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1 with moderate to severe PS, 10 subjects with both AD and CD, and 10 HC with no history of skin diseas

2 with higher working-age male mortality rates both between 1992 and 1998 (age-standardised mortality r

3 roteins showed the same changing patterns in both 1 SL and 2 SL.

4 ide significant in a meta-analysis including both identification and 4 verification cohorts (P < 2.19

5 i images compared with whole-body images for both (68)Ga-DOTATOC and (68)Ga DOTATATE.

6 The majority of MIs in both time periods (74% and 76%) were not related to sten

7 e of binding sites have been evaluated using both a distance and a volumetric overlap approach.

8 We speculate that micromolar H2O2 is created both biologically and abiotically at natural oxic/anoxic

9 ition states (DeltaDeltaE(double dagger)) in both the presence and absence of the counterion.

10 dala that receives afferent projections from both the main and accessory olfactory bulbs.

11 ion between activity and movement was stable both over time and across VR environments.

12 ulatory variation in individual yeast cells, both before and after stress.

13 hallenge with individual virulent serotypes, both in early challenge and after 5 months of challenge

14 nduced surface expression of E-selectin, and both ALK1 and ALK2 in the up-regulation of VCAM-1 and IC

15 binding competence toward alphaVbeta3 (using both isolated receptors and alphaVbeta3-overexpressing e

16 on yet, brown lentil seems to have potential both as a starch and also as a resistant starch source.

17 ta depletion resulted in rapid deployment of both a pro-inflammatory and an immunosuppressive respons

18 (ii) Selective and cooperative binding of both an acetato ligand and an amino ligand to zinc occur

19 ociated with a significantly reduced odds of both atopy and "any allergic condition" (adjusted OR AOR

20 orrelation coefficient =0.931; P<0.001) over both iterative and aortic velocity-time integral methods

21 YY1 acts both as a repressor and as an activator of gene expressi

22 Both Husk and Ash provided K, which also played a role i

23 s and process considerations of their use in both kinetic resolution and asymmetric synthesis.

24 time-dependent dissociation and the loss of both DHO and ATC activities.

25 Both obesity and atrial fibrillation (AF) are increasing

26 ACT: Ethanol, like other drugs of abuse, has both rewarding and aversive properties.

27 These bacteria mineralize both arsenic and barium on intracellular vesicles.

28 Both mitochondrial and barrier defects were largely corr

29 nal endothelium and coordinate the timing of both vascular pruning and barrier maturation.

30 provide critical assessments of disease for both clinical and basic science imaging research studies

31 's central rich club (RC) system relative to both control subjects and BD offspring.

32 ed compounds with only beta-O-4 linkages, or both 5-5 and beta-O-4 linkages, showed major 1,2-elimina

33 stereoselective route in six steps; however, both alpha and beta epimers could be obtained by a nonst

34 highlights the importance of selecting from both chemo- and biocatalysts for optimal results.

35 PET) and computed tomography (CT) can assess both anatomy and biology of carotid atherosclerosis.

36 ristics and hospital courses were similar in both groups, and birth weights ranged from 580 to 1495 g

37 dence interval (CI) 1.89-9.21] compared with both nulliparity (reference) and breastfeeding.

38 -) mice display abnormal fat accumulation in both white and brown adipose tissues, glucose intoleranc

39 In the BOO group at day 10, the SAAs of both Adelta- and C-fibers at the "ascending" phase of mi

40 amolecular amidation and the construction of both C-C and C-N bonds.

41 er molecule that is an upstream regulator of both IkappaB kinase (IKK) and c-Jun N-terminal kinase (J

42 We find that both the N- and C-terminal domains of TTP are involved i

43 vegetative growth in the wild progenitors of both C3 and C4 founder crops.

44 ts with distinct immunological properties in both healthy individuals and cancer patients.

45 The benefits of land sparing for both biodiversity and carbon storage suggest that safegu

46 ) calculations on these reactions, involving both cyclopentadienyl and carboranyl ligands on the meta

47 ne secretion observed at high Ag density for both TCRs and CARs suggested a role for negative regulat

48 major topoisomerase for mRNAs, and requires both RNA binding and catalytic activity to promote neuro

49 stationary phase allowed fast separation of both individual lipid species and categories.

