ライフサイエンスコーパス: bursting

1 rlies enhancer function and transcriptional 'bursting'.

2 ted during exponential phase with no sign of bursting.

3 e expression, largely due to transcriptional bursting.

4 aused by the rescue of anx1 anx2 pollen tube bursting.

5 mutants display spontaneous PT and root-hair bursting.

6 -4 h after the induction of action potential bursting.

7 ng neuronal firing at frequencies typical of bursting.

8 wo forms of output: tonic spiking and phasic bursting.

9 increases in both single spike frequency and bursting.

10 the rhythm and replaced it by slow unstable bursting.

11 d both drugs changed the temporal pattern of bursting.

12 increases in both single spike frequency and bursting.

13 mly, with the resultant rounded cell finally bursting.

14 we evoked brief periods (20 min) of rhythmic bursting.

15 tein-level stochasticity and transcriptional bursting.

16 s by interglomerular synchrony of infra-slow bursting.

17 and the characterization of allele-specific bursting.

18 he cellular properties underlying endogenous bursting.

19 hey play a major role in neuronal firing and bursting.

20 hrough L-type channels during pacemaking and bursting.

21 s sufficient to produce alternating rhythmic bursting (0.15-1 Hz) in lumbar flexor motoneurons.

22 eading to asynchronous and imprecise rebound bursting; (2) TRN-mediated lateral inhibition that furth

23 In adult SH rats (n = 8), the VR response to bursting (44.6 +/- 3.9%) was not different to tonic (37.

24 Thus, rhythmic bursting, a fundamental mode of nervous system activity

25 ful tools for characterizing transcriptional bursting across genes under different environmental cond

26 Moreover, chronic restraint stress induces bursting action potentials in LHb neurons, which are abo

27 While GABAAR or NMDAR were not required for bursting, activation of AMPARs by climbing fibers (CFs)

28 olved in cellular responses such as neuronal bursting activity and cardiac rhythm.

29 Graphene electrodes record high-frequency bursting activity and slow synaptic potentials that are

30 potential depolarisation and high-frequency bursting activity at preferred whisker angles.

31 , which explains the pump's contributions to bursting activity based on Na(+) dynamics.

32 ution of the Na(+)/K(+) pump current to such bursting activity has not been well studied.

33 supported by the finding of an increased MN bursting activity in immature SOD1(G93A) spinal cords an

34 methods to show that synchronous infra-slow bursting activity in mitral cells of the mouse accessory

35 is a key determining factor for the onset of bursting activity in mouse ventricular myocytes.

36 stonic mice revealed abnormal high-frequency bursting activity in neurons of the deep cerebellar nucl

37 n increase in the frequency and amplitude of bursting activity in neurons with intrinsic bursting pro

38 ntributes to the development of epileptiform bursting activity in the TSC2(+/-) CA3 region of the hip

39 At 2 d postinjury, intrinsic bursting activity is lost within the intact population.

40 T cholinergic axons selectively enhanced the bursting activity of mesolimbic dopamine neurons that we

41 namics of different ionic currents shape the bursting activity of neurons and networks that control m

42 nteracts with the h-current can regulate the bursting activity of neurons and networks.

43 rter, to examine the role of the pump on the bursting activity of oscillator heart interneurons in le

44 he Po predominately by facilitating extended bursting activity of the channel but the underlying biop

45 aine injection increases the firing rate and bursting activity of VTA dopamine neurons, and that thes

46 e, amplitude, and duration; (2) intermediate bursting activity showed increased rate and duration, bu

47 odulated during c-tsDC stimulation: (1) fast bursting activity showed increased rate, amplitude, and

48 ation, but decreased amplitude; and (3) slow bursting activity showed increased rate, but decreased d

49 lateral caudal (IC) cells, generate inherent bursting activity that depends upon a persistent sodium

50 or interspike interval variability of phasic bursting activity was affected.

51 be assessed because when varied individually bursting activity was not maintained.

