ライフサイエンスコーパス: bone morphogenetic protein 4

1 sterior nephric duct, a process inhibited by bone morphogenetic protein 4.

2 sociated forms are capable of binding (125)I-bone morphogenetic protein-4.

3 ponse to transforming growth factor-beta and bone morphogenetic protein-4.

4 unterparts when exposed to TH, PDGF, or even bone morphogenetic protein-4.

5 sting of transforming growth factor-beta(1), bone morphogenetic protein-4, activin A, retinoic acid,

6 We further demonstrate that bone morphogenetic protein-4 acts as a mediator in oxida

7 anscription factors, whereas the activity of bone morphogenetic protein 4, an anti-branching molecule

8 Bone morphogenetic protein 4 and its mRNA were detected

9 phogenetic proteins and mRNAs examined, only bone morphogenetic protein 4 and its mRNA were present i

10 e been identified, including sonic hedgehog, bone morphogenetic protein 4 and multiple members of the

11 Contributions of bone morphogenetic protein 4 and transforming growth fac

12 ll differentiation, with Tshz3 downstream of bone morphogenetic protein 4 and upstream of myocardin a

13 es for hESC differentiated to TB by means of bone morphogenetic protein-4 and inhibitors of activin A

14 n retinal pigment epithelial cells, and both bone morphogenetic protein-4 and persistent mild oxidati

15 , implantation of a two-plasmid GAM encoding bone morphogenetic protein-4 and the parathyroid hormone

16 Bone morphogenetic proteins 4 and 7 (BMP4 and BMP7) are

17 rom Xenopus ectodermal explants, whereas the bone morphogenetic proteins 4 and 7 induce ectoderm to d

18 sequential applications of retinoic acid and bone-morphogenetic protein-4 and growth on collagen IV-c

19 al application of growth factors (Activin A, bone morphogenetic protein 4, and basic fibroblast growt

20 temporally and spatially with that of Bmp4 (bone morphogenetic protein 4), another target of Fgf10.

21 We have investigated the role of Bone Morphogenetic Protein 4 (BMP-4) and a BMP antagonis

22 gastrulation (Sog) antagonizing signaling by bone morphogenetic protein 4 (BMP-4) and Decapentaplegic

23 , we have shown that the ventralizing factor bone morphogenetic protein 4 (BMP-4) can inhibit Xenopus

24 ticular injection of murine MDSCs expressing bone morphogenetic protein 4 (BMP-4) in combination with

25 Previously, we elucidated the role of bone morphogenetic protein 4 (BMP-4) in the dorsal-ventr

26 own to down-regulate Smad1, MAPK may disrupt bone morphogenetic protein 4 (BMP-4) signaling during ne

27 t the expression of Lef1 can be activated by bone morphogenetic protein 4 (BMP-4) suggests a regulato

28 that were retrovirally transduced to express bone morphogenetic protein 4 (BMP-4) to differentiate in

29 ansduced with a retroviral vector to express bone morphogenetic protein 4 (BMP-4) were coimplanted wi

30 Lastly, bone morphogenetic protein 4 (BMP-4), a member of the tr

31 Recent results demonstrate that bone morphogenetic protein 4 (BMP-4), a member of the tr

32 may cause diffusion of the secreted molecule bone morphogenetic protein 4 (BMP-4), a neural inhibitor

33 factor (VEGF), the VEGF receptor 2 (Flk-1), bone morphogenetic protein 4 (Bmp-4), and the transcript

34 en this culture system was supplemented with bone morphogenetic protein 4 (BMP-4), the numbers of pri

35 thought to be triggered by the growth factor bone morphogenetic protein 4 (BMP-4).

36 d without retroviral transduction to express bone morphogenetic protein 4 (BMP-4).

37 the same stage, of regulatory genes such as bone morphogenetic protein-4 (BMP-4) and the Nkx2 family

38 Two signals are important in ventral cells, bone morphogenetic protein-4 (BMP-4) and Wnt-8.

39 Bone morphogenetic protein-4 (BMP-4) induces epidermis a

40 Bone morphogenetic protein-4 (BMP-4) is a multifunctiona

41 Bone Morphogenetic Protein-4 (BMP-4) is a potent epiderm

42 Pro bone morphogenetic protein-4 (BMP-4) is initially cleave

43 Bone morphogenetic protein-4 (BMP-4) is known to induce

44 Bone morphogenetic protein-4 (BMP-4) is synthesized as a

45 Bone morphogenetic protein-4 (BMP-4) is thought to play

46 effect of a sustained-release preparation of bone morphogenetic protein-4 (BMP-4) on EOM force genera

47 wed that exposure of C3H10T1/2 stem cells to bone morphogenetic protein-4 (BMP-4) produced cells that

48 the distal tips of the terminal buds, while bone morphogenetic protein-4 (Bmp-4) transcripts are loc

