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2 Thus, proteasome inhibitors can affect the budding of a virus that assembles within the cytoplasm.
4 it is rendered PTAP or PPPY dependent; (iii) budding of all EIAV clones is blocked by dominant negati
8 ly reducing WAVE1 in N2a cells decreased the budding of APP-containing vesicles and reduced cell-surf
14 t not catalytically inactive, PLD1 increases budding of betaAPP-containing vesicles from the trans-Go
16 -ribosylation factor appears to regulate the budding of both COPI and clathrin-coated transport vesic
17 G101/ESCRT-I activity and thereby rescue the budding of both mutant Gag particles and HIV-1 viruses l
18 inal fragment of TSG101 (TSG-3') blocked the budding of both PTAP-dependent and PPPY-dependent retrov
19 in disrupted 14-3-3 binding and improved the budding of both virus-like particles (VLPs) and recombin
21 ty not only inhibits GTP-induced fission and budding of caveolae but also prevents caveolae-mediated
24 g, regulation of the immune response and the budding of certain enveloped viruses such as human immun
26 reported that annexin VI is required for the budding of clathrin-coated pits from human fibroblast pl
29 ut by the assembly of clathrin coats and the budding of clathrin-coated vesicles from the neuronal pl
30 inhibition of dynamin, a GTPase required for budding of clathrin-coated vesicles from the plasma memb
31 The large GTPase dynamin is required for budding of clathrin-coated vesicles from the plasma memb
36 to the medial cisternae, and do not inhibit budding of COP-coated vesicles, but do accumulate docked
40 ly of new virions is thought to occur by the budding of core viral particles into a late secretory pa
42 ociated with activation of senescence, while budding of daughter cells was associated with senescence
43 the cell cortex; in particular, the bipolar budding of diploid cells depends on persistent landmarks
46 of human and murine tetherin and facilitated budding of Ebola particles, as did the HIV-1 Vpu protein
51 and that expression of human SOCS3 enhances budding of Ebola VLPs and infectious virus via a mechani
52 mother cell wall, a type of ECM, through the budding of ectosomes directly from the membranes of its
54 s4, and proteasome inhibitors to disrupt the budding of EIAV particles bearing each of the three type
55 erminal TSG101 fragment potently impairs the budding of EIAV when it is rendered PTAP or PPPY depende
57 the p38 alpha and p38 beta isoforms suppress budding of embryonic mouse lung explants and isolated en
62 le formation at the multivesicular body, the budding of enveloped RNA viruses such as HIV-1, and the
63 ecessary and sufficient for the assembly and budding of enveloped virus-like particles from the cell.
66 body sorting, abscission during cytokinesis, budding of enveloped viruses, and repair of the plasma m
67 ular processes such as assembly of caveolae, budding of enveloped viruses, and sorting of lipids and
68 of vesicles into the lumen of endosomes, the budding of enveloped viruses, and the separation of cell
70 of the viral matrix protein (VP) 40 to drive budding of filamentous particles that can also incorpora
71 with others have established that efficient budding of filoviruses, arenaviruses, and other viruses
82 sicular bodies in endolysosomal sorting; the budding of HIV-1 and other viruses from the plasma membr
83 for cytokinesis in animal cells, and for the budding of HIV-1 from human macrophages and T lymphocyte
85 ic vesicles, in contrast to the plasmalemmal budding of HIV-1 typically seen with infected T cells.
90 oviral budding from the plasma membrane, and budding of human immunodeficiency virus type 1 (HIV-1) i
92 ) interactions are necessary to initiate the budding of individual membrane vesicles, the dependence
96 ins, it has been proposed that the polarized budding of influenza virions depends on the interaction
97 atrix protein M1 plays a pivotal role in the budding of influenza virus from the plasma membrane (PM)
99 quire expression of the envelope protein for budding of intracellular capsids from the cell, suggesti
101 RT-III executes membrane scission during the budding of intralumenal vesicles (ILVs) at endosomes.
103 describe a prototype therapeutic that blocks budding of JUNV and has the potential to function as a b
111 s, the lymphatic vascular system develops by budding of lymphatic progenitor endothelial cells from e
112 th in endosomal vesicle formation and in the budding of many enveloped RNA viruses, including HIV-1.