52 In addition, spinal bursting activity was significantly modulated during c-t

53 Characteristics of bursting activity were assessed during c-tsDC stimulatio

54 in creating avalanches--patterns of complex bursting activity with scale-free properties--is examine

55 osed of a few hundred neurons that alternate bursting activity with silent periods, but the mechanism

56 oot stimulation could evoke regular rhythmic bursting activity, and our data suggested that capsaicin

57 ance parameters maintaining functional leech bursting activity, we applied Principal Component Analys

58 nces in the robust maintenance of functional bursting activity, we used our existing database of half

59 ockers, which produced three rates of spinal bursting activity: fast, intermediate, and slow.

60 c dysfunction, evident as: an increase in LC bursting activity; in tyrosine hydroxylase expression an

61 in tissues to find that this transcriptional bursting also occurs in the mammalian liver and may cont

62 gthen, whereas in Dendronotus, curare halted bursting altogether.

63 sol generated from freshwater through bubble bursting, analogous to SSA from seawater.

64 n activity in parkin larvae revealed reduced bursting and a striking reduction in evoked and miniatur

65 Muscimol reduced and picrotoxin enhanced bursting and both drugs changed the temporal pattern of

66 TBPH mutants displayed reduced motor neuron bursting and coordination during crawling and restoring

67 n fails to elicit postsynaptic complex-spike bursting and does not induce LTP at ventral SC synapses.

68 The changes in bursting and excitability were related to the altered AD

69 nd factors provides one explanation for gene bursting and it also indicates that REs may often be uno

70 thophysiology, including enhanced prefrontal bursting and locomotor hyperactivity, which have been li

71 H neurons contained immunoreactive dopamine: bursting and nonbursting neurons.

72 Oxytocin excited both bursting and nonbursting neurons.

73 Dynorphin-A inhibited both bursting and nonbursting TH neurons by activating kappa

74 of patient-derived neurons show spontaneous bursting and other evidence of hyperexcitability.

75 In addition, these two subtypes, the bursting and regular firing type, are differentially int

76 were dramatically elevated, favoring rebound bursting and seizure generation.

77 sociation with ripples, and showed increased bursting and temporal coactivation during postexperience

78 s have well-characterized dual firing modes: bursting and tonic spiking.

79 loops are a likely cause of transcriptional bursting and, thus, biological noise.

80 iption dynamics in vivo (e.g. transcription 'bursting') and may also have practical implications for

81 c cortex), reduced IL single-unit firing and bursting, and attenuated IL gamma and theta oscillations

82 as rich behaviors such as quasiperiodicity, bursting, and long-memory effects tied to the size of th

83 ggest a structural basis for transcriptional bursting, and offer new insights into the mechanism of t

84 ivity, boosting synaptic inputs and enabling bursting, and somatic calcium cannels promoting regular

85 t CA1 network oscillations, pyramidal neuron bursting, and spatial information coding in vivo.

86 case, the system generates a transcriptional bursting, and the mean mRNA level peaks at a finite time

87 Moreover, such patterned bursting appears critical for motor plasticity.

88 Bursting approaches antiphase to cAMP waves, with accele

89 f this is that pacemaking and, even more so, bursting are associated with a larger Ca(2+) entry throu

90 taneous cross-unit synchrony and single-unit bursting are de facto physiological correlates of tinnit

91 chanisms involving pacemakers, inhibition or bursting are problematic and that simplifying assumption

92 hanisms involving pacemakers, inhibition, or bursting are problematic and that simplifying assumption

93 lling and adhesion, migration, and oxidative bursting, are better measured in seconds or minutes than

94 therefore feature alongside transcriptional bursting as a source of noise.

95 Synchrony and bursting, as well as spontaneous firing rate (SFR), corr

96 nd find that at virtually all loci, episodic bursting--as opposed to constitutive expression--is the

97 c firing was seen in depolarized regimes and bursting at hyperpolarized membrane potentials.

98 ple effects: (i) increasing excitability and bursting at moderate spike rates but reducing firing at

99 ved ligand RALF34, which induces pollen tube bursting at nanomolar concentrations.

100 is ejected into the atmosphere during bubble bursting at the organically enriched sea-air interface o

101 showed the expected loss of visually evoked bursting at the same age as wild-type, two days before e

102 swered: is the coordination due to parasites bursting at the same time or at a particular time?

