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5 regulate EGFR-dependent Delta transcription by antagonizing a repressor function of Suppressor of Ha
6 that puc modulates gene expression responses by antagonizing a Rho GTPase signal transduction pathway
7 GN membrane proteins between the TGN and PVC by antagonizing a TGN retention signal (TLS2) and facili
8 1p exerts its effect on the RAS/cAMP pathway by antagonizing a ubiquitin-mediated process, excess ubi
9 that stablizes several nutrient transporters by antagonizing a ubiquitin-mediated protein degradation
10 ng histone deacetylase 3 to DNA-bound GR and by antagonizing acetylation of histone H3 and H4 induced
12 ate, not by repressing AG transcription, but by antagonizing AG activity in the center of the flower.
13 by moving alphavbeta3 to the cell front, but by antagonizing alpha5beta1 recycling, which, in turn, i
14 ctor 2, indicating that K1L and C7L function by antagonizing an IFN effector(s) but with a mechanism
19 binding with Msp2 monoclonal antibodies and by antagonizing binding and propagation with recombinant
20 corticoid action in target tissues, possibly by antagonizing biological actions of diurnally fluctuat
21 represses differentiation inhibitory signals by antagonizing BMP receptor-activated Smad activity whi
22 h may promote the generation of interneurons by antagonizing BMP, but may not be required directly fo
25 tially, by altering protein degradation, and by antagonizing BR-induced changes in microtubule organi
26 eriments, we show here that SerRS intervenes by antagonizing c-Myc, the major transcription factor pr
29 2A) antagonist in vivo is greatly attenuated by antagonizing cannabinoid CB(1) receptor signaling or
30 y and, in A431 cells, reduced VDR expression by antagonizing CCAAT enhancer binding protein-beta tran
32 hatase Clp1p/Flp1p regulates G2/M transition by antagonizing CDK activity and is essential for coordi
33 turn, may promote the activation of the SIN by antagonizing Cdk activity until cytokinesis is comple
34 transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repre
35 that facilitates transcriptional enhancement by antagonizing chromatin-mediated transcriptional repre
37 t phosphorylation of His358 activates KCa3.1 by antagonizing copper-mediated inhibition of the channe
40 tudies indicate that kinesin-5 works in part by antagonizing cytoplasmic dynein and that these motor-
41 reby inhibit the decay of labile transcripts by antagonizing destabilizing proteins that target these
42 sequence-specific replication termini (Ter) by antagonizing DNA unwinding by the replicative helicas
43 viate the positive symptoms of schizophrenia by antagonizing dopamine D2 receptors expressed by stria
44 The overexpressed WntD inhibits invagination by antagonizing Dorsal nuclear localization, as well as
45 ntally induced in healthy human eSCs in situ by antagonizing E-cadherin, combined with transforming g
47 53-dependent cell cycle arrest in G1 and G2, by antagonizing early or late p53-mediated responses, re
48 xperiments demonstrate that BS69 promotes IR by antagonizing EFTUD2 through physical interactions.
49 ella-infected epithelia may promote Cl- flux by antagonizing EGF inhibition mediated through PtdIns3K
54 l for the induction of LTD, possibly in part by antagonizing ERK signaling in hippocampal neurons.
55 BM attenuates tumor cell migratory potential by antagonizing ERK/AKT phosphorylation induced by the c
58 positive multiple myeloma xenografts in mice by antagonizing FGFR3 signaling and eliciting antibody-d
62 SC subpopulations in a heterogeneous mixture by antagonizing formation of the chromatin modifier PRC2
63 f the IL-7 receptor alpha-chain (IL-7Ralpha) by antagonizing Foxo1 and negatively regulated signaling
65 and has been proposed to promote wakefulness by antagonizing function of the adenosine A2A receptor.
67 responses to skin cooling and were reversed by antagonizing GABA(A) receptors in the medial preoptic
69 repression in effector CD8 T cells and acted by antagonizing GABPalpha binding and recruiting histone
70 oocyte growth and meiotic maturation in part by antagonizing gap-junctional communication between she
73 LPA) regulates hepatocyte glucose production by antagonizing glucagon-induced expression of the gluco
74 ) hampers neutrophil expansion and migration by antagonizing granulocyte colony-stimulating factor (G
75 A-P plays a central role in cydAB regulation by antagonizing H-NS repression of cydAB transcription w
76 g in fibroblasts suppresses tumor metastasis by antagonizing HGF/c-Met signaling within tumor epithel
79 dicate that H4K20me3 invokes gene repression by antagonizing hMOF-mediated H4K16Ac and suggest that o
80 del whereby JMJD2A regulates DNA replication by antagonizing HP1gamma and controlling chromatin acces
81 ns as a switch for beta1 integrin activation by antagonizing ICAP1 (Integrin Cytoplasmic Associated P
82 ns as a switch for beta1 integrin activation by antagonizing ICAP1-mediated inhibition of integrin ac
83 opic budding from the WD or the ureter stalk by antagonizing inductive signals from the metanephric m
84 at TRE might exert beneficial effects in PPH by antagonizing inflammatory cytokine production in the
85 , critical regulators of cell death function by antagonizing Inhibitor of Apoptosis Proteins (IAPs),
86 te meiotic maturation, which it does in part by antagonizing inhibitory sheath/oocyte gap-junctional
87 ligase activities of TRAF6, TRAF2, and cIAP1 by antagonizing interactions with the E2 ubiquitin conju
88 le E3L is known to support viral replication by antagonizing interferon (