ライフサイエンスコーパス: both sexes

1 europrotection in an AD model of Drosophila (both sexes).

2 on oligodendrocytes under normal conditions (both sexes).

3 the PA and FFM obtained with the use of UWW (both sexes).

4 bottom 5% (P < .001 for the differences for both sexes).

5 ribosome affinity purification (TRAP) mice (both sexes).

6 at express IFN-gamma ectopically in the CNS (both sexes).

7 rom white-matter voxels, in 176 subjects (of both sexes).

8 the environment and shorten the lifespan of both sexes.

9 and significantly reduces insulin release in both sexes.

10 H-HCC) murine model and compared results for both sexes.

11 ed hippocampal neurons from mice and rats of both sexes.

12 emergence of incubation of heroin craving in both sexes.

13 ry experience has on this process in mice of both sexes.

14 aromatase mRNA and activity were elevated in both sexes.

15 , reflected by increased white cell count in both sexes.

16 re in cultured cortical neurons from rats of both sexes.

17 The lifetime risk was similar (>30%) for both sexes.

18 further selection and was equally strong in both sexes.

19 ostmetamorphic specimens and young adults of both sexes.

20 mortem brains of sporadic PD/PDD patients of both sexes.

21 ce optic nerve regeneration in adult rats of both sexes.

22 s the ryanodine receptor, induces priming in both sexes.

23 ificantly increased among all age groups and both sexes.

24 heritable variation in recombination rate in both sexes.

25 aptic connections between neurons present in both sexes.

26 ellar computations, we studied it in mice of both sexes.

27 ) may be provided by females, by males or by both sexes.

28 s were equally likely to predict an event in both sexes.

29 arity be addressed so that therapies benefit both sexes.

30 risk of conviction for a violent offense in both sexes.

31 rbidities add to the amount of disability in both sexes.

32 dominant mutation that benefitted females or both sexes.

33 ce, whereas cortical osteopenia persisted in both sexes.

34 tiate glutamatergic synaptic transmission in both sexes.

35 shown between the PA and ECW:ICW ratios for both sexes.

36 alizations in the paraventricular nucleus of both sexes.

37 results were strain independent and seen in both sexes.

38 raint predicted a greater 2-y weight loss in both sexes.

39 36% more likely than mandibular agenesis in both sexes.

40 vaccines for use starting at age 9 years for both sexes.

41 o other strains of rats, as well as mice, in both sexes.

42 in patients without LBBB were attenuated in both sexes.

43 termined for children of different sizes and both sexes.

44 , plep-1, expressed in the excretory cell in both sexes.

45 rs formed at comparable levels and ratios in both sexes.

46 d 18 infections at other anatomical sites in both sexes.

47 The associations were similar in both sexes.

48 ference to estimate SM and adipose tissue in both sexes.

49 vers were obtained at similar frequencies in both sexes.

50 nd lipid-lowering drugs also increased among both sexes.

51 ine in standarized incidence ratio (SIR) for both sexes.

52 new cases and rates of PLC are projected in both sexes.

53 explain the evolution of elaborate traits in both sexes.

54 Deficits in social behavior were observed in both sexes.

55 y CT examinations for all age groups and for both sexes.

56 a dissimilarity in screening outcome between both sexes.

57 ractice of generalizing data from one sex to both sexes.

58 , and between years there was a tendency for both sexes.

59 able therapeutic approach for MS subjects of both sexes.

60 therapeutic targets to restore breathing in both sexes.

61 e neural underpinning of the decoy effect of both sexes.

62 r external granule layer of P2 mouse pups of both sexes.

63 le HLT and PT fracture sites, consistent for both sexes.

64 ecific differentiation of neurons present in both sexes.

65 associated risk of HPR for ST was similar in both sexes.

66 espite their likely impact on the fitness of both sexes.

67 tion to oxidative stress is lost with age in both sexes.

68 erage reproductive output and wing length in both sexes.

69 ve estrogen-like immunomodulatory affects in both sexes.

