ライフサイエンスコーパス: bound form

1 -Ras is not as signaling-competent as its PM-bound form.

2 ibosylation factor (ARF5) in its active, GTP-bound form.

3 s the reaction product, Chlide, in an enzyme-bound form.

4 s and sometimes sampling the fully open, CD4-bound form.

5 +/- 3 muM and 2.7 +/- 0.1 muM in the calcium-bound form.

6 molecules only upon conversion to its Ca(2+)-bound form.

7 sociation constant of 2-5 muM in the calcium-bound form.

8 ecture of GluN2A LBD compared to the agonist-bound form.

9 rystal structure of human PI4KIIalpha in ADP-bound form.

10 ulate conformations typical of the substrate-bound form.

11 y to exist that, in part, resemble the final bound form.

12 ly clips H3 in its free as well as chromatin-bound form.

13 , 2BC, and 2BC3AB polyproteins in a membrane-bound form.

14 ctivity and remains always in its active GTP-bound form.

15 but was autophagy-independent for a membrane-bound form.

16 zymatic release or restrict it to a membrane-bound form.

17 of cofactor D, specifically when in the GDP-bound form.

18 as accessible when TG2 was in a cell surface-bound form.

19 ate-free form to a pi helix in the substrate-bound form.

20 ormation similar to the gapped DNA-substrate-bound form.

21 cent penicillin, Bocillin-FL, in free or PBP-bound form.

22 o the FANCD2:FANCI heterodimer in only a DNA-bound form.

23 t is more similar to the GDP than to the GTP-bound form.

24 rotein moiety, as compared to the nucleotide-bound form.

25 phenolic acids in cereals in either free or bound form.

26 inactive" GDP-bound form to the "active" GTP-bound form.

27 d is more active than the alkaline hydroxide-bound form.

28 as shown to activate Cdc42 to its active GTP-bound form.

29 the crystal structure of RasS17N in the GDP-bound form.

30 ns from the MAM(wt) molecule in the receptor-bound form.

31 nt surrounding the labeled side chain of the bound form.

32 from mouse right atrium was in the prodomain-bound form.

33 jority of phenolic acids were present in the bound form.

34 R lacking metal, but are buried in the metal-bound form.

35 to the outward-facing state in a KCl- or HCl-bound form.

36 s monomeric cytosolic or oligomeric membrane-bound form.

37 llosteric site that remains in the substrate-bound form.

38 ssumed that free-form Lpp is associated with bound-form.

39 splicing factor/splicing factor 2 (ASF/SF2)-bound forms.

40 stinguished by its glass adsorbed versus DNA-bound forms.

41 84 intestinal cells in both the apo and iron-bound forms.

42 in the apo and S-adenosyl-L-methionine (SAM)-bound forms.

43 ocator, in both membrane-associated and PcrH-bound forms.

44 ng between inactive GDP-bound and active GTP-bound forms.

45 mations in succinyl-CoA-bound and acetyl-CoA-bound forms.

46 BR2 in the apo, agonist-bound and antagonist-bound forms.

47 ary of ~2,000 binding surface types from the bound forms.

48 ained for the protein in the apo- and Ca(2+)-bound forms.

49 re known to occur in free and glycosidically bound forms.

50 pha-Syn exists in both solution and membrane-bound forms.

51 ated the total phenol pools in both free and bound forms.

52 es as well as between cytosolic and membrane bound forms.

53 ellular sensor domain in both apo and ligand-bound forms.

54 ed RhoA relative to either GDP- or GTPgammaS-bound forms.

55 e structure of XynC in its native and ligand-bound forms.

56 nt crystal structures of AgeI in apo and DNA-bound forms.

57 full-length hexameric Mtb Mpa in apo and ADP-bound forms.

58 pneumoniae (SpNic) in unliganded and ligand-bound forms.

59 white lysozyme (HEL) in unbound and antigen-bound forms.

60 argely as a result of dissolution of surface-bound forms.

61 ions of the tandem domains in different cAMP-bound forms.

62 n NEK1 in its apo- and ATP-mimetic inhibitor bound forms.

63 -products exist in the soluble and insoluble-bound forms.

64 res and dynamics of their free and inhibitor-bound forms.

65 rhodopsin, accelerating the decay of ligand-bound forms.

66 spective (iii) calcium-free and (iv) calcium-bound forms.

67 tes RHEB shuttling between GDP-bound and GTP-bound forms.

68 ermined, both as free proteins and in glycan-bound forms.

