ライフサイエンスコーパス: blocking

1 -selective antagonist KW-6002, inducing full blocking.

2 Notably, blocking 12-HETE production inhibits IR-induced liver dy

3 We have also provided proof of concept that blocking 12-HETE production is a promising strategy for

4 rier to spin reversal (770.8 K) and magnetic blocking (14 K).

5 structure shows that, rather than sterically blocking 40S translational active sites, the associated

6 hese results, we investigated the effects of blocking 5-HT and beta-adrenoceptor transmission in DH o

7 3 expression in response to Activin, thereby blocking a direct route to embryonic cardiac mesoderm fo

8 ytokine production was inhibited by a HLA-DR blocking Ab.

9 Blocking aberrant signaling from endosomes or reducing B

10 rformed on animals of both sexes showed that blocking Abeta function, by using anti-murine Abeta anti

11 Therapeutic administration of anti-MSLN-blocking Abs attenuated BDL-induced fibrosis in WT mice.

12 sessment of risks in patients receiving IL-1 blocking Abs for treatment of chronic inflammatory disor

13 tious particles and the stochastic minefield blocking access to host DNA.

14 Strikingly, mutants blocking acetylation exacerbate alpha-synuclein toxicity

15 data demonstrate that post-AIT sera with IgE-blocking activity ameliorate allergic airway inflammatio

16 ounds with dual therapeutic and transmission-blocking activity are desired as high-value partners for

17 d is 10(-5) or higher although they may show blocking activity in the TEV assay.

18 Molecular modeling suggests that this blocking activity may originate from binding of the pept

19 We confirm in vitro transmission-blocking activity of four of the six selected molecules

20 The IgE-blocking activity of post-AIT sera was assessed in vitro

21 cular mechanism of its antibody transmission-blocking activity.

22 , sensitization-induced IgG did not show IgE-blocking activity.

23 Post-AIT sera exerted IgE-blocking activity.

24 ferentially activate efferent pathways while blocking afferent pathways.

25 4 (23%) lacked BSACI compliant neuromuscular blocking agent (NMBA) panels and 17/44 (39%) lacked a NA

26 our data suggest that therapeutic CD40-CD40L blocking agents may prove efficacious not only in early

27 ffects of various gene deletions or chemical blocking agents were tested by investigating the express

28 n-pretreated wild-type mice, these compounds blocking alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropi

29 states near the Dirac point leads to contact blocking and a gate-dependent modulation of the photocur

30 CD13 and VLA-4 blocking and activating Abs were used in flow-based adhe

31 Using receptor-blocking antibodies and activation peptides, we determin

32 Therapeutic strategies using anti-PD-1-blocking antibodies reported unparalleled effectiveness

33 Blocking antibodies were used to dissect the role of Tol

34 n cancer therapy to a similar degree as PD-1 blocking antibodies, offering a next-generation approach

35 nizing Siglec-8 in combination with integrin blocking antibodies, pharmacologic inhibitors, phosphopr

36 n cancer therapy to a similar degree as PD-1-blocking antibodies.Significance: These findings show ho

37 On the other hand, the persistence of IgE blocking antibody 1 year after discontinuation might be

38 IFN-gamma blocking antibody administered to Sphk2(-/-) mice or del

39 A blocking antibody against (ILFA1), disrupting the lympho

40 Finally, a blocking antibody against beta8 inhibited immunosuppress

41 We also show that a blocking antibody antigen-binding fragment binds to the

42 eutic effect of the humanized anti-Jagged1/2-blocking antibody CTX014 on MDSC-mediated T-cell suppres

43 ceptor protected mice after treatment with a blocking antibody directed against PD-1.

44 ogrammed cell death protein 1 (PD-1) pathway-blocking antibody nivolumab has shown substantial therap

45 ment of ovarian tumor-bearing mice with PD-1 blocking antibody resulted in an increase in IL10 levels

46 of multiple sclerosis (MS), we administered blocking antibody to CLEC12A that significantly ameliora

47 tion in AKI, we utilized a specific function-blocking antibody to inhibit alphavbeta5 in a rat model

48 nd safety of pembrolizumab, a humanized PD-1-blocking antibody, at a dose of 200 mg every 3 weeks in

49 n of VE-cadherin clustering at AJs (function-blocking antibody, FBA) inhibited dilatation to acetylch

50 in a manner that was abrogated by anti-PD-L1 blocking antibody.

