ライフサイエンスコーパス: buffering

1 oked currents with high intracellular Ca(2+) buffering.

2 MODIS images, to demonstrate hydrogeological buffering.

3 uch as Hsp70 and Hsp90 do not correlate with buffering.

4 er WAT compartment, and had improved glucose buffering.

5 d there is limited evidence of translational buffering.

6 ulting from compromised intracellular Ca(2+) buffering.

7 othelin-1 (ET-1) is important for skin Na(+) buffering.

8 (2+)]i transients and prevented by [Ca(2+)]i buffering.

9 antagonist blocked the effects of the social buffering.

10 of mRNA degradation, resulting in mRNA level buffering.

11 evidence of diminished mitochondrial Ca(2+) buffering.

12 nsitive to the amount of cytoplasmic calcium buffering.

13 extracellular Ca(2+) or intracellular Ca(2+) buffering.

14 s on mNCE activity and mitochondrial calcium buffering.

15 ed currents with modest intracellular Ca(2+) buffering.

16 ith temporally precise intracellular calcium buffering.

17 ced an unobserved stressor, providing social buffering.

18 ins most of its refreezing capacity for now, buffering 22% of the increased meltwater production.

19 This modification did not affect the PEI buffering abilities but enhanced its pH-sensitive aggreg

20 CHA and maximizes its thermo- and structure- buffering abilities.

21 a golden standard polymer owing to its high buffering ability for endosomal escape of gene to be exp

22 This novel buffering activity of SLiMs was observed in different ti

23 cg) 1 serves a seminal physiological role in buffering against hypoglycemia, but its poor biophysical

24 nditions within each year-class, and reduced buffering against negative environmental influences.

25 ghlights the neuroprotective role of glial K buffering against seizures and spreading depression, and

26 hortening and thus preventing the clock from buffering against this change in temperature.

27 ting carbon sequestration and storage and by buffering against uncertainty in management, environment

28 ferences in temperature, pH, ionic strength, buffering agent, or other additives can alter chemical e

29 esolution, (ii) the effect of excipients and buffering agents, (iii) the performance of the assay com

30 ptation potential and ecological benefits by buffering alley crops to weather extremes, diversifying

31 Demographic buffering allows populations to persist by compensating

32 because of high energy needs and calcium ion buffering along axons to synapses during neurotransmissi

33 ely, land-use change might overwhelm natural buffering and amplify latent climate signals, rendering

34 , with differential effects on matrix Ca(2+) buffering and DeltaPsim recovery.

35 provide new insights into intracellular zinc buffering and may have broad relevance given the presenc

36 ion is mutualistic or commensal, there is no buffering and only monotonic toxic responses are possibl

37 or carbon storage and sequestration [8], for buffering and regulating local climates [9], and for sup

38 In this model, uncoupling impaired K(+) buffering and temporally preceded apoptotic neuronal dea

39 ns in the kinetics of perisynaptic glutamate buffering and uptake contributing to dysfunction of thal

40 gorithm that includes channel gating, Ca(2+) buffering, and Ca(2+) diffusion.

41 EPSP/AP pairing or high intracellular Ca(2+) buffering, and its sign was inverted by GABA-A receptor

42 y extracellular Ca(2+), intracellular Ca(2+) buffering, and membrane potential, by their common effec

43 s, including neurotransmitter clearance, ion buffering, and metabolite delivery.

44 n of supramolecular ring-chain buffering, pH buffering, and molecular titration is presented.

45 imary forests in their potential for thermal buffering, and subsequent ability to retain temperature-

46 tion pipeline facilitating Ca(2+) diffusion, buffering, and synchronicity.

47 actile muscles as a results of their role as buffering, anti-oxidative, and anti-glycation capacities

48 excess buffer approximation (EBA), the rapid buffering approximation (RBA), and the linear approximat

49 te Ciona intestinalis to show that levels of buffering are maternally inherited.

50 We now show that buffering astrocyte Ca(2+) inhibits neuronally evoked ca

51 It was suppressed by intracellular Ca(2+) buffering at a fixed physiological level, inhibitors of

52 steady-state glutamate uptake and glutamate buffering at the synapse.