103 an lead to new insights into transcriptional bursting based on measurements of steady-state mRNA/prot

104 y an algorithm for clustering cells by their bursting behavior (Simulated Annealing for Bursty Expres

105 work into easily achievable states, affected bursting behavior differently than neurons with high mod

106 re likely to be necessary for driving normal bursting behavior in HVC premotor neurons and suggest th

107 rved excitatory synapses contributed more to bursting behavior than inhibitory synapses.

108 ure AIIs, membrane hyperpolarization elicits bursting behavior.

109 ynapses onto itself, in driving network-wide bursting behavior.

110 ction potential and [Ca(2+)]i alternans, and bursting behaviors.

111 rom time varying distributions mimicking the bursting behaviour of observed saltatory growth.

112 In bursting bubble ionization (BBI), droplet ejection is ac

113 many cells would be damaged by a particular bursting bubble, or more precisely how much volume aroun

114 gational rate distribution associated with a bursting bubble, we introduce the concept of a fragmenta

115 re mainly formed by film drops produced from bursting bubble-cap films, which become enriched with hy

116 contrast, jet drops formed from the base of bursting bubbles are postulated to mainly produce larger

117 ssessing how effectively fluid motion within bursting bubbles at the ocean surface can shear microsco

118 own dust and sea salt from sea spray through bursting bubbles have been considered the chief mechanis

119 ered in the ocean are breaking waves and the bursting bubbles produced by such waves.

120 al feedback as the source of transcriptional bursting, but a reconciliation of this perspective with

121 expression were induced by action potential bursting, but not by glutamate bath application activati

122 rrent to the regulation of glucose-dependent bursting by reproducing experimentally observed changes

123 We find that locomotor-like rhythmic bursting can be induced unilaterally or independently in

124 CAF, a process comparable to transcriptional bursting causing temporary allelic imbalance.

125 cortico-cortical projections, and intrinsic bursting cells (IB), which have subcortical projections.

126 flected in an asymmetric wiring scheme where bursting cells and regular firing cells are recurrently

127 Bursting cells are selectively used to transmit informat

128 Specifically, bursting cells exhibit the least amount of drive, while

129 cells, and communication between regular and bursting cells is unidirectional.

130 ul separation of regular-spiking neurons (or bursting cells) from fast-spiking cells resulted in well

131 ect population spikes (PSs) from clusters of bursting cells, but HFOs in the ripple and the fast ripp

132 n subtypes exclusively exist from regular to bursting cells.

133 numerous onto regular firing cells than onto bursting cells.

134 Our results suggest that neurons with unique bursting characteristics are a fundamental component of

135 The gating characteristics (bursting, cooperativity) of the TRPV4 cluster enhance Ca

136 we found that duty cycles of transcriptional bursting depend on the intracellular gyrase concentratio

137 erneurons, including tonic firing or initial bursting discharge, Ih currents, and islet cell morpholo

138 g differentiation accentuate transcriptional bursting due to the crowding effect of chromatin.

139 isingly, each element has a distinct role in bursting during transcriptional activation by gamma-inte

140 based upon RNA hybridisation studies suggest bursting dynamics arise from alternating inactive and pe

141 cted communities, where neurons obey chaotic bursting dynamics.

142 ased the amplitude of drug-induced locomotor bursting, effects that were dependent on the presence of

143 on is governed by islet oscillations such as bursting electrical activity and periodic Ca2+ entry in

144 ism, intracellular Ca(2+) concentration, and bursting electrical activity.

145 ons in intracellular Ca(2+) that result from bursting electrical activity.

146 ls did not contain dopamine and did not show bursting electrical activity.

147 elds to explain their observed quiescent and bursting emission, implying that the field strength with

148 ique topology of the AOB network, infra-slow bursting enables integration and binding of multiple che

149 ering promoted the initiation of synchronous bursting events but entailed incomplete network recruitm

150 ngal spores at high humidity may explain the bursting events of new particle formation in Amazonia.

151 g cortex, is a major source of the transient bursting events that are critical for brain maturation.

