ライフサイエンスコーパス: break

1 of copious rainfall and quiescent phases of 'break'.

2 th higher levels of aggression (but not rule-breaking).

3 interstrand cross-link adjacent to a strand break.

4 es are required to introduce a double strand break.

5 n be rescued by tethering the donor near the break.

6 ps and hairpins within 30 nucleotides of the break.

7 eukaryotes utilize RNA to repair chromosome breaks.

8 the final number of simulated double strand breaks.

9 integrity with the potential to cause strand breaks.

10 he repair and signaling of DNA double strand breaks.

11 efficient RAD51 loading at DNA double-strand breaks.

12 th further possible formation of the retinal breaks.

13 eved even with dose reductions and treatment breaks.

14 aling and accumulation of protein-linked DNA breaks.

15 he induction of DNA single- or double-strand breaks.

16 tranded DNA lesions into double-stranded DNA breaks.

17 lication elongation and causes double-strand breaks.

18 coordinate the repair of double-stranded DNA breaks.

19 ls, which are converted to DNA double-strand breaks.

20 H2O2 breakdown; and 4) result in DNA strand breaks.

21 ken filament depends on how the filament was broken.

22 and realistic human exposure is effectively broken.

23 disease, religious texts allow fasting to be broken.

24 come in systems where Lorentz reciprocity is broken.

25 not equivalent because of inversion symmetry breaking.

26 bryos is responsible for left-right symmetry breaking.

27 que information about the energy required to break a LBHB.

28 vinylene] (MDMO-PPV), polystyrene (PS), thus breaking a new ground on the controlled preparation of p

29 Each reaction breaks a C-C bond and results in net loss of hydride, vi

30 d to illuminate atomic-level details of bond breaking and formation during the hydrolysis of a chemic

31 ion, cycloaddition, annulation, and diverse "breaking and mending" approaches.

32 ured the mechanical work produced during the breaking and rebinding to determine a free-energy differ

33 -printed muSPE devices enabled fast emulsion breaking and solvent deasphalting of petroleum, yielding

34 ive scale selection controls mirror-symmetry breaking and the emergence of a 3D inverse cascade.

35 leads to a marked increase in unrepaired Igh breaks and a significant reduction in CSR in ex vivo act

36 sferases promote repair of DNA single strand breaks and disruption of this pathway by Poly(ADP-ribose

37 troduce changes (rather than double-stranded breaks and donor templates) and offers potential improve

38 DBAN is not mutagenic but causes DNA breaks and elevates sister chromatid exchange in mammali

39 -Mlh3 can generate religatable double-strand breaks and form an active nucleoprotein complex that can

40 ain types of damage, such as double-stranded breaks and interstrand crosslinks.

41 gous recombination repairs DNA double-strand breaks and must function even on actively transcribed DN

42 cells leads to widespread DNA double-strand breaks and synthetic lethality.

43 everal intermediate nucleosomal states as it breaks and then reforms histone-DNA contacts ahead of an

44 ontacts within the replisome are continually broken and reformed.

45 duced in late 1990's but soon resistance was broken and was associated with a single recombinant bego

46 recombination, repair of double stranded DNA breaks, and integron recombination.

47 idized DNA lesions, double-strand DNA strand breaks, and pronounced susceptibility to single-strand b

48 inuous scale symmetry of a quantum system is broken, anomalies occur which may lead to quantum phase

49 t the criterion used to select direct strand break appears to have a very significant role on the fin

50 taxia-telangiectasia), and DNA double-strand breaks are crucial to the modulation of early gene expre

51 er, the conjugate acid would resist C-C bond breaking as that would lead to formation of doubly proto

52 Retinal break associated with induction of posterior vitreous de

53 thods involve the induction of double-strand breaks at endogenous loci followed by the identification

54 authors show that the smoothness assumption breaks at scales far smaller than believed and the balli

55 ecial cases, classical conservation laws are broken at the quantum level by quantum fluctuations, in

56 Upon induction of DNA breaks, ATM activation leads to a cascade of local chrom

57 Overall, results indicate that during breaks between short blocks, it is the higher-level perc

58 The association of early (skin breaks, birth-Scan 1) and late pain (skin breaks, Scans

59 These chiral active fluids break both parity and time-reversal symmetries in their

60 Symmetry is broken by motile cilia-generated asymmetric fluid flow,

61 Inaccurate repair of broken chromosomes generates structural variants that ca

62 Broken continuous scale symmetry into discrete scale sym

63 one side of the cell in response to symmetry-breaking cues.

