ライフサイエンスコーパス: blood spot

1 ta9-tetrahydrocannabinol (THC) from a single blood spot.

2 r and the time since deposition (TSD) of the blood spot.

3 the age of the originator and the TSD of the blood spot.

4 s occasionally observed with FFPET and dried blood spot.

5 entrations of tenofovir diphosphate in dried blood spots.

6 currently used PCR methods from filter paper blood spots.

7 enofovir diphosphate concentrations in dried blood spots.

8 correlated with CMV viral load in the dried blood spots.

9 c DNA obtained from Guthrie cards with dried blood spots.

10 riptyline, lidocaine, and sunitinib in dried blood spots.

11 s of HIV infection in infants by using dried blood spots.

12 trophy by the creatine kinase level on dried blood spots.

13 od to detect HIV type 1 (HIV-1) DNA in dried blood spots.

14 rom children with available neonatal Guthrie blood spots.

15 Of the other nine patients, six had positive blood spots.

16 measurement of transferrin receptor in dried blood spots.

17 sma-specific immunoglobulin M (IgM) in dried blood spots.

18 h higher LINE1 methylation levels in newborn blood spots.

19 hors measured EDA in serum, saliva and dried blood spots.

20 roscope) and another one consisting of dried blood spots.

21 sed to spot the blood, or the temperature of blood spotted.

22 rson-years if drug was not detected in dried blood spots, 2.3 infections per 100 person-years if drug

23 L (3.47 pmol/L), total testosterone in dried blood spots (8-10 muL) with a LLOQ of 40 pg/mL, and free

24 l in Kampala, Uganda, and obtained for dried blood spot analysis.

25 ction of expanded CGG alleles using a single blood spot and in principle is suitable for large scale

26 e at room temperature, the punched out dried blood spot and the foam was dissolved in 300 muL of 1 mM

27 y (ELISA) for quantifying insulin from dried blood spots and demonstrate its application in a large t

28 elf to samples such as tumor biopsies, dried blood spots and fluids including urine and CSF to develo

29 DNA was obtained from newborn screening blood spots and genotyped for the allelic variants of TG

30 twin pairs using DNA isolated from neonatal blood spots and identified genes affected by extremely r

31 ples enriched for proviral DNA such as dried blood spots and increased use of next-generation sequenc

32 ith activity data determined from both dried blood spots and serum samples, giving an informative dia

33 cent improvements for accurately using dried blood spots and the imminent appearance to the market of

34 inflammatory marker levels in neonatal dried blood spots and their association with later risk of sch

35 LISA) for quantifying adiponectin from dried blood spots and then demonstrate its application in a la

36 onication) of the paper containing the dried blood spots, and acidification of extraction solvents.

37 red levels of tenofovir diphosphate in dried blood spots; and (3) examine patterns of risk behavior w

38 Cotinine levels in dried blood spots are an accurate biomarker of maternal smokin

39 The archived dried blood spots are an important and precious resource for g

40 Drug concentrations in dried blood spots are strongly correlated with protective bene

41 lical cord blood to assess cotinine in dried blood spots as a biomarker of maternal smoking close to

42 th: (i) C-reactive protein, assayed in whole-blood spots as an indicator of immunostimulation; (ii) s

43 y their performance in reactions using dried blood spots as the enzyme source.

44 Bio-sampling was randomised to blood spot, buccal cell or no request.

45 protein) were analyzed in eluates from dried blood spots by enzyme-linked immunosorbent assay.

46 variants by direct surface sampling of dried blood spots by use of an Advion Triversa Nanomate automa

47 Dried blood spots can be used for comprehensive, untargeted li

48 m ferritin and transferrin receptor in dried blood spots can be used to facilitate the identification

49 tion-mass spectrometry in conjunction with a blood spot cartridge that we can determine the relative

50 rmined by polymerase chain reaction on dried blood spots collected at 6 and 12 weeks of age.

51 cts from human whole blood samples and dried blood spots collected on chromatography paper.