51 complex with two distinct antagonists and a blocking antibody.

52 nd collaborative functions of M36 and M45 in blocking apoptotic and necroptotic cell death responses.

53 en together, the data indicate that, besides blocking AR, antiandrogens modify androgen signaling in

54 role in MPTP/MPP(+)-induced neurotoxicity by blocking ASK1-mediated signaling.

55 the ELISA but little reactivity by the HBGA blocking assay between GII.4 norovirus and the new GII.1

56 LISA) and a histo-blood group antigen (HBGA) blocking assay using sera from GII.4 and the GII.17 vari

57 vity had been observed in a similar receptor-blocking assay.

58 analysis followed by inhibitor and antibody-blocking assays revealed that the arthropod HSP70-like m

59 Using rotavirus binding and blocking assays, this study elucidated how RRV VP4 prote

60 At room temperature, blocking ATP hydrolysis effectively abolished slow endoc

61 r transplantation and if it was effective in blocking atrioventricular nodal conduction in these pati

62 In Drosophila, we demonstrate that blocking autophagy at any step of the pathway enhances R

63 Blocking autophagy partially rescued PEX1/pex1-3 defects

64 Blocking BACE-1 action, on the other hand, blocks Egr-1-

65 AR S81 is also phosphorylated by CDK1, and blocking basal CDK1-mediated S81 phosphorylation markedl

66 aptamers with dual activity for effectively blocking both AMPA and kainate receptors.

67 n in CAF-facilitated HNSCC progression after blocking CAF autophagy.

68 T patients, showing markedly higher allergen-blocking capacity (P < .001).

69 rvation that prepandemic sera possess robust blocking capacity for viruses identified decades later s

70 Removal of blocking cargo also restores cell morphology and attenua

71 s, whereas CCR5 ligands inhibit infection by blocking CCR5 engagement with HIV gp120.

72 Blocking CD84 in vitro and in vivo disrupt the interacti

73 Blocking Cdk5 action blocks Egr-1-induced tau phosphoryl

74 te to enact tumor suppression, the former by blocking cell proliferation and the latter by recruiting

75 n of histone H3 at K36 (H3K36), subsequently blocking cellular differentiation and promoting oncogene

76 ts GR interaction with CHD9 and BRM, thereby blocking chromatin remodeling and robust GR binding at G

77 which all inhibited LGR5 internalization by blocking clathrin-mediated endocytosis.

78 Blocking complex glycosylation of Env affected V2 bnAb r

79 fide linkage indirectly affects signaling by blocking conformational changes induced by weak integrin

80 Blocking contractility increases nuclear circularity in

81 Enhancing activity by focally blocking cortical GABAergic inhibition had a similar rel

82 of afferent terminal responsiveness, whereas blocking CP-AMPARs protects terminals from excitotoxic s

83 lation and swelling that can be prevented by blocking CP-AMPARs.

84 Calcium channel blocking curtailed the enhanced insulin response due to

85 Blocking CX3CR1 or nitric oxide production during G-CSF

86 in fibroblasts of human gingival wounds, and blocking Cx43 function in cultured human gingival fibrob

87 amine transients was further increased after blocking D2-autoreceptors.

88 ble for the cleavage of NEDD8 from CRLs, and blocking deconjugation of NEDD8 traps the CRLs in a hype

89 normal pattern of embryonic gene expression blocking development at the morula-blastocyst transition

90 values for (S)-orteronel were identical for blocking DHEA formation from pregnenolone and for 17alph

91 l cells reveal that a slow AHP is reduced by blocking different components of the CaV1.3-densin-CaMKI

92 d ketamine are NMDA receptor (NMDAR) channel-blocking drugs with divergent clinical effects.

93 or state-dependent binding of sodium channel-blocking drugs.

94 induced DNA double-strand break (DSB) sites, blocking DSB repair, which led to DSB accumulation, DNA

95 HD and suggests potential therapies based on blocking early binding events involving the terminal add

96 cently reported positive rate-dependent IKur-blocking effects on human atrial APs, and provide insigh

97 exes, and (3) electrode morphology-dependent blocking effects.

