ライフサイエンスコーパス: broad spectrum

1 ty ramp of the target, leading to an overall broad spectrum.

2 ith resistance that is effective, stable and broad-spectrum.

3 ith narrow-spectrum antibiotics, rather than broad-spectrum.

4 Under the tested conditions, a broad-spectrum 2-oxoglutarate dioxygenase inhibitor is a

5 of antimicrobial drugs that have remarkable broad spectrum activity against parasites, mycobacteria,

6 Many of these molecules exhibited broad-spectrum activity against all tested fungal strain

7 proaches or targets for antiviral drugs with broad-spectrum activity.

8 ic prescription; most prescriptions were for broad-spectrum agents (69.9% [95% CI, 69.6% to 70.2%]).

9 minimizing the use of clinically unwarranted broad-spectrum agents.

10 has attracted considerable attention for its broad spectrum and durability, the genetic and mechanist

11 than race-specific resistance because of its broad spectrum and durability.

12 onths of multidrug therapy with a mixture of broad spectrum and mycobacterial specific antibiotics, a

13 To compare the effectiveness of broad-spectrum and narrow-spectrum antibiotic treatment

14 We demonstrated that these drugs are broad-spectrum and reduce cellular sensitivity to other

15 However, clinical trials of these new, truly broad-spectrum, and minimally toxic agents have been few

16 chnological potential use of PRRs to improve broad-spectrum, and potentially durable, disease resista

17 or the discovery of a completely new line of broad spectrum anti-IAV agents.

18 us, suggesting that they represent potential broad-spectrum anti-viral targets.The mechanism underlyi

19 Compound 1 also showed broad spectrum antibacterial activity against Escherichi

20 Nisin is a complex lanthipeptide that has broad spectrum antibacterial activity.

21 hodology was applied to the synthesis of the broad spectrum antibacterial natural product (-)-4-(1,5-

22 alogs of helical, cationic AMPs, which offer broad-spectrum antibacterial activity and better therape

23 logical evaluations eventually confirmed the broad-spectrum antibacterial activity of this new family

24 t is considered to be a promising target for broad-spectrum antibacterial drugs.

25 Axinellamines A and B are broad-spectrum antibacterial pyrrole-imidazole alkaloids

26 Fluoroquinolones are broad-spectrum antibacterials that target DNA gyrase by

27 hether the change of gut microbiota with the broad spectrum antibiotic enrofloxacin will modulate con

28 Oral treatment with a broad spectrum antibiotic modifies gut microbiota compos

29 omptly randomized to receive a standard or a broad spectrum antibiotic treatment.

30 patients with sepsis (i.e., blood cultures, broad-spectrum antibiotic agents, and lactate measuremen

31 The first broad-spectrum antibiotic chloramphenicol and one of the

32 rity of antibiotic exposure in children, and broad-spectrum antibiotic prescribing for acute respirat

33 The broad-spectrum antibiotic prescription relative percenta

34 ription rate for ARTI and a dramatic drop in broad-spectrum antibiotic prescriptions, in favor of amo

35 FMT-randomized patients received 5 days of broad-spectrum antibiotic pretreatment, then a single FM

36 ude that microbiome depletion as a result of broad-spectrum antibiotic treatment disrupts basal Stat1

37 erium Phaeobacter inhibens we found that the broad-spectrum antibiotic tropodithietic acid (TDA) caus

38 patient penicillin allergies results in more broad-spectrum antibiotic use, treatment failures, and a

39 Chloramphenicol (Cam) is a broad-spectrum antibiotic used to combat bacterial infec

40 , pretreatment of donors and recipients with broad-spectrum antibiotics (Abx) or use of germ-free (GF

41 Broad-spectrum antibiotics accounted for 26% of use in S

42 his concept, we depleted gut microbiota with broad-spectrum antibiotics and performed renal ischemia-

43 Broad-spectrum antibiotics are frequently prescribed to

44 Prolonged use of broad-spectrum antibiotics disrupts the indigenous gut m

45 Broad-spectrum antibiotics for recurrent multidrug-resis

46 acute sinusitis), 4307 (14%) were prescribed broad-spectrum antibiotics including amoxicillin-clavula

47 The impact of broad-spectrum antibiotics on antimicrobial resistance a

48 Aminoglycosides (AGs) are broad-spectrum antibiotics that are associated with kidn

49 Aminoglycosides are chemically diverse, broad-spectrum antibiotics that target functional center

50 events documented by the clinician (3.7% for broad-spectrum antibiotics vs 2.7% for narrow-spectrum a

