ライフサイエンスコーパス: branched

1 As a key integrator of shoot branching, BRANCHED 1 (BRC1) coordinates and is orchestrated by end

2 ith altered function of the class I TEOSINTE BRANCHED 1, CYCLOIDEA, PCF (TCP) transcription factors T

3 molecular enantioselective hydroamination of branched 1,3-dienes is reported.

4 Alkynes, branched 1,3-dienes, and bicyclic alkenes were also foun

5 s for the enantioselective hydroamination of branched 1,3-dienes.

6 agments, prepared by AGA, yielded a multiple-branched 151-mer polymannoside.

7 BALOs yield a highly branched 3D structure within 21 days of culture, mimicki

8 anched acid/branched alcohol, branched ester/branched acid and branched ester/branched alcohol ratios

9 sensory consequences are the decrease of the branched acid/branched alcohol, branched ester/branched

10 concentrations) and higher concentrations of branched acids.

11 rect coupling of the fusogenic ectodomain to branched actin assembly is sufficient to drive cell-cell

12 n-related protein (Arp)2/3 complex nucleates branched actin filament networks pivotal for cell migrat

13 Here we show that branched actin filament networks, the main pushing machi

14 WASP-activated Arp2/3 complex only nucleates branched actin filaments but means branched actin networ

15 Networks of branched actin filaments formed by Arp2/3 complex genera

16 ation factor that promotes polymerization of branched actin filaments.

17 ace, whereas APC knockdown nearly eliminates branched actin in growth cones and prevents growth cone

18 9S mutation (Rac1(P29S)) in melanoma hijacks branched actin network assembly to coordinate proliferat

19 sp1-bound Arp2/3 complex, thereby initiating branched actin network assembly.

20 rained multiscale model shows that a minimal branched actin network is sufficient to internalize endo

21 and dynamics of the Arp2/3 complex-mediated branched actin network.

22 f p14 triggers N-WASP-mediated assembly of a branched actin network.

23 AR/WAVE proteins and Arp2/3 complex assemble branched actin networks at the leading edge.

24 es regulate the assembly and architecture of branched actin networks both in vitro and in cells.

25 nucleates branched actin filaments but means branched actin networks must be seeded with an initial p

26 vigation involving APC-dependent assembly of branched actin networks on microtubule tips.

27 tes in Schizosaccharomyces pombe to assemble branched actin networks that drive endocytosis.

28 rotein 2/3 (Arp2/3) complex, which nucleates branched actin networks.

29 nd actin ring formation, dependent on ARP2/3 branched actin polymerisation.

30 s/tetramers and facilitating Arp2/3-mediated branched actin polymerization.

31 We show that branched actomyosin networks relax significantly more sl

32 iscuity could be leveraged to produce chiral-branched adipic acid analogs to generate branched, nylon

33 nched ester/branched acid and branched ester/branched alcohol ratios that occurs as the grapes ripen.

34 uences are the decrease of the branched acid/branched alcohol, branched ester/branched acid and branc

35 difiers were investigated: water, linear and branched alcohols, acetonitrile, acetone, toluene, and e

36 t system for the allylation of various alpha-branched aldehydes with different allylic alcohols.

37 or the direct asymmetric alpha-allylation of branched aldehydes.

38 ned hydrophobic pocket that is selective for branched aliphatic thioalcohol ligands.

39 <=C(26)) alkanes, longer-chain (>=C(16)) and branched alkanes, and polycyclic aromatic compounds (PAC

40 ved in terminal oxidation of both linear and branched alkanes.

41 ent core flanked by two thiophene rings with branched alkyl chains.

42 as been evaluated for a series of linear and branched alkyl iodides with increasing structural comple

43 antioselectivity are retained across diverse branched allylic acetates bearing normal alkyl or second

44 The selectivity for a branched alpha-C(sp(3))-alkylation product is also obser

45 Glu-PLGA is a branched (also known as star-shaped) polymer and determi

46 the linear chiral aldehyde over the achiral branched alternative.

47 he identification of a family of alternative branched amine coreactants, which raises the analytical

48 A new method for the synthesis of alpha-branched amines by reductive functionalization of tertia

49 nd atom-economical means to synthesize alpha-branched amines.