118 step in cellular-trafficking pathways is the budding of membranes by protein coats, which recent expe
120 ic cellular mechanism that results in direct budding of microvesicles from the plasma membrane, provi
121 rom a characteristic pattern of branching or budding of modules, which may remain attached or become
123 und that proteasome inhibition decreased the budding of murine leukemia virus (plasma membrane assemb
124 with mVP40-DeltaLPLGIM successfully rescued budding of mVP40-DeltaLPLGIM into VLPs at mVP40-WT level
126 ons demonstrate that pro-SRIF processing and budding of nascent secretory vesicles from the TGN can b
130 at sites of synaptic growth and facilitates budding of new boutons via a cAMP/PKA-dependent pathway.
132 esicle-Associated Membrane Protein-2 and (c) budding of new recycling sites from previously existing
133 ith endosome-like compartments and, finally, budding of new synaptic vesicles from endosomes, althoug
137 irus morphogenesis that involves a transient budding of newly made immature viral particles into the
140 portion of TSG101 (TSG-3') potently inhibits budding of not only HIV-1 but also murine leukemia virus
141 ovide evidence that MSP export occurs by the budding of novel vesicles that have both inner and outer
142 o help modify the nuclear lamina and promote budding of nucleocapsids at the inner nuclear membrane.
143 (BV) into the host cell and (ii) egress and budding of nucleocapsids newly produced from the plasma
144 ena such as perturbation growth, necking and budding of offspring droplets from a bulk body are obser
145 or depletion of cellular TSG101 reduced the budding of only M40-containing VLPs but not that of wt M
147 stigate this effect further, we examined the budding of other retroviruses from proteasome inhibitor-
150 ding the spike (S) glycoprotein, facilitated budding of particles that contained a corona-like halo r
152 s that regulates segregation, packaging, and budding of peroxisomal importomer subcomplexes, thereby
153 an colonies normally develop through asexual budding of polyps that remain interconnected by continuo
154 Ypt1p to mediate intra-Golgi traffic or the budding of post-Golgi vesicles from the trans-Golgi.
155 functions as an Arf4 effector that regulates budding of post-TGN carriers, along with FIP3 and Rab11.
156 f influenza virus proteins necessary for the budding of progeny virions needs to accumulate at budozo
159 he mouse-adaptive changes did not affect the budding of RAVV VP40 in mouse cells, suggesting that thi
161 , our studies establish a role for NC in the budding of retroviruses harboring divergent L domains an
162 y, we examined a possible role for NC in the budding of retroviruses relying on divergent L domains a
165 mportant role in filovirus budding, and that budding of retroviruses, rhabdoviruses, and filoviruses
169 e data localize the sterol-regulated step to budding of SCAP from ER and provide a system for biochem
170 ein kinase D1 (PKD) that specifically blocks budding of secretory vesicles from the TGN and does not
171 rather than DAG is a key step in regulating budding of secretory vesicles from the trans-Golgi netwo
172 uantitative biochemical assay to monitor the budding of Semliki Forest virus (SFV), an enveloped alph
173 ns into multivesicular bodies (MVBs) and the budding of several enveloped viruses, including HIV-1.
174 s for signal transduction and as the site of budding of several enveloped viruses, including influenz
176 of < or =7.0, conditions that inhibited the budding of SFV but not the budding of the rhabdovirus ve
177 at E2 position 209 is required for complete budding of Sindbis virus particles although several diff
178 tinuous with the plasma membrane; incomplete budding of smaller vesicles from 100nm vesicles further
180 dimer-forming leucine zipper domain restores budding of spherical particles morphologically similar t
181 domains that cause membrane deformation and budding of spherical vesicles, as seen by fluorescent an
183 both M and F proteins are able to drive the budding of SV and propose the possible role of actin in
184 roline in the SV5 M protein resulted in poor budding of SV5 VLPs and failure of recombinant SV5 virus
185 te further the requirements for assembly and budding of SV5, we generated two double-mutant recombina
187 Specifically, we observed defects in the budding of synaptic vesicles from the plasma membrane, i
188 e targeted either toward the reformation and budding of synaptic vesicles, toward secretion via exocy
189 oscopy and super-resolution imaging show the budding of syntaphilin cargos, which then share a ride o
194 genitor cells is impaired due to inefficient budding of the cysts and a failure of the cells in the c
195 ates that ILVs form individually from inward budding of the endosomal limiting membrane, plant ILVs f
197 ing of ubiquitinated cargo with intralumenal budding of the endosomal membrane, two essential steps i
203 examined the role of the MVB pathway in the budding of the late-domain-containing rhabdovirus vesicu
205 FGFR1 signaling results in increased lateral budding of the mammary ductal epithelium, and that susta
207 nsitivity to RET signaling, including excess budding of the ND, increased phospho-ERK and increased e
210 (CME) involves nanoscale bending and inward budding of the plasma membrane, by which cells regulate
211 to 600-nm microvesicles derived from direct budding of the plasma membrane, while the second pool is
212 Native cytosol requires ATP to initiate the budding of the pre-chylomicron transport vesicle from in
213 hat inhibited the budding of SFV but not the budding of the rhabdovirus vesicular stomatitis virus.
