ライフサイエンスコーパス: bone morphogenetic protein

1 bsence of the type I collagen C-propeptidase bone morphogenetic protein 1 (BMP1) causes type XII oste

2 Mutations in bone morphogenetic protein 1 (BMP1) in humans or deletio

3 es the cleavage of C-terminal procollagen by bone morphogenetic protein 1 (BMP1).

4 The four members of the family: bone morphogenetic protein-1 (BMP-1), mammalian tolloid

5 lial growth factor A (VEGFA), interleukin-2, bone morphogenetic protein-10, VEGFC, and 2 (FGF2) were

6 Growth differentiation factor 9 (GDF9) and bone morphogenetic protein 15 (BMP15) are secreted durin

7 io of growth differentiation factor 9 (GDF9):bone morphogenetic protein 15 (BMP15) at diestrus.

8 terms of osteoblastic differentiation using bone morphogenetic protein 2 (BMP-2) added to the medium

9 d a positive effect of tissue-derived BGN on bone morphogenetic protein 2 (BMP-2) function, which is

10 Parbendazole up-regulates bone morphogenetic protein 2 (BMP-2) gene expression and

11 Although bone morphogenetic protein 2 (BMP-2) is known to stimula

12 The expressions of bone morphogenetic protein 2 (BMP2) and BMP6; sex-determ

13 study, we discovered the double deletion of bone morphogenetic protein 2 (Bmp2) and bone morphogenet

14 ation of an injectable and porous nCS/A with bone morphogenetic protein 2 (BMP2) gene-modified MSCs a

15 Bone morphogenetic protein 2 (BMP2) in chromosomal regio

16 Bone morphogenetic protein 2 (BMP2) promotes PF formatio

17 n of smooth muscle contractions by secreting bone morphogenetic protein 2 (BMP2), which activates BMP

18 Recombinant human bone morphogenetic protein 2 (rhBMP-2) has been used for

19 ptide nanostructures amplified signalling of bone morphogenetic protein 2 significantly more than the

20 phogen action during animal development, the bone morphogenetic protein 2/4 (BMP2/4)-like ligand Deca

21 st differentiation promoted and sustained by bone morphogenetic protein-2 (BMP-2) and TGF-beta, respe

22 rently, sustained in vivo delivery of active bone morphogenetic protein-2 (BMP-2) protein to responsi

23 ch as fibroblast growth factor-2 (FGF-2) and bone morphogenetic protein-2 (BMP-2) work synergisticall

24 ECFCs produced bone morphogenetic protein-2 (BMP-2), a potent osteoindu

25 gulates differentiation of OCs downstream of bone morphogenetic protein-2 (BMP-2)-stimulated osteobla

26 l with a collagen scaffold soaked in saline, bone morphogenetic protein-2 (BMP-2; 200 ng), 1 muM CGS2

27 al and temporal release of recombinant human bone morphogenetic protein-2 (BMP2) and vascular endothe

28 Although bone morphogenetic protein-2 (BMP2) has demonstrated ext

29 on of mesenchymal stem cells (MSCs), whereas bone morphogenetic protein-2 (BMP2) promotes osteogenic

30 ayer coating carrying as little as 200 ng of bone morphogenetic protein-2 and platelet-derived growth

31 In osteoblasts, CypA is necessary for BMP-2 (Bone Morphogenetic Protein-2)-induced Smad phosphorylati

32 In the present study, bone morphogenetic protein-2/BMP-2-directed osteogenic d

33 infection and transcript analysis identified bone morphogenetic protein 4 (BMP4) as a candidate endot

34 Bone morphogenetic protein 4 (BMP4) has potential as an

35 n of bone morphogenetic protein 2 (Bmp2) and bone morphogenetic protein 4 (Bmp4) in the dental epithe

36 response to transient (24-36 h) exposure to bone morphogenetic protein 4 (BMP4) plus inhibitors of A

37 coprotein 1 (GLG1) expression and downstream bone morphogenetic protein 4 (BMP4) signaling and also r

38 es different concentrations of activin A and bone morphogenetic protein 4 (BMP4) to polarize cells in

39 TGF-beta signaling mediated by pSMAD2, bone morphogenetic protein 4 (BMP4), EGF, or PDGF was un

40 Consequently, bone morphogenetic protein 4 (BMP4), or ectopic expressi

41 own to promote beta-cell function, including bone morphogenetic protein 4 (BMP4).

