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1 xacerbation rate was reduced by 38.5% versus budesonide.
2 (P= .018) with budesonide/formoterol versus budesonide.
3 success with rifaximin, tinidazole, and oral budesonide.
4 sed release of IL-8, even in the presence of budesonide.
5 eceive placebo or the inhaled corticosteroid budesonide.
6 magnitude as that achieved by treatment with budesonide.
7 , similar in magnitude to that obtained with budesonide.
8 t with B[a]P and similar tumors treated with budesonide.
9 hway and MAPK cascade were also regulated by budesonide.
10 antagonize the effects of dexamethasone and budesonide.
11 significant resistance to chemoprevention by budesonide.
12 flammatory activity to the standard steroid, budesonide.
13 itial study was the synthetic glucocorticoid budesonide.
14 a systemic effect) occurred at all doses of budesonide.
15 were enrolled in a 12-week trial of inhaled budesonide.
16 he suppressive effects of the corticosteroid budesonide.
17 d with IL-17A and/or IL-22, with and without budesonide.
18 a underwent an 8-week treatment with inhaled budesonide.
19 Subjects with incident EoE (n = 25) received budesonide 1 mg twice daily, either nebulized and then s
25 lar in all groups (43 [88%] of 49 in the TRF-budesonide 16 mg/day group, 48 [94%] of 51 in the TRF-bu
28 been randomly assigned to receive 400 mug of budesonide, 16 mg of nedocromil, or placebo daily for 4
29 treatment during pregnancy (n = 1231; 79.9% budesonide, 17.6% fluticasone, 5.4% beclomethasone, and
30 gmoidoscopy and histopathology scores in the budesonide 2.0-mg and 8.0-mg dose groups compared with p
31 50) and the cumulative incidence of relapse (budesonide 20.8% vs. placebo 16.3%, p = 0.547) and non-r
32 HD stage >2 with death as a competing event (budesonide 20.8% vs. placebo 32.6%, p = 0.250) and the c
33 ebulized AZD5423 (75 or 300 mug) once daily, budesonide 200 mug twice daily via Turbuhaler, or placeb
34 16.3%, p = 0.547) and non-relapse mortality (budesonide 28% (95% CI 15-41%) vs. placebo 30% (95% CI 1
35 zed double-blind placebo-controlled trial of budesonide (3 mg/day and 9 mg/day) and prednisolone (7.5
37 re randomised to receive once daily, inhaled budesonide 400 mug (those aged <11 years 200 mug) or pla
38 mmunotherapy; group A (85 patients) received budesonide 400 mug twice daily and group B (40 patients)
39 ar lavage (BAL), subjects were randomized to budesonide (400 microgram, twice daily) or placebo treat
41 of three, in a 1:1:1 ratio to 16 mg/day TRF-budesonide, 8 mg/day TRF-budesonide, or placebo, stratif
42 Following treatment, 34% of patients taking budesonide 9 mg and 46% of those taking prednisolone 7.5
49 Hjortswang-Criteria, 80.0% of patients given budesonide achieved clinical remission compared with 37.
50 election was based on previous work in which budesonide added to the diet was found to inhibit pulmon
51 pical budesonide vs 33 of 105 (31.4%) for no budesonide (adjusted odds ratio, 0.93; 95% confidence in
54 as 12.5% (95% CI 3-22%) under treatment with budesonide and 14% (95% CI 4-25%) under placebo (p = 0.8
55 ngs show that children with asthma receiving budesonide and beclometasone dipropionate have decreased
56 o permeability of two VEGF inhibitory drugs, budesonide and celecoxib, which are lipophilic and neutr
57 rategy has titrated combination therapy with budesonide and formoterol for both maintenance and relie
58 intenance and reliever (SMART) regimen (with budesonide and formoterol fumarate), and anti-IgE therap
59 bo-controlled, multicenter study to evaluate budesonide and mesalamine as short-term treatments for c
60 e long been needed, and recently two agents, budesonide and mycophenolate mofeteil, show promise in t
62 including dexamethasone, methylprednisolone, budesonide, and fluticasone, potentiated TGF-beta signal
65 -controlled studies of IL-5 and oral viscous budesonide as well as new large studies examining the sa
66 symptoms were statistically significant with budesonide at 0.25 mg daily (p = 0.040), 0.25 mg twice d
68 thma (aged>/= 70, n=17) who had treated with budesonide (BUD) 400 mug/day plus Tulo 2 mg/day, were ra
69 ribe interactions between the glucocorticoid budesonide (Bud) and the Smo CRDs from both Drosophila a
70 ned to groups given pH-modified release oral budesonide capsules (9 mg budesonide once daily, Budenof
71 aluated the subgroup of nonsmoking subjects, budesonide caused a significant reduction in nasal condi
73 , and 4.02 for mannitol, sodium fluorescein, budesonide, celecoxib, and rhodamine 6G, respectively.
