ライフサイエンスコーパス: brain-specific

1 that these changes in lipid metabolism were brain specific.

2 part of UBE3A-ATS, which overlaps UBE3A, is brain specific.

3 rminus Ca(2+) sensing domain, which appeared brain-specific.

4 type IV NRG1 protein of 66 kDa was similarly brain-specific.

5 orms are ubiquitously expressed, while G2 is brain-specific.

6 kb retina-specific transcript (RGS9-1) and a brain specific 2.5kb transcript (RGS9-2).

7 Neurabin I is a brain-specific actin-binding protein.

8 l CaM kinase domain of CASK binds to a novel brain-specific adaptor protein called Caskin 1.

9 Here, we report that the SGK1 gene encodes a brain-specific additional isoform, SGK1.1, which exhibit

10 We have identified 25 brain-specific alternative cassette exons, compiled a da

11 vides further insight into the mechanisms of brain-specific alternative splicing and their possible p

12 Like SCG10, RB3 is brain-specific, although in situ hybridization results s

13 bnormal accumulation within muscle fibers of brain-specific Alzheimer type proteins.

14 s a PIP 5-phosphatase that is expressed in a brain-specific and a ubiquitous splice variants and is t

15 Stargazin is brain-specific and, like other neuronal Ca2+-channel sub

16 we identified the G-protein coupled receptor brain-specific angiogenesis inhibitor (BAI3) as a cell s

17 Here we identify brain-specific angiogenesis inhibitor 1 (BAI1) as a rece

18 Here, we identify brain-specific angiogenesis inhibitor 1 (BAI1) as a syna

19 Here, we demonstrated that mice lacking brain-specific angiogenesis inhibitor 1 (BAI1) have seve

20 Brain-specific angiogenesis inhibitor 1 (BAI1), an orpha

21 his pathway involves the phagocytic receptor brain-specific angiogenesis inhibitor 1 (BAI1), which re

22 Two of these proteins, brain-specific angiogenesis inhibitor 1 and protein kina

23 tion between adult ADHD and the gene BAIAP2 (brain-specific angiogenesis inhibitor 1-associated prote

24 C1ql1 specifically binds to the brain-specific angiogenesis inhibitor 3 (Bai3), which is

25 g et al. show that the fifth member, BAIAP3 (brain-specific angiogenesis inhibitor I-associated prote

26 Brain-specific angiogenesis inhibitor-1 (BAI1) is an adh

27 These results advance the understanding of brain-specific angiogenic regulation, and suggest that V

28 ed RNA interference or through disruption of brain-specific Ank3 in a heterozygous knockout mouse.

29 ant difference in cerebellar expression of a brain-specific ANK3 transcript.

30 e the distribution of PDE4s in the mammalian brain, specific antibodies were generated against the pr

31 In HD post-mortem brain, specific antibody reagents detect each partner in

32 The conventional APC and brain-specific APC isoforms suppress the tumorigenic phe

33 The protein kinase Mzeta (PKMzeta), a brain-specific atypical protein kinase C isoform, is imp

34 Multiple sclerosis (MS) is brain-specific autoimmune disease mediated by T helper (

35 Here, we addressed the importance of the brain-specific auxiliary subunit of HCN1, TRIP8b, in reg

36 amyloid precursor protein, whereas tau is a brain-specific, axon-enriched microtubule-associated pro

37 omologous beta1a subunit or the cardiac- and brain-specific beta2a subunit fully restored the L-type

38 skeletal muscle-specific beta1a, the cardiac/brain-specific beta2a, or beta2a/beta1a chimeras.

39 We have shown that the brain-specific beta4 subunit modulates the voltage depen

40 ysin-related sequences that were included in brain-specific BIN1 species, also termed amphiphysin iso

41 Decreased whole-brain specific binding of [3H][d-Ala2]deltorphin II, but

42 l to show that lack of astrocytic laminin, a brain-specific BM component, induces BBB breakdown.