42 e been identified, including sonic hedgehog, bone morphogenetic protein 4 and multiple members of the

43 Contributions of bone morphogenetic protein 4 and transforming growth fac

44 le protocol, using defined medium containing bone morphogenetic protein 4 by which human pluripotent

45 Bone morphogenetic protein 4 up-regulated alphaB-crystal

46 e framework whereby activation of TGF-beta2, bone morphogenetic protein 4, Wnt/beta-catenin, or immun

47 Bone morphogenetic proteins 4 and 7 (BMP4 and BMP7) are

48 Bone morphogenetic protein-4 (BMP4) plays a key role in

49 es for hESC differentiated to TB by means of bone morphogenetic protein-4 and inhibitors of activin A

50 nd subsequent transcriptional suppression of bone morphogenetic proteins 5 and 7.

51 Bone morphogenetic protein 6 (BMP6) contributes to the i

52 Lack of either bone morphogenetic protein 6 (BMP6) or the BMP corecepto

53 Bone morphogenetic protein 6 (BMP6) signaling in hepatoc

54 gion containing an excellent candidate gene, Bone morphogenetic protein 6 (Bmp6).

55 ether these molecules intersect in vivo with bone morphogenetic protein 6 (BMP6)/mothers against deca

56 ivary gland fluid secretion, is regulated by bone morphogenetic protein 6.

57 fragment was identified to bind to the human bone morphogenetic protein-6 (hBMP6) growth factor and c

58 ansforming growth factor beta (TGFbeta), and bone morphogenetic protein 7 (BMP7), CD1c(+) dendritic c

59 We further identify bone morphogenetic protein 7 as one of them.

60 VEGF-A, VEGF-C, VEGF-D, VEGF-A isoform 121, bone morphogenetic protein 7, macrophage colony-stimulat

61 sue into endocrine cell types by exposure to bone morphogenetic protein 7.

62 (drMM) in the presence of human recombinant bone morphogenetic protein 7/human recombinant fibroblas

63 rogeneous, congenital heart diseases, and to bone morphogenetic proteins 7 as an effective treatment

64 hat supplementation of exogenous recombinant bone morphogenetic proteins 7 effectively ameliorates en

65 echanisms involved revealed the induction of bone morphogenetic protein-7 (BMP7) expression, a critic

66 Bone morphogenetic protein-7 (BMP7) is an antifibrotic c

67 We evaluated the effects of THR-184, a bone morphogenetic protein-7 agonist, in patients at hig

68 cluding fibroblast growth factor 21 (FGF21), bone morphogenetic protein 8b (BMP8b), growth differenti

69 Two members of the TGFbeta family, bone morphogenetic protein 9 (BMP9) and BMP10, have been

70 T is caused by loss-of-function mutations in bone morphogenetic protein 9 (BMP9)-ALK1-Smad1/5/8 signa

71 r-like kinase 1 (ALK1), endoglin, Smad4, and bone morphogenetic protein 9 (BMP9).

72 Bone morphogenetic proteins 9 and 10 (BMP9/BMP10) are ci

73 Our objective is to determine circulating Bone morphogenetic protein-9(BMP-9) levels in subjects w

74 T signaling did not significantly affect the bone morphogenetic protein activity.

75 Bone morphogenetic protein and activin membrane-bound in

76 in vitro, and we identified ligands for the bone morphogenetic protein and insulin pathways as proad

77 otein negatively regulates the activities of bone morphogenetic protein and phosphoinositide 3-kinase

78 To address whether elevated activities of bone morphogenetic protein and PI3K/AKT signaling pathwa

79 valves demonstrated activation of canonical bone morphogenetic protein and Wnt/beta-catenin signalin

80 lls (hESCs) have been routinely treated with bone morphogenetic protein and/or inhibitors of activin/

81 ntiation and new bone formation through WNT, bone morphogenetic protein, and Notch signaling pathways

82 ation of Hedgehog, fibroblast growth factor, bone morphogenetic protein, and Wnt signaling in the gen

83 , Indian hedgehog, fibroblast growth factor, bone morphogenetic protein, and Wnt signaling pathways i

84 cardiogenic fate of CNC(kit) is regulated by bone morphogenetic protein antagonism, a signaling pathw

85 expression of the gene encoding mesenchymal bone morphogenetic protein antagonist, GREM1.

