ライフサイエンスコーパス: branching morphogenesis

1 rearrangements that may contribute to renal branching morphogenesis.

2 egarding the function of these parameters in branching morphogenesis.

3 cell adhesion and motility during epithelial branching morphogenesis.

4 ammary fat pad are axially oriented prior to branching morphogenesis.

5 or the transcription factor Sox9 during lung branching morphogenesis.

6 racellular matrix (ECM) is a crucial step in branching morphogenesis.

7 distal compartment before the initiation of branching morphogenesis.

8 vs. mesenchymal cells in an organ undergoing branching morphogenesis.

9 7) supported gland survival and enhanced SMG branching morphogenesis.

10 ng candidate genes that potentially regulate branching morphogenesis.

11 edback inhibition and thus regulated mammary branching morphogenesis.

12 ic modes used during growth factor-initiated branching morphogenesis.

13 via epithelial-mesenchymal interactions and branching morphogenesis.

14 complex activity is required for subcellular branching morphogenesis.

15 an upstream regulator of Grem1 in initiating branching morphogenesis.

16 GREM1 protein restores ampulla formation and branching morphogenesis.

17 n linking mechanosensing to endothelial cell branching morphogenesis.

18 y coordinated with ASM formation during lung branching morphogenesis.

19 xerts an inhibitory effect on salivary gland branching morphogenesis.

20 pecification of basal cell number influences branching morphogenesis.

21 g in the blastema, which undergoes extensive branching morphogenesis.

22 s HS modification is important for robust UB branching morphogenesis.

23 e identified Btbd7 as a dynamic regulator of branching morphogenesis.

24 al ducts extend into the fat pad and undergo branching morphogenesis.

25 g new opportunities for future research into branching morphogenesis.

26 mammalian lung are generated by a process of branching morphogenesis.

27 ncreasing proximal-to-distal gradient during branching morphogenesis.

28 epithelium from the bud stage and throughout branching morphogenesis.

29 ream of Ret that promotes and controls renal branching morphogenesis.

30 role for Klf6 in the regulation of prostate branching morphogenesis.

31 epimorphin/syntaxin-2 can stimulate mammary branching morphogenesis.

32 significantly increased ductal extension and branching morphogenesis.

33 emodeling in high-density gels, resulting in branching morphogenesis.

34 ical and morphological changes necessary for branching morphogenesis.

35 normal mammary epithelial proliferation and branching morphogenesis.

36 s required for mammary epithelial growth and branching morphogenesis.

37 mal microenvironment regulates mammary gland branching morphogenesis.

38 eolysis with epithelial proliferation during branching morphogenesis.

39 e epithelium, were associated with increased branching morphogenesis.

40 eading to more aggressive cell outgrowth and branching morphogenesis.

41 tions and possibly cell rearrangement during branching morphogenesis.

42 endoderm undergoes extensive and stereotypic branching morphogenesis.

43 both pyrethroids, including some relating to branching morphogenesis.

44 remarkably conserved set of tools to undergo branching morphogenesis.

45 t layers, resulting in an arrest of vascular branching morphogenesis.

46 imal part, undergo shape change and initiate branching morphogenesis.

47 ote subsequent splitting of the tip to allow branching morphogenesis.

48 together in the lung mesenchyme to maintain branching morphogenesis.

49 hich inhibits p38MAPK activity and decreases branching morphogenesis.

50 -level regulatory network essential for lung branching morphogenesis.

51 wn function for Fgf20 in mammary budding and branching morphogenesis.

52 model in which these cell movements mediate branching morphogenesis.

53 of epithelial progenitor cells that impairs branching morphogenesis.

54 uired for terminal bifurcation during airway branching morphogenesis.

55 lium develops into a tree-like structure via branching morphogenesis.

56 y proteins are regulators of cell growth and branching morphogenesis.

57 as well as a severe disruption of labyrinth branching morphogenesis.

58 abilize pouch epithelial cells at the end of branching morphogenesis.

59 d physical mechanisms that can contribute to branching morphogenesis.

60 howed increased proliferation and precocious branching morphogenesis.

