ライフサイエンスコーパス: budding yeast

1 CTD for transcription during mitosis in the budding yeast.

2 or of the unfolded protein response (UPR) in budding yeast.

3 ous genes were analyzed on a global scale in budding yeast.

4 shing PS and PE plasma membrane asymmetry in budding yeast.

5 ng and spindle alignment during metaphase in budding yeast.

6 arget for actin cable assembly regulation in budding yeast.

7 es an attractive and complementary system to budding yeast.

8 en attributed to the metalloprotease Wss1 in budding yeast.

9 s have not been implicated in respiration in budding yeast.

10 CDC) and the yeast metabolic cycle (YMC), in budding yeast.

11 ries of mutants that alter or ablate CTTs in budding yeast.

12 ion on single-cell morphological features in budding yeast.

13 regulate promoters with E2F binding sites in budding yeast.

14 defect conferred by DDK-phosphodead Mcm2 in budding yeast.

15 the morphology of the endocytic membrane in budding yeast.

16 es many of these SUMO-dependent processes in budding yeast.

17 mice, zebrafish, fruit flies, nematodes, and budding yeast.

18 at links mitotic entry to membrane growth in budding yeast.

19 scriptome during the replicative lifespan of budding yeast.

20 rs ago by Louise Clarke and John Carbon from budding yeast.

21 ons as the principal mRNP export receptor in budding yeast.

22 causes and consequences of fork rotation in budding yeast.

23 (NAC) functions during retrotransposition in budding yeast.

24 Puf4 in filamentous fungi than with Puf3 in budding yeast.

25 and in enhancing promoter directionality in budding yeast.

26 ture-compensated respiratory oscillations in budding yeast.

27 red for the initiation of DNA replication in budding yeast.

28 x coimmunoprecipitation (co-IP) assays using budding yeast.

29 0 million years, throughout the evolution of budding yeast.

30 cted role promoting metaphase progression in budding yeast.

31 and regulation of iron in growing fermenting budding yeast.

32 hat controls mitotic exit and cytokinesis in budding yeast.

33 teins in vivo during tethering and fusion in budding yeast.

34 sm for the emergence of copper resistance in budding yeast.

35 conformation and 3D nuclear organization in budding yeast.

36 e signal transduction and gene expression in budding yeast.

37 re immediate effect in the early anaphase of budding yeast.

38 at is called B55 in vertebrates and Cdc55 in budding yeast.

39 owth rate via the TORC2 signaling network in budding yeast.

40 larizes dynein-mediated spindle movements in budding yeast.

41 is play a major role in cell size control in budding yeast.

42 tial to fulfil recombinational DNA repair in budding yeast.

43 g numerous pathways that lack equivalents in budding yeast.

44 one of the two major osmosensing pathways in budding yeast.

45 two splicing isoforms of the same protein in budding yeast.

46 lance of defective nuclear pore complexes in budding yeast.

47 location and role in global transcription in budding yeast.

48 determinant of cell size in bacteria and in budding yeast.

49 CAT-tailing in nascent-chain degradation in budding yeast.

50 themes are beginning to emerge, primarily in budding yeast.

51 ons enriched on chromatin bearing a DSB from budding yeast.

52 We investigated this model in budding yeast.

53 gene expression output, we have conducted in budding yeast a large-scale measurement of the activity

54 In budding yeast, a checkpoint exists that does not allow t

55 In budding yeast, alignment of the anaphase spindle along t

56 re locations from high coverage Hi-C data of budding yeast and a human malaria parasite.

57 proteins, compared with approximately 90 in budding yeast and approximately 140 in humans.

58 In this study, we analyze P bodies in budding yeast and find that they have liquid-like proper

59 Using budding yeast and human cell line model systems, we exam

60 In contrast, herein we analyze Hi-C data for budding yeast and identify 200-kb scale TADs, whose boun

61 ily of endocytic adaptors, including Syp1 in budding yeast and its mammalian orthologue, FCHo1.