51 .8%]) and reported by the patient (35.6% for broad-spectrum antibiotics vs 25.1% for narrow-spectrum

52 a lower rate of treatment failure (3.4% for broad-spectrum antibiotics vs 3.1% for narrow-spectrum a

53 rse child quality of life (score of 90.2 for broad-spectrum antibiotics vs 91.5 for narrow-spectrum a

54 Broad-spectrum antibiotics vs narrow-spectrum antibiotic

55 Broad-spectrum antibiotics were associated with a slight

56 ren with acute respiratory tract infections, broad-spectrum antibiotics were not associated with bett

57 infectious workup including blood cultures, broad-spectrum antibiotics, and mechanical ventilatory s

58 re infected with VPI 10463 after exposure to broad-spectrum antibiotics.

59 acute sinusitis), 868 (35%) were prescribed broad-spectrum antibiotics.

60 ted with GVHD development and treatment with broad-spectrum antibiotics.

61 sociated gene-7/IL-24 (mda-7/IL-24) displays broad-spectrum anticancer activity in vitro, in vivo in

62 It exhibits broad-spectrum antifungal activity against filamentous f

63 i-domain plant defensin that exhibits potent broad-spectrum antifungal activity, recruits multiple me

64 w the challenges associated with identifying broad-spectrum antifungal drugs and highlight novel targ

65 uture rational development of more efficient broad-spectrum antifungals.

66 mortality rates and length of stay, time to broad-spectrum antiinfective therapy, and compliance wit

67 continuation of our previous reports on the broad-spectrum antimicrobial activity of atmospheric non

68 All of these peptides displayed broad-spectrum antimicrobial activity, validating our LS

69 is study emphasizes the importance of early, broad-spectrum antimicrobial administration in severe se

70 epsilon-Polylysine (epsilon-PL) is a broad-spectrum antimicrobial biopolymer, suitable for us

71 L. reuteri bacteria convert glycerol to the broad-spectrum antimicrobial compound reuterin.

72 Parabens are broad-spectrum antimicrobial preservatives and fragrance

73 Additionally, time to broad-spectrum antimicrobial was associated with progres

74 Triclosan (TCS), a broad-spectrum antimicrobial, is used in commercial toot

75 osterically regulated by ivermectin (IVM), a broad-spectrum antiparasitic agent.

76 ein families is a necessary step in creating broad-spectrum antivenom.

77 We exploit the uniquely broad spectrum antiviral activity of a parainfluenza F-d

78 ttenuated viral RNA production and displayed broad-spectrum antiviral activity against other alphavir

79 LJ001 is a broad-spectrum antiviral compound that inhibits envelope

80 In our studies, we used LJ001, a broad-spectrum antiviral compound that specifically inhi

81 n hamsters can be effectively treated with a broad-spectrum antiviral drug approved for use in Japan.

82 The broad-spectrum antiviral drug Arbidol shows efficacy aga

83 feasibility of developing LIMK inhibitors as broad-spectrum antiviral drugs.

84 ibitors could be developed as a new class of broad-spectrum antiviral drugs.IMPORTANCE The actin cyto

85 transfusion from an Ebola survivor, and the broad-spectrum antiviral GS-5734.

86 e findings identify ZMPSTE24 as an intrinsic broad-spectrum antiviral protein and provide insights in

87 e of innate effector cells in establishing a broad-spectrum antiviral state, as well as providing a b

88 a set of criteria to be used for engineering broad spectrum antivirals for emerging paramyxoviruses.

89 rs of the F508del-CFTR folding defect and as broad-spectrum antivirals against a panel of EVs represe

90 w class of multitarget agents active both as broad-spectrum antivirals and as correctors of the F508d

91 Broad-spectrum antivirals are highly sought after and st

92 ediated inhibition, the potential utility of broad-spectrum aptamers to overcome resistance, and mole

93 s are characterized by high-energies (with a broad spectrum), are emitted in a very directional manne

94 ves the way for the development of selective broad-spectrum bacterial collagenase inhibitors with pot

95 and H2 persisted following administration of broad spectrum bactericidal antibiotics, but ceased foll

96 ental Station in Denmark, we quantified four broad-spectrum beta-lactam AR genes (ARG; bla(TEM), bla(

97 Mycobacterium tuberculosis (Mtb) expresses a broad-spectrum beta-lactamase (BlaC) that mediates resis

98 uberculosis or for escaping to hydrolysis by broad-spectrum beta-lactamase BlaC.

