ライフサイエンスコーパス: build-up of

1 rsal tongue epithelium, which results in the build up of a plaque of cell debris that severely impair

2 This route allows the build-up of a carbon lattice by a chemistry free of hydr

3 al fields and a fast, reversible, and strong build-up of a charged dye-modified lipid in the directio

4 The model describes the progressive build-up of a HA concentration polarization layer at the

5 , two or more mutations participating in the build-up of a new complex function may be required to be

6 of the ATP concentration, indicative of the build-up of a pre-steady state intermediate.

7 kinase and absence of FraB deglycase causes build-up of a toxic metabolite: 6-phosphofructose-aspart

8 olvement of alternative electron routes, the build-up of a transmembrane pH gradient and membrane pot

9 The building up of a prepotent response tendency was tested

10 on imaged at closest approach and led to the building up of a substantial and complex regolith consis

11 The capsid of herpes simplex virus is built up of a variety of proteins, and we scrutinized th

12 the evidence for a central role of cerebral build-up of Abeta in the pathogenesis of Alzheimer's dis

13 rotein misfolding disease characterized by a build-up of Abeta peptide as senile plaques, neurodegene

14 8 kinases, Hsp70 serves as a "sensor" of the build-up of abnormal proteins after heat shock and other

15 contrast to previous studies that observed a build-up of activity associated with the passage of time

16 The backbone is built up of alpha-1,6-linked mannose residues and the si

17 mospheric NMHC mole fractions coincided with build-up of ambient 1-h ozone to levels exceeding 150 pp

18 ndicating that it did not act by causing the build-up of an endogenous pathway signal.

19 thylamine oxidation suggest the pH-dependent build-up of an inhibitory intermediate, which was subseq

20 ow the H(+) into the vesicles to prevent the building up of an overwhelming electrical gradient acros

21 In experiment 2 this protocol elicited a build-up of anticipatory head and gaze velocity, in oppo

22 ential of uterine macrophages resulting in a build up of apoptotic bodies at the uteroplacental inter

23 developed early in the Archaean to prevent a build-up of atmospheric oxygen before the Proterozoic.

24 rate and perceptual phase durations; and the build-up of auditory streaming.

25 A build-up of carbon in the deep ocean has been shown to h

26 questration of Abeta1-42 was followed by the build-up of carboxyterminal fragments of the endogenous

27 ation of coordinated water molecules and the build-up of charge on the metal ion in its DPP complex b

28 Furthermore, the build up of cholesterol in NP-C lysosomes was not a phys

29 articular, DNA replication correlates with a build-up of compartments and a reduction in TAD insulati

30 The build-up of complexity in communities is theoretically d

31 s decomposition of metabolites can lead to a build-up of compounds that compete with natural enzyme s

32 not thought to have a major influence on the build-up of continental diversity.

33 isrupted magnetosome chain, and an anomalous build-up of cytoskeletal filaments between magnetosomes.

34 tions in somatic maintenance, resulting in a build-up of damage.

35 tion of mmpL10 or chp2 leads to an important build-up of DAT inside the cells and to the formation of

36 A build-up of degradative organellar by-products and decre

37 We find that the build up of diversity from a single founding strain is e

38 hibitors, which might be expected to lead to build-up of endogenous fatty acids, also activate native

39 This compound is a new lignan built up of epiphyllic acid and two isocitryl esters in

40 op in accuracy can be partly attributed to a build-up of error and ambiguity as more sequences are al

41 Build-up of excitation to reticulospinal neurons is the

42 This build-up of excitation to threshold is the key decision-

43 We hypothesize that the build-up of extracellular adenosine during theta activit

44 A build-up of extracellular K(+) in the internode and pers

45 ions in eukaryotes with implications for the build-up of extracellular matrices, retroviral infection

46 otective effect occurs despite the continued build-up of extraneuronal PrP(Sc) and continued replicat

47 a new framework to explicitly understand the building up of FC through neuronal dynamics underpinned

48 amine ferulate is a sink for the anticipated build-up of feruloyl-SCoA, and may be up-regulated in re

49 Our results show the build-up of food-web complexity in natural productivity

50 es the utilization of PCNA by inhibiting the build-up of free PCNA on DNA in the absence of polymeras

51 anic electronic device phenomena such as the build-up of functional deeply trapped charge layers in p

52 In this disease, abnormal build up of G(M1)-ganglioside in the endoplasmic reticul

53 permassive black-hole growth may precede the build-up of galaxy spheroids.

