ライフサイエンスコーパス: blinking

1 fer from intermittent on/off light emission (blinking).

2 vertical meridian was 342 +/- 155 mum after blinking.

3 e goal of clarifying the role of charging in blinking.

4 inked normally or successfully inhibited eye blinking.

5 ide robust signals without photobleaching or blinking.

6 tracts to close the palpebral fissure during blinking.

7 he interfacial ET reactivity fluctuation and blinking.

8 nking, but it becomes altered during delayed blinking.

9 nt constraint on possible mechanisms for the blinking.

10 long-lasting change in eyelid asymmetry with blinking.

11 k population does not arise from millisecond blinking.

12 fluorophore interactions, as well as on-off blinking.

13 e measurements by accounting for fluorophore blinking.

14 e-aggregate emission characterized by strong blinking.

15 cence known as fluorescence intermittency or blinking.

16 oteins and overcounting owing to fluorophore blinking.

17 hip between charge trapping and fluorescence blinking.

18 s of single-dot emission intensity, known as blinking.

19 mission and the most complete suppression of blinking.

20 tinuously to track vertical movements during blinking.

21 Blinking 5 times facilitated such recovery in normal sub

22 fering from foreign body sensation, frequent blinking and bilateral inferior conjunctivochalasis was

23 Our Bayesian analysis of the blinking and bleaching (3B analysis) method models the e

24 Bayesian blinking and bleaching (3B) reconstruction reveals that

25 nifies the analysis of the localization from blinking and bleaching events.

26 Although blinking and characteristic emission patterns demonstrat

27 II electronic structures exhibit suppressed blinking and diminished nonradiative Auger recombination

28 e intervention of such processes, as well as blinking and kindling, in fluorescent proteins.

29 ing and oxidizing systems (ROXS) that reduce blinking and oxygen scavenging systems to reduce bleachi

30 both this multi-colour emission process, and blinking and photobleaching behaviours of single tetrapo

31 of these emitters are frequently degraded by blinking and photobleaching that arise from poorly passi

32 in their emission characteristics, including blinking and photobleaching that limit their utility and

33 unwanted photophysical properties, including blinking and photobleaching, which limit their overall e

34 om their limited photostability evidenced by blinking and photobleaching.

35 ein also uncovered surprises, especially the blinking and photoinduced recovery of emitters, which st

36 excited states are thus required to minimize blinking and sensitization of singlet oxygen.

37 han expected by chance, they inhibited their blinking and shifted visual fixation differentially with

38 re, we introduce a kinetic model to describe blinking and show that Dendra2 photobleaches three times

39 Although the frequent erratic blinking and substantial dark (never radiant) fractions

40 light harvesting by controlled fluorescence blinking and suggest that any contribution of the minor

41 gating the neural basis of human spontaneous blinking and suggest that the spinal trigeminal complex

42 ined: (1) eye closure times, (2) spontaneous blinking, and (3) spontaneous and eye closure-triggered

43 ng reconstruction to the detected stochastic blinking, and achieved a spatial resolution of at least

44 responsible for long-range photoluminescence blinking, and are also mobile.

45 ty, their brightness, long lifetime, lack of blinking, and chemical stability make nanoparticle based

46 hemical and mechanical means evokes tearing, blinking, and pain.

47 methods is complicated by photodegradation, blinking, and the presence of natural organic material a

48 t energy transfer, anomalous single particle blinking, and twinkling phenomena associated with polaro

49 s methods used to measure single nanocrystal blinking are introduced.

50 We find that two distinct types of blinking are possible: conventional (A-type) blinking du

51 rmittency in nanocrystal emission, that is, 'blinking', arising from the escape of either one or both

52 Called bleaching/blinking assisted localization microscopy (BaLM), the te

53 zation precision in some other bleaching- or blinking-assisted techniques.

54 try, these processes may underlie changes in blinking associated with facial palsy and may play a rol

55 -green fluorescence protein (GFP) revealed a blinking behavior similar to that reported for GFP-clath

56 mic diameter less than 11.0 nm), and reduced blinking behavior.

57 ed by suppression of both photobleaching and blinking behavior.

58 long standing theories on photoluminescence blinking behavior.