99 trum beta-lactamases (ESBLs), AmpCs, K1, and broad-spectrum beta-lactamases.

100 ature of mite allergens, we have developed a broad-spectrum biochemical method for the standardizatio

101 AcrIIC1 is a broad-spectrum Cas9 inhibitor that prevents DNA cutting

102 e fused Bti's Cyt1Aa to Ls's BinA yielding a broad-spectrum chimeric protein highly mosquitocidal to

103 mposition and diversity induced by long-term broad-spectrum combinatorial antibiotic treatment regime

104 joene could be a lead structure in search of broad-spectrum compounds transcending the Gram negative-

105 ABMA may represent a novel class of broad-spectrum compounds with therapeutic potential agai

106 or the administration of imipenem, which has broad-spectrum coverage of enteric bacteria.

107 We used two broad-spectrum detection strategies to identify pathogen

108 na and AtNPR1 in rice enables us to engineer broad-spectrum disease resistance without compromising p

109 and has been anecdotally linked to enhanced broad-spectrum disease resistance.

110 However, no such molecular targets or broad spectrum drugs have been identified to date.

111 se networks represent attractive targets for broad-spectrum drugs.

112 potential to enable early de-escalation from broad-spectrum empirical antimicrobials to pathogen-dire

113 for pediatric ALL and the first to include a broad-spectrum fluoroquinolone.

114 A new methodology is developed for broad-spectrum GC-MS metabolomics in fruits using a new

115 ns was 40% in the standard versus 46% in the broad spectrum group.

116 caused the same phenotypic changes seen with broad spectrum HDAC inhibitors, most notably a block in

117 The broad-spectrum HDAC inhibitor suberoylanilide hydroxamic

118 (PAT) genes, which convey resistance to the broad-spectrum herbicide phosphinothricin (also known as

119 the isolation, evolution, and structure of a broad-spectrum human monoclonal antibody (mAb), MEDI8852

120 t of new pyrrolidine-2,5-diones as potential broad-spectrum hybrid anticonvulsants was described.

121 nce (SAR), a salicylic acid (SA)-associated, broad-spectrum immune response in systemic, healthy tiss

122 traditional vaccines do not typically induce broad-spectrum immunity.

123 accine efficacy typically focus on providing broad-spectrum immunity; although B and T cells can medi

124 insight into the mechanism of conversion of broad-spectrum immunoglobulin-binding proteins, such as

125 mphocytes-are currently treated using mainly broad-spectrum immunosuppressants that can lead to adver

126 t observed in larger studies, validating its broad-spectrum in vitro activity and suggesting it may b

127 Non-pseudoknot RNA aptamers exhibited broad-spectrum inhibition.

128 In the second case, the affinities of a broad-spectrum inhibitor for 22 bromodomains were calcul

129 Broad-spectrum inhibitors of ABC transport proteins can

130 i, Syn-TEFs convert constituent modules from broad-spectrum inhibitors of transcription into gene-spe

131 modified the initial inhibitors to generate broad-spectrum inhibitors that targeted many SCF ligases

132 of IAV-specific, paramyxovirus-specific, and broad-spectrum inhibitors.

133 2 bound to BI-D1870 and of VRK1 bound to two broad-spectrum inhibitors.

134 thogenic fungus, Metarhizium anisopliae, has broad-spectrum insecticidal effects.

135 Here, we used fipronil, a broad-spectrum insecticide, as a model chemical to probe

136 rosinase PENETRATION2 (PEN2) is required for broad-spectrum invasion resistance to filamentous plant

137 (DARA), a therapeutic human CD38 mAb with a broad-spectrum killing activity, is able to induce progr

138 Therefore, the risks and benefits of using broad-spectrum LRAs need to be carefully evaluated, part

139 In contrast, use of a broad-spectrum matrix metalloproteinase (MMP) inhibitor

140 failed clinical trials has demonstrated that broad-spectrum MMP inhibitors have limited clinical util

141 r of 2-aminoethoxydiphenyl borate (2-APB), a broad-spectrum modulator for a number of membrane protei

142 here is still an ongoing demand for a simple broad-spectrum molecular diagnostic assay for pathogenic

143 Sorafenib (Nexavar) is a broad-spectrum multikinase inhibitor that proves effecti

144 normal mtDNA sequences, methods that detect broad-spectrum mutations with enhanced sensitivity and l

145 th VEGF and Akt signaling, miR-184 acts as a broad-spectrum negative regulator of corneal angiogenesi

146 Developing a sequestrant capable of broad-spectrum neutralization across various protein iso

147 , PA50, a humanized mAb with both potent and broad-spectrum neutralizing activity, in complex with Tc

148 cine target able to induce highly potent and broad-spectrum neutralizing antibodies against infection

149 A broad-spectrum noncompetitive immunoassay allowing sensi

150 Neither broad-spectrum nor narrow-spectrum antibiotics were asso

151 or pretreatment of the olfactory bulb with a broad-spectrum noradrenergic receptor antagonist.