70 ribution of the chromosomal abnormalities in both sexes.

71 consistently upregulated by perinatal LPD in both sexes.

72 bling cells in a broad range of organisms in both sexes.

73 y in Drosophila primary olfactory neurons in both sexes.

74 rdination, or grip strength in adult mice of both sexes.

75 ), as well as replicated in meta-analysis of both sexes (1-tailed P = 0.021).

76 Seven pigs of both sexes (10-12 weeks old; 22.2-27.3 kg) were included

77 d that Austria had the largest reduction for both sexes (76.8% males, 76.5% females) from 1980 to 200

78 nction with advanced age or elevated load in both sexes, a significant increase of torsion was more p

79 In both sexes, a single MRI scan at the level of L3 is the

80 al decrease in 5-methylcytosine abundance in both sexes, a transmissible effect that was maintained i

81 64 454 [11%]; females: 44 299 [8%]) and for both sexes, accident was by far the most prevalent of th

82 ct PSC characterized a low-risk phenotype in both sexes (adjusted HR for men, 0.23; P < .001 and adju

83 creased from the 13th rank to the second for both sexes aged 15-19 years from 1990 to 2013.

84 measurements were taken from 108 patients of both sexes, aged 30 to 60 years.

85 s independently associated with mortality in both sexes (all P < 0.05).

86 arm and violent criminality were observed in both sexes, although the IRRs were consistently and sign

87 Similar patterns were seen in both sexes, among black persons, and in the South.

88 countries divided into 21 world regions, in both sexes and 20 age groups, between 1990 and 2015.

89 Among both sexes and across all age groups, mean frequencies o

90 late and sweets" pattern scores decreased in both sexes and across all age groups.

91 o be high among the MUNO and MUO subjects in both sexes and all age groups.

92 rate of detection of nonadvanced adenomas in both sexes and all age groups.

93 the long-term health of cancer survivors of both sexes and all ages at treatment.

94 ort, the exposure of a general population of both sexes and all ages, and the wide range of individua

95 In both sexes and all castes, the largest glomerulus (G1) w

96 ther analgesic reduced F1 fetal GC number in both sexes and altered the tempo of fetal GC development

97 o investigate patterns of DNA methylation in both sexes and among castes of Z. nevadensis.

98 annels, claudins, and selected regulators in both sexes and assessed the physiologic consequences of

99 ve relationship between SES and mortality in both sexes and both settings of care.

100 We found significant differences between both sexes and castes with regard to the relative volume

101 Large, prospective studies including both sexes and circulating PUFAs as dietary biomarkers a

102 erm risk of mortality and ischemic stroke in both sexes and coronary heart disease in women.

103 These findings held true for both sexes and for all bellows whether produced in or ou

104 analyzed alphaII spectrin-deficient mice of both sexes and found that loss of alphaII spectrin cause

105 s in the motor cortex of hSOD1(G93A) mice of both sexes and found that they all exhibit increases in

106 analyzed alphaII spectrin-deficient mice of both sexes and found that, in myelinated axons, alphaII

107 se) had a higher risk of death and stroke in both sexes and incident coronary heart disease in women

108 creening protocols should include infants of both sexes and include follow-up testing algorithms to e

109 ping mice led to behavioral abnormalities in both sexes and MRI-detected brain microstructural altera

110 ndrostenedione (A4), T and estradiol (E2) in both sexes and social classes, during both 'baseline' an

111 gic neurons reverses hyperalgesic priming in both sexes and that a D1/D5 antagonist transiently inhib

112 Major risk factors were biomass smoke for both sexes and tobacco smoke for men.

113 examining the impact of miRNA-based drugs in both sexes and under different disease conditions.