64 of selective susceptibility to double-strand-break damage due to high transcriptional activity or, th

65 eroduplex, in which a single-strand from the broken DNA molecule pairs with a strand derived from an

66 RNase H-deficient cells, while double-strand breaks do.

67 ng timescales, these long-range correlations break down during non-REM sleep.

68 iosis, and the absence of these peptides can break down the mutualism.

69 ome-mediated RI would be transient and would break down under dietary variation.

70 ently retrieved by, particular stimuli, thus breaking down the traditional dichotomy between top-down

71 me uniquely enriched in the hippocampus that breaks down cyclic AMP and cyclic GMP.

72 uccess of fMRI, though functional smoothness breaks down in the later network layers.

73 w the distinction between the two mechanisms breaks down near its border due to the differing time sc

74 Activated protein C (APC) breaks down the complex that produces thrombin by proteo

75 bond, the liberated hemiacetal spontaneously breaks down, leading to separation of the fluorophore an

76 When this protection breaks down, superficial and invasive fungal infections

77 n parameter regimes where this approximation breaks down.

78 rows invasively through the endosperm, which breaks down.

79 signs where the approximation for meta-atoms breaks down.

80 Additionally, the carbonaceous nature of NCS broke down by human myeloperoxidase and horseradish pero

81 The extra-casein protein sample matrix broke down more slowly than the others because the casei

82 effects of interventions on lifespan can be broken down into changes in the frequency and/or timing

83 ning chemically different side chains, whose break-down products are involved in stress response agai

84 t extensive resection of a DNA double-strand break (DSB) by a multisubunit helicase-nuclease machine

85 n, regulating cessation of DNA double-strand break (DSB) formation following crossover designation, a

86 ffect of contrast agent on DNA double-strand-break (DSB) formation in patients undergoing magnetic re

87 After DNA double-strand break (DSB) generation, Cdc14 is transiently released fr

88 A DNA double-strand break (DSB) is the most critical type of genotoxic stres

89 of the HR pathway to complete double-strand break (DSB) repair by about 50%.

90 RIF1 foci, suggesting that DNA double-strand break (DSB) repair by homologous recombination (HR) was

91 Pathway choice within DNA double-strand break (DSB) repair is a tightly regulated process to mai

92 HEJ) is the most prominent DNA double strand break (DSB) repair pathway in mammalian cells.

93 us recombination (HR) is a DNA double-strand break (DSB) repair pathway that protects the genome from

94 ning (NHEJ) is the predominant double-strand break (DSB) repair pathway throughout the cell cycle and

95 the expression of several DNA double-strand break (DSB) repair proteins and formation of repair comp

96 Improper DNA double-strand break (DSB) repair results in complex genomic rearrangem

97 us recombination (HR)-mediated double-strand break (DSB) repair, which is mediated through its abilit

98 ed to the progerin-induced DNA double-strand break (DSB) sites, blocking DSB repair, which led to DSB

99 spatio-mechanical processes of double-strand break (DSB)-repair, especially the auxiliary factor(s) t

100 mosomal locus containing a DNA double-strand break (DSB).

101 and catalyzes excision through double strand breaks (DSB) and the joining of newly excised transposon

102 stered DNA lesions (OCDL), DNA double-strand breaks (DSB), apoptosis, and the local and systemic immu

103 ccurrence of single-strand and double-strand breaks (DSB).

104 ive oxygen species-induced DNA double-strand breaks (DSBs) and were modestly sensitive to poly-ADP-ri

105 on, a subset of programmed DNA double-strand breaks (DSBs) are repaired as crossovers, with the remai

106 n the examination of how DNA double-stranded breaks (DSBs) are repaired, with many components of the

107 mplicated in the repair of DNA double-strand breaks (DSBs) by homologous recombination (HR), the mole

108 biochemical evidence that DNA double-strand breaks (DSBs) can be directly generated by Top1 at sites

109 l and repair efficiency of DNA double-strand breaks (DSBs) caused by exposure to gamma radiation acro

110 aging agent that induces DNA double-stranded breaks (DSBs) does not affect the interaction between DD

111 primary repair pathway for DNA double strand breaks (DSBs) in humans.

