ライフサイエンスコーパス: bowl

1 evels comparable to those of the 1930s 'dust bowl'.

2 encoding a MAPK), 14-3-3epsilon, and bowel (bowl).

3 ing the electron-rich cavity of the aromatic bowl.

4 ytic priming; K95 lies deeper in the chalice bowl.

5 uctures by destabilizing the nuclear protein Bowl.

6 l density to appear both above and below the bowl.

7 in which the Cs+ cation resides in the calix bowl.

8 ptor-binding site sequestered in the chalice bowl.

9 closed assembly that forms the bottom of the bowl.

10 the zinc-finger proteins Drumstick (Drm) and Bowl.

11 regating Lines away from nuclearly localized Bowl.

12 nker caps a hydrophobic area adjacent to the bowl.

13 ntain as keeping a marble near the base of a bowl.

14 attached to the interior carbon atom of the bowl.

15 ts the conformer distribution toward perfect bowls.

16 g to the formation of ellipsoids, discs, and bowls.

17 s(+) ions sandwiched between two corannulene bowls.

18 ndpaper) encountered before they reached the bowls.

19 ivalent to smoking 365 joints or filled pipe bowls.

20 cting in synergy with CsF, yielded molecular bowl 1syn in a moderate 30% yield.

21 ne 7 has been investigated to give molecular bowl 1syn in a stereoselective fashion.

22 ble (4.5:1) ratio, in favor of the molecular bowl 1syn.

23 )day(-1) through daily consumption of half a bowl (65g) of breakfast cereal and four slices of toaste

24 Lines binds directly to Bowl and decreases Bowl abundance.

25 One site, together with the Ca(2+) bowl, accounts for all physiological regulation of BK ch

26 Here, we show that Bowl accumulates in the PE from early stages of wing dev

27 ly, we show that Drm and Lines also regulate Bowl accumulation and consequent patterning in the epith

28 ting drm expression, while Wingless inhibits Bowl accumulation by repressing drm expression anterior

29 Conversely, Drm allows Bowl accumulation in drm-expressing cells by inhibiting

30 Together, lines and bowl act as a binary switch to generate a stable Notch s

31 or tennis facilities, indoor ice arenas, and bowling alleys were higher than at traditional fitness c

32 groups to the corannulene core flattens the bowl and affects the solid-state packing.

33 otein-protein interactions between Lines and Bowl and between Drm and Lines regulate the steady-state

34 Lines binds directly to Bowl and decreases Bowl abundance.

35 omains engage ESCRT-III substrates above the bowl and help transfer them into the bowl to be pumped t

36 Thus, we provide evidence that bowl and lines act as a binary switch to subdivide the w

37 of Hsp31 mutants, we show that although both bowl and linker-loop-shielded residues participate in su

38 r of the slo1 high-affinity sensors (calcium bowl and RCK1 Asp362/Asp367) is required for ethanol to

39 of the recent multiyear drought or the Dust Bowl and the 1950s droughts will become the new climatol

40 open assembly that defines the sides of the bowl and the lower ring forming a closed assembly that f

41 t these theories and explore new hypotheses; Bowles and Choi have developed one such model.

42 property rights (lending further support to Bowles and Choi's original proposal).

43 We have replicated the model of Bowles and Choi, and used the FIO method to identify com

44 The work of Boyd, Richerson, Fehr, Gintis, Bowles and their collaborators has long included the the

45 acellular C terminus, including the 'calcium bowl' and the RCK domain, is not necessary for the calci

46 udes a high-affinity Ca(2+)-binding site (Ca bowl) and contains similar secondary structural elements

47 partic amino acids that is known as the Ca2+ bowl, and is located within the second of the tandem RCK

48 Further, we show that drm, bowl, and lin are required for patterning of the hindgut

49 hat the defect in hindgut elongation in drm, bowl, and lin mutants is due, in large part, to the requ

50 transcriptional regulators, drumstick (drm), bowl, and lines (lin), are required to establish normal

