ライフサイエンスコーパス: bone morphogenetic protein 2

1 ge in the constitutive expression of Sox9 or bone morphogenetic protein 2.

2 ne marker genes including Sonic hedgehog and Bone morphogenetic protein-2.

3 broblast growth factor and bone-regenerating bone morphogenetic protein-2.

4 cification in response to increased P(i) and bone morphogenetic protein-2.

5 esence of transforming growth factor-beta or bone morphogenetic protein-2.

6 bitory mechanism is thought to be binding of bone morphogenetic protein-2.

7 ated that Tbx20, but not Tbx5, is induced by bone morphogenetic protein-2.

8 become an extracellular binding protein for bone morphogenetic protein-2.

9 been previously shown to bind TGF-beta1 and bone morphogenetic protein-2.

10 Nodal, bone morphogenetic protein 2/4 (Bmp2/4), and Six3-depend

11 phogen action during animal development, the bone morphogenetic protein 2/4 (BMP2/4)-like ligand Deca

12 This niche uses the bone morphogenetic protein 2/4 homolog, decapentaplegic,

13 legic (dpp), the Drosophila homolog of human bone morphogenetic protein 2/4, is expressed in anterior

14 al agents (norepinephrine, phenylephrine, or bone morphogenetic protein-2/4) or constitutively active

15 amily members in both TGF-beta, activin, and bone morphogenetic protein-2/-4 pathways.

16 Bone morphogenetic protein 2, a TGF-beta superfamily lig

17 ad 6 hours of goggle wear, downregulation of bone morphogenetic protein 2 and connective tissue growt

18 rum response element, which was augmented by bone morphogenetic protein 2 and transforming growth fac

19 e of growth factors and cytokines, including bone morphogenetic protein 2 and transforming growth fac

20 xpression of the Drosophila homologue of the bone morphogenetic protein-2 and -4 (BMP-2 and BMP-4) ge

21 Patched requires Sonic hedgehog but, unlike Bone Morphogenetic Protein-2 and Hox genes, does not req

22 ayer coating carrying as little as 200 ng of bone morphogenetic protein-2 and platelet-derived growth

23 Bone morphogenetic proteins 2 and 4 (BMP 2/4), potent os

24 hemojuvelin (HJV), is a co-receptor for the bone morphogenetic proteins 2 and 4 (BMP2 and BMP4) and

25 The bone morphogenetic proteins 2 and 4 are known to be impo

26 udied chondrogenic and osteogenic effects of bone morphogenetic proteins-2 and 4 and transforming gro

27 nals are secreted in both the mesoderm (e.g. Bone Morphogenetic Protein-2) and apical ectodermal ridg

28 programmed in response to increases in P(i), bone morphogenetic protein-2, and certain other stimuli.

29 en) matrix proteins and in the expression of bone morphogenetic protein 2 at a critical reparative ph

30 terms of osteoblastic differentiation using bone morphogenetic protein 2 (BMP-2) added to the medium

31 ved in early events of cardiogenesis such as bone morphogenetic protein 2 (bmp-2) and nkx-2.5 are exp

32 he complete signaling complex formed between bone morphogenetic protein 2 (BMP-2) and the extracellul

33 ic events, including increased expression of bone morphogenetic protein 2 (BMP-2) and the transcripti

34 ent a novel cell-signaling paradigm in which bone morphogenetic protein 2 (BMP-2) consecutively and i

35 at confluency results in >98% inhibition of bone morphogenetic protein 2 (BMP-2) expression and apat

36 d a positive effect of tissue-derived BGN on bone morphogenetic protein 2 (BMP-2) function, which is

37 Parbendazole up-regulates bone morphogenetic protein 2 (BMP-2) gene expression and

38 Bone morphogenetic protein 2 (BMP-2) initiates receptor-

39 Bone morphogenetic protein 2 (BMP-2) is essential for po

40 Although bone morphogenetic protein 2 (BMP-2) is known to stimula

41 Bone morphogenetic protein 2 (BMP-2) plays a critical ro

42 Treatment with bone morphogenetic protein 2 (BMP-2), which induces furt

43 we report that expression of TrkC suppresses bone morphogenetic protein 2 (BMP-2)-induced Smad1 phosp

44 sforming growth factor beta1 (TGFbeta1), and bone morphogenetic protein 2 (BMP-2).

