ライフサイエンスコーパス: blood level

1 ount, human immunodeficiency virus [HIV] RNA blood level).

2 dherence to prednisolone despite nonadherent blood level.

3 P=0.0009) and mycophenolate mofetil (P=0.01) blood levels.

4 s may be an adequate surro-gate for baseline blood levels.

5 n predictor of posttransplantation phosphate blood levels.

6 e blood-brain barrier at approximately 2% of blood levels.

7 nships with human immunodeficiency virus RNA blood levels.

8 rrelated with subtherapeutic and therapeutic blood levels.

9 eurin inhibitors is generally guided by drug blood levels.

10 areas, with maximum values equal to systemic blood levels.

11 ased on relative BTEXS and 2,5-dimethylfuran blood levels.

12 pressants, despite relatively low tacrolimus blood levels.

13 , and tacrolimus targeted to relatively high blood levels.

14 le in hippocampal functions than circulating blood levels.

15 rleukin-6, interleukin-8, and interleukin-10 blood levels.

16 study group had lower tacrolimus dosages and blood levels.

17 Medications did not consistently predict blood levels.

18 es in the analysis of NIST SRM 955c (Caprine Blood) Level 3 and the certified human hairs IAEA 085 an

19 Importantly, blood levels after intrapulmonary administration of eith

20 .2 microg/mL, approximate median therapeutic blood levels) alone had no effect on EC permeability.

21 to train the ANN was validated by comparing blood levels among cigarette smokers from the National H

22 The fit of blood level and response to a linear model was good.

23 resulted in a temporary increase in albumin blood level and symptom improvement in 1 patient, but wa

24 dependent suppression of nocturnal melatonin blood levels and a stimulation of tumor growth and linol

25 We assessed reproductive hormone blood levels and angiographic CAD using core laboratorie

26 n-parenteral fashion as demonstrated by both blood levels and biologic effects of its delivery.

27 Strongest correlations between cord blood levels and maternal levels were observed for mater

28 s and the measurements of both the C-peptide blood levels and the proinsulin mRNA levels in the islet

29 y of cyclosporine for 6 months (adjusted for blood levels), and a short course of corticosteroids (1

30 fasting blood glucose, calcineurin inhibitor blood level, and HbA1c were obtained.

31 th EBF1 and IL12B strongly regulate IL-12p40 blood levels, and IL-12p40 polymorphisms may contribute

32 .i.d. on days +1 to +3 with dose adjusted by blood levels, and methylprednisolone (15 mg/kg day 0 to

33 ) 1, and IGFBP3 genes with IGF-I and IGFBP-3 blood levels, and prostate cancer (PCa) risk, among Cauc

34 t use of other medications that affect their blood levels, and the individual's specific drug-metabol

35 flunomide therapy with specifically targeted blood levels appears to be a safe and effective treatmen

36 Oral sirolimus is tolerable, adequate blood levels are achievable, and there is a low rate of

37 Assays of drug blood levels are used for therapeutic immunosuppressive

38 Moreover, MIL blood levels at the end of treatment were similar in cur

39 daily dosing of tacrolimus to maintain whole blood levels between 10 and 20 ng/ml.

40 d SNPs significantly associated with IGFBP-3 blood levels, but none of these alter PCa risk; however,

41 iation (CvarC0 ) of dose-adjusted CsA trough blood levels (C0/dose) were recorded (CvarC0 =[SD (C0/do

42 ective and resulted in clinically achievable blood levels, clinical trials with TPA alone or in combi

43 given nicotine for up to 86 weeks to produce blood levels comparable with those of intermediate smoke

44 At blood levels comparable with tobacco smoking, nicotine i

45 h nutrient concentration is varied from high blood level concentrations (HBLCs) to low blood level co

46 gh blood level concentrations (HBLCs) to low blood level concentrations (LBLCs).

47 first week of therapy, and at weeks 4 and 6, blood levels continued to decline.

48 As such, because there is limited blood level data on individuals exposed to crude oil/fue

49 N-terminal pro-brain natriuretic peptide blood levels decreased by 620 pg/mL (P<0.001).

50 Despite therapeutic blood levels, doxycycline had no significant effect on M

51 stosterone levels may not accurately reflect blood levels during mini-puberty.

