ライフサイエンスコーパス: breast cancer gene

1 2, and 3.1% (31 of 1007) in CHEK2 or another breast cancer gene.

2 o 2000 was sequenced for known and candidate breast cancer genes.

3 ined, but <10% were shared with E2-regulated breast cancer genes.

4 identification of additional low-penetrance breast-cancer genes.

5 ely than other women to inherit mutations in breast-cancer genes.

6 Breast cancer gene 1 (BRCA1) deficient cells not only ar

7 Breast cancer gene 1 (BRCA1) mutations predispose women

8 us region of the 1863 residue early onset of breast cancer gene 1 (BRCA1) nuclear protein contains a

9 The carboxyl-terminal domain (BRCT) of the Breast Cancer Gene 1 (BRCA1) protein is an evolutionaril

10 tes binding sites for pairs of BRCT repeats (breast cancer gene 1 [BRCA1] C terminal repeats) in the

11 ing S phase, which recruits Brc1 through its breast cancer gene 1 protein (BRCA1) C-terminal (BRCT) d

12 The Brca1 (breast cancer gene 1) tumor suppressor protein is phosph

13 rotein-protein interaction (PPI) mediated by breast-cancer-gene 1 C-terminal (BRCT) is an attractive

14 4%) carried a pathogenic mutation in another breast cancer gene (29 in CHEK2, and 1 each in BRIP1 and

15 he fact that 5 FA genes are in fact familial breast cancer genes and FA gene mutations are found freq

16 actors; however, the discovery of additional breast cancer genes and genes contributing to racial dis

17 veral panel genes as high- and moderate-risk breast cancer genes and provides estimates of breast can

18 gamma transcription factor regulates luminal breast cancer genes, and loss of TFAP2C induces epitheli

19 pplication in cancer gene diagnostics (BRCA1 breast cancer gene) are investigated.

20 uble-stranded DNA (dsDNA), a sequence of the breast cancer gene BRCA1.

21 gnostic applications in clinical analysis of breast cancer gene BRCA1.

22 e screen for a known polymorphic site in the breast cancer gene BRCA1.

23 ion of adenine and guanine (185delAG) in the breast cancer gene BRCA1.

24 brc-1 and brd-1, the orthologs of the human breast cancer genes BRCA1 and BARD1, respectively.

25 ons have a high penetrance, for example, the breast cancer genes BRCA1 and BRCA2.

26 higher than expected rate of mutation in the breast-cancer gene BRCA1.

27 A second, recently identified familial breast cancer gene, BRCA2, accounts for a proportion of

28 The breast cancer gene, BRCA2, is essential for viability, y

29 The second hereditary breast cancer gene, BRCA2, was recently isolated.

30 ter exclusion of BRCA1, BRCA2, and syndromic breast cancer genes (CDH1, PTEN, and TP53), observed pat

31 The Breast Cancer Gene Database (BCGD) is a compendium of mo

32 investigate long-range interactions at three breast cancer gene deserts mapping to 2q35, 8q24.21, and

33 Breast cancer gene expression analysis correlated estrog

34 We apply BicMix to breast cancer gene expression data and to gene expressio

35 Analysis of breast cancer gene expression data indicates that HOTAIR

36 d utility of this method, we applied it to a breast cancer gene expression dataset and tested its abi

37 ation experiments using multiple independent breast cancer gene expression datasets and PPI networks.

38 rom public data repositories a collection of breast cancer gene expression datasets with over 7000 pa

39 Through integrative analysis of clinical breast cancer gene expression datasets, cell line models

40 essenger RNA (mRNA) profiling of transfected breast cancer gene expression in a living cell is demons

41 ented and performed a large meta-analysis of breast cancer gene expression profiles from 223 datasets

42 rturbations driving most of the variation in breast cancer gene expression.

43 Experiments using three breast cancer gene-expression datasets (i.e., GSE2034, G

44 Furthermore, other breast cancer genes generally are not evaluated.

45 and rearrangements affecting the most common breast cancer genes, including PIK3CA, TP53, PTEN, BRCA2

46 ogenic mutation in BRCA1 or BRCA2 or another breast cancer gene is not known.

47 te that the products of BRCA1, neu, and erbB breast cancer genes participate in a common or shared si

48 We created a breast cancer gene regulatory network comprising transcr

49 nds identified as inversely connected to the breast cancer gene signatures, 14 of them are known anti

50 Identification of high-penetrance breast cancer genes such as Brca1 has been accomplished

51 d expression of a previously uncharacterized breast cancer gene that encodes a secreted protein desig

52 ceptor was expressed in both the ovarian and breast cancers, genes that are coregulated with the estr

53 e that EpCAM is a potential novel target for breast cancer gene therapy and offer insights into the m

54 ess the value of EpCAM as a novel target for breast cancer gene therapy, we performed real-time rever

55 The breast cancer gene trinucleotide-repeat-containing 9 (TN

56 nds was sequenced for 23 known and candidate breast cancer genes using BROCA, a targeted multiplexed