98 Blocking either classical calpain or atypical small opti

99 In contrast, blocking either PKM Apl II or PKM Apl III in L7, or PKM

100 Manipulation of extracellular glycine by blocking either, or both, the glial and neuronal glycine

101 Blocking electroneutral Na(+) movement is predicted to b

102 covered by applying an artificial INaP after blocking endogenous INaP with tetrodotoxin.

103 ke, food-motivation, and food-seeking, while blocking endogenous PVT GLP-1R signaling increased meal

104 sequence is used to detect ligand binding as blocking events during DNA unzipping, allowing determina

105 In the presence of tRNA, blocking events of single-channel currents through the p

106 Blocking externalized PS or suppressing TMEM16F inhibite

107 , brefeldin A, diphenyleneiodonium, DNase or blocking F(ab')2 fragments to CD16, CD18, CD32 and CD64.

108 Phleum pratense-specific IgG4 and IgE-blocking factor increased from baseline in both children

109 Blocking FAP ciliation also enhanced myofiber regenerati

110 Blocking FGF2b's synthesis and FGFR1 function reduced LM

111 With the addition of a blue light-blocking filter in normoxia, a significant increase in a

112 chondrial fission during osmotic stress, but blocking fission did not affect AMPK activation.

113 Non-specific binding was prevented by blocking free spaces on surface via starting block phosp

114 depression of dendritic IPSCs isolated after blocking GABAa receptor on the soma.

115 as immunogens in rabbits, and found that the blocking glycans eliminated the induction of tier-1 NAbs

116 ort a way to selectively kill Trypanosoma by blocking glycosomal/peroxisomal import that depends on t

117 s that is compatible with the hemilabile OPh blocking group.

118 readed by a tetralactam macrocycle until the blocking groups are removed by enzyme cleavage.

119 A squaraine-derived substrate with large blocking groups at each end of its structure cannot be t

120 ycle threading kinetics, and (c) sialic acid blocking groups that prevent macrocycle threading until

121 is strategy relies on the design of a spacer-blocking hairpin (SBH) structure at the 5' end of the si

122 annels regulate excitability in neurons, and blocking HCN channel function has been proposed as a nov

123 Blocking hemichannel activity reduced the LTP of these e

124 Blocking HFD-induced cell proliferation by central deliv

125 troviral therapy was introduced, effectively blocking HIV replication and markedly reducing AIDS morb

126 T-WQ-IDL were also more effective than WQ in blocking HIV-1 Env-mediated membrane fusion and had high

127 Blocking IDO1 activity completely restored Th cell proli

128 Immunotherapy results in the production of blocking IgG/IgG4 antibodies that can inhibit IgE-depend

129 es increased in the Tg(CJD) hippocampus, and blocking IL-1 receptor signaling restored normal synapti

130 Blocking IL-33 activity with a soluble ST2 receptor sign

131 Blocking IL-6 or downstream signaling restored Bcl-2/Bcl

132 IL23R) protect against IBD, and, in animals, blocking IL23 reduces the severity of colitis.

133 Resolving chronic inflammation or blocking inflammatory signal transduction may prevent ca

134 Blocking inhibitory ionic currents abolishes small objec

135 This could be restored by blocking inhibitory pathways and, in particular, by supp

136 Studies have shown that blocking inhibitory receptors augments CD8 T cell functi

137 ticles, mediating uptake by immune cells, or blocking interaction with host cell receptors, making th

138 However, this blocking is not sufficiently specific and hence compromi

139 rs occludes the active site arginine finger, blocking its access to DnaA.

140 itor of metalloproteinases (TIMP)-3, through blocking its interaction with the endocytic scavenger re

141 NS5A sequesters NAP1L1 in the cytoplasm, blocking its nuclear translocation.

142 that promotes the degradation of BIN2 while blocking its substrate access.

143 inhibitor tenofovir (TDF), show efficacy in blocking K103 RT.

144 ate reactions may thus alter metal uptake by blocking key reactive sites.

145 Importantly, blocking Kir channels also inhibits flow-induced vasodil

146 ansparent p-AlGaN contact layer, an electron blocking layer and using this high quality AlN template:

147 that ADTs may be therapeutically enhanced by blocking lipid biosynthetic pathways.

148 nistration was still remarkably effective in blocking liver injury in this model.

