ライフサイエンスコーパス: blood neutrophil

1 transporters, SLC and ABC, in resting human blood neutrophils.

2 8), enabling them to recruit APRIL-producing blood neutrophils.

3 nd PU.1 proteins in the patient's peripheral blood neutrophils.

4 ease in the production of IL-8 by peripheral blood neutrophils.

5 sorders, resulting in the lack of peripheral blood neutrophils.

6 without dexamethasone to mobilize peripheral blood neutrophils.

7 n of LPS to the inhibitory effect of GC-w on blood neutrophils.

8 o be cell type-dependent and is cytosolic in blood neutrophils.

9 e by finding ehrlichia morulae in peripheral blood neutrophils.

10 rated morulae in the cytoplasm of peripheral blood neutrophils.

11 from ex vivo-isolated G-CSF-mobilized human blood neutrophils.

12 treatment decreased Glut1 and PiT2 levels in blood neutrophils.

13 ced l-selectin shedding and rise in CD11b of blood neutrophils.

14 Obese patients had significantly higher blood neutrophils.

15 ondensed chromatin in HL-60 granulocytes and blood neutrophils.

16 many eukaryotic cells, regulate polarity of blood neutrophils?

17 ular hydrogen peroxide content in peripheral blood neutrophils 5 hrs after burn.

18 In resting human and rat peripheral blood neutrophils, 5-LO is localized to the cytoplasm; i

19 erized by extremely low levels of peripheral blood neutrophils, a maturation block of bone marrow pro

20 We show that fetal blood neutrophils acquire the ability to roll and adhere

21 ere significantly correlated with peripheral blood neutrophil activation patterns (r = 0.75, p = 0.00

22 receptor usage, and differential peripheral blood neutrophil activation that could contribute to HCM

23 ear 5-lipoxygenase was also evident in human blood neutrophils after adherence to a variety of surfac

24 Comparison of peripheral blood neutrophils after completion of 5 weekly treatment

25 and MEK1/2 were not activated in peripheral blood neutrophils after hemorrhage or endotoxemia.

26 nding protein were activated in lung but not blood neutrophils after hemorrhage or endotoxemia.

27 to upregulate CD18 expression on peripheral blood neutrophils also appeared in milk at this time.

28 itatively similar to UV-irradiated apoptotic blood neutrophils, although the signaling pathway for th

29 e characterized by an increase in peripheral blood neutrophils, an increase in myeloid progenitor pop

30 rtmentalize TLR4 signaling, we characterized blood neutrophil and cytokine responses, NF-kappaB1 acti

31 e, Prg4 mutant mice had increased peripheral blood neutrophils and decreased marrow B220(+) (B-lympho

32 Blood neutrophils and eosinophils were isolated on 2 sep

33 ponent-specific antibody in human peripheral blood neutrophils and HL-60 cells.

34 an autoperfused flow chamber assay of whole blood neutrophils and intravital microscopy of the infla

35 ents showed prompt leukocytosis with maximum blood neutrophils and lymphocytes at 6-12 hours.

36 Analysis of blood neutrophils and monocytes and a microglial cell li

37 tively with FR-beta expression in peripheral blood neutrophils and monocytes and also in KG-1 (AML) c

38 CLECSF8 is primarily expressed by peripheral blood neutrophils and monocytes and weakly by several su

39 In septic peritonitis, blood neutrophils and monocytes are rapidly recruited in

40 in L-selectin expression on both peripheral blood neutrophils and monocytes but has no effect on lym

41 ee mice showed reduced numbers of peripheral blood neutrophils and monocytes.

42 gene transcripts in unstimulated peripheral-blood neutrophils and mononuclear cells from patients wi

43 Only blood neutrophils and myeloid cell lines expressed this

44 iC1INH enhanced the bactericidal activity of blood neutrophils and peritoneal exudate leukocytes.

45 fluid and accelerated killing of bacteria by blood neutrophils and peritoneal macrophages.

46 In this study, we used human peripheral blood neutrophils and transfected cells expressing alpha

47 is important for resistance of GBS to human blood, neutrophils and oxidative stress.