50 red for the second and rate-limiting step of branched amino acid catabolism and implicated in maple s

51 cal cystatin fold that assembles into highly branched amyloid matrices, comparable to those in vivo,

52 y a facile free-radical polymerization using branched and amphiphilic ionic compounds as reactive mon

53 we reproduce the characteristic shapes from branched and budded to invaginated structures.

54 This may be due to the complex, branched and highly sulfated structure of fucoidans, whi

55 u kidney rudiments, engineered ureteric buds branched and induced nephron formation; when grafted int

56 mply sequenced because they are often highly branched and lack a uniform structure.

57 zyme (Dbr1), which cleaves the 2'-5' bond of branched and lariat RNAs.

58 Absorption of IgM with laminarin or curdlan (branched and linear 1-3-beta-d-glucans, respectively) de

59 thetically useful resolution of a mixture of branched and linear nitrile isomers was also demonstrate

60 anine, a series of reactions lead to linear, branched, and dendritic structures that are released fro

61 t involves the use of high molecular weight, branched, and functionalized polymers for protein conjug

62 r triantennary GalNAc at the N-terminus (the branched architecture) or monomeric GalNAc moieties anch

63 There are clear roles for branched architectures in regulating proteasome-mediated

64 dict that actin self-organizes into a radial branched array with growing ends oriented toward the bas

65 ith many linear filaments rather than highly branched arrays.

66 Although stenting of non-branched arterial segments has acceptable clinical outco

67 C to decorate histones with ubiquitin chains branched at Lys11 and Lys48 (K11/K48-branched ubiquitin

68 tal dopaminergic neurons possess extensively branched axonal arbours.

69 ce brain connections depend on neurons whose branched axons target separate regions.

70 We identified anteiso-branched-C18 SO (meC18SO) as the primary product of the

71 ore complex symmetrically and asymmetrically branched carbohydrates essential for cellular recognitio

72 The branched carrier has multiple sites for drug conjugation

73 Using branched catechols likely found in pretreated lignin, we

74 coupled receptor, and DBT, a subunit of the branched chain alpha-keto acid dehydrogenase that is req

75 tes, at least in part due to accumulation of branched chain alpha-keto acids.

76 a 10 gene cluster responsible for increased branched chain amino acid fermentation in the co-culture

77 fat, or high-fat diet supplemented with 1.5X branched chain amino acids (BCAAs) by replacing carbohyd

78 Branched chain amino acids (leucine, isoleucine and vali

79 ), and enrichment in metabolic pathways (eg, branched chain amino acids and arginine biosynthesis) an

80 i produced leucine, isoleucine and valine as branched chain amino acids when grown on LBG hydrolysate

81 ysophosphatidylethanolamines, 5 ceramides, 3 branched chain amino acids, and 9 neurotransmitters).

82 ide of the co-culture with notable levels of branched chain and sulphur-containing amino acids.

83 The branched chain fatty acid (BCFA) concentration (15 to 18

84 ed normal fatty acids (n-MUFA) and saturated branched chain fatty acids (BCFA) are structurally chara

85 ed for a polymer model system of differently branched chain walking polyethylenes in five different s

86 metabolism, arginine/proline metabolism, and branched-chain AA (BCAA) metabolism at baseline.

87 to determine if supplementing VLP diets with branched-chain AA (BCAA) would reverse the negative effe

88 This gene encodes the E2 subunit of the branched-chain alpha-keto acid dehydrogenase (BCKDH) com

89 Branched-chain alpha-keto acids (BCKAs) are catabolites

90 ways involved in inflammation, fibrosis, and branched-chain amino acid (BCAA) catabolism; systemic ma

91 associated with reduced or borderline plasma branched-chain amino acid (BCAA) concentrations.

92 d correlations among metabolites involved in branched-chain amino acid (BCAA) degradation, trimethyla

93 ogenase (BCKDH) complex, a core component of branched-chain amino acid (BCAA) metabolism.

