ライフサイエンスコーパス: bundle

1 tions of spin-label sites at the base of the bundle.

2 a remote allosteric site outside the helical bundle.

3 ed by the restoring force of the microtubule bundle.

4 pathway to traffic Tmc proteins to the hair bundle.

5 lacement of the first helix in the six-helix bundle.

6 inct conformational changes within the helix bundle.

7 m guidelines using the evidence-based ABCDEF bundle.

8 e contralateral parahippocampal white matter bundle.

9 er installations as the focus of our hygiene bundle.

10 T complex proteins can still localize to the bundle.

11 mit, and rarely the LVOT septum near the His bundle.

12 irm that the Tsr HAMP maintains a four-helix bundle.

13 e failure of Pcdh15a to localize to the hair bundle.

14 cesses and reduced numbers of C-fibers/Remak bundle.

15 fficking of other MET components to the hair bundle.

16 ospital mortality and compliance with 6-hour bundle.

17 f functional stereocilia within a given hair bundle.

18 f cell-intrinsic signals that shape the hair bundle.

19 ) with stronger lateral interactions remains bundled.

20 th motile arms on both microtubules, produce bundles.

21 gle microtubules, stable bundles, or dynamic bundles.

22 elongated, and distributed between collagen bundles.

23 alently crosslink actin filaments into tight bundles.

24 he electrospun fibers to merge into multiple bundles.

25 ss spacing and haphazard actin microfilament bundles.

26 flow across rows of differently shaped hair bundles.

27 peptide assembly into parallel-aligned fiber bundles.

28 so by elastic stress in the peripheral actin bundles.

29 minescence microscope throughout the nanorod bundles.

30 t govern their assembly into dense hexagonal bundles.

31 r helical domains organized into two helical bundles.

32 ed FtsZ assembly and caused the filaments to bundles.

33 in a higher preferential formation of fiber bundles.

34 itherto not appreciated role for microtubule bundling.

35 arate also led to dysregulation of FtsZ ring bundling.

36 calization (%ARNL) and increased microtubule bundling.

37 t turnover in WT is not sufficient to induce bundling.

38 d repeat (NHR) trimer and blocking six-helix-bundle (6-HB) formation.

39 he capacity of other formins to nucleate and bundle actin filaments but is notably less effective at

40 determined that Fhod binds the sides of and bundles actin filaments.

41 ins of TPX2 contribute to its MT-binding and bundling activities.

42 module controls the timely localization and bundling activity of Mklp2 at the anaphase central spind

43 TmeA also impairs AHNAK-dependent actin bundling activity.

44 al modeling showed that an optimal amount of bundling agents enhanced the ability of a network to con

45 ration protein, which, with just a six-helix bundle and a six-stranded beta-sheet, forms a genome-del

46 self-assembles into a hexameric coiled-coil bundle and an Fc-binding Protein A fragment, we generate

47 nce with the Surviving Sepsis Campaign (SSC) bundle and appropriateness of initial antibiotic therapy

48 lizing apical actin structures like the hair bundle and ensuring that the apical membrane forms appro

49 e C112R substitution in the N-terminal helix bundle and likely relate to a reduced ability of apoE4 t

50 ween the time until completion of the 3-hour bundle and risk-adjusted mortality.

51 of a cross-linked actomyosin network into a bundle and the buildup of tension occurring during the t

52 fimbria-fornix, parahippocampal white matter bundle and uncinate fasciculus were reconstructed, and s

53 We also model the formation of fiber bundles and domains so that we explore the mechanism tha

54 ated at the interface between actin filament bundles and dynamic MTs in filopodia, suggesting that ta

55 y alpha-helical lids, to multi-alpha-helical bundles and layers.

56 otal role for SUMOylation in septin filament bundling and cell division.

57 MRS2500 (orthosteric, contacting the helical bundle) and urea BPTU (allosteric, on the external recep

58 ance during stress treatment and could bind, bundle, and stabilize microtubules in vitro.

59 the ipsilateral parahippocampal white matter bundle, and the ipsilateral fimbria-fornix in regions lo

60 r, acetylated microtubules are predominantly bundled, and bundling enhances kinesin run lengths and p

61 ary interstitium, loss of medullary vascular bundles, and decreased urine concentrating ability.