43 The brain-specific, brain-enriched hyaluronan binding (BEHAB

44 insoluble active zone component; and ERC2 is brain-specific but exclusively localized to active zones

45 e biochemical and functional evidence that a brain-specific, C-terminal truncated and therefore fast

46 ) of cocaine-preexposed mice and the role of brain-specific Ca(v)1.2 and Ca(v)1.3 L-type Ca(2)(+) cha

47 The blood-brain barrier (BBB) is the brain-specific capillary barrier that is critical for pr

48 Recent evidence suggests that the brain-specific carnitine:palmitoyl-CoA transferase-1 (CP

49 We identified a novel 10 kb brain-specific cDNA interrupted by a balanced translocat

50 s delivery system with drug release into the brain-specific cell type could be useful for treatment o

51 he complex communication network between the brain-specific central clock and the tissue-specific per

52 Cytochrome P450 46A1 (CYP46A1) is a brain-specific cholesterol 24-hydroxylase responsible fo

53 These findings suggest a brain-specific cis-regulatory transcriptional effect of

54 rms of a protein homologous to the mammalian brain-specific clathrin-adaptor protein AP180.

55 In a mouse model, brain-specific coexpression of DNAJB6 delays polyQ aggre

56 from baseline to 24 weeks, particularly, for brain specific concerns with a trend for improvement in

57 he CAGGS promoter and was activated by using brain specific Cre-mediated recombination.

58 Here we show that brain-specific Crmp2 knockout (cKO) mice display molecul

59 N2 and HAPLN4) were physically linked to the brain-specific CSPG genes encoding brevican and neurocan

60 e alternative N-terminal splice forms of the brain-specific cytoplasmic protein TRIP8b and demonstrat

61 ted a new conditional knock-out mouse with a brain-specific deletion of Adk (Adk(Deltabrain)).

62 Here we test the effects of brain-specific deletion of dystroglycan, and show distin

63 EpoR knock-down animals, we demonstrate that brain-specific deletion of EpoR leads to significantly r

64 Brain-specific deletion of Mecp2 at embryonic day (E) 12

65 Brain-specific deletion of POMT2 resulted in hypoglycosy

66 uman neuropathy target esterase (NTE), and a brain-specific deletion of SWS/NTE in mice causes a simi

67 Finally, brain-specific deletion of the paternal, but not materna

68 nanoparticles with peptide ligand alters the brain specific delivery of encapsulated molecules.

69 re, these nanoplexes appear to be suited for brain-specific delivery of appropriate siRNA for therapy

70 the cell penetrating peptide TAT facilitates brain-specific delivery that is restricted to brain vasc

71 Reduction of Six3 function causes brain-specific deregulation of Nodal pathway activity, r

72 The brain-specific Disabled-1 (Dab1) functions in positional

73 lthough HD has historically been viewed as a brain-specific disease, htt is expressed ubiquitously, a

74 axia, spasticity, and dystonia, hallmarks of brain-specific disease.

75 We determined whether the brain-specific disruption of the FKBP12 gene in mice alt

76 Expression analyses confirmed the brain-specific distribution of NEGR1 including strong ex

77 on of Mst1/2 fully rescued the phenotypes of brain-specific Dlg5 knockout mice.

78 Auxilin is a brain-specific DnaJ homolog that is required for Hsc70 t

79 Brain-specific Drp1 ablation caused developmental defect

80 Some genes show brain-specific DS-DM, while others show stronger DS-DM i

81 he presynaptic compartment attributed to the brain-specific dynamin isoform, dynamin-1, is in synapti

82 synapses during development, and identify a brain-specific endocytic adaptor that confers spatiotemp

83 ifically in the nine autoimmune diseases and Brain-specific enhancer activities exclusively in Schizo

84 easing-level enhancer orthologues show fetal-brain-specific enhancer activity.

85 CPT1c, a brain-specific enzyme with high sequence similarity to C

86 c ERCs bind to RIMs, but both ubiquitous and brain-specific ERCs bind to Rab6, a GTP-binding protein

87 Only brain-specific ERCs bind to RIMs, but both ubiquitous an

88 ng 9a or 9d but has little effect with 9c, a brain-specific exon.

89 on to a control group of constitutive exons, brain-specific exons were often found to possess the fol

90 this model we would expect that enhancers of brain-specific expression of Igf2 would lie 5' of the IC

91 Northern blot analysis revealed a brain-specific expression pattern of p200RhoGAP.

92 thern blot analysis of human BHLHB5 revealed brain-specific expression with the highest abundance in

93 ven by fusion of the promoter of a gene with brain-specific expression, TTYH1, to C19MC, the largest

94 hed hyaluronan binding (BEHAB)/brevican is a brain-specific extracellular matrix protein containing a

95 This work demonstrates a role for a brain-specific extracellular matrix protein in glioma in

96 el of inclusion formation and indicates that brain-specific factors are not necessary for this proces

97 ted that a cis-element (-489 to -467) in the brain-specific fibroblast growth factor (FGF)-1 promoter

98 ch disrupt insulin signaling and may cause a brain-specific form of diabetes as part of an overall pa

99 which is increasingly being recognized as a brain-specific form of diabetes.