53 ands; exposure to 12% CO2 without additional buffering blocked ligand shedding, as well as EGFR and p

54 ults showed a slow pH increase due to strong buffering by Al hydrolysis and precipitation and CO2 upt

55 boratory trials, we demonstrate that thermal buffering by centimetre-thick mussel and seaweed beds el

56 xotomized SNL L5 neurons but enhanced Ca(2+) buffering by neurons in adjacent SNL L4 neurons.

57 the design principles of the supramolecular buffering by ring-chain competition using a combined exp

58 metabolic acid load requiring excretion and buffering by the kidney.

59 This social buffering by the male partner on biobehavioral responses

60 acts locally to control the pH by modulating buffering by the NADPH oxidase NOX2.

61 y active positive feedback in the absence of buffering by the negative feedback.

62 Ns, enhanced mGluR1 function is prevented by buffering [Ca(2+)] at normal resting levels while in wil

63 xons from stress and insults, for example by buffering calcium [8].

64 At both frequencies, buffering calcium prevents LTD induction and LTP results

65 ribe a novel mechanism by which increased Ca buffering can account for changes to systolic Ca(2+) in

66 Furthermore, we predict that supramolecular buffering can be significantly improved using a tetraval

67 ct where even-valent molecules show superior buffering capabilities.

68 at the site, and the depletion of Al mineral buffering capacity after approximately 5 years.

69 The very high buffering capacity allows the Mediterranean Sea waters t

70 ondria exhibit reduced mitochondrial calcium buffering capacity and are highly sensitive to mitochond

71 n significantly reduced saliva flow rate and buffering capacity and increased mucus acidity.

72 ructure with the potential to extend stretch-buffering capacity and support a revised model for the f

73 tablish a close link between nuclear calcium buffering capacity and the transcription of genes that d

74 f RVH rats, and (2) that a blunted ER Ca(2+) buffering capacity contributes to the altered NMDAR-Delt

75 s also indicated that algae have substantial buffering capacity for free heavy metals in their cytoso

76 tween intermittent contractions and inherent buffering capacity had minimal impact on predicted fatig

77 cell patch-clamp dialysis and quantified its buffering capacity in murine hippocampal slices using co

78 m human brain that suggested loss of calcium buffering capacity in neurons correlated with areas of n

79 r has proven challenging because of a signal buffering capacity inherent in the functionally relevant

80 ticular, it suggests that the Class 1 Ca(2+) buffering capacity is auto-regulated by the rate at whic

81 Mitochondria also buffer Ca(2+), and their buffering capacity is dependent on DeltaPsi Here, we cha

82 These findings highlight the buffering capacity of developmental systems, allowing ma

83 ty is important for cell uptake and that the buffering capacity of histidine facilitates endosomal me

84 eir virulence varied depending on the pH and buffering capacity of host tissue.

85 er, in a physiological situation, the Ca(2+)-buffering capacity of mitochondria was found not to be e

86 -producing S. gordonii is dominant while the buffering capacity of saliva is valid ( approximately pH

87 vironment can vary depending on the diet and buffering capacity of saliva, materials testing in const

88 ification in the surface ocean decreases the buffering capacity of seawater for CO2, whilst photosynt

89 f biodiesel wastewater and by increasing the buffering capacity of the anode medium.

90 Here we show that the calcium buffering capacity of the cell nucleus in mouse hippocam

91 obal temperature change based on the thermal buffering capacity of the germination phenotype.

92 antitative imaging experiments show that the buffering capacity of the nerve terminal is markedly low

93 The mechanical stability and buffering capacity of this hydrogel can be adjusted by w

94 n the bacterial cells and facilitated by the buffering capacity of yogurt.

95 ribution of the loss of mitochondrial Ca(2+)-buffering capacity to disease mechanism(s) by eliminatin

96 s of this neurocircuitry maintain sufficient buffering capacity to resist an effect on motivated beha

97 Reducing HSP90's buffering capacity with inhibitors or febrile temperatur

98 t to the lung, nor a change in eosinophil pH-buffering capacity, allergen-challenged chimeric mice th

99 t SOD1-mediated loss of mitochondrial Ca(2+) buffering capacity, altered mitochondrial morphology, mo

100 ter absorption, nutrient inflow, and luminal buffering capacity, and generates testable predictions o

101 activation, loss of glutamate and potassium buffering capacity, loss of astrocyte coupling, and chan

102 Together they lead to a poor acid buffering capacity, severe acidification and increased c

103 n juxtanuclear ones despite their comparable buffering capacity.

