ライフサイエンスコーパス: blood culture

1 ance of bacteremia >/=4 days after the index blood culture.

2 enefit if therapy was initiated prior to the blood culture.

3 clyA qPCR diagnostic was 40% as sensitive as blood culture.

4 between 45 and 365 days after the first MSSA blood culture.

5 nventional quantitative PCR (qPCR) assay and blood culture.

6 iate antifungal therapy following a positive blood culture.

7 Thirty-one (52%) grew M. tuberculosis on blood culture.

8 cally relevant Candida species directly from blood culture.

9 000 and 2014, 38,206 (94%) of whom had their blood cultured.

10 o underwent laboratory evaluations including blood cultures.

11 a microbiologic database of positive fungal blood cultures.

12 mic HAP, telavancin resulted in clearance of blood cultures.

13 test (RDT) can rapidly diagnose typhoid from blood cultures.

14 or the rapid, on-demand analysis of positive blood cultures.

15 y being applied to patients without positive blood cultures.

16 ered from monomicrobial and 33 polymicrobial blood cultures.

17 ability to identify pathogens from positive blood cultures.

18 but may be suboptimal in mixed Gram-negative blood cultures.

19 les in the form of Escherichia coli infected blood cultures.

20 , blaIMP, and blaOXA) directly from positive blood cultures.

21 ing in 904 nonduplicative subjects with 1808 blood cultures.

22 on and parasite antigen stimulation in whole-blood cultures.

23 n of a broad range of bacteria from positive blood cultures.

24 Gram-negative bacilli commonly isolated from blood cultures.

25 for most of the organisms found routinely in blood cultures.

26 6, we isolated 29 183 pathogens from 194 539 blood cultures.

27 om bronchoscopy specimens (32 strains) and a blood culture (1 strain) and were identified by sequenci

28 A total of 252 blood cultures, 126 in each group, were included in the

29 e at patient level were selected: (1) take 2 blood cultures, (2) take cultures from suspected sites o

30 the following variables: Number of positive blood cultures (3/3 blood cultures or the majority if mo

31 iteria were investigated: 1) any culture, 2) blood culture, 3) any culture plus IV antibiotics, 4) bl

32 Early-discharge patients had more positive blood cultures (37 [35%] vs 4 [14%]; P=.04) but required

33 Of 63,066 blood cultures, 7,296 (12%) were positive for at least o

34 y response syndrome criteria plus an ordered blood culture, all within 24 hours of hospital admission

35 (enrollment criteria were physician-ordered blood culture and complete blood count [CBC]), and 102 c

36 Diagnosis of tularemia by blood culture and nucleic acid-based diagnostic tests is

37 Gram-positive and Gram-negative organisms in blood culture and the FilmArray blood culture identifica

38 th sepsis or septic shock who had a positive blood culture and were homozygous for the SNP associated

39 yptic soy broth was inoculated from positive blood cultures and a saline suspension was inoculated to

40 guideline could decrease the rates of total blood cultures and cultures collected from central venou

41 ndocarditis (IE) is based on the yielding of blood cultures and echocardiographic findings.

42 ed these documents when considering ordering blood cultures and for guidance about the culture source

43 Most diagnoses (87.5%) were confirmed by blood culture, and asymptomatic bacteremia and stool she

44 ulture or PCR, pleural fluid culture or PCR, blood culture, and immunofluorescence for P. jirovecii d

45 ection (urine culture, complete blood count, blood culture, and wound culture) in the 7 days after di

46 Blood cultures are often obtained as part of the evaluat

47 Blood cultures are often obtained when clinicians suspec

48 Blood cultures are the mainstay of laboratory diagnosis,

49 f 0%, 0%, 30%, and 100% and CFU detection of blood culture at 0%, 0%, 0%, and 10% positive, respectiv

50 fficacy endpoints were percentage of sterile blood cultures at 72 hours and clinical success rate ass

51 d a systematic, standardised surveillance of blood culture-based febrile illness in 13 African sentin

52 s of antimicrobial binding resins present in blood culture (BC) bottles in removing meropenem, ceftol

53 The importance of blood culture (BC) volume for detection of bloodstream i

54 es and technologies are available to improve blood culture (BC)-based diagnostics.