62 Budding yeast and several other fungi have small centrom

63 in and regulate force, we purified SPBs from budding yeast and used laser trapping to manipulate sing

64 tochondrial complexes predates the origin of budding yeasts and filamentous fungi and was maintained

65 ofore unknown biological responses to VPA in budding yeast, and highlight the broad spectrum of cellu

66 ific network rewiring between fission yeast, budding yeast, and human.

67 ons that are essential for CAF-1 function in budding yeast, and importantly indicate that the Cac1 su

68 Comparing radiation outcome in fission and budding yeast, and studying meiosis with poisoned microt

69 cycle regulation of actin cable assembly in budding yeast, and suggests an underlying mechanism.

70 urveillance pathways were first described in budding yeast, and there are now high-resolution structu

71 (GPCRs) in cancer cells, xenografts of mice, budding yeast, and zebrafish embryos.

72 its inhibitor Sic1 at the G1/S checkpoint in budding yeast, APC:Cdc20 and its inhibitor MCC at the mi

73 We found that the axial element proteins of budding yeast are flexibly anchored to chromatin by the

74 esions, formed at dysfunctional telomeres in budding yeast, are re-synthesized when cells are removed

75 ut several genes, including the GAL locus in budding yeast, are recruited to the nuclear periphery on

76 We purified budding yeast Arp2/3 complex held in or near the short-p

77 e role of mitochondria in this process using budding yeast as a model.

78 The interaction pattern of budding yeast as measured from genome-wide 3C studies ar

79 Using budding yeast as model, we found that machine learning c

80 the oscillations of the anaphase spindle in budding yeast, but in A. gossypii, this system is not re

81 ons were also observed in vegetative diploid budding yeast, but their functional significance is unkn

82 explored the extent of genomic robustness in budding yeast by genome wide dosage suppressor analysis

83 Dynein mediates spindle positioning in budding yeast by pulling on astral microtubules (MTs) fr

84 -as mutant in the presence or absence of the budding yeast Cak1 kinase, in order to uncouple the CTD

85 experiments have revealed that fungi such as budding yeasts can rapidly develop reproductive isolatio

86 Here we describe the crystal structure of budding yeast Cbk1-Mob2, to our knowledge the first of a

87 Budding yeast Cdh1 carries nine Cdk phosphorylation site

88 a cryogenically cooled biological sample--a budding yeast cell (Saccharomyces cerevisiae)--using har

89 s paper we provide a stochastic model of the budding yeast cell cycle that accurately accounts for th

90 Kar9 positions mitotic spindles during budding yeast cell division.

91 In budding yeast, cell cycle progression and ribosome bioge

92 In budding yeast, cell size is thought to be controlled alm

93 In budding yeast, cell size primarily modulates the duratio

94 In fission and budding yeast, cell-cycle progression depends on cell si

95 r to produce rejuvenated daughters, dividing budding yeast cells confine aging factors, including pro

96 Budding yeast cells exist in two mating types, a and alp

97 Budding yeast cells have a finite replicative life span;

98 Mating of budding yeast cells is a model system for studying cell-

99 elicase function of Dna2 in end resection in budding yeast cells lacking exonuclease 1.

100 in have shown that in response to pheromone, budding yeast cells undergo a rise of cytosolic Ca(2+) t

101 xpressed wild-type levels of mcm10-m2,3,4 in budding yeast cells, we observed a severe growth defect

102 severe growth and DNA replication defects in budding yeast cells, with diminished DDK phosphorylation

103 properties of formaldehyde-cross-linking in budding yeast cells.

104 nized by eisosomes in both fission yeast and budding yeast cells.

105 s a DNA replication defect when expressed in budding yeast cells.

106 dicate aggregate activity observed in living budding yeast cells.

107 One such locus is the budding yeast centromere, which is a paradigm for target

108 distribution of cohesin and condensin in the budding yeast centromere.