52 ere passed to the newborn rats with neonatal blood levels equal to that of the mothers for the 25-mg/

53 model of HFg, we showed that at an elevated blood level, Fg increases cerebrovascular permeability v

54 opathy, suggesting 35 ng/ml as the threshold blood level for tolerance induction.

55 with no known occupational exposure, median blood levels for all n-alkanes were below these quantifi

56 or the transplant recipients were STN or CsA blood levels for combined treatment greater than when ei

57 on was noted in the FFQ's ability to predict blood levels for subgroups defined by race, sex, and oth

58 ration and response and to determine optimal blood levels for treatment of acute mania.

59 Although high sCD14 blood levels have correlated with increased risk of dyin

60 Although the CsA blood level in human transplant patients is normally muc

61 n of corticosterone in an amount that led to blood levels in adrenalectomized subjects that match tho

62 sociated with lung function decline and uPAR blood levels in asthma subjects.

63 nd low density lipoprotein (LDL) cholesterol blood levels in men.

64 We strongly advise further study of HPC blood levels in the general population, children, and fe

65 Blood levels in the lowest effective range were 60% more

66 STN blood levels in transplant recipients during combination

67 a chain-dependent manner, modulated cytokine blood levels in tumor-bearing animals, and impaired tumo

68 demonstrated rapid renal clearance and lower blood levels in vivo compared with (99m)Tc-RP805.

69 Rats on high vitamin D achieved the highest blood levels (in the sufficient range) and significantly

70 ement of 5-methyltetrahydrofolic acid (5 MT) blood levels is one of several factors used to diagnose

71 Based on CQ blood level measurements, CQ resistance prevalence was e

72 od kidney volumes, creatinine and cystatin C blood levels, microalbuminuria, BP, and eGFR.

73 ssessed the geometric mean difference in IGF blood levels (N = 5684) across genotypes and the associa

74 Accordingly, decreasing serotonin blood levels normalizes bone formation and bone mass in

75 mo results in a greater than 120-fold higher blood level of 20-hydroxyeicosatetraenoic acid (20-HETE)

76 rovide mechanistic insight into the elevated blood level of ACE observed in patients on ACE inhibitor

77 Leflunomide was dosed to a targeted blood level of active metabolite, A77 1726, of 50 microg

78 The blood level of caffeine 1 h after intake was 3.1 +/- 1.6

79 isms, predictably and strongly influence the blood level of CRP.

80 WR also increases blood level of D-dimer, indicative of ongoing coagulatio

81 tly normal in women with depression, but the blood level of estradiol was significantly lower.

82 ascular diseases associated with an elevated blood level of Fg.

83 and as such are accompanied by an increased blood level of fibrinogen (Fg).

84 against the hypothesis that the circulating blood level of growth differentiation factor 11 (GDF11)

85 n was to identify factors that determine the blood level of hepatitis C virus (HCV) RNA.

86 The blood level of HIV DNA decreased in most patients.

87 , we found that hydrocortisone decreased the blood level of interleukin-10, a cytokine centrally invo

88 consistent with the fact that the peripheral blood level of neutrophils-which are very short-lived ce

89 and following treatment, the daily dose and blood level of tacrolimus remained stable and unchanged.

90 Based on an increased blood level of the beta human chorionic gonadotropin and

91 An elevated blood level of tumor necrosis factor (TNF)-alpha is a va

92 ncentration and response and that the target blood level of valproate for best response in acute mani

93 Blood levels of 16:1n-7 were associated with higher pros

94 lved in de novo lipogenesis, as reflected in blood levels of 16:1n-7, could be involved in the develo

95 We hypothesized that low blood levels of 25(OH)D in patients with chronic obstruc

96 nal low dose and a higher dose of sirolimus (blood levels of 3 ng/ml and 30-60 ng/ml, respectively) o

97 lso greater in the older group, and arterial blood levels of 6-(18)F-fluorodopamine were also higher.

98 o investigate variants associated with whole blood levels of a range of toxic metals.

99 Measuring blood levels of Abeta40 identified patients at high risk

100 Blood levels of activation markers, soluble CD163 (sCD16

101 Four patients who did not consistently have blood levels of active drug (A77 1726) above 40 microg/m

102 atients consistently sustaining the targeted blood levels of active drug, blood and urine viral load

103 gene have been identified as determinants of blood levels of adiponectin, an insulin-sensitizing adip

104 ter odor presentation, rats were sacrificed, blood levels of adrenocorticotropic hormone (ACTH) and c

105 with liver injury as manifested by increased blood levels of alanine transaminase in common for most

106 blood of albumin and apoA-I, which decreases blood levels of albumin and apoA-I/HDL.