149 In addition, Mdm2 deletion differed from blocking Mdm2 interaction with p53 family members, as Nu

150 This blocking mechanism does not conform to the commonly held

151 benzamide (AS-48) have similar efficacies in blocking membrane fusion and syncytium formation mediate

152 Finally, blocking mGlu3 activation in vivo prevented the stress-i

153 nce of mGluR2/3 blockade was not affected by blocking mGluR5.

154 ibody production, replenishing ADAMTS13, and blocking microvascular thrombosis despite persistent ADA

155 r-dependent Ad (HDAd) that expresses a PD-L1 blocking mini-antibody (mini-body; HDPDL1) as a strategy

156 Blocking mitochondrial Ca(2+) uniporter activity comprom

157 g eIF4E expression or mTOR activity and also blocking MNK1 phosphorylation of eIF4E.

158 otein kinase (AMPK) plays a critical role in blocking modifications to the chromatin landscape.

159 Blocking motor cortical output with lesions or pharmacol

160 ab, causing Bevacizumab to be ineffective in blocking MV-dependent VEGF receptor activation.

161 Conversely, blocking MyoD translation maintains the quiescent phenot

162 Blocking N-methyl-D-aspartate receptors or activation of

163 16 cells only when alpha1D was silenced, and blocking NCX1/3 increased cytosolic Ca(2+) concentration

164 tumour-associated macrophages or antibodies blocking negative regulators on T cells-could provide im

165 Blocking neither IL-6Ralpha/IL-6 nor IL-10 affected ESAT

166 gainst high-dose SIVsmE660 challenge and for blocking neutralization-resistant viruses within the SIV

167 dy defines a new p53-dependent mechanism for blocking NF-kappaB survival pathways in cancer cells.

168 the absence of N-terminally truncated forms, blocking Nix-mediated mitophagy stabilizes full-length M

169 Finally, blocking NMDA, but not GABA, receptors causes ATM levels

170 Blocking Nrp-2 significantly reduced invasion of Colo320

171 Blocking NRSF transiently after eFSE prevented granule c

172 We found that blocking NS cleavage increased association of the full-l

173 In contrast, in vivo blocking of beta1 integrins or alpha4 integrins did not

174 In vivo blocking of beta2 integrins (CD18) significantly reduced

175 Together, the current study suggests that blocking of CB1 ameliorates Diet-Induced Obesity and met

176 ble for SIV infection of SM in vivo and that blocking of CCR5 does not prevent ex vivo infection of p

177 We demonstrate that in vivo blocking of CXCL1 and CXCL2 can significantly reduce the

178 Finally, blocking of CXCR6 with its ligand CXCL16 significantly i

179 es in functionality of CD4 T cells following blocking of different inhibitory receptors, and we confi

180 Blocking of FDC secretion of IFN-alpha restored B cell t

181 cribe a second function of PtDd, namely, the blocking of HD5.

182 king of individual animals revealed that the blocking of neutrophil recruitment leads to rapid mortal

183 The data also show that blocking of the Galpha13 protein from binding to the cyt

184 In animal models of acute ischaemic stroke, blocking of the leukocyte-endothelium adhesion by antago

185 and Bovine serum albumin (BSA) was used for blocking of the non-specific binding sites.

186 Furthermore, specific blocking of the proximal 3'UTR reduced surface expressio

187 ex vivo intestinal tissue sections, despite blocking of the receptor with transferrin (Tf) noncompet

188 ficking to the lungs was assessed by in vivo blocking of these integrins before airway exposure to Al

189 Removal or blocking of Thy-1, or blocking Thy-1-beta integrin inter

190 ellular signal-regulated kinases 1 and 2, or blocking or deleting the mitogen- and stress-activated k

191 ze through these narrow vessels, transiently blocking or occluding the vessels they pass through.

192 Blocking or reducing GJ communication during HIV infecti

193 r mechanism of action is dominated by signal blocking or the cytotoxicity of Fc-driven innate immune

194 GAPDH bound Ape1 in the SMC nucleus, and blocking (or oxidation) of GAPDH active site cysteines s

195 Furthermore, blocking oxytocin signaling in the CeL prevented the sup

196 CA3 region of P301S mice were attenuated by blocking p25 generation.

197 ation and thus reduces surveillance, whereas blocking P2Y12 receptors does not affect membrane potent

198 Blocking p75 cleavage using inhibitor X (Inh X), a compo

199 PAR4 represents an attractive alternative to blocking PAR1 for antiplatelet therapy in humans.

200 egion include randomly occurring atmospheric blocking patterns, ocean impacts on atmospheric circulat

201 Furthermore, blocking PD-1 with an antibody increased KLRG1(+) ILC-2

202 a potential therapeutic role of selectively blocking PD-L1 in the recipient.