52 -HRMS) in archived DBS samples (in total, 51 blood spot composites from 1224 newborns) collected from

53 A fixed area punch in dried blood spot (DBS) analysis is assumed to contain a fixed

54 omparison of Aptima results for paired dried blood spot (DBS) and plasma specimens archived from part

55 his study were to develop and validate dried blood spot (DBS) assays for the quantification of ambris

56 Since March 2004, we obtained 2135 dried blood spot (DBS) citrulline samples from 57 intestinal t

57 A dried blood spot (DBS) is a well-accepted means for the collec

58 -concept study combining water-soluble dried blood spot (DBS) material in liquid chromatography-tande

59 The dried blood spot (DBS) matrix has significant utility for appl

60 Monitoring by dried blood spot (DBS) provides patients the opportunity to sa

61 ith the bioanalytical methods used for dried blood spot (DBS) sample analysis.

62 ty issues associated with conventional dried blood spot (DBS) sample when a subpunch is taken.

63 )D3] concentrations in stored neonatal dried blood spot (DBS) samples are associated with pediatric f

64 To improve EID services in Ukraine, dried blood spot (DBS) samples obtained from 237 HIV-exposed c

65 Dried blood spot (DBS) samples on filter paper are surging in

66 sing paired reconstituted dried filter paper blood spot (DBS) samples to assess the feasibility of us

67 quantitative bioanalysis of drugs from dried blood spot (DBS) samples, using an MS detector, with or

68 lin can be measured in either serum or dried blood spot (DBS) samples.

69 ul for online cleanup of extracts from dried blood spot (DBS) samples.

70 s an increasing interest in the use of dried blood spot (DBS) sampling and multiple reaction monitori

71 The potential of dried blood spot (DBS) sampling as an alternative for classica

72 Dried blood spot (DBS) sampling is recognized as a valuable al

73 We instituted dried blood spot (DBS) specimen monitoring of citrulline to si

74 Blood samples were collected as dried blood spot (DBS) specimens from all participants for qua

75 gained substantial experience with the dried blood spot (DBS) technique as an alternative.

76 The dried blood spot (DBS) technique can be used to collect, store

77 , and simplified shipping and storage, dried blood spot (DBS) techniques have faced adoption resistan

78 Dried blood spot (DBS) technology is believed to be a viable s

79 Dried blood spot (DBS), dried plasma spot (DPS), and plasma sp

80 umbilical cord (UC) tissue and newborn dried blood spot (DBS)-extracted genomic DNA (gDNA) as an alte

81 Dried blood spots (DBS) are an alternative specimen type for H

82 Since dried blood spots (DBS) are routinely collected for metabolic

83 Dried blood spots (DBS) are simpler to prepare, store, and tra

84 Drug concentrations in hair and dried blood spots (DBS) are used to assess long-term-exposure;

85 Dried blood spots (DBS) are useful for molecular assays but ar

86 nder the development and acceptance of dried blood spots (DBS) as a widely used quantitative bioanaly

87 ral therapy (ART) guidelines recommend dried blood spots (DBS) as an alternative specimen type for vi

88 S assay to determine subtype B DRMs in dried blood spots (DBS) collected from patients on antiretrovi

89 Dried blood spots (DBS) collected onto filter paper have eased

90 The use of dried blood spots (DBS) could ameliorate many problems of vita

91 s (CMV) load in finger-stick-collected dried blood spots (DBS) could potentially be useful for field

92 cytes isolated by magnetic sorting and dried blood spots (DBS) derived from 50 mul of peripheral bloo

93 bust LC-MS/MS-based enzyme assay using dried blood spots (DBS) for the diagnosis of pyridox(am)ine 5'

94 for online extraction and analysis of dried blood spots (DBS) from DBS paper cards to a multidimensi

95 We tested 617 dried blood spots (DBS) from human immunodeficiency virus-expo

96 Dried blood spots (DBS) have been used as alternative specimen

97 HIV Early Infant Diagnosis (EID) from dried blood spots (DBS) in low- to middle-income countries sin

98 ethod for analyzing perchlorate in the dried blood spots (DBS) of newborns.

99 ncentrations in clinical studies using dried blood spots (DBS) on paper, rather than conventional pla

100 examined the stability of HIV-1 DNA in dried blood spots (DBS) stored in humid heat and at -20 degree

101 on (LOD) of the new test in plasma and dried blood spots (DBS) was determined with the 2nd Internatio

102 In total, dried blood spots (DBS) were collected from 276 individuals.

103 HIV genotyping from dried blood spots (DBS) with noncommercial (in-house) assays m

104 inborn errors of metabolism (IEM) from dried blood spots (DBS) with quality assurance.