61 mbly and governs rates of cell migration and branching morphogenesis.

62 through actomyosin contractility to support branching morphogenesis.

63 al differentiation and subsequent epithelial branching morphogenesis.

64 rostate specification, ductal outgrowth, and branching morphogenesis.

65 and are required in cleft progression during branching morphogenesis.

66 Branching morphogenesis, a fundamental process in the de

67 from the ureteric bud (UB), which undergoes branching morphogenesis, a process regulated by multiple

68 , recombinant collagen IV NC1 domains rescue branching morphogenesis after MT2-siRNA treatment, incre

69 n lung hypoplasia characterized by defective branching morphogenesis, altered cellular energetics and

70 One such role is in inhibition of lung branching morphogenesis, although the precise mechanism

71 oskeletal regulators required for intestinal branching morphogenesis and a modulator of bioactive sph

72 We find a negative correlation between branching morphogenesis and alveolar differentiation tem

73 ial progenitors continuously balance between branching morphogenesis and alveolar differentiation, an

74 nificant associations between the profile of branching morphogenesis and both cancer models.

75 ical modeling has been limited to acinar and branching morphogenesis and breast cancer, without refer

76 regarding sexual dimorphism, bud induction, branching morphogenesis and cellular differentiation.

77 kinase activation, impaired prostatic ductal branching morphogenesis and compromised cell proliferati

78 However, JNK1/2 deficiency caused increased branching morphogenesis and defects in the clearance of

79 and uncover the critical function of Dlg5 in branching morphogenesis and differentiation of lung prog

80 y 18.5, SMGs from wild-type mice showed duct branching morphogenesis and differentiation of tubule du

81 ervous and immune systems and salivary gland branching morphogenesis and discuss new insights concern

82 /loxP) mice exhibited significant defects in branching morphogenesis and ductal outgrowth compared wi

83 hown that Cripto-1 is involved in regulating branching morphogenesis and epithelial-mesenchymal trans

84 in the prostate epithelium is important for branching morphogenesis and for the acquisition of the a

85 Both LIMK 1 and 2 were necessary for branching morphogenesis and functioned to promote epithe

86 e report that Gpr54 deletion leads to kidney branching morphogenesis and glomerular development retar

87 plays an important role in embryonic kidney branching morphogenesis and glomerular development.

88 longing to the MT-MMP and ADAMTS families in branching morphogenesis and interdigital web regression.

89 ptor (Smed-EGFR-5) as a crucial regulator of branching morphogenesis and maintenance.

90 RP2/FAK signaling axis that is important for branching morphogenesis and mammary gland development.

91 such as CD44 that are important for prostate branching morphogenesis and metastasis to the bone micro

92 disorder characterized by defective ureteric branching morphogenesis and nephrogenesis, ranks as one

93 erful and quantitative means to characterize branching morphogenesis and nephrogenesis.

94 ression of Sprouty2 (SPRY2), an inhibitor of branching morphogenesis and neurite outgrowths.

95 t mice have gross defects in chorioallantoic branching morphogenesis and placental vascular patternin

96 ELF5 during early lung development disrupted branching morphogenesis and produced a dilated epitheliu

97 The lacrimal gland (LG) develops through branching morphogenesis and produces secretions, includi

98 e kinase protein Dlg5 is required for proper branching morphogenesis and progenitor differentiation i

99 evelopment with lung buds failing to undergo branching morphogenesis and progressive atrophy of the p

100 signals in prostate epithelial cells promote branching morphogenesis and proliferation, and that aber

101 nducible loss of Dnm2 in endothelium impairs branching morphogenesis and promotes the accumulation of

102 t not Smad5, resulted in retardation of lung branching morphogenesis and reduced sacculation, accompa

103 istinct morphogenetic processes: subcellular branching morphogenesis and subcellular apical lumen for

104 lpha3 chain-containing LMs promote normal UB branching morphogenesis and that LM-332 is a better subs

105 the structure of the gene network during UB branching morphogenesis and the mechanisms involved in t

106 Aberrant branching morphogenesis and tubulogenesis were also obse

107 Embryonic metanephric kidneys also undergo branching morphogenesis and Vangl2 is known to be expres

108 ration level of salivary cells, disorganized branching morphogenesis, and a lack of differentiated mu

109 ic progenitor cell proliferation, defects in branching morphogenesis, and a subsequent failure to ind

110 al paracrine modulator of epithelial growth, branching morphogenesis, and epithelial gene expression.