104 due to blunted endoplasmic reticulum Ca(2+) buffering capacity.

105 portant for matching local energy and Ca(2+) buffering capacity.

106 ow level of atmospheric CO2 and a high ocean buffering capacity.

107 e, limited hydraulic conductivity, and redox buffering capacity.

108 gentler droplet environment, despite its low buffering capacity.

109 of calcium, increasing the lysosomal Ca(2+) buffering capacity.

110 Thus, we can realize a buffering-capacity independent monitoring of changes in

111 tensively in many species, and a function in buffering carbon availability or in fueling later growth

112 further suggest a novel role for this Obp in buffering changes in the odor environment, perhaps provi

113 ree buffer concentration for a wide range of buffering conditions.

114 roximation (LIN), each valid for appropriate buffering conditions.

115 ease (IICR) and reduced mitochondrial Ca(2+) buffering, consistent with a reduced mitochondrial densi

116 s for non-local resource access and resource buffering, crucial in the human foraging niche, will inc

117 (DeltaPsim), the role of the mitochondria in buffering cytosolic Ca(2+) signals was investigated.

118 Buffering DAMGO-induced changes in [Ca(2+)]i with BAPTA-

119 ight a novel mechanism by which increased Ca buffering decreases systolic Ca(2+) in old atria.

120 However, the exact magnitude of spatial buffering depends upon demographic parameters such as ad

121 nutrient transfer continuum based on soil P buffering, depth to bedrock, and retention within the aq

122 Bicarbonate-derived buffering did not contribute to buffering of acid loads

123 lic acidosis and that compensation with bone buffering does take place.

124 ed that canopies played an important role in buffering dry Ndep also at the low Ndep site.

125 n channels, maximal conductances, and Ca(2+) buffering each have independent temperature sensitivitie

126 re at ground level within a forest, with the buffering effect being stronger below-ground than one me

127 d differentiate new adipocytes, prevents its buffering effect in obesity and is characterized by expa

128 Our results suggest that the buffering effect of a geographically wide distribution o

129 tlantic forests of Brazil, we found that the buffering effect of forests reduced maximum outside temp

130 The buffering effect of hematite was further supported by a

131 esponses in numerous species, but the stress-buffering effect of status may dissipate or even reverse

132 rvations of plague resistance and reveal the buffering effect of such evolution against environmental

133 r data show how chemical stresses can reduce buffering effects in the ubiquitin proteasome system.

134 tance of microbial community composition for buffering effects of global change in drylands worldwide

135 tbred adults, suggesting that the beneficial buffering effects of maternal care can persist long afte

136 Thermal buffering effects of soil can reduce exposure to extreme

137 ricular nucleus oxytocin mediates the social buffering effects on the stress response and thus may be

138 s consistent with a role as flexible rods in buffering elastic power transmission between the domains

139 ults lead to the concept that reduced Ca(2+) buffering enables fast active zone Ca(2+) signaling, sug

140 Furthermore, imaging, simulations, and buffering experiments all support a model whereby fast N

141 An increase in intracellular Ca buffering explains both the decrease in Ca(2+) transient

142 These buffering features also occur in other genes in Drosophi

143 e been used as a dietary supplement and risk-buffering food in ancient Teotihuacan (150 B.C. to A.D.

144 l-level variation; b) provides advantages in buffering food risk, and is positively associated with b

145 maintaining balanced hematopoietic output by buffering FOXO3 expression.

146 he initial assembly of metastable structures buffering free monomers and thereby slows the formation

147 This buffering function is most visible after fasting, when l

148 nduce zinc efflux by interfering with the Zn-buffering function of BSH.

149 In addition to its buffering function, AT is also a target of POPs and may

150 arch and policy interventions geared towards buffering future crop production from climate variabilit

151 astrocyte Ca(2+) and Na(+) signalling, K(+) buffering, gap junction coupling and metabolism.