75 om patients with COPD was less responsive to budesonide compared with those from nonsmokers and smoke
76 pression were sensitive to cyclosporin A and budesonide, compounds that inhibit T cell function, sugg
80 ld recent-onset asthma, once daily, low-dose budesonide decreases SARE risk, reduces lung function de
81 ld recent-onset asthma, once daily, low-dose budesonide decreases SARE risk, reduces lung function de
82 rse events were possibly associated with TRF-budesonide-deep vein thrombosis (16 mg/day) and unexplai
83 A549 pulmonary cells, the dexamethasone- and budesonide-dependent repression of interleukin-1beta-ind
84 ne and budesonide, whilst dexamethasone- and budesonide-dependent repression of nuclear factor-kappaB
85 geted-release formulation of budesonide (TRF-budesonide), designed to deliver the drug to the distal
86 f four clinically important corticosteroids (budesonide, dexamethasone, triamcinolone acetonide, and
91 her cytokines and the topical glucocorticoid budesonide differentially regulate RANTES, monocyte chem
94 os (beclomethasone-chlorofluorocarbon [CFC], budesonide dry powder inhaler [DPI], fluticasone DPI, fl
95 tients' ICS treatments to 180 mug or 200 mug budesonide dry powder inhaler twice daily for the entire
96 els, and AHR remained increased with inhaled budesonide during A alternata exposure, but all features
98 domized to receive either a placebo enema or budesonide enema at a dose of 0.5 mg/100 mL, 2.0 mg/100
103 L-1R2, dexamethasone and, in particular, the budesonide epimer R were shown to effectively and rapidl
105 or ulcerative proctosigmoiditis who received budesonide foam 2 mg/25 mL twice daily for 2 weeks, then
106 -controlled trials evaluated the efficacy of budesonide foam for induction of remission in 546 patien
107 tly more frequently among patients receiving budesonide foam than placebo (Study 1: 38.3% vs 25.8%; P
108 tly greater percentage of patients receiving budesonide foam vs placebo achieved rectal bleeding reso
111 A total of 175 of 437 infants assigned to budesonide for whom adequate data were available (40.0%)
112 e SMART group consisted of two actuations of budesonide-formoterol (200 mug and 6 mug, respectively,
113 tandard group consisted of two actuations of budesonide-formoterol (200 mug and 6 mug, respectively,
114 onist (more than eight actuations per day of budesonide-formoterol in addition to the four maintenanc
117 desonide/formoterol 400/12 mug twice daily + budesonide/formoterol 200/6 mug as needed for 12 weeks.
119 g/d for 2 weeks and maintenance therapy with budesonide/formoterol 400/12 mug twice daily + budesonid
121 erbation occurred in 0 and 4 patients in the budesonide/formoterol and budesonide groups, respectivel
122 piratory tract infection (5.8% and 4.4%) for budesonide/formoterol and budesonide, respectively.
123 , the median FEV1 increased by 260 ml in the budesonide/formoterol arm compared with 5 ml in the plac
124 igned either to change control medication to budesonide/formoterol combination (BUD/FM) 320/9 mug/day
127 pared the efficacy and safety of combination budesonide/formoterol inhaler according to a single inha
128 A large data set from 3 studies comparing budesonide/formoterol maintenance and reliever therapy w
131 were randomized 1:1 to 320/9 mug twice-daily budesonide/formoterol pMDI or 320 mug twice-daily budeso
133 t to assess safety and asthma control with a budesonide/formoterol pressurized metered-dose inhaler (
134 (per patient-treatment year) were lower with budesonide/formoterol versus budesonide (incidence, 7.7%
139 established lung adenomas were treated with budesonide, genotype-dependent differential effects of b
140 which the inhibitory effects of aerosolized budesonide, given for 1 min six times a week, were studi
141 </= 0.050) and 27% of patients in the 8.0-mg budesonide group (P </= 0.001) compared with 4% in the p
142 as achieved in 19% of patients in the 2.0-mg budesonide group (P </= 0.050) and 27% of patients in th
143 red in 17% (95% CI 6-28%) of patients in the budesonide group and 19% (CI 7-32%) in the placebo group
145 st 2 years, decreased growth velocity in the budesonide group occurred primarily in prepubertal parti
146 nfidence interval [CI], -1.9 to -0.5) in the budesonide group than in the placebo group (P=0.001) and
147 a patent ductus arteriosus was lower in the budesonide group than in the placebo group (relative ris
148 bronchopulmonary dysplasia was 27.8% in the budesonide group versus 38.0% in the placebo group (rela
149 A greater percentage of patients in the budesonide group were in clinical remission at week 8 th
151 rcine models was 3H-mannitol > fluorescein > budesonide > celecoxib > rhodamine 6G, with HPbetaCD, an
154 inue to demonstrate that steroids, including budesonide, have a greater acute benefit than aminosalic
155 ed the abilities of mesalamine, antibiotics, budesonide, immunomodulators, anti-tumor necrosis factor
159 in 3 times per day for 7 days and 200 mug of budesonide in each nostril once per day for 10 days.
