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1 oduced locally or reaching the pituitary via blood circulation.
2  chemotherapy agents while bypassing general blood circulation.
3 antial amounts of glucose into the mammalian blood circulation.
4 immediate changes in biomarker levels in the blood circulation.
5 ry to prepare for the increase in demand for blood circulation.
6 urther migrate to the lymph nodes and to the blood circulation.
7 lations that include dendritic cells) in the blood circulation.
8 nfolated SCKs, respectively) and a prolonged blood circulation.
9 endothelial cells, and improved graft tissue blood circulation.
10  of this network of vessels does not require blood circulation.
11 mployed in a rabbit model for extracorporeal blood circulation.
12 ion have dysmorphic hearts and an absence of blood circulation.
13 was lost within 30 min of reestablishing the blood circulation.
14 tinct from its role in establishing coronary blood circulation.
15 ody pigmentation and the inability to affect blood circulation.
16 ia and lack of enucleated red blood cells in blood circulation.
17 meostasis by returning interstitial fluid to blood circulation.
18 ary or metastatic tumors into the peripheral blood circulation.
19  eliminates about three quarters of LPS from blood circulation.
20 nt is to supply oxygen and nutrients through blood circulation.
21  by malignant prostate cells and released in blood circulation.
22 os prior to the commencement of a functional blood circulation.
23 a(2+)) concentration and finally reached the blood circulation.
24 ells elicited by small-sized tastants in the blood circulation.
25 ity of mutant embryos by E9-10 due to failed blood circulation.
26 livery in a microtissue array with simulated blood circulation.
27 y impairs the development of vasculature and blood circulation.
28  the extracellular tissue milieu back to the blood circulation.
29 of neutrophils from the bone marrow into the blood circulation.
30  and inflow tracts and a complete absence of blood circulation.
31 rdial edema, an elongated heart, and reduced blood circulation.
32 as cleaved by aggrecanases and secreted into blood circulation.
33 eostatic egress from the BM reservoir to the blood circulation.
34  the atrium and inflow tract and compromised blood circulation.
35 esident immune cells are exposed to the open blood circulation.
36 ucture required for efficient clearance from blood circulation.
37 also profoundly affected AAV9 persistence in blood circulation.
38 ma cells to undergo EMT and disseminate into blood circulation.
39 VEGFR2-targeted MBs rapidly cleared from the blood circulation (50% blood clearance after approximate
40 er injection, sufficient time is allowed for blood circulation, accumulation at the tumour site and s
41 EMP seeding the FL upon the establishment of blood circulation acquired c-Myb expression and gave ris
42 mpared to the naked enzyme suggesting longer blood circulation after intravenous (iv) administrations
43  4T1 breast cancer model, owing to prolonged blood circulation and 10-fold higher tumor PTX uptake by
44 t encapsulated drugs from degradation in the blood circulation and allow for slow and prolonged relea
45  AuNR-loaded PLTs (PLT-AuNRs) inherited long blood circulation and cancer targeting characteristics f
46 rate infected erythrocyte sequestration from blood circulation and contribute to adhesion-based compl
47 evealed prolonged Pt persistence in systemic blood circulation and decreased accumulation of Pt in th
48 Radioiodinated BTT-1023 cleared rapidly from blood circulation and distributed to liver and thyroid.
49 ow physicochemical characteristics influence blood circulation and early distribution.
50 the neutral surface charge required for long blood circulation and effectively downregulate MDR gene
51  are small ( approximately 50 nm), show long blood circulation and high tumor accumulation, and facil
52 d mosquito, Plasmodium sporozoites enter the blood circulation and infect the liver.
53         The passage of leukocytes out of the blood circulation and into tissues is necessary for the
54 ion studies showed an increased half-life in blood circulation and more effective tumor accuulation f
55 y rapid clearance of mutant virions from the blood circulation and nonspecific sequestration by the s
56 h types of nanotubes inside cells and in the blood circulation and organs of mice without any signifi
57 ), while a minimal amount was present in the blood circulation and quickly eliminated.
58             Cardiac function is required for blood circulation and systemic oxygen delivery.
59                    The interface between the blood circulation and the neural tissue features unique
60 ) allows them to persist for several days in blood circulation and to ensure transmission to mosquito
61                  Functionalization dependent blood circulation and tumor uptake were investigated thr
62 -responsive nanoparticles is inactive during blood circulation and under normal physiological conditi
63 se of its uniform cell properties, exclusive blood circulation, and ability to sustain rattling for p
64 ae destroy the colonic epithelium, enter the blood circulation, and disseminate to other organs such
65  neurotrophic agents, improved chorioretinal blood circulation, and inhibition of proinflammatory cyt
66 r identities prior to the onset of embryonic blood circulation, and their specification is crucial fo
67 causes global and pericardial edema, loss of blood circulation, and vascular defects characterized by
68 ethylene glycol (PEG) outer shell to prolong blood circulation; and (iii) surface-encoded internalizi
69  polyethylene glycol (PEG) chains to prolong blood circulation; and iii) sharp pH-responsive hydropho
70 n in self-assembly systems is limited during blood circulation because of a requisite concentration f
71                                         Once blood circulation becomes fully functional, the embryoni
72 d extraembryonic vasculatures are fusing and blood circulation begins.