100 In this study we have identified the first brain-specific function for a neuronal adaptor complex.

101 pected, suggesting that Mints 1 and 2 have a brain-specific function related to APP that is not execu

102 Here, we report the gene structure for the brain-specific gamma 4 subunit and its map position on a

103 The brain-specific gamma isoform of protein kinase C (Prkcc)

104 -specific expansion, and many viper TEs show brain-specific gene expression along with their nearby g

105 mannosyl glycan core structures and that its brain-specific gene expression is regulated by epigeneti

106 tical projection tomography to rapidly image brain-specific gene expression patterns in 3D at cellula

107 y machine-learning approach based on a human brain-specific gene network to present a genome-wide pre

108 Many gene loci, including that of Myc and a brain-specific gene, are anchored by the SATB1 network a

109 ed target sites in a number of pancreas- and brain-specific genes consistent with its restricted expr

110 Furthermore, we show that the codon usage of brain-specific genes has been selectively preserved thro

111 pG density regions, and were associated with brain-specific genes related to neuronal plasticity.

112 stitutions in humans than in chimpanzees for brain-specific genes relative to other genes in the geno

113 This contig also contains two brain-specific genes, doublecortin (HGMW-approved symbol

114 ere is little overlap among the five sets of brain-specific genes, none of them supports human accele

115 on and neuronal function, thereby increasing brain-specific genetic mosaicism.

116 Combining a brain-specific genetic Xist ablation with short-term 5-a

117 the transgene is under the influence of the brain-specific GFAP promoter.

118 Collybistin is a brain-specific guanine nucleotide exchange factor (GEF)

119 al synapses is critically dependent upon the brain-specific guanine nucleotide exchange factor Collyb

120 Kalirin is a brain-specific guanine-nucleotide exchange factor (GEF)

121 ch appear to be paralogues of the X-encoded, brain-specific GyK isoform and are expressed only in the

122 Furthermore, the two brain-specific HAPLN genes (HAPLN2 and HAPLN4) were phys

123 Knockout (KO) of the brain-specific HCN-channel auxiliary subunit tetratricop

124 SIRT1 deacetylates the brain-specific helix-loop-helix transcription factor NHL

125 The brain-specific heterotrimeric G protein Go, which may be

126 recerebellin (Cbln1) is the precursor of the brain-specific hexadecapeptide cerebellin.

127 The expression of a brain-specific high-affinity Na+-dependent (and Cl--depe

128 gamma-Hydroxybutyric acid (GHB) binding to brain-specific high-affinity sites is well-established a

129 cription factors glucocorticoid receptor and brain-specific homeobox factor.

130 ected POU domain transcription factor Brn3b (brain-specific homeobox/POU domain protein 3b) plays suc

131 n 20, retinoid-related orphan receptor beta, brain-specific homeobox/POU domain protein 3b, Ets varia

132 ive regulator for exon splicing, whereas the brain-specific homolog of PTB, termed nPTB, promotes exo

133 PTBP1 and its brain-specific homologue polypyrimidine tract-binding pr

134 Using brain-specific IkappaB kinase beta knockout mice, it was

135 We now show that SynCAM is a brain-specific, immunoglobulin domain-containing protein

136 Expression of ATP1B4 genes is brain-specific in teleost fishes, whereas it is predomin

137 Brain-specific inactivation of these genes individually

138 Severe brain-specific inflammation and demyelination in DRB1*03

139 Although mechanisms leading to brain-specific inflammation and T cell activation have b

140 Both exogenous and brain-specific inhibitors of CaMKII accelerate voltage-d

141 Taken together, the current studies on the brain-specific insect P450 involved in deltamethrin resi

142 tivity, we established where and when in the brain specific internal knowledge conceptually interpret

143 At 22 months of age, brain-specific Irs2 knockout mice were overweight, hyper

144 The brain-specific isoform carnitine palmitoyltransferase 1C

145 However, it is unclear whether the brain-specific isoform CPT1C, which is located in the en

146 carnitine palmitoyltransferase 1C (CPT1C), a brain-specific isoform located in the endoplasmic reticu

147 The brain-specific isoform neuroplastin-65 co-localizes with

148 phin complex, the localization of the 71-kDa brain-specific isoform of dystrophin was assessed by imm