49 Mix.1 expression is induced by bone morphogenetic protein-4 (BMP-4), and a dominant inh

50 Here, we tested whether bone morphogenetic protein-4 (BMP-4)-treated or HOXB4-tr

51 These growth zones are associated with bone morphogenetic protein 4 (BMP4) activity.

52 By combining use of a hypomorphic Bone morphogenetic protein 4 (Bmp4) allele with conditio

53 RA-dependent induction in the mRNA levels of bone morphogenetic protein 4 (BMP4) and Decorin (DCN) in

54 ling controls the diencephalic expression of Bone morphogenetic protein 4 (Bmp4) and Fibroblast growt

55 Second, we used bone morphogenetic protein 4 (BMP4) and lunatic fringe (

56 Bone morphogenetic protein 4 (BMP4) and retinoic acid ar

57 We examined the role of bone morphogenetic protein 4 (BMP4) and WNT activation i

58 ntrated upstream of gene targets such as the bone morphogenetic protein 4 (BMP4) and zinc finger prot

59 Sonic hedgehog (Shh) and Bone Morphogenetic Protein 4 (BMP4) are expressed in dev

60 infection and transcript analysis identified bone morphogenetic protein 4 (BMP4) as a candidate endot

61 We identified bone morphogenetic protein 4 (BMP4) as one of these targ

62 he posterior expression of the gene encoding bone morphogenetic protein 4 (bmp4) but not of other kno

63 neutralization of the inhibitory activity of bone morphogenetic protein 4 (BMP4) by the BMP antagonis

64 The discovery that bone morphogenetic protein 4 (BMP4) can induce ventral m

65 aled that these tissues and their associated bone morphogenetic protein 4 (BMP4) did not contribute t

66 endently in the rudimentary otocyst based on Bone morphogenetic protein 4 (Bmp4) expression.

67 the antagonistic balance between noggin and bone morphogenetic protein 4 (BMP4) has a critical role

68 Bone morphogenetic protein 4 (BMP4) has potential as an

69 efined milieu revealed the essential role of bone morphogenetic protein 4 (BMP4) in determining the h

70 n of bone morphogenetic protein 2 (Bmp2) and bone morphogenetic protein 4 (Bmp4) in the dental epithe

71 Ectopic Shh suppressed expression of Bone Morphogenetic Protein 4 (BMP4) in the dorsal retina

72 Local application of bone morphogenetic protein 4 (BMP4) in the epithelium of

73 WMPCs also differentially expressed the bone morphogenetic protein 4 (BMP4) inhibitors neuralin

74 Bone morphogenetic protein 4 (Bmp4) is a crucial signali

75 We provide evidence that bone morphogenetic protein 4 (BMP4) is a mesenchymal fac

76 Bone morphogenetic protein 4 (Bmp4) is a multi-functiona

77 Bone morphogenetic protein 4 (BMP4) is a potent growth f

78 Bone morphogenetic protein 4 (BMP4) is crucial for the f

79 Bone morphogenetic protein 4 (Bmp4) is essential for lun

80 Bone morphogenetic protein 4 (Bmp4) is expressed during

81 human fetal skeletal muscle demonstrate that bone morphogenetic protein 4 (BMP4) is highly expressed

82 Bone morphogenetic protein 4 (BMP4) is known to regulate

83 Bone morphogenetic protein 4 (BMP4) is required for meso

84 genetic analysis in the mouse has shown that bone morphogenetic protein 4 (Bmp4) is required for the

85 egies, we provide evidence in the mouse that bone morphogenetic protein 4 (Bmp4) is required independ

86 y factor (LIF) together with either serum or bone morphogenetic protein 4 (BMP4) is sufficient to mai

87 response to transient (24-36 h) exposure to bone morphogenetic protein 4 (BMP4) plus inhibitors of A

88 In contrast, exogenous bone morphogenetic protein 4 (BMP4) reduced the producti

89 coprotein 1 (GLG1) expression and downstream bone morphogenetic protein 4 (BMP4) signaling and also r

90 The bone morphogenetic protein 4 (BMP4) signaling pathway pl

91 In this setting, Dies1 enhances bone morphogenetic protein 4 (BMP4) signaling.

92 es different concentrations of activin A and bone morphogenetic protein 4 (BMP4) to polarize cells in

93 secreted morphogens, only the expression of bone morphogenetic protein 4 (Bmp4) was increased in the

94 In this study, we demonstrate that bone morphogenetic protein 4 (BMP4), a factor known to b

95 Bone morphogenetic protein 4 (BMP4), a member of the TGF

96 Here we show that bone morphogenetic protein 4 (BMP4), a member of the tra

97 presumptive sensory organs initially express bone morphogenetic protein 4 (BMP4), a member of the tra

98 y epithelial cells and induces expression of bone morphogenetic protein 4 (Bmp4), a signaling molecul

99 Bone morphogenetic protein 4 (Bmp4), a vertebrate homolo

100 buccal gradient and restricted expression of bone morphogenetic protein 4 (Bmp4), an essential odonto

101 s associated with biomineralization, GATA-6, bone morphogenetic protein 4 (BMP4), and periostin were

102 er induction with combinations of activin A, bone morphogenetic protein 4 (BMP4), basic fibroblast gr