45 EBs is accompanied by reduced expression of bone morphogenetic protein 2 (BMP-2).

46 rn blotting, respectively, for expression of bone morphogenetic protein 2 (BMP-2).

47 An important role for bone morphogenetic protein-2 (BMP-2) and insulin-like gr

48 st differentiation promoted and sustained by bone morphogenetic protein-2 (BMP-2) and TGF-beta, respe

49 We also identified bone morphogenetic protein-2 (BMP-2) as a candidate medi

50 tes osteoblast differentiation by increasing bone morphogenetic protein-2 (BMP-2) expression.

51 associated with increased expression of the bone morphogenetic protein-2 (BMP-2) gene in bone cells.

52 Bone morphogenetic protein-2 (BMP-2) has been implicated

53 recently reported the chondrogenic effect of bone morphogenetic protein-2 (BMP-2) in high density cul

54 The mechanism by which bone morphogenetic protein-2 (BMP-2) induces osteoblast

55 orming growth factor-beta superfamily member bone morphogenetic protein-2 (BMP-2) is up-regulated in

56 ment of neural crest stem cells (NCSCs) with bone morphogenetic protein-2 (BMP-2) leads to an inducti

57 This study examined the effects of bone morphogenetic protein-2 (BMP-2) on murine cementobl

58 ing the effects of TGF-beta family members - bone morphogenetic protein-2 (BMP-2) or BMP-4 and activi

59 Bone morphogenetic protein-2 (BMP-2) plays an important

60 rently, sustained in vivo delivery of active bone morphogenetic protein-2 (BMP-2) protein to responsi

61 The growth and differentiation factor bone morphogenetic protein-2 (BMP-2) regulates cardiac d

62 Bone morphogenetic protein-2 (BMP-2) regulates growth pl

63 Bone morphogenetic protein-2 (BMP-2) stimulates differen

64 s a prominent early response gene induced by bone morphogenetic protein-2 (BMP-2) through a Smad1/Run

65 ch as fibroblast growth factor-2 (FGF-2) and bone morphogenetic protein-2 (BMP-2) work synergisticall

66 ECFCs produced bone morphogenetic protein-2 (BMP-2), a potent osteoindu

67 Recent studies suggest that bone morphogenetic protein-2 (BMP-2), a transforming gro

68 ansforming growth factor beta-1 (TGFbeta-1), bone morphogenetic protein-2 (BMP-2), and BMP-6 were mea

69 x metalloproteinases 1 and 8 (MMP-1 and -8), bone morphogenetic protein-2 (BMP-2), receptor activator

70 Silk scaffolds were coupled with bone morphogenetic protein-2 (BMP-2), seeded with bone m

71 A combination of bone morphogenetic protein-2 (BMP-2), transforming growt

72 nce of occlusal loading on recombinant human bone morphogenetic protein-2 (BMP-2)-induced bone and ce

73 gulates differentiation of OCs downstream of bone morphogenetic protein-2 (BMP-2)-stimulated osteobla

74 its influence on osteoinductive activity of bone morphogenetic protein-2 (BMP-2).

75 been sequenced, over half have identity with bone morphogenetic protein-2 (BMP-2).

76 has also been identified as an inhibitor of bone morphogenetic protein-2 (BMP-2).