152 dergoing a cyclical sequence of swelling and bursting events, coupled to the membrane's compositional

153 estigate the elongational rates generated in bursting films within aqueous bubble foams using both la

154 type calcium currents, and tonic- or initial bursting firing patterns, and received weak excitatory s

155 des and duration but generate very different bursting frequencies, with strong enhancers producing mo

156 sion, suggesting that enhancer regulation of bursting frequency is a key parameter of gene control in

157 ogenous DA release increases ETC spontaneous bursting frequency.

158 ray particles ejected as a result of bubbles bursting from artificial seawater containing salt and or

159 rollability significantly affects changes in bursting from autaptic connections.

160 y measurements of microbes ejected by bubble bursting, further supporting the assignment of BioSS mas

161 on, sustention, or termination of the phasic bursting generated in an intrinsic manner without synapt

162 Bursting has been demonstrated in a wide range of pro- a

163 Transcriptional bursting has been observed across species and is one of

164 Such bursting has important consequences for cell-fate decisi

165 Increased cross-unit synchrony and bursting have been linked to tinnitus in several higher

166 an NMDA receptor-driven network of intrinsic bursting (IB) neurons in layer 5, activating a source of

167 Intrinsic-bursting (IB) neurons, the L5 corticofugal neurons, exhi

168 stinguish regular spiking (RS) and intrinsic bursting (IB) subtypes.

169 king (RS), irregular-spiking (IR), initially bursting (IB), stuttering (Stu), single-spiking (SS), fa

170 causes abnormal vocal variability and excess bursting in a frontal cortical nucleus.

171 ontaneous emergence of synchronized periodic bursting in a network of cultured dissociated neurons fr

172 Here, we postulated that bursting in AIIs underlies the initiation of glutamaterg

173 The presence of increased synchrony and bursting in DCN fusiform cells suggests that a neural co

174 The curare-impaired bursting in Dendronotus was also restored by rewiring th

175 ar locomotor network could trigger locomotor bursting in distant thoracic segments through short and

176 how DNA topology results in transcriptional bursting in E. coli.

177 extent of extrinsic noise and transcription bursting in gene expression.

178 sed the amplitude and frequency of intrinsic bursting in inspiratory neurons.

179 double-knockout (DKO) mice lack epileptiform bursting in lateral septal neurons and exhibit reduced s

180 itative analysis, we examine transcriptional bursting in living Drosophila embryos.

181 the M-current, a conductance that modulates bursting in mature AIIs, blocked retinal wave generation

182 densities by 22% or more eliminates rebound bursting in model thalamic reticular nucleus (TRN) neuro

183 inputs frequently reaching the threshold for bursting in most pyramidal cells.

184 s a general model for synchronous infra-slow bursting in neuronal networks.SIGNIFICANCE STATEMENT Inf

185 rate distinct differences of post-inhibitory bursting in organic dystonia versus controls.

186 supports the hypothesis that delta frequency bursting in particular thalamic nuclei has a causal role

187 ossibly these changes contribute to periodic bursting in pyramidal cells, an essential component in t

188 ivity but are critical for the transition to bursting in response to CRH.

189 ivity but are critical for the transition to bursting in response to CRH.

190 d relationship between population coding and bursting in single granule cells by which spiking in a s

191 now test the hypothesis that post-inhibitory bursting in the human pallidal receiving nucleus of the

192 9], thought to be triggered by low-frequency bursting in the thalamus [10, 11].

193 ical projection neurons do not show enhanced bursting in these mutants, suggesting that this feature

194 (2015) have developed methods to study gene bursting in tissues to find that this transcriptional bu

195 annel-dependent functions, including rebound bursting in TRN neurons, with potential implications for

196 LTD, and significantly reduces epileptiform bursting in TSC2(+/-) hippocampal slices.

197 Increased bursting in vivo properties of these dopamine neurons an

198 y modulated bursting patterns, revealed that bursting increases vascular resistance (VR) more than to

199 romoter elements to modulate transcriptional bursting individually allows combinatorial fine-tuning o

200 Interestingly, epileptiform bursting induced by agonists for metabotropic glutamate

201 Recurrent bursting-induced increase in [Ca](i) levels was reduced

202 hese shells can relieve internal pressure by bursting intermittently, shrinking and re-growing, provi

203 hypofunction model show that delta frequency bursting is dependent on T-type Ca(2+) channels, a resul

204 chieved, we investigated how transcriptional bursting is entrained by a naturally oscillating signal,

205 al core promoter elements to transcriptional bursting is not known.