51 The genes drumstick, bowl, and lines (which encode putative transcriptional r

52 signaling molecules regulated by drumstick, bowl, and lines, in particular of the JAK/STAT activator

53 on the symmetry axis above the cavity of the bowl, and the binding of six extended Vta1p monomers cau

54 many tissues, lines acts antagonistically to bowl, and we found that this is true for hub specificati

55 can open with 0, 1, 2, 3, or 4 functional Ca-bowls, and that each subunit with a functional Ca-bowl c

56 Unique structures (bowls, arcades of hooks, cones at the cell ends, two lay

57 Thus, Drm, Lines, and Bowl are components of a molecular regulatory pathway th

58 odd, sob, drm, and bowl are expressed in a segmental pattern in the develop

59 ee Ca(2+) binding sites including the Ca(2+) bowl are mapped onto the structure based on mutagenesis

60 is true for hub specification, establishing bowl as a positively acting factor in the development of

61 ypes, HF-lesioned pigeons consistently chose bowls associated with one of the training stimuli.

62 On test trials, pigeons chose the bowl at the correct location in the room if either the c

63 have revealed the presence of a hydrophobic bowl at the Hsp31 dimer interface and shown that the lin

64 ania, Italy) and preserved in their original bowls at the Naples National Archaeological Museum (Ital

65 e trained to discriminate between two reward bowls based on a stimulus (rough/smooth sandpaper) encou

66 intake was measured by weighing the feeding bowl before and after meals, and breast milk intake was

67 expands into distal and proximal regions in bowl clones.

68 rene adopts a boat conformation in 1-4 and a bowl conformation in 5 and 6.

69 The calculations also revealed that the bowl constriction is necessary for the aromatic arms to

70 , and that each subunit with a functional Ca-bowl contributes a stepwise increase to both the coopera

71 a long-standing history of chewing on toilet bowl deodorizing cakes.

72 ction from which an empirical correlation of bowl depth and inversion barrier that follows a quartic

73 lowed for a study correlating the structure (bowl depth) and the energy of bowl inversion.

74 d to access bond lengths, bond angles, and a bowl depth.

75 ries of corannulene derivatives with varying bowl depths has allowed for a study correlating the stru

76 In this bowl-digging task, rats encounter two equal value learni

77 approaches to the treatment of inflammatory bowl disease and intestinal infections and to new immuni

78 mutations increase the risk for inflammatory bowl disease and the severity of graft-versus-host disea

79 s, pi-pi bonding between convex sides of the bowls dominate, while pi-H bonding between rim and conve

80 or sumanene on Ag(111) that both bowl-up and bowl-down conformations can be stabilized.

81 in the CTL group could win vouchers in prize-bowl drawings, but HIV care behaviors were not incentivi

82 reproduce the anomalous features of the Dust Bowl drought.

83 lead to maize losses equivalent to the Dust Bowl drought.

84 The "Dust Bowl" drought of the 1930s was highly unusual for North

85 anges experienced in utero in America's Dust Bowl during the Great Depression to unusually detailed i

86 s and the most severe drought since the Dust Bowl era of the 1930s, resulting in substantial economic

87 ral regions comparable to those of the "dust bowl" era and inexorable sea level rise.

88 trained to find food hidden in 1 of 4 color bowls (feature cues) located next to a landmark beacon (

89 ta-strand IV to the II-III loop, and a broad bowl from helix A to helix C.

90 ranched pathway downstream of Notch in which Bowl functions to direct hub cell assembly in parallel t

91 tterns; in contrast, the less-tightly linked bowl gene is expressed in a distinctly different pattern

92 The bowl gene is therefore required for the elaboration of p

93 h signaling, which induces expression of the bowl gene, the product of which represses ap.

94 t lists of RNA 3D structures provided by the Bowling Green State University RNA group, R3D Align conn

95 e hypothesis to reconcile these data is that bowl has a role at an earlier stage in tarsal developmen

96 l Ca(2+)-regulatory site, termed the 'Ca(2+) bowl', has been located to the large cytosolic carboxy t

97 the intrinsic properties of redox-active pi-bowls, has been prepared.