112 cs through the generation of double stranded breaks (DSBs) in murine macrophage genomic DNA.

113 re modified in response to DNA double strand breaks (DSBs) in vivo by the ARTs Adprt1a and Adprt2.

114 ption and genome stability.DNA double-strand breaks (DSBs) induced by topoisomerase II (TOP2) are rej

115 Repair of DNA double strand breaks (DSBs) is key for maintenance of genome integrity

116 Resection of double-strand breaks (DSBs) plays a critical role in their detection a

117 DNA double-strand breaks (DSBs) prevent cells from entering mitosis allowi

118 Double strand breaks (DSBs) represent highly deleterious DNA damage an

119 (RAP80) helps recruit BRCA1 to double-strand breaks (DSBs) through the scaffold protein CCDC98 (Abrax

120 on of recombination-initiating double-strand breaks (DSBs) via a feedback loop triggered by crossover

121 activity of which leads to DNA double-strand breaks (DSBs) within IgH switch (S) regions.

122 e the formation of meiotic DNA double-strand breaks (DSBs), the precursors of cross-overs.

123 11) in 5' end resection at DNA double-strand breaks (DSBs).

124 from two different chromosomal double-strand breaks (DSBs).

125 egies rely on Cas9-induced DNA double-strand breaks (DSBs).

126 origin of PHE is the peculiar time-reversal-breaking effect of an in-plane magnetic field, which ani

127 ng and moving conducting walls could make or break electrical connections in new forms of reconfigura

128 chemistry strongly modulate the bridging of broken ends by the NHEJ core complex.

129 ion of DNA damage, genome-wide double-strand breaks enriched at Ssb-binding regions and CpG islands,

130 ies required 84% more spring warming for bud break, EU ones 49% and EA ones only 1%.

131 otocatalysts participate in the bond-forming/breaking event in the transformation via a substrate-TM

132 ogress into R-gaps and then to double-strand breaks-explaining why R-tracts do not accumulate in RNas

133 pes (black, green), leaf grades (whole leaf, broken, fannings, dust) and manufacturing techniques (or

134 e that assembly of a new cap at the tip of a broken filament depends on how the filament was broken.

135 on, weekly, for 7 weeks followed by a 1-week break, followed by a cycle of 3 weeks of treatment with

136 m Hall effect and topological bulk insulator breaks for specific field intervals within the plateaus.

137 be considered to reduce the risk of retinal break formation and to prevent the central vision loss.

138 ate and an ordered HS-LS phase with symmetry breaking from monoclinic P21/n into orthorhombic P21212

139 rotein-starch matrix, roughly increasing the broken grains percentage.

140 h day [4] with those who were given a 30-min break halfway through each practice session.

141 The in-plane symmetry breaking has little apparent connection to the underlyin

142 Below 10% MC, water molecules tend to break hydrogen bonds between polymer chains and form new

143 mmunotherapy; thus, developing strategies to break immune tolerance is a high priority.

144 hat syngeneic bile duct antigens efficiently break immune tolerance of recipient mice, capturing seve

145 s therefore to design interventions that can break immunological tolerance and halt cancer progressio

146 The repair of DNA strand breaks improves, as do serum protein concentrations that

147 order oligomers to generate a double strand break in DNA.

148 types form a smooth continuum with no sharp break in properties.

149 and provide further support for a postcurium break in the actinide series.

150 lake spray aerosol (LSA) produced from wave-breaking in freshwater HABs.

151 tly greater ability to resist stress without breaking in vitro compared with actin or microtubules, a

152 er also led to 1.3-2.2 times more water main breaks in 2014-2015 compared to 2010-2013; such disrupti

153 inhibition and enhanced DNA double-stranded breaks in response to the combination.