59 al days, and they exhibit markedly different blinking behavior; >20% of the g-NQDs do not blink, whil

60 hnique relies on the intrinsic bleaching and blinking behaviors characteristic of all commonly used f

61 pes of defect-induced photoluminescence (PL) blinking behaviors observed in single epitaxial InGaAs q

62 and Dendra2-T69A, we completely swapped the blinking behaviors of mEos2 and Dendra2, two popular PCF

63 ates, resulting in widely different apparent blinking behaviors that largely modulate the efficiency

64 nce trajectories show strong fluctuation and blinking between bright and dark states.

65 link entrainment, a temporal coordination of blinking between social partners engaged in dyadic inter

66 ically balanced and consistent during normal blinking, but it becomes altered during delayed blinking

67 have extended the measurement of quantum-dot blinking by characterizing fluctuations in the fluoresce

68 In contrast to fluorescent dyes that show blinking characteristics due to reversible photobleachin

69 stimuli based on kinematic analyses of mouse blinking consistently suppress SbC-RGC spiking.

70 pparent/observed affinity to account for the blinking contribution.

71 t largely modulate the efficiency of current blinking correction procedures.

72 ults suggest that in macaques, as in humans, blinking depends not only on the physiological imperativ

73 tuations in the emission lifetimes (lifetime blinking), despite stable nonblinking emission intensity

74 age correlation spectroscopy of quantum dots blinking detects T cell receptor clusters on a scale of

75 NPs exhibit no on/off emission behavior, or "blinking," down to the millisecond timescale, and no los

76 atic oxygen-scavenging system eliminates Cy5 blinking, dramatically reduces photobleaching and improv

77 blinking are possible: conventional (A-type) blinking due to charging and discharging of the nanocrys

78 Here we show that unexpected blinking during graphene oxide-to-reduced graphene oxide

79 high blinking statistics and an appropriate blinking duty cycle on imaging quality, and developed a

80 Moreover, typical toddlers inhibited their blinking earlier than toddlers with ASD, indicating acti

81 onstrate effectively complete suppression of blinking even for long observation times of ~1 h.

82 ividual dark and bright qdots and to observe blinking events as qdots freely diffused in aqueous solu

83 show that the distribution of the number of blinking events assumes a universal functional form, ind

84 ecular counting based on the distribution of blinking events from a single fluorophore.

85 increase both the frequency and duration of blinking events of Cy5, an effect that scales with reduc

86 detailed mechanism is not fully understood, blinking experiments are found to provide direct evidenc

87 An overview of blinking experiments used to probe specific mechanisms f

88 re fluorescence from rapid, sub-millisecond "blinking" fluctuations (fluid polymer environment) to co

89 We found no evidence of blinking (fluorescence intermittency) in solution on nan

90 ntly tagging single molecules with multiple, blinking fluorophores, the accuracy of the technique can

91 We monitored spontaneous blinking for 55 min periods in normal conditions and aft

92 ntrinsic stochastic fluorescence emission or blinking from unstained polymers and performed spatial-t

93 Studies of the blink reflex and spontaneous blinking have provided useful neurophysiologic informati

94 single-dot emission intermittency (known as blinking) have been recognized as universal requirements

95 epletion, more channels start blinking, with blinking heights increasing over time, suggestive of slo

96 The temporal synchrony of blinking, however, increased in response to segments dep

97 ients with blepharospasm (BSP) and increased blinking (IB).

98 in charged nanocrystals, with successful non-blinking implementations demonstrated in CdSe-CdS core-t

99 ve (dark) states that result in fluorescence blinking in a variety of timescales.

100 This study therefore examined blinking in freely-moving peacocks (Pavo cristatus) to d

101 and single-molecule microscopy to show that blinking in mEos2 and Dendra2 is largely controlled by t

102 responsible for the regulation of normal eye-blinking in mice.

103 Fluorescence blinking in nanocrystal quantum dots is known to exhibit

104 -domain (TD)-OCT before and while preventing blinking in order to produce a wide variety of signal st

105 e additional applicability toward explaining blinking in other systems, a problem of current interest

106 blink amplitude and the rate of spontaneous blinking in rodents.