111 ving the complex dynamics of epithelial cell branching morphogenesis, and in nephron patterning.

112 l step in submandibular salivary gland (SMG) branching morphogenesis, and may result from localized a

113 developmental stages of prostate induction, branching morphogenesis, and secretory differentiation.

114 -epithelial transition, inductive signaling, branching morphogenesis, and segmentation.

115 he molecular signaling pathways that control branching morphogenesis appear to be conserved across or

116 Here, the principles of branching morphogenesis are exemplified by the mammary g

117 h the mechanisms by which they contribute to branching morphogenesis are not defined.

118 Budding, lobation and branching morphogenesis are unaffected in early stage Fg

119 e of mammary stem cells (MaSCs), which drive branching morphogenesis, are unknown.

120 analysis of gene expression data identified branching morphogenesis as a biological process sensitiv

121 The lungs are generated by branching morphogenesis as a result of reciprocal signal

122 rgeted deletion impairs ductal expansion and branching morphogenesis as well as cell proliferation in

123 Npas3-null mice have reduced lung branching morphogenesis but are viable prenatally.

124 ranscription factor NFIB is not required for branching morphogenesis but plays a key role in tubule c

125 lation of endothelial cell proliferation and branching morphogenesis, but how this coordinated regula

126 gland, lumen formation takes place alongside branching morphogenesis, but in a controlled manner, so

127 rm and the underlying mesenchyme during lung branching morphogenesis, but little is known about how t

128 Proteolysis is essential during branching morphogenesis, but the roles of MT-MMPs and th

129 Eda regulates mammary placode formation and branching morphogenesis, but the underlying molecular me

130 enchymal interactions play a crucial role in branching morphogenesis, but very little is known about

131 clude that Sox9 collectively promotes proper branching morphogenesis by controlling the balance betwe

132 naling through Pak2a thus signals the end of branching morphogenesis by increasing intercellular adhe

133 er, these data demonstrate that Ilk controls branching morphogenesis by regulating the expression of

134 sal polarity, and epithelial motility during branching morphogenesis can be applied to understand the

135 mesenchyme leads to ectopic and disorganized branching morphogenesis caused by beta-catenin directly

136 ntify kidney-specific and shared programs of branching morphogenesis, comparative expression studies

137 Branching morphogenesis creates arborized epithelial net

138 g MT-MMP activity during submandibular gland branching morphogenesis decreases proliferation and incr

139 defects in the epithelium including reduced branching morphogenesis, delayed proliferation, and incr

140 e imaging and transcriptome analysis of lung-branching morphogenesis demonstrate that Fzd2 promotes c

141 In the lacrimal gland, branching morphogenesis depends on the interaction of he

142 Branching morphogenesis depends on the precise temporal

143 not invade through the basement membrane and branching morphogenesis does not take place.

144 he vasculature, the developmental program of branching morphogenesis during angiogenesis is controlle

145 Macrophages are important regulators of branching morphogenesis during development and postnatal

146 Thus beta1 integrins can regulate organ branching morphogenesis during development by mediating

147 tyrosine kinase is crucial for ureteric bud branching morphogenesis during kidney development, yet f

148 rized invasion of trophoblasts and efficient branching morphogenesis during placental development, bu

149 ns as a polarity protein required for proper branching morphogenesis during placental development.

150 letal dynamics that mediate endothelial cell branching morphogenesis during vascular guidance are tho

151 and late lung development that affect airway branching morphogenesis, epithelial cell differentiation

152 n has long been thought to drive stereotypic branching morphogenesis even though isolated lung epithe

153 Expression of genes involved in branching morphogenesis, Gcm1, Syna and Synb, and in pat

154 gands act as solid-phase agonists to promote branching morphogenesis, growth and water transport func

155 While the genetic control of renal branching morphogenesis has been extensively described,

156 The mechanisms that control axonal branching morphogenesis have been studied intensively, y

157 ature co-develops with the epithelium during branching morphogenesis; however, it is not known whethe

158 lium through targeted deletion leads to poor branching morphogenesis, impaired terminal end bud forma

159 rved that VEGF(165), an NRP2 ligand, induces branching morphogenesis in 3D cultures and that branchin

160 of breast cancer cells and induces abnormal branching morphogenesis in 3D cultures.