48 With HL-60 cells, fresh human peripheral blood neutrophils, and a cell line devoid of the fucosyl

49 and CD8 T-cell responses, CMV viral load in blood neutrophils, and allograft rejection during the fi

50 etention of Ox nucleoids is a feature of SLE blood neutrophils, and autoantibodies against Ox mtDNA a

51 due to a failure of bone marrow progenitors, blood neutrophils, and bronchoalveolar lavage cells to i

52 In this study, we examined peripheral blood neutrophil apoptosis and showed it to be accelerat

53 Alveolar and blood neutrophil apoptosis, phagocytosis, and adhesion m

54 d spleen; however, the numbers of peripheral blood neutrophils appear to be independently modulated a

55 Alveolar macrophages are primed and blood neutrophils are down-regulated for production of M

56 Healthy blood neutrophils are functionally quiescent in the bloo

57 Quantitative measurements of C5aR on blood neutrophils are highly predictive of survival or d

58 ore often nasal polyps, and higher levels of blood neutrophils as compared to patients who experience

59 or extracellular release by human peripheral blood neutrophils, as measured by a luminol-dependent ch

60 -C chemokine receptors 2 and 4 on peripheral blood neutrophils, as well as actin polymerization and m

61 rbol myristate acetate-stimulated peripheral blood neutrophils at 4 weeks and 2.6% +/- 1.0% at 14 wee

62 These glycolipids are expressed on human blood neutrophils at densities exceeding those required

63 r by pharmacologic means in human peripheral blood neutrophils attenuated phagocytosis of opsonized K

64 cytes from the thymus and spleen, peripheral blood neutrophils began to recover within 24 hours after

65 Blood neutrophils can be stimulated to express and rapid

66 s for the first time that drastic changes in blood neutrophils can originate from alternative reservo

67 nd restoration of innate immune functions of blood neutrophils (chemotaxis and reactive oxygen specie

68 The aim is to review normal blood neutrophil concentrations and the clinical approac

69 This study investigated whether peripheral blood neutrophil concentrations in these mice are elevat

70 Here, we show that all blood neutrophils constitutively secrete APRIL, and infl

71 In contrast to these results, peripheral blood neutrophils contained both leukotriene A(4) hydrol

72 activated human CD4(+) or CD8(+) T cells, or blood neutrophils, could be demonstrated.

73 ion and sham groups in the mean increment in blood neutrophil count at 8 hours (6.16 x 10(9)/L and 6.

74 take was sustained longer than the period of blood neutrophil count elevation.

75 and independently associated with peripheral blood neutrophil count in contacts of patients diagnosed

76 bone marrow was enhanced, and the peripheral blood neutrophil count was also substantially elevated i

77 The blood neutrophil count was modestly elevated.

78 E-selectin, TNFalpha, and MPO and peripheral blood neutrophil count were higher in patients with RA t

79 ay mortality and biomarkers of inflammation (blood neutrophil count, urea, and creatinine concentrati

80 ric oxide levels (38 vs 27 ppb, P = .02) and blood neutrophil counts (5.3 vs 4.0 10(9)/L, P </= .001)

81 and whether age, FEV1 percent predicted, and blood neutrophil counts accurately predict sputum neutro

82 Blood neutrophil counts also increased during G-CSF (med

83 ounts in alveolar air spaces, despite normal blood neutrophil counts and survival of emigrated neutro

84 Blood neutrophil counts are determined by the differenti

85 Recovery occurred even though blood neutrophil counts began to rise 48 hours after the

86 We conclude that IL-17A regulates blood neutrophil counts by inducing G-CSF production mai

87 Likewise, age, asthma duration, and blood neutrophil counts correctly predicted 64% of sputu

88 It also elevated peripheral blood neutrophil counts in mice.

89 Blood neutrophil counts in patients receiving these larg

90 relevant to maintain the normal set point of blood neutrophil counts in vivo.