109 In budding yeast, centromere establishment begins with the

110 scades orchestrating Rps6 phosphorylation in budding yeast, challenges the notion that Rps6 phosphory

111 to argue that the small, highly constrained budding yeast chromosomes could not have these structure

112 We show here that budding yeast CK1delta, Hrr25, is a gamma-tubulin small

113 a two-dimensional agent-based model to study budding yeast colonies with cell-type specific biologica

114 Purification of budding yeast condensin reveals that it occurs not only

115 report the finding of a new function for the budding yeast Cse4/CENP-A histone-fold domain interactin

116 In particular, budding yeast daughter cells are more vulnerable to stre

117 We find that budding yeast Dbf4-Cdc7 phosphorylates Mcm2 in vivo unde

118 In budding yeast, dicentrics generated by telomere fusion b

119 This mutant, when expressed in budding yeast, diminished cell growth and DNA replicatio

120 2017) have reconstituted rapid and regulated budding yeast DNA replication on naked and chromatinized

121 We used natural budding yeast DNA replication origins and synthetic DNA

122 The spindle pole body (SPB) of budding yeast duplicates once per cell cycle.

123 In budding yeast, dynein is offloaded to Num1 receptors fro

124 In budding yeast, dynein moves the mitotic spindle to the p

125 In budding yeast, each chromosome has a point centromere up

126 Like budding yeast, fission yeast is an important and popular

127 c cells because most prior studies have used budding yeast for RLS studies.

128 IN), we performed genome-wide screens in the budding yeast for yeast genes that cause CIN when overex

129 rm to multicellular filaments is crucial for budding yeast foraging and the pathogenesis of many fung

130 ere are two distinct TRAPP complexes, yet in budding yeast, four distinct TRAPP complexes have been r

131 Budding yeast Fun30 and human SMARCAD1 are cell cycle-re

132 To examine whether budding yeast function at this limit of full ribosomal u

133 ient membrane and cell wall synthesis during budding yeast gametogenesis.

134 The budding yeast genome contains regions where meiotic reco

135 model (mC-SAC) to gain understanding of the budding yeast genome organization.

136 rates for UV-induced lesions throughout the budding yeast genome.

137 Previous studies of laboratory strains of budding yeast had shown that when gene copy number is al

138 d two different strategies for size control: budding yeast has been proposed to use an inhibitor-dilu

139 studies of global chromosome architecture in budding yeast have challenged this view.

140 eukaryotes, and molecular genetic studies in budding yeast have provided critical insights into the f

141 Here we show that in budding yeast, Hsf1 basally associates with the chaperon

142 aggregation and subsequent disaggregation in budding yeast, identifying >170 endogenous proteins aggr

143 In budding yeast, if the spindle becomes mispositioned, cel

144 Here we study budding yeast in dynamic environments of hyperosmotic st

145 series of transcriptome sequencing data from budding yeast, in high temporal resolution over ca. 2.5

146 promoter-proximal pausing is not observed in budding yeast, inhibition of Kin28 attenuates elongation

147 mitochondrial carrier family protein Pic2 in budding yeast is a copper importer.

148 lucose-mediated repression of respiration in budding yeast is at least partly due to the low cellular

149 Heterochromatin formation in budding yeast is regulated by the silent information reg

150 ins in which an induced site-specific DSB in budding yeast is repaired by a 2-kb donor sequence inser

151 One step in this assembly in budding yeast is the association of Cdc45 with the Mcm2-

152 In budding yeast, it is required for the dynamicity of spin

153 to other eukaryotes with symmetric division, budding yeast keeps the nascent transcription rates of i

154 Here, we report that the budding yeast kinesin Kip2 is a microtubule polymerase a

155 d here the forces that ensembles of purified budding yeast kinesin-5 Cin8 produce in microtubule glid

156 The budding yeast kinesin-5 Cin8 was shown to switch from fa

157 optical tweezers to track the path of single budding yeast kinesin-8, Kip3, motor proteins.

158 model of microtubule depolymerization by the budding yeast kinesin-8, Kip3.

159 iscussion, we will use the relatively simple budding yeast kinetochore as a model, and extrapolate in

160 he binding of Bub3-Bub1 and Mad1-Mad2 to the budding yeast kinetochore.