77 Another member of the TGFbeta superfamily, bone morphogenetic protein-2 (BMP-2; 100 ng/ml), did not

78 l with a collagen scaffold soaked in saline, bone morphogenetic protein-2 (BMP-2; 200 ng), 1 muM CGS2

79 ts which exhibit osteogenesis in response to bone morphogenetic protein-2 [BMP-2]), MG63 human osteob

80 se promoter was necessary and sufficient for bone morphogenetic protein 2- (BMP) and BMP4-dependent i

81 In the present study, bone morphogenetic protein-2/BMP-2-directed osteogenic d

82 sary for the induction of both TH and DBH by bone morphogenetic protein 2 (BMP2) (which induces Phox2

83 show that unexpected periodic expression of bone morphogenetic protein 2 (Bmp2) and Bmp4 in the derm

84 The expressions of bone morphogenetic protein 2 (BMP2) and BMP6; sex-determ

85 Recombinant forms of bone morphogenetic protein 2 (BMP2) and BMP7 are FDA app

86 study, we discovered the double deletion of bone morphogenetic protein 2 (Bmp2) and bone morphogenet

87 Cs) expressed significantly higher levels of bone morphogenetic protein 2 (BMP2) and demonstrated enh

88 We show that bone morphogenetic protein 2 (Bmp2) can stimulate cartil

89 ation of an injectable and porous nCS/A with bone morphogenetic protein 2 (BMP2) gene-modified MSCs a

90 Bone morphogenetic protein 2 (BMP2) in chromosomal regio

91 rentiate to autonomic neurons in response to bone morphogenetic protein 2 (BMP2) in clonal cultures,

92 The role of bone morphogenetic protein 2 (Bmp2) in regulating the tr

93 Here, we inactivated bone morphogenetic protein 2 (Bmp2) in the AV myocardium

94 Bone morphogenetic protein 2 (BMP2) plays a vital role i

95 Bone morphogenetic protein 2 (BMP2) promotes neuronal di

96 Bone morphogenetic protein 2 (BMP2) promotes PF formatio

97 In primary NC cultures, bone morphogenetic protein 2 (BMP2) requires moderate ac

98 nteractions between Sonic hedgehog (Shh) and bone morphogenetic protein 2 (Bmp2) signaling during fea

99 s mediated by combined cyclic AMP (cAMP) and bone morphogenetic protein 2 (BMP2) signaling.

100 We report here that the expression of the bone morphogenetic protein 2 (BMP2), a morphogen belongi

101 factors like core binding factor 1 (Cbfa1), bone morphogenetic protein 2 (BMP2), and BMP4; early mar

102 ules including all trans-retinoic acid, Shh, bone morphogenetic protein 2 (BMP2), and Wnt3A can direc

103 ral bone formation is triggered in muscle by bone morphogenetic protein 2 (BMP2), we studied changes

104 n of smooth muscle contractions by secreting bone morphogenetic protein 2 (BMP2), which activates BMP

105 t the inactivation of Cdc42 in NCCs impaired bone morphogenetic protein 2 (BMP2)-induced NCC cytoskel

106 umulation of phospho-Smad1, thus terminating bone morphogenetic protein 2 (BMP2)-induced sympathoadre

107 h prospective crista that corresponds to the Bone morphogenetic protein 2 (Bmp2)-positive domain in t

108 levated IOP animal model by gene transfer of bone morphogenetic protein 2 (BMP2).

109 actor 2 (RUNX2) activation and expression of bone morphogenetic protein 2 (BMP2).

110 Among them are Sonic hedgehog (SHH), Bone Morphogenetic Protein-2 (BMP2) and Bone Morphogenet

111 teogenic program that includes expression of bone morphogenetic protein-2 (BMP2) and the osteoblast h

112 al and temporal release of recombinant human bone morphogenetic protein-2 (BMP2) and vascular endothe

113 The heart-valve myocardium expresses bone morphogenetic protein-2 (Bmp2) coincident with deve

114 Although bone morphogenetic protein-2 (BMP2) has demonstrated ext

115 To address the function of bone morphogenetic protein-2 (BMP2) in mammalian develop

116 Cotreatment with Shh-N and bone morphogenetic protein-2 (BMP2) inhibited the anti-p

117 ostfertilization, and analyzed the effect of bone morphogenetic protein-2 (BMP2) on axial skeleton de