161 Knockdown of pleiotrophin influenced lung branching morphogenesis in a fetal lung organ culture mo

162 ng hypothesis that directional outgrowth and branching morphogenesis in a variety of tissues are infl

163 regulates the normal invasive mammary gland branching morphogenesis in an epithelial cell extrinsic

164 Defects in airway branching morphogenesis in association with impaired epi

165 function as "switches" to regulate stages of branching morphogenesis in developing mammalian organs,

166 rate that ACKR2 is an important regulator of branching morphogenesis in diverse biological contexts a

167 ts receptor Met have been shown to stimulate branching morphogenesis in explanted embryonic kidneys,

168 Antisense knockdown of Adamts16 inhibited branching morphogenesis in kidney organ cultures.

169 and Notch are crucial for tube formation and branching morphogenesis in many systems, but the specifi

170 rmore, Malat1 loss results in a reduction of branching morphogenesis in MMTV-PyMT- and Her2/neu-ampli

171 l as similarities to Ras-mediated control of branching morphogenesis in more complex organs, includin

172 Considering the importance of branching morphogenesis in multiple taxa, our findings h

173 Exogenous FGF10 rescues branching morphogenesis in Npas3-null lungs.

174 outcome showed that the process of vascular branching morphogenesis in Ott1-deficient animals was re

175 ics parameters in endothelial cells to guide branching morphogenesis in physically complex ECMs.

176 to restore impaired arterial development and branching morphogenesis in synectin-deficient mice and s

177 has also enabled the factors that influence branching morphogenesis in the embryonic and pubertal gl

178 rameters regulating cleft progression during branching morphogenesis in the epithelial tissue of an e

179 Therefore, PTPRB regulates branching morphogenesis in the mammary epithelium by mod

180 Branching morphogenesis in the mammary gland is achieved

181 MMP3 has been shown to regulate branching morphogenesis in the mammary gland.

182 NF2, LATS1/2 and YAP play a critical role in branching morphogenesis in the mouse kidney.

183 demonstrate that PTPRB negatively regulates branching morphogenesis in the mouse mammary epithelium.

184 he isolated Hs2st null UB is able to undergo branching morphogenesis in the presence of exogenous sol

185 Failure in normal epithelial branching morphogenesis in the TbetaRII(Delta/Delta) lun

186 Modeling of branching morphogenesis in vitro defined specific defect

187 last growth factor-2 (FGF2) to model mammary branching morphogenesis in vitro.

188 esion kinase (FAK) and promote FAK-dependent branching morphogenesis in vitro.

189 the contribution of ILK-p38MAPK signaling to branching morphogenesis in vivo is not defined.

190 ed Fgf10 expression is not required for lung branching morphogenesis in vivo.

191 report that Btbd7 is a crucial regulator of branching morphogenesis in vivo.

192 establish a model for post-pubertal mammary branching morphogenesis in which position-dependent, lin

193 vel findings regarding pyrethroid effects on branching morphogenesis indicate these compounds may act

194 nctions including ureteric bud formation and branching morphogenesis, indicating that RA-receptor sig

195 Here we report that mammary branching morphogenesis induced by transforming growth f

196 butyl Amiloride (MIA) dramatically disrupted branching morphogenesis, induced extensive proliferation

197 Branching morphogenesis is a complex biological process

198 Branching morphogenesis is a fundamental program for tis

199 Lung branching morphogenesis is a highly orchestrated process

200 Branching morphogenesis is a molecularly conserved mecha

201 understood, at the cellular level, how renal branching morphogenesis is achieved or how Ret signaling

202 an in specific growth zones, suggesting that branching morphogenesis is achieved primarily by remodel

