develo

277 At late blastoderm stages, none of the candidate genes we have t

278 rapid nuclear divisions before the syncytial blastoderm starts to cellularize.

279 features of eve expression: the seven major blastoderm stripes, minor stripe expression during germ

280 together with the requirement for an intact blastoderm, suggests that the path of communication thro

281 ave studied pattern formation in dorsal half-blastoderms that contain the entire shield region but on

282 ucing tissue surface tension, but also drive blastoderm thinning by inducing tissue contraction throu

283 the MBT to allow the formation of a cellular blastoderm through a special form of cytokinesis termed

284 We show that cells can leave the dorsal blastoderm to join the forerunners, suggesting that relo

285 In addition, other blastoderm transcription factors, comprising both activa

286 nce of the TAGteam sequences to pre-cellular blastoderm transcription was established through analysi

287 r of TAGteam sites retarded the onset of pre-blastoderm transcription, whereas increasing their numbe

288 Is) as an assay, that is, rostral regions of blastoderms transected at levels rostral to the node.

289 ial deep cells of the marginal region of the blastoderm undergo ingression.

290 ster do not participate in involution as the blastoderm undergoes epiboly.

291 II and microtubules in syncytial Drosophila blastoderms using drug treatments, time-lapse movies and

292 s, as Drosophila and Tribolium segment their blastoderms using the same genes but different mechanism

293 nterior-posterior fates are specified in the blastoderm versus the germband.

294 enes localise to the apical cytoplasm of the blastoderm via a selective dynein-based transport system

295 In Drosophila, all segments form in the blastoderm where morphogen gradients spanning the entire

296 mbryo are determined in the syncytium of the blastoderm, whereas the abdominal segments proliferated

297 ocleavage furrow formation in the Drosophila blastoderm with how the mitotic apparatus positions the

298 goes a transition from syncytial to cellular blastoderm with the de novo generation of a polarized ep

299 ed epiblast cells in the Stage XI-XIII chick blastoderms with GFP fusion proteins.