107 ession might reduce proteinuria and increase blood levels of albumin and HDL.

108 in HT mice displayed significantly decreased blood levels of albumin, apoA-I, and HDL.

109 eristics, including serum Ig concentrations, blood levels of all leukocytes, and spleen number of tot

110 Blood levels of amino acids are important biomarkers of

111 ife, despite causing a sustained increase in blood levels of antioxidants.

112 have an adaptive response resulting in lower blood levels of AOPPs and AGEs.

113 Pretreatment blood levels of bacterial DNA (bDNA) were measured in 73

114 significantly decreased baseline peripheral blood levels of BDNF compared with healthy control (HC)

115 Several studies report reduced peripheral blood levels of BDNF in AD, but findings are inconsisten

116 er approximately doubled among subjects with blood levels of beta-carotene at the lowest quartile, as

117 eased conversion rates and increased fasting blood levels of beta-carotene.

118 reby reducing the hepatic bile acid pool and blood levels of bile acids.

119 However, running exercise increases blood levels of both beta-endorphin (an opioid) and anan

120 Urinary 8-hydroxydeoxyguanosine (8-OHdG), blood levels of C-reactive protein (CRP), malondialdehyd

121 Blood levels of calcineurin inhibitors were monitored, a

122 Blood levels of calcium, vitamin D, dihydroxyvitamin-D,

123 out concomitant formation of elevated, toxic blood levels of carboxyhemoglobin (COHb).

124 Pulse CO-oximeter' instruments can estimate blood levels of carboxyhemoglobin, methemoglobin, and to

125 However, prospective data on blood levels of carotenoids other than beta-carotene and

126 d fruit and vegetable intake and dietary and blood levels of carotenoids, vitamins C and E were exami

127 Blood levels of caspase 3 and TUNEL staining of liver we

128 stric administration of fatty acids elevated blood levels of CCK in wild-type mice but not Ildr1-defi

129 cally healthy participants identified higher blood levels of CCL2, CCL3, CCL11, CXCL7 and CXCL8 and l

130 CCL2, CCL3, CCL11, CXCL7 and CXCL8 and lower blood levels of CCL4.

131 t of these results, we found that peripheral blood levels of CD11b(+)Jag2(+) cells in mouse models of

132 ncreased risk of HIV-1 shedding in saliva as blood levels of CD4 cell counts decreased (p < 0.0001) a

133 immune system deterioration measured through blood levels of CD4+ T lymphocytes.

134 ean mass, food consumption, body length, and blood levels of cholesterol and nonfasted glucose, insul

135 gain, adiposity, and fatty liver; decreased blood levels of cholesterol, sugar, HbA1c, insulin, and

136 iological function, exemplified by measuring blood levels of creatinine and urea, and on various end

137 ine by gavage, resulting in strongly varying blood levels of cyclosporine, increased tumor developmen

138 Blood levels of cyclosporine, tacrolimus, creatinine, an

139 ecially when participants with nondetectable blood levels of DES were excluded (P = 0.002).

140 was strongest in the children of women whose blood levels of eicosapentaenoic acid and docosahexaenoi

141 In this study we examined the blood levels of EPCs and mature circulating endothelial

142 igonucleotide antagonist of MIR122 increased blood levels of EPO, reticulocytes, and hemoglobin.

143 DTA after injecting exogenous factor IX, the blood levels of factor IX that bind to endothelial cells

144 nts with severe trauma, we have measured the blood levels of five cytokines (tumor necrosis factor-al

145 Cord blood levels of free triiodothyronine (FT3), FT4, TSH, a

146 Changes in blood levels of FSH and LH also did not differ in the tw

147 Blood levels of gamma glutamyl transpeptidase (GGTP), a

148 The blood levels of gammadelta T cells were significantly in

149 Our conclusion is that elevating blood levels of GDF11 in the aged might cause more harm

150 We found that blood levels of ghrelin were reduced after VSG, but not

151 AG treatment increased the blood levels of GLP-1, but reversed the CP-induced incre

152 ndividuals, and is associated with increased blood levels of glucose in patients with type 2 diabetes