203 ate December, it was followed by a prolonged blocking period in early 2016 that sustained the extreme

204 These observations indicate that blocking peripheral sensory input may prevent BTP and ta

205 Blocking phagocytosis or specific phagocytic receptors m

206 e behavior of breast cancer, indicating that blocking PI3K-AKT pathway-dependent beta-catenin accumul

207 acids in the PKR eIF2alpha binding site and blocking PKR kinase activity.IMPORTANCE The antiviral ki

208 s to evaluate the safety/tolerability and CP-blocking potential of 4 weekly doses (60 mg/kg) of the a

209 Blocking PRMT5 with novel, highly selective small molecu

210 sses cleavage of its cognate substrate while blocking probable formation of catalytically competent i

211 Blocking programmed cell death protein (PD)-1 signaling,

212 gy induce a high degree of sterile infection-blocking protection against sporozoite challenge in a st

213 Blocking RAGE signaling in cell and animal models has re

214 opment of more-effective entry inhibitors by blocking receptor interactions.IMPORTANCE Countries in w

215 Cue-reactivity can be reduced by blocking reconsolidation or facilitating extinction, whi

216 Locally, for the blocking-residue Tyr31 and the water molecules inside th

217 Sting, phosphorylated Tbk1 and, importantly, blocking reverse transcriptase activity suppressed the e

218 ivity, which can be functionally rescued via blocking RNF8-MIWI interaction in spermatids with an RNF

219 On the other hand, blocking Ser321 phosphorylation promotes RIPK1 activatio

220 idifies elements along this pathway, thereby blocking signal transmission.

221 ll formation, all of which were abolished by blocking SRA.

222 p of the Au nanoparticle displayed a thermal blocking state at temperatures below TB = 59 K and a rel

223 However, PD-1 blocking strategy can increase the risk of graft-versus-

224 he two, PNA blockers were the only efficient blocking strategy, allowing a reduction of mosquito 18s

225 ice with an electron-transmitting but phonon-blocking structure has emerged as a promising flexible t

226 In addition, blocking studies were performed in 2 atherosclerotic rab

227 Blocking studies with preinjection of a CXCR4 inhibitor

228 Our blocking studies, western blot, and tissue histological

229 ceptors in vivo, as evidenced by entrectinib blocking studies.

230 y inhibiting BIN2 through dual mechanisms of blocking substrate access and promoting degradation.

231 (1837 K) in zero field and a record magnetic blocking temperature of 60 K, including hysteresis with

232 errihydrite (inferred from Mossbauer-derived blocking temperatures), these samples showed reduced Fe

233 , as an alternative therapeutic modality for blocking TGF-beta signaling in humans.

234 This model suggests that blocking thalamocortical phasic firing would treat absen

235 Importantly, targeted therapies blocking the aberrant activity of these targets restore

236 Blocking the ability of 3C(pro) proteins from diverse en

237 anscription during terminal differentiation, blocking the action of a promiscuous activator on crypti

238 Here, we have shown that blocking the activation of PERK using GSK2656157 prevent

239 the blood into the brain and spinal cord by blocking the adhesion molecule alpha4-integrin.

240 of the classical pathway could be reduced by blocking the AP.

241 own in several AD transgenic mice lines that blocking the apoE/Abeta interaction with Abeta12-28 P re

242 ero-threshold' gain achievable by completely blocking the band-edge state with two electrons.

243 Blocking the CD70/CD27 interaction by mAb induced asymme

244 cipitate cancer by perturbing S phase and by blocking the Chk1-dependent response to replication fork

245 e activity of UBE4B or phosphorylated CBL by blocking the E2 approximately Ub binding site.