86 Our aim was to delineate the role of bone morphogenetic protein (BMP) 2 signaling in lymphati

87 l ectoderm (PPE) that requires inhibition of bone morphogenetic protein (BMP) and expresses the key r

88 Here, we show how Bone Morphogenetic Protein (BMP) and Fibroblast Growth F

89 Here, we show that opposing gradients of bone morphogenetic protein (BMP) and Nodal, two transfor

90 y 2 signaling pathways: the "iron-regulated" bone morphogenetic protein (BMP) and the inflammatory JA

91 We found that modulation of bone morphogenetic protein (BMP) and WNT signaling combi

92 t in the context of reduced ShcA levels, the bone morphogenetic protein (BMP) antagonist chordin-like

93 We demonstrate here that expression of the bone morphogenetic protein (BMP) antagonist gremlin 1 de

94 We have recently shown that the bone morphogenetic protein (BMP) antagonist Gremlin 2 (G

95 This is due to induction of the bone morphogenetic protein (BMP) antagonist Gremlin-1, a

96 GREMLIN 2 (GREM2) is a strong bone morphogenetic protein (BMP) antagonist that is know

97 expression of chordin (chd), which encodes a bone morphogenetic protein (BMP) antagonist that is loca

98 cted gene aberrant in neuroblastoma (DAN), a bone morphogenetic protein (BMP) antagonist we detected

99 e that CHRDL1 encodes Ventroptin, a secreted bone morphogenetic protein (BMP) antagonist, the molecul

100 We further identified bone morphogenetic protein (BMP) as a candidate myocardi

101 Hemojuvelin is a bone morphogenetic protein (BMP) co-receptor.

102 The bone morphogenetic protein (Bmp) family of secreted mole

103 The Bone Morphogenetic Protein (BMP) family reiteratively si

104 Distinct pools of the bone morphogenetic protein (BMP) Glass bottom boat (Gbb)

105 iron homeostasis by direct interaction with bone morphogenetic protein (BMP) ligands to induce hepci

106 that injury stimulates the production of two bone morphogenetic protein (BMP) ligands, Dpp and Gbb, w

107 Smad transcription factors critical for the bone morphogenetic protein (BMP) pathway and the DNA rep

108 Mutations in the Bone Morphogenetic Protein (BMP) pathway are associated

109 equencing (ChIP-seq) data, we identified the bone morphogenetic protein (BMP) pathway as a potential

110 Here we demonstrate that the bone morphogenetic protein (BMP) pathway can also be reg

111 ion and specific decreased expression of the bone morphogenetic protein (BMP) pathway component Mad.

112 Fine-tuning of the bone morphogenetic protein (BMP) pathway is essential fo

113 At diagnosis, deregulation of the bone morphogenetic protein (BMP) pathway is involved in

114 in particular the dual modulation of Wnt and bone morphogenetic protein (BMP) pathway signaling, this

115 on the transforming growth factor (TGF)-beta/bone morphogenetic protein (BMP) pathway, which is one o

116 ess of endodermal development, including the Bone morphogenetic protein (Bmp) pathway.

117 ransforming growth factor beta (TGFbeta) and bone morphogenetic protein (BMP) pathways.

118 Beta-catenin/Tcf and the TGF-beta bone morphogenetic protein (BMP) provide critical molecu

119 The bone morphogenetic protein (BMP) receptor Tkv localizes

120 14-17 of CRIM1 (cysteine-rich transmembrane bone morphogenetic protein (BMP) regulator 1).