114 Working on the OffOb paradigm in both sexes and using transgenic technology to restore Mc

115 ance of orientation selectivity in human V1 (both sexes) and found that inverting the encoding model

116 ula: see text]and annual breeding success in both sexes, and between maternal inbreeding coefficient

117 expression and activation were determined in both sexes, and chromatin immunoprecipitation was used t

118 unmanipulated (gonad-intact) adult mice from both sexes, and found that in females odorant presentati

119 communicable diseases increased over time in both sexes, and injury was an important cause of death i

120 expression in the liver of Hjv(-/-) mice of both sexes, and led to iron accumulation in the pancreas

121 Tests were done in both sexes, and no sex differences were found.

122 Attractants for both sexes, and particularly females, would minimize the

123 ry neurons of chinchillas and guinea pigs of both sexes, and show how heterogeneous tuning properties

124 xytocin decreases meth demand and seeking in both sexes, and these effects depend on oxytocin signali

125 the transcription of IL-1beta was higher in both sexes, and TNFalpha was elevated in females.

126 00 x 10(-17)) of the total trait variance in both sexes, and we identified a twin heritability of 28%

127 oate to decreased baseline corticosterone in both sexes; and perfluorododecanoate was related to lowe

128 served, however, that Ve patterns in cats of both sexes appear more monopole-like for lower-frequency

129 e cultures derived from mouse spinal cord of both sexes are deficient in supporting both WT and SMN-d

130 from each other or from 1:1, suggesting that both sexes are partially migratory and that migration wa

131 but increased lifetime breeding success for both sexes, arising through increased male longevity and

132 sponses of the bSTC in 10 participants (from both sexes) at 1.5 x 1.5 x 1.5 mm(3) and 1.1 x 1.1 x 1.1

133 e also found that Atoh1 heterozygous mice of both sexes (Atoh1(lacZ/+)) have adult-onset deafness.

134 Atoh1's bHLH domain in vivo Knock-in mice of both sexes bearing a GFP-tagged phospho-dead S193A allel

135 Both sexes became more susceptible to infection as they

136 height with similar patterns for children of both sexes beginning at the initiation of the growth spu

137 elations that indicate shared aetiologies in both sexes between puberty timing and body mass index, f

138 bifactor analysis, to a large set of human (both sexes) brain activation maps (n = 108) encompassing

139 nse to mitral cell action potentials in rat (both sexes) brain slices.

140 ha-mGluR1 and mGluR1-IP3R complexes exist in both sexes but are regulated by E2 only in females.

141 olving conflicts, aggression is expressed by both sexes but often at a higher level in males than in

142 entiates glutamatergic synapses similarly in both sexes, but distinct ER subtypes mediate the presyna

143 duced M2 gene expression in macrophages from both sexes, but more so in macrophages from female mice.

144 on were increased in the highest tertile for both sexes, but not statistically significant when diet-

145 is were associated with persistent wheeze in both sexes, but paternal asthma was associated with pers

146 sed postsynaptic sensitivity to glutamate in both sexes, but that distinct estrogen receptor subtypes

147 with the right MePD larger than the left in both sexes, but with the smaller left MePD actually cont

148 03) of the studies matching the inclusion of both sexes by 50%.

149 in head-fixed, quiet awake GCaMP6 mice from both sexes by using mesoscopic calcium imaging.

150 ats with central 10 degrees retinal lesions (both sexes), by means of real-time PCR for the neuronal

151 mponents of the river gradient and shows how both sexes can exhibit quite different patterns of diver

152 -Sobel = 0.04; Fenland: P-Sobel = 0.0006) in both sexes combined.

153 y in 37 multigenerational human pedigrees of both sexes (consisting of 355 subjects) enriched with le

154 l issue, we studied 87 human participants of both sexes during a stimulus-selective stop-signal task

155 lative ulceration rates (95% CI) declined in both sexes (EAPCs, -3.3% [-4.0% to -2.6%] in men and -3.