161 We discovered that in budding yeast, kinetochore inactivation occurs by reduci

162 anisms of group formation in the unicellular budding yeast Kluyveromyces lactis.

163 is study, we find that Stu1 recruits Stu2 to budding yeast KTs, which promotes MT generation there.

164 ng stimulates ribosomal DNA amplification in budding yeast, linking external nutrient availability to

165 Msp1 is a conserved AAA ATPase in budding yeast localized to mitochondria where it prevent

166 In this manuscript, we identified a budding yeast Mcm10 mutant (Mcm10-m2,3,4) that is defect

167 slocases, including RNA polymerase, can push budding yeast Mcm2-7 double hexamers along DNA.

168 In budding yeast meiosis, homologous chromosomes become lin

169 In budding yeast, meiotic cells lacking PP2A(Cdc55) activit

170 reveal the structure of the human MIS12 and budding yeast MIND kinetochore complexes and the regulat

171 Here we show that the budding yeast mismatch repair related MutLbeta complex,

172 Here, using the budding yeast model, we show that the abundant PP2A(Cdc5

173 is compartmentalized in cells as diverse as budding yeast, mouse neural stem cells, and the early C.

174 Budding yeast Mph1 helicase and its orthologs drive mult

175 In budding yeast, Mps1 phosphorylation of a central non-cat

176 The budding yeast Mre11-Rad50-Xrs2 (MRX) complex and Sae2 fu

177 Here, we study the budding yeast mutant are1Delta are2Delta dga1Delta lro1D

178 e-wide replication dynamics in a hypomorphic budding yeast mutant, smc6-P4 The overall replication dy

179 Here, we show that in budding yeast, mutations in the DEAD-box ATPase Dhh1 tha

180 omere that challenges this view: that of the budding yeast Naumovozyma castellii is the first unconve

181 Fluorescent labeling of budding yeast nucleoli with CDC14-GFP revealed that a sp

182 work defines spatial organization within the budding yeast nucleus, demonstrates the conserved role o

183 In the small ribosomal subunit of budding yeast, on the 18S rRNA, two adjacent adenosines

184 y, downstream of the Mec1 kinase that is the budding yeast orthologue of mammalian ATR.

185 Boi1 and Boi2 (Boi1/2) are budding yeast plasma membrane proteins that function in

186 In budding yeast, polarization is associated with a focus o

187 The budding yeast Polo-like kinase Cdc5 is a key regulator o

188 Microfluidic experiments on budding yeast populations in space-limited environments

189 d affinities for G-actin and poly-L-proline, budding yeast profilin ScPFY fails to complement fission

190 In budding yeast, proper execution of cytokinesis and cell

191 The budding yeast protein Asr1 is the prototypical member of

192 is essential, we previously interrogated the budding yeast proteome to identify candidates that funct

193 ith our in vitro results, our experiments in budding yeast provide evidence that Rad52 inverse strand

194 Although budding yeast Rad51 has been extensively characterized i

195 The conserved budding yeast Rad51 paralogues, including Rad55, Rad57,

196 In budding yeast, Rad53 (mammalian Chk2) phosphorylation pa

197 Budding yeast Rap1 is a specific double-stranded DNA-bin

198 luded for readers with some familiarity with budding yeast research but who may have an interest in d

199 In budding yeast, resection occurs in two steps: initial sh

200 Here we show that Y1F substitution in budding yeast resulted in a strong slow-growth phenotype

201 its most fundamental level, size control in budding yeast results from the differential scaling of C

202 Comparison of our data with that compiled in budding yeast reveals conservation of SUMO target enrich

203 In budding yeast, Rph1 transcriptionally represses many DNA

204 RCT domain protein Brc1, which is related to budding yeast Rtt107 and mammalian PTIP, plays an import

205 Here, we investigate a conserved scaffold in budding yeast, Rtt107, and its three partners: a SUMO E3

206 provide evidence that the GAL lncRNAs in the budding yeast S. cerevisiae promote transcriptional indu

207 ntrast to the increase upon Puf3 deletion in budding yeast (S. cerevisiae) suggests that the output o