62 tograms contain many more invalid than valid bundles, and half of these invalid bundles occur systema

63 erhelical loops of the C-terminal four-helix bundle appear to penetrate the membrane bilayer, stabili

64 and Ptk7 In wild-type mice, collagen-fibril bundles appear within a tectorin-based matrix at E15.5 a

65 accessible sites at the opposite end of the bundle are occupied last.

66 The TEM/HRTEM results confirm that these bundles are composed of several individual nanorods with

67 Bundles are polymerized from the surface of mDia1-coated

68 Stress fibers-contractile actomyosin bundles-are important for cellular force production and

69 neurite density, rather than aberrant fiber bundle arrangement (orientation dispersion index).

70 works alternate between single filaments and bundled arrays under the influence of effectors controll

71 trometry (CFI-MS), which uses a carbon fiber bundle as the ion source, is useful for the analysis of

72 ticipants demonstrated inclusion of the four bundles as intended, matching the connectome blueprint p

73 ntial use of such emerging dual mode nanorod bundles as photon sources for next generation flat panel

74 chitecture is dominated by contractile actin bundles attached at their ends to large, stable, integri

75 At short times, the bundle behaves as an elastic material, whereas at long t

76 ronization Therapy) study patients with left bundle branch block (LBBB) and 0, 1, 2, or >/=3 comorbid

77 In contrast to patients with left bundle branch block (LBBB), heart failure patients with

78 aventricular tachycardia with aberrant right bundle branch block (RBBB) and left anterior hemiblock (

79 rietal band VAs were characterized by a left bundle branch block and left inferior (n=12) or superior

80 as applied in the presence of complete right bundle branch block by atrial-synchronized RV free wall

81 P<0.001) along with elimination of the right bundle branch block QRS morphology, increase in RV filli

82 pidemia, and had more often a non-LBBB (left bundle branch block) wide QRS complex, and lower left ve

83 ents with congenital heart disease and right bundle branch block, RV cardiac resynchronization therap

84 New-onset left bundle-branch block and the need for permanent pacemaker

85 The MB-LATER score (Male, Bundle brunch block, Left atrium >/=47 mm, Type of AF [p

86 ata from hexagonal arrays, revealing how the bundle bulk modulus and the deflection length of filamen

87 tension were decreased in heterozygous fiber bundles, but increased in homozygous fiber bundles compa

88 The ESRD Prospective Payment System bundling, but not the training add-on, associated with s

89 nshift Y1.94O3:Ho(3+)0.02/Yb(3+)0.04 nanorod bundles by a facile hydrothermal route has been introduc

90 ven severe dysmorphogenesis of stereociliary bundles can be corrected.

91 rimental results suggest that multiple fiber bundles can be formed under the condition of a low teeth

92 o demonstrate that these piezoelectric fiber bundles can serve as ultra-flexible textile sensors.

93 s that Aurora contributes to the microtubule bundling capacity of MAP65-1 in concert with other mitot

94 ioinks from a single printhead consisting of bundled capillaries synergized with programmed movement

95 the internal capsule, the white matter (WM) bundle carrying ascending and descending fibers from the

96 ular zone neuroblasts are aligned in tightly bundled chains within a meshwork of astrocytes; however,

97 zone consisting of anti-parallel microtubule bundles coated with chromosome passenger complex (CPC) a

98 We found that tumor cells adjacent to bundled collagen had a preferential persistence in respo

99 tient-centred pressure ulcer prevention care bundle compared to standard care.

100 r bundles, but increased in homozygous fiber bundles compared to wildtype mice.

101 reased propensity to form long multifilament bundles compared with wild type (WT).

102 Among patients who had the 3-hour bundle completed within 12 hours, a longer time to the c

103 nd free of delirium and coma with both total bundle compliance (incident rate ratio, 1.02; 95% CI, 1.

104 2; 95% CI, 1.01-1.04; p = 0.004) and partial bundle compliance (incident rate ratio, 1.15; 95% CI, 1.