121 ly in mice, which specify germ cells through bone morphogenetic protein (BMP) signal-mediated inducti

122 red neogenic hair follicles, which triggered bone morphogenetic protein (BMP) signaling and then acti

123 ects of Matn3 on chondrocyte hypertrophy and bone morphogenetic protein (Bmp) signaling by quantifyin

124 We showed previously that SMOC inhibits bone morphogenetic protein (BMP) signaling downstream of

125 Loss of the growth-suppressive effects of bone morphogenetic protein (BMP) signaling has been demo

126 Bone Morphogenetic Protein (BMP) signaling has been impl

127 To investigate the role of bone morphogenetic protein (BMP) signaling in osteoclast

128 hem, a source of Wingless-related (WNT) and bone morphogenetic protein (BMP) signaling in the dorsom

129 result of differential regulation of Wnt and bone morphogenetic protein (BMP) signaling in these two

130 has been constructed and, here, we show that bone morphogenetic protein (BMP) signaling is essential

131 We have investigated whether bone morphogenetic protein (BMP) signaling is involved i

132 Here we show that hippocampal bone morphogenetic protein (BMP) signaling is modulated

133 While it has been demonstrated that bone morphogenetic protein (Bmp) signaling is required f

134 The bone morphogenetic protein (BMP) signaling pathway compr

135 ibit Ras signaling and may also activate the bone morphogenetic protein (BMP) signaling pathway in co

136 IL-1beta activated the bone morphogenetic protein (BMP) signaling pathway in he

137 coagulation factor fibrinogen activates the bone morphogenetic protein (BMP) signaling pathway in ol

138 We previously reported that the bone morphogenetic protein (BMP) signaling pathway is cr

139 The bone morphogenetic protein (BMP) signaling pathway is es

140 In the adult Drosophila midgut the bone morphogenetic protein (BMP) signaling pathway is re

141 The bone morphogenetic protein (BMP) signaling pathway regul

142 Hepcidin expression is induced via the bone morphogenetic protein (BMP) signaling pathway that

143 rates that RNAi silencing of a member of the Bone Morphogenetic Protein (BMP) signaling pathway, Deca

144 er, SMAD4 is also a central component of the bone morphogenetic protein (BMP) signaling pathway, impl

145 f these mutants target the components of the Bone Morphogenetic Protein (BMP) signaling pathway, reve

146 The bone morphogenetic protein (BMP) signaling pathways have

147 ls (DCDMLs), we investigated how the FGF and bone morphogenetic protein (BMP) signaling pathways posi

148 axis is established and patterned by Wnt and bone morphogenetic protein (BMP) signaling pathways, res

149 A morphogen gradient of Bone Morphogenetic Protein (BMP) signaling patterns the

150 Bone morphogenetic protein (BMP) signaling plays a key r

151 between transforming growth factor beta1 and bone morphogenetic protein (BMP) signaling plays an impo

152 Bone morphogenetic protein (BMP) signaling plays many ro

153 Inhibition of bone morphogenetic protein (BMP) signaling prevents the

154 The family of TGF-beta and bone morphogenetic protein (BMP) signaling proteins has

155 Bone morphogenetic protein (BMP) signaling regulates ear

156 Bone morphogenetic protein (BMP) signaling was activated

157 Although antagonists of bone morphogenetic protein (BMP) signaling, such as Nogg

158 elf-renewing SCs, Foxc1 activates Nfatc1 and bone morphogenetic protein (BMP) signaling, two key mech

159 per, notable for roles in Wingless (Wnt) and bone morphogenetic protein (BMP) signaling, were differe

160 al in the Drosophila ovary where it enhances bone morphogenetic protein (BMP) signaling.

161 TGF-beta and activin signals while enhancing bone morphogenetic protein (BMP) signaling.

162 cell (SC), grows selectively in response to bone morphogenetic protein (BMP) signaling.

163 and VEGF-A, which is indicative of increased bone morphogenetic protein (BMP) signaling.

164 ontrolling iron homeostasis, is regulated by bone morphogenetic protein (BMP) signaling.

165 molecule (RGM)-mediated axon guidance and in bone morphogenetic protein (BMP) signaling.

166 wingless-related integration site (WNT), and bone morphogenetic protein (BMP) signalling interactions

167 reveals that complementary components of the bone morphogenetic protein (BMP) signalling pathway are

168 s myocardial trabeculation through Erbb2 and bone morphogenetic protein (BMP) signalling, we discover

169 pression and signaling are up-regulated, and bone morphogenetic protein (BMP) signals are impaired.