152 extracts, suggesting that Fh15 could have a broad spectrum of action.

153 of novel anti-influenza therapeutics with a broad spectrum of activity against various subtypes is n

154 alyst system for the rapid construction of a broad spectrum of alkylated scaffolds from alkyl zinc re

155 d to produce BrC in aqueous reactions with a broad spectrum of amino acids and amines.

156 ithin a conformational ensemble occur over a broad spectrum of amplitude and time scales, and are oft

157 to show that this mechanism is relevant to a broad spectrum of Antarctic ice shelves.

158 gative pathogens, by efficiently expelling a broad spectrum of antibiotics from the organism.

159 e design of MFCs that enable their use for a broad spectrum of applications ranging from scaled-up po

160 wards the advancement of nano-barcodes for a broad spectrum of applications.

161 urther device performance optimization for a broad spectrum of applications.

162 dioxane over a wide concentration range in a broad spectrum of aqueous matrices was developed.

163 of drugs, potentially useful for treating a broad spectrum of autoimmune conditions in a disease-spe

164 class of cationic lipids characterized by a broad spectrum of bactericidal activity resulting from a

165 of a mutational signature characterized by a broad spectrum of base changes.

166 Plants respond to stresses by producing a broad spectrum of bioactive specialized metabolites.

167 hough Michael acceptors display a potent and broad spectrum of bioactivity, they have largely been ig

168 odiscs provide a new and powerful tool for a broad spectrum of biochemical and biophysical studies of

169 This versatile cell type orchestrates a broad spectrum of biological functions and exerts very c

170 scopy to examine the hydrodynamic radii of a broad spectrum of biologically important RNAs, ranging f

171 th antimalarial drugs for the treatment of a broad spectrum of cancers, many of which will likely ben

172 tems are needed for directing treatment in a broad spectrum of cardiovascular diseases and coagulopat

173 gression of heart failure in patients with a broad spectrum of cardiovascular diseases.

174 Radiology's engagement across a broad spectrum of care provides an excellent opportunity

175 s to VPA in budding yeast, and highlight the broad spectrum of cellular pathways influenced by this c

176 number of these loci, we demonstrate that a broad spectrum of cellular processes contribute to hydro

177 uroinflammation and can induce or modulate a broad spectrum of cellular responses.

178 effects of alertness were uniform across the broad spectrum of CG axonal conduction times.SIGNIFICANC

179 is an inflammatory myeloid neoplasia with a broad spectrum of clinical manifestations and outcomes i

180 vascular disease, and cognitive disorders, a broad spectrum of collateral oral disease may be encount

181 , the increasing resistance of bacteria to a broad spectrum of commonly used antibiotics has become a

182 water, they catalyze peroxide oxidation of a broad spectrum of compounds, many of which are micropoll

183 relaxation of myometrium precontracted by a broad spectrum of contractile agonists, and that targeti

184 Tmem107(-/-) mice were affected by a broad spectrum of craniofacial defects, including shorte

185 onizing STAT3 could lead to suppression of a broad spectrum of cytokines and growth factors to allow

186 When activated, PLCPs induce a broad spectrum of defense responses including plant cell

187 ponse (DDR) is essential for prevention of a broad spectrum of different human neurologic diseases.

188 frared spectrometer with a photorheometer, a broad spectrum of different photopolymerizable formulati

189 n of disaster research stakeholders across a broad spectrum of disciplines.

190 ype of DKD will require a large study with a broad spectrum of disease severity.

191 We studied 20 genotyped ARVC patients with a broad spectrum of disease using electrocardiographic ima

192 (HIV)-associated heart disease encompasses a broad spectrum of diseases.