105 2.67; CI, 1.74-4.09), initial 3-hour sepsis bundle compliance (odds ratio, 1.57; CI, 1.07-2.30), and

106 to determine the association between ABCDEF bundle compliance accounting for total compliance (all o

107 ween hospital characteristics and prevention bundle compliance and changes in MDRO infection rates.

108 ns were instructed to collect data on 6-hour bundle compliance and outcomes in patients with sepsis i

109 was to study the association between ABCDEF bundle compliance and outcomes including hospital surviv

110 h differences in early goal-directed therapy bundle compliance or hemodynamic goal achievement.

111 These changes occur without altering hair-bundle compliance or the number of functional stereocili

112 In three independent cohorts, 3-hour bundle compliance was associated with improved survival

113 Higher bundle compliance was independently associated with impr

114 Total and partial bundle compliance were measured daily.

115 c pressure, mean arterial pressure, lactate, bundle compliance, amount of fluid administered, and hem

116 Likewise, for every 10% increase in partial bundle compliance, patients had a 15% higher hospital su

117 For every 10% increase in total bundle compliance, patients had a 7% higher odds of hosp

118 ohort 3: 7,239 total patients; 2,115 (29.2%) bundle compliant.

119 ohort 1: 5,819 total patients; 1,050 (18.0%) bundle compliant.

120 also sometimes positive, slopes depending on bundle composition.

121 Scattering data from aligned flagellar bundles confirmed the theoretically predicated structure

122 se and CPPase are located within a six-helix bundle containing amino acids 53 to 241.

123 nstitution-specific use of 1) a "recognition bundle" containing a trigger tool for rapid identificati

124 The care bundle cost AU$144.91 (95%CI: $74.96 to $246.08) more pe

125 cytoplasmic ends of the S6 segments (the S6 bundle crossing) at a conserved Met residue.

126 hannels is not predominantly gated by the S6 bundle crossing.

127 n their permeation pathway: one formed by a 'bundle-crossing' at the intracellular entrance and a sec

128 nd the deflection length of filaments in the bundles depend on the applied osmotic stress.

129 n during childhood and adolescence, as fibre bundles develop and myelinate.

130 reater compliance with the MDR-AB prevention bundle did not lead to reductions in MDR-AB rates.

131 Stalled abducens nerve bundles did not reach the orbit, resulting in secondary

132 Defects in this complex cause stereociliary bundle disorganization and hearing loss.

133 e changes generated by stimuli at their hair bundles drive the cell body and, in turn, it has been as

134 Bundle elements are as follows: 1) blood cultures before

135 for partial compliance ("dose" or number of bundle elements used) and outcomes of hospital survival

136 High compliance (3-6 bundle elements) and low compliance (0-2 bundle elements

137 3-6 bundle elements) and low compliance (0-2 bundle elements) had a risk-adjusted SSI rate of 8.2% (9

138 microtubules are predominantly bundled, and bundling enhances kinesin run lengths and provides a gre

139 ws covalent capture of the aligned nanofiber bundles, enhancing their birefringence and structural in

140 These luminescent nanorod bundles exhibit strong green emission at 549 nm upon exc

141 uding descending inhibitory medial forebrain bundle fibers, induces both feeding and reinforcement, a

142 are protein modules adopting conserved helix bundle folds.

143 and Medicaid Services to expand the payment bundle for renal dialysis services and legislated that p

144 otypic connectome of converging white matter bundles (forceps minor, uncinate fasciculus, cingulum an

145 T6 and SEPT7 groups leads to aberrant septin bundle formation and defects in cytokinesis after furrow

146 t this altered activity does not account for bundle formation, as reducing protofilament turnover in

147 ors indicate that the central trihelical TM2 bundle forms the intrinsic transmembrane channel of P2X

148 acing the loops and helices of the six-helix bundle from enzyme with those from the other.

149 We find that rows of V-shaped hair bundles have a considerably reduced resistance to crossf

150 In the era of bundled health care payment, strategies should be implem

151 across the proximal end of a coherent fibre bundle; high-frequency ultrasound (156% fractional bandw

152 ol practices, and compliance with prevention bundles impacted multidrug-resistant organism (MDRO) inf

153 region of the mechanosensitive stereociliary bundle in hair cells.