208 The budding yeast Saccharomyces cerevisiae has been used in

209 Starvation of diploid cells of the budding yeast Saccharomyces cerevisiae induces them to e

210 The budding yeast Saccharomyces cerevisiae is a long-standin

211 Under aerobic conditions, the budding yeast Saccharomyces cerevisiae metabolizes gluco

212 of synthetic auxin response circuits in the budding yeast Saccharomyces cerevisiae Our analysis reve

213 The budding yeast Saccharomyces cerevisiae stores iron in th

214 zed a set of strong, synthetic promoters for budding yeast Saccharomyces cerevisiae that are inducibl

215 this obstacle, we engineered strains of the budding yeast Saccharomyces cerevisiae that differ only

216 Ras1 is a small GTPase in the budding yeast Saccharomyces cerevisiae that regulates nu

217 rms multiple vital cellular functions in the budding yeast Saccharomyces cerevisiae These include reg

218 of nuclear microtubule (MT) dynamics in the budding yeast Saccharomyces cerevisiae This activity req

219 ed between S. pombe and the highly divergent budding yeast Saccharomyces cerevisiae Thus, transcripti

220 encing), for mapping hybrid-prone regions in budding yeast Saccharomyces cerevisiae Using this method

221 The alpha pheromone from the budding yeast Saccharomyces cerevisiae, a 13-residue pep

222 n Drosophila melanogaster, the cell cycle of budding yeast Saccharomyces cerevisiae, and the floral o

223 In the budding yeast Saccharomyces cerevisiae, Cdh1 associates

224 In the budding yeast Saccharomyces cerevisiae, ECM remodeling r

225 e, we report on experimental results for the budding yeast Saccharomyces cerevisiae, finding, surpris

226 In the budding yeast Saccharomyces cerevisiae, size control occ

227 In budding yeast Saccharomyces cerevisiae, the ten-subunit

228 in solution with purified proteins from the budding yeast Saccharomyces cerevisiae.

229 regulator dynamics during endocytosis in the budding yeast Saccharomyces cerevisiae.

230 etabolism has motivated domestication of the budding yeast Saccharomyces cerevisiae.

231 c DSBs created by the HO endonuclease in the budding yeast Saccharomyces cerevisiae.

232 ys a central role in zinc homeostasis in the budding yeast Saccharomyces cerevisiae.

233 P protein that is homologous to Glo3p of the budding yeast Saccharomyces cerevisiae.

234 rid speciation in natural populations of the budding yeast Saccharomyces paradoxus inhabiting the Nor

235 We used the budding yeasts Saccharomyces cerevisiae and Torulaspora

236 shed, and some unpublished, tetrad data from budding yeast (Saccharomyces cerevisiae) are analyzed fo

237 cleavage mapping, which revealed that 5% of budding yeast (Saccharomyces cerevisiae) nucleosome posi

238 In budding yeast (Saccharomyces cerevisiae) the multilayere

239 ed a plasmid-based NHEJ DNA repair screen in budding yeast (Saccharomyces cerevisiae) using 369 putat

240 control of autophagic proteasome turnover in budding yeast (Saccharomyces cerevisiae).

241 rotein network that regulates fat storage in budding yeast (Saccharomyces cerevisiae).

242 single-probe FISH protocol termed sFISH for budding yeast, Saccharomyces cerevisiae using a single D

243 The budding yeast, Saccharomyces cerevisiae, harbors several

244 By contrast, a clade of budding yeasts (Saccharomycetaceae) has a "point centrom

245 works to inform inference of networks in the budding yeast Schizosaccharomyces pombe predicts a novel

246 In budding yeast, selection of a bud site directs polarity

247 assembly pathway produces the two species of budding yeast septin hetero-octamers: Cdc11/Shs1-Cdc12-C

248 Work with budding yeast showed that the 'alternative clamp loader'

249 Here, we investigate the role of the budding yeast Shu complex in promoting homologous recomb

250 In budding yeast, size is controlled at the G1/S transition

251 This domain also exhibits homology with budding yeast Sld7.

252 e Arabidopsis RNaseIII enzyme resembling the budding yeast small interfering RNA (siRNA)-producing Dc