50 We find that naive hPSCs robustly engraft in both pig and cattle pre-implantation blastocysts but sho

51 Here, we further stabilized pre-F by adding both disulfide and cavity-filling mutations (DS-Cav1), a

52 (CCR6(+)), and particularly those expressing both CXCR3 and CD161 were reduced most significantly, wh

53 pes in the V3-loop and trimer base, minimize both CD4 reactivity and CD4-induced non-nAb epitope expo

54 Additionally, both CD8(+) T cells and CD8(+) dendritic cells were iden

55 s of abnormal amphibians are associated with both parasite infection and chemical contaminants, but t

56 tant role of sulfate in tracer formation via both physical and chemical mechanisms.

57 or responses in the inflammatory contexts of both acute infection and chronic autoimmunity in mice.

58 will allow for informed decision making for both apple producers and cider makers.

59 g CVVH there was a substantial net uptake of both glucose and citrate that delivered exogenous energy

60 global scale, with negative consequences for both provisioning and climate regulating ecosystem servi

61 This platform will greatly benefit both researchers and clinicians for interrogating mechan

62 Five macroalgal species capable of using both HCO3(-) and CO2 had greater CO2 use as concentratio

63 ined on the desalted serum sample spots show both good reproducibility and compare well to results fr

64 function of temperature and of pressure, as both are equally important and complementary thermodynam

65 artite interface between synaptotagmin-1 and both the SNARE complex and complexin.

66 g as a deAMPylation enzyme, its activity was both time- and concentration-dependent.

67 properties of Granger-Geweke (GG) causality, both computational and conceptual.

68 lability (that is, [(11)C]ABP688 binding) in both MDD and control subjects (average of 14+/-9% and 19

69 Both maternal and cord serum samples were assayed for le

70 fferent bacterial phyla and varies widely in both protein sequence and corresponding crRNA sequence c

71 Surgery was both effective and cost-effective for obese patients wit

72 es relative to a common warhead scaffold, in both noncovalent and covalent binding states, and for tw

73 ervations demonstrate that the production of both nuclear and cytoplasmic Esrp1 isoforms through alte

74 characterize the magnetosome arrangement in both wild-type cells and DeltamamJ mutants, which exhibi

75 hing them to dynamic microtubule ends during both polymerization and depolymerization of tubulin.

76 ng the relationship between the vitreous (in both its attached and detached state) and the internal l

77 In the cerebellum, both compensatory and detrimental contributions seem to

78 the relative GLP-1 vs glucagon production in both non-diabetic and diabetic islets, suggesting a posi

79 SEP was associated with higher adult BMI in both genders, and differences were typically larger at o

80 hromatin-remodeling enzymes, is required for both myoblast proliferation and differentiation, and the

81 n a novel delay-based task that incorporates both predictable fluctuations and directional shifts in

82 the functioning of host organisms, affecting both health and disease.

83 ates essential aspects of Ca signaling under both normal and diseased conditions.

84 iRNAs crucial for cell identity by enhancing both transcription and Drosha/DGCR8-mediated primary miR

85 livery vesicles, controlling liposome shape (both statically and dynamically) is of utmost importance

86 This shows that both conformational rigidity and dynamics are essential

87 Recent evidence suggests value for both selective drain placement and early drain removal f

88 utant cells from the tissue, while utilizing both endogenous and ectopic cellular behaviours to disma

89 Considering uncertainty in both cost and effect using a wide range of willingness t

90 of the art measurement techniques which are both sensitive and efficient.

91 were also greater in Loda than HS93-4118 at both ambient and elevated [CO2 ].

92 ent may thus constitute a common endpoint of both EMT-dependent and EMT-independent cancer disseminat

93 ment (SWM) systems requires consideration of both economic and environmental impacts.

94 ) and the kinase inhibitory activity (toward both isolated kinases and EPCs) remained almost untouche

95 st, cFos expression was similarly reduced by both PS and ES.

96 onary science of culture that is grounded in both biological and evolutionary theory, but also treats

97 Here, we provide both observational and experimental support of critical

98 ter/hydrophobe (e.g., air/water) interfaces, both computer simulations and experiments have shown tha

99 oss after 6 months was -0.25 BMI z scores in both PBT and FBT.

