ライフサイエンスコーパス: blood meal

1 mit the Plasmodium sporozoite stage during a blood meal.

2 complete their first ovarian cycle without a blood meal.

3 port oogenesis without the requirement for a blood meal.

4 quitoes, increases dramatically soon after a blood meal.

5 of miR-x2 level was observed 72 hrs after a blood meal.

6 increases in the midgut and fat body after a blood meal.

7 uent spirochete transmission during a second blood meal.

8 d with that of the virus administered in the blood meal.

9 es prior to ingestion by a mosquito during a blood meal.

10 npredictable moment, when a mosquito takes a blood meal.

11 or the activation of egg development after a blood meal.

12 es were ingested by the parasites with their blood meal.

13 nsects seem unaffected by the iron load in a blood meal.

14 preventing activation of this gene before a blood meal.

15 and the target YPP gene Vg, in response to a blood meal.

16 genous mosquitoes, egg maturation requires a blood meal.

17 tive cycle and is activated in response to a blood meal.

18 competing with the tick for nutrients in the blood meal.

19 transgenic mosquitoes from 8 to 24 h after a blood meal.

20 trate the peritrophic matrix surrounding the blood meal.

21 burgdorferi vlsE locus before and during the blood meal.

22 ody tissues of female mosquitoes following a blood meal.

23 cted the host at time points >53 hr into the blood meal.

24 ch presumably assists the fly in obtaining a blood meal.

25 ese antisera were ingested with the infected blood meal.

26 the key event in egg maturation, requires a blood meal.

27 was strongly activated in the fat body by a blood meal.

28 in the fly during excretion of the digested blood meal.

29 nother mammalian host during the tick's next blood meal.

30 ining envelope that completely surrounds the blood meal.

31 is likely primed by bacterial growth in the blood meal.

32 same Vmp present in the previous infectious blood meal.

33 e as well as a lipopolysaccharide-containing blood meal.

34 inogen activators were derived from the host blood meal.

35 throcytes of the vertebrate and the mosquito blood meal.

36 after infection with a LAC virus-containing blood meal.

37 ntibodies in the host as well as in the tick blood meal.

38 tor Aedes aegypti, which acquires ZIKV via a blood meal.

39 sion rates in vivo when administered via the blood meal.

40 native microbiota proliferates, following a blood meal.

41 chetes against threats engendered during the blood meal.

42 ing either component is destroyed during the blood meal.

43 amino acids between mosquito tissues after a blood meal.

44 ding Anopheline mosquito midguts following a blood meal.

45 l site of viral infection after an infective blood meal.

46 acted to human body heat during pursuit of a blood meal.

47 dgut tissue after ingestion of an infectious blood meal.

48 roxy) and resistance to starvation without a blood meal.

49 enetration into the tick body or through the blood meal.

50 hemoglobin, were preserved in the fossilized blood meal.

51 sweat to select humans as their source for a blood meal.

52 h were subsequently fed with Leishmania in a blood meal.

53 ferent immune evasion strategies to obtain a blood meal.

54 t in human sweat to locate their hosts for a blood meal.

55 emperature stress incurred by drinking a hot blood meal.

56 hours over the course of their up to 96 hour blood meals.

57 when ingested by Anopheles mosquitoes during blood meals.

58 nfection when fed on patient-derived viremic blood meals.

59 was reduced, and those feeding took smaller blood meals.

60 mosquitoes to adapt in order to obtain human blood meals.

61 for survival during both larval and nymphal blood meals.

62 varies of mosquitoes that took an additional blood meal 30 days p.i. and was continuous in mosquitoes

63 Identified blood meals (30%) were from 20 vertebrate species includ

64 cript abundances at five time points after a blood meal, a key event in both reproduction and disease

65 ion to facilitating long-term attachment and blood meal acquisition, gene expression studies of Droso

66 associated inflammation, allowing successful blood-meal acquisition from hosts.

67 , five of which are possibly associated with blood-meal acquisition, each having cDNA similarity to:

68 tical importance of microRNAs in controlling blood-meal-activated physiological events required for c

69 we uncovered another essential regulator of blood-meal-activated processes, the microRNA miR-275.

70 s transcribed at a very high level following blood meal activation.

71 s of mosquitoes that did not receive further blood meals after their original oral infection.