154 A colectomy perioperative care bundle in Michigan is associated with improved value of

155 olalpha, p261C of Pol contains a three-helix bundle in the middle and zinc-binding modules on each si

156 eins are specifically excluded from the hair bundle in tomt mutants, whereas other MET complex protei

157 is released under an open source license and bundled in a dependency-free container for wide distribu

158 PP5 expression was also increased in the ASM bundles in endobronchial biopsies in severe asthmatics.

159 milling dynamics of membrane-associated FtsZ bundles in reconstituted systems, as well as the recentl

160 hanotransduction channels at the tip of hair bundles in sensory hair cells.

161 rect result of the alignment of carbon fiber bundles in the microscale which we predict will ultimate

162 ia coli, FtsA antagonizes FtsZ protofilament bundling in vivo.

163 growth factor beta-positive cells within Asm bundles, in addition to lower numbers of chymase-positiv

164 er ZapA nor ZauP influenced FtsZ dynamics or bundling, in vitro, however.

165 the eigth period, compliance with the 6-hour bundle increased from 13.5% to 58.2% in the private inst

166 by stabilizing the midcell Z-ring through a bundling-independent mechanism.

167 Hair bundles initially developed normally, but the cell's api

168 wo incentives to increase home dialysis use: bundling injectable medications into a single payment fo

169 Over 90% of studies implemented a bundled intervention.

170 embled into microfibrils that are frequently bundled into macrofibrils.

171 mechanical parameters and confirms that the bundle is composed of weakly coupled filaments.

172 Furthermore, we find that the bundle is solid, and stiff to bending, along the long ax

173 One example of contractile bundles is a transverse arc that forms via actomyosin-dr

174 f the five Cu(I) sites at the opening of the bundle lags behind the main core, and the two least acce

175 find that imbalances in regulation of actin bundling lead to chaotic spatial patterns that could imp

176 n-coupled receptor V1 (adgrv1), another hair bundle link protein, the entry of Cdhr23- and Cdhr15-exp

177 We find that FtsZ forms bundles made of loosely bound filaments of variable leng

178 tic skills, an explanation of how this fiber bundle may support language abilities is still missing.

179 visco-elastic model allows us to extract the bundle mechanical parameters and confirms that the bundl

180 re preferentially associated with peripheral bundled microtubules.

181 cient mice develop normal rootlets, but hair bundle morphology and mechanotransduction are affected b

182 hat alpha-actinin-1 puncta within actomyosin bundles move more quickly than the paxillin-rich adhesio

183 iments with human tau expression restored MT bundling, MT penetration into the growth cone periphery

184 illary muscle (n=3; 3.1%), and apical-septal bundle (n=1; 1.0%), as well as imaging plane obliquity (

185 tient-centred pressure ulcer prevention care bundle (n=799) or standard care (n=799).

186 vivo findings indicated that abnormal actin bundles, not elongated thin filament length, were the ca

187 han valid bundles, and half of these invalid bundles occur systematically across research groups.

188 Actin bundling occurs due to simultaneous binding of both ABDs

189 he last 36 residues at the C-terminus form a bundle of five alpha-helices co-linear with the five-fol

190 ts not only an individual object, but also a bundle of objects that are grouped based on prior knowle

191 Assembly of the mechanically sensitive hair bundle of sensory hair cells requires growth and reorgan

192 More rapid completion of a 3-hour bundle of sepsis care and rapid administration of antibi

193 The design is based on a flexible fibre bundle of six multimode optical fibres, each terminated

194 on, from multilayered 2H-MoTe2 to a parallel bundle of sub-nanometer-diameter metallic Mo6 Te6 nanowi

195 applies a squeezing force on the microtubule bundle of the axons.

196 ring the expansion phase results in parallel bundles of actin filaments and myosin motors, generating

197 horter row stereocilia overgrow in hair cell bundles of both Cib2 mutants.

198 nt trends directing value-based payments for bundles of care advance the imperative for radiology pro

199 M10(Full)LZ moves on filopodial actin bundles of cells with a mean step size ( 36 nm), similar

200 collagen in the ECM is organized into large bundles of fibrils, or collagen cables, and the number o

201 n different actin filaments within the actin bundles of filopodia.