170 rfamily of signaling pathways, including the bone morphogenetic protein (BMP) subfamily of ligands an

171 c mathematical model of tissue genesis using bone morphogenetic protein (BMP) to represent of a class

172 and Wnt/beta-catenin) or share (TGFbeta and bone morphogenetic protein (BMP)) core signaling compone

173 This data shows that Wnt, bone morphogenetic protein (BMP), and fibroblast growth

174 ys, epidermal growth factor receptor (EGFR), bone morphogenetic protein (BMP), Jun kinase (JNK), JAK/

175 dels commonly increase signaling of the Wnt, bone morphogenetic protein (BMP), or Ras/ERK pathways, c

176 FE) is specified by sequential inhibition of bone morphogenetic protein (BMP), transforming growth fa

177 ial cells (recell-dTBs); 3) dTBs seeded with bone morphogenetic protein (BMP)-2 (dTB-BMPs); and 4) fr

178 Bone morphogenetic protein (BMP)-2 is used clinically fo

179 owth factor (TGF)-beta family, TGF-beta1 and bone morphogenetic protein (BMP)-2, in synovial fibrobla

180 Hyperactivation of the bone morphogenetic protein (BMP)-ACVR1 developmental pat

181 sly, we demonstrated that transplantation of bone morphogenetic protein (BMP)-induced astrocytes deri

182 luence transcriptional regulation within the bone morphogenetic protein (BMP)-signaling pathway.

183 which is transcriptionally regulated by the bone morphogenetic protein (BMP)-SMAD pathway.

184 The bone morphogenetic protein (BMP)-SMAD signaling pathway

185 in chicken embryos to demonstrate a role for bone morphogenetic protein (BMP)/SMA and MAD related (Sm

186 The bone morphogenetic protein (BMP)/SMAD signaling pathway

187 ad2/3 pathway and activation of the parallel bone morphogenetic protein (BMP)/Smad1/5 axis (recently

188 was accompanied by changes in expression of bone morphogenetic protein (BMP)/sons of mothers against

189 ymatic activity, and six were members of the bone morphogenetic protein (BMP)/TGF-beta pathway.

190 Bone morphogenetic protein (BMP)4 is a mesenchymal pepti

191 es the gene encoding hepcidin (HAMP) via the bone morphogenetic protein (BMP)6 signaling to SMAD.

192 Bone morphogenetic protein (BMP)9 is a circulating growt

193 Exogenous bone morphogenetic proteins (Bmp) are well known to indu

194 subgroup of the TGFbeta superfamily are the bone morphogenetic proteins (BMP), but the effects of BM

195 Bone morphogenetic proteins (BMP), part of the TGFbeta s

196 thelial serine-threonine kinase receptor for bone morphogenetic proteins (BMPs) 9 and 10.

197 Bone morphogenetic proteins (BMPs) act in dose-dependent

198 glands are specified by mesenchymal-derived bone morphogenetic proteins (BMPs) and fibroblast growth

199 Bone morphogenetic proteins (BMPs) are antagonized throu

200 Bone morphogenetic proteins (BMPs) are growth factors th

201 Bone morphogenetic proteins (BMPs) are highly conserved

202 Bone morphogenetic proteins (BMPs) are members of the tr

203 Bone morphogenetic proteins (BMPs) are members of the tr

204 Bone morphogenetic proteins (BMPs) are secreted cytokine

205 Bone morphogenetic proteins (BMPs) are secreted growth f

206 Bone morphogenetic proteins (BMPs) are TGF-beta family m

207 Since the discovery of bone morphogenetic proteins (BMPs) as pluripotent cytoki

208 mbryo is regulated by graded distribution of bone morphogenetic proteins (BMPs) composed of two ligan

209 Subsequent treatment with bone morphogenetic proteins (BMPs) enhanced differentiat

210 Bone morphogenetic proteins (BMPs) have unexpectedly div

211 In Xenopus laevis, bone morphogenetic proteins (Bmps) induce expression of

212 Bone morphogenetic proteins (BMPs) instruct NSCs to adop

213 rcomes the inhibitory effect of lung-derived bone morphogenetic proteins (BMPs) on self-renewal and t

214 Bone morphogenetic proteins (BMPs) orchestrate key cellu

215 Bone Morphogenetic Proteins (BMPs) pattern the dorsal-ve

216 Bone morphogenetic proteins (BMPs) play key roles in the

217 Bone morphogenetic proteins (BMPs) play vital roles in r

218 Bone morphogenetic proteins (BMPs) regulate diverse cell

219 Bone morphogenetic proteins (BMPs) show promise in thera

220 Noggin is a specific antagonist of bone morphogenetic proteins (BMPs) that can prevent the

221 anoid cultures, such as those involving Wnt, bone morphogenetic proteins (BMPs), Notch, and Hedgehog

222 ignaling by Sonic hedgehog (SHH) followed by Bone morphogenetic proteins (BMPs), regulate a dynamic e

223 d in the nervous system as a co-receptor for bone morphogenetic proteins (BMPs).