72 After an infectious blood meal, AgTreT1 RNA silencing reduces the number of

73 s, carbohydrates, and fatty acids during the blood meal among the three groups of nymphal ticks sugge

74 es the activation of egg development after a blood meal, an adaptation to the unique life style of mo

75 factor (AaGATAa) that is synthesized after a blood meal and acts as a transcriptional activator of Vg

76 is robust against random degradation of the blood meal and can identify unknown blood remnants month

77 lly synthesize in the tick vector during the blood meal and down-regulate after transmission to the m

78 c activities that promote acquisition of the blood meal and enhance infection with pathogens.

79 may be occurring during the digestion of the blood meal and not afterwards.

80 heir role in intracellular processing of the blood meal and response to microbial infections.

81 are released from the brain in response to a blood meal and stimulate the ovaries to secrete ecdyster

82 tes and their critical interactions with the blood meal and the mosquito vector.

83 ear how Plasmodium or other pathogens in the blood meal and their invasion of the midgut epithelium w

84 n occur after adult female mosquitoes take a blood meal and use the nutrients for egg maturation.

85 0) exclusively during the larval and nymphal blood meals and (ii) that transcription of bba74 is brac

86 based on the ecological context of mosquito blood meals and the fine-scale movements of individual m

87 g both ookinete development (day 1 after the blood meal) and oocyst maturation (day 7 after the blood

88 ed to incorporate components from the flea's blood meal, and bacteria released from the biofilm were

89 reased mRNA abundance in females following a blood meal, and those accumulating transcription product

90 in powder, including six peptides for bovine blood meal; and one peptide for porcine blood.

91 The model takes a mosquito's blood meal as input and computes the salivary gland spor

92 tic disease, is transmitted during a sandfly blood meal as the parasite is delivered into the dermis.

93 ellow fever mosquito, Aedes aegypti, seeking blood-meals as well as oviposition sites.

94 ene was induced on day 2 after an infectious blood meal, at the time of ookinete to oocyst differenti

95 activation and replication during the tick's blood meal before it is able to infect a host.

96 OspD continues during tick digestion of the blood meal but is low or undetectable after the tick has

97 ession of rpoS is induced during the nymphal blood meal but not within unfed nymphs or engorged larva

98 meal) and oocyst maturation (day 7 after the blood meal) but not during sporozoite invasion of the sa

99 raerythrocytic gametocytes are taken up in a blood meal by a mosquito they emerge as gametes and, onc

100 y where blood and microbes ingested with the blood meal come in contact with the tick's internal tiss

101 cretion has been shown as important for both blood-meal completion and pathogen transmission.

102 ting', prolonged feeding, cuticle synthesis, blood meal concentration, novel methods of haemoglobin d

103 to-borne parasite faces when ingested with a blood meal; consequently, understanding the biology of P

104 fects Aedes aegypti mosquitoes that ingest a blood meal containing 8 to 9 log(10) PFU of virus/ml.

105 of the duration of human infectiousness, and blood meals containing high concentrations of DENV were

106 he number of eggs oviposited after the first blood meal decreases with age in all strains; however, t

107 esent work elucidates the molecular basis of blood meal-dependent expression of this mosquito gene, l

108 Tissue-specific expression and blood meal-dependent regulation of Slif are consistent w

109 Host complement in the tick's blood meal did not contribute to protection because the

110 in midgut transcripts in the sand fly during blood meal digestion and that this modulation may be rel

111 that D. variabilis KPI may be important for blood meal digestion in the midgut.

112 aegypti females, the ammonia released during blood meal digestion is partially metabolized to facilit

113 s have to survive the hostile environment of blood meal digestion, escape the blood bolus and attach

114 as proteins putatively directly involved in blood meal digestion, including enzymes involved in oxid

115 ver mosquito Aedes aegypti to interfere with blood meal digestion.

116 ts relevant to the processes associated with blood-meal digestion were analysed and involvement of se

117 investigating the role of the tick midgut in blood-meal digestion, antimicrobial activity or the tran

118 lease of detectable virus particles into the blood meals during feeding events.

119 Our study reveals that blood meals enhance arbovirus replication in mosquitoes

120 mixed population was exposed to an infected blood meal every generation, allele frequencies at the Q

121 Adult females of the genus Ixodes imbibe blood meals exceeding about 100 times their own weight w

122 promastigotes to persist in the midgut after blood meal excretion was completely lost, and this defec

123 cell membrane integrity, stimulate premature blood meal excretion, and block induced expression of se

124 atrix formed inside the midgut lumen after a blood meal feeding.

