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1 utility caused by daily medication use (pill burden).
2 Further, trazodone reduced p-tau burden.
3 sk factors, but high infectious inflammatory burden.
4 accurate volumetric quantification of plaque burden.
5 d comparable immune-reconstitution and viral burden.
6 ancer risk, and an unnecessary psychological burden.
7 cation did not seem to match epidemiological burden.
8 STAT4-dependent manner to limit early viral burden.
9 RG1(+) ILC-2 cell number and reduced disease burden.
10 rgeting private events in reducing the tumor burden.
11 fy treatment algorithms and reduce treatment burden.
12 istosomiasis in patients with a low parasite burden.
13 stically significant improvements in symptom burden.
14 d not require a high intracellular bacterial burden.
15 nce between T-cell reinvigoration and tumour burden.
16 ere, by reducing etiology-specific diarrheal burden.
17 ation cost concerns, and perceived financial burden.
18 s the second largest cause of global disease burden.
19 isability, with a considerable socioeconomic burden.
20 its expression can be accommodated with less burden.
21 strongylus brasiliensis, increasing parasite burden.
22 al knowledge to help to counter some of this burden.
23 d by both polygenic and clinical risk factor burden.
24 nical trials to reduce disparities in cancer burden.
25 preserves IgM levels, and reduces bacterial burden.
26 crease the global atmospheric greenhouse gas burden.
27 estimates might have underestimated disease burden.
28 eters for quantification of whole-body tumor burden.
29 n America and is becoming a worldwide health burden.
30 n reversing the continuing increases in this burden.
31 reads- that cause significant computational burden.
32 lmonids, constituting a significant economic burden.
33 ribute substantially to Lesch-Nyhan syndrome burden.
34 ed to increased pathological alpha-synuclein burden.
35 de vaccine status, to predict future disease burden.
36 cular risk, represents a major public health burden.
37 d is a leading contributor to global disease burden.
38 contributors to the excess total cumulative burden.
39 assification accuracy and high-computational burden.
40 isk of perceiving donation-related financial burden.
41 a mechanism for altering tissue-specific Se burdens.
42 n, which correlated with increased bacterial burdens.
43 soriasis had increased total coronary plaque burden (1.22+/-0.31 versus 1.04+/-0.22, P=0.001), NCB (1
44 hest death rate (>35%) and per-case economic burden ($3.3 million) of any foodborne pathogen in the U
45 etastatic protein expression) and metastatic burden, accompanied with TAM polarization away from the
48 RV decompression have a high reintervention burden although most achieve 2-ventricle circulation.
53 ately 40% in countries with a high infection burden and 12% and 7% in countries with moderate and low
54 use (IDU) is a substantial cause of disease burden and a contributor to blood-borne virus transmissi
55 ting facilities, may reduce the private cost burden and achieve high emission reductions, especially
57 a significant reduction of cerebral amyloid burden and BACE1 accumulation in dystrophic neurites in
60 s, how the immune response controls parasite burden and contributes to tissue damage, and what mechan
67 h resulted in prolonged elevations in fungal burden and histopathologic evidence of chronic lung infl
68 cted neutropenic lung correlated with fungal burden and hyphal length but not induction of GT biosynt
69 ught to evaluate the prevalence of financial burden and identify associations between a higher percen
71 erapies for CTCL may variably decrease tumor burden and improve quality of life, but offer limited ef
72 g of il1beta, results in increased bacterial burden and less infiltration of macrophages to sites of
73 cal management of HF that can reduce disease burden and may help improve clinical outcomes in this vu
75 AML patient-derived xenografts reduced tumor burden and prolonged overall survival without affecting
77 fected IL-21R KO mice had enhanced bacterial burden and reduced infiltration of Ag-specific T cells i
78 llows for a better understanding of the true burden and seasonality of disease that is essential to p
79 a reduction of PID frequency and overall PID burden and showed increased neuronal survival after stro
81 e of the method used to determine metastatic burden and statistical analysis of the results, as well
84 rformance, increased CDR-SOB, higher amyloid burden and worse clinical progression (6.2 times higher
85 fficient to significantly increase bacterial burdens and kidney pathology in mice infected with MRSA.
