ライフサイエンスコーパス: breach

1 of relationship experience before the trust breach.

2 tect the epithelial barrier from C. albicans breach.

3 2 containment facility, without any apparent breach.

4 bition of S1P1 function led to transient BBB breach.

5 play deposit are found further away from the breach.

6 of mucositis onset, inducing mucosal barrier breach.

7 in cases where the fetal-maternal barrier is breached.

8 hich international humanitarian law is being breached.

9 al infections when the epithelial barrier is breached.

10 acental defenses and how this barrier can be breached.

11 the preparation of large acenes has now been breached.

12 neuropathological states in which the BBB is breached.

13 ection at any site where the skin barrier is breached.

14 of commensal bacteria when gut barriers are breached.

15 to the point in LH1 that appears most easily breached.

16 ificant outburst flood hazards if the dam is breached.

17 ts an impenetrable barrier unless surgically breached.

18 ved out of the neural boundary through these breaches.

19 t mix with seawater entering from the crater breaches.

20 ered host molecules, or signs of compartment breaches.

21 gle platelets to neutrophil-induced vascular breaches.

22 scour and deposition occurred near the levee breaches.

23 ption factor that promotes basement membrane breaching.

24 ool erosion by waterfalls and subsequent dam breaching.

25 Following the breach, a large protrusion forms to clear a path for tis

26 that eventually overtopped, and subsequently breached, a levee in Joso City, causing destructive floo

27 oskeletal collapse, which allows H. somni to breach alveolar barriers and cause septicemia.

28 o a stable invasive process that expands the breach and crosses into the vulval tissue.

29 ndings suggest that nicotinamide reduces BBB breach and neuronal cell loss acutely following injury a

30 coordinate distinct signaling activities to breach and pass through this dense extracellular matrix

31 ly enriches at the site of basement membrane breach and that activation by UNC-6 (netrin) directs foc

32 hils in turn promote the blood-brain barrier breach and together with T cells lead to further inflamm

33 d canals upstream of a bedrock ridge that is breached and bordered by a system of concentrated channe

34 in kinetic proofreading, this barrier can be breached and greater sharpness achieved.

35 ance for nucleic acid-containing antigens is breached and systemic autoimmunity ensues.

36 ge rate (k(int)) is increased, this limit is breached and the rate begins to rise again.

37 eal infections occur secondary to epithelial breaches and represent a major cause of vision impairmen

38 on-related mitochondrial swelling results in breaching and disruption of the OMM.

39 ctions are destabilized, barrier function is breached, and flow is perturbed, resulting in abnormal v

40 t how these organs sense that equilibrium is breached, and how they cease changing when homeostasis i

41 ponds to microbial stimuli once barriers are breached, and mediates protection against DSS-induced co

42 n, the intestinal epithelial cell barrier is breached, and the detection of microbial molecules in th

43 ary to rapidly evolving technologies, safety breaches, and variable, nonstandardized structures and p

44 Host range breaches are limited by incompatibilities between avian

45 Human cells must breach at least two distinct senescence barriers to perm

46 of Sle2 on the C57BL/6 background profoundly breached B cell tolerance to DNA, apparently by thwartin

47 ronic data files for risk of confidentiality breach based on unique combinations of key variables.

48 Invasive cells use small invadopodia to breach basement membrane (BM), a dense matrix that encas

49 wing of F-actin dynamics and an inability to breach basement membrane.

50 , we identify F-actin-based invadopodia that breach basement membrane.

51 egeli et al. (2017) identify a mechanism for breaching basement membranes.

52 dritic cells to the site of damage through a breached blood-brain barrier or via brain lymphatics.

53 escribe how metastatic prostate cancer cells breach BMEC monolayers in a step-wise fashion under phys

54 Physical damage was induced by breaching Bruch's membrane and inducing vascular endothe

55 vulval cells facilitate enlargement of this breach by promoting BM movement.

56 tation once the cotyledonary cell walls were breached by bacterial degradation.