193 hput platform for nontargeted screening of a broad spectrum of DoA and their metabolites based on mul

194 of insulin and GLP-1 analogs highlights the broad spectrum of drug delivery strategies that have bee

195 The broad spectrum of eIF4F-resistant translatomes is incomp

196 approach to efficient cell replacement for a broad spectrum of endocrine disorders and other organ dy

197 is an attractive antiviral host target for a broad spectrum of established and emerging viral infecti

198 Pf-5 also produces a broad spectrum of exoenzymes and natural products with a

199 While those previous models included a broad spectrum of experimental conditions and dealt only

200 Mitochondrial function refers to a broad spectrum of features such as resting mitochondrial

201 mor and germline WES revealed mutations in a broad spectrum of genes previously implicated in both ad

202 ncer (CRC) is a heterogeneous disease with a broad spectrum of genetic and epigenetic changes.

203 njoys robust prediction performance across a broad spectrum of genetic architectures.

204 Mutations in MED12 are linked with a broad spectrum of genetic disorders with X-linked intell

205 or binding has changed from recognition of a broad spectrum of glycan receptors to a narrower spectru

206 preferentially, the HA190 mutant bound to a broad spectrum of glycans with alpha2,6/8/9-linked siali

207 for the detection and characterization of a broad spectrum of GMOs in routine analysis of food/feed

208 Participants reported a broad spectrum of harms affecting organ recipients, dono

209 ectives on pulmonary hypertension across the broad spectrum of heart failure stages.

210 n combination providing protection against a broad spectrum of herbivores.

211 a devastating agricultural insect pest with broad spectrum of host range, causing million dollars cr

212 A broad spectrum of human diseases called ciliopathies is

213 coding ARS enzymes have been implicated in a broad spectrum of human inherited diseases.

214 asive window for diagnosing and monitoring a broad spectrum of human pathologies as well as providing

215 ed the diagnostic value of IQ-CSF across the broad spectrum of human prions.

216 rial genetics explains how Shigella evades a broad spectrum of immune surveillance systems by coopera

217 rate new technologies for the diagnosis of a broad spectrum of infectious diseases.

218 d coordinate complementary activities from a broad spectrum of innovative researchers clearly benefit

219 come IFN responsive, allowing induction of a broad spectrum of ISGs by IFN signaling.

220 how that the SCOE can be utilized to study a broad spectrum of issues involving the function of skin

221 ials, its geochemistry and geophysics, and a broad spectrum of its industrial chemistry.

222 opt the design to diverse GPCRs that sense a broad spectrum of ligands, including synthetic compounds

223 ategy may open a very promising avenue for a broad spectrum of light-energy-conversion technologies.

224 NIR-II fluorophores draw from a broad spectrum of materials spanning semiconducting nano

225 Among a broad spectrum of medical treatments, protein therapeuti

226 The ability to synthesize a broad spectrum of metal clusters (MCs) with their size c

227 e considered to enhance the elimination of a broad spectrum of micropollutants.

228 hotspots were novel and appeared to affect a broad spectrum of molecular function, including hotspots

229 Our study characterized for the first time a broad spectrum of molecular signatures in AIM and CAEBV.

230 ng of cancer genetic variants, including the broad spectrum of mutation classes and the wide range of

231 active synthetic approach grants access to a broad spectrum of N-benzoylguanidines under mild conditi

232 -34a, a pathogenic microRNA upregulated in a broad spectrum of NAFLD.

233 Preterm infants are at risk for a broad spectrum of neurobehavioral disabilities associate

234 Our patient cohort exhibited a broad spectrum of neurodevelopmental phenotypes, compris

235 n human keratinocytes that are involved in a broad spectrum of nonoverlapping functions.

236 restore exon 7 inclusion in SMN1 carrying a broad spectrum of pathogenic mutations at both the 3'ss

237 ety of dietary products that it absorbs, the broad spectrum of pathogens that it encounters, and the

238 ophy; the encoded proteins are involved in a broad spectrum of pathways.

239 ir and sofosbuvir are highly effective for a broad spectrum of patients with HCV genotype 1 infection

240 tion protocol is safe and effective across a broad spectrum of patients, irrespective of the type of

241 These observations are consistent across a broad spectrum of patients, risk factors, and concomitan

242 games and musical instruments, can impart a broad spectrum of perceptual benefits.

243 elusive, yet is critical to understanding a broad spectrum of phenomena.