69 rom Escherichia coli in apo, GDP-, and ppGpp-bound forms.

70 As, activate PKR in TRAP-free and TRAP/l-Trp-bound forms.

71 cherichia coli RppH (EcRppH) in apo- and RNA-bound forms.

72 ct RIalpha (91-379) in its apo, cAMP2, and C-bound forms.

73 of Roquin paralog RC3H2 in both apo- and RNA-bound forms.

74 of an Fe2+ cofactor and in its apo (non-Fe2+-bound) form.

75 n its apo (i.e., no l-tryptophan corepressor-bound) form.

76 effector of Rab26 and binds Rab26 in its GTP-bound form, albeit only with low affinity.

77 wer levels, we expressed CD40L in a membrane-bound form, along with SIV antigens, in a nucleic acid (

78 s, (i) as a Ca(2+)-binding protein in Zn(2+)-bound form and (ii) as a protease in Zn(2+)-free form, c

79 f differentiating between the neutral ligand bound form and adsorbed ion pairs is discussed.

80 urface molecule that is found in both a cell-bound form and cell-free form in the host during an infe

81 EF-G binds to the ribosome in a GTP-bound form and subsequently catalyzes GTP hydrolysis.

82 tein alpha subunit in its apo and nucleotide-bound forms and characterized their dynamical features a

83 nd VanXYG in apo and transition state analog-bound forms and of VanXYC in complex with the D-Ala-D-Al

84 rystal structure of RovA in the free and DNA-bound forms and provide evidence that thermo-induced los

85 HAR) in the native, ascorbate-bound, and GSH-bound forms and refined their resolutions to 1.9, 1.7, a

86 occur in the free, esterified and insoluble-bound forms and serve as natural antioxidants by prevent

87 sured free anti-oxLDL (unbound and partially bound forms) and Assay B measured total anti-oxLDL.

88 petitive antagonist-bound states, an agonist-bound form, and a state bound with agonists and the allo

89 that Rabs are soluble in their inactive GDP-bound form, and only upon activation and conversion to t

90 G11.2) that recognizes, in both free and HDL-bound forms, apoA-I harboring a 3-nitrotyrosine at posit

91 Rabs in their GDP-bound form are kept soluble in the cytoplasm by the GDP

92 he Galpha subdomain, whereas the apo and GDP-bound forms are considerably more open and dynamic.

93 rganic and iron-bound P species into calcium-bound forms, as a possible consequence of the partial mi

94 domain of CD23 in its Ca(2+)-free and Ca(2+)-bound forms, as well as the crystal structure of the Ca(

95 delta2 interacts with omega2 and, in the ATP-bound form, binds to nonspecific DNA (nsDNA), forming sm

96 in plants and plant foods not only in their bound form but also as free acids that can be extracted

97 ) displayed similar patterns in the free and bound forms, but, nonetheless, showed interesting differ

98 hich was primarily presented in its membrane-bound form by follicular dendritic cells.

99 Heme-free mPGES2 was converted to the heme-bound form by mixing it with pig liver extract, indicati

100 o it is possible to gain insight into ligand-bound forms by considering conformational variation in a

101 glycosylated HIV gp120 in unliganded and CD4-bound forms by using small-angle X-ray scattering to vis

102 remains unclear whether any of these ligand-bound forms can be observed by ESI-MS.

103 can be toxic when it occurs in a non-protein-bound form; cells maintain a fine balance between heme s

104 structures of TgAMA4 in the apo and TgRON2L1-bound forms complemented with alanine scanning mutagenes

105 phenolic acids increased (30%) and insoluble-bound forms decreased (17%), suggesting partial conversi

106 es of LarE in ligand-free and several ligand-bound forms, demonstrating that LarE is a member of the

107 rmations for E108 residue in the ATP and ADP bound forms, E108Q adapts the same conformation irrespec

108 xo-1(2H)-pyri midinepropanoic acid (UBP-282)-bound form exhibiting the widest range of cleft closure

109 he orientation of the enzyme in its membrane-bound form experimentally.

110 tures of folding competent substrates in the bound form have not been well characterized.

111 x properties of both the Fe(III)- and Fe(II)-bound forms have been characterized using the UV-visible

112 rpR, in their holo (l-tryptophan corepressor-bound) form have been characterized using (15)N nuclear

113 ed neurotrophic factors and, unlike membrane-bound forms, have a unique ability to diffuse and adhere

114 ved for an activated transition-state analog-bound form II ribulose-1,5-bisphosphate carboxylase/oxyg

115 release of the free drug from the covalently bound form in a desired fashion.