55 the microarray-based Verigene Gram-negative blood culture (BC-GN) assay in the identification of 8 g

56 haracteristics of the Verigene Gram-positive blood culture (BC-GP) assay were evaluated in pediatric

57 dvanDx, Wolburn, MA), Verigene Gram-Positive Blood Culture (BC-GP; Nanosphere, Northbrook, IL), and m

58 Blood cultures (BCs) are the standard method for diagnos

59 Multivariate analysis revealed blood cultures before antibiotic therapy (hazard ratio,

60 Bundle elements are as follows: 1) blood cultures before antibiotics; 2) parenteral antibio

61 A recurrent infection was defined as a MSSA blood culture between 45 and 365 days after the first MS

62 infection (PJI) diagnosis using an automated blood culture bottle system for periprosthetic tissue cu

63 infection (PJI) diagnosis using an automated blood culture bottle system for periprosthetic tissue cu

64 on of the mecA gene directly from a positive blood culture bottle.

65 nel-based molecular diagnostics for positive blood culture bottles (BCBs) has not been rigorously ass

66 testing of antifungal susceptibilities from blood culture bottles by disk diffusion and Etest and th

67 with the adoption of tissue inoculation into blood culture bottles compared to conventional technique

68 hus, antifungal disk diffusion directly from blood culture bottles is a rapid and easy method for flu

69 ulture of periprosthetic tissue specimens in blood culture bottles is more sensitive than conventiona

70 clusion, culture of periprosthetic tissue in blood culture bottles is not only more accurate than but

71 pact of culture of periprosthetic tissues in blood culture bottles on laboratory workflow and cost.

72 e specimens are obtained and inoculated into blood culture bottles or four periprosthetic tissue spec

73 nualized labor cost savings of culture using blood culture bottles was $10,876.83 (+/-$337.16).

74 Culture in blood culture bottles was cost-effective, based on the e

75 A total of 419 yeast-positive blood culture bottles were studied, consisting of 258 cl

76 Inoculated blood culture bottles were weighed to estimate volume.

77 scence), was tested on Bactec and BacT/Alert blood culture bottles which signaled positive on automat

78 recovered from both solid medium and spiked blood culture bottles, and the results were obtained in

79 g inoculation of periprosthetic tissues into blood culture bottles, the greatest accuracy of diagnosi

80 nes (mecA, vanA/B, and blaKPC) from positive blood culture bottles.

81 cterial and fungal isolates in 784 simulated blood culture bottles.

82 n Candida species causing BSI, directly from blood culture bottles.

83 sing conventional techniques with culture in blood culture bottles.

84 lycolate broth) compared to inoculation into blood culture bottles.

85 ndle of care for patients with sepsis (i.e., blood cultures, broad-spectrum antibiotic agents, and la

86 kg of IV fluids, infectious workup including blood cultures, broad-spectrum antibiotics, and mechanic

87 for identification of S. aureus from Bactec blood culture broth.

88 cillin resistance in prospectively collected blood culture broths containing Gram-positive cocci.

89 erminants (mecA, vanA, and vanB) in positive blood culture broths.

90 genetic resistance determinants in positive blood culture broths.

91 aneous identification of pathogens in spiked blood cultures by means of a metabolomic "fingerprint" o

92 Microorganisms in positive blood cultures can also be identified within 1-2.5 hours

93 identification of microorganisms in positive blood cultures can be performed in minutes using commerc

94 Primary outcome was the total number of blood cultures collected per 100 patient-days.

95 6.0% reduction after the intervention in the blood culture collection rate (incidence rate ratio, 0.5

96 riate antibiotic therapy was determined from blood culture collection time to the administration of t

97 The time from blood culture collection to organism identification was

98 The median (interquartile range) time from blood culture collection to the administration of approp

99 A total of 1,847 blood cultures containing Gram-negative organisms were t

100 ital patients with bacteremia and those with blood culture contaminants and from nonhospital carriage

101 nd outcomes for patients with bacteremia and blood cultures contaminated with coagulase-negative Stap

102 (11.2 to 7.6/1000 patient-days; P=.006) and blood culture contamination (4.9 to 2.3/1000 patient-day