94 production, while it does not contribute to branched-chain amino acid (BCAA)-derived aldehyde biosyn

95 Evidence suggests a role for impaired branched-chain amino acid (BCAAs; isoleucine, leucine, v

96 A-B27-negative AAU, including an increase of branched-chain amino acid biosynthesis, that reflects di

97 Collectively, these results indicate that branched-chain amino acid catabolism contributes to TAG

98 Major metabolic pathways were branched-chain amino acid metabolism (partially independ

99 pts surrounding the current understanding of branched-chain amino acid metabolism and its role in can

100 deregulated in many cancers, with changes in branched-chain amino acid metabolism specifically affect

101 spiration, an ornithine-glutamine shunt, and branched-chain amino acid metabolism were hypothesized a

102 t-chain dicarboxylacylcarnitines (SCDA), and branched-chain amino acid plasma biomarkers were indepen

103 of genes related to vitamin B6 synthesis and branched-chain amino acid synthesis (Q(fdr) < .05).

104 ing dihydroxyacid dehydratase, important for branched-chain amino acid synthesis.

105 scovered a potential causal link between the branched-chain amino acid transferase BCAT-1 and the neu

106 -1.kg-1.180 min; P = 0.04; eta2p = 0.31] and branched-chain amino acids (BCAAs) [between-group differ

107 emonstrated, while it is yet unclear whether branched-chain amino acids (BCAAs) are a primary input o

108 Recent studies have shown that circulating branched-chain amino acids (BCAAs) are elevated in obese

109 Circulating branched-chain amino acids (BCAAs) associate with insuli

110 bs (n = 24) were enterally supplemented with branched-chain amino acids (BCAAs), carbohydrate (maltod

111 A preceded by reduced amino acid proline and branched-chain amino acids (BCAAs), respectively.

112 alpha-keto acids (BCKAs) are catabolites of branched-chain amino acids (BCAAs).

113 Branched-chain amino acids (BCAAs, i.e., valine, leucine

114 er biochemical inhibition of biosynthesis of branched-chain amino acids (precursors to branched-chain

115 posure to PFAS and increased serum levels of branched-chain amino acids (valine, leucine, and isoleuc

116 The metabolite 3-MOB along with related branched-chain amino acids demonstrated strong predictab

117 und reduced concentrations of vitamin B6 and branched-chain amino acids in PSC (P < .0001), which str

118 genotype and diet, with a unique increase in branched-chain amino acids in the Glyco(Hi) HFD group.

119 influenced starch and sucrose, nitrogen, and branched-chain amino acids metabolism pathways.

120 alyses the first step in the biosynthesis of branched-chain amino acids(1).

121 t-activity rhythm) and metabolic parameters (branched-chain amino acids, tryptophan pathway, phenylal

122 or activation and for feedback inhibition by branched-chain amino acids.

123 e availability of key nutrients like GTP and branched-chain amino acids.

124 Branched-chain ammonium salts showed lower affinity.

125 naceous plants secrete acylsugars, which are branched-chain and straight-chain fatty acids esterified

126 ome preferred straight-chain elongation over branched-chain elongation.

127 of branched-chain amino acids (precursors to branched-chain fatty acids) by imazapyr showed concentra

128 Intracellular BCKAs are cleared by branched-chain ketoacid dehydrogenase (BCKDH), which is

129 itches on insulin exocytosis for glucose and branched-chain oxoacids as secretagogues (it does so par

130 increased particle-particle repulsion due to branched chains and ligand polydispersity.

131 Akin to their homotypic counterparts, branched chains elicit a wide array of biological output

132 The activity and selectivity toward branched chains is markedly enhanced by the proteasomal

133 otes degradation of substrates modified with branched chains under multi-turnover conditions.

134 found to preferentially flow in single-file, branched chains within the POCs.

135 lightly higher M(w) but composing of shorter branched chains.

136 asome-associated deubiquitinase, cleaves K48 branched chains.

137 opening to bulk solvent and two hydrophilic branched channels.

138 mplexes with thiols of larger size and more "branched" chemical structure compared to complexes with

139 ity of MAR, we probed its utility to produce branched chiral diacids.

140 the architecture of the TSP1-TSP2-TSP3-TSP4 branched complex in CBA120 and its related ViI-like phag

141 an enzyme responsible for generating beta1,6-branched complex N-glycans, which serve as a major ligan

142 ized about 13-fold more efficiently than the branched conjugate into HepG2 cells, as demonstrated by

143 Branched conjugates loaded with up to 80 boron atoms per

144 ly, enhancement in thermal properties of the branched copolymer was observed, as the T(g) value incre

145 rs placed beside anatomic retinal landmarks (branched/curved vessels, fovea, or optic disc) mapped th

146 of branching for linear (DB, 0%), gradually branched (DB, <50%), hyperbranched (DB, 50%), and pseudo

147 we design positively charged Avidin grafted branched Dextran nanostructures that utilize long-range

148 gent [(P,N)Ni]-catalyzed hydroalkylations of branched dienes are reported.