203 g of the epithelial basement membrane during branching morphogenesis is also essential to promote mat

204 Prostatic branching morphogenesis is an intricate event requiring

205 Branching morphogenesis is essential for the formation o

206 Lp) embryos, subsequent in vivo and in vitro branching morphogenesis is impaired.

207 We demonstrate that early UB branching morphogenesis is not primarily modulated by fa

208 Branching morphogenesis is one of the earliest events es

209 Mammary branching morphogenesis is regulated by receptor tyrosin

210 xplant culture model in vitro show that lung branching morphogenesis is sensitive to [Ca(2+)](o), bei

211 ormation during submandibular salivary gland branching morphogenesis is the critical step initiating

212 Branching morphogenesis is the developmental program tha

213 Currently, branching morphogenesis is thought to depend on the mobi

214 logical processes such as cell migration and branching morphogenesis, little is known about how these

215 o understand mouse submandibular gland (SMG) branching morphogenesis, little is known about SMG cell

216 During branching morphogenesis, new branches form by "budding"

217 The first round of branching morphogenesis occurs during embryogenesis, and

218 enchymal cross-talk are critical to ensuring branching morphogenesis occurs properly.

219 ns indicated their involvement in apoptosis, branching morphogenesis of axons, cortical neurons, and

220 ed changes in polyamine homeostasis affected branching morphogenesis of cultured murine embryonic kid

221 Branching morphogenesis of developing organs requires co

222 Branching morphogenesis of epithelia is an important mec

223 nisms driving the formation, elongation, and branching morphogenesis of epithelial tubes during devel

224 We have shown that branching morphogenesis of mammary ductal structures req

225 hanical and biochemical signaling to control branching morphogenesis of mammary epithelial cells.

226 E47 can promote collective migration during branching morphogenesis of mammary epithelial tissues th

227 ranscription factors and the EMT proteome in branching morphogenesis of mammary epithelial tissues us

228 (HS)-binding growth factor, is required for branching morphogenesis of mouse submandibular glands (S

229 Genetic ablation of Btbd7 in mice disrupts branching morphogenesis of salivary gland, lung and kidn

230 ronectin (Fn) plays an important part in the branching morphogenesis of salivary gland, lung, and kid

231 Branching morphogenesis of the epithelial ureteric bud f

232 djacent epithelial progenitor cells to alter branching morphogenesis of the epithelium.

233 These results provide new insights into branching morphogenesis of the intrahepatic biliary netw

234 In support of this notion, branching morphogenesis of the isolated UB was found to

235 We propose that Adamts16 is involved in branching morphogenesis of the kidneys in mice.

236 ostnatal development, Cripto-1 regulates the branching morphogenesis of the mouse mammary gland and e

237 We have shown previously that during branching morphogenesis of the mouse prostate gland, Bon

238 s that plays an essential role in regulating branching morphogenesis of the ocular glands.

239 The kidney collecting system develops from branching morphogenesis of the ureteric bud (UB).

240 phin for cell adhesion, gene activation, and branching morphogenesis onto the inactive syntaxin-1a te

241 l cells of the developing lung did not alter branching morphogenesis or early mesenchymal differentia

242 deletion of Foxm1 did not alter lung growth, branching morphogenesis, or epithelial proliferation but

243 enitor cell expansion and migration known as branching morphogenesis, or tubulogenesis, which proceed

244 date the role of variable HS sulfation in UB branching morphogenesis, particularly the role of 6-O su

245 Epithelial deletion of Wls disrupted lung branching morphogenesis, peripheral lung development and

246 Deletion at E10.5 resulted in a severe branching morphogenesis phenotype.

247 FGF signaling is a central regulator of branching morphogenesis processes, such as angiogenesis

248 or MMPs described here may not be limited to branching morphogenesis processes.

249 kidneys with HDACi impairs the ureteric bud branching morphogenesis program and provokes growth arre

250 Here we show that an epithelial branching morphogenesis program antagonizes alveolar dif

251 ther, the expression of genes comprising the branching morphogenesis program, such as PRDX4, SLC43A1,

252 A first wave of branching morphogenesis progresses throughout embryonic

253 suggest that S100A4-mediated effects during branching morphogenesis provide a plausible mechanism fo

254 elial cells caused retardation of early lung branching morphogenesis, reduced cell proliferation, and

255 stem cells that participate in mammary gland branching morphogenesis remain contested.

