ライフサイエンスコーパス: bolus dose

1 lar to replicating infections, rather than a bolus dose.

2 r-bearing mice either s.c. or i.p. in single bolus doses.

3 s diltiazem was administered as a slow 10-mg bolus dose (0.1-0.2 mg/kg ideal body weight), and then a

4 urations of NMB effect following a 0.4 mg/kg bolus dose (100% block) of 25a, 27c, and 24a were 16.9,

5 combined immunodeficient (SCID) mice after a bolus dose (18,500 kBq [500 microCi]), using variations

6 then received the (90)Y peptide as a single bolus dose 19 h later, or the therapy cycle was fraction

7 6,203 exposure/follow-up pairs, 13% involved bolus dosing, 49% involved maintenance dosing, and 38% d

8 A cyclosporin A bolus dose (5 mg/kg over 3 hours) was followed by intrav

9 Single bolus dose and 28-days of repeated administration of DMA

10 odynamic, neurohormonal and renal effects of bolus dose and 6-h infusion administration of nesiritide

11 vated in a dose dependent manner following a bolus dose and continuous intravenous infusion.

12 We also observed an association between bolus dosing and infection-related mortality.

13 Cyclosporine in bolus doses appears to increase skin cancer development,

14 04 nmol/h) following either a 40- or 20-nmol bolus dose at 8 h.

15 ng (a) urinary Se excretion as a function of bolus dose; (b) tissue Se accumulation profile; (c) anti

16 osporine after a period of UV exposures, and bolus dosing cyclosporine by gavage and repeated UV expo

17 SNPeCPR consists of large intravenous SNP bolus doses during CPR enhanced by active compression-de

18 Platinum schedules other than bolus dosing every 3 to 4 weeks are effective and may be

19 Bolus doses followed by continuous infusions of cisatrac

20 Midazolam infusion preceded by a high bolus dose in newborn piglets alters systemic and sagitt

21 g intravascular bolus followed by 10% of the bolus dose infused hourly for 24 h) administered 1 h bef

22 le, a formula is provided for predicting the bolus dose necessary to accomplish tumor saturation as a

23 d rats (n = 10) received an intravenous (iv) bolus dose of 0.42 mg/kg of methamphetamine at eight hou

24 ter drug administration, a second respective bolus dose of 0.8 units/kg vasopressin, 200 microg/kg ep

25 or accelerated tissue plasminogen activator (bolus dose of 15 mg and an infusion of 0.75 mg/kg for 30

26 n, and 3 divided doses of 6.3 MBq/mouse or a bolus dose of 18.9 MBq/mouse induced only transient lymp

27 when administered intravenously as a single bolus dose of 3 mg/kg following permanent occlusion of t

28 which adults rats were i.v. injected with a bolus dose of 4 mg/kg doxorubicin, confirmed in vitro fi

29 received regadenoson as a rapid intravenous bolus dose of 400 microg (n = 18) or 500 microg (n = 18)

30 for 3 days, with a single intravenous (i.v.) bolus dose of 5-FU 10 mg/m2 on day 2.

31 kg/m(2)) received an identical, intravenous bolus dose of [1-(14)C]oleate followed by timed subcutan

32 fed state, subjects received orally a single bolus dose of [1-13C]leucine.

33 and their wild type counterparts were fed a bolus dose of [3H]cholesterol and a trace amount of [bet

34 d from six healthy adults treated with a 4-g bolus dose of acetaminophen (APAP) and from three receiv

35 exhibited decreases in RBF in response to a bolus dose of Ang II, further studies evaluated the effe

36 A single bolus dose of compound 15, administered intravenously fo

37 followed 24 h later with a fixed intravenous bolus dose of doxorubicin (60 mg/m2).

38 a, and tachycardia shortly after the initial bolus dose of drug, but serious drug-related adverse eve

39 A bolus dose of E(2)17G (2 micromol) alone decreased the b

40 of standard cardiopulmonary resuscitation, a bolus dose of either 200 microg/kg epinephrine (n = 6) o

41 er 10 to 20 minutes, followed by a 500 mg/m2 bolus dose of FU on days 1, 8, and 15 every 28 days.