103 The monthly rate of blood culture contamination for all nurse-drawn and phle

104 on, KPC infection, all-cause bacteremia, and blood culture contamination in a high-risk LTACH populat

105 as associated with a significant decrease in blood culture contamination in patients undergoing blood

106 Blood culture contamination is a clinically significant

107 andomized crossover study directly comparing blood culture contamination rates using chlorhexidine ve

108 Blood culture contamination was significantly reduced th

109 ISDD) experienced a significant decrease in blood culture contamination while the nurses (did not us

110 positive for multidrug-resistant organisms, blood culture contamination, health care-associated bloo

111 ng hospital-acquired bloodstream infections, blood culture contamination, or clinical cultures yieldi

112 ve tests from urine Xpert, urine LAM and MTB-blood-culture correlated with PCs (p < 0.001 for both).

113 ium BSI for whom initial isolates, follow-up blood culture data, and daptomycin administration data w

114 (1) fever/sepsis screening checklist and (2) blood culture decision algorithm.

115 incidence of hospitalizations with positive blood cultures decreased by 17% (P = .006), and hospital

116 of septicemia hospitalizations with positive blood cultures decreased from 50% to 30% (P < .001).

117 A systematic approach to blood cultures decreased the total number of cultures an

118 d colonies and 30 min from positive (spiked) blood cultures, demonstrating the potential clinical uti

119 bottles which signaled positive on automated blood culture devices and were positive for yeast by Gra

120 to that of either empirical therapy (ET) or blood culture-directed therapy (BCDT).

121 phlebotomy procedures in patients requiring blood cultures due to clinical suspicion of serious infe

122 Of the 232 blood cultures evaluated (223 monomicrobial and 9 polymi

123 Blood cultures flagged as positive by automated blood cu

124 2.5 h, thus allowing rapid identification of blood cultures flagged positive.

125 ith erythema migrans with a positive skin or blood culture for Borrelia burgdorferi were enrolled in

126 the presence of an eschar and tested with a blood culture for Orientia tsutsugamushi, three differen

127 hospitals from 2003 to 2010 who had positive blood cultures for MSSA.

128 ing 61.7% (n = 37/60) of those with positive blood cultures for pneumococcus.

129 (MLW) has routinely collected specimens for blood culture from febrile patients, and cerebrospinal f

130 We obtained 1692 blood cultures from 847 children.

131 flammatory and regulatory cytokines in total blood cultures from patients with and without chronic pe

132 In a two-center trial, 155 blood cultures from the BD Bactec FX system and 212 from

133 ration of treatment and utility of follow-up blood cultures (FUBC) have not been studied in detail.

134 he identification of organisms from positive blood cultures generally takes several days.

135 or influenza viruses, and 6 (43%) of 14 with blood cultures grew pneumococcus, all serotype 5.

136 Blood culture growing pathogenic bacteria.

137 As blood culture has several limitations, there is a need f

138 ureus (MSSA) and MRSA directly from positive blood cultures has demonstrated benefits in both patient

139 entification of microorganisms from positive blood cultures has improved clinical management and anti

140 Unrestrained use of blood cultures has serious implications for patients inc

141 The performance of the FilmArray blood culture identification (BCID) panel has been studi

142 The FilmArray blood culture identification (BCID) panel is a rapid mol

143 e recently implemented the BioFire FilmArray blood culture identification panel (BCID) coupled with s

144 re pathogens on a rapid, multiplex PCR-based blood culture identification panel (BCID) that included

145 The FilmArray blood culture identification panel (BioFire Diagnostics

146 organisms in blood culture and the FilmArray blood culture identification panel were assessed for the

147 The unresolved blood culture identification sensitivity for all target

148 valuated hospitalized patients with positive blood cultures identified via MALDI-TOF MS combined with

149 qPCR was significantly faster than blood culture in terms of detection of typhoid and parat

150 h MDV B cells isolated from spleen, bursa or blood cultured in the presence of soluble CD40L.

151 culture contamination in patients undergoing blood cultures in an Emergency Department setting.

152 f patients withActinomycesspp. isolated from blood cultures in our NHS Trust and found that this is n

153 gal results from cerebrospinal fluid or from blood cultures in patients with clinical meningitis were

154 Clinicians should obtain blood cultures in patients with evidence of PVC infectio

155 five of these patients had multiple positive blood cultures, indicating true clinical infection.