202 While hair bundles of inner hair cells are of linear shape, those o

203 They contain parallel bundles of microtubules as structural backbones, surroun

204 prepared and found to crystallize by forming bundles of millimeter-long Au25 polymers.

205 hat the biologically observed shapes of hair bundles of outer hair cells are near-optimal in this reg

206 the size found in solution for alpha-helical bundles of peptides with a similar amino acid sequence.

207 sposition to stretch-induced damage in fiber bundles of R349P mice.

208 r, densely packed mineral layers, comprising bundles of small needle-like HA crystals, formed on etch

209 ys the frequency of repeated choices between bundles of two liquids.

210 urons into clusters, local connectivity, and bundling of long-range axons.

211 abnormalities, specifically accumulation and bundling of perikaryal and dendritic neurofilaments.

212 nd septic shock focused on the resuscitation bundle on 90-day mortality.

213 etwork organization varied from long, linear bundles, or "fibers," to shorter fragments with a mesh-l

214 izations: stable single microtubules, stable bundles, or dynamic bundles.

215 ccurs concomitantly with a transition in the bundle orientational order near the surface and is contr

216 s, and two sibling HCs develop opposite hair bundle orientations.

217 but shifted posteriorly, with adjacent fiber bundles overlapping minimally.

218 observed at the right atrium and Bachmann's bundle (P<0.001).

219 Permanent His-bundle pacing has emerged as the leading candidate for p

220 ive techniques such as multisite pacing, His bundle pacing, and endocardial left ventricular pacing.

221 pacing options, with particular focus on His-bundle pacing.

222 tocols appear well aligned with the goals of bundled payment initiatives for surgical episodes.

223 iwan, compared with the regular FFS program, bundled payment may lead to better adherence to quality

224 s Data, the National Death Registry, and the bundled-payment enrollment file.

225 s 0 to III breast cancer were 84.48% for the bundled-payment group and 80.88% for the FFS group (P <

226 Although the 5-year medical payments of the bundled-payment group remained stable, the cumulative me

227 nsitivity analysis for bonus payments in the bundled-payment group was also performed.

228 ical payments (excluding bonuses paid in the bundled-payment group).

229 In the bundled-payment group, 1473 of 4215 patients (34.9%) wit

230 Patients in the bundled-payment program were matched at a ratio of 1:3 w

231 0 to $19230 and exceeded pay-for-performance bundled payments starting in 2008.

232 To assess the value of bundling perioperative care measures in colon surgery.

233 Through stabilization of such bundles, plastins contribute, in an isoform-specific man

234 Downstream effectors of Emx2 control bundle polarity cell-autonomously via heterotrimeric G p

235 ing the sound-induced movement of their hair bundles present at the top of these cells, into an elect

236 We conclude that myosin drives actomyosin bundle production and that myosin activity is tightly re

237 Bundle properties are strikingly different from the ones

238 lymerization protein) and palladin (an actin bundling protein).

239 og families, including small GTPases, coiled-bundle proteins, and proteins with beta-propeller and al

240 N-terminal head and a C-terminal five-helix bundle (R9).

241 ography, we describe novel methods for fiber bundle reconstruction and graph-based connectivity analy

242 ational changes in a C-terminal four-helical bundle region of ExoU as it interacts with lipid substra

243 As prospective payment transitions to bundled reimbursement, many US hospitals are implementin

244 een phases of compression and extension, the bundle reinforces.

245 ual force buildup while parallel microtubule bundles remain stationary with a small amount of antagon

246 t tau's ability to induce stable microtubule bundles requires two hexapeptides located in its microtu

247 ow in the longitudinal direction, leading to bundle restructuring.

248 dicaid Services adopted the Early Management Bundle, Severe Sepsis/Septic Shock (SEP-1) performance m

249 G molecular species, among mesophyll (M) and bundle sheath (BS) cells, are compared across the leaf d

250 tricted to developing leaf veins, to include bundle sheath cells encircling the vein.

251 HSS has been localized in the bundle sheath cells of specific leaves.

252 n the chloroplasts of mesophyll (C3 plants), bundle-sheath (C4 plants), and guard cells.