253 unctional similarities between Ppc89 and the budding yeast SPB scaffold Spc42, distribution of Sad1 t

254 expressed the human RAD52 gene (HsRAD52) in budding yeast strains lacking the endogenous RAD52 gene

255 triction is transmitted from cell to cell in budding yeast, suggesting that glucose restriction may b

256 iptional splicing and splicing efficiency in budding yeast, suggesting that splicing is more efficien

257 we show that, upon DNA break induction, the budding yeast SUMO ligase Siz2 collaborates with the ssD

258 In budding yeast, targeting of active genes to the nuclear

259 maging and deep sequencing, we show that the budding yeast telomerase RNA (TLC1 RNA) is spatially seg

260 characterized in vivo system using data from budding yeast that have been synchronized in the cell cy

261 Here we present data from budding yeast that is incompatible with this Wpl1p-centr

262 1 is a meiosis-specific MAP kinase (MAPK) in budding yeast that is required for spore formation.

263 We show here, using purified proteins from budding yeast, that Dpb11 alone binds to Mcm2-7 and that

264 his manuscript, using purified proteins from budding yeast, that Mcm10 directly interacts with the Mc

265 InSaccharomyces cerevisiae(budding yeast), the molecular form of environmental nitr

266 In budding yeast, the 3' end processing of mRNA and the cou

267 In budding yeast, the APC/C collaborates with two E2s, Ubc4

268 In budding yeast, the F-box protein Dia2 drives ubiquitylat

269 In budding yeast, the heterotetrameric MIND complex (Mtw1,

270 Here, we show that, in contrast to budding yeast, the horsetail movement is largely radiati

271 In budding yeast, the monopolin complex mediates sister kin

272 In budding yeast, the nuclear RNA surveillance system is ac

273 In budding yeast, the protein Gps1 plays a pivotal role in

274 In budding yeast, the scaffold Bem1 contributes to polarity

275 In budding yeast, the transcription factor Hcm1 activates e

276 ng formation are well studied in fission and budding yeast, there is relatively poor understanding of

277 In budding yeast, this complex is composed of two catalytic

278 lation, we carried out ribosome profiling in budding yeast to characterize 57 nonessential genes invo

279 f truncations and artificial dimerization in budding yeast to define the minimal CPC elements essenti

280 Here, we examine budding yeast to show that more than half of all measure

281 dics to investigate the adaptive response of budding yeast to temporally controlled H2O2 stress patte

282 For example, in the case of the budding yeast transcription factor Msn2, different stres

283 d to control the nuclear localization of the budding yeast transcription factor Msn2.

284 ehensive analysis of nucleosome positions as budding yeast transit through an ultradian cycle in whic

285 Budding yeast Tsr1 is a ribosome biogenesis factor with

286 tubules assembled in vitro from mammalian or budding yeast tubulin.

287 Budding yeast undergoes differentiation to filamentous g

288 strate that the intracellular environment of budding yeast undertakes a startling transition upon glu

289 In budding yeast, unlike mammals, kinetochores are largely

290 ns Mad1 and Bub1 to detached kinetochores in budding yeast using real-time live-cell imaging and quan

291 The kinesin-like protein Smy1 of budding yeast was originally identified by the ability o

292 Using budding yeast, we demonstrate that global genotoxic dama

293 , bead-spring representation of chromatin in budding yeast, we find enrichment of protein-mediated, d

294 In budding yeast, we find that the transcription of nearly

295 In budding yeast, we found that expanded CAG repeats are mo

296 Using a quantitative imaging-based screen in budding yeast, we identified 89 mutants displaying defec

297 Here, using budding yeast, we show that these ATPases function furth

298 Here, this question is addressed in budding yeast, where during meiosis Spr3 and Spr28 repla

299 specific context of mating-type switching in budding yeast, which is a model system for homologous re

300 Budding yeast, which undergoes polarized growth during b