152 t libraries to identify synthetic lethal and buffering gene pairs across multiple cell types, includi

153 In terms of pH regulation, HCO3 (-) buffering has been shown to be important in both glia an

154 This phenotypic buffering has been theorized to arise from a variety of

155 ss; thus, we focus on the impact that social buffering has on the stress response and the governing e

156 viding evidence that purifying selection and buffering have limited the deleterious impact of regulat

157 Depriving NHEs of intracellular protons by buffering HC cytosol with a pH 9.2 pipette solution elim

158 Oxytocin (OT) is considered to be a stress-buffering hormone, dampening the physiologic effects of

159 ote CO2 removal from the atmosphere, thereby buffering human effects on global radiative forcing.

160 The addition of a Na(+) buffering hydrogel layer between the SiO2 of the SiNW an

161 The social buffering hypothesis conceptualizes one possible mediati

162 r bond broadens the generality of the social buffering hypothesis.

163 , lowers resting [Ca2+]SR and alters SR Ca2+ buffering in a way that copies the functional instabilit

164 out the role and relative importance of zinc buffering in all organisms.

165 , our findings identify failure of potassium buffering in astrocytes as a crucial mechanism in ammoni

166 indings show diminished mitochondrial Ca(2+) buffering in axotomized SNL L5 neurons but enhanced Ca(2

167 ensitive to blockade of mitochondrial Ca(2+) buffering in order to assess mitochondrial contributions

168 n transport on mitochondrial Ca(2+) flux and buffering in Pi-depleted guinea pig cardiac mitochondria

169 esults demonstrate conclusively that calcium buffering in the mitochondrial matrix in live cells occu

170 cid involved in adenosine triphosphate (ATP) buffering, in oligodendrocyte function.

171 g activity had very little effect on thermal buffering, in terms of macroclimate and microclimate tem

172 patic glucose metabolism was not affected by buffering InsP3 in the nucleus.

173 art, enhancing physiological performance and buffering internal organ function while foraging in the

174 Mitochondria play central roles in buffering intracellular Ca(2)(+) transients.

175 when Ca(2+) release sites were uncoupled by buffering intracellular Ca(2+) with EGTA-AM.

176 Buffering intracellular calcium with EGTA-AM or BAPTA-AM

177 rocyte [Ca(2+)]i, [Mg(2+)]i and [H(+)]i, and buffering intracellular pH reduces the [Ca(2+)]i and [Mg

178 gulator of SLC4A4 and CFTR, encoding the key buffering ion transporters, in modulating enamel mineral

179 tion, pointing to a role for this protein in buffering iron availability and facilitating iron-sparin

180 Molecular buffering is achieved as a result of competition in a ri

181 This conditional buffering is confined to the scaffold module, but contro

182 we still do not understand how the level of buffering is controlled in natural populations.

183 nsmission, mitochondrial fusion, and calcium buffering, is complex and was differentially regulated a

184 Zn(2+)-binding mutants by binding Zn(2+) and buffering it to a level such that Zn(2+) can repopulate

185 ntransitivity increased with aridity, partly buffering its negative effects on diversity, but was dec

186 e I(2)PS hollow fiber is found to serve as a buffering layer that mitigates hydraulic compression on

187 teins (HSPs) can be used as a measurement of buffering levels, we propose that ER associated chaperon

188 sting that the strength of endogenous Ca(2+) buffering limits the rate of synchronous synaptic transm

189 stress, social support can serve as a potent buffering mechanism that enhances resilience.

190 urrent connections and functions as a strict buffering mechanism that maintains a roughly constant av

191 n of how this may also serve as a biological buffering mechanism.

192 c oxidative stress condition through a redox-buffering mechanism.

193 of gene expression requires the existence of buffering mechanisms that tightly regulate the magnitude

194 ize differences had undermined developmental buffering mechanisms.

195 ort hairpin RNAs (shRNAs) identified the ATP-buffering, mitochondrial creatine kinase CKMT1 as necess

196 and refolding of misfolded species, thereby buffering mutations that compromise protein structure an

197 The electron-buffering nitrosyl's role is subtler as a bifunctional e

198 NA)-Nkx2.1 gene duplex that is essential for buffering Nkx2.1 expression, lung epithelial cell identi

199 This also allows us to conclude that Ca(2+) buffering normally controls late release and prevents th

200 the important role astrocytic EAAT2 plays on buffering nTS excitation and overall cardiorespiratory f

201 on regime in which supramolecular ring-chain buffering occurs as well as the maximum concentration of