160 ty of three doses of an enema preparation of budesonide in patients with active distal ulcerative col
161 uate the safety and estimate the efficacy of budesonide in patients with PBC, who have shown a subopt
163 Four formulations of albuterol sulfate and budesonide in sieved and milled lactose, respectively, w
164 indicate that the chemopreventive effects of budesonide in the mouse lung tumorigenesis assay involve
165 hase III trial, we evaluated the efficacy of budesonide in the prophylaxis of acute intestinal GvHD a
166 ion, showed much lower systemic effects than budesonide in the thymus involution test, and possessed
167 , genotype-dependent differential effects of budesonide in wild-type and mutant mice were clearly rev
168 were lower with budesonide/formoterol versus budesonide (incidence, 7.7% vs 14.0% [P= .006]; rate rat
170 trospective analysis suggests that nebulized budesonide inhalation suspension can be administered eff
171 Children were randomly assigned to receive a budesonide inhalation suspension for 1 year as either an
172 ates demonstrated the efficacy and safety of budesonide inhalation suspension in doses of 0.25 mg onc
177 At concentrations devoid of cytotoxicity, budesonide inhibited VEGF secretion as well as mRNA expr
178 ective for proinflammatory cytokines because budesonide inhibition of LPS-stimulated IL-10 release wa
179 rpose of this study was to determine whether budesonide inhibits expression of vascular endothelial g
185 alicylates are therapeutic options; however, budesonide is more effective in achieving clinical and h
187 nano- and microparticles produced sustained budesonide levels in the retina and other ocular tissues
191 randomly assigned to groups that were given budesonide MMX (9 mg or 6 mg), mesalamine (2.4 g, as ref
193 controlled trial to evaluate the efficacy of budesonide MMX for induction of remission in 509 patient
194 at week 8 among subjects given 9 mg or 6 mg budesonide MMX or mesalamine were 17.9%, 13.2%, and 12.1
195 at week 8 among subjects given 9 mg or 6 mg budesonide MMX or mesalamine were 28.5%, 28.9%, and 25.0
196 at week 8 among patients given 9 mg or 6 mg budesonide MMX or mesalamine were 33.3%, 30.6%, and 33.9
197 at week 8 among subjects given 9 mg or 6 mg budesonide MMX or mesalamine were 41.5%, 35.5%, and 33.1
199 in autoimmune hepatitis, and, in contrast to budesonide, mycophenolate mofetil has been effective in
200 ce therapy (n = 15); (2) currently receiving budesonide (n = 10); and (3) currently receiving oral pr
201 nal GvHD until day 100 observed in 91 (n =48 budesonide, n =43 placebo) evaluable patients was 12.5%
203 rmine whether subconjunctivally administered budesonide nano- and microparticles sustain retinal drug
204 hort, which was randomly assigned to receive budesonide, nedocromil, or placebo for 4-6 years, we det
208 though the intermittent-treatment group took budesonide, on average, for only 0.5 week of the year.
209 ified release oral budesonide capsules (9 mg budesonide once daily, Budenofalk, n = 30), mesalamine g
210 g analyses with the major subgroup that used budesonide only, association estimates were of similar m
211 Treatment of MSCs with glucocorticoids, budesonide or dexamethasone, enhanced IDO expression fol
212 odium-induced colitis, the platform carrying budesonide or mesalamine becomes more viscoelastic near
213 ition to daily treatment with either inhaled budesonide or oral zafirlukast over a one-year period.