156 Healthy subjects of both sexes encoded and retrieved novel objects during pe

157 rs should increase the breeders' survival in both sexes, especially early in life when individuals po

158 Sex biases are eliminated if both sexes evaluate mate availability, but population gr

159 Reproductive traits in both sexes evolved sensitivity to ecological conditions,

160 in sports, with a high dynamic component in both sexes, except for corrected values of the sinotubul

161 Diabetic rats of both sexes exhibit a reduction in cardiac capillary dens

162 the tube, with siblings and/or cagemates of both sexes exhibiting higher cooccupancy behavior than s

163 In this study, we found that aged Tg mice of both sexes expressing human tau proteins harboring a pat

164 Although ryanodine induces priming in both sexes, females are 5 orders of magnitude more sensi

165 e overall decreasing trends in mortality for both sexes, females remain at higher risk of death compa

166 imates for all countries, 20 age groups, and both sexes for 1990 and 2010.

167 imates for all countries, 20 age groups, and both sexes for 1990 and 2010.

168 etween women and men, so we pooled data from both sexes for survival analysis.

169 me breeding success (LBS) was substantial in both sexes: for Fgrm = 0.125, a value resulting from a h

170 The study demonstrates that, in both sexes, fremanezumab inhibited naive high-threshold

171 etherlands, United Kingdom, and Ireland) for both sexes from 1980 to 2009.

172 control of trafficking, we analyzed mice of both sexes from a strain lacking functional ELMOD1 [roun

173 at humans initiate XI by protecting one X in both sexes from inactivation by XIST, the noncoding RNA

174 natal dorsal and lateral lineages in mice of both sexes from stem cells to neurons.

175 In contrast, mortality risk declined for both sexes from the 1960s to the 1990s.

176 uded initial analysis in 1024 adolescents of both sexes from the Canadian Saguenay Youth Study (SYS)

177 dy (SYS) and follow-up in 426 adolescents of both sexes from the IMAGEN Study from 8 European cities

178 ecombination rate was low but significant in both sexes (h(2) = 0.16 and 0.12 in females and males, r

179 Only among those with LBBB, both sexes had better survival with longer QRS duration.

180 We found that chimpanzees of both sexes had significantly higher urinary oxytocin lev

181 ensory-related genes in imaginal bugs, while both sexes had similar expression patterns for most targ

182 fiber layer (RNFL) thinning, despite mice of both sexes harboring tumors of identical volumes and pro

183 h earlier in CD28(-/-) mice and nearly 100% (both sexes) have severe TEC H/P at 4 mo of age.

184 haridin formed blisters of similar volume in both sexes; however, at 72 hours, blisters had only reso

185 r the maintenance of a chronic pain state in both sexes; however, D5 receptors seem to play a critica

186 Transcription of ERVs is derepressed in both sexes in nuage-mutant mice, but whereas males are s

187 ider methods and techniques for inclusion of both sexes in preclinical research and is not intended t

188 Integrating the practice of studying both sexes in preclinical research will, over time, expa

189 as associated with presence of lipid core in both sexes (in women odds ratio, 1.48 [95% confidence in

190 creased significantly in every age group, in both sexes, in every racial/ethnic group, by all educati

191 e absence of OIH in MOR KO mice was found in both sexes, in two KO global mutant lines, and for mecha

192 ort a large genome-wide association study of both sexes including 251,151 individuals for AFB and 343

193 In both sexes, increasing body mass index was associated wi

194 with systolic blood pressure individually in both sexes, individually in one sex only and only when c

195 In short, studying both sexes is a guiding principle in biomedical research

196 and cortical neurons from rodent embryos of both sexes is distributed throughout the somatodendritic

197 ical neurons cultured from embryonic rats of both sexes is induced by neuronal activity via soluble a

198 villagers in communities where dispersal by both sexes is low.

199 the number of trials to reach criterion for both sexes, it increased the duration to complete the ta

200 o provide better diagnosis and treatment for both sexes, it is important to identify factors that und

201 In both sexes, lep-2 mutants fail to cease molting or produ

202 as associated with a large decline in AUD in both sexes (men: hazard ratio=0.56, 95% CI=0.52-0.64; wo

203 In both sexes, methamphetamine seeking in the relapse tests

204 transcriptional activation in germ cells of both sexes much earlier than the SD stage, however, no s

205 We used intracellular recordings in rat (both sexes) neocortical brain slices to assess the ionic

206 tabolic effects in male mice fed the HFD and both sexes of mice fed a chow diet.