224 fferentiate into preosteoblasts that produce bone morphogenetic proteins (BMPs).

225 operate locally (e.g., Wingless/Ints [Wnts], Bone Morphogenetic Proteins [BMPs], and Hedgehogs [Hhs])

226 AT reduces cleavage of the hepcidin inducing bone morphogenetic protein co-receptor HJV via inhibitio

227 C1s, sea urchin epidermal growth factor, and bone morphogenetic protein (CUB) domains of uncertain fu

228 l vein forms and expands ventrally through a Bone Morphogenetic Protein-dependent step of collective

229 channels regulate release of the Drosophila bone morphogenetic protein Dpp in the developing fly win

230 ifferent levels of activity of the canonical bone morphogenetic protein effectors SMAD1/5.

231 ignaling pathways, including Sonic hedgehog, bone morphogenetic protein, fibroblast growth factor, tr

232 ease inhibitor that binds growth factors and bone morphogenetic proteins, has nonsynonymous changes f

233 lated by Sonic hedgehog (Shh), retinoids, or bone morphogenetic proteins in the CNS, we provide evide

234 ilarly, wild-type (WT) animals, in which the bone morphogenetic protein-mothers against decapentapleg

235 niche signalling pathways, specifically Wnt, bone morphogenetic protein, Notch and epidermal growth f

236 Treatment with bone morphogenetic protein or SHH pathway inhibitors dec

237 GDF7 (rs3072), which encodes a ligand in the bone morphogenetic protein pathway, and TBX5 (rs2701108)

238 We analyzed the effect of Irf8 on TGF-beta/bone morphogenetic protein pathway-specific genes in DCs

239 hrough a nuclear factor kappaB/interleukin 6/bone morphogenetic protein pathway.

240 about Notch, transforming growth factor beta/bone morphogenetic protein, Ras, mitogen-activated prote

241 /or cocaine due to severe down-modulation of bone morphogenetic protein receptor (BMPR) axis: the ant

242 ce suggests that serotonin, mutations in the bone morphogenetic protein receptor (BMPR) II gene, and

243 e mutations leading to reduced expression of bone morphogenetic protein receptor (BMPR) II, these mut

244 The effect of a mutation in the bone morphogenetic protein receptor 2 (BMPR2) gene on ri

245 Because decreased expression and function of bone morphogenetic protein receptor 2 (BMPR2) is observe

246 terized by endothelial dysfunction, impaired bone morphogenetic protein receptor 2 (BMPR2) signaling,

247 inked to a mutation or reduced expression of bone morphogenetic protein receptor 2 (BMPR2).

248 g displays increased aromatase and decreased bone morphogenetic protein receptor 2 and Id1 expression

249 pproximately 20% concurrence of inactivating bone morphogenetic protein receptor 2 mutations and dela

250 Anastrozole treatment reversed the impaired bone morphogenetic protein receptor 2 pathway in females

251 expression may play a protective role in the bone morphogenetic protein receptor 2 unaffected carrier

252 itable PAH), most often through mutations of bone morphogenetic protein receptor 2, and idiopathic an

253 with hyperactivating mutations of the type I bone morphogenetic protein receptor ACVR1 (Activin type

254 zol-2-yl)benzamide] but not the inhibitor of bone morphogenetic protein receptor dorsomorphin, blocke

255 HT), which is caused by mutations in TGFbeta/bone morphogenetic protein receptor genes, ENG, encoding

256 However, transforming growth factor beta and bone morphogenetic protein receptor II signaling, and hy

257 role of transforming growth factor beta and bone morphogenetic protein receptor II signaling, human

258 ifferential transforming growth factor beta, bone morphogenetic protein receptor II signaling, or car