156 y hospitals and large health centers perform blood culture instead.

157 om adults and incubated in the BacT/Alert 3D blood culture instrument.

158 od cultures flagged as positive by automated blood culture instruments and demonstrating only Gram-po

159 gents (HR, 0.91; 95% CI, .85-.96), had fewer blood cultures (IRR, 0.78; 95% CI, .71-.86), and had few

160 Convalescent-phase serology is impractical, blood culture is slow, and many pathogens are fastidious

161 Blood culture is the gold-standard diagnostic test, but

162 as it identified a model set of 17 clinical blood culture isolates and microbial reference strains w

163 We tested 187 blood culture isolates of 5 Candida spp. (120 C. albican

164 ht nursing units at RWJUH were provided with blood culture kits containing either chlorhexidine (CH)

165 Automated blood culture, malaria microscopy with Giemsa-stained bl

166 Automated blood culture, manual speciation, serotyping, and antimi

167 agnostic test approved for use with positive blood culture material.

168 New blood culture media containing antibiotic-binding polyme

169 rect detection of Staphylococcus aureus from blood culture medium.

170 A Gram-negative (GN) blood culture microarray assay with an antimicrobial ste

171 having an IBI (11.0% and 1.7% of those with blood culture (n = 1258), respectively).

172 n = 20/28), mycobacterial/fungal and aerobic blood culture (n = 15/25 and n = 9/37, respectively), bo

173 consecutive inpatients with positive fungal blood cultures (n = 215) or suspected fungemia (n = 12).

174 dentifying infection in suspected cases with blood culture-negative tests.

175 ither confirmed blood-culture positivity, or blood-culture negativity.

176 The proportion of positive blood cultures, number of isolates, geographical represe

177 INTERPRETATION: The proportion of positive blood cultures, number of isolates, geographical represe

178 Blood cultures obtained from hospital-admitted patients

179 hospitalized medical patients with positive blood cultures obtained on the day of admission.

180 gns and symptoms of sepsis, but four sets of blood cultures obtained prior to initiation of antibioti

181 erochromatin, we treated in vitro peripheral blood cultures of 5 patients with balanced constitutiona

182 d characterisation of bacteria from positive blood cultures of sepsis patients.

183 nfirmed TB; 41/132 (31.1%) had a positive TB blood culture, of these 9/41 (22.0%) died within 90-days

184 There were 783 patients with positive blood cultures; of those patients, 364 (115 control, 104

185 cimens were considered to be true positives, blood culture only exhibited 28.57% sensitivity.

186 By contrast, in patients with a negative blood culture, only two (3%) of 58 who received gatiflox

187 or "confirmed" bacterial pneumonia (positive blood culture or positive lung aspirate or pleural fluid

188 th those of pneumococcal (per respiratory or blood culture or urine antigen) and all-cause non-S. aur

189 bles: Number of positive blood cultures (3/3 blood cultures or the majority if more than 3), 5 points

190 if either sputum Gram stain, sputum culture, blood culture, or the immunochromatographic (ICT) BinaxN

191 was isolated from cardiac tissue specimens, blood cultures, or other biopsy specimens.

192 suspected sepsis was determined by the first blood culture order with concurrent antibiotic initiatio

193 ed from 1801 hospitalized patients who had a blood culture ordered for routine standard of care; 250

194 easurement were assessed in patients who had blood cultures ordered and patients with severe sepsis,

195 Among hospitalizations with blood culture orders, rates of lactate measurement incre

196 score for enterococcal IE-Number of positive blood cultures, Origin of the bacteremia, previous Valve

197 Typhi, participants were assessed with daily blood culture over a 2-week period and diagnosed with ty

198 We evaluated the Portrait Staph ID/R blood culture panel (BCP) multiplex PCR assay (Great Bas

199 Hospitalized adult patients with blood culture pathogens on a rapid, multiplex PCR-based

200 B. clarridgeiae, as documented by enrichment blood culture, PCR, and DNA sequencing.

201 41,668 of the 51,878 admitted children had a blood culture performed.