214 early (within 24 hours after birth) inhaled budesonide or placebo until they no longer required oxyg
216 cal corticosteroids, such as fluticasone and budesonide, or dietary strategies, such as amino acid-ba
218 io to 16 mg/day TRF-budesonide, 8 mg/day TRF-budesonide, or placebo, stratified by baseline urine pro
219 olled phase 2 trial to assess the ability of budesonide oral suspension (BOS), a novel muco-adherent
221 essurized metered-dose inhaler (pMDI) versus budesonide over 1 year in African American patients.
222 ter demonstrated a positive response to both budesonide (P = .02) and nedocromil (P = .01) compared w
223 uster demonstrated minimal responses to both budesonide (P = .12) and nedocromil (P = .56) compared w
226 r inhaled corticosteroid exposure (943.5 mug budesonide per day [1502.5] vs 684.3 mug budesonide per
227 mug budesonide per day [1502.5] vs 684.3 mug budesonide per day [390.5], respectively; ratio of means
228 ause of the poor solubility of celecoxib and budesonide, permeability studies were conducted with 5%
230 After subconjunctival administration, both budesonide-PLA nano- and microparticles produced sustain
233 f budesonide plus formoterol with fixed-dose budesonide plus formoterol and fixed-dose fluticasone pl
234 ), 2250 asthmatics were randomly assigned to budesonide plus formoterol maintenance and reliever ther
235 matics and compared an adjustable regimen of budesonide plus formoterol with fixed-dose budesonide pl
236 maintenance and reliever therapy, fixed-dose budesonide plus formoterol, or fixed-dose fluticasone pl
237 After 2 weeks using a 320 mug twice-daily budesonide pMDI, patients were randomized 1:1 to 320/9 m
239 ted 4-fold enhanced IDO activity compared to budesonide preconditioned and naive MSC, resulting in a
244 d, phase 3 trials to evaluate the ability of budesonide rectal foam, formulated to optimize retention
246 uggest that long-term treatment with inhaled budesonide reduces airway cell generation of cytokines,
248 oral formulation of budesonide that extends budesonide release throughout the colon using multi-matr
251 esalamine (RR, 0.67; 95% CrI, 0.39-1.08) nor budesonide (RR, 0.86; 95% CrI, 0.61-1.22), reduced the r
252 rapy (RR, 0.04; 95% CrI, 0.00-0.14), but not budesonide (RR, 0.93; 95% CrI, 0.40-1.84), reduced the r
253 orticoid receptor in the observed effects of budesonide, secretion and mRNA expression studies were a
256 lower among those who received early inhaled budesonide than among those who received placebo, but th
257 e MMX(R) is a once-daily oral formulation of budesonide that extends budesonide release throughout th
258 s successfully treated with prednisolone and budesonide, the model will be helpful to develop and tes
259 hs, with a safety profile similar to that of budesonide; the asthma exacerbation rate was reduced by
260 therapy or daily zafirlukast therapy, daily budesonide therapy produced greater improvements in pre-
264 ze retention and provide uniform delivery of budesonide to the rectum and distal colon, to induce rem
270 ) were modulated back to normal levels after budesonide treatment when compared with the controls gro
271 ms complicated conversion from prednisone to budesonide treatment, and every patient developed at lea
274 y of a novel targeted-release formulation of budesonide (TRF-budesonide), designed to deliver the dru
275 were randomly assigned to 200 mug of inhaled budesonide twice per day (n = 84) or placebo (n = 56) fo
276 whether there was a differential response to budesonide versus placebo for severe asthma exacerbation
279 medication was reduced in patients receiving budesonide via face masks or mouthpieces relative to pla
280 more days were 32 of 102 (31.4%) for topical budesonide vs 33 of 105 (31.4%) for no budesonide (adjus
282 bo-controlled, cross-over study with inhaled budesonide was conducted in 14 subjects with allergic as
283 thy of rigorous study in severe disease, and budesonide was endorsed for study as front-line therapy
289 able when cells were continuously exposed to budesonide, we engineered MSC with budesonide loaded PLG
291 de (PLA) nano- and microparticles containing budesonide were prepared by a solvent evaporation techni
292 ed by RU486 but induced by dexamethasone and budesonide, whilst dexamethasone- and budesonide-depende
293 study (FACET) in which low and high doses of budesonide with and without formoterol were compared in
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