73                                     A shared blood circulation between 2 mice (aka parabiosis) or rep
74   There was no significant difference in the blood circulation between polymeric carrier and payload;
75 giogenesis-are also thought to mobilize into blood circulation bone marrow-derived cells (BMDCs), whi
76 ciparum-infected erythrocytes sequester from blood circulation by binding host endothelium.
77                    We established a chimeric blood circulation by parabiosis between fetal chicks and
78 d from niches in the bone marrow (BM) to the blood circulation by the cytokine granulocyte colony-sti
79 ts, malaria sporozoites are removed from the blood circulation by the liver within minutes after inje
80                    Neutralization of CTCs in blood circulation can potentially attenuate metastases t
81 ministration and membrane destabilization in blood circulation could result in only a very small frac
82 range of physiological activities, including blood circulation, digestion and reproduction.
83 ect may lead to severe disruptions of normal blood circulation due to capillary occlusions.
84 heart (sih) embryos, lacking a heartbeat and blood circulation, exhibited severely reduced HSCs.
85            Cells and biomolecules exposed to blood circulation experience hydrodynamic forces that af
86 und receptor, tissue factor (TF), exposed to blood circulation following tissue injury and/or vascula
87  produced by the AAV vector were detected in blood circulation for >250 days after the one-time vecto
88 utants unable to bind to CAR remained in the blood circulation for a prolonged period.
89 these nanoplatforms are not activated during blood circulation for efficient tumor tissue accumulatio
90 nt breast cancer cells that have entered the blood circulation from primary mammary fat pad tumors or
91 r lectin of hepatocytes, rapidly clears from blood circulation glycoproteins bearing glycan ligands t
92 r phagocyte system (MPS) in vivo with a long blood circulation half-life of 10.1 +/- 3.3h, and potent
93 e mononuclear phagocyte system and excellent blood circulation half-lives of 16.4 +/- 2.9 and 12.0 +/
94 ll-functionalized SWNT formulation with long blood circulation (half-life of approximately 30 h) in v
95 These endothelial cells, without exposure to blood circulation, have an abnormal distribution within
96 ity in pneumococcal sepsis to eliminate from blood circulation host factors that contribute to coagul
97 s, which regulate the return of lymph to the blood circulation; however, these valves lacked the fibr
98 was arrested from E7.5, the time of onset of blood circulation; (ii) heterozygous G6PD(+/-) females s
99 eristics, because it is actively shed in the blood circulation in humans via specific cleavage of the
100 udy, we demonstrate a new method to evaluate blood circulation in the eye by combining in vivo PAM im
101 aser Doppler perfusion imaging revealed that blood circulation in the ischemic limb was significantly
102  reticuloendothelial system, causing a short blood circulation in vivo.
103 cretion of small molecules from the systemic blood circulation into urine is one of the physiological
104                                              Blood circulation is dependent on heart valves to direct
105 e respiratory pump, pulmonary parenchyma and blood circulation is essential for a normal lung functio
106   One of the most important functions of the blood circulation is O2 delivery to the tissue.
107 lls and increased tumor cell survival in the blood circulation, it was insufficient to affect the abi
108 drug leakage during preparation, storage, or blood circulation, lack of active targeting to tumor tis
109 ubility, reduce off-target toxicity, enhance blood circulation lifetime, and increase the amount of d
110 f VSV improved the persistence of VSV in the blood circulation, maintaining a more than 1-log-unit in
111         T cells obtained from the peripheral blood circulation may not reflect the biologically relev
112 fore organ retrieval and before cessation of blood circulation, metabolic pathways related to hypoxia
113 ne marrow-derived progenitors that enter the blood circulation, migrate through the pulmonary endothe
114 l show muscle degeneration, strongly reduced blood circulation, mispatterning of vessels, impaired sp
115  surgical procedures to be done, a patient's blood circulation needs to be stopped.
116 ce of miRNAs encapsulated within exosomes in blood circulation of DM1 patients.
117  of these four muscle-specific miRNAs in the blood circulation of DM1 patients.