206 This low-frequency bursting is resistant to block of glutamatergic and GABA

207 e day and at night and that the frequency of bursting is what is modulated in a circadian fashion.

208 wo major types of CeA neurons, low-threshold bursting (LTB) neurons and regular spiking (RS) neurons,

209 Interestingly, the frequency of network bursting matches the average of the intrinsic frequencie

210 Here we investigate bursting mechanism in live cells by quantitative imaging

211 t input current and eta, such as square wave bursting, mixed mode oscillations, and pseudo-plateau po

212 when Ca(2)(+) channel activity switched to a bursting modality.

213 We demonstrate that lLNv bursting mode relies on a cholinergic input because appl

214 rom bacteria-to-bacteria are well-fit with a bursting model of gene transcription.

215 te the kinetic parameters of gene expression bursting, namely the rate that genes turn on, the rate t

216 st to rat, the regular oscillations of mouse bursting neurons depend on a mechanism involving both T-

217 K(ir)2.2, and K(ir)2.3 within spontaneously bursting neurons.

218 nguish between regimes where transcriptional bursting occurs from regimes reflecting constitutive tra

219 ce surprisingly large flow rates: during the bursting of a bubble having an air volume of 10 mm(3), e

220 Alkali injury from bursting of chuna packets was the most common mode of in

221 Flooding resulting from the bursting of dams formed by landquake events such as rock

222 Here, we demonstrate increased synchrony and bursting of fusiform cell spontaneous firing, which corr

223 r, these findings prove that transcriptional bursting of highly expressed genes in bacteria is primar

224 mber of abortive infection events, including bursting of ITs and a reduction in the number of nodules

225 Finally, we found that bursting of lLNvs depends on an input from visual circui

226 In particular, transcriptional bursting of mRNAs from the promoter has been implicated

227 For example, transcriptional bursting of mRNAs has been shown to be a major source of

228 Nanoscopic aerosols arising from bubble bursting of natural and artificial seawater have been id

229 T-type Ca(2+) channels in the high-frequency bursting of Re neurons.

230 e contribution of PVN to support of rhythmic bursting of SNA during dehydration and to elucidate whic

231 have been suggested to result from excessive bursting of thalamocortical cells.

232 PG) was necessary and sufficient for osmotic bursting of the cell.

233 ere we analyze the relative contributions to bursting of the individual core promoter elements-CCAAT,

234 We observed transcriptional bursting of the lux receptor in cells stimulated by near

235 e receptive synergid cell and the coincident bursting of the pollen tube inside the ovule to release

236 n use populations of rhythmically active or 'bursting' olfactory receptor neurons (bORNs) to extract

237 otor synchrony characterized by simultaneous bursting on both sides at twice the swimming frequency.

238 een explained, the source of transcriptional bursting (one of the most well-known sources of stochast

239 rts that interact to produce stable rhythmic bursting; one part is the primary half-center kernel, an

240 possibly through effects on transcriptional bursting or elongation rate.

241 ain immunoreactive dopamine, and show either bursting or nonbursting electrical activity.

242 d that lLNvs fire action potentials (APs) in bursting or tonic modes and that the proportion of neuro

243 copy, whereby stable as well as transiently bursting oscillations ensue in single cells.

244 crab Cancer borealis, the duty cycle of the bursting pacemaker kernel is highly robust between 7 and

245 ins have heretofore focused on intrinsically bursting "pacemaker" cells operating in conjunction with

246 We study the response of a bursting pallidal neuron to different patterns of synapt

247 ects genes exhibiting allelic differences in bursting parameters and genes whose alleles burst non-in

248 st size, but how regulatory elements control bursting parameters remains unclear.