107 ibited a significant increase in spontaneous blinking in the light relative to the blink rate in dark

108 administration of a TRPM8 antagonist reduced blinking in wild-type mice.

109 that takes advantage of the intermittency ("blinking") in the fluorescence of quantum dots (QDs) to

110 on of a semi-involuntary motor behavior, eye blinking, in children and adults with Tourette syndrome

111 ightness per particle, saturation intensity, blinking (intermittency), hydrodynamic radius, and prope

112 emporal fluctuations (caused by fluorescence blinking/intermittency) recorded in a sequence of images

113 f the normal pattern of episodes of frequent blinking interspersed with intervals having few blinks.

114 ugh which the basal ganglia modulates reflex blinking is (1) the substantia nigra pars reticulata inh

115 Because of its simplicity, blinking is a prominent model system in analysis of adap

116 Blinking is an effective compensatory mechanism to disti

117 Rapid blinking is associated with worse ocular surface disease

118 The observed single-molecule fast blinking is attributed to conversions between the fluore

119 stent with the predictions of models wherein blinking is controlled by diffusion of the energies of e

120 Fluorescence intermittency or blinking is observed in nearly all nanoscale fluorophore

121 Although spontaneous blinking is one of the most frequent human movements, li

122 trast with previous observations, single-dot blinking is significantly suppressed with only a relativ

123 After lid blinking, it took a longer time (2.2 +/- 1.1 second) to

124 roscopy (FCS) can resolve the intrinsic fast-blinking kinetics (FBKs) of fluorescent molecules that o

125 f the mechanisms responsible for nanocrystal blinking kinetics as well as core-shell engineering effo

126 nts over existing dyes, and the nonpower law blinking kinetics suggest that these very small species

127 ts, the volunteers were asked to fixate on a blinking LED.

128 uctor nanostructures could share the same PL blinking mechanism.

129 Both blinking mechanisms can be electrochemically controlled

130 The development of numerous blinking mechanisms is reviewed, as is the physical natu

131 te over a decade of research, completely non-blinking nanocrystals have not been synthesized and an u

132 ntinuous output of single photons, these non-blinking nanocrystals may enable substantial advances in

133 Here we show that blinking nanorods (NRs) interact with each other in a cl

134 s kept constant during blinks, we found that blinking nevertheless suppressed activity in visual cort

135 ymer environment) to completely "on" with no blinking observed (molecules adsorbed to a rigid bare gl

136 Incomplete blinking occurred significantly less often in women (51.

137 While quantum dot blinking occurs during these measurements, we describe a

138 tep with a slow transition that accounts for blinking of 527 nm emission at the single molecule level

139 Our approach allowed us to monitor fast blinking of an organic dye, the dissociation kinetics of

140 Photoinduced blinking of Cy5 has hampered many previous investigation

141 Simple light-induced blinking of eYFP and collisional flux onto the cell surf

142 Photobleaching and blinking of fluorophores pose fundamental limitations on

143 plasmon resonance effects result in optical blinking of GNPs at a size-dependent wavelength.

144 istics due to reversible photobleaching, the blinking of GNPs seems to be stable for long periods of

145 The intrinsic blinking of photoactivatable fluorescent proteins mEos2

146 f qdots localized in dilute agarose gel, the blinking of qdots was measured across five orders of mag

147 However, the stochastic blinking of single fluorophores can introduce large unce

148 ecules is their photo-reactivity, leading to blinking of the fluorescence signal, and eventually to i

149 rora, a spectacular emission that appears as blinking of the upper atmosphere in the polar regions, i

150 alization micro-scopy studies of fluorophore blinking offer a promising route to probe oligomeric sta

151 -molecule emission rates, and essentially no blinking on experimentally relevant time scales (0.1 to

152 a promising tool for studying the impact of blinking on tear dynamics.

153 graphy (OCT) was used to study the impact of blinking on tear dynamics.

154 from purely mechanical or optical effects of blinking on visual input by combining pupil-independent

155 go repeated cycles of fluorescent emission ('blinking') on a timescale of several seconds-behaviour t

156 meniscus did not change significantly during blinking or during the open-eye period.

157 been synthesized and an understanding of the blinking phenomenon remains elusive.