207 icular myocytes (ARVMs), and myofibrils from both sexes of rats and observed functional sex differenc

208 aded areas of Japan, the pheromone attracted both sexes of the beetle.

209 Both sexes of the eye-spotted bud moth, Spilonota ocella

210 Whether and how neurons that are present in both sexes of the same species can differentiate in a se

211 ors, but despite similar hyper-locomotion in both sexes, only male Casp3(-/-) mice exhibited social i

212 Experiments were conducted either in both sexes or in females.

213 sed, whereas length of stay has decreased in both sexes over the past several years.

214 In both sexes, patients' age and serum creatinine were asso

215 : 27 to 53 years) with similar prevalence in both sexes; pediatric cases (</=16 years of age) account

216 hizophrenia patients and healthy controls of both sexes performed a modified double-step task.

217 to the courting male, despite evidence that both sexes produce virtually indistinguishable vocalizat

218 reliable marker of ChCs and Cdh6-CreER mice (both sexes) provide genetic access to hippocampal ChCs (

219 For both sexes, quadriceps force was equally reduced after t

220 D concentrations at different time points in both sexes (r = 0.346-0.560, P < 0.001), with stronger c

221 ere associated with declines in IPD rates in both sexes, rates of IPD after PCV13 were still signific

222 For both sexes, readmission risk was highest on days 2 to 4

223 In this species, both sexes reduce their feeding rate in the presence of

224 ion decreased risk of high blood pressure in both sexes (relative risk, 0.83; 95% confidence interval

225 ment and function of the regulatory cells in both sexes requires the basic-helix-loop-helix (bHLH) tr

226 erkats (Suricata suricatta), subordinates of both sexes respond to experimentally induced increases i

227 Here we studied how human brains of both sexes respond to signals under conditions of reduci

228 issected from embryonic and neonatal mice of both sexes respond to the application of glutamate with

229 In vivo imaging of intact embryos of both sexes revealed that the formation of ectopic filopo

230 In both sexes, Scandinavia showed higher rates but earlier

231 In both sexes, self-harm was associated with younger age, w

232 In both sexes, serum PFOS concentrations were inversely ass

233 Both sexes show a 50% reduction of mRNA levels of the ge

234 Stress-sensitive BDNF Val66Met mice of both sexes show a pre-stressed translational phenotype i

235 pain and inflammatory pain states, although both sexes show identical morphologic activation of micr

236 d behavioral studies performed on animals of both sexes showed that blocking Abeta function, by using

237 We then present fMRI data from both sexes, showing that the amygdala tracks these conse

238 In reports that do include both sexes, significant sexual dimorphisms have been dem

239 ions of long-lived mammals, particularly for both sexes simultaneously.

240 cuits regulating parental care are shared by both sexes, some of the fundamental components comprisin

241 ly or primarily expressed in the antennae of both sexes, suggesting their putative role in chemorecep

242 he greater survival in mating individuals of both sexes suggests that variations in individual qualit

243 However, even after 5000 trials, humans of both sexes surprisingly do not change their initial fixa

244 However, the trends were not consistent, for both sexes, systolic BP z-score was stable from 1999, de

245 at 1- and 10-y follow-ups (all P < 0.001 in both sexes) than the control group did.

246 female rats, we identified subpopulations of both sexes that exhibited high (HF) or low (LF) levels o

247 Australia, a country with HPV vaccination of both sexes that is transitioning to 5-yearly HPV-based s

248 We used a preterm fetal sheep model using both sexes that reproduces the spectrum of human cerebra

249 in mechanical and cold allodynia in rats of both sexes that were maintained on a high-fat diet (HFD)

250 We confirmed in an in vitro mouse model (in both sexes) that the frequency of interictal bursts incr

251 ic methods, and using both rats and mice (of both sexes), that corticotrigeminal axons densely innerv