103 TGF-beta signaling mediated by pSMAD2, bone morphogenetic protein 4 (BMP4), EGF, or PDGF was un

104 that Fibroblast growth factor 10 (Fgf10) and Bone Morphogenetic Protein 4 (Bmp4), expressed in the di

105 tracellular ligands sonic hedgehog (Shh) and bone morphogenetic protein 4 (BMP4), have on histone ace

106 Consequently, bone morphogenetic protein 4 (BMP4), or ectopic expressi

107 als that regulate this process are Hedgehog, bone morphogenetic protein 4 (BMP4), stem cell factor an

108 Our results show that expression of Bone Morphogenetic Protein 4 (BMP4), the HMG box gene Le

109 Recent work has established that bone morphogenetic protein 4 (BMP4), the vertebrate homo

110 One candidate is Bone Morphogenetic Protein 4 (Bmp4), which is expressed

111 ransforming growth factor-beta family member bone morphogenetic protein 4 (BMP4), whose receptor is m

112 eport, we show that Friend virus induces the bone morphogenetic protein 4 (BMP4)-dependent stress ery

113 n to be induced by a secreted growth factor, Bone Morphogenetic Protein 4 (BMP4).

114 Submucosal smooth muscle cells express bone morphogenetic protein 4 (BMP4).

115 o become committed to the adipose lineage by bone morphogenetic protein 4 (BMP4).

116 own to promote beta-cell function, including bone morphogenetic protein 4 (BMP4).

117 rawal of leukemia inhibitory factor (LIF) or bone morphogenetic protein 4 (BMP4).

118 ted neural precursor cells (NPCs) exposed to bone morphogenetic protein 4 (Bmp4).

119 One of the factors is bone morphogenetic protein 4 (BMP4).

120 Patched (Ptc), intercellular signaling genes Bone Morphogenetic Protein-4 (Bmp4) and Noggin (Nog), an

121 ate that JNK initiates a cytokine cascade of bone morphogenetic protein-4 (BMP4) and sonic hedgehog (

122 s were mated with mice haploinsufficient for bone morphogenetic protein-4 (Bmp4) and their offspring

123 showed significantly increased expression of bone morphogenetic protein-4 (BMP4) associated with the

124 The secreted protein bone morphogenetic protein-4 (BMP4) has been identified

125 nsforming growth factor-beta2 (TGF-beta2) or bone morphogenetic protein-4 (BMP4) in an ALK2-dependent

126 Bone morphogenetic protein-4 (BMP4) may be involved in t

127 everal lines of evidence have suggested that bone morphogenetic protein-4 (BMP4) may be involved in t

128 Bone morphogenetic protein-4 (BMP4) plays a key role in

129 ells genetically engineered to express human bone morphogenetic protein-4 (BMP4), VEGF, or VEGF-speci

130 HH), Bone Morphogenetic Protein-2 (BMP2) and Bone Morphogenetic Protein-4 (BMP4).

131 Bone morphogenetic protein 4, BMP4, plays an important r

132 le protocol, using defined medium containing bone morphogenetic protein 4 by which human pluripotent

133 In this study we found that the bone morphogenetic protein 4-dependent (BMP4-dependent)

134 ed that sublethal oxidative stress increased bone morphogenetic protein-4 expression in retinal pigme

135 and Twist but derepresses expression of the bone morphogenetic protein-4 gene.

136 ndidate gene approach, we analyzed the BMP4 (Bone Morphogenetic Protein-4) gene and identified a fram

137 Specification of these progenitors with bone morphogenetic protein-4 in combination with basic f

138 most important findings include the role of bone morphogenetic protein-4 in morphogenesis of the kid

139 ression of a potent bone-inducing morphogen (bone morphogenetic protein 4) in lymphocytes is associat

140 Activin-A and bone morphogenetic protein 4-induced cardiovascular prog

141 In addition, we also show that bone morphogenetic protein 4 is a downstream target gene

142 We demonstrate here that bone morphogenetic protein-4 is highly expressed in the

143 Bmp4 (bone morphogenetic protein 4) is one of two loci that se

144 ur results suggest that oxidative stress and bone morphogenetic protein-4 may interact to promote ret

145 pigment epithelial cell senescence and that bone morphogenetic protein-4 may represent a novel thera

146 Bone morphogenetic protein 4 mRNA was expressed in lymph

147 be blocked by Chordin-like, an antagonist of bone morphogenetic protein-4, or SB203580, a phospho-p38

148 is identified Xom, a homeobox protein of the bone morphogenetic protein 4 pathway, as a novel LEF/TCF

149 Sequential coculture with bone morphogenetic protein 4, PGE2, and SR1 led to robus

150 Implantation of a GAM containing either a bone morphogenetic protein-4 plasmid or a plasmid coding

151 and reproducible specification protocol with bone morphogenetic protein 4, prostaglandin-E2 (PGE2), a

152 er in directing differentiation, the role of bone morphogenetic protein-4 signaling in smooth muscle

153 Bone morphogenetic protein 4 up-regulated alphaB-crystal

154 e framework whereby activation of TGF-beta2, bone morphogenetic protein 4, Wnt/beta-catenin, or immun