105 um samples and 40-10,000 pg/mL for the dried blood spots (DBS) with R(2) >0.998.

106 stick placed on filter paper (known as dried blood spots (DBS)) is more advantageous.

107 re IFX in 100-fold diluted extracts of dried blood spots (DBS), and LOD achieved was below 2 ng/mL.

108 for early infant diagnosis of HIV from dried blood spots (DBS), viral load monitoring with this syste

109 tion of methotrexate polyglutamates in dried blood spots (DBS).

110 e the analysis of therapeutic drugs in dried blood spots (DBS).

111 d yield of DNA extracted from neonatal dried blood spots (DBS).

112 ould facilitate more widespread use of dried blood spots (DBS).

113 0), cerebrospinal fluid (CSF; n = 36), dried blood spots (DBS; n = 104), and dried plasma spots (DPS;

114 eloped and applied a broadly sensitive dried-blood-spot (DBS)-based genotyping assay for surveillance

115 s of targeted drugs and metabolites in dried blood spots (DBSs) and whole mouse thin tissue sections

116 s spectrometry (tandem-MS) analysis of dried blood spots (DBSs) collected at birth can identify newbo

117 n identify metabolite abnormalities in dried blood spots (DBSs) from affected patients, with the fina

118 ervational cohort study using data and dried blood spots (DBSs) from the Breastfeeding, Antiretrovira

119 Dried blood spots (DBSs) have had a long history in disease sc

120 e in resource-limited settings, use of dried blood spots (DBSs) is being adopted.

121 Ten dried blood spots (DBSs) were assembled that contained P. falc

122 Dried blood spots (DBSs), collected for the newborn screening

123 Blood spot DNA from this subject displayed chimerism in

124 Whole genome amplification of dried blood spot DNA has been used to provide DNA for genome-w

125 A set of 384 SNPs were genotyped in blood spot DNA samples from 447 P. falciparum infected s

126 tion method to amplify parasite genomes from blood spot DNA samples.

127 more robust than genotyping amplified dried blood spot DNA, is comparable in cost, and can be done w

128 re robust, high-accuracy genotyping of dried blood spot DNA.

129 f the coating was then used for an extracted blood spot (EBS) sampling approach, a new sampling metho

130 erythronate in stable isotope-assisted dried blood spot experiments.

131 quires a simple extraction step from a dried blood spot followed by the quantification of product by

132 is used genomic DNA extracted from the dried blood spot followed by whole genome amplification with a

133 ning by creatine kinase (CK) levels in dried blood spots followed by mutation detection in those with

134 However, homogenization of the dried blood spots, followed by a 24 h exposure to solvents, an

135 ces provided anonymous survey data and dried blood spots for HIV serostatus assessment.

136 ences, and 1,220 (70.2%) also provided dried blood spots for HIV testing.

137 ) based assays of lysosomal enzymes in dried blood spots for the early detection of Pompe, Fabry, and

138 sed elevated creatine kinase levels in dried blood spots for the initial screening, with the diagnosi

139 for the Determine and Vikia tests and dried blood spots for the reference standard test (AxSYM HBsAg

140 tested for malarial parasitemia using dried blood spots from 12, 24, and 36 weeks of age.

141 Paediatricians collected a median of 8 blood spots from 13,487 (97%) children.

142 plication) in which paediatricians collected blood spots from 13,879 children aged 11.5 years from 31

143 , prediagnosis samples in 4 of 16), neonatal blood spots from 21 DS children without clinically evide

144 We examined neonatal blood spots from 214 children with ASD (141 severe, 73 m

145 tic Disease Screening Program provided dried blood spots from 428 newborns delivered in 2001-2003 wit

146 hen compared with microscopy using 891 dried blood spots from a cohort of 77 Ugandan children followe

147 EL-AML1 genomic fusion sequences in neonatal blood spots from each child.

148 1) and tripeptidyl peptidase (TPP1) in dried blood spots from newborns using tandem mass spectrometry

149 We collected blood spots from patients with microscopy or rapid test

150 ally identified TEL-AML1 fusion sequences in blood spots from the identical twins, diagnosed with con

151 easuring immunoreactive trypsinogen on dried blood spots (from April 1985 through June 1991) or by co

152 exity are high, DNA was extracted from dried blood spots, genes of interest were amplified, amplicons

153 found that measurements of cotinine in dried blood spots had high sensitivity (92.3%) and specificity

154 The use of dried blood spots has increased in research and clinical setti

155 e acyl-specific lipidomic profiling of dried blood spots has yet to be examined.