154 arkably, we discovered unrepaired DNA strand breaks in SMCs within the human ascending aorta, which w

155 es longer at laser-induced DNA double-strand breaks in the absence of Werner syndrome (WRN) protein,

156 uitment without affecting KU dynamics at DNA breaks in vivo.

157 The symmetry of a homodimer is broken in heterodimeric reaction-center structures, such

158 e reversal and certain mirror symmetries are broken in the ordered phase.

159 ntioxidant barrier against DNA double strand breaks induced by TGFbeta expressed in the tumor microen

160 ments that subsequently reintegrate into DNA breaks induced on a heterologous chromosome.

161 oluble fraction and alters the double-strand break-induced protein complex centring 53BP1.

162 The effects of hot and cold break industrial tomato paste production steps on phenol

163 stiffness that is required by the matrix to break intercellular adhesions and initiate cell invasion

164 To begin breaking into language, infants must discern subtle stat

165 Here we introduced double-stranded DNA breaks into the nuclear genome of tobacco through induci

166 e symmetry of a scale-free quantum system is broken into a discrete scale symmetry for a critical val

167 ctural type of metal-oxygen intermediate and broken into subsections based on the metal (manganese an

168 ered cation arrangements and their interplay break inversion symmetry, while informatics tools learn

169 ls with electromagnetic duality symmetry but broken inversion symmetry.

170 Ergodicity breaking is found to take place due to transient confine

171 An incommensurate phase and symmetry breaking is found within these domains resulting in loca

172 joining (alt-EJ) repair of DNA double-strand breaks is associated with deletions, chromosome transloc

173 either presenting a coherent object but then breaking it into independent parts or presenting an obje

174 ational study, using mechanically controlled break junction measurements and density functional theor

175 junction using the mechanically controllable break junction technique.

176 roscopy, conducting atomic force microscopy, break junction, nanopore, and covalently bridging gaps.

177 ed on >1000 measurements for single molecule break junctions.

178 Here we present Breaks Labeling In Situ and Sequencing (BLISS), featurin

179 f spin-orbit coupling and inversion symmetry breaking, leading to a valley analog of the Zeeman effec

180 C AC genotype with reduced DNA double-strand breaks levels.

181 spatiotemporal modulation of permittivity to break Lorentz reciprocity in a manner compatible with in

182 etChip and the staining of DNA double-strand break marker, gammaH2AX.

183 pecific competitions or alternative symmetry-breaking mechanisms can promote biodiversity to a broade

184 icrobial suspension flows that spontaneously break mirror symmetry.

185 long nights by short pulses of light ("night-break" [NB]) accelerates wheat flowering, suggesting tha

186 The dominant role of symmetry-breaking nO((pi))-sigma*CC interactions between the p-ty

187 balance preserving part and detailed balance breaking non-equilibrium part.

188 ifferent mechanisms depending on whether the breaks occur before or after a learning threshold has be

189 Engineering and enhancing the breaking of inversion symmetry in solids-that is, allowi

190 essive numbers illustrate why the making and breaking of RBCs is at the heart of iron physiology, pro

191 After breaking of spore dormancy, Ctr6 localizes to the vacuol

192 hus a macroscopic witness of the progressive breaking of the tetrahedral hydrogen bond network that m

193 Breaking of Ti-O bonds is found to have little effect on

194 es, the Kelvin and Yanai modes, owing to the breaking of time-reversal symmetry by Earth's rotation.

195 Mathematically they require breaking of time-reversal symmetry, typically achieved u

196 Using the analogy of crystals in space, the breaking of translational symmetry in time and the emerg

197 s, the main transition was identified as the breaking of van der Waals interactions between the acyl

198 The Ru-S bond in Ohki-Tatsumi complexes breaks oligomeric DIBAL-H structures into their more rea

199 ength of the capsid structure and the capsid breaks open.

200 ic reactions occurring with and without bond breaking or bond formation, namely ring-opening reaction

201 not require formation of double-stranded DNA breaks or provision of a donor DNA template.

202 cep-1/p53, endogenous meiotic double strand breaks, or the expression of MIRAGE1 DNA transposons.

203 e scientists hear the word "bioethics," they break out in intellectual hives.

204 The resulting roadmap to symmetry breaking paves the way for deterministic engineering of

205 tity markers are impaired from the "symmetry-breaking" periclinal cell divisions during the transitio

206 f high and low rainfall, known as active and break periods, respectively.