149 gion of tryptophan hydroxylase-2 (TPH2), the brain-specific isoform of the enzyme responsible for the

150 Pak5 (p21-activated kinase 5) is a brain-specific isoform of the group II Pak kinases whose

151 Synaptotagmin IV (Syt IV) is a brain-specific isoform of the synaptotagmin family, the

152 FX4_v3 (regulatory factor X4 variant 3) is a brain-specific isoform of the transcription factor RFX4.

153 e first produced an antibody against TPH2, a brain-specific isoform of tryptophan hydroxylase (seroto

154 ated on synaptic vesicles (SCAMP 1), and one brain-specific isoform primarily localized to synaptic v

155 hin RGS9-1 that differs in sequence from the brain-specific isoform RGS9-2.

156 roduce several isoforms, including the major brain-specific isoform, BPAG1a.

157 lyses suggesting that classes II and III are brain-specific isoforms of NRG3.

158 the finding that NRG3 classes II and III are brain-specific isoforms predicted by rs10748842 risk gen

159 JNK3, a brain-specific JNK isoform, is activated under oxidative

160 Here, we report the cloning of actinfilin, a brain-specific Kelch protein, which interacts with F-act

161 esis under energy stress conditions, whereas brain-specific kinase (BRSK) promotes the establishment

162 ed a Cre-Lox strategy to generate 11betaHSD2 brain-specific knockout (Hsd11b2.BKO) mice, measuring bl

163 y the neuronal function of S1P, we generated brain-specific knockout mouse models in which S1P-lyase

164 have linked the Rbfox1 gene to autism, and a brain-specific knockout mouse revealed a critical role f

165 Brain-specific knockout of Sirt1 results in exacerbation

166 Here we demonstrate that mice with a brain-specific knockout of the insulin receptor (NIRKO m

167 In summary, we show that brain-specific leptin signaling is sufficient to reverse

168 Here we identify a brain-specific, leucine-rich-repeat protein with high af

169 tag (EST; AA331381) originally reported in a brain-specific library, Pitx3, and CBP, were confirmed t

170 ipid binding proteins or were present in the brain-specific list of tissue-enriched genes identified

171 The expression of TOX2 and a brain-specific long noncoding RNA RP1-269M15.3 in fronta

172 Furthermore, whole-brain-specific loss of Atg7 leads to presynaptic accumul

173 rate that the c.548G>T mutation results in a brain-specific loss of presenilin function due to decrea

174 of the FLNA poison exon in NPCs and causes a brain-specific malformation.

175 pts indicates that MT5-MMP is expressed in a brain-specific manner consistent with the origin of its

176 t analysis and inter-association analysis on brain-specific markers, and 2) identification of previou

177 odimer complex, indicating the presence of a brain-specific mechanism for ADAR3 dimerization.

178 The brain specific member of the metallothionein (MT) family

179 Delta-catenin is a brain-specific member of the adherens junction complex t

180 ain Enriched HyAluronan Binding)/brevican, a brain-specific member of the lectican family of chondroi

181 Here we show that delta-catenin, a brain-specific member of the p120 catenin subfamily, for

182 Cyclin-dependent kinase 5 (Cdk5) is a brain-specific membrane-bound protein kinase that is act

183 somal loci display developmentally regulated brain-specific methylation patterns which are lost in Sm

184 Bl6J mice led to increased expression of the brain-specific microRNA miR-128b, which disrupted stabil

185 Dysregulated expression of miR-219, a brain-specific microRNA, has been observed in neurodevel

186 A recent study has shown that miR-134, a brain-specific microRNA, is present in dendrites where i

187 Here we show that a brain-specific microRNA, miR-134, is localized to the sy

188 ponse binding protein (CREB) expression by a brain-specific microRNA, miR-134.

189 t lamin C expression, is down-regulated by a brain-specific microRNA, miR-9.

190 Here, we identify a brain-specific microRNA-miR-128-that represses NMD and t

191 ce of a putative binding site for miR-338, a brain-specific microRNA.

192 emoval of prelamin A transcripts by miR-9, a brain-specific microRNA.

193 he brain is low and is regulated by miR-9, a brain-specific microRNA.

194 ng of the mechanisms regulating the level of brain-specific microRNAs.

195 ng studies showed that NXF proteins bound to brain-specific microtubule-associated proteins (MAP) suc

196 We found that brain-specific miR-124 is expressed in microglia but not

197 expression of a family of miRNAs, including brain-specific miR-124a.