153 The transgenic mice tended to have lower blood levels of glucose than control mice, associated wi

154 s engineered to express insulin have reduced blood levels of glucose, are less likely to develop diab

155 The NQO1-/- mice showed lower blood levels of glucose, no change in insulin, and highe

156 treated db/db mice; 3) significantly reduced blood levels of glucose, triglyceride, and free fatty ac

157 Diabetes is associated with lower blood levels of H2S.

158 CKD were positive for hCMV protein and that blood levels of hCMV IgG inversely correlated with red b

159 Follow-up included blood levels of hemoglobin and ferritin at 8 and 12 mont

160 othesis that person-to-person variability in blood levels of hepatitis C virus (HCV) RNA can be expla

161 Elevated blood levels of homocysteine (Hcy), hyperhomocysteinemia

162 Elevated blood levels of homocysteine are a significant risk fact

163 Elevated blood levels of homocysteine are associated with an incr

164 Moderately elevated blood levels of homocysteine are weakly correlated with

165 Blood levels of homocysteine may be increased in Alzheim

166 lls many, if not all, of these criteria, and blood levels of hs-CRP are now commonly used in clinical

167 acebo, Mn(2+)-supplemented rats showed lower blood levels of ICAM-1 (17%, p < 0.04), cholesterol (25%

168 Blood levels of IgG autoantibodies that bind to SCCA pro

169 Chronically elevated blood levels of IL-10 in rats were achieved by administr

170 ases the incidence of diabetes and decreases blood levels of IL-12p40.

171 IS also produced increased blood levels of IL-1beta, but only in adrenalectomized s

172 Blood levels of IL-6 and MCP-1 remained unchanged, and h

173 hylene was detected prior to the increase of blood levels of inflammatory cytokines and stress-relate

174 s increase was accompanied by an increase in blood levels of inflammatory cytokines, vital sign chang

175 nous injections of arginine and glucose, and blood levels of insulin and C peptide were measured with

176 between serum C-reactive protein and fasting blood levels of insulin, glucose, and hemoglobin A1c (Hb

177 tudies suggest an association between higher blood levels of insulin-like growth factor I (IGF-I) and

178 Additionally, the blood levels of insulin-like growth factor-1, hepatocyte

179 Blood levels of interleukin-6 (IL-6), C-reactive protein

180 he following biochemical measurements: whole-blood levels of ionized calcium, plasma levels of intact

181 -dependent and was associated with increased blood levels of iron-nitrosyl-hemoglobin.

182 xcretion of lactate as well as a decrease in blood levels of lactate in c/ebpdelta-/- mice.

183 o be significantly associated with increased blood levels of LDL (OR, 1.07; 95% CI, 1.04-1.09; P < 0.

184 tudy was to evaluate the association between blood levels of lead and cadmium and peripheral arterial

185 Blood levels of leptin and adiposity indexes (body mass

186 h DNA methylation levels are associated with blood levels of liver enzymes and hepatic steatosis.

187 As compared with men whose blood levels of long-chain n-3 fatty acids were in the l

188 Base-line blood levels of long-chain n-3 fatty acids were inversel

189 e degeneration (prcd) have lower than normal blood levels of long-chain polyunsaturated fatty acids,

190 Although blood levels of major cytokines and Salmonella-specific

191 Associations between blood levels of manganese and lead and biomarkers were a

192 was an inverse relationship between baseline blood levels of marine omega-3 fatty acids and the rate

193 into joints, angiogenesis, and reduction of blood levels of matrix metalloproteinases-1 and -3.

194 ted by changes in symptoms, side effects, or blood levels of medications.

195 mined the associations between prediagnostic blood levels of micronutrients and prostate cancer risk

196 We found an inverse relationship between blood levels of MIR122 and EPO in mice with acute pancre

197 ound that LPS-induced inflammation increases blood levels of MIR122, which reduces expression of Epo

198 r response, pharmacokinetics, and changes in blood levels of MMP-2, MMP-9, vascular endothelial growt

199 ELISAs demonstrated that blood levels of mouse insulin were higher in the hMSC-tr

200 The blood levels of natural killer cells were not altered in

201 evels, suggesting a link between MC load and blood levels of NGF and NT-4.