100 of IgG1 and IgG3 specific for MSP119, MSP2 (both allelic families, 3D7 and FC27), MSP3, GLURP (both

101 APP from the Glu(11) site to the Asp(1) site both in male and female transgenic mice in vivo and in c

102 dysfunction and breathing irregularities, in both male and female mice.

103 lls that produce more inflammatory cytokines both at baseline and following endotoxin exposure when c

104 To study changes in both retinal structure and function during the first mon

105 R neurons recruit both GABA and GABA-A receptors to their axon terminals i

106 The pairing of both loss- and gain-of-function datasets reveals complex

107 by transfer of radiolabels into product from both alpha and gamma phosphates of donor molecules.

108 Relative to oxidation of Fe(II)(aq) alone, both goethite and gamma-Al2O3 surfaces increased Fe(II)

109 lution data in a framework that incorporates both solution chemistry and geometric constraints on the

110 Therefore, we show that both habit-like attention and goal-directed processes oc

111 OCT detected progression earlier than VF in both PG and GS/PPG groups.

112 ing total T cells, T-helper and CTLs against both H1N2 and H1N1 SwIV.

113 y and present smaller enthalpic barriers for both epoxidation and H2O2 decomposition reactions.

114 llow ASF1A to form a quaternary complex with both sNASP and H3-H4.

115 An unprecedented solvent-directed "switch" both in helical pattern and handedness was observed when

116 obabilistic category learning performance in both CD and HC.

117 of viral and cellular replication cycles in both photoautotrophic and heterotrophic bacterial hosts.

118 an important role in vesicle recruitment in both low- and high-frequency hair cells.

119 Both organic farming and higher in-field plant diversity

120 n extensive perturbations of the dynamics in both apo- and holo-forms of the HCN4 isoform, reflecting

121 This has now been corrected in both the PDF and HTML versions of the article.

122 In both mouse and human B cells, BCR ligands that deliver a

123 Using the Transwell system, both murine and human monocytes sorted with magnetic bea

124 role that ACSL6 plays in lipid synthesis in both rodent and human skeletal muscle.

125 ion causes a severe global health concern to both ecosystem and humanity.

126 rn, exacerbate ethanol-induced liver disease both in mice and humans.

127 During pressure overload, both hypertrophic and hypoxic signals can stimulate angi

128 Both imatinib-sensitive and imatinib-resistant Kit (Kit(

129 tein concentrates (WPC) were hydrolyzed with both free and immobilized enzyme, reaching a similar deg

130 g of sex-specific cardiovascular differences both at baseline and in disease is required to effective

131 udies have revealed how editing is regulated both in cis and in trans.

132 by repeated measurements over hours and days both in phantoms and in vivo.

133 y is distinct from average spatial distance, both in polymer simulations and in experimental data.

134 en demonstrated to reduce amyloid deposition both in vitro and in vivo Because N-terminally truncated

135 ale robots have the potential to be used for both in vitro and in vivo biomedical applications.

136 induce efficient apoptotic cancer cell death both in vitro and in vivo through tumor-specific (1) O2

137 lated CCSCs (93% accuracy) were employed for both in vitro and in vivo tumor phenotyping to identify

138 triggered by a decrease in hDBR1 expression both in vitro and in vivo.

139 etter assess biomaterial-tissue interactions both in vitro and in vivo.

140 r odonto/osteogenic differentiation of DPSCs both in vivo and in vitro.

141 o the formation of Ang-(1-7) from Ang II, in both normal conditions and in disease states, remains on

142 ced capacity for HR-mediated gene conversion both spontaneously and in response to I-SceI-induced DSB

143 Ab (VHH or nanobody) significantly inhibited both phosphoantigen-dependent and -independent activatio

144 On the basis of its ability to both attract and induce virulence gene expression in EHE

145 uch intraplate earthquake localization, with both natural and induced seismicity generally clustered

146 Although both persistent itch and inflammation are commonly assoc

147 receptor CD6 regulates T cell activation in both activating and inhibitory manners.

148 s in the duodenal mucosa as a consequence of both adaptive and innate immune responses to undigested

149 dels in fact well predict observed levels of both intra- and interhost variability.