116 pyrrole pigment usually found as the protein-bound form in cyanobacteria and red algae.

117 ween an inactive soluble and active membrane-bound form in response to changes in membrane lipid comp

118 at the unbound form is highly similar to the bound form in terms of both the beta-strand framework th

119 propose that conversion of ARF6 into the GDP-bound form in the apical domain of hair cells is essenti

120 s been investigated to assess the role of Fe-bound forms in NIF-specific Fe-S cluster biogenesis.

121 stacking structure of these molecules in the bounded form in water medium.

122 lecules in the binding site of the substrate-bound form, in agreement with the number of water molecu

123 fluorescence was also observed in its actin-bound form, indicating that the dystrophin N-ABD binds t

124 not PsV expressing a cytoplasmic or membrane-bound form, induced circulating and intravaginal-tissue-

125 within the ER both in secretory and membrane-bound forms, inducing their degradation following retrot

126 Rab11, in its GTP-bound form, interacts with Rabin8 and kinetically stimul

127 229 +/- 37 mM, and binding to the glutamate-bound form is associated with a K(m) = 76 +/- 40 mM.

128 s suggest that conversion of ARF6 to its GDP-bound form is necessary for final stabilization of the h

129 cond phase, the NC domain binds RNA, and the bound form is stabilized by intermolecular interactions

130 mponent in both membrane-bound and chaperone-bound forms is a key step for the eventual development o

131 However, only the membrane-bound form localized to the developing septum and restor

132 gh it is known that the carboxyl-terminus of bound-form Lpp is located in the periplasm, the precise

133 ter membrane and is surface-exposed, whereas bound-form Lpp resides in the periplasm.

134 ), respectively), suggesting that the Ca(2+)-bound form may be physiologically relevant for stressed

135 RAS is persistently frozen in its active GTP-bound form may not be accurate.

136 d conformation, in contrast to the inositide-bound form obtained previously in a closed conformation.

137 a and in the catalytically inactive/membrane-bound form, obtained with the application of protein-pro

138 of the protein from the unbound form to the bound form occurs before or after encountering the ligan

139 for an allosterically inhibited and agonist-bound form of a functional NMDA receptor; however, other

140 e the coordination of copper to the membrane-bound form of alpha-syn.

141 o70, and Sec5 bind preferentially to the GTP-bound form of Arl13b, consistent with the exocyst being

142 nd of ppGpp to BipA, indicate that the ppGpp-bound form of BipA adopts the structure of the GDP form.

143 g subunit-subunit interface in the substrate-bound form of BsPFK.

144 The Ca(2+)-bound form of CaBP7 NTD is monomeric and exhibits an ope

145 e low frequency coherence spectrum of the CO-bound form of Ch-CooA shows a strong vibration at ~230 c

146 Protein-specific DNA binding to the CO-bound form of Ch-CooA was also investigated, and althoug

147 quired the specific interaction of the Cu(+)-bound form of CopA with apo-CusF for subsequent metal tr

148 n agreement with previous work, the membrane bound form of Cripto-1 potentiated signaling, revealing

149 gene regulatory region occupancy by the DNA-bound form of cyclin D1 and induction of CIN gene expres

150 -wide ChIP sequencing and found that the DNA-bound form of cyclin D1 occupied the regulatory region o

151 ridging sulfides in the [4Fe-4S](2+) cluster-bound form of FNR facilitated identification of resonant

152 rum of the O(2)-exposed [2Fe-2S](2+) cluster-bound form of FNR.

153 he N-acylation, but does not require the GTP-bound form of Galpha(t1).

154 that VVC-resistant viruses use the inhibitor-bound form of Galphai-coupled CCR5 more efficiently than

155 nd this interaction is stronger with the GDP-bound form of Galphao.

156 A metabolically biotinylated, membrane-bound form of Gaussia luciferase was synthesized, termed

157 disordered switch II in the uncomplexed GTP-bound form of H-Ras.

158 "off" and "on" allosteric states of the GTP-bound form of H-Ras.