253 ecessary for final stabilization of the hair bundle.SIGNIFICANCE STATEMENT Assembly of the mechanical

254 Swellix bundles similar helices and includes improvements in mem

255 Actomyosin bundle size, connectivity, spacing, and orientation are

256 By contrast, rigid filament bundles slide without bending under motor stress, yieldi

257 variants support a biphasic model of dynamic bundle stability, but also indicate distinct conformatio

258 open, the tip links relax, reducing the hair-bundle stiffness.

259 The bundle stoichiometry in the mesophase agrees well with t

260 We found that ZipA not only stabilized and bundled straight filaments of FtsZ-GTP, but also stabili

261 Contractile actomyosin bundles, stress fibers, are crucial for adhesion, morpho

262 ad-repeat regions refold to form a six-helix bundle structure that can be specifically targeted by fu

263 ular target membrane and forming a six-helix bundle structure.

264 3C proteins do not form classical four-helix-bundle structures as was initially predicted.

265 lus recognition is mediated via a four-helix bundle subdomain located in the cytoplasm, which functio

266 changes of chemical components on the fiber bundle surface during the process, indicating that FTIRM

267 sin contraction, and actin polymerization at bundles' terminals when the product of MRCKalpha cleavag

268 led the complete structure of the four-helix bundle that forms the C-terminal domain.

269 model the formation of the SNARE four-helix bundle that mediates synaptic vesicle fusion and used it

270 ngly, several thinner fibrils formed ordered bundles that either covered the surfaces of proteoliposo

271 Cells assemble numerous types of actomyosin bundles that generate contractile forces for biological

272 ery (ERAS) protocols are evidence-based care bundles that reduce morbidity.In this study, we compared

273 HAMP domains are dimeric, four-helix bundles that transduce conformational signals in bacteri

274 st of a series of four-transmembrane helical bundles that we term Piezo repeats.

275 ted teeth on the formation of multiple fiber bundles, three-dimensional finite element simulations ar

276 designed to engage strategically the ABCDEF bundle through team- and evidence-based care.

277 romotes generation of contractile actomyosin bundles through synchronized NM-II folding and filament-

278 intracellular end of this helix, opening the bundle to accommodate interactions with the alpha5-helix

279 (SNARE) proteins into a parallel four-helix bundle to drive membrane fusion.

280 water-soluble self-assembled foldamer helix bundle to encapsulate simple guest molecules within an i

281 that even relatively weak attraction causes bundles to appear, while if axons weakly repulse each ot

282 at M10(Full)LZ meandered on filopodial actin bundles to both x- and y- directions.

283 roteins use amphipathic helical layering and bundling to form modular lipid-binding compartments and

284 actograms containing 90% of the ground truth bundles (to at least some extent).

285 shock, 2) a "resuscitation and stabilization bundle" to help adherence to best practice principles, a

286 t practice principles, and 3) a "performance bundle" to identify and overcome perceived barriers to t

287 ours, a longer time to the completion of the bundle was associated with higher risk-adjusted in-hospi

288 In the cost-effectiveness analysis, the care bundle was estimated to cost an additional $3296 (95%CI:

289 The evidence-based ABCDEF bundle was successfully implemented in seven community h

290 Correlated activity in muscle bundles was linked with early twitching and eventual coo

291 First, ZipA-induced FtsZ bundling was not significant at pH greater than 7.

292 s instead associate with lateral microtubule bundles; whether errors can be sensed in this context is

293 ased FA in multiple major white matter fiber bundles, which connect the fronto-parietal control netwo

294 end domains to allow filament compaction and bundling, whilst also retaining extensibility to ensure

295 oride-trifluoroethylene) piezoelectric fiber bundles with a controlled separation.

296 iB1 reveals that Wbl proteins are four-helix bundles with a core of three alpha-helices held together

297 We noted the presence of abnormal Remak bundles with long SCs processes and reduced numbers of C

298 Microtubule network densification and bundling, with the transient formation of an array of co

299 aments and developed abnormal actin filament bundles within sarcomeres that interconnected Z lines an

300 esidues on the exterior of the alpha-helical bundle yields monodisperse macromolecules with programma