98 For surface-adsorbed pi bowls, however, only conformations with the bowl opening

99 turn, Dl signals asymmetrically to stabilize Bowl in adjacent distal cells.

100 This is accomplished both by outcompeting Bowl in binding to Lines and by redistributing Lines to

101 nes protein destabilizes the nuclear protein Bowl in ectodermal structures.

102 Conversely, the activation of bowl in the DP (by removal or inhibition of lines functi

103 Broad inhibition of Bowl in the PE resulted in the replacement of the PE wit

104 ion to positional disorder of the C(40)H(50) bowls in the solid-state structure, has prevented the ac

105 s that catalyse nanowire growth as a 'mixing bowl', in which growth materials are sequentially suppli

106 revealed the preservation of the corannulene bowl inside the prepared rigid matrix, which offers the

107 ten the bowl, thus causing a decrease in the bowl inversion barrier.

108 epening of the bowl, thus an increase in the bowl inversion barrier.

109 d by dynamic NMR analysis, showing a bowl-to-bowl inversion energy (DeltaG()) of 16.7 kcal mol(-1), w

110 A bowl-to-bowl inversion for a C70 fragment in solution was invest

111 the planar transition state for the bowl-to-bowl inversion of (ethyl)corannulene (which accelerates

112 The transition state structure for bowl-to-bowl inversion of 1 is planar (D(2)(h)()) and lies 30.9

113 nted structural phase transition involving a bowl inversion of one-third of the molecules.

114 Catalysis of the bowl-to-bowl inversion processes that pertain to corannulene is

115 the structure (bowl depth) and the energy of bowl inversion.

116 Bowl-inversion barriers around DeltaG(double dagger) = 1

117 We also show that the Ca bowl is an essential element for the Ca(2+)-induced rear

118 s) and, like its close relative Odd-skipped, Bowl is produced in response to Notch signalling at a su

119 Ca(2+), the affinity of Ba(2+) to the Ca(2+) bowl is reduced about fivefold, and coupling of binding

120 One site, termed the Ca(2+) bowl, is embedded within the second RCK domain (RCK2; re

121 Conversely, ectopic bowl leads to a reduction in bric-a-brac2, with a concom

122 The latter guests are bound within the bowl-like cup of the C4P in a ball-and-socket binding mo

123 ed in pericentral hepatocytes resulting in a bowl-like distribution in marked contrast with that of t

124 Lastly, we demonstrate that the as-derived bowl-like mesoporous carbon particles manifest enhanced

125 Bowl-like mesoporous carbon particles with radially orie

126 anisotropic assembly approach to synthesize bowl-like mesoporous polydopamine particles with diamete

127 external structures were revealed, including bowl-like objects decorating the outer membrane, arcades

128 The ATPase domains of Vps4p form a bowl-like structure composed of stacked hexameric rings.

129 determining region (CDR) structures with a "bowl-like" conformation in CDR-H2 that tightly and speci

130 y different from the future permanent, 'dust-bowl-like' megadrought conditions, lasting decades to a

131 The Ca(2+) bowl, located within the second RCK domain, forms an EF-

132 Compared with previous estimates for Ca(2+) bowl-mediated activation by Ca(2+), the affinity of Ba(2

133 ich five consecutive Asp residues of the "Ca-bowl" motif are changed to Asn, reduces (45)Ca(2+)-bindi

134 al of these genes have altered expression in bowl mutant cells.

135 ntation, and thus appear to act redundantly, bowl mutant clones do perturb leg development.

136 Specifically, bowl mutant clones result in a failure of joint formatio

137 However, despite the fact that bowl mutant clones result in fusion of tarsomeres, Bowl

138 We therefore investigated the effects of bowl mutations on the expression of leg 'gap' genes that

139 re trained to find food located in a colored bowl, near a landmark beacon, in a constant room locatio

140 ly important mutations cluster near the Ca2+ bowl, near the "flexible interface" between RCK domains,

141 moved by itself but chose the correct color bowl next to the beacon if they were moved together.

142 (3) a beta-turn, sitting in the middle of a bowl of alpha-helix residues.