118 ion) has become a standard method to prolong blood circulation of imaging probes and other proteins,
119 evere combined immunodeficiency mice extends blood circulation of intravenous Ad5 but decreases its e
120 ed carbon nanotubes (SWNTs), we measured the blood circulation of intravenously injected SWNTs and de
121 g dams, are efficiently transferred into the blood circulation of lactationally-exposed neonatal pups
122 nding activity also cleared rapidly from the blood circulation of mice, with radioactivity accumulati
123 PG-PEG block polymer) significantly enhanced blood circulation of the drug and accumulation in tumor
124                            The half-lives in blood circulation of two phosphorylated GALNS enzymes we
125  soluble endoglin (sEng), is elevated in the blood circulation of women with preeclampsia and contrib
126  opportunity to study the effects of lack of blood circulation on the morphogenesis of endothelial ce
127                           In vivo studies of blood circulation pathologies have great medical relevan
128                 Temporary occlusion of liver blood circulation prevented CBLB502 from protecting hema
129         Venous valves play a crucial role in blood circulation, promoting the one-way movement of blo
130                        Sporozoites enter the blood circulation, reach the liver, and infect hepatocyt
131 -8.5, prior to cardiac function and systemic blood circulation, revealed that capillary plexi formed
132 that eliminating plasma fibronectin from the blood circulation reverses the prometastatic effects of
133 ne content and presence of heme in LDL after blood circulation suggest that LDL is modified, in part,
134      Bioluminescence was dependent on intact blood circulation, suggesting that the colonic environme
135 polymer-coated SWNTs exhibit remarkably long blood circulation (t(1/2) = 22.1 h) upon intravenous inj
136 bcutaneous A549 lung tumors showed prolonged blood circulation (t(1/2), approximately 28 h) and incre
137 ate, using Ncx1(-/-) mice that lack systemic blood circulation, that the E9 yolk sac (YS) and the int
138  that at the interface between the brain and blood circulation, the epithelial layers of the choroid
139 abiotic mice with separate organs but shared blood circulation, the majority of dermal DCs failed to
140 f protochordate colonial tunicates sharing a blood circulation, there exists an exchange of somatic s
141 otic mice with separate organs, but a shared blood circulation, there was no mixing of LCs.
142 young healthy mouse, thus providing a shared blood circulation through parabiosis, or through repeate
143 pleen) and are rapidly cleared from systemic blood circulation through the renal excretion route.
144                The tracer remained stable in blood circulation throughout the study and accumulated t
145 In vivo, these nanoparticles showed a longer blood circulation time (t(1/2) approximately 24.2 min) t
146 radable nanoparticles (NPs) to sustain their blood circulation time and made them small enough to ext
147 lding the Ad surface, accomplishing extended blood circulation time and reduced immunogenicity as wel
148 onjugation of PEG on proteins prolongs their blood circulation time and reduces immunogenicity by inc
149                          It exhibited longer blood circulation time compared with free Dox, and there
150                                The ultralong blood circulation time suggests greatly delayed clearanc
151 he design of the dendrimer carrier optimized blood circulation time through size and molecular archit
152              BCMs possessed a longer in vivo blood circulation time when compared to NCM.
153 ake, and oral bioavailability, with extended blood circulation time, increased tumor accumulation, en
154 lexes exhibited greater stability, increased blood circulation time, reduced renal clearance, increas
155 ctions; second, the nanoemulsions had a long blood circulation time; finally, the concentrated glutat
156 on 6 (G6, 6.7nm) dendrimers showed extended blood circulation times and increased accumulation in th
157  to form the envelopes and obtained extended blood circulation times following i.v. administration an
158 greater than the renal threshold have longer blood circulation times in mice than do linear polymers
159 ze of the overall assembly promotes extended blood circulation times in vivo.
160 -weight platinum anticancer drugs have short blood circulation times that are reflected in their redu
161 noprobes can be engineered to achieve longer blood circulation times, specific clearance pathways, an
162 ofunctionalization efficiencies, and enhance blood circulation times.
163               By contrast, in the absence of blood circulation, tissue P(O2)in vitro decreases more m
164 rst objective in treating CLI is to increase blood circulation to the affected limb.
165 ty to deliver antigens rapidly from the open blood circulation to the secluded follicles.
166 ation is limited due to rapid clearance from blood circulation, transfection of nontarget tissues, to
167 eveloped, enabling thus far the longest SWNT blood circulation up to 1 day, relatively low uptake in
168 of LDL- formation was studied during ex vivo blood circulation using a model system resembling clinic
169       This necessitates the establishment of blood circulation, which is initiated during the early s
170 le to minimize the premature drug release in blood circulation while releasing drug on-demand at tumo
171 ly in combination with a simplified model of blood circulation with three ammonia-detoxifying compart

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