256 Branching morphogenesis requires the coordinated interpl

257 Tissue branching morphogenesis requires the hierarchical organi

258 and found it severely disrupted with reduced branching morphogenesis, resulting in fewer epithelial s

259 We observed that branching morphogenesis results from the active motility

260 architecture of these glands is generated by branching morphogenesis, revealed by recent research to

261 Branching morphogenesis sculpts the airway epithelium of

262 he lung epithelium led to a striking halt in branching morphogenesis shortly after secondary branch f

263 , and Egf family ligands stimulate embryonic branching morphogenesis, suggesting that these pathways

264 creased Hedgehog [15, 16] signaling decrease branching morphogenesis, suggesting that Wnt and Hedgeho

265 -) mice have more severe defects in ureteric branching morphogenesis than previously reported, includ

266 the ureteric bud (UB) lineage causes loss of branching morphogenesis that is rescued by loss of one c

267 he insect respiratory system, to investigate branching morphogenesis that occurs at the single cell l

268 ility and invasiveness are essential for the branching morphogenesis that occurs during development o

269 how that transmural pressure controls airway branching morphogenesis, the frequency of airway smooth

270 During the process of branching morphogenesis, the mammary gland undergoes dis

271 Branching morphogenesis, the process by which cells or t

272 oordinated gene network controls trophoblast branching morphogenesis, thereby facilitating developmen

273 basement membrane is assumed to occur during branching morphogenesis to accommodate epithelial growth

274 Many mammalian organs undergo branching morphogenesis to create highly arborized struc

275 and development, an epithelial bud undergoes branching morphogenesis to expand into a continuous tree

276 ounded by mesenchyme, and it undergoes rapid branching morphogenesis to form a complex secretory orga

277 ric bud is an epithelial tube that undergoes branching morphogenesis to form the renal collecting sys

278 Many embryonic organs undergo branching morphogenesis to maximize their functional epi

279 basement membrane remodeling is required for branching morphogenesis to regulate cell-matrix and cell

280 Although neither proteinase is required for branching morphogenesis, transcriptome profiling reveals

281 then established a 3D cell culture model of branching morphogenesis using primary pancreatic duct ce

282 sms that underlie critical processes such as branching morphogenesis, vascular development, and the d

283 GFR-mediated epithelial proliferation during branching morphogenesis via a Vldlr-dependent mechanism.

284 In addition, HGF-induced mammary epithelial branching morphogenesis was significantly reduced in Eph

285 ferentiate into tubule secretory cells while branching morphogenesis was unaffected.

286 sion atlas to search for novel regulators of branching morphogenesis, we found a substantial reductio

287 t separately model distinct stages of kidney branching morphogenesis, we found that the Hs2st(-/-) UB

288 bmandibular glands (SMGs) as models to study branching morphogenesis, we have identified new vectors

289 genes regulating early tissue patterning and branching morphogenesis were differentially regulated.

290 expression patterns and possible function in branching morphogenesis were investigated.

291 yoepithelial, and stromal cells during early branching morphogenesis when epithelial ducts extend int

292 l lung requires two developmental processes: branching morphogenesis, which builds a tree-like tubula

293 tecture of the mammary gland is generated by branching morphogenesis, which is regulated by many sign

294 development, including several mediators of branching morphogenesis, which subsequently leads to kid

295 al cells cultured ex vivo exhibited enhanced branching morphogenesis, which was reduced upon MAPK inh

296 e suppressive effects of high [Ca(2+)](o) on branching morphogenesis while both phospholipase C and P

297 1 to promote cholangiocyte specification and branching morphogenesis while concomitantly suppressing

298 Salivary glands are formed by branching morphogenesis with epithelial progenitors form

299 g that controls primary branch formation and branching morphogenesis within the kidney.

300 Branching morphogenesis within the peripubertal mouse ma