57 rability threshold that could more easily be breached by inflammation during critical periods of brai

58 inflammation when the epithelial barrier is breached by physical trauma or pathogenic microbes.

59 derstanding of morphogenetic controls may be breached by powerful techniques from the computational s

60 e disease of the skin, these barriers can be breached by the cationic antimicrobial peptide LL37.

61 pithelium is the first physiological barrier breached by the Gram-positive facultative pathogen Liste

62 te distinct aqueous compartments, but can be breached by transient hydrophilic pores.

63 onment mediate rapid detection of epithelial breaches by leukocytes in larval zebrafish tail fins.

64 to measure penetration depth and area of the breach caused by microneedle penetration following stain

65 The mechanism by which papillomaviruses breach cellular membranes to deliver their genomic cargo

66 g).sHEL BCR-transgenic mice, Sle2(z) did not breach central tolerance, but it led to heightened expre

67 This is consistent with the breach cluster residues being well conserved across the

68 e and local health agencies, and the duty to breach confidentiality to warn of imminent harm has been

69 It was breached during rapid cerebral cortical expansion at E13

70 Identified infection control breaches during AMBG included shared use of fingerstick

71 Breaching endothelial cells (ECs) is a decisive step in

72 ems: while decision making after early trust breaches engages structures of a controlled social cogni

73 al cortex, decision making after later trust breaches engages structures of an automatic social cogni

74 When unanticipated insults breach epithelial barriers, dormant programmes of tissue

75 er of the human oropharynx that occasionally breaches epithelial barriers to cause invasive diseases.

76 sm that prepares the host in case a pathogen breaches epithelial defenses to invade internal tissues.

77 pr1 knockout mice (S1pr1(iECKO) ) showed BBB breach for small-molecular-mass fluorescence tracers (<3

78 hreshold value (60 nM for SHC1) that must be breached for success in immunoprecipitation.

79 eater relationship experience before a trust breach fosters trust recovery.

80 rst thought one might consider the effect to breach fundamental thermodynamic laws, but we show that

81 es grouped into three clusters, known as the breach, gate, and shutter.

82 our data suggest that LT, via Bub1 binding, breaches genome integrity mechanisms, leading to DNA dam

83 Such a breach gives pathogens access to the enterocyte, leading

84 ms, likely leading to reduced barrier island breaching, greater bay enclosure, and fine-grained sedim

85 his provides a mechanism for strain G9241 to breach host barrier defenses and promote bacterial growt

86 tive bacterial type-3 secretion systems that breach immune barriers and deliver virulence factors int

87 ects with a single TACI mutation displayed a breached immune tolerance and secreted antinuclear antib

88 Importantly, experimentally breaching immunological tolerance in wild-type mice also

89 pH, Al, and Fe during an uncontrolled river breach in 2011, however, incorporating sediment biogeoch

90 We now provide evidence that the breach in allelic exclusion associated with Emu deletion

91 in NZB/W mice, it does not correct the major breach in B cell tolerance that occurs at the GC checkpo

92 This breach in CNS immune privilege allows undeterred traffic

93 sults in a paucity of T(R) cells and a fatal breach in immunological tolerance, causing highly aggres

94 blocking expression of autoimmunity where a breach in peripheral tolerance is suspected.

95 by the blood-brain barrier (BBB); however, a breach in the barrier's integrity exposes neurons to pot

96 This causes a focal breach in the BBB.

97 cognition when they access the CNS through a breach in the blood-brain barrier (BBB) triggered by lip

98 immunoglobulin G revealed a kainate-induced breach in the blood-brain barrier.

99 rane defects, which may ultimately lead to a breach in the cell membrane and cell death.

100 -borne pathogens, their increase following a breach in the gut epithelial barrier would be protective

101 face between the environment and the body: a breach in the integrity of this interface can lead to th

102 There was a breach in the normal outline of the lower sternum indica

103 the immunologically privileged CNS through a breach in the relatively impermeable blood-brain barrier

104 ange in cell shape, and is associated with a breach in the underlying basal lamina.

105 ted division septum, generating a mechanical breach in the wall.