86 applied GBD methods to generate estimates of burden, and attributable burden due to known risk factor
89 xolitinib showed reduction of mutated allele burden, and ruxolitinib might extend survival of patient
90 asm 15-year cumulative incidence, cumulative burden, and standardized incidence ratios for subsequent
91 ted symptom onset, higher global Abeta brain burden, and with lower delayed total recall scores in th
92 whereas their depletion led to higher tissue burdens, and CD8(-/-) mice displayed higher mortality wi
94 of childhood cancer may experience financial burden as a result of health care costs, particularly be
95 irus, represent a considerable global health burden, as recognised by WHO's Battle against Respirator
96 the potential for addiction is a significant burden associated with pain management, yet its precise
98 use concentrations in food to determine body burdens based on individual or population characteristic
99 40; P = .005), but not inferior temporal tau burden (beta = 0.10; 95% CI, -0.08 to 0.28; P = .27).
100 0.35; 95% CI, 0.19-.52; P < .001) and Abeta burden (beta = 0.24; 95% CI, 0.08-.40; P = .005), but no
101 ated with increasing entorhinal cortical tau burden (beta = 0.35; 95% CI, 0.19-.52; P < .001) and Abe
103 ients with an ID consult had a higher fungal burden but a lower 90-day mortality compared to patients
104 relationships are weakly related to amyloid burden, but are in part mediated by grey matter volumes.
108 ith the recombinant protein reduced parasite burdens by 76% to >99% in comparison to a variety of dif
110 tau pathology, suggesting that increased tau burden cannot fully account for the effects of LC degene
111 n models were constructed for each infection-burden category to identify independent determinants of
115 , benefits) and undesirable (i.e., harms and burdens) consequences, patient values and preferences, c
125 -718 expression is associated with bacterial burden during Neisseria gonorrhoeae infection and alters
126 reduction of the KIT D816V expressed allele burden (EAB) at month 6, patients were classified as KIT
128 estigate whether whole-liver enhancing tumor burden [ETB] can serve as an imaging biomarker and help
134 explore ecological determinants of clinical burdens from C difficile infections and ribotype distrib
136 ial distribution of Plasmodium vivax malaria burden has evoked enormous concern among the global rese
137 igh prevalence of anemia and related disease burden have been documented in China, limited evidence i
139 mice resulted in reduced morbidity and viral burden, improved lung compliance, and increased CD8(+) T
140 s of the within-host dynamics of plasma ZIKV burden in a nonhuman primate model, allowing for charact
141 of cases of disease and significant economic burden in affected areas, no licensed vaccines or antivi
146 h was accompanied by a reduced mycobacterial burden in lung and spleen and a prolonged overall surviv
147 more severe immunopathology, enhanced viral burden in multiple organs, and suppression of MCMV-speci
153 prior work documenting increased L1 genetic burden in the brains of PDS and also identify unique gen
156 s that constitute the greatest public health burden in the United States, including obesity, hyperten
157 ntries is needed, and the infectious disease burden in these countries is another reason to step up g
158 pare themselves to prevent additional health burdens in the context of a changing climate and socioec
160 se data indicate that the enhanced bacterial burdens in Tpl2(-/-) mice are not caused primarily by im
161 gly associated with coronary atherosclerotic burden (increase [95% confidence interval] in rank of pl
163 Lipid burden was assessed as the lipid core burden index (LCBI), and large LRP were defined as a max
164 who also have intellectual disability, this burden is concentrated in risk genes associated with neu
166 Ds and epigenetic marks, as tumor mutational burden is known to be coupled to chromatin structure, we
168 nual income) and issues related to financial burden (jeopardizing care or changing lifestyle) among s
169 ust incorporation of numerical metastatic LN burden may augment staging and better inform adjuvant tr
170 ge in Botswana, there is still a substantial burden of advanced HIV, with 2013-2014 incidence of CM c
174 To assess the patient-level and societal burden of atopic dermatitis, we comprehensively reviewed
175 here has been increasing focus on the rising burden of atrial fibrillation (AF) since the turn of the
178 on-based epidemiological study to assess the burden of behavioural and emotional problems in preschoo
179 come measures, clear evidence shows that the burden of behavioural risk factors is affected by socioe
180 equity, and women's cancers, we describe the burden of breast and cervical cancer, with an emphasis o
181 TNBCs and stem cells as they pertain to the burden of breast cancer among African-ancestry populatio
183 iovascular disease event types to the excess burden of cardiovascular disease is important for develo