207 of extreme rainfall events, primarily in the break phase of an LF-ISO cycle, reduce the intensity of

208 We identify the parity-time symmetry-breaking phase transition occurring in spin-transfer tor

209 tion in spontaneously time-reversal-symmetry-breaking phases of strongly correlated materials has so

210 see text]-symmetric and [Formula: see text]-broken phases for eigenvalues is theoretically demonstra

211 ons and discoveries of novel Landau-symmetry-broken phases in correlated electron systems, topologica

212 lization of versatile time-reversal symmetry-breaking physics.

213 ivation of MLKL results in the generation of broken, PM "bubbles" with exposed PS that are released f

214 nt environmental source of DNA double-strand breaks, potential drivers of genome structure evolution.

215 lamelets (CF), thin reaction zones (TRZ) and broken reaction zones (BRZ) combustion regimes.

216 nection between cumulene kinking and CC bond-breaking reactions that split off CO.

217 Here we show that it is possible to break reciprocity in static systems, realizing mechanica

218 We anticipate that breaking reciprocity will open avenues for energy absorp

219 ormation of more accessible chromatin in the break regions prior to DNA elimination.

220 ate and its related intra-unit-cell symmetry breaking remain the focus in the research of cuprate sup

221 n DNA base excision repair and single-strand break repair (SSBR) and is important for genetic integri

222 by hiding telomere ends from double-stranded break repair and ATM signaling, whereas POT1 represses A

223 thway plays a critical role in double strand break repair and is uniquely responsible for cellular se

224 est known for its functions in double-strand break repair and resolution of DNA replication stress.

225 However, the interplay between DNA break repair and transcription processivity is unclear.

226 creased RNA polymerase backtracking promotes break repair by instigating RecA loading by RecBCD, with

227 to irradiation and inefficient double-strand break repair correlated with severe late radiation toxic

228 that the transcription factor GreA inhibits break repair in Escherichia coli.

229 A critical step of DNA single-strand break repair is the rapid recruitment of the scaffold pr

230 damage response as well as DNA double-strand break repair through homologous recombination.

231 t role of TCTP in promoting DNA double-stand break repair via facilitating DNA homologous recombinati

232 s, SFPQ and NONO, promotes DNA double-strand break repair via the canonical nonhomologous end joining

233 removal of GreA results in markedly enhanced break repair via the classic RecBCD-RecA pathway.

234 e inactivation, imprinting and double-strand break repair, and mutations in SMCHD1 contribute to a ty

235 4 major subtypes: age related, double-strand break repair, mismatch repair, and 1 with unknown etiolo

236 nuclear genomes through double-stranded DNA break repair.

237 tein complexes involved in DNA single-strand break repair.

238 investigate the quality of the double-strand break repairs in the class-switch recombination process

239 n mobility induced by a single double-strand break requires active microtubule function.

240 ule in the regulation of a key single-strand break resection function of APE2, and also reveal topolo

241 These interactions break reward-seeking habits, a putative factor in multip

242 in breaks, birth-Scan 1) and late pain (skin breaks, Scans 1-2) with thalamic volumes and N-acetylasp

243 mponent configurations wherein symmetric and broken sets are not yet mixed and appear in the neighbou

244 the stability of RAD51 at DNA double-strand break sites and in the overall efficiency of HR.

245 Theoretically, it has been known that breaking spin degeneracy and effectively realizing spinl

246 ons, such as single- and double-stranded DNA breaks (SSBs and DSBs), and single-stranded gaps can blo

247 XRCC1 recruitment at oxidative single-strand breaks (SSBs) as indicated by the requirement for loss o

248 rum of the non-equilibrium (detailed balance broken) statistical system and uncover how switching pol

249 A ground-breaking study by Stephan and co-workers clearly implies

250 Biomolecular machines consume free energy to break symmetry and make directed progress.

251 contractility is sufficiently strong, cells break symmetry and move steadily along either straight o

252 s self-organize and assemble, how the embryo breaks symmetry, and what controls timing and size in de

253 Yet, the electronic properties of these broken symmetry phases are extremely difficult to contro

254 be relevant for the G-protein-based symmetry-breaking systems of higher eukaryotes.