246 nderlying losartan's benefits by selectively blocking the effects of angiotensin IV (AngIV) at its re

247 icant selectivity among MMPs was achieved by blocking the enzymes' specificity pockets, nearby exosit

248 g a robust cell-mediated immune response and blocking the establishment of a latent viral reservoir i

249 Blocking the function of inhibitory receptors such as PD

250 ment activation both in vitro and in vivo by blocking the generation of C5a and the soluble form of T

251 Blocking the IFN-I receptor at the time of Nb treatment

252 Blocking the interaction between GDF15 and GFRAL with a

253 hionylation and acts as a dominant negative, blocking the interaction of MAL with its downstream targ

254 taking tumor DNA, increase of DNA sensing by blocking the interaction of SIRPalpha with CD47 preferen

255 tic that inhibits canonical Wnt signaling by blocking the interaction of the protein CBP with beta-Ca

256 reward signal even after lesions in m-ALT or blocking the mushroom bodies.

257 Blocking the p38 kinase pathway, either with direct inhi

258 on sensitive glycine residues play a role in blocking the pathway upon rigidification of the loop, si

259 tion, suppressing channel gating rather than blocking the pore of heterologously expressed human BK c

260 , this paper provides a potential target for blocking the progression of CVD.

261 was gene dosage-dependent and suppressed by blocking the proteasome, Hsp70-type molecular chaperones

262 ited RECON enzyme activity by simultaneously blocking the substrate and cosubstrate sites, as reveale

263 C6 maintains Ku70 in a hypoacetylated state, blocking the translocation of Bax to mitochondria and pr

264 uptake in human and mouse skeletal muscle by blocking the translocation of GLUT4 to the cell surface.

265 e quantitative contribution of each organ in blocking the transport of nanoparticles to solid tumors.

266 and impairing mammosphere formation, thereby blocking the tumor-forming ability and invasive capacity

267 Blocking the tyrosine phosphorylation of C-Raf with Src

268 Blocking the uptake of Ca(2+) by mitochondria causes red

269 endoscopic remission), with the final aim of blocking their progression and preventing bowel damage a

270 discharges in some trials, while completely blocking them in others.

271 direct GIRK channel activator ML297, whereas blocking these channels with barium increased firing and

272 Blocking these checkpoints on T cells has provided drama

273 ype I IFN and the nucleic acid sensing TLRs, blocking these pathways rescues the autoimmunity.

274 K inhibition enhances functional recovery by blocking this detrimental effect.

275 Blocking this pathway in HIV-1-producing cells resulted

276 rons activate this bottom-up connection, and blocking this signal eliminates normal premotor activity

277 Blocking this signal with morpholino technology or silen

278 ed that selinexor causes thrombocytopenia by blocking thrombopoietin (TPO) signaling and therefore di

279 Removal or blocking of Thy-1, or blocking Thy-1-beta integrin interactions, decreased mEV

280 In total, 268 sera were investigated for 50% blocking titer (BT50) values of virus-like particles (VL

281 Significantly higher serum blocking titers (geometric mean titer [GMT], 1,704) were

282 Moreover, paired sera showed that blocking titers of >/=160 were maintained over a 6-year

283 Therapeutic approaches aimed at blocking TLR7/8 activation would be predicted to increas

284 F-alpha-induced killing while simultaneously blocking TNF-alpha growth-promoting activities.

285 Conversely, blocking TNFalpha receptor signaling abrogated induction

286 face are crucial for the role of sigma(N) in blocking transcription activity and in maintaining the a

287 tion of maternal immune responses capable of blocking transmission of autologous HIV to the infant.

288 effects, and the efficacy of the effector in blocking transmission.

289 influencing DDR and support the rationale of blocking TRIP12 to improve radiotherapy outcomes.

290 These results suggest blocking TRPM2 activation in ECs is a potentially import

291 ality anti-Pfs25 antibodies for transmission blocking upon mosquito feeding.

292 isplaying the promising malaria transmission-blocking vaccine (TBV) target Pfs25.

293 Transmission blocking vaccines (TBV) which aim to control malaria by

294 Detailed experimental evidence of kink blocking validates classical theory and demonstrates tha

295 ion therapy should be much more effective in blocking VEGF signaling to EKR1/2.

296 ded DNA, inhibit vaccinia virus infection by blocking viral DNA replication and abrogating postreplic

297 n and that the antibody neutralizes HAstV by blocking virus attachment to cells.

298 The longest dwell closed time of the blocking was observed with rhodamine 19 butyl ester (C4R

299 The effects of CLEC12A blocking were further validated using CLEC12A knockout (

300 Obstacles blocking wider adoption of FIB-SEM include slow imaging