91 ges, whereas age, FEV1 percent predicted, or blood neutrophil counts might predict sputum neutrophil

92 Blood neutrophil counts were elevated (4.8x), whereas ly

93 Age, FEV1 percent predicted, and blood neutrophil counts were similarly unsatisfactory fo

94 is brief review summarizes the regulation of blood neutrophil counts, which is in part controlled by

95 cells had the greatest effects on regulating blood neutrophil counts.

96 with the clinical symptoms of arthritis and blood neutrophil counts.

97 In human peripheral blood neutrophils, cross-linking of L-selectin induced a

98 Peripheral blood neutrophils cultured with 50% RA synovial fluid we

99 Peripheral blood neutrophils derived from 24 hours post-hemorrhage,

100 and integrin expression on human peripheral blood neutrophils, despite differences in affinity for t

101 Like blood neutrophils, dHL60 cells respond to a uniform conc

102 but that before embryonic day (E) 15, fetal blood neutrophils display little ability to roll or adhe

103 lopment of MOF and the accompanying onset of blood neutrophil dysfunction.

104 e marrow and highly significant increases in blood neutrophils, eosinophils, and basophils.

105 Freshly isolated human peripheral blood neutrophils exhibited relatively low plasminogen b

106 Human and murine peripheral blood neutrophils expressed HIF-2alpha, with expression

107 ignificant decrease in marrow and peripheral blood neutrophils, far greater than that seen in either

108 These observations suggest that decreased blood neutrophil FcgammaRIII expression without increase

109 Similar changes could be induced in vitro on blood neutrophils following contact with phorbol ester o

110 ted in up to approximately 80% of peripheral blood neutrophils for at least 28 to 35 weeks after tran

111 ent delays the apoptosis of human peripheral blood neutrophils for its advantage, peripheral blood gr

112 Peripheral blood neutrophils form highly decondensed chromatin stru

113 Compared with peripheral blood neutrophils from +/+ mice, db/db neutrophils demon

114 rescence in situ hybridization in post-G-CSF blood neutrophils from 4 of 6 patients but was also pres

115 PP2A activity was measured in peripheral blood neutrophils from A1AT-deficient (PiZZ) and healthy

116 yS was detected on the surface of peripheral blood neutrophils from both RA patients and healthy cont

117 expression nor glucose uptake was altered on blood neutrophils from CF patients compared with healthy

118 Blood neutrophils from CLP rats demonstrated defective p

119 Freshly isolated peripheral blood neutrophils from controls did not express surface

120 utrophils from control mice or in peripheral blood neutrophils from endotoxemic, hemorrhaged, or cont

121 Peripheral blood neutrophils from human immunodeficiency virus-nega

122 BAL and blood neutrophils from infants with RSV disease, but not

123 proteins and mRNA transcripts within BAL and blood neutrophils from infants with severe RSV bronchiol

124 Peripheral blood neutrophils from mature animals killed B. dermatit

125 erized by remarkably regular oscillations of blood neutrophils from near normal to extremely low leve

126 Peripheral blood neutrophils from normal mice strongly expressed A1

127 Peripheral blood neutrophils from patients (n = 19), before and 3 m

128 take of whole virus; 17 of 20 BAL and 8 of 9 blood neutrophils from patients expressed RSV N mRNA.

129 Peripheral blood neutrophils from patients with RA but not healthy

130 Freshly isolated peripheral blood neutrophils from patients with RA expressed mRNA,

131 In peripheral blood neutrophils from rats, 5-lipoxygenase was exclusiv

132 (IEC-18) were carried out in the presence of blood neutrophils from sham, B, EF, or B+EF rats.

133 production because peritoneal and peripheral blood neutrophils from uninfected animals contained IL-1

134 Peripheral blood neutrophils from untreated septic animals and sept

135 ecific response, we used isolated peripheral blood neutrophils from wild-type or CD18-null mice and s

136 The migratory accuracy of blood neutrophils from young (aged <35 yr) and old (aged

137 Peripheral blood neutrophils from young pigs expressed PR-39 and pr

138 eling in healthy humans is consistent with a blood neutrophil half-life of less than 1 day.