149 oteins govern two pathways for resolution of branched DNA intermediates such that potentially deleter

150 a process that generates recombination-like branched DNA intermediates.

151 ANKLE1 is a nuclease that cleaves a range of branched DNA species.

152 lex loses its preference for ICL and related branched DNA structures, and becomes a sliding DNA clamp

153 n endonuclease that cleaves a broad range of branched DNA structures, including the Holliday junction

154 Both Uup and RadD bind to branched DNAs in vitro.

155 MutLgamma also binds various branched DNAs, including Holliday junctions, but does no

156 Accordingly, we demonstrated that the branched eDNA structures present within the biofilms for

157 ir for chronic dissection with a custom-made branched endograft.

158 Here, we highlight four branched epithelia that develop at different spatial sca

159 rease of the branched acid/branched alcohol, branched ester/branched acid and branched ester/branched

160 ed alcohol, branched ester/branched acid and branched ester/branched alcohol ratios that occurs as th

161 Branched esters of palmitic acid and hydroxystearic acid

162 hick dendrites; their distal dendrites often branched extensively and had long appendages.

163 er observe that HIPK4 overexpression induces branched F-actin structures in cultured fibroblasts and

164 2/3 complex is essential for the assembly of branched filamentous actin, but its role in physiology a

165 non-vaned grouped filaments and bilaterally branched filaments, hitherto considered unique to manira

166 This complex generates branched filaments, thereby changing the overall organiz

167 h vastly different wavelengths, for example, branched flow has been suggested as a focusing mechanism

168 stigation of a plethora of new ideas such as branched flow in nonlinear media, in curved space or in

169 Branched flow may act as a trigger for the formation of

170 of soap films leads to a regime in which the branched flow of light interacts and affects the underly

171 present the experimental observation of the branched flow of light.

172 Bringing branched flow to the field of optics, with its full arse

173 This fundamental wave phenomenon is known as branched flow.

174 into filaments that display the features of branched flow: scaling of the distance to the first bran

175 th in general is negatively regulated by the BRANCHED gene.

176 Here we show that the BRANCHED genes play opposing regulatory roles in tobacco

177 Glycogen, a branched glucose polymer, helps regulate glucose homeost

178 Polydextrose (PDX) is a branched glucose polymer, utilized as a soluble dietary

179 ray fluorescence intensity and complexity in branched glycan structures.

180 ate labeled linear maltooligosaccharides and branched glycans from human immunoglobulin.

181 endrimers containing more complex linear and branched glycans has so far prevented access to more rea

182 bility using bacterial cell membrane lipids (branched glycerol dialkyl glycerol tetraethers) and an a

183 , FlaB1 and FlaB3, which are modified with a branched, heptameric glycan at all N-linked sequons exce

184 SDFs of the samples were composed of heavily branched heteromannans (~60%), slightly branched pectic

185 port a modular synthetic route to linear and branched homoallylic amines that operates through a sequ

186 cortical cells of the roots, where they form branched hyphae called arbuscules that function in nutri

187 and LA2, adjacent to PDFLAs and PDFMEs that branched in LA3.

188 Multiple neuropeptide-ir interneurons branched in ME4, connecting the AME to ME2.

189 Engineered ureteric buds branched in three-dimensional culture and expressed Hoxb

190 ons, we found that: taller plants with fewer-branched inflorescences produced larger seeds; seed size

191 unction in different pathways to process the branched intermediates.

192 ity for the thermodynamically less favorable branched isomer.

193 plants were analyzed for 24 PFASs including branched isomers.

194 series of primary alcohols to disubstituted branched ketones.