118 on of mesenchymal stem cells (MSCs), whereas bone morphogenetic protein-2 (BMP2) promotes osteogenic

119 d protein-1 (SMAD1) and SMAD4 in response to bone morphogenetic protein-2 (BMP2) signaling, which in

120 Bone morphogenetic proteins 2 (BMP2) and 4 (BMP4) regula

121 Using the complex structure of bone morphogenetic protein-2 bound to its type I recepto

122 Bone morphogenetic protein 2 (encoded by Bmp2) has been

123 ted the GH-dependent activation of IGF-1 and bone morphogenetic protein-2 expression.

124 ation of the 5'-flanking region of the human bone morphogenetic protein-2 gene.

125 In osteoblasts, CypA is necessary for BMP-2 (Bone Morphogenetic Protein-2)-induced Smad phosphorylati

126 estricted aggrecan), and for P(i) donor- and bone morphogenetic protein-2-induced calcification.

127 In addition, LRF also inhibited bone morphogenetic protein-2-induced chondrogenesis in h

128 BMP2 (bone morphogenetic protein 2) is a multifunctional membe

129 CTGF overexpression decreased the effect of bone morphogenetic protein-2 on Smad 1/5/8 phosphorylati

130 SMCs, including the calcification regulators bone morphogenetic protein 2, osteoprotegerin, and inter

131 We also found that stimulation by bone morphogenetic protein 2, platelet-derived growth fa

132 osteoclastogenic and inflammatory factors in bone morphogenetic protein 2 pretreated ATDC5 and C3H10T

133 niche consisting of a hydroxyapatite-coated, bone morphogenetic protein-2-releasing poly-L-lactic aci

134 ing sites on ALK4 and ALK3 for activin-A and bone morphogenetic protein-2, respectively.

135 to evaluate the effect of recombinant human bone morphogenetic protein 2 (rhBMP-2) associated with b

136 Recombinant human bone morphogenetic protein 2 (rhBMP-2) has been used for

137 hat of a positive control, recombinant human bone morphogenetic protein 2 (rhBMP-2), in the 8-mm rat

138 s by two concentrations of recombinant human bone morphogenetic protein-2 (rhBMP-2) delivered on a bi

139 r ovary (CHO) cell-derived recombinant human bone morphogenetic protein-2 (rhBMP-2) has been introduc

140 seous implants coated with recombinant human bone morphogenetic protein-2 (rhBMP-2) in a laboratory b

141 g surgical implantation of recombinant human bone morphogenetic protein-2 (rhBMP-2) in a novel hyalur

142 Recombinant human bone morphogenetic protein-2 (rhBMP-2) in a proper carri

143 ng of root surfaces during recombinant human bone morphogenetic protein-2 (rhBMP-2) induced periodont

144 Recombinant human bone morphogenetic protein-2 (rhBMP-2) is used as a bone

145 Recombinant human bone morphogenetic protein-2 (rhBMP-2) is widely used to

146 who had been treated with recombinant human bone morphogenetic protein-2 (rhBMP-2) loaded in an abso

147 Recombinant human bone morphogenetic protein-2 (rhBMP-2) technologies have

148 g surgical implantation of recombinant human bone morphogenetic protein-2 (rhBMP-2) using two novel s

149 as an effective carrier of recombinant human bone morphogenetic protein-2 (rhBMP-2).

150 d between nucleotides -687 and -253, whereas bone morphogenetic protein 2 sensitivity co-mapped withi

151 ptide nanostructures amplified signalling of bone morphogenetic protein 2 significantly more than the

152 ression in both rat chondrosarcoma cells and bone morphogenetic protein-2-treated C3H10T1/2 progenito

153 ith 3 days of goggle wear, downregulation of bone morphogenetic protein 2, vasoactive intestinal pept

154 ulate Tbx5 and Tbx20 expression, recombinant bone morphogenetic protein-2 was added to cardiogenic ex