214 intra-endoplasmic reticulum (ER) sorting and budding of the RING-domain peroxins (Pex2, Pex10, and Pe
216 ules is determined stochastically during the budding of the somatic organelles from the trans-Golgi n
218 vity is required for both maintenance of the budding of the venous endothelial cells and differentiat
219 ruses of several other families, entails the budding of the viral nucleocapsid through the plasma mem
221 ne indentations rich in PI(4,5)P2 and inward budding of these membrane domains into the lumen of GUVs
224 critical role for late domain motifs in the budding of these viruses, including Ebola virus, it rema
230 act with EH domain proteins that function in budding of transport vesicles from the plasma membrane o
231 inker upstream of the zipper domain leads to budding of tubular rather than spherical particles.
232 ng, as the anchors that induced the greatest budding of TyA-GFP are the same as those that mediate re
233 osphate-binding domain induced only a slight budding of TyA-GFP, approximately 2% of control, and no
234 Gag lacks PPxY motifs, we now show that the budding of various HIV-1 L-domain mutants is dramaticall
235 are believed to support the transport and/or budding of vesicles along microtubules, were tested.
237 atidylethanolamine asymmetry and the dynamic budding of vesicles from the plasma membrane, supporting
241 d pits on the plasma membrane and subsequent budding of vesicles is an energetically demanding proces
244 ruses are complex processes that require the budding of viral nucleocapsids into the lumen of cytopla
245 d is characterized by polarized assembly and budding of virions and clustering of cellular organelles
246 lymphocytes resulted in a massive and rapid budding of virions from lymphocytes, followed by their i
249 gent that interferes with cell migration and budding of virus from lipid rafts, blocks transmission o
251 ate phase of infection for a short duration, budding of virus particles, as determined by protein ana
253 Hrs222-777 can recruit Tsg101 and rescue the budding of virus-like Gag particles that are missing nat
254 owed that the M protein alone can induce the budding of virus-like particles (vesicles) from the plas
255 s the JUNV Z-Tsg101 interaction and inhibits budding of virus-like particles (VLPs) driven by ectopic
256 iphoton fluorescence microscopy to visualize budding of virus-like particles (VLPs) of Rous sarcoma v
257 mammalian cells results in the formation and budding of virus-like particles (VLPs) which mimic the b
258 III filaments, we examine HIV-1 Gag-mediated budding of virus-like particles and find that depleting
261 xpression of a single protein, Gag, leads to budding of virus-like particles into the extracellular s
262 The only retrovirus protein required for the budding of virus-like particles is the Gag protein; howe
263 rvation may reflect either rapid Z-dependent budding of virus-like particles upon coassociation or a
267 s show that proteasome inhibitors reduce the budding of viruses that utilize either a PPPY- or PTAP-b
268 ne fission event topologically resembles the budding of viruses, such as HIV-1, from infected cells.
269 sorting (VPS) machinery, is required for the budding of viruses, such as human immunodeficiency virus
270 us sarcoma virus Gag abolishes formation and budding of VLPs at the plasma membranes of baculovirus-i
276 PTAP and PPEY motifs contribute to efficient budding of VP40-containing VLPs; (ii) PTAP and PPEY can
277 rts a strong dominant-negative effect on the budding of wild-type Gag, further supporting the importa
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