195 nscriptional self-assembly of tiles based on branched kissing loops, and show that tiles inserted int

196 are linked through an artificially designed branched kissing-loop motif, involving Watson-Crick base

197 These catalysts have low linear-to-branched (L:B) regioselectivity for simple linear alkene

198 half of radially-migrating neurons exhibit a branched leading process, this being even more frequent

199 Through a chimeric approach, branched ligands also allow efficient optical control of

200 ntral and axial chirality, reaching complete branched/linear or exo/endo ratios and excellent diaster

201 We found that PDIM's methyl-branched lipid tails enabled it to spread into host epit

202 ulosis, employs atypical long (C(60-90)) and branched lipids to produce a complex cell wall and local

203 t of properties when compared with linear or branched macromolecules.

204 I(4)P generation and led to a hyperfused and branched mitochondrial network marked with extended mito

205 Our results therefore support a two-branched model for the daily synchronization of tissues:

206 a higher capacity for incorporation of alpha-branched monomer units than those previously identified

207 er, these methods have never been applied to branched monounsaturated FAME.

208 We find that the formation of branched morphologies relies strongly on junctional acti

209 heir elongation and led to structures with a branched morphology, differing from the predominantly li

210 Surprisingly, new branched MTs preferentially originate near the minus-end

211 te database for a TPP of any topology (e.g., branched, multicyclic, etc.).

212 Unbalance leads to formation of branched muscles, and this correlates with locomotor beh

213 rified via ion-exchange chromatography using branched N,N,N',N'-tetra-2-ethylhexyldiglycolamide.

214 By virtue of a branched N-acylamide side chain, GalNAzMe is not interco

215 sor for all complex N-glycans, including the branched N-glycans associated with cancer.

216 Galectins bind to branched N-glycans attached to cell surface glycoprotein

217 Modification of cell surface receptors with branched N-glycans coordinates cell growth and different

218 Elimination of branched N-glycans in developing B cells via targeted de

219 a single human-specific HA trimer to complex branched N-glycans, which is not possible for the avian-

220 Controlling the formation of nanosized branched nanoparticles with high uniformity is one of th

221 branch mechanism to form highly monodisperse branched nanoparticles, we vary the length of the nickel

222 a; however, due to its complexity and highly branched nature, the native structure remains partially

223 These results contrast with growth of branched NCs from single-crystalline seeds and provide a

224 ibutions of planar defects were used to grow branched NCs in order to understand how their distributi

225 l functions, concentrates at the microtubule-branched network interface, whereas APC knockdown nearly

226 These observations suggest that branched networks of RS1 may play a stabilizing role in

227 Also, branched networks undergo rare convulsive movements, "av

228 myosin filaments to Arp2/3 complex-nucleated branched networks, and this phenotype can be partially r

229 te and immobilize bundles from mobile Arp2/3-branched networks.

230 f mechanically linked filaments displayed by branched networks.

231 be iteratively acting, synthesizing diverse branched/nonbranched linear intermediates, and two of th

232 ral-branched adipic acid analogs to generate branched, nylon-like polymers with reduced crystallinity

233 Instead, each Pleistocene Siberian canid branched off the lineage that gave rise to present-day w

234 sly, modulates the kinetics of the transient branched oligomerization pathway that precedes nucleatio

235 philic Janus dendrimers and either linear or branched oligosaccharides containing up to six monosacch

236 C(29:0) fatty acids, including odd-chain and branched ones.

237 method for direct conversion of aldehydes to branched or linear alkyl ketones is described.

238 biquitin E3 ligases to conjugate heterotypic branched or mixed ubiquitin (Ub) chains on substrates of

239 by switching a couple of solenoid valves at branched outlets according to signals obtained by an opt

240 ta suggest that vertebrate NMD is a complex, branched pathway wherein individual branches regulate sp

241 vily branched heteromannans (~60%), slightly branched pectic polysaccharides (~25%), and xyloglucans

242 The percentage of branched perfluorooctane sulfonate increased with depth,

243 ctanesulfonic acid (nPFOS) 2.2% (2.0%-2.5%), branched perfluorooctanesulfonic acid (brPFOS) 3.0% (2.5

244 In comparison to linear PFECAs, branched PFECAs have a higher tendency of H/F exchange o

245 Branched PFOS isomers had average half-lives ranging fro

246 Branched PFOS isomers had shorter half-lives than linear

247 In addition, we report branched, photoswitch-fluorophore compounds for simultan

248 To overcome this, we developed a family of branched photoswitchable compounds to target metabotropi

249 Branched plasmonic nanocrystals (NCs) have attracted muc

250 platform for the synthesis of symmetrically branched plasmonic NCs.