255 s accumulate highly lethal DNA double-strand breaks that are repaired by 2 major mechanisms: BRCA-dep

256 It is suggested that for double-strand DNA breaks that have initially formed a complex with PARP1 a

257 y 2030, national female life expectancy will break the 90 year barrier, a level that was deemed unatt

258 ults encourage an exploration of the ways to break the causal chain between these complex phenotypes,

259 This has led to therapeutic options to break the cycle.

260 eated by an asymmetrical bubble collapse may break the hyaluronan.

261 t any loss of surface soil could potentially break the links between soil biodiversity-fertility and/

262 Their lifestyle, structure, and genomes break the mold of classical viruses.

263 but the steps through which iron species can break the strong (105-111 kcal mol(-1) ) C-H bonds of py

264 h compositional substitution to artificially break the structural inversion symmetry (5-8) .

265 ronment and conformation of Y731, ostensibly breaking the RT pathway in alpha2.

266 In addition, the model fundamentally breaks the defense of modern text-based CAPTCHAs (Comple

267 Toll signaling on the ventral side breaks the Dorsal/Cactus complex, allowing Dorsal to ent

268 d successive substitution of these tyrosines breaks the interaction between ShcD and Grb2, thereby pr

269 Substrate binding breaks the six-fold symmetry of the complex, allowing fi

270 In fish, evasion of a diving bird that breaks the water surface depends on integrating visual a

271 b and Polybrene or DEAE-dextran successfully broke the resistance of HPAF-II cells to VSV by simultan

272 asi-bound state at which the ligand has just broken the most important native contact with the recept

273 g them can be explained by Landau's symmetry breaking theory.

274 Upon GTP hydrolysis, dynamin breaks these necks, a reaction called membrane fission.

275 e can make use of tailored light trapping to break this trade-off.

276 Although photoacoustic tomography breaks this limit by exciting the targets with diffused

277 propose a device concept that fundamentally breaks this paradigm-the sensors remain dormant with nea

278 ZMYM3 is recruited to DNA double-strand breaks through bivalent interactions with both histone a

279 Ratchets operate by breaking time-reversal and spatial symmetries in the dir

280 lve from Dirac semimetals in the presence of broken time-reversal symmetry (TRS) or space-inversion s

281 a much larger coupling of inversion-symmetry breaking to itinerant surface electrons than is typicall

282 iety of systems undergoing the U(1) symmetry-breaking transition.

283 It was due to the lack of broken translational symmetry in two dimensions-doubting

284 mode observed in the time reversal symmetry breaking type II Weyl semimetal YbMnBi2.

285 Model (RBCM), in which discordant links are broken until convergence is reached; and b) the Unbounde

286 cycle of 3 weeks of treatment with a 1-week break, until disease progression, and either oral vandet

287 ions make simplifying assumptions that often break up the dependency between the four processes, or a

288 cts underwent clinical tests (Schirmer I and break-up time), in vivo confocal microscopy (IVCM) and w

289 rthermore, we observe a statistical symmetry breaking upon varying the cavity loss.

290 eposited by e-beam to the eC surface without breaking vacuum protects the surface from the environmen

291 ansitions into spatially ordered states that break various discrete symmetries, verify the high-fidel

292 tivities is its recruitment to double-strand breaks via the interaction of the tandem Tudor domain wi

293 X (gammaH2AX), a marker of DNA double-strand breaks, was increased in vitamin B12 depletion, and this

294 DNA double-strand breaks were determined in peripheral blood mononuclear c

295 DNA double-strand breaks were measured using anti-gamma-H2A.X (phospho S13

296 rl1) is an essential enzyme that repairs RNA breaks with 2',3'-cyclic-PO4 and 5'-OH ends inflicted du

297 x)3 alloys, which we associate with symmetry breaking within the perovskite unit cell.

298 syndrome, are also subject to double-strand breaks within the repetitive tract followed by DNA repai

299 ed phenyl tautomer (2H(+)) prior to C-C bond breaking would produce protonated CO2, an energetically

300 For TRS-breaking WSMs, despite numerous theoretical and experime