106 anger signal alerting the immune system of a breach in tissue integrity.

107 In addition, B-cell tolerance was further breached in AID-deficient patients as illustrated by the

108 e further demonstrate that B cell anergy was breached in IRF8-deficient mice.

109 We tested the hypothesis that breaches in basement membrane and the underlying glia li

110 We tested the hypothesis that breaches in basement membrane and the underlying glia li

111 Prolonged breaches in epithelial barrier function result in inflam

112 tigations identified aerosol release through breaches in heater-cooler tanks.

113 Review of this process identified breaches in mixing, filtration, and sterility testing pr

114 can cause systemic disease in patients with breaches in mucosal integrity, indwelling catheters, and

115 groups with LTP-A, with potential integrity breaches in patients with LTP-A that might explain their

116 of the cerebral cortex in the knockout mice, breaches in pial basement membrane allowed emigration of

117 We hypothesize that breaches in pial basement membrane disrupt the neural-me

118 We hope that breaches in standard infection control will become vanis

119 idal activity against P. acnes, and complete breaches in the bacterial cell envelope were observed.

120 de by inserting invasive pseudopodia through breaches in the basement membrane (BM), a specialized ba

121 and hypoplasia are also associated with the breaches in the BM and abnormal Bergmann glial networks

122 ytic enzymes are regulated to prevent lethal breaches in the cell wall.

123 ndividing GEPs, to microorganisms traversing breaches in the GEP plasma cell membrane.

124 presenting cells and T cells must respond to breaches in the mucosal barrier by activating TLR-depend

125 EKK4(-/-) mice developed PVH associated with breaches in the neuroependymal lining which were largely

126 egulated to prevent the generation of lethal breaches in the PG matrix.

127 model of muscle-eye-brain disease, caused by breaches in the pial basement membrane.

128 hat the leading causal events are likely the breaches in the pial BM.

129 erficial cell layers are exfoliated, leaving breaches in the protective MUC16 glycocalyx.

130 Breaches in the skin barrier initiate an inflammatory im

131 e lapses in manufacturing quality control or breaches in the supply chain allow substandard medicines

132 ol over these enzymes is critical to prevent breaches in wall integrity that can cause cell lysis.

133 When the barriers are breached, infection can result in rapid tissue destructi

134 Alcohol causes microbiota dysbiosis and breaches intestinal integrity, resulting in liver inflam

135 orter and stronger intermolecular bonds that breach into the range of extremely stretched single bond

136 In general, membrane breach is achieved via the highly regulated spatiotempor

137 skin provides protection when the barrier is breached is not well understood.

138 duce their attachment to BM, influence these breaches is unknown.

139 mpenetrable, and mechanisms by which viruses breach it are becoming clearer.

140 ts infancy, and both how and where T. gondii breaches it are unknown.

141 en's strategy to enter the host organism and breach its immune defenses often involves interactions b

142 Separated parasites leave the erythrocyte by breaching its membrane, weakened by putative digestion o

143 ive erosional features are found next to the breached levee, while depositional features, such as a s

144 etation between the river and the main levee breach likely prevented widespread deposition, localized

145 , fetal cytotrophoblasts invade the decidua, breach maternal blood vessels, and form heterotypic cont

146 ontinued until crystals outgrew cell size to breach membrane integrity.

147 Nineteen companies were ruled in breach more than once, and ten companies were ruled in b

148 Another breach mutant, H191A, shows perturbed collagen release c

149 y of the tested mutants are silent; however, breach mutants H197A and H198A show binding but no appar

150 ature of the relationship in which the trust breach occurs.