150 ove were comparatively appraised in terms of both functional cohesion and intra-subnetwork associatio

151 rugs already approved by the FDA, can reduce both tumor size and invasiveness and could lead to tumor

152 Both the outward and inward K(+) currents shifted Veq K(

153 ent a photonic crystal device which performs both tasks simultaneously and is able to couple light at

154 es a genome-wide method capable of capturing both gene expression levels and isoform diversity at the

155 with dual activity for effectively blocking both AMPA and kainate receptors.

156 te RNA aptamers that can potentially inhibit both AMPA and kainate receptors.

157 nted for by temperature-dependent changes in both Km and kcat (three substitutions) or either Km or k

158 Megalin expression was about the same in both WT and KO mouse visceral yolk sac, brain, and spina

159 esults in a predicted ZT as high as 1.5 for both La3Cu3P4 and La3Cu3As4, under high p-type doping.

160 allowing determination of ligand selectivity both for small drugs and large proteins with nearly base

161 ization of the complete RNA cargo, including both small- and long-RNAs, in a single library preparati

162 nostication and their relation with HRQoL in both the short and longer term.

163 be crucial in dominant diseases that feature both gain- and loss-of-function pathologies or have a he

164 that PAG microglia are sexually dimorphic in both basal and LPS-induced activation and contribute to

165 PtabZIP1L suppression significantly delayed both LRP and LR formation.

166 ripheral blood mononuclear cells (PBMC) from both humans and macaques was increased following the exp

167 ced metamagnetic-like transition and affects both magnetisation and magnetostriction, the low field a

168 nd prostate) and lung and colon tissues from both female and male mice.

169 vesicles with lipid compositions that mimic both bacterial and mammalian cell membranes.

170 nnovative technique for training students in both effective interprofessional communication and manag

171 er, Ulocladium strains were shown to possess both MAT1-1-1 and MAT1-2-1 genes as observed in homothal

172 Here, we review advances in engineering both imaging modalities and material properties with imp

173 Both flux decline and membrane scale formation decreased

174 te tissue types, but existing approaches are both CPU and memory-intensive, limiting their applicatio

175 Our findings were validated in both primary and metastatic models of pancreatic cancer.

176 First, both PD patients and mice with ventral tegmental area (V

177 e association was significant among cases of both severe and mild acute pancreatitis.

178 Both PCR-based and MLVA methods are limited in discrimin

179 ngi enhanced plant nutrient acquisition with both lower and more variable water availability, for ins

180 Our calculations indicate that both UQ and MQ have low redox potentials around -260 and

181 Both BioRoot and MTA Fillapex showed cytotoxicity which

182 n important role in murine asthma, mediating both AHR and mucus secretion after HDM exposure.

183 exhibited the poorest clinical prognoses on both univariable and multivariable analyses accounting f

184 tation (Gfap(R236H)(/+)) (and thus expresses both wild-type and mutant protein).

185 (S34F) can be cumulative in cells exposed to both perturbations-drug and mutation-compared with cells

186 n between two images in rivalry is driven by both attentional modulation and mutual inhibition, which

187 Both n-6 and n-3 polyunsaturated fatty acids are associa

188 mart carriers for multiple cargos, including both naked and nanoparticle-encapsulated chemotherapeuti

189 In both cases, resonant plasmonic and nanophotonic structur

190 e been optimized to migrate appropriately on both agarose and native polyacrylamide, unlike many curr

191 r 20-hydroxyeicosatetraenoic acid, which has both vasoconstrictive and natriuretic actions.

192 ral immobility and rest has been linked with both memory consolidation and navigational planning.

193 nd better the immunologic factors underlying both original antigenic sin and negative antigenic inter

194 Here we demonstrate both behavioral and neural correlates of looming bias wi

195 ness to internal and external circumstances; both the rhythm and neuromodulatory responses of breathi

196 -tetramethyl-1-piperidinol (SA-2) containing both antioxidant and NO donor functionalities that provi

197 More than half of physicians (61% from both accommodation states and non-accommodation states)

198 ge-adjusted incidence of HPV-related cancer (both cervical and non-cervical) in all women in England

199 Thus, the ASCC3 gene expresses both coding and non-coding transcript isoforms with oppo

200 ented SNS and haemodynamic reactivity during both combat-related and non-combat related mental stress

201 neutrophils infiltrated CXCL-8(+) DLBCL from both germinal center (GC) and non-GC subtypes.