143 ace, such as breakfast cereals floating in a bowl of milk or bubbles at the surface of a soft drink,

144 The Dust Bowl of the 1930s was the driest and hottest for agricul

145 assembly of the C38H14-buckybowl, a fragment bowl of the C70 fullerene, has been studied with scannin

146 A bowl of ~100 to 150 g cooked GR (50 g dry weight) can pr

147 pressure differentials, then was poured into bowls open to the OR 2 environment before injection into

148 bowls, however, only conformations with the bowl opening pointing away from the surface have been ob

149 of the molecules are oriented such that the bowl opening points down.

150 Isolated molecules adsorb bowl opening-up with the center C6 ring parallel to the

151 ameworks with the intrinsic properties of pi-bowls opens a new avenue for preparing redox-active mate

152 All subjects (100%) had a so-called bowl or convex shape to the choroid-sclera junction, and

153 ect location in the room if either the color bowl or the beacon was moved by itself but chose the cor

154 ent age in current users) multiplied by pipe-bowls or cigars per day.

155 ect that was either a conceptual match (e.g. bowl) or mismatch (e.g. wood).

156 at was classed as optimistic if it chose the bowl ordinarily associated with the high value reward.

157 Many became grossly enlarged, bowling-pin-shaped cells having up to 80-fold-increased

158 r than what has been reported for the double-bowl polyurethane foam PAS.

159 d onto National Surgical Adjuvant Breast and Bowl Project protocol C-04.

160 Hedgehog promotes Bowl protein accumulation by promoting drm expression, w

161 utant clones result in fusion of tarsomeres, Bowl protein is only found at the t1/tibial and t5/preta

162 While the Sob and Bowl proteins each contain five tandem fingers, the Odd

163 ome-host interactions before and after small bowl radiation injury may eventually allow prediction of

164 h-affinity Ca(2+)-binding site (the "calcium bowl") reduced the Ca(2+) and abolished the Mg(2+) depen

165 al reasons: (a) its sequence similarity with bowl required for Drosophila hindgut development; (b) it

166 ts with a mutation to disrupt a key site (Ca-bowl) required for activation by low concentrations of C

167 parotomy for 2 patients (with necrotic small-bowl resection for 1 of these patients).

168 We find that mutations in bowl result in similar phenotypes to Notch, causing fusi

169 pheral B atom by Al in B(12)(-), which has a bowl shape with a B(9) outer ring and an out-of-plane in

170 mined by the complementary shape between the bowl-shape of the cavity and the shape of the ligand.

171 The stable bowl-shape stomatocyte morphology is ideal for the speci

172 (4-) )](2-) , illustrate a record ability of bowl-shaped and highly charged corannulene to provide al

173 esidue Ser205, contributes to formation of a bowl-shaped binding site for ubiquitin.

174 al carceplex can be assembled by linking two bowl-shaped calix[4]arenes via four dimetal units, (DAni

175 The molecular structures of bowl-shaped carbocations 1 and 2 crystallized as salts w

176 a nanocontainer, which is built up from six bowl-shaped cavitands that are connected together with 1

177 The cation is situated in the bowl-shaped cavity of calix[4]arene.

178 g additional trimer contacts and filling the bowl-shaped concavity observed at the tip of the DEN-2 s

179 The fused bowl-shaped corannulene provides these porphyrins with a

180 a structural motif based on a C(3)-symmetric bowl-shaped core, on which three substituted amino acids

181 Dimerization leads to a large, bowl-shaped crevice, which might be involved in vivo in

182 The data for tripeptide amides fit bowl-shaped curves; an example is N-t-Boc-Val-Pro-Arg-7-

183 for hydroxycobalamin is located in a shallow bowl-shaped depression at the C-terminal end of the beta

184 erosion that, on Earth, are characterized by bowl-shaped depressions several tens of centimetres acro

185 YdaH is a bowl-shaped dimer with a solvent-filled basin extending

186 sisting of 12-fold gp14 adaptor ring, 8-fold bowl-shaped gp15, and 4-fold gp16 tip.