159 Only the ATP-bound form of Hsp90 interacts with disordered CTA1, and

160 ecruitment of the cochaperone p23 to the ATP-bound form of Hsp90, forming an FKBP51-Hsp90-p23 superch

161 ciation constant for dissociation of the ATP-bound form of huM3AMD from actin is greatly increased by

162 sticity of the dimeric state of the [2Fe-2S] bound form of human GRX5 (holo hGRX5) is the crucial fac

163 The GTP-bound form of IF2 accelerates subunit joining, whereas I

164 cal inhibitors preferentially target the DNA-bound form of integrase as compared with the free protei

165 tein-Barr virus (EBV) increases the membrane-bound form of LC3 (LC3-II) and LC3-containing punctate s

166 ion of dihydrolipoamide, the reduced protein-bound form of lipoic acid.

167 )C}(7)Li dipolar recoupling experiments, the bound form of lithium in the active site of wild-type E.

168 ollectively, these results show that the ATP-bound form of MRN is the critical conformation for ATM a

169 We now report that a membrane-bound form of murine CD80 similarly reduces PDL1-PD1-med

170 the central beta-sheet similarly to the ATP-bound form of Ncd.

171 The bound form of Neu5Gc is bioavailable, undergoing metabol

172 We also find that the serum protein-bound form of NY is photoacoustically well-behaved and s

173 ions to refine the structure of the membrane-bound form of Pf1 coat protein in explicit lipid bilayer

174 we report the crystal structure of the lipid-bound form of PgpB.

175 de exchange factor (GEF) to generate the GTP-bound form of Rab10, but this GEF has not hitherto been

176 and thereby leads to an increase in the GTP-bound form of Rab10, which in turn triggers movement of

177 EPI64B almost completely abolished the GTP-bound form of Rab27B, without affecting GTP-Rab3D.

178 -bound RAB7, but not a dominant-negative GDP-bound form of RAB7, promoting rapid transfer and lysosom

179 ike molecules that bind to a site on the GDP-bound form of Ral.

180 Gef3p interacts physically with the GTP-bound form of Rho3p.

181 ognate eukaryotic effectors, as only the GTP-bound form of RhoA family members stimulates enzymatic a

182 y of Ssq1 and is most pronounced for the ADP-bound form of Ssq1, which interacts with Isu1 most tight

183 IL-33, signaling through ST2L (the membrane-bound form of ST2), promotes transplant survival is uncl

184 MD simulations of the Ca(2+)-bound form of Syt1 revealed that Syt1 conformational fle

185 es to generate a molecular model of a Ca(2+)-bound form of Syt1.

186 ciated with characterization of the membrane-bound form of talin have prevented us from understanding

187 The chlorowillardiine- and nitrowillardiine-bound form of the agonist-binding domain probes a narrow

188 as 1B6 that recognize the more abundant GAG-bound form of the chemokine may not be the optimal strat

189 ists in the characterization of the receptor-bound form of the chemokine.

190 d conformation and propose that the membrane-bound form of the cytodomain represents its native confo

191 n (SH3) client protein interact with the ADP-bound form of the DnaK chaperone.

192 ction occurs whereby mutations shift the ADP-bound form of the enzyme towards an ATP-like state in a

193 otably, the methyl-thiazole prefers the NADH-bound form of the enzyme with a Kd of ~13.7 nM, as again

194 with a Kd of ~13.7 nM, as against the NAD(+)-bound form of the enzyme.

195 The ATP-bound form of the Escherichia coli DnaA protein binds 'D

196 The ATP-bound form of the Escherichia coli DnaA replication init

197 Using the membrane-bound form of the fd coat protein as a model membrane pr

198 fection of human tumor cells with a membrane-bound form of the human costimulatory molecule CD80 prev

199 iptional expression switch from the membrane-bound form of the immunoglobulin heavy chain to its secr

200 A crystal structure of the ADP-bound form of the KIF14 motor domain reveals a dramatica

201 Expression of a membrane-bound form of the protein resulted in a marked and speci

202 The LPS-bound form of the protein was substantially more resista

203 osure states relative to the iodowillardiine bound form of the protein, with the antagonist (alphaS)-

204 he tetraphenylphosphonium (TPP(+)) substrate-bound form of the protein.

205 resistance describe an ability to use a drug-bound form of the receptor, leading to reduction in maxi

206 r modeling docking studies using the agonist-bound form of the X-ray crystal structure of the acetylc

207 nism involves signaling between the membrane-bound form of TNF-alpha on activated CD8(+) T cells and

208 he cleaved form of alphaKlotho, the membrane-bound form of which is an FGF23 coreceptor, serves as a

209 a are consistent with a model in which a DNA-bound form of Yap8 acts directly as an As(III) sensor.