202 oach to monitor the position and dynamics of both repetitive and non-repetitive genomic regions in li

203 The network utilized both reward modulated and non-reward modulated STDP and

204 eas their strongly destabilized mutants form both amyloids and nonamyloid aggregates.

205 r protein sorting 34 (Vps34) plays a role in both canonical and noncanonical autophagy, key processes

206 The auxin effector ARF5/MONOPTEROS (MP) acts both cell-autonomously and noncell-autonomously to contr

207 ders of magnitude in seed size and including both dormant and nondormant seeds.

208 normal-appearing white matter (P < .001 for both contrast-enhancing and nonenhancing regions).

209 enables the study of biological processes in both living and nonviable systems at the molecular level

210 le thermal expansion of a suspended resistor both theoretically and experimentally and obtained consi

211 contact survey in Hong Kong in 2015/16 using both paper and online questionnaires.

212 However, it remains unclear how LAP shapes both the activation and outcome of the immune response a

213 To address the role of CGRP both within and outside the CNS, we used CGRP-induced li

214 d doxorubicin were observed in vitro against both multiple myeloma and ovarian cancer cells.

215 g in SBMA muscles and induced hypertrophy of both glycolytic and oxidative fibers.

216 i film are controlled at low concentrations (both B and P are less than 1 ppm).

217 populations that transmit information about both innocuous and painful touch and inhibitory populati

218 CaMKI is required and serves as both a PINK1 and Parkin kinase.

219 via small molecule signals is important for both symbiotic and pathogenic relationships, but is ofte

220 urvival/death, and cellular metabolism under both physiological and pathological conditions.

221 is expressed in reactive cholangiocytes, in both murine models and patients with PSC.

222 cell carcinoma.Among older American adults, both nut and peanut butter consumption were inversely as

223 in the evolution of vocal communication, in both production and perception.

224 a novel GPx1 mimic, has been shown to reduce both temporary and permanent noise-induced hearing loss

225 formation, which play a key role in defining both selectivity and permeation.

226 ugs and selected those reporting results for both OS and PFS.

227 r is diffusion driven for surface electrons, both diffusion and phonon drag contributions are essenti

228 raphene foil is designed and constructed for both electrochemical and photoelectrochemical water spli

229 f applicability of molecular docking to show both enantioselective electrochemical and photoluminesce

230 Critically, reward devaluation by both cognitive and physical effort was subserved by a co

231 nsiently reduced in whole blood samples from both omalizumab- and placebo-treated subjects.

232 FP promoted atherogenic lipid metabolites in both the intestine and plasma via altered gut microbiota

233 ody palivizumab, which recognizes site II on both the pre-F and post-F proteins, is restricted to pro

234 tion, as well as downstream misregulation of both pre- and postsynaptic molecular assembly.

235 pounds while other mammals contain PFOS from both direct exposure and precursor degradation.

236 nd outperform several established methods in both computational efficiency and prediction accuracy.

237 duce differing outcomes-loss of p53 promotes both tumor initiation and progression; loss of Arf promo

238 e external inorganic carbon concentration at both the transcript and protein levels.

239 llelic families, 3D7 and FC27), MSP3, GLURP (both regions, R0 and R2), and AMA1 antigens of Plasmodiu

240 Solitary perturbations (SPs) localized both poloidally and radially are detected within 100 mu

241 R1 levels while male mice show reductions in both ligand and receptor expression.

242 "experiment of nature" in monozygotic twins both prevented anemia and reduced HSP90 binding.

243 The reaction is both chemo- and regioselective, as only 4,6-disubstitute

244 oughout the dermis and epidermis and control both the functional and reparative capacity of the skin.

245 l amygdala (BLA) impaired the acquisition of both conditioned fear extinction and response-outcome co

246 This resulted from both N-domain twisting and rotation of the C domain (up

247 We benchmark Structure-seq2 on both mRNA and rRNA structure in rice (Oryza sativa).

248 imicrobial peptide in vitro, inactivation of both phoP and Sant_4061 is necessary to abrogate growth

249 alcium gradients and intracellular fluxes in both the cytoplasm and sarcoplasmic reticulum.