125 bolic capacity, spirochetes rely on the tick blood meal for nutrients and metabolic intermediates whi

126 Female mosquitoes require a blood meal for reproduction, and this blood meal provide

127 their obligatory requirement of a vertebrate blood meal for reproduction, these mosquitoes need a lot

128 o Anopheles spp. mosquitoes when they take a blood meal from a host that has recently received one of

129 ature increases dramatically when it takes a blood meal from a warm-blooded, vertebrate host.

130 hen B. burgdorferi-infected ticks take their blood meal from an immunized host.

131 When the tsetse takes a blood meal from an infected human, it ingests bloodstrea

132 etitive PCR, we found that ticks ingesting a blood meal from B-cell-deficient mice, which lack all im

133 Most of ovaries 24 h post second blood meal from iHR3 females in the second cycle were sm

134 cks are responsive to IFNgamma acquired in a blood meal from mice infected with the Lyme disease-caus

135 rvive within Ixodes scapularis ticks after a blood meal from naive mice; however, ticks infected with

136 The ability of C. quinquefasciatus to take blood meals from birds, livestock, and humans contribute

137 Here, we investigated whether blood meals from hematophagous flies could be used to id

138 transmission by killing mosquitoes that take blood meals from IVM-treated humans.

139 g sugar feeding, blood feeding and after the blood meal has been processed and excreted, both in the

140 range of environmental sources, most notably blood meal hosts and oviposition sites.

141 as also enhanced when MyD88-/- mice were the blood meal hosts, with the mean pathogen burden at the s

142 ived chemical kairomones in their search for blood meal hosts.

143 ough many species of mosquitoes never take a blood meal, identifying genes that distinguish blood fee

144 ogens by mosquitoes relies on their taking a blood meal; if there is no bite, there is no disease tra

145 gametocytes within a newly ingested infected blood meal in the mosquito midgut emerge from erythrocyt

146 ic matrix (PM), which surrounds the infected blood meal in the mosquito midgut.

147 ontaining peritrophic matrix surrounding the blood meal in the mosquito midgut.

148 changes that spirochetes undergo following a blood meal in the tick.

149 effectively disrupts egg development after a blood meal in vivo.

150 ly increases in fat body and ovaries after a blood meal in vivo.

151 lbachia strain in A. gambiae, and alleviated blood meal-induced mortality in A. stephensi enabling pr

152 phensi, Wolbachia infection elicited massive blood meal-induced mortality, preventing development of

153 achia transmission and partly contributed to blood meal-induced mortality.

154 in sub-Saharan Africa, were fed with either blood meal infected with R. felis or infected cellular m

155 MUC1 RNA abundance decreased with time after blood meal ingestion.

156 to activate vitellogenesis in response to a blood-meal-initiated, elevated titer of 20-hydroxyecdyso

157 peritrophic matrix (PM) that forms around a blood meal is a potential barrier of Plasmodium developm

158 lacking OspA is increased when the infecting blood meal is derived from mice that do not produce anti

159 indicating that the oxidative stress after a blood meal is exacerbated by Plasmodium infection.

160 xpression of hsp70, protein digestion of the blood meal is impaired, leading to production of fewer e

161 In hematophagous insects, the blood meal is important for regulating egg maturation.

162 In anautogenous mosquitoes, a blood meal is required for activation of genes encoding

163 A vertebrate blood meal is required for egg production, and multiple

164 ls, similar to the increase observed after a blood meal, is critical for 20E stimulation of YPP gene

165 rotein C (OspC), which is induced during the blood meal, is critical for transmission of Lyme disease

166 response, elicited by the temperature of the blood meal, is most robust in the mosquito's midgut.

167 Based on 25 blood-meals, mammalian feeding suggests a potential brid

168 t of rapamycin (TOR) pathways in controlling blood-meal-mediated egg maturation in mosquitoes.

169 Eleven days after a Plasmodium-infected blood meal, mosquitoes were treated with M. anisopliae e

170 that reducing the gametocyte density in the blood meal most significantly lowers sporozoite load in

171 During the blood meal, multiple vlsE alleles were observed in the t

172 ication of the species from which a previous blood meal of a hematophagous arthropod was taken is ach

173 the human bloodstream are taken up with the blood meal of the mosquitoes and inactivate parasite dev

174 and further development when taken up in the blood meal of tsetse flies, the vector for trypanosomias

175 technique designed to identify the source of blood meals of haematophagous arthropods.