184 Although reduced cardiac output and high burden of cardiovascular risk factors are the prevailing
186 omplication of an infection, has the highest burden of death and medical expenses in hospitals worldw
187 reasing incidence will contribute to reduced burden of dementia given the aging of the population is
189 ensive framework for estimating the economic burden of dengue in any region, differentiated by four v
196 udy data and methods, we also quantified the burden of disease related to high body-mass index (BMI),
199 ins a global health problem with an enormous burden of disease, estimated at 10.4 million new cases i
200 jury incidence and prevalence to measure the burden of diseases and injuries in Japan and in the 47 J
201 rapid increase in the prevalence and disease burden of elevated BMI highlights the need for continued
202 nding can help improve interpretation of the burden of febrile illness and shape policy on fever case
207 ide the first comprehensive estimates of the burden of group B Streptococcus (GBS), including invasiv
210 t life expectancy and trends in the residual burden of HIV mortality after the roll-out of a public s
214 nervation (CSD) has been shown to reduce the burden of implantable cardioverter-defibrillator (ICD) s
219 have led to dramatic declines in the global burden of measles, but the virus remains persistent in m
220 40-65 years in Taiwan, we associated a high burden of metabolic risk factors with increased risk of
222 between socioeconomic status and increasing burden of mortality from non-communicable diseases is li
230 ivariate regression analysis to estimate the burden of RSV in children younger than 5 years in Englan
232 across all traits (FWERacross), an increased burden of singleton disruptive variants in the Regulome
235 ere highest in foliage, while the total tree burden of summation operator26PFASs per tree was up to 1
237 dress potential overtreatment can reduce the burden of surgical management in patients with cancer.
239 y reflected the disproportionate demographic burden of TB among the population of adult males as a wh
241 oved by considering the underlying infection burden of the population and by assessing the overlap of
245 ing these findings, they illustrate that the burden of work for physicians and nurses in general prac
246 h-care inequalities and reduce the financial burdens of medical care borne by non-wealthy Americans.
247 he quantitative assessment of skeletal tumor burden on bone scintigraphy (Bone Scan Index [BSI]) in p
251 ericas and South Pacific poses a significant burden on human health because of ZIKV's neurotropic eff
254 cy in endothelial autophagy increased plaque burden only in the atheroresistant areas exposed to high
255 tatistically significant difference in tumor burden or survival distributions compared to treatment w
257 ng and robust measurements of changes in tau burden over time for the evaluation of putative therapie
258 uppression of IDO activity reduced bacterial burden, pathology, and clinical signs of TB disease, lea
262 treatment increased lesion size and parasite burden, quantitatively reproducing the LRV1-bearing (Lgy
263 a genetic threshold may exist where mutation burden relates to visual phenotype and the presence of h
267 luciclovine avidity reflect changes in tumor burden resulting from treatment has not been shown.
270 ty risk, nutrient availability, and pathogen burden shape energy allocation strategies throughout the
271 mation of pediatric MDR-TB, we surveyed high-burden states for clinically diagnosed cases treated for
275 and compare investment with national disease burden to identify areas of funding strength and potenti
276 hnic and regional differences, high exposure burden to multiple allergens was most consistently assoc
278 more likely than donors who did not perceive burden to rent their home (57% vs. 16%, P = .03), have a
279 gies generated frequent alarms that placed a burden upon staff, but staff were able to use their cont
280 These findings were translated into health burdens using a dose-response curve generated from a sys
281 ion and perturbs central metabolism and this burden varies with the protein being overexpressed.
289 opulation calibrated to pretreatment disease burden, we identify a clinically accessible potential on
290 ors who perceived donation-related financial burden were less likely to have an income above their ZI
292 e evident as a small subset of overall tumor burden, were not affected by beta-catenin suppression.
293 of ZIKV-immune CD8(+) T cells reduced viral burdens, whereas their depletion led to higher tissue bu
294 hain PFAAs substantially increase human body burdens, which remain elevated for many years after expo
295 pose a considerable world-wide public health burden with incidence as high as one in ten in 12-month-
299 hermore, most estimates of influenza disease burden worldwide rely on passive sentinel surveillance a
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