249 Results revealed strong transcriptional bursting, particularly for the glycolytic promoter.

250 to contribute differentially to the overall bursting pattern of the promoter during basal transcript

251 periods of rapid transitions, reminiscent of bursting patterns first recorded in single ion channels

252 hancers to perturbation, the transcriptional bursting patterns of enhancers, and the ability of an en

253 tem cardio-respiratory regions that generate bursting patterns of SNA, we sought to determine the con

254 thetic chain (L3) with respiratory modulated bursting patterns, revealed that bursting increases vasc

255 membrane conductances necessary to generate bursting, pharmacological activation of the M-current, a

256 During the late bursting phase, the duration, number, and rate of occurr

257 rmittent forcing that precedes switching and bursting phenomena.

258 ot its wild-type form, partially rescues the bursting phenotypes of anx1 anx2 PTs and fer root hairs

259 at linked reporter genes exhibit coordinated bursting profiles when regulated by a shared enhancer, c

260 bursting activity in neurons with intrinsic bursting properties after exposure to PGE2.

261 s provide the first description of pacemaker bursting properties in embryonic preBotC neurons and ind

262 study did not exhibit intrinsic oscillatory bursting properties, but were electrophysiologically dis

263 l profiles provides robust control of axonal bursting properties.

264 tial subset exhibiting intrinsic oscillatory bursting properties.

265 ested the hypothesis that there is a general bursting property in both the timing and sequential patt

266 daily rhythms in firing event frequency and bursting proportion under light:dark conditions.

267 gnificantly increased spontaneous firing and bursting rates of VTA DA neurons, higher doses strongly

268 However, the mechanistic origins of bursting remain elusive.

269 ever, the molecular basis of transcriptional bursting remains poorly understood.

270 ask, motivational salience was encoded by BF bursting response that occurred before RT.

271 tative noncholinergic BF neurons with phasic bursting responses to the go signal were nearly complete

272 Brief (1 hr) periods of postsynaptic bursting selectively depressed AMPA receptor (R) synapti

273 ed patterns of neuronal activity and altered bursting showed a significant positive correlation with

274 ized cancer cells quickly through budding or bursting similar to simple organisms like fungi.

275 During bursting, solute leakage through transient pores relaxes

276 the lifetime of the SD's high-accessibility (bursting) state and prolongs the time between bursts.

277 nset of the VR response was also quicker for bursting stimulation (rise time constant = 1.98 +/- 0.09

278 prevalent during periods of inactivity while bursting strongly correlates with locomotor output.

279 We show that a bursting subset of primary olfactory receptor neurons (b

280 enabled membrane potential oscillations and bursting, suggesting that all three pathological changes

281 as the "hit-and-run" model and transcription bursting that could not be obtained by in vitro biochemi

282 ages, IC cells switch to a sustained mode of bursting that permits generation of high-frequency oscil

283 and intracellular recordings showed periodic bursting that progressively decreased in frequency.

284 ations and is largely due to transcriptional bursting, the episodic production of mRNAs in short, int

285 dynamic clamp restored the original rhythmic bursting, thereby affirming the roles of those synapses.

286 sured simultaneously with membrane potential bursting to determine the phase relationships between th

287 shifting thalamo-cortical transmission from bursting to single spiking.

288 Bursting transcription can cause individual cells to rem

289 ese processes give rise to stochastic, often bursting, transcriptional activity.

290 t repressed in distal dendrites and display "bursting" translation.

291 gardless of their membership within distinct bursting versus nonbursting basal forebrain subpopulatio

292 The number of autapses required to induce bursting was lowered by adding autapses to high degree e

293 Unlike rats, the mechanism underlying bursting was not dependent on gap junctions but required

294 l extensor activity, whereas rhythmic flexor bursting was not perturbed during extensor deletions.

295 -range chromatin contacts on transcriptional bursting, we forced an LCR-beta-globin promoter chromati

296 nce of tinnitus, and increased synchrony and bursting were associated with SFR elevation.

297 increases in trial-by-trial variability and bursting when birds sing alone rather than to females.

298 SCALE to analyze genome-wide allele-specific bursting, with adjustment of technical variability.

299 ochastic gene expression and transcriptional bursting, with implications for regulation of pluripoten

300 xor motor neuron pools can be recruited into bursting without any activity in other nearby flexor mot