187 At 1200 degrees C, the bowl-shaped hydrocarbon 1 rearranges to the planar isome

188 macrocycle-templating strategies to isolate bowl-shaped metallocavitands, and highlights interesting

189 Here, the synthesis of a bowl-shaped molecule is described and evidence of its re

190 atrylene analogues (CTVs) are supramolecular bowl-shaped molecules known for their ability to complex

191 Metal detector: a bowl-shaped nanomolecule (see picture; S yellow, C gray,

192 Bowl-shaped pi-conjugated compounds offer the possibilit

193 efficient bottom-up strategy toward a novel bowl-shaped polycyclic aromatic hydrocarbons (PAH) C34 w

194 calibrated heretofore against X-ray data for bowl-shaped polycyclic aromatic hydrocarbons (PAHs).

195 tal, solvent-exposed position into the flat, bowl-shaped S2' pocket.

196 We report here the bowl-shaped structure of angiostatin kringles 1-3, the f

197 The bowl-shaped structure of methylene-bridged indenocorannu

198 The bowl-shaped structure was unambiguously determined by X-

199 Prc forms a monomeric bowl-shaped structure with a lid-like PDZ domain connect

200 concave encapsulation of a metal ion by two bowl-shaped sumanenyl anions in [Cs(C21 H11(-) )2 ](-) w

201 The bowl-shaped surface near the FMN-binding site is likely

202 The transporter is a bowl-shaped trimer with a solvent-filled extracellular b

203 lassifying the contour and shape as concave (bowl-shaped) or inflective (S-shaped contour with >/=1 i

204 tuted heteroacepentalenides leads to chiral, bowl-shaped, 10 pi aromatic species.

205 All molecules are bowl-shaped, and the pentalene isomers, 2 and 4, are mos

206 rises exclusively from binding at the Ca(2+)-bowl site.

207 ty of merging the intrinsic properties of pi-bowls, specifically corannulene derivatives, with the ve

208 The structure exhibits a highly ordered bowl stacking that is unusual for corannulenes with acyc

209 helping to differentiate IBD from irritable bowl syndrome and for monitoring disease activity.

210 355) provide the framework for the "aromatic bowl" that serves as a trimethylamine-binding site in TM

211 expressed odd-cognate genes, sob and bowel (bowl), that encode proteins with highly conserved C2H2 z

212 es regulate the steady-state accumulation of Bowl, the downstream effector of this pathway.

213 Bowl, then, acts cell-autonomously, together with one or

214 the peri positions causes a deepening of the bowl, thus an increase in the bowl inversion barrier.

215 peri positions are repulsive and flatten the bowl, thus causing a decrease in the bowl inversion barr

216 ove the bowl and help transfer them into the bowl to be pumped through the center of the dodecameric

217 oss proximal leg segments, lines antagonizes bowl to promote Dl expression by relief-of-repression.

218 dicate that odd and sob are more likely than bowl to share overlapping developmental roles, some func

219 estigated by dynamic NMR analysis, showing a bowl-to-bowl inversion energy (DeltaG()) of 16.7 kcal mo

220 A bowl-to-bowl inversion for a C70 fragment in solution wa

221 bilizing the planar transition state for the bowl-to-bowl inversion of (ethyl)corannulene (which acce

222 The transition state structure for bowl-to-bowl inversion of 1 is planar (D(2)(h)()) and li

223 Catalysis of the bowl-to-bowl inversion processes that pertain to corannu

224 ocess and empirical models suggest that Dust-Bowl-type droughts today would have unprecedented conseq

225 ologies composed of spike-, hemisphere-, and bowl-type subunit nanotopographies, respectively, the ra

226 In addition, we explore the coexisting bowl-up and -down conformations with respect to host-gue

227 re we show for sumanene on Ag(111) that both bowl-up and bowl-down conformations can be stabilized.

228 site and that Mg(2+) can bind to the calcium bowl with less affinity than Ca(2+).

229 DFT calculations predict that 5 exists as a bowl, with all six substituents intramolecularly H-bonde