251 hematical parameters for characterization of branched PLGA polymers and the validation of these param

252 such parameters have not been described for branched PLGA polymers.

253 as developed and validated using a series of branched-PLGA standards, and it was used to determine th

254 e validation of these parameters using known branched-PLGA standards.

255 cient approach for synthesizing well-defined branched poly(monothiocarbonate)s in a "grafting through

256 hen chiral ECH was utilized, semicrystalline branched poly(monothiocarbonate)s were accessible with a

257 nic acid (HA) forms dynamic cross-links with branched polyethylene glycol polymers end-functionalized

258 the inclusion of chelating agents or highly branched polymers may overcome these issues.

259 e strategy presented herein for synthesizing branched polymers provides efficient and concise access

260 on of glucose within glucose-PLGA (Glu-PLGA) branched polymers.

261 nts indicate the presence of complex, highly branched polysaccharide components with a wide range of

262 Pure, completely defined linear and branched polysaccharides are essential to understand car

263 onstrates exclusive regioselectivity for the branched position of the pai-allyl.

264 phase peptide chemistry was used to prepare branched precursors which were cyclized off-resin to obt

265 en that enable the preparation of linear and branched primary, secondary and tertiary amines includin

266 aromatic amines 3a-3l (200 mol%) to form the branched products of allylic amination 4a-4l and 5a-5l,

267 nantioselective methods are limited to form "branched" products.

268 ell illuminate the functional logic of other branched projection axon systems.SIGNIFICANCE STATEMENT

269 O) proteins to lysine side chains to produce branched proteins.

270 ased showing two distinct types in the skin: branched, putative Langerhans cells, and amoeboid cells.

271 atalysts that follow complex mechanisms with branched reaction pathways.

272 mma), which supports crossing over(8), binds branched recombination intermediates and associates with

273 der as water soluble fraction (WSF), rich in branched regions, and chelator soluble fraction (CSF), l

274 Herein, we describe an intermolecular direct branched-selective alpha-alkylation of cyclic ketones wi

275 n of a novel type of HCN donor, a practical, branched-selective, HCN-free transfer hydrocyanation was

276 a C. sporogenes for which the production of branched short-chain fatty acids was knocked out, we dis

277 ed and hemi-resolved DNA junctions and other branched species at the very late stages of mitosis.

278 1-4, attach to the phage baseplate forming a branched structure.

279 types contain amorphous oligomers leading to branched structures as well as prefibrillar oligomers.

280 ure conditions, EC form two-dimensional (2D) branched structures that can lead to a meshed pseudo-cap

281 proteins to overcome steric hinderance from branched substrates.

282 The synthesis of eukaryotic glycans - branched sugar oligomers attached to cell-surface protei

283 Linear and branched surfactants facilitated formic acid and CO prod

284 the molecular structure (linear, cyclic, or branched), the concentration, the average chain length,

285 physical mechanisms that are used to sculpt branched tissues.

286 Extensive cell projections branched to adjacent stromal cells and interacted with t

287 ession and therapy occurs in both linear and branched trajectories, with a clear order of mutational

288 Vancomycin, a branched tricyclic glycosylated peptide antibiotic, is a

289 recursors to give various homotypic and even branched Ub probes at multi-milligram scale.

290 chains branched at Lys11 and Lys48 (K11/K48-branched ubiquitin chains) that recruit p97 (also known

291 of ethylene is observed, leading to lightly branched ultra-high molecular weight polyethylene with M

292 for protein synthesis, to the proteinogenic, branched valine (Val) in their propensity to mistranslat

293 In this branched vascular network, WBCs have to strongly deform

294 s in that complete levels of N versus C3 and branched versus linear regioselectivity are observed.

295 essel networks as indicated by elongated and branched vessel structures, had increased graft-host ves

296 The reaction utilizes branched vinyl or alkynyl alpha-fluoro ketones that can

297 ordering, polymer nanopores), architecture (branched vs linear), functional groups (coordinating or

298 sed surface fish larvae were longer and more branched, while in both cave morphs the ventral dendrite

299 r proportion of hairy region that is heavily branched with arabinan and galactan side chains.

300 Xyloglucans were also densely branched with monomeric and/or dimeric side chains.