139 il production without significantly altering blood neutrophil half-life or margination.

140 centration of A23187 for activation than did blood neutrophils (half-maximal response, 160 versus 52

141 on of NF-kappaB in LPS-stimulated peripheral blood neutrophils has been shown to be associated with m

142 Blood neutrophil homeostasis is essential for successful

143 RSV proteins were found in BAL and blood neutrophils in infants with RSV disease but not in

144 duce OSM production (P < .001) in peripheral blood neutrophils in vitro.

145 Blood neutrophils increased from preexposure (34.4% +/-

146 the beta(1) and beta(2) integrin content on blood neutrophils increased in a nontranscriptional mann

147 ith higher BMI (P = 0.03), and the number of blood neutrophils increased less in obese than in lean p

148 In this study, peripheral blood neutrophils incubated with RSV (multiplicity of in

149 ated with reduced infiltration of peripheral blood neutrophils into infarcted tissue and with impaire

150 ecies production between oral and peripheral blood neutrophils isolated from patients with chronic pe

151 Whereas blood neutrophil levels and LPS-elicited tissue neutroph

152 During these events, blood neutrophils lost their chemotactic responsiveness

153 tly higher, and the percentage of peripheral blood neutrophils lower, in infected IL-3 KO mice than i

154 Menin loss modestly impaired blood neutrophil, lymphocyte, and platelet counts.

155 gnificantly, delayed apoptosis of peripheral blood neutrophils (mean suppression 45.7% +/- SD 22.3).

156 blood neutrophils (PBNs) or mouse peripheral blood neutrophils (MPBNs) but markedly greater than did

157 Like mature peripheral blood neutrophils, myeloblasts expressed glucosylceramid

158 Thus, PSGL-1 is expressed on essentially all blood neutrophils, NK cells, B cells, T cells, and monoc

159 Human blood neutrophils normally express two FcgammaRs (Fcgamm

160 These data show that peripheral blood neutrophil numbers are regulated by a feedback loo

161 Although blood neutrophil numbers in inbred mouse strains and ind

162 circulating neutrophil numbers, we measured blood neutrophil numbers in p40-deficient (IL12b-/-) mic

163 ated with NF-kappaB activation in peripheral blood neutrophils obtained over the pre-LPS exposure per

164 ic regression analysis showed that increased blood neutrophil (odds ratio, 10.9; P = .002) and sputum

165 nophore-stimulated (A23187; 1-2.5 muM) human blood neutrophils or differentiated HL-60 cells, vitamin

166 an or rat C5a, incubation at pH 7.4 of human blood neutrophils or rat alveolar macrophages (AMs) with

167 Peripheral blood neutrophils (PBNs) from mice with meningitis exhib

168 vities, similar to those of human peripheral blood neutrophils (PBNs) or mouse peripheral blood neutr

169 Blood neutrophils peaked at 6-12 hours, increasing from

170 Blood neutrophils perform an essential host-defense func

171 Blood neutrophils (PMN) are usually unresponsive to CC c

172 Human peripheral blood neutrophils (PMN) plated onto fibrinogen and activ

173 In comparison with peripheral blood neutrophils (PMNs), the decidual neutrophils expre

174 of M. haemolytica LKT with bovine peripheral blood neutrophils (PMNs).

175 We initially constrained the ratio of the blood neutrophil pool to the marrow precursor pool (rati

176 c oxide in exhaled air (r = 0.48, P = .004), blood neutrophils (r = 0.63, P < .001), and bronchial wa

177 nder the curve for LPS-stimulated peripheral blood neutrophils (r = 0.63, p = 0.01).

178 asal G-CSF correlated closely with increased blood neutrophils (r(s) = 0.69, p < 0.005), whereas nasa

179 In addition, the genome-wide response to blood neutrophils (rather than total WBC) was also not w

180 Blood neutrophils recruited to cystic fibrosis (CF) airw

181 We demonstrate that CF blood neutrophils release less secondary and tertiary gr

182 Under the same conditions, C5a binding to blood neutrophils remained intact; in tandem, in vitro c

183 ty, although most plasma cytokine levels and blood neutrophil responses were not key components.