156 and transportation of samples, such as dried blood spots, has improved test accessibility, the result

157 Studies in monozygotic twins and archived blood spots have provided compelling evidence of a singl

158 sm, this patient had a persistently elevated blood spot hydroxybutyrylcarnitine concentration when fe

159 sequencing of FFPET, whole blood, and dried blood spot in the evaluation of inherited CV disorders.

160 ly quantified fasting adiponectin from dried blood spots in 13,329 of 13,879 (96%) children.

161 Paediatricians collected dried blood spots in a follow-up of 13,879 fasted children age

162 ne kinase (CK) levels are increased on dried blood spots in newborns related to the birthing process.

163 ucocerebrosidase enzymatic activity in dried blood spots in patients with Parkinson's disease (n = 51

164 ured drug concentrations in plasma and dried blood spots in seroconverters and a random sample of ser

165 19%-47%) by increasing DNA input from dried blood spots into polymerase chain reaction.

166 ic material, including cheek swabs and dried blood spots, is described briefly.

167 n real time (DART)-MS/MS, where, for a 5 muL blood spot, LOQs of 0.2 and 1 mug/mL, respectively, were

168 ood specimens from newborns, stored as dried blood spots, may provide a low-cost method to objectivel

169 us levels were assessed by a validated dried blood spot method for sampling and measurement.

170 d by the patients themselves using the dried blood spot method.

171 d by the patients themselves using the dried blood spot method.

172 men type (FFPET versus whole blood and dried blood spot; n=12).

173 l receptor excision circles (TRECs) in dried blood spots obtained at birth permits population-based n

174 The authors analyzed archival dried blood spots obtained from newborns to assess whether lev

175 mately 3 microL of blood) punched from dried blood spots obtained from: i) whole blood standards (val

176 1 methylation in DNA isolated from the dried blood spots of 36,124 deidentified newborn males.

177 rs of T and B cell numbers in neonatal dried blood spots of 99 children with cCMV and 54 children wit

178 c gene fusion sequences in archived neonatal blood spots of individuals who subsequently developed le

179 kemia and retrospective scrutiny of neonatal blood spots of patients with leukemia indicate that chro

180 ave been developed for the analysis in dried blood spots of steroids and lysosomal enzymes.

181 r detection of malaria parasites using dried blood spots offers a sensitive and efficient approach fo

182 Sample preparation of blood spots on commercial cards was also performed (What

183 blood films for microscopic examination and blood spots on filter paper.

184 ative analysis of enzyme activities in dried blood spots on newborn screening cards has emerged as a

185 We used dried blood spots once every 6 months provided by participants

186 lonotypic E2A-PBX1 translocation in neonatal blood spots, or Guthrie cards, obtained from the childre

187 hod allows for repeated analysis of a single blood spot over a prolonged time period and is tolerant

188 ts own cutoff of interpret results for dried blood spots prepared from either adults with serology su

189 Measurements on serum and blood spots prepared from venous blood were performed in

190 ne, phenylalanine, and methionine on a dried blood spot requiring a 2 min run.

191 We obtained punch samples from dried blood spots routinely collected from HIV-exposed infants

192 he first to sequence BPD exomes from newborn blood spot samples and identify with high confidence gen

193 l load in many countries is to collect dried blood spot samples for testing in regional laboratories;

194 Dried blood spot samples from mothers and their offspring atte

195 Using dried blood spot samples from patients with suspected malaria

196 DNA was extracted from the neonatal dried blood spot samples obtained from the Danish Neonatal Scr

197 R techniques that amplify HIV-1 gag DNA from blood spot samples on filter paper and from correspondin

198 targeted profiles can be obtained from dried blood spot samples that are comparable with whole blood

199 Dried blood spot samples were collected from HIV-exposed child

200 April 5, 2007, and Oct 1, 2014, 16 046 dried blood spot samples were sent from 8859 children in 364 h

201 iquid extraction surface analysis from dried blood spot samples, where hemoglobin is highly abundant.

202 been reported for tissue sections and dried blood spot samples.

203 ns using 30,547 deidentified anonymous dried blood spot samples.

204 m DNA methylation of neonatal cord blood and blood spot samples.

205 troduced to address the limitations of dried blood spot sampling.