210 ree Fe(II) from both the Fe(II)- and Fe(III)-bound forms of (Nif)IscA.

211 rved under acidic conditions, whereas sulfur-bound forms of Ag dominated in neutral to alkaline soils

212 diine > chlorowillardiine > nitrowillardiine-bound forms of agonist-binding domain.

213 he crystal structures of apo- and ADP/Mg(2+)-bound forms of Aquifex aeolicus LpxK to a resolution of

214 free, esterified, glycosylated and insoluble-bound forms of araticum pulp, peel and seed were for the

215 ent in the free, soluble ester and insoluble-bound forms of blackberry, black raspberry and blueberry

216 MAP3K protein MRK directly binds to the GTP-bound forms of both RhoA and RhoC in vitro.

217 nalysis demonstrates that the apo and Mg(2+)-bound forms of CBD12 are highly flexible, whereas Ca(2+)

218 rence spectra of the ferric, ferrous, and CO-bound forms of Ch-CooA in order to compare the protein-i

219 des at ~48 cm(-1) in both the ferrous and CO-bound forms of Ch-CooA is consistent with coupling of th

220 Crystal structures of the apo and PEP-bound forms of D12A BsPFK have been determined (Protein

221 h closely resemble the autoinhibited and DNA bound forms of Ets-1.

222 We determined structures of ATP-free and -bound forms of human TRPV4-ARD and compared them with av

223 h to spatially map NADH in both the free and bound forms of live undifferentiated and differentiated

224 and challenges models in which the free and bound forms of Lpp are assumed to be associated with eac

225 In this work, we show that the free and bound forms of Lpp are not largely associated with each

226 The purified and membrane-bound forms of MBH both preferentially evolved H2 with t

227 the average structures of the apo and Hg(II)-bound forms of MerR in aqueous solution are examined usi

228 lyzing purified preparations of apo- and ion-bound forms of NCX_Mj-WT and its mutant, NCX_Mj-5L6-8.

229 MR solution structures of reduced and Hg(2+)-bound forms of NmerA are presented that allow definition

230 le, atomistic simulations of the unbound and bound forms of NorM in a phospholipid lipid bilayer allo

231 idized and the S-adenosyl-l-methionine (SAM) bound forms of pyruvate formate-lyase activating enzyme

232 ort is likely a gradient of the GDP- and GTP-bound forms of Ran, a small GTPase.

233 striking exception to the rule that only GTP-bound forms of Ras-superfamily GTPases have active confo

234 y to characterize the ligand-free and ligand-bound forms of SAM-II riboswitch.

235 solution structures of the free and arginine-bound forms of stem loop 4 of 7SK (7SK-SL4).

236 MD) simulations of Ca(2+)-unbound and Ca(2+)-bound forms of Syt1.

237 Although the structures of free and bound forms of TAR are well characterized, the conformat

238 00-ns trajectories of the free and substrate-bound forms of TEM-1 (with benzylpenicillin) and PSE-4 (

239 The biliverdin-bound forms of the BphPs have the additional property of

240 n microscopy reconstructions of free and DNA-bound forms of the Cascade/I-C surveillance complex reve

241 e report here structures of the free and DNA-bound forms of the DBD of NtrC4 (4DBD) from Aquifex aeol

242 the nucleotide binds to the free and singly bound forms of the enzyme with nearly equal affinity ove

243 In all of the bound forms of the enzyme, however, the proposed catalyt

244 arrangement in the apo form and GDP- and GTP-bound forms of the factor, raising the question of how S

245 and remarkably different for GDP- and GppNHp-bound forms of the G domain, indicating that the GTP-bin

246 uce mRNAs encoding the secreted and membrane-bound forms of the immunoglobulin (Ig) heavy chain.

247 vey common foods for free and glycosidically bound forms of the nonhuman sialic acid N-glycolylneuram

248 free forms of homologs than to the substrate-bound forms of the other phosphagen kinases.

249 ive NMR analysis of the apo, cGMP-, and cAMP-bound forms of the PKG cyclic nucleotide-binding domain

250 the labeled sites between the apo and ligand-bound forms of the proteins, which are easily distinguis

251 The cycling between GDP- and GTP- bound forms of the Ras protein is partly regulated by th

252 ws signal rejection of diffusing relative to bound forms of the same PS-FP, rsFastLime.

253 ch FKBP51 binds to both the apo- and hormone-bound forms of the steroid receptor to modulate its affi

254 pond differently to the soluble and membrane-bound forms of their respective ligands.