42 blood pressure (-3.5 mm Hg), and mean daily bolus dose of insulin (-2.8 units per day) (P</=0.002 fo

43 ght, systolic blood pressure, and mean daily bolus dose of insulin.

44 A single bolus dose of intravenous erythromycin facilitates activ

45 2 microg atRA/g diet) and given a daily oral bolus dose of retinol starting at embryonic day 0.5, 8.2

46 At 133 +/- 2 days a 2.5 microg bolus dose of synthetic ACTH (Synacthen; Ciba Pharmaceut

47 milar to that observed following a 0.2 mg/kg bolus dose of this compound and indicates a lack of cumm

48 One group (n = 8) was treated with LSF (bolus doses of 15 mg/kg at 45 and 89 min plus infusion a

49 Bolus doses of 5, 10 and 10 microg/kg and continuous inf

50 ing in 203 patients with a previous MI using bolus doses of a perfluorocarbon-filled contrast agent (

51 ncristine, and doxorubicin for 96 hours with bolus doses of cyclophosphamide and oral prednisone (EPO

52 Guidelines emphasizing escalating bolus doses of diazepam, and barbiturates if necessary,

53 uling of DZR before using it clinically with bolus doses of DOX above those currently recommended.

54 tect against cardiomyopathy in animals given bolus doses of DOX at varying dose levels.

55 irinotecan, fluorouracil and leucovorin with bolus doses of fluorouracil and leucovorin as first-line

56 operidol titration: all patients received IV bolus doses of haloperidol until agitation was controlle

57 Intravenous bolus doses of insulin were administrated to the rabbits

58 mpathetic nerve activity (SNA) to increasing bolus doses of intravenous 5-HT (1, 2.5, 5, 10, 25 mu g/

59 (P<0.001) and requested additional epidural bolus doses of local anesthetic (P=0.01).

60 INTERPRETATIONS: Quarterly bolus doses of oral vitamin D(3) supplementation to infa

61 ular function was stimulated with increasing bolus doses of phenylephrine (PE) following maternal veh

62 g baroreflex logistic function curves, using bolus doses of phenylephrine and sodium nitroprusside, i

63 etically mediated pressor responses, because bolus doses of phenylephrine evoked attenuated pressor r

64 cardiac chronotropic responses to exogenous bolus doses of phenylephrine, angiotensin II and arginin

65 hours before transplantation, under covering bolus doses of prednisone to prevent cytokine reactions.

66 and raising blood pressure with intravenous bolus doses of sodium nitroprusside and phenylephrine.

67 rginine (L-NMMA) (3 mg kg(-1)) or increasing bolus doses of the nitric oxide donor, sodium nitropruss

68 Bolus dosing of fentanyl and midazolam fails to reduce t

69 l of continuous infusion versus intermittent bolus dosing of piperacillin-tazobactam, meropenem, and

70 r the fibrin component, front-loading and/or bolus dosing of plasminogen activators (PAs) has identif

71 Thus, repeat bolus dosing of surfactant or bolus treatment followed b

72 on with either daily (metronomic) or weekly (bolus) doses of AT101.

73 to basiliximab therapy received a 20 mg i.v. bolus dose on days 0 and 4, and the majority of patients

74 cant response for vitamin D3 when given as a bolus dose (P = 0.0002) compared with administration of

75 entation may result in fewer infections than bolus dosing, particularly among patients with a cathete

76 eatment for severe sepsis, with intermittent bolus dosing standard therapy, despite a strong theoreti

77 up to two identical tecadenoson intravenous bolus doses were administered.

78 Intravenous bolus dose, when given, and diltiazem infusion rate and

79 modialysis patients to compare the safety of bolus dosing, which provides a large amount of iron over

80 Patients in the stepwise group received one bolus dose with the largest meal, with additional insuli