244 hertz: ones that prefer to emit a relatively broad spectrum of photon pairs, potentially allowing for

245 hat affects various cellular events during a broad spectrum of physiological and pathological conditi

246 active components, especially because of the broad spectrum of phytochemicals with potential health b

247 Given a broad spectrum of pleiotropic effects of coxibs, our int

248 unctionalization of the BASHY platform for a broad spectrum of potential applications, ranging from b

249 monstrate that cobalamin riboswitches have a broad spectrum of preference for the two biological form

250 prevention of the sepsis-induced surge of a broad spectrum of pro-inflammatory cytokines, including

251 nockdown resulted in impaired induction of a broad spectrum of proinflammatory cytokines, including I

252 Hsp70 participates in a broad spectrum of protein folding processes extending fr

253 to stressors can precipitate the onset of a broad spectrum of psychiatric disorders and addiction in

254 y offer an alternative and is relevant for a broad spectrum of readers because of its clear translati

255 able to achieve human-level performance on a broad spectrum of recognition tasks.

256 Because a broad spectrum of resource use allows species to persist

257 expression levels of Wip1 and PTEN exhibit a broad spectrum of responses to DNA damage: from a fast t

258 re we conduct an extensive study analysing a broad spectrum of RNA-seq workflows.

259 Synaptic excitation mediates a broad spectrum of structural changes in neural circuits

260 art of population genetic studies covering a broad spectrum of taxa including humans.

261 , but also provides a general approach for a broad spectrum of therapeutic proteins for in vivo appli

262 rt and robust and offers rapid delivery of a broad spectrum of tricyclic spiranoid ethers.

263 We elucidated a broad spectrum of tumor suppressor genes (TSGs) and onco

264 gulation of Id proteins is associated with a broad spectrum of tumors, recent studies have identified

265 -scale features with special shapes impart a broad spectrum of unique properties to the surface of in

266 hereby allowing routine quantification for a broad spectrum of usage.

267 le transmembrane proteins (IFITMs) inhibit a broad spectrum of viruses, including HIV-1.

268 a novel class of highly efficient, safe, and broad-spectrum off-the-shelf cancer immunotherapeutics w

269 ng peptide ((10)panx) or the clinically used broad-spectrum Panx1 blockers, mefloquine or probenecid,

270 On the basis of our previous work using a broad-spectrum peptide antagonist imaging 8 chemokine re

271 Additional measures, including extended broad-spectrum perioperative antibiotic treatment, shoul

272 400 IU of vitamin D3 resulted in an enhanced broad-spectrum proinflammatory cytokine response of cord

273 hat the transcription cofactor CRTC1 confers broad spectrum protection against hepatic steatosis deve

274 ify a single siRNA therapeutic that provides broad-spectrum protection against both MARV and RAVV.

275 Potent, broad-spectrum protection by nmAbs holds promise.

276 aptive, flexible cognition are vulnerable to broad-spectrum psychopathology.

277 development of a safe, highly effective, and broad-spectrum RBD-based subunit vaccine to prevent MERS

278 tial need to rethink how the field considers broad-spectrum resistance and how it is affected by gene

279 ce genotypes with either ecotype-specific or broad-spectrum resistance were identified.

280 The broad spectrum showed a lower rate of treatment failure

281 re exploited by multiple viruses could offer broad-spectrum solutions.

282 There are broad-spectrum substances that prevent the first step of

283 oreover, multi-epitope vaccination generated broad-spectrum T-cell responses that potently inhibited

284 have validated its inhibition as a potential broad-spectrum target in oncology and have described sma

285 family Coronaviridae, presenting a possible broad-spectrum therapeutic target.

286 Despite the broad-spectrum therapeutic use of GC, the biochemical ra

287 ion inhibitors and guides the development of broad-spectrum therapeutics against influenza virus.

288 The development of broad-spectrum therapies against members of the Marburgv

289 Use of broad-spectrum therapy and costs have increased.

290 It is not clear whether broad-spectrum treatment is associated with improved out

291 Broad-spectrum treatment was associated with a higher ri

292 Broad-spectrum treatment was not associated with a lower

293 Isavuconazole (ISAV) is a novel, broad-spectrum, triazole antifungal agent (IV and by mou

294 Proteomic analysis suggested that UBE2O is a broad-spectrum ubiquitinating enzyme that remodels the e

295 wisted-nematic orientation, irradiation with broad spectrum ultraviolet-visible light (320-500 nm) tr

296 a significant advance capable of uncovering broad-spectrum utility across many cancer types.

297 the other hand furnish peptides that exhibit broad-spectrum virocidal activity.

298 tors of PI4KB are considered to be potential broad-spectrum virostatics, and it is therefore critical

299 zation with a similar prevalence of MDR (50% broad spectrum vs. 60% standard).

300 d by parametric down-conversion and report a broad spectrum with the angular Schmidt number 82.1.