255 esent crystal structures of the free and CMP-bound forms of WaaA from Aquifex aeolicus, an ancient Gr

256 r previously reported data for the glutamate-bound forms of wild type and T686S mutant proteins, show

257 y solved ligand-free and double-stranded-RNA-bound forms of ZEBOV VP35 IID structures, our current st

258 The 'bound' form of the protein is tethered to the outer memb

259 Omicron-(gamma-thio)triphosphate (GTPgammaS)-bound) form of Tr*, we found that Tr* activated PDE at a

260 or both active (GTP-bound) and inactive (GDP-bound) forms of Galpha subunits.

261 by the interconversion between GTP- and GDP-bound forms partly regulated by the binding of the guani

262 ermination of protein-free and total (free + bound forms) positron emission tomography (PET) radiolig

263 5M-thrombin), were compared to the substrate-bound form (PPACK-thrombin).

264 uggest that the mobility of the full agonist-bound form primes the GPCR to couple to IBPs.

265 lexibility, when three Ca2+ or two Mg2+ were bound forming probably the structural basis for the modi

266 d form promoted by GEFs and its inactive GDP-bound form promoted by GAPs to affect the control of var

267 Ras GTPase cycles between its active GTP-bound form promoted by GEFs and its inactive GDP-bound f

268 In their active GTP-bound form, Rab proteins interact with proteins termed e

269 excited kynurenines in both free and protein-bound forms rapidly oxidized ASC, and such oxidation occ

270 e ligand "slips" between bidentate and arene-bound forms: rather than dissociation, the cobalt slides

271 RecA, in the ATP . Mg(2+)-bound form (RecA . ATP), can nucleate and form filament

272 free or weakly bound molecule and a tightly bound form released by acid hydrolysis, at concentration

273 A comparison of the Hb-free and Hb-bound forms reveals that Hb binding alters the positioni

274 In its GTP-bound form, Ryh1, an evolutionarily conserved Rab GTPase

275 of ligand-free CouR and its p-coumaroyl-CoA-bound form showed no significant conformational differen

276 s of the IL-2 superkine in free and receptor-bound forms showed that the evolved mutations are princi

277 an open conformation, whereas the nucleotide-bound form shows a half-closed conformation, in contrast

278 of E. coli ACPS in unliganded and holo-ACPP-bound forms solved by X-ray crystallography to 2.05and 4

279 nsition of Cas9 from its apo form to the RNA-bound form, suggesting a mechanism for RNA recruitment i

280 concentrations of beta-damascenone, and some bound-form terpenoids.

281 ures coalesce into a single, more stable udp-bound form that features a three-helix bundle containing

282 tively unfolded and monomeric and a membrane-bound form that is composed of an alpha-helical multimer

283 of transcription factor signaling via a DNA-bound form, the induction of chromosomal instability, en

284 nly binds MreB in the guanosine triphosphate-bound form, the motility complexes are assembled at the

285 lanine is not specially favored in the lipid-bound form; the chimeric construct with polyalanine prod

286 e of 509+/-51 s(-1) , whereas in the glucose-bound form these exchange processes were quenched.

287 droxymethyl of Thr(772) rotates to stabilize bound Form(+) through water molecules, and 3) the rotame

288 amily that is highly expressed in a membrane-bound form throughout the respiratory tract.

289 o the [4Fe-4S] cluster, and exposure of this bound form to O2 results in cluster conversion to the [2

290 which convert them from their "inactive" GDP-bound form to the "active" GTP-bound form.

291 thesis initiation factor 2 (eIF2) from a GDP-bound form to the active eIF2-GTP complex.

292 We find that cryoreduction at 77 K of the O2-bound form, trapped in the conformation of the parent ox

293 creased fluctuations are seen in the camphor-bound form using all three techniques, dominated by chan

294 undetectable in its parent form, whereas the bound form was readily quantified, employing the modifie

295 atural peptides in their free and HLA-B*0801-bound forms, we characterized the mode of action of ERAP

296 ry exchanges between apoenzyme- and coenzyme-bound forms were observed.

297 It exists in two distinct forms: a 'bound-form', which is covalently bound to the cell's pep

298 ctional states, the DNA-bound and the ligand-bound form, which are allosterically regulated.

299 s of HiNmlR in both the DNA-free and two DNA-bound forms, which suggest that HiNmlR enhances target g

300 diate states characterized by a Tyr(75)-iron-bound form with open conformation of loop L1.