ライフサイエンスコーパス: bubonic plague

1 nduce the invasive infection associated with bubonic plague.

2 increased virulence and the emergence of the bubonic plague.

3 contributes to disease in the mouse model of bubonic plague.

4 hese MPs significantly increased survival of bubonic plague.

5 play an important role in the progression of bubonic plague.

6 el; however, it was attenuated in developing bubonic plague.

7 med to be important for the establishment of bubonic plague.

8 with antibody therapy in the mouse model of bubonic plague.

9 mination during pneumonic plague than during bubonic plague.

10 imic transmission by fleabite, leads only to bubonic plague.

11 rat closely resembled descriptions of human bubonic plague.

12 es, ranging from food-borne illnesses to the bubonic plague.

13 been proposed to provide protection against bubonic plague.

14 se that is an essential virulence factor for bubonic plague.

15 s ranging from gastrointestinal syndromes to Bubonic Plague.

16 o its current frequency can be attributed to bubonic plague.

17 s ranging from gastrointestinal syndromes to bubonic plague.

18 significantly attenuated in a mouse model of bubonic plague.

19 ifferent stages of the infectious process of bubonic plague.

20 f infection that mimics flea transmission of bubonic plague.

21 r of Yersinia pestis, the causative agent of bubonic plague.

22 Yersinia pestis causes bubonic plague, a fulminant disease where host immune re

23 ions to study bacterial dissemination during bubonic plague and compare this model with an s.c. inocu

24 antibody responses that protect mice against bubonic plague and pneumonic plague, suggesting that rV1

25 Yersinia pestis is the causative agent of bubonic plague and possesses a set of plasmid-encoded, s

26 tigations into the molecular pathogenesis of bubonic plague and the immune response to Y. pestis at d

27 f new vaccines to prevent naturally acquired bubonic plague and to study events at the vector-host in

28 exhibited an exceptional capacity to resist bubonic plague and used it to identify immune mechanisms

29 nt resulted in an atypical, subacute form of bubonic plague associated with extensive recruitment of

30 e clusters are present in the genomes of the bubonic plague bacillus Yersinia pestis and the human an

31 Yersina pestis, the bubonic plague bacterium, is coated with a polymeric pro

32 superfamily, is an effector produced by the bubonic plague bacterium, Yersinia pestis, that is essen

33 Yersinia pestis, the cause of bubonic plague, blocks feeding by its vector, the flea.

34 cells and a large decrease in virulence for bubonic plague but not for pneumonic plague in mice.

35 , spatial metapopulation model, we show that bubonic plague can persist in relatively small rodent po

36 use provides significant protection against bubonic plague caused by an F1- strain (C12) or against

37 In a mouse model of bubonic plague, CCR2 also was shown to be required for D

38 in combination, conferred protection against bubonic plague challenge in mice.

39 Yersinia pestis causes bubonic plague, characterized by an enlarged, painful ly

40 ia pestis is transmitted by fleas and causes bubonic plague, characterized by severe local lymphadeni

41 the more biologically relevant i.d. model of bubonic plague differs significantly from the s.c. model

42 gory BSL 3 and 4 pathogens, such as anthrax, bubonic plague, Ebola and Marburg fever.

43 Yersinia pestis, the agent of bubonic plague, evolved from the enteric pathogen Yersin

44 A mouse model of bubonic plague failed to show a significant role for the

45 le of Yersinia pestis YopJ in a rat model of bubonic plague following intradermal infection with a fu

46 uring infection, but the role of YopJ during bubonic plague has not been completely established.

47 ull pathogenic ability in both pneumonic and bubonic plague in C57BL/6J mice.

48 Bubonic plague in humans follows transmission by infecte

49 ntly caught ill-prepared societies off-guard-Bubonic plague in medieval times, AIDS in the 1980s, and

50 ugh flea-borne transmission usually leads to bubonic plague in mice, it can also lead to primary sept

51 adermal model, suggesting a role for YopM in bubonic plague, in which acute inflammation occurs soon

52 in macrophages and for virulence in a murine bubonic plague infection assay.

53 Here, the historical background of bubonic plague is briefly described and recent studies i

54 ional human-disease models, and propose that bubonic plague is driven by the dynamics of the disease

55 The hallmark of bubonic plague is the presence of grotesquely swollen ly

56 Bubonic plague is transmitted by fleas whose feeding is

57 Bubonic plague is transmitted by fleas whose feeding is

58 Bubonic plague is transmitted to mammals, including huma

59 Bubonic plague is widely regarded as a disease of mainly

60 s of Yersinia pestis, the causative agent of bubonic plague, is the yersiniabactin (Ybt) siderophore-

61 lence of Yersinia pestis, causative agent of bubonic plague, is the yersiniabactin (Ybt) siderophore-

62 Yersinia pestis, the cause of bubonic plague, is transmitted by the bites of infected

63 For bubonic plague, mice dosed with Salmonella-(F1+V)Ags and

64 Brown Norway rat was recently described as a bubonic plague model that closely mimics human disease.

65 tially avirulent via subcutaneous injection (bubonic plague model).

66 tive to the Yfe(+) Feo(+) parent strain in a bubonic plague model.

67 Bubonic plague, one of history's deadliest infections, i

68 pestis against complement-mediated lysis, on bubonic plague pathogenesis in mice and rats.

69 ults indicate that YopJ is not essential for bubonic plague pathogenesis, even after peripheral inocu

70 large-scale food-borne illnesses, dysentery, bubonic plague, secondary hospital infections, and sexua

71 Yersinia pestis, the causative agent of bubonic plague, secretes a eukaryotic-like protein tyros

72 ons, we analyze the full ecoepidemiological (bubonic) plague system.

73 indicating a more important role for RovA in bubonic plague than pneumonic plague or systemic infecti

74 past because it provided protection against (bubonic) plague; the mutation, called CCR5Delta32, is ch

75 ases explored include tuberculosis, leprosy, bubonic plague, typhoid, syphilis, endemic and epidemic

76 We developed a model of bubonic plague using the inbred Brown Norway strain of R

77 The Y. pestis Ail protein is an important bubonic plague virulence factor that inhibits the innate

78 Using a rat model of bubonic plague, we examined lymph node histopathology, t

79 septicemic plague at low incidence, but not bubonic plague, when transmitted by fleas.

80 and Yersinia pestis, the causative agent of bubonic plague, which has a flea vector.

81 on at 8 LD50 when tested in a mouse model of bubonic plague, with infection by 10/20 of the aforement

82 LcrV in the passive transfer of immunity to bubonic plague, with multiple neutralizing epitopes in L

83 y to control malaria, typhus, body lice, and bubonic plague worldwide, until countries began restrict

84 a from the catastrophic European Black Death/bubonic plague (Yersinia pestis).

85 The etiologic agent of bubonic plague, Yersinia pestis, senses self-produced, s