151 Acute breach of anergy by compromise of either of these pathwa

152 Breach of B cell tolerance is central to the pathogenesi

153 particular T cell subset is involved in the breach of B cell tolerance revealed increased Th17 cells

154 ter neuropeptide Y (NPY) actively promotes a breach of BM vascular sinusoidal portals, thereby augmen

155 In type 1 diabetes, the breach of central and peripheral tolerance results in au

156 hat can quantify the risk of confidentiality breach of electronic health databases, including reident

157 e European metropolitan areas are already in breach of EU safety limits for NO2, this phenomenon does

158 In addition to being a breach of human rights, intimate partner violence is ass

159 inducible ectopic lymphoid tissue formation, breach of humoral self-tolerance, and salivary hypofunct

160 limiting membrane (ILM) (P = .004); (3) the breach of ILM (P = .004); (4) the breach of posterior hy

161 ch as citrullination have been linked to the breach of immune tolerance and clinical autoimmunity.

162 safety of the performance of colleagues is a breach of medicine's fiduciary responsibility to the pub

163 hat is hypothesized to facilitate neutrophil breach of mucosal barriers.

164 te the underlying mechanisms of neutrophilic breach of mucosal barriers.

165 dies of specific system deficiencies such as breach of physical or hydraulic pipe integrity and lack

166 ship, and 43.1% consider that reporting is a breach of physician-patient confidentiality.

167 ); (3) the breach of ILM (P = .004); (4) the breach of posterior hyaloid (P = .0005); (5) hyperreflec

168 organs, cells and molecules involved in the breach of self-tolerance have been partially defined in

169 ed by low probability cues, which signaled a breach of spatial expectation, independently of whether

170 e, deficient IL-2 production could promote a breach of T cell tolerance that results in autoantibody

171 Moreover, the mechanical forces induce a breach of the basement membrane barrier at the distal po

172 d CNS inflammation with a concomitant lethal breach of the BBB.

173 d activator of transcription (Stat) pathway, breach of the blood-brain barrier (BBB), and virus-induc

174 IgG immunostaining revealed a KA-induced breach of the blood-brain barrier in animals of both age

175 olase in S. mutans attachment, clearance, or breach of the bloodstream barrier.

176 Infection of mice with C. rodentium causes breach of the colonic epithelial barrier, a vigorous Th1

177 A breach of the epithelial barrier of the GI tract can res

178 d seronegative subjects suggest that a viral breach of the exposure site is more common than current

179 balanced intestinal homeostasis results in a breach of the gut barrier and subsequent microbial trans

180 Infection of mice with C. rodentium causes a breach of the intestinal epithelial barrier, leading to

181 The emergence of MCR-1 heralds the breach of the last group of antibiotics, polymyxins, by

182 ong spinal motor root axons and an immediate breach of the MEP by OPCs.

183 mucosa-associated microbiota, and subsequent breach of the mucosal barrier facilitates progression of

184 Neutrophil breach of the mucosal surface is a common pathological c

185 degranulation of human CLs, resulting in the breach of the target cell membrane by perforin within 65

186 study, we explored the possibility that this breach of tolerance reflects loss of B cell anergy.

187 y plasmacytoid DCs (pDCs) in the spontaneous breach of tolerance to arthritis-related self proteins,

188 functional impairment, rather than an overt breach of tolerance, is a critical feature that governs

189 mmatory function in the context of articular breach of tolerance.

190 required to both establish and maintain the breach of tolerance.

191 Breaches of basement membranes coincide with the patholo

192 ult in increased plant uptake, with possible breaches of food or feed safety standards.

193 However, breaches of honesty are pervasive and cause significant

194 Breaches of local innate immune defenses provide critica

195 Breaches of OMM integrity result in the release of cytoc

196 t this region is preferentially sensitive to breaches of taste expectation.

197 Despite the importance of breaches of taste identity expectation for survival, its

198 ces so that measures can be taken to address breaches of these quality standards using the polluter p

199 The authors report that, following breaches of trust, oxytocin facilitates prosocial behavi

200 ations support the megaflood model, in which breaching of a rock dam at the Dover Strait instigated c

201 Lake spillover is inferred to have caused breaching of a rock ridge at the Dover Strait, although

202 By this interaction, MUC4 promotes breaching of basement membrane (BM) integrity, and sprea

203 n to hepatitis, HCV infection may also cause breaching of immune tolerance, leading to autoimmune dis

204 f tumour cells into the circulation, and the breaching of lung capillaries by circulating tumour cell

205 Breaching of the barrier causes mobilization of immune c

206 he pathogenesis of K. kingae disease include breaching of the epithelial barrier and destruction of t

207 d with catastrophic flooding indicates final breaching of the Strait by high-magnitude flows.