176 bers, as well as a proportional shift in the blood meals of ticks away from deer.

177 ly acquired Dps-deficient spirochaetes via a blood meal on mice.

178 no acids, fatty acids and nucleosides from a blood meal or various host tissues.

179 into mechanisms by which ookinetes exit the blood meal, penetrate and transverse the peritrophic mat

180 ase inhibitor, allosamidin, in an infectious blood meal prevents oocyst development.

181 of allosamidin, a chitinase inhibitor, in a blood meal prevents the parasite from invading the midgu

182 the molecular mechanisms linked to mosquito blood meal processes and reproductive events is of parti

183 e that this boost in temperature following a blood meal prompts the synthesis of heat shock protein 7

184 uire a blood meal for reproduction, and this blood meal provides the underlying mechanism for the spr

185 ngal entomopathogens following an infectious blood meal reduced the number of mosquitoes able to tran

186 ting mosquitoes after oral feeding of spiked-blood meals, representing an additional safety feature.

187 ted salivary glands 14 and 18 days after the blood meal, respectively.

188 h activates ERK in the mosquito gut during a blood meal, restricts viral infection in Drosophila cell

189 by spirochete populations during the nymphal blood meal results from the intricate sequence of transc

190 e addition of MAbs 1A6 and 2B5 to infectious blood meals significantly inhibited oocyst development i

191 owever, no differences in feeding success or blood meal size were found in membrane feeding experimen

192 x O (FOXO) and p70 S6 kinase in a tissue and blood meal-specific manner.

193 To that end, we have developed a blood meal substitute specifically for mosquitoes infect

194 One example is the lack of a blood meal substitute, which accounts for the Wolbachia-

195 eeding ticks that were infected prior to the blood meal suggests that this surface protein is involve

196 Mosquitoes were fed a blood meal supplemented with [1,2-(13)C2]glucose, and do

197 We next exposed females to blood meals supplemented with allopurinol, a well-charac

198 f Borrelia burgdorferi sensu lato to survive blood meals taken by ticks feeding on birds were analyze

199 n nymph tick survival following the insect's blood meal than before.

200 approximately fivefold more eggs following a blood meal than through autogeny, we suggest that the ma

201 oreover, when incorporated into an infective blood meal, the antitrypsin antibodies blocked infectivi

202 Before the blood meal, the bacteria in the tick were a homogeneous

203 Within hours after the ingestion of a blood meal, the mosquito midgut epithelium synthesizes a

204 During the blood meal, the population became more heterogeneous; ma

205 After a blood meal, the subcellular localization of TOR shifts f

206 ue to active dispersal by mosquitoes seeking blood meals, there was no statistical basis for choosing

207 merous viral diseases, because it requires a blood meal to facilitate egg development.

208 strategy, termed anautogeny, that requires a blood meal to initiate egg maturation.

209 The majority of mosquito species require a blood meal to stimulate vitellogenesis and subsequent ov

210 sone is a key regulatory factor, controlling blood-meal triggered egg maturation in mosquitoes.

211 mic immunity, which is activated through the blood meal-triggered cascade rather than by infection.

212 at genes encoding enzymes needed to digest a blood meal (trypsin and a chymotrypsin-like protease) ar

213 e expressed as the female prepares to take a blood meal upon the termination of diapause.

214 itical antibody-shielding role during vector blood meal uptake from immune hosts and is not required

215 smodium developmental stages in the mosquito blood meal using the rodent malaria parasite Plasmodium

216 Comparison of infection via the blood meal versus intrathoracic injection, which bypasse

217 lase captures plasminogen from the mammalian blood meal via its lysine motif (DKSLVK) and that this i

218 ing the source of the remnants of a previous blood meal via shotgun proteomics and spectral matching.

219 Midguts, dissected 48 hr after an infected blood meal, were used to prepare two RNA bulks, each rep

220 a narrow window time at the beginning of the blood meal when antibodies bind to OspA-expressing spiro

221 y in the midgut within the first 48 h of the blood meal, when ticks acquire infection.

222 Among them are blood products and blood meal, which are used as high-quality material for

223 d by an insect vector during the taking of a blood meal, which directly links nutrient acquisition an

224 ars to have perished immediately following a blood meal, which may have been from coexisting mammals,

225 s contributes to arboviral infection after a blood meal, which suppresses antiviral innate immunity b

226 ambiae gut leading to the utilization of the blood meal will result in a deeper understanding of the