250 extract this information, we propose fitting both first and second scans simultaneously.

251 We found substantial derangements in both neuronal excitability and short-term synaptic plast

252 ion of LHGs, different types of amphiphiles (both polymer and small-molecule surfactants) were guided

253 printing strategy for biosensors facilitates both rapid development and small-scale manufacturing.

254 these two strategies would likely result in both effective and specific cancer therapy.

255 A significant decrease in both keratometry readings and spherical equivalent (from

256 in or spinal (43.4pg/ml, IQR = 25.2-65.3) or both brain and spinal gadolinium-enhancing lesions (62.5

257 Both layer and sponge cakes exhibited an enhancement of

258 aFeO2.5)1 thin film superlattices possessing both anion-vacancy order and Sr and Ca chemical order at

259 Ambra1 binds to both FAK and Src in cancer cells.

260 Both APP and ST-when completed-increased the use of peni

261 bjectively, rapidly and reproducibly measure both size and stability of the intervening chromatin loo

262 the examples resulting from these efforts in both inhibiting and stabilizing specific 14-3-3 protein

263 s for alkylations has become attractive from both cost and sustainability viewpoints.

264 nteractions between cells and biointerfaces, both natural and synthetic.

265 d the protective actions of these statins on both joint and systemic inflammation.

266 Meanwhile, both RanBP9 and tau levels are simultaneously reduced by

267 Both physical and technical aspects of correlative image

268 ply that each of these magmatic systems were both spatially and temporally distinct.

269 analysis of large RNA-Seq data sets requires both careful quality control and the need to account for

270 are urgently needed to significantly reduce both mortality and the healthcare costs associated with

271 larmin family has been expanding in terms of both number and the concept.

272 T) methods all predict linear geometries for both the anions and the neutral radicals.

273 e found that Munc18c, like Munc18a, binds to both the closed conformation and the N-peptide of Syx4.

274 n of mPFC output is causally correlated with both the cognitive and the sensory component of neuropat

275 AtBAG7 has functional roles in both the ER and the nucleus.

276 ferentiated cells differ quantitatively from both the starting cells and the target cells.

277 For comparison, both the STP and the STOK techniques were used to genera

278 Both the preprotein MTSs and their receptor site on SecA

279 lid-state explosive reactions are built upon both thermodynamics and kinetics, and then successfully

280 Both experimental and theoretical results agree that ZnC

281 h serine proteases are found ubiquitously in both eukaryotes and prokaryotes, and they comprise the l

282 ting by tilt, and gating by a combination of both dilation and tilt.

283 mplement factor H (CFH) are also features of both ARMD and TMA, we hypothesized that VEGF and CFH int

284 o quantify intermediary metabolism fluxes in both sedentary and treadmill-running mice.

285 ells impaired CCL2 production and diminished both lung MDSC presence and tumor growth.

286 umber of neuropeptide signaling systems with both oncogenic and tumour-suppressing roles for cancer p

287 ty member and principal investigator (PI) as both unattainable and undesirable.

288 ole of roughness in colloid attachment under both favorable and unfavorable conditions.

289 f inflammation, angiogenesis, and the ECM to both "healthy" and "unhealthy" AT expansion.

290 on-specific effects of each drug, suggesting both common and unique effects of imipramine versus keta

291 networks of bacterial interactions revealed both common and unique features in milk niches.

292 osulfurization and guanylation could lead to both symmetric and unsymmetric N,N',N''-substituted deri

293 tion of measles cases changes in response to both demographic and vaccination processes.

294 ows this short motif to be bound directly by both CPSF-30 and WDR33.

295 iron concentration than wild-type plants in both brown and white grains.

296 comprising the catalytic domain can interact both with itself and with a C-terminal fragment.

297 Both without and with confirmatory testing, LE was 26.2

298 We then compared trajectories through maps both with and without high-order epistasis.

299 ation and that client interactions can occur both with and without oligomer dissociation.

300 Loss of both RECQL5 and WRN severely compromises DNA replication