259 t beta1-integrin directly interacts with the bone morphogenetic protein receptor subunits BMPR1a and

260 Expression of bone morphogenetic protein receptor type 2 (BMPR2) and i

261 erozygous mutations in the gene encoding the bone morphogenetic protein receptor type 2 (BMPR2) are t

262 ith heritable PAH caused by mutations in the bone morphogenetic protein receptor type 2 (BMPR2) gene

263 l hypertension with germline mutation in the bone morphogenetic protein receptor type 2 (BMPR2) gene,

264 H (HPAH) is often caused by mutations in the bone morphogenetic protein receptor type 2 gene (BMPR2).

265 despite clinical and molecular similarity to bone morphogenetic protein receptor type 2 mutation-asso

266 Mutations in the gene encoding the bone morphogenetic protein receptor type II (BMPR2) are

267 Since the landmark discovery that bone morphogenetic protein receptor type II (BMPR2) muta

268 duced aggregation; 2) rs11202221, in BMPR1A (bone morphogenetic protein receptor type1A), replicated

269 rphogenetic proteins through VE-cadherin and bone morphogenetic protein receptor-II/Smad5.

270 e to maintain pluripotency in the absence of bone morphogenetic protein, removal of LIF destabilizes

271 53 activation; THR-184, a peptide agonist of bone morphogenetic proteins; removal of catalytic iron,

272 s of VBA, with and without recombinant human bone morphogenetic protein (rhBMP)-2, under space-making

273 In addition, the reduction in bone morphogenetic protein signaling and Shotgun express

274 ranase greatly stimulated chondrogenesis and bone morphogenetic protein signaling as revealed by Smad

275 However, inhibition of bone morphogenetic protein signaling caused a significan

276 nal profiling of isolated nail LRCs revealed bone morphogenetic protein signaling favors nail differe

277 eveal a novel role of TCF7l2 in repressing a bone morphogenetic protein signaling pathway that is kno

278 (Wnt), transforming growth factor-beta, and bone morphogenetic protein signaling pathways affect car

279 specific target genes upon Shh, retinoid, or bone morphogenetic protein signaling, and the collocatio

280 aranase is able to stimulate chondrogenesis, bone morphogenetic protein signaling, cell migration, an

281 Genes associated with bone morphogenetic protein signaling, such as bmp2, nog,

282 R/MEK/Erk1/2 signaling and downregulation of bone morphogenetic protein signaling, with negative and

283 ed either by erythroferrone or by inhibiting bone morphogenetic protein signaling.

284 8ORF1 could block TGF-beta signaling but not bone morphogenetic protein signaling.

285 dysregulated transforming growth factor beta/bone morphogenetic proteins signaling and that this imba

286 ing, and that ligandless activity in the TGF/bone morphogenetic proteins signaling pathway contribute

287 ar stress driven and downstream of canonical bone morphogenetic protein-SMAD signaling.

288 ic stress induces p57Kip2 expression via the bone morphogenetic protein-Smad1 and Atm-p38MAPK-Atf2 pa

289 These nonanticoagulant compounds impair bone morphogenetic protein /sons of mothers against deca

290 showed that loss of PEAT modestly increases bone morphogenetic protein target gene expression and al

291 hyperactive transforming growth factors beta/bone morphogenetic protein (TGFbeta/BMP) signaling in dK

292 es with sLR11 inhibits thermogenesis via the bone morphogenetic protein/TGFbeta signalling pathway an

293 phosphorylation was mediated by SMC-released bone morphogenetic proteins through VE-cadherin and bone

294 fferentially expressed genes were related to bone morphogenetic protein type 2 receptor (BMPR2) signa

295 ty of HPAH patients inherit mutations in the bone morphogenetic protein type 2 receptor gene (BMPR2),

296 Genetic evidence implicates the loss of bone morphogenetic protein type II receptor (BMPR-II) si

297 phagy and block lysosomal degradation of the bone morphogenetic protein type II receptor (BMPR-II), m

298 Mutations in the bone morphogenetic protein type-II receptor (BMPR-II) ar

299 Heterozygous germ-line mutations in the bone morphogenetic protein type-II receptor (BMPR-II) ge

300 yelin-forming oligodendrocytes is limited by bone morphogenetic proteins, which constitute one arm of