206 indicates that current approaches to newborn blood spot screening (NBS) education are ineffective.

207 first recognised, the performance of newborn blood spot screening (NBS) has been continually assessed

208 will facilitate the quality control of dried blood spot sequencing.

209 ty of our method for drug screening on dried blood spots showing excellent linearity (R(2) of 0.998)

210 is of IdS-S by IdS found within a 3 mm dried blood spot specifically produces a nonsulfated product (

211 tes the correlation between plasma and dried blood spot specimen citrulline concentrations after inte

212 Serum and dried blood spot specimens collected for yaws surveillance pro

213 col to assess resistance using remnant dried blood spot specimens from a representative sample of chi

214 FPET (heart) and blood (whole blood or dried blood spot) specimens underwent targeted next-generation

215 r a prolonged time period and is tolerant of blood spot storage conditions.

216 Diet and dried blood spot TC and omega-3 (n-3) index were determined at

217 ood specimens were collected using the dried blood spot technique from 9629 residents (87.6%), and sa

218 le volume restrictions associated with dried-blood-spot technology.

219 Median age at first dried blood spot test was 2.1 (IQR 1.8-2.5) months.

220 67%) individuals with a first negative dried blood spot test, 14 223 (80%) had subsequent dried blood

221 eated infants in Malawi by analysis of dried blood spots tested by nucleic acid silica-bound amplific

222 adherence, assessed by drug levels in dried blood spots tested monthly for the first 3 months.

223 Early infant diagnosis with dried blood spot testing had high uptake in primary care setti

224 Early infant diagnosis with dried blood spot testing was provided by the National AIDS Pro

225 deficiency-which can be diagnosed using dry blood spot testing-is often misdiagnosed as non-alcoholi

226 8 DNA methylation levels measured in newborn blood spot tests, and carotid intima-media thickness (CI

227 spot test, 14 223 (80%) had subsequent dried blood spot tests, of whom 503 seroconverted after follow

228 omole quantities of enzymatic products per a blood spot that are quantified by tandem mass spectromet

229 ure to extract DNA from a portion of a dried blood spot that provides sufficient unamplified genomic

230 d-smear microscopy and PCR analysis of dried blood spots that had been collected every 2 weeks for 7

231 Dried blood spots that had been stored ambiently for 3 to 6 ye

232 Blood spots that were classified as negative were uninfo

233 and in DBS samples; effect of the volume of blood spotted, the device used to spot the blood, or the

234 the input sample volume is much smaller in a blood spot, there is a risk of false negatives with DBS.

235 we introduce a 2-tier system using the dried blood spot to first assess CK with follow-up DMD gene te

236 rin receptor measurements on dried capillary blood spots to identify iron deficiency (ID) in public h

237 and uses predetermined levels of CK on dried blood spots to predict DMD gene mutations.

238 The use of dried blood spots to stabilise and ship samples from clinics t

239 is article compares cotinine levels in dried blood spots to those in umbilical cord blood to assess c

240 markers were measured in eluates from dried blood spots using a bead-based multiplex assay.

241 RNA viral load measurements taken from dried blood spots using a reference panel and field-collected

242 R assay with DNA isolated from routine dried blood spots was developed.

243 ucocerebrosidase enzymatic activity in dried blood spots was measured by a mass spectrometry-based as

244 Cotinine in dried blood spots was measured in 6.35--mm punches by using li

245 The most sensitive parameter in dried blood spots was the ratio of receptor/ferritin, which wa

246 ebruary, 2014, and March, 2015, 99,243 dried blood spots were analysed and results were available for

247 Blood spots were collected at each observation and assay

248 bs were tested for chlamydial infection, and blood spots were collected on filter paper to test for a

249 globin density was measured and filter paper blood spots were collected to determine age-specific ser

250 Dried blood spots were extracted using a methanolic solution o

251 Repeated measures of cotinine in dried blood spots were highly correlated (R(2) = 0.99, P < 0.0

252 ssion revealed that cotinine levels in dried blood spots were slightly lower than those in umbilical

253 enofovir diphosphate concentrations in dried blood spots were stable and high.

254 nk was used to chromatographically elute the blood spot with 0.9% NaCl buffer for 10 min by capillary

255 ted (R(2) = 0.99, P < 0.001) among 100 dried blood spots with cotinine quantitated in 2 separate punc