202 an important piece to the puzzle of how zinc buffering occurs in a large number of microbes and provi

203 l data of several molecular systems in which buffering occurs via competition between cyclization, gr

204 Our analysis shows that supramolecular buffering of a molecule is caused by its participation a

205 nate-derived buffering did not contribute to buffering of acid loads from short (</= 4 s) trains of a

206 CPu axons, and evidence for endogenous fast buffering of Ca(2+) in NAc.

207 ogical resilience was associated with marked buffering of CTRA activation such that PTSD-affected for

208 mitochondria play a major role in the rapid buffering of cytosolic calcium, we hypothesized that alt

209 ronal excitability via transporter-dependent buffering of extracellular glutamate (Glu).

210 The amplification and buffering of fire-climate relationships by humans unders

211 Mfn2 increased buffering of intracellular Ca(2+), an effect mediated th

212 Thus, we found evidence for demographic buffering of life histories, but also evidence of mechan

213 p expression in l-LNvs may contribute to the buffering of light-driven arousal in wild-type flies.

214 cts is limited, and thus there is incomplete buffering of ploidy variation despite a common cytosol.

215 (or a combination of them) provide efficient buffering of size variations.

216 t abundance, but we lack evidence of spatial buffering of temporal variability in demographic rates s

217 We therefore find evidence for spatial buffering of temporal variability in early juvenile surv

218 lation of uptake and efflux transporters and buffering of the free metal concentration by low-molecul

219 reported an organocatalytic system in which buffering of the molecular catalyst by supramolecular in

220 itutions in their substrates, likely through buffering of their destabilizing effects.

221 modification of endogenous BiP enhancing ER buffering of unfolded protein stress in mammalian cells,

222 By buffering offspring against environmental perturbation w

223 s reduced by increasing intracellular Ca(2+) buffering or by reducing Ca(2+) influx but did not appea

224 this forest but also plays a central role in buffering or exacerbating impacts of climate fluctuation

225 ner effects occur only during stress (social buffering) or generally throughout daily life (main effe

226 an be partially rescued by improving calcium buffering, or decreasing action potential-evoked calcium

227 g throughout the species' latitudinal range, buffering overall performance across a range of temperat

228 g compensatory increases in alterative redox-buffering pathways.

229 f available calcite plays a critical role in buffering pH; (3) high salinity in general hinders As re

230 side comparison of supramolecular ring-chain buffering, pH buffering, and molecular titration is pres

231 nce Ca2(+)-activated K(+) (BKCa) channels in buffering phenylephrine-induced vasoconstrictions was de

232 In addition to buffering plants from water stress during severe drought

233 Thermal buffering potential is broadly determined by: (i) the di

234 map that used the soil and hydrogeological P buffering potential of the watershed as key assumptions

235 tio of flux and [Ca2+] gradient) and SR Ca2+ buffering power (B).

236 e phagosomes of M1 macrophages had a similar buffering power and proton (equivalent) leakage permeabi

237 The buffering power, B, of the sarcoplasmic reticulum (SR),

238 The calcium buffering power, binding capacity and non-linear binding

239 s not increase the total acidity and reduces buffering power, tartaric acid shows the opposite behavi

240 mplicating RNA structural remodelling in the buffering process.

241 ed modeling revealed that the low endogenous buffering promotes fast clearance of Ca(2+) from the act

242 ion, treatment with the mitochondrial Ca(2+)-buffering protein parvalbumin significantly suppressed R

243 rin1 (CSQ1), a sarcoplasmic reticulum Ca(2+) buffering protein, inhibits SOCE, but the mechanism of a

244 In the presence of calretinin, a Ca(2+)-buffering protein, the amplitude of cytosolic spikes dur

245 Our finding of tensional buffering, rather than homeostasis, allows cells to tran

246 o affect both the Ca(2+) uptake rate and the buffering reaction, but the role of anion transport in d

247 e assembly location, providing a wide Ca(2+) buffering regime while maintaining membrane stabilizatio

248 architecture and special energy and calcium-buffering requirements at the synapse.

249 n to localized energy production and calcium buffering requirements.