158 uding suppressed fluorescence intermittency (blinking), photobleaching, and nonradiative Auger recomb

159 robenzyl alcohol, act to favorably attenuate blinking, photobleaching, and influence the rate of phot

160 ls that individually exhibit continuous, non-blinking photoluminescence.

161 al clustering analysis that leverages on the blinking photophysics of specific organic dyes showed th

162 Blinking, previously seen in confined zero- and one-dime

163 ts but did increase the detected fraction of blinking qdots, suggesting that the dark population does

164 this method, time-lapse sequences of single blinking QDs were acquired and the centroids of the poin

165 Images of the blinking QDs were then overlapped in software, pixel by

166 Novel non-blinking quantum dots (NBQDs) were utilized in three-dim

167 Photoluminescence blinking--random switching between states of high (ON) a

168 ficantly (P = .02) greater lagophthalmos and blinking rate (P = .04).

169 A significantly higher blinking rate and lagophthalmos were found in subjects w

170 The blinking rate was also significantly greater in subjects

171 The blinking rate, eye closure, heart rate, alpha and beta b

172 Blinking rate, lagophthalmos, eyelid laxity, MGD, Schirm

173 rial infections impairs tear production, the blinking reflex, and epithelial wound healing, resulting

174 Spontaneous eye blinking serves a critical physiological function, but i

175 During normal and delayed blinking sessions, the tear film thickness increased sig

176 As photoluminescence blinking severely limits the usefulness of nanocrystals

177 t is an intrinsic consequence of quantum dot blinking statistical ageing.

178 ned the effects of a high photon count, high blinking statistics and an appropriate blinking duty cyc

179 n a cluster, and the interactions affect the blinking statistics.

180 o determine molecule counts from fluorophore blinking statistics.

181 -down modulation of visual processing during blinking, suggesting a possible mechanism by which blink

182 g suppression, such that larger cores afford blinking-suppressed behavior at relatively thinner shell

183 ume (~750 nm(3)) that is required to observe blinking suppression and that this particle volume corre

184 anocrystals; however, the physics underlying blinking suppression remains unclear.

185 orrelation between g-NQD particle volume and blinking suppression, such that larger cores afford blin

186 hereas ZnSe/CdS gQDs show characteristic gQD blinking suppression, though only if shelling is accompa

187 thicker shells to realize the same level of blinking suppression.

188 Plasmonic hotspots generate a blinking Surface Enhanced Raman Spectroscopy (SERS) effe

189 shape is diagnostic of defects that control blinking, surface carrier dynamics, and other important

190 d by significant fluorescence intermittency (blinking) that hinders applications as single-photon lig

191 In the first type of PL blinking, the "off" period is caused by the trapping of

192 or the "off" period in the second type of PL blinking, the electrons relax from the first excited sta

193 vestigate asymmetry in eyelid movements with blinking, the stability of the asymmetry, and its modifi

194 We attribute B-type blinking to charge fluctuations in the electron-acceptin

195 We developed a rat model of spontaneous blinking to identify and better characterize the spontan

196 nd photoswitching, (iii) phototoxicity, (iv) blinking, (v) permanent bleaching, and (vi) formation of

197 ilitate future engineering of bright and low-blinking variants suitable for PALM.

198 an rats, the temporal pattern of spontaneous blinking was qualitatively similar for both species.

199 Signal loss because of blinking was the most common artifact on 3D scans (optic

200 The tear meniscus height, with and without blinking, was recorded and calculated by video meniscome

201 with corrections for submillisecond acceptor blinking, we show that it is possible to obtain structur

202 lower tear menisci during normal and delayed blinking were obtained from OCT images using custom soft

203 d with enhanced mutual gaze and empathic eye blinking, whereas indifference or malevolence was associ

204 d by large intensity fluctuations, known as 'blinking', whereby their photoluminescence turns 'on' an

205 sistent temporal organization to spontaneous blinking with a median 750 s period that was independent

206 hough there are changes in the kinematics of blinking with age, such changes do not necessarily predi

207 Upon cAMP depletion, more channels start blinking, with blinking heights increasing over time, su

208 surface showed fluorescence fluctuations and blinking, with time constants distributed from milliseco