198 functional studies showed that silencing of brain-specific miR-134 using antisense oligonucleotides

199 Mammalian brain-specific miR-9 and miR-124 have been implicated in

200 It is known that brain-specific miR-9 is controlled transcriptionally; ho

201 One brain-specific miRNA, miR-124a, decreases the levels of

202 NMDA receptor signaling reduces levels of a brain-specific miRNA, miR-219, in the prefrontal cortex

203 iR-124, the most abundant and well-conserved brain-specific miRNA, was exclusively present presynapti

204 , including a large polycistronic cluster of brain-specific miRNAs, are DNA-methylated and are bound

205 Here, we examine the role of two brain-specific miRNAs, miR-219 and miR-132, in modulatin

206 eins in controlling the expression levels of brain-specific miRNAs.

207 We recently reported the identification of a brain-specific mitochondrial uncoupling protein homologu

208 ormed an extensive characterization of a new brain-specific model of severe forms of RASopathies, the

209 Thus, our study suggests that brain-specific modulation of PIP2 may offer a therapeuti

210 lated transcription coactivator 1 (TORC1), a brain-specific modulator of CREB activity.

211 understanding of neuroprotective therapy and brain-specific monitoring for critically ill pediatric p

212 morphism analysis confirmed that a prominent brain-specific mutation constituted approximately 10% of

213 Brain-specific mutations defined several families of rel

214 The patterns of brain-specific mutations in these families were consiste

215 The fundamental role of the brain-specific myelin transcription factor 1-like (MYT1L

216 freshly isolated astrocytes the presence of brain-specific Na+-dependent inorganic phosphate cotrans

217 cloning has recently identified a vertebrate brain-specific Na+-dependent inorganic phosphate transpo

218 mRNA in situ hybridization of brain-specific Nav subunits revealed the expression of N

219 plex activity but also identifies TRIM9 as a brain-specific negative regulator of the NF-kappaB pro-i

220 raging these genome-wide predictions and the brain-specific network, we demonstrated that the large s

221 y to the glycosaminoglycan-binding region of brain-specific neuroglycan C (32 % identity over 102 ami

222 In the post-embryonic Drosophila brain, specific neuron types derive from specific progen

223 additional transcript, Girk2D, appears to be brain-specific, not polyadenylated, and highly expressed

224 e report the identification in mouse of four brain-specific novel paternally expressed transcripts an

225 Our data suggest that type IV is a unique brain-specific NRG1 that is differentially expressed and

226 A (BPA, a plastics monomer), induces strong brain-specific overexpression of aromatase.

227 r signaling in the central nervous system by brain-specific overexpression of the human IL-1 receptor

228 several ion channels and the CACNA1A gene, a brain-specific P/Q-type calcium channel gene associated

229 The brain-specific PACSIN 1 is enriched at synapses and has

230 The brain-specific paternal expression from the ICR shows me

231 imal spinal cord pathology further confirmed brain-specific pathology.

232 gnaling through phospholipase Cgamma and the brain-specific PKC variant protein kinase M zeta (PKMzet

233 olyadenylation signal being nearly absent at brain-specific polyA sites.

234 We show that these iPSCs express brain-specific portions of the transcripts driven by the

235 Neurogranin (Ng) is a brain-specific postsynaptic calmodulin-binding protein i

236 Neurogranin (Ng) is a brain-specific, postsynaptically located protein kinase

237 B'beta is a brain-specific PP2A regulatory subunit that mediates dep

238 d then according to their involvement in the brain-specific PPI network and proposed new regulatory s

239 s and revealed 22 GWAS genes involved in the brain-specific PPI network.

240 of brain areas and developmental stages and brain-specific promoter and enhancer annotations.

241 we have produced transgenic mice bearing the brain-specific promoter of the human FGF1 gene joined to

242 expressed promoter, simian virus 40, or by a brain-specific promoter taken from the 5' flanking seque

243 nomic sequence, suggesting the presence of a brain-specific promoter within intron 1.