184 et, virtually all major plasma cytokines and blood neutrophil responses were related to marrow-derive

185 Late blood neutrophil responses were related to the presence

186 Consistent patterns of peripheral blood neutrophil responses, as determined by LPS-induced

187 nd phenotypic characterization of peripheral blood neutrophils revealed more mature and responsive ne

188 ecruitment.(1) They report that murine fetal blood neutrophil rolling, adhesion, and extravasation fr

189 Human blood neutrophils rolling on E- or P-selectin reduced th

190 that L-selectin (CD62L) on human peripheral blood neutrophils serves as an E-selectin ligand.

191 After CLP, blood neutrophils showed a reduction in C5aR followed by

192 LP receptor (TSLPR) signaling, had levels of blood neutrophils, spleen myeloid cells, and serum IL-4,

193 Moreover, in vitro exocytosis assays of blood neutrophils suggest that surface nutrient transpor

194 can restore a severely neutropenic patient's blood neutrophil supply and neutrophil inflammation resp

195 Compared with blood neutrophils, TANs displayed an activated phenotype

196 n this process is the polarized migration of blood neutrophils through endothelial cells (ECs) lining

197 table patterns in the response of peripheral blood neutrophils to LPS exist in the human population a

198 Allowing the ratio of blood neutrophils to mitotic neutrophil precursors (R) t

199 process, molecular signals guide circulating blood neutrophils to target specific vessels for extrava

200 monocytoid cells and culturing of peripheral blood neutrophils, treatments which modulate plasminogen

201 in adhesion to Glu-Pg was demonstrable with blood neutrophils, U937 monocytoid cells, and geneticall

202 L-60, the T cell line Jurkat, and peripheral blood neutrophils, undergoing apoptosis induced either w

203 In experimental murine sepsis, pHi of blood neutrophils was analogously alkalinized, which cou

204 rleukin 17A (IL-17) production by peripheral blood neutrophils was examined in patients with fungal k

205 inally, ex vivo adhesion of mouse peripheral blood neutrophils was strongly reduced after oral admini

206 Normal peripheral blood neutrophil were incubated overnight in BALF from n

207 Peripheral blood neutrophils were analyzed for intracellular hydrog

208 Blood neutrophils were cultured for 17 to 20 hours in th

209 Blood neutrophils were isolated from healthy volunteers

210 Peripheral blood neutrophils were isolated from patients with COPD

211 Blood neutrophils were isolated using a standard gradien

212 These higher blood neutrophils were only seen in obese women and not

213 Whole blood neutrophils were pretreated with or without inotro

214 deed, in 18 CF patients with stable disease, blood neutrophils were readily deficient in the pivotal

215 When normal blood neutrophils were stimulated in vitro with LPS and

216 Isolated peripheral blood neutrophils were stimulated with 19 periodontal ba

217 When human peripheral blood neutrophils were stimulated with parasite Ag, they

218 ause of the finding of morulae in peripheral blood neutrophils were studied for determination of the

219 hemokine receptor 2 is expressed on lung and blood neutrophils, which are increased upon E. coli infe

220 e host, can induce an increase in peripheral blood neutrophils, which are predisposed to NET formatio

221 transient expression and release of OSM from blood neutrophils, which was more rapid than the express

222 ecretion of beta-glucuronidase in peripheral blood neutrophils with a potency of approximately 1/1000

223 Incubation of peripheral blood neutrophils with RA synovial fluid led to TNFalpha

224 Incubation of peripheral blood neutrophils with thapsigargin, an inhibitor of the

225 report, we show that treatment of peripheral blood neutrophils with the chemotactic peptide fMLP or w

226 ation, 3 neutrophil subsets are found in the blood: neutrophils with a conventional segmented nucleus

227 9-L) induced a rapid and robust expansion of blood neutrophils, with a concomitant reduction in PBMCs