208 oplanin exposed to the vasculature following breaching of the vessel wall.

209 ke disappearance suggests (i) that thaw and "breaching" of permafrost is driving the observed losses,

210 absence of other pathologies and without BBB breach or significant inflammation.

211 These data demonstrate that breaching peripheral tolerance permits a cross-reactive

212 t neuroserpin has greater flexibility in the breach region and in beta-strand 1C compared with alpha(

213 between their structures and dynamics in the breach region at the top of beta-sheet A, which is close

214 d solvent exposure of buried residues in the breach region in Z, as well as polymerization via domain

215 IBD), the line of defense provided by IEC is breached, resulting in uncontrolled immune responses.

216 the retina as an inevitable consequence of a breached retina.

217 lain why Sle3-bearing DCs may be superior at breaching self tolerance.

218 ing that additional factors are required for breaching self-tolerance in the setting of lymphopenia.

219 NC-6(netrin)/UNC-40(DCC) signaling at the BM breach site directs exocytosis of lysosomes using the ex

220 e, we present an overview of genetic privacy breaching strategies.

221 ode are often described as a series of small breaches that grow over time.

222 t a general mechanism used by tumor cells to breach the basement membrane and for invasive migration

223 ired for the AC to generate protrusions that breach the basement membrane.

224 he endothelial junctions, could additionally breach the BBB via the transcellular route.

225 neuronal damage and memory deficit, if they breach the BBB, and that the Abs exist within patients'

226 tion, and (iii) how might T(H)17 lymphocytes breach the BBB.

227 ili (T4P) to adhere to endothelial cells and breach the blood brain barrier, causing cause fatal meni

228 blood-borne bacteria must interact with and breach the blood-brain barrier (BBB) that is composed of

229 o mimic the inflammatory pathology of MS and breach the blood-brain barrier.

230 ection, they populate the blood; later, they breach the blood-brain barrier.

231 ymph nodes (LNs) capture microorganisms that breach the body's external barriers and enter draining l

232 at cells use an IFT-independent mechanism to breach the diffusion barrier at the flagellar base.

233 ryos may fail to implant although many first breach the endometrial epithelium and embed in the decid

234 ised to vigorously respond to pathogens that breach the epithelial barrier.

235 acks ER protein quality control machinery to breach the ER membrane and access the cytosol, a decisiv

236 sive cancers use pericellular proteolysis to breach the extracellular matrix and basement membrane ba

237 ch lionfish were provided the opportunity to breach the Florida Current.

238 eactive oxygen species (ROS) that ultimately breach the glial limitans and promote spread of the inju

239 Invasive pathogens must breach the glycan layer before initiating infection.

240 In normal physiology, luminal microbes breach the intestinal epithelial barrier and gain access

241 from internal myofibres that in rare events breach the juvenile ventricular wall, and then expand ov

242 h and inflammatory cascades in host cells to breach the keratinocyte barrier for dissemination into d

243 ctures called appressoria, which are used to breach the leaf cuticle and allow development of intrace

244 for protrusion of a rigid penetration peg to breach the leaf surface.

245 In its severest form, choroidal neovessels breach the macular Bruch's membrane, an extracellular ma

246 weapons often used by bacterial pathogens to breach the membrane barrier of target cells.

247 to accumulation of intestinal contents that breach the mucosal barrier of the bowel wall, resulting

248 The ability to breach the optical diffraction limit to image living cel

249 and measure the dimensions of channels that breach the peptidoglycan between vegetative cells and be

250 pathogens associated with congenital disease breach the placental barrier to transit vertically durin

251 r findings indicate that XynB contributes to breach the plant cell wall barrier, providing nutrients

252 Goodpasture antibodies only breach the quaternary structure of M-hexamers, unmasking

253 lated macular degeneration (AMD) capillaries breach the RPE barrier.