244 The WAVE-1 isoform is a brain-specific protein expressed in variety of areas inc

245 Sustained activation of the brain-specific protein kinase C (PKC) isoform protein ki

246 roteomic screen, we have identified NETO2, a brain-specific protein of unknown function, as an intera

247 nique clone of 1.4 kb, which encoded a 79-aa brain-specific protein that bound the catalytic domain o

248 hed protein tyrosine phosphatase (STEP) is a brain-specific protein tyrosine phosphatase that opposes

249 Here we show that Jerky is a brain-specific protein with a high expression level in n

250 Kalirin is a brain-specific protein, first identified through its int

251 We identified a brain-specific protein, which has been previously termed

252 analyses revealed that syndapin I binds the brain-specific proteins dynamin I, synaptojanin, and syn

253 Combinations of brain-specific proteins increase the sensitivity and spe

254 ing can be achieved by detection in blood of brain-specific proteins that extravasate when these endo

255 Previously, we showed that brain-specific PTP1B(-/-) mice are protected against hig

256 Mutations in the human doublecortin (DCX), a brain-specific putative signaling protein, cause X-linke

257 Rim1, a brain-specific Rab3a-binding protein, localizes to the p

258 ted by the higher test-retest variability of brain-specific radioactivity.

259 SynGAP is a brain-specific ras GTPase-activating protein that is an

260 resent study shows for the first time that a brain-specific receptor, GABA(B)R2 is present in human n

261 In excitatory synapses of the brain, specific receptors in the postsynaptic membrane l

262 normal vision, Drosophila-like 2 (ELAVL2), a brain-specific regulator of RNA stability, as presumptiv

263 The role of brain-specific regulatory subunits in neuronal different

264 The presence of a brain-specific renin isoform is evolutionally conserved,

265 al inflammation on the brain, and reported a brain-specific response characterised by increased trans

266 We describe a brain-specific RhoGAP splice variant, BARGIN (BGIN), whi

267 In brain, specific RNA-binding proteins (RBPs) associate wi

268 fically expressed in the brain, suggesting a brain-specific role in mRNA metabolism.

269 pII, a ubiquitously expressed isoform of the brain-specific SdpI.

270 in is a multidomain protein that serves as a brain-specific serine protease.

271 only expressed the ubiquitous mRNA isoform, brain-specific SGCE mRNA and epsilon-sarcoglycan protein

272 However, no brain-specific signature sequence was identified.

273 lude elements of the IC, suggesting that the brain specific silencing of Ube3a is due to multiple alt

274 It has been proposed that brain-specific silencing of the paternal UBE3A allele is

275 n this issue of Cell, Chang and Guarente use brain-specific SIRT1 knockout mice and transgenic mice o

276 Here, we developed a brain-specific Slc6a8 knockout mouse (Slc6a8-/y) as an a

277 a protein similar in sequence to a mammalian brain-specific sodium-dependent inorganic phosphate cotr

278 We validated our muscle-specific and brain-specific splice forms for known genes.

279 influence endocytosis in the same manner as brain-specific splice isoforms of Bin1, nor did it exhib

280 The brain-specific splice variant of Cdc42 (bCdc42) terminat

281 RGS9-2, a brain-specific splice variant of the RGS9 gene, is highl

282 Here, we show that cpg2 is a brain-specific splice variant of the syne-1 gene that en

283 ArgBP2, and its brain-specific splice variant, nArgBP2, are interactors

284 however, the precise contribution of the two brain-specific subunits Ca(v)1.2 and Ca(v)1.3 remains mo

285 Syntaphilin is a brain-specific syntaxin-binding partner first characteri

286 The test-retest variability of brain-specific (target minus nondisplaceable) radioactiv

287 ), we characterized mice with whole-body and brain-specific targeted deletion of Mrap2, both of which

288 l genetic redundancy between Src and Fyn for brain-specific targets suggests that these two kinases m

289 Recent development of an inducible brain-specific Tat transgenic mouse model has made it po

290 Dysregulation of the brain-specific tau protein kinase II is reported to play

291 Cutting edge brain-specific therapies, capable of circumventing the p

292 In addition, we identified a brain-specific transcript containing a novel, alternativ

293 Northern analysis identified a brain-specific transcript of approx. 7.5kb.

294 iated with sequence-dependent binding of the brain-specific transcription factors EMX2 and NKX6-1.

295 e findings suggest the novel hypothesis that brain-specific transcription of Ube3a-ATS is regulated b

296 oup; P=0.25), although the number of days of brain-specific treatments (e.g., administration of hyper

297 In contrast, late disruption of brain-specific Trpm7 after embryonic day 10.5 does not a

298 The brain-specific tyrosine phosphatase, STEP (STriatal-Enri

299 h water channels, we studied the extent of a brain-specific water channel, aquaporin-4 (AQP4), using

300 Here we describe the generation of a brain-specific XBP-1 conditional KO strain (XBP-1(Nes-/-