252 We now demonstrate, using mice of both sexes, that horizontal cells do not participate in

253 We found, in acute rat OB slices from both sexes, that inhibitory synchrony is evident in the

254 In both sexes, the association of airflow obstruction with

255 In both sexes, the magnitudes of the associations decreased

256 In both sexes, the protective effect of marriage was signif

257 anthropometric and lifestyle factors.Within both sexes, there are moderate associations between vita

258 Across both sexes, there was a moderately strong positive corre

259 For both sexes, there was a similar timing of peak daily ris

260 community of each tissue of the HPG axis in both sexes, thereby significantly expanding our mechanis

261 Resident individuals of both sexes therefore had higher breeding success than mi

262 For both sexes, these approaches involve an invasive procedu

263 iated with a higher muscle-strength score in both sexes throughout follow-up.

264 ntly of these differences, cardiac CT led in both sexes to a fast final diagnosis when compared with

265 vention in larval Drosophila melanogaster of both sexes to address localization and function of L-typ

266 expressing cells in the whole sheep brain of both sexes to search for an indicator of structural plas

267 We used mice of both sexes to show that impaired Tcf4 function results i

268 estion in young, healthy human participants (both sexes) using concurrent EEG-fMRI and a sustained se

269 yawara community (Kibale, Uganda), adults of both sexes varied widely in their PPC frequency (from <1

270 eakest independent predictor of symptoms for both sexes was history of prior concussions.

271 Here, using rats of both sexes, we applied a modified microinjection method

272 Here, using mice of both sexes, we examined the role of local versus general

273 phrase dissimilarity and genetic distance of both sexes, we found significant results for males but n

274 *) ) and conditional dystroglycan mutants of both sexes, we show that dystroglycan is critical for th

275 For both sexes, we show that pair bonding up-regulates mRNA

276 Here, in mice of both sexes, we show that the binocular matching process

277 Using calcium imaging in awake mice of both sexes, we show that the spatial frequency preferenc

278 Among the most dramatic changes in both sexes were a decrease in concentrations of taurine

279 ic damage, twenty-four healthy volunteers of both sexes were divided into 2 groups.

280 such differences were amplified when mice of both sexes were exposed to STZ-HFD.

281 Marmosets of both sexes were included in this study.

282 ng, sample size estimation, and inclusion of both sexes were not associated with increased citations

283 Adult zebrafish of both sexes were subjected to intravitreal injections of

284 eadmission was similar in women and men, and both sexes were susceptible to a wide range of causes fo

285 In this study, mice of both sexes were used.SIGNIFICANCE STATEMENT To understan

286 (loxP/loxP);Camk2a-Cre(+) (Ctcf CKO) mice of both sexes were viable and exhibited profound deficits i

287 puberty onset and normal adult fecundity in both sexes when leptin signaling is absent in all other

288 hatching, goes through an all-male stage for both sexes (which represents a rare case of "undifferent

289 , we uncover new targets of investigation in both sexes, which could potentially change our understan

290 ld be also detected in antennae and palpi of both sexes, while CjapOBP2, besides male tarsi, is also

291 e to a high-salt diet exacerbated disease in both sexes, while in SJL/JCrHsd mice, it did so only in

292 in cultured hippocampal neurons from rats of both sexes with advanced motion analyses to demonstrate

293 CRT-D was associated with better survival in both sexes with LBBB and QRS >/=130 ms, whereas there wa

294 as associated with a lower mortality risk in both sexes with LBBB, although more pronounced among wom

295 in these lineages resulted in more cells in both sexes with males still carrying more cells than fem

296 GRACE risk scores increased over time for both sexes with the inclusion of older patients with mor

297 with reduced BMI and percentage body fat for both sexes, with a graded pattern apparent across the se

298 rates of STDR were in decreasing trends for both sexes, with a mean of 2.75% for women and 2.87% for

299 Concentric RV remodeling was present in both sexes, with RV mass/volume ratio being positively c

300 for women) and during STI consultations (for both sexes), would substantially reduce HPV incidence an