54 f the relative importance of islands for the build-up of global diversity.

55 ative phosphorylation enzymes meant that the build-up of glucose intermediates was less severe in the

56 been proposed as a method of mitigating the build-up of greenhouse gases in the atmosphere.

57 In Expt 1, the build-up of hand and eye responses was examined for targ

58 version of parvalbumin (PV.NLS-mC) led to a build-up of HDAC4 and HDAC5 in the cell nucleus, which i

59 Importantly, reversing the build-up of histone deacetylase 2 by short-hairpin-RNA-m

60 bsence of human perturbations no substantial build-up of ice sheets would occur within the next sever

61 ere we report the observation of spontaneous build-up of in-phase ('zero-state') and antiphase ('pi-s

62 different: Ca2CdSb2 has a layered structure built up of infinite layers of CdSb4 tetrahedra connecte

63 fraction of its theoretical value due to the build-up of insulating lithium peroxide (Li(2)O(2)), the

64 take place by a distributive mechanism, with build-up of intermediates observed in electrospray mass

65 toxicity disorder characterized by dramatic build-up of intracellular hepatic copper with subsequent

66 urchins held in air: 231.58 and 245.16) and build-up of its degradation products, mainly inosine (co

67 call self-driven jamming, that promotes the build-up of large mechanical pressures in microbial popu

68 results suggest that self-driven jamming and build-up of large mechanical pressures is a natural tend

69 t a property-based level of hierarchy in the build-up of larger protein structures and suggest that t

70 ective immunity could result from a retarded build-up of leukocytes around migrating lung worms and/o

71 s for both QTL, a finding which supports the build-up of linkage disequilibrium due to selection.

72 which the small number of neighbours causes build-up of local correlations between the state of adja

73 A similar lack of wyosine base and build-up of m(1)G(37) is seen in certain mammalian tumor

74 Here we show that the parallel build-up of mating incompatibilities between stickleback

75 lar homeostatic balance leading to excessive build-up of matrix in kidney.

76 The latter finding allows for the building up of mesoscale domains with spontaneous polari

77 However, biofouling, the build-up of microbes and their polymeric matrix, clogs t

78 ype of senile dementia, is associated to the build-up of misfolded amyloid-beta (Abeta) in the brain.

79 ubiquitin-proteasome system (UPS) to avoid a build-up of misfolded protein aggregates.

80 We propose that a delayed build-up of mitosis-dependent genomic DNA damage or a lo

81 red acquisition of genes and the progressive build-up of molecular mechanisms that increase virulence

82 junction (NMJ) denervation and pre-synaptic build-up of mutant GlyRS.

83 lines selected for molecular analysis; (iii) build-up of mutation load was prevented by screening Mu-

84 ng of conduction velocity in C-fibres by the build-up of Na(+) channel inactivation.

85 e accumulation within plaques, contribute to build-up of necrotic pools, and explain in part the reti

86 nts can sufficiently stabilize the resulting build-up of negative charge during Meisenheimer complex

87 2 acts as both a Lewis acid (stabilizing the build-up of negative charge upon hydride transfer from F

88 er strands to entwine, or produces extensive build-up of negative supercoils in the newly synthesized

89 ling of large diameter sensory neurons and a build-up of neurofilaments in the cell bodies and proxim

90 ects to sugar beet proteinase inhibitors and build up of non-sensitive midgut proteases.

91 erse matrix-related effect caused by gradual build-up of nonvolatile matrix components in the GC syst

92 Atherosclerosis, the build-up of occlusive, lipid-rich plaques in arterial wa

93 ssion of antioxidant defense responses, abet build-up of ozone-derived ROS and ultimately lead to oxi

94 The build-up of p21(CIP1/WAF1) and especially p27(KIP1) comm

95 Peat soils are formed by the build-up of partially decomposed organic matter under wa

96 vestments in leaf chloroplast biogenesis and build-up of photosynthetic capacity.

97 ly fits the data and accurately predicts the build-up of plasticity during random firing.