202 antibiotics for at least 4 of 7 days, and 6) blood culture plus IV antibiotics for at least 4 of 7 da

203 ture, 3) any culture plus IV antibiotics, 4) blood culture plus IV antibiotics, 5) any culture plus I

204 Patients were included if they had a blood culture positive for MSSA and received definitive

205 crotising enterocolitis (Bell stage 2 or 3), blood culture positive sepsis more than 72 h after birth

206 vention for adult hospitalized patients with blood cultures positive for CoNS.

207 rs to determine the number of single-patient blood cultures positive for MRSA and methicillin-suscept

208 d HO-SAB was collected (defined as 1 or more blood cultures positive for S. aureus taken from a patie

209 tment on day 8; microbiological failure (ie, blood cultures positive for Salmonella enterica serotype

210 Neurolisteriosis mortality was higher in blood-culture positive patients (OR 3.67 [1.60-8.40], p=

211 Urine Xpert, urine LAM and TB-blood-culture positive patients clustered similarly on t

212 nomannan (LAM) combined identified 88% of TB blood-culture-positive patients, including 9/9 who died

213 on, and subpopulations with either confirmed blood-culture positivity, or blood-culture negativity.

214 nts, we aimed to report the prevalence of TB-blood-culture positivity, performance of rapid diagnosti

215 fect of a new clinical practice guideline on blood culture practices in a 36-bed, combined medical/su

216 nts (123 cases; 246 controls) diagnosed with blood culture-proven sepsis were matched 1:2 by age, sex

217 Both the blood-culture-proven bacteremia case subjects and health

218 supplement Gram stain results from positive blood cultures provide specific organism information to

219 ly identify organisms directly from positive blood cultures: QuickFISH (AdvanDx, Wolburn, MA), Verige

220 The consecutive fresh blood cultures received in the laboratory were analyzed

221 Blood cultures remain the standard test for microbial di

222 anagement including echocardiography, repeat blood culture, removal of infectious foci, and antibioti

223 cardiac ischemia or injury, and new positive blood culture result.

224 sed in a slightly adapted form; 2/2 positive blood cultures resulted in 5 points, unknown origin of i

225 However, the time to positivity of blood culture results in this population is not known.

226 re systematically cultured and correlated to blood culture results indicated a substantial burden of

227 ime to positivity and proportion of positive blood culture results that become positive more than 24

228 nt difference in ICU readmission or positive blood culture results was observed.

229 atients (37.8%) with available mycobacterial blood culture results.

230 personnel, and dedicated pharmacist time for blood culture review and of making interventions to anti

231 -level in 59 culture-positive mono-bacterial blood culture samples with 90% accuracy.

232 Testing included 2,207 positive aerobic blood culture samples, 1,568 clinical and 639 seeded.

233 ude that CH and IT are equivalent agents for blood culture skin antisepsis.

234 For every additional 1 mL of blood culture specimen collected, microbial yield increa

235 While the criteria for achieving an adequate blood culture specimen in adults have been well describe

236 e pertaining to the collection of an optimal blood culture specimen, including timing, volume, and bo

237 We obtained blood culture specimens from participants presenting wit

238 s complicated by severe sepsis with positive blood culture Staphylococcus haemolyticus, septic shock,

239 nd 1 year and 2 years posttreatment in whole blood cultures stimulated with soluble egg antigen (SEA)

240 Whole-blood cultures stimulated with soluble Leishmania antige

241 positive blood cultures than a conventional blood culture system (12.1 h versus 14.9 h, P < 0.001) w

242 BacT/Alert Virtuo is an advanced, automated blood culture system incorporating improved automation a

243 clinical study demonstrated that the Virtuo blood culture system produced results comparable to thos

244 ompared the newly approved BacT/Alert Virtuo blood culture system to the BacT/Alert 3D system using 1

245 les were flagged as positive by an automated blood culture system.

246 rcoal-containing PF medium in the BacT/Alert blood culture system.

247 he BacT/Alert (bioMerieux, Inc., Durham, NC) blood culture system.

248 able to yeast were not detected by automated blood culture systems.