202 h SCZ had significantly decreased peripheral blood levels of NGF when compared with the HC subjects (

203 Similarly, blood levels of nitric oxide were much higher in fatal c

204 of hemoglobin and arginase-1, reduced whole-blood levels of nitrite, and increased NO consumption re

205 Notably, blood levels of NKp46 were also decreased in prostate ca

206 The ability to monitor and manipulate blood levels of NO, in conjunction with O(2) and carbon

207 y weight, smaller epididymal fat pads, lower blood levels of nonesterified fatty acids and triglyceri

208 ly higher infiltrating T-cells and increased blood levels of numerous cytokines.

209 nt also elongated the estrous cycle, reduced blood levels of progesterone, and eliminated lordosis be

210 rt of the specificity of these associations, blood levels of quinolinic acid were unrelated to striat

211 Blood levels of R333 at 2 and 24 hr were consistently 10

212 Blood levels of R348 and of its active metabolite R333 w

213 Blood levels of radioactivity, antibodies, shed serum HE

214 The blood levels of reproductive hormones were mostly normal

215 Moreover, blood levels of S1P were higher in mice with colon cance

216 Fourth, we show that the blood levels of SAT1 (spermidine/spermine N1-acetyltrans

217 Fetal cord blood levels of sCD14, LBP, and IL-6 were determined.

218 AVNFH patients also had elevated blood levels of sodium and creatinine, and reduced level

219 ave shown an association between circulating blood levels of some insulin-like growth factors (IGFs)

220 n implicated in prostate carcinogenesis, and blood levels of specific saturated fatty acids (SFAs) an

221 gest that patients who are exposed to higher blood levels of tacrolimus are at higher risk of viral r

222 Blood levels of tamoxifen were 81% higher in postmenopau

223 We measured peripheral blood levels of TCR rearrangement excision circles (TREC

224 of animals evaluated and the variability in blood levels of TDF that resulted from oral dosing.

225 t in vivo, TEMPOL/PNA maintains redox-active blood levels of TEMPOL for almost 5 h, whereas administr

226 The associations between AP and blood levels of TG, CHOL, and anti-P. gingivalis whole c

227 nvestigated but ultimately dismissed because blood levels of thallium, although raised, were lower th

228 Elevated peripheral blood levels of the CXCR3 chemokine ITAC/CXCL11 are asso

229 erty, and which produced clinically relevant blood levels of the drug, impaired pubertal testicular d

230 the hydroxychloroquine group had detectable blood levels of the drug.

231 due to the ability of these drugs to elevate blood levels of the hormone prolactin, the mechanism for

232 Additionally, NADA reduces blood levels of the neuropeptide calcitonin gene-related

233 folate, and alpha-tocopherol in relation to blood levels of these nutrients.

234 acid, with the combined free and esterified blood levels of these two fatty acid derivatives exceedi

235 oint-of-care test for instant monitoring the blood levels of this blockbuster anticoagulant drug in s

236 7 DJ-1 isoforms were reliably detected, and blood levels of those with 4-hydroxy-2-nonenal modificat

237 bsent in affected males, the disturbances in blood levels of thyroid hormones suggest the possibility

238 both in vitro and in vivo and that elevated blood levels of TNFalpha are observed in obese and/or di

239 MGD was significantly associated with higher blood levels of total cholesterol (OR, 1.07; 95% confide

240 d women that have examined dietary intake or blood levels of total or individual carotenoids with the

241 clinical suspicion of NET (n = 70), elevated blood levels of tumor markers (n = 49), and image-based

242 These changes were accompanied by increased blood levels of tumor necrosis factor alpha (TNF-alpha)

243 an effective analytical method to determine blood levels of two major beta-carboline derivatives, ha

244 Blood levels of uric acid, creatinine, phosphorus, and p

245 eline tumor vessel permeability and elevated blood levels of vascular endothelial growth factor D and

246 Blood levels of VEGF-A165b were significantly higher in

247 An assessment of the blood levels of virus indicated 17.5% of the samples (n

248 Blood levels of vitamin C and E, beta-carotene, and sele

249 We conclude that oleic acid, the blood levels of which vary among individuals, is at leas

250 It has been shown that diets and blood levels of women who had a fetus with a neural tube

251 xposure to tobacco smoke, where smokers have blood levels on average up to eight times higher than no

252 In one recipient with subtherapeutic RAD blood levels on day 7 posttransplant, exogenous insulin

253 phisms (SNPs) with melanoma patient IL-12p40 blood levels or their potential contributions to melanom

254 sting for substantial differences in ghrelin blood levels over time and between treated and untreated

255 oglycemic episode, falling to 10 +/- 1.2% of blood levels (P < 0.01).