98 osphatidylinositol-4-phosphate rather than a build-up of polyphosphoinositides or changes in the acti

99 To avoid the build-up of potentially toxic intracellular protein aggr

100 ng agent dithiothreitol, which prevented the build up of Pr-SSGs in the cell, also blocked the accumu

101 he ends of each segment were overcome by the build-up of pressure in the dyke end; then a new segment

102 rarchical complexity, and revealed a gradual build up of protein repertoires associated with metaboli

103 phagy may potentially help to counteract the build-up of reactive oxygen species in cells undergoing

104 se and distant effects are attributed to the build-up of refractoriness in representations with share

105 for the rapid assembly of oligosaccharides, built up of repetitive elements.

106 al selection in speciation is to connect the build-up of reproductive isolation between populations t

107 nt the radionuclide impurity of (177m)Lu and build-up of secondary (177)Lu from the (177m)Lu decay.

108 pression control by Ldb2a enables an initial build-up of signalling via a fully active positive feedb

109 ap temperature by q=0 magnetic order and the build-up of significant dynamic antiferromagnetic correl

110 velop cognitive deficits associated with the build-up of soluble TDP-25.

111 due complementarity, redundancy, incremental build-up of specificity and conformational side chain pl

112 h pronounced charge anomalies, arises from a build-up of spin correlations, in agreement with recent

113 of Abeta1-42WT and Abeta1-42A2V peptides in building up of stable intermolecular interaction.

114 ging changes are not primarily a result of a build-up of stochastic damage but are rather a product o

115 ying of nanoparticle suspensions release the build-up of strain through a variety of different mechan

116 chemical shift analysis, which describes the build-up of structure at the level of individual residue

117 The experiments reveal a transient build-up of surface intermediates (OH(-) and Ce(3+)) and

118 articular interest because it allows for the building-up of surface covalent organic frameworks.

119 ance both of control strategies that address build-up of susceptible individuals and efforts to mitig

120 activity resulted in opposite outcomes, with build-up of Tau oligomers in enlarged auto-lysosomes.

121 with increasing chain length faster than the build-up of tertiary interactions, indicating that alpha

122 This results in a build up of the intermediate phosphatidylmonomethylethan

123 ivities in these patients concomitant with a build-up of the abiogenic 7-isomer (7BH(4)), leading to

124 Build-up of the biosensor was carefully optimized with a

125 wild type and took place without detectable build-up of the heme Fe(III)NO immediate product.

126 vivax transmission model to demonstrate the build-up of the hypnozoite reservoir following new infec

127 There is no gradual build-up of the large conformational change known to acc

128 t chain in both cell types, causing dramatic build-up of the p8 product of Cathepsin S and interferin

129 Such feedback leads to build-up of the pathway intermediate uridine monophospha

130 hesis, which posits that AD results from the build-up of the peptide beta-amyloid.

131 hanced kinase activity is facilitated by the build-up of the reduced and acetylated forms of the lipo

132 Fmoc-Nle(epsilon-N3)-OH during the stepwise build-up of the resin-bound peptide 1b.

133 Lysosomal build-up of the substrate glucocerebroside occurs in cel

134 utative pathways controlling the progressive build-up of the SV40 capsid.

135 However, the initial build-up of the thermal distribution proved difficult to

136 ompounds, like other double perovskites, are built up of the alternating sequence of corner-sharing (

137 It is built up of the linear tetrasaccharide repeating unit [3

138 us to conclude that the O-polysaccharide is built up of the tetrasaccharide repeating sequence: -->6

139 the capillary, which is responsible for the built-up of the potential at the tip, and the electrospr

140 physiological terms as a need to reduce the build-up of thermolabile metabolic intermediates that wo

141 -apoptotic form of cell death induced by the build-up of toxic lipid peroxides.

142 Here we report a build-up of trace gases over the south pole approximatel

143 in striking contrast to the slow and gradual build-up of transgenic copies during plastid transformat

144 interact with RNA, and preceded the gradual build-up of translation.

145 However, this build-up of triglyceride-rich chylomicrons/very low dens

146 r a formal representation of the progressive build-up of trust in the model.

147 and small-angle X-ray scattering, reveal the build-up of two partially folded intermediate conformati

148 n lipid degradation would likely result in a build up of undigested material in RPE that could contri

149 sponse, where cells react to the stress of a build-up of unfolded proteins in their endoplasmic retic