249 od do not overlap with those of conventional blood culture techniques and we are still learning how b

250 Changing epidemiology, advances in blood culture techniques, and new diagnostics guide the

251 version of the rapid Verigene Gram-negative blood culture test (BC-GN), a microarray that detects 9

252 Implementation of the Verigene Gram-positive blood culture test led to reductions in time to acceptab

253 cation and has the possibility to impact how blood culture testing is performed.

254 s were less likely to have a single positive blood culture than were nonneutropenic patients.

255 d significantly faster detection of positive blood cultures than a conventional blood culture system

256 tely reported negative BC-GN results in 8/13 blood cultures that grew organisms that were not represe

257 In this surveillance study, we analysed blood cultures that were routinely taken from adult and

258 ation and susceptibility testing of positive blood cultures, the performance of these methods, and th

259 retrospective, cross-sectional evaluation of blood culture time to positivity.

260 use of the Wampole Isolator 1.5-ml pediatric blood culture tube for the detection of fungemia in chil

261 and yields complete results in 2 h after the blood culture turns positive.

262 ata and microbiological tests were assessed: blood cultures, urine pneumococcal and legionella antige

263 eline period with the EOS calculator period, blood culture use decreased from 14.5% to 4.9% (adjusted

264 Secondary outcomes included blood culture use, antibiotic administration between 24

265 jective clinical markers, including positive blood cultures, vasopressors, and/or lactic acid levels.

266 ncture (IT) for skin antisepsis prior to all blood culture venipunctures, which were obtained by nurs

267 A total of 159 blood cultures (VersaTREK Trek Diagnostic Systems, Cleve

268 Sputum and blood cultures, viral polymerase chain reaction, urinary

269 Antibiotic exposure and blood culture volume affect detection of bacterial patho

270 before and up to 4 days after the first MSSA blood culture was collected.

271 tween 4 and 14 days after the first positive blood culture was collected.

272 Blood culture was performed in hospitalized children and

273 The prevalence of Salmonella in blood cultures was 0.8% (106/13,905).

274 n for all nurse-drawn and phlebotomist-drawn blood cultures was modeled using Poisson regression to c

275 To investigate the value of repeat blood cultures, we analyzed 500 episodes of bacteremia t

276 A total of 324 patients with a positive CoNS blood culture were included; 246 were deemed to have con

277 A total of 12 683 and 9524 blood cultures were analyzed from Lwak and Kibera, respe

278 In all, 102 blood cultures were analyzed using the BC-GP assay.

279 A total of 1807 blood cultures were drawn before the intervention during

280 Blood cultures were monitored at PLGH for Lactobacillus

281 Blood cultures were negative 72 hours after the first do

282 Blood cultures were negative for bacterial growth.

283 d patients with a clinical infection in whom blood cultures were obtained and empiric therapy with br

284 l-term infants younger than 60 days for whom blood cultures were obtained.

285 350 cells/microL were included; tuberculosis blood cultures were performed in all.

286 Blood cultures were repeated within 2-4 days of bacterem

287 Between 1998 and 2014, 167,028 blood cultures were taken from adult and pediatric medic

288 n active antibiotic for at least 2 days when blood cultures were taken, and subsequent episodes in th

289 ion in IL-1beta and IL-6 production in whole blood cultures, whereas TNFalpha production remained una

290 These tests may lack sensitivity (eg, blood culture, which is only positive in a small proport

291 ation in 12 out 12 cases of E. coli positive blood cultures with an average score of 2.19 +/- 0.09 co

292 BC-GN detected 5/5 and 1/1 clinical blood cultures with blaCTX-M and blaVIM.

293 = .006), and hospitalizations with positive blood cultures with concurrent vasopressors and/or lacti

294 for capturing hospitalizations with positive blood cultures with concurrent vasopressors and/or lacti

295 A total of 104 blood cultures with different Candida species (28% C. al

296 acT/Alert Pediatric FAN and Bactec Peds Plus blood cultures with Gram-negative organisms at two terti

297 ristics of S. aureus CAP (per respiratory or blood culture) with those of pneumococcal (per respirato

298 pestis was identified directly from positive blood cultures within 20 to 45 min without further proce

299 anent intracardiac device, sterile follow-up blood cultures within 4 days after the initial set, no h

300 tics were associated with a 45% reduction in blood culture yield and approximately 20% reduction in y