256 4746 (Gly32Ala), was associated with IGFBP-3 blood levels (P(adj) = 8.8 x 10(-43)) after adjusting fo

257 was administered during ischemia to generate blood levels ranging from 5.9 +/- 1.8mM (normoglycemia)

258 a characteristic loading phase during which blood levels rapidly rise and then are maintained within

259 und pharmacodynamic effects long after their blood levels reach zero.

260 e.g., lung) at a single granuloma scale with blood level readouts that can be tracked in monkeys and

261 ed albumin (IMA; Ischemia Technologies, Inc) blood levels rise in patients who develop ischemia durin

262 a novel IGF1 SNP, not associated with IGF-I blood levels, shows preliminary evidence for association

263 Detectable blood levels strongly correlated with the prophylactic e

264 ng of psychopharmacological side effects and blood levels than comparable patients on a general psych

265 Myopathy is more related to statin dose and blood levels than to LDL reductions.

266 erproduction was reflected by elevated IL-19 blood levels that correlated with psoriasis severity.

267 duced serotonin (5-hydroxytryptamine (5-HT)) blood levels that paralleled a mild bleeding phenotype i

268 Subjects in the top decile of FFQ intake had blood levels that were 27% (lycopene) to 178% (beta-cryp

269 peutic cyclosporine (CSA) or tacrolimus (FK) blood levels, the incidence of rejection decreased signi

270 ated with hyperinsulinemia and increased FFA-blood levels, the interplay between insulin and FFA was

271 ion therapy with basiliximab enabled SDZ RAD blood levels to be significantly reduced, which led to i

272 systemically after predetermination of their blood levels to ensure bioavailability at an appropriate

273 leles associated with lipid levels and other blood level traits.

274 d on Day -2, was maintained with tapering of blood levels until full withdrawal at 6 months.

275 etes, donor source, and induction agent, TAC blood level was associated with increased risk of BKN (o

276 circulation; at 30 min after injection, the blood levels were 0.44 +/- 0.28 %ID/g.

277 ter polymorphism A-202C (rs2854744); IGFBP-3 blood levels were 6.3% higher for each minor allele.

278 Target SRL blood levels were 8 to 12 ng/mL.

279 TG was stopped once therapeutic cyclosporine blood levels were achieved.

280 IL-12p40 blood levels were assessed among 573 cases (discovery),

281 umor necrosis factor-alpha and interleukin-6 blood levels were both lower in those who received E5531

282 Of the women in the 4400-IU group whose blood levels were checked, 289 (74.9%) had 25-hydroxyvit

283 tacrolimus targeted to relatively low trough blood levels were compared with those of a concurrent gr

284 levels by 30 min and 3 hr, respectively, and blood levels were constantly higher than plasma.

285 Sirolimus trough blood levels were correlated with efficacy.

286 rates and nitrites, octreotide, and glucagon blood levels were determined at baseline and after each

287 Troponin I blood levels were determined before and 2 to 10 hours af

288 VPA blood levels were higher in responders (P < .005).

289 Average steady state blood levels were low (71 +/- 30 ng/ml), and associated

290 In both animals, SDZ RAD blood levels were more than 5-fold higher than under mon

291 BCNU blood levels were obtained before and after polymer impl

292 Higher CD19(+) blood levels were positively associated with MM-patient

293 Eicosapentaenoic and docosahexaenoic acid blood levels were significantly higher in the prescripti

294 Blood levels were within the normal range.

295 and reduced NT-probrain natriuretic peptide blood level when compared with the initial evaluation.

296 on examination of their steady-state tissue/blood levels, which result from a combination of tissue

297 A recent study showed that reduced GDF11 blood levels with aging was associated with pathological

298 ubjects, a sex-specific association of PACAP blood levels with fear physiology, PTSD diagnosis and sy

299 Compared with NaPBA, peak metabolite blood levels with GPB occurred later and were lower; uri

300 ation has identified association of IL-12p40 blood levels with melanoma recurrence and patient surviv