254 the nanoparticles within the polymer matrix, breach the skin's stratum corneum barrier and dissolve u

255 ct a small volume of physiological saline to breach the skin, and the back-drivability of the actuato

256 In crucifers, the pollen tube must breach the stigma surface and burrow through the extrace

257 e tephra shows that subglacial volcanism can breach the surface of the ice sheet and may pose a great

258 Severe or chronic/prolonged UPR can breach the threshold for survival and lead to cell death

259 ell called an appressorium, which is used to breach the tough outer cuticle of a rice leaf, enabling

260 the decidua, invasive cytotrophoblasts that breach the uterine vasculature and villous cytotrophobla

261 re a small number of internal cardiomyocytes breach the ventricular wall and expand upon its surface.

262 icule muscle contractions during attempts to breach the vulva.

263 l intestinal villi, and flagellated bacteria breached the colonic mucosal barrier.

264 It has breached the public consciousness and is being asked for

265 t to develop when Mycobacterium tuberculosis breaches the blood-brain barrier (BBB), which is compose

266 infection cell called an appressorium, which breaches the cuticle of the rice leaf, allowing the fung

267 d that a hyperfilamentous C. albicans strain breaches the epithelial barrier more frequently and caus

268 rapid dissemination of the pathogen after it breaches the gut.

269 pectively, would restrict the probability of breaching the 55-mm limit at rescreening to below 1%.

270 riggering restored BCR functionality, likely breaching the anergic state, and this was accompanied by

271 has been viewed as a barrier to physicians' breaching the confidentiality of personal genetic inform

272 he opening of large-scale apertures, thereby breaching the endothelium barrier.

273 at mortality is a consequence of C. albicans breaching the epithelial barrier and invading surroundin

274 fic sperm, invading the ovary, and sometimes breaching the gonad to infiltrate other tissues.

275 After breaching the host surface, the fungus establishes an in

276 ps on the damaged tryptophan sidechain, thus breaching the integrity of nearby dry center regions for

277 rebound evulsion, traumatizing the globe and breaching the nerve posteriorly.

278 hepatocytes, and deliver DNA to the cytosol, breaching the nucleus remains the last major barrier to

279 port fully folded protein substrates without breaching the permeability barrier of the membrane.

280 d were used as exit points by neutrophils in breaching the venular wall.

281 ategy and must employ alternative methods to breach their host cell's delimiting membrane.

282 Therefore, unique approaches to breaching these barriers are needed.

283 deployed by both hosts and pathogens alike, breach this barrier to lyse target cells.

284 e, but Palladini and colleagues' study helps breach this gap.

285 I secretion system of Pseudomonas aeruginosa breaches this barrier to deliver two effector proteins,

286 Proteolysis selectively breaches this tolerance by generating autoimmunogenic al

287 e than once, and ten companies were ruled in breach three or more times over the 10-y period.

288 tting occurs when episodic natural disasters breach thresholds with little or no warning, resulting i

289 on can be used as a mechanism to regulate BM breaches, thus controlling the exchange of cells between

290 contexts in which migrating cells appear to breach tissue barriers, they are actually exploiting exi

291 me-derived membrane structure specialized to breach tissue barriers.

292 tracts form a barrier that many viruses must breach to infect their hosts.

293 of autoreactive IgGs from B cells that have breached tolerance checkpoints and entered the Ab-formin

294 acement was unsuccessful (abdominal wall not breached), two patients were ultimately not cooled, and

295 ream from Los Alamos National Laboratory was breached underground and was the most likely source of t

296 ferentiate, assume an endothelial phenotype, breach uterine blood vessels and form a hybrid vasculatu

297 y, is viewed as a shifting balance between a breach versus establishment of tolerance to tumor or sel

298 Prostate cancer cell breaching was regulated by Rac1 and Rap1 GTPases and, no

299 hat were unattributable to infection control breaches were identified at a health care facility.

300 iology, they nevertheless pose the threat of breach with ensuing pathologies.