250 For DBRHs, we show that buffering requires helicase activity, implicating RNA st

251 These results suggest a possible Ca(2+) buffering role for lysosomes and shed new light on lysos

252 ning of caveolae (known for their mechanical buffering role) associated with integrin diffusion and t

253 plemented-also offer water filtration, flood buffering, soil health, biodiversity habitat, and enhanc

254 ) to the pseudo-EF-hand mitochondrial SCaMCs buffering/solute transport proteins.

255 The buffering solution approach is simpler than the standard

256 on external calibration in the presence of a buffering solution containing 5 mg L(-1) Na, K, Ca, Mg a

257 accelerated Li-ion transport, and sufficient buffering space for volume change during electrochemical

258 ffering roles of species and clade ranges in buffering species from background and mass extinctions.

259 exist in continental Antarctica beyond 2099, buffering species-wide declines.

260 through undifferentiated cells by providing buffering storage for excess calcium before final excret

261 ata are informative in developing new Ca(2+) buffering strategies for the failing heart.

262 [Ca(2+) ]i transient, increased fast Ca(2+) buffering strength, shortened action potentials and redu

263 elease per [Ca2+]i transient, increased Ca2+ buffering strength, shortened action potentials, and red

264 d Ca2+ release due to an increased cytosolic buffering strength.

265 s serve very different biological functions, buffering surplus lipids for subsequent oxidation or exp

266 tion with important implications for calcium buffering, synaptic plasticity, and protein-membrane ass

267 most significantly by the cytosolic calcium buffering system and changes in diastolic Ca(2+) .

268 e glutathione pathway, an efficient cellular buffering system that counteracts reactive oxygen specie

269 parvalbumin are part of the cellular calcium buffering system that determines intracellular calcium d

270 support a model in which LDs provide a lipid buffering system that sequesters FAs released during the

271 mRNPs and establishes a post-transcriptional buffering system to facilitate SSC homeostasis in the fl

272 Our results demonstrate that distinct buffering systems are dedicated to particular Ca(2+) sou

273 e Ca(2+) transport, the intracellular Ca(2+) buffering systems expressed in ameloblasts and provides

274 emediation by providing microbially mediated buffering systems for the associated microbial and/or ch

275 t that incorporates diffusion, intracellular buffering systems, and stochastically gated ion channels

276 ation is a result of intrinsic developmental buffering that ensures phenotypic robustness under genet

277 bustness requires a process of developmental buffering that is largely not understood, but which can

278 fat storage in excess of levels optimal for buffering - that is, obesity.

279 with the silicate melt, both responsible for buffering the chlorine (Cl) concentration.

280 '-5' linkages, with the flanking nucleotides buffering the disruptive effects of the isomeric linkage

281 over were also highly protected, potentially buffering the effects of global change.

282 atically search for well individuals who are buffering the effects of rare, highly penetrant, deleter

283 racts with SES, potentially exacerbating and buffering the effects of stress, to predict anthropometr

284 tion and adaptation, acting as CO2 sinks and buffering the impacts of rising sea level.

285 O(2), neutralizing entering protons and thus buffering the periplasm to a pH of roughly 6.1 even in g

286 g the sample for 5 min, adjusting the pH and buffering the sample prior to the immunochemical analysi

287 nhancers that have opposite effects, thereby buffering their impact on enhancer activity.

288 cells that grow more than their neighbours, buffering their influence on organ size and shape.

289 upports their pluripotency, while apparently buffering them against pro-differentiation stimuli.

290 might possess inducible pesticide tolerance, buffering them from agrochemical exposure.

291 Buffering therefore distinguishes asynchronous vesicles

292 naturally occurring compound involved in the buffering, transport, and regulation of cellular energy,

293 Buffering upward arrow[Ca(2+)]i in endothelial cells doe

294 en engineering approach to improve molecular buffering using multivalent ring-chain systems.

295 vated CA1 pyramidal neuron were reduced when buffering was augmented by exogenous carbonic anhydrase

296 utations that are deleterious and subject to buffering when introduced individually into the ancestra

297 However, strong postsynaptic Ca(2+) buffering with BAPTA abolished the potentiation and sele

298 Increasing intraterminal calcium buffering with EGTA-AM or decreasing calcium influx with

299 type Ca(2+) current and blocked by strong pH buffering with HEPES or TABS.

300 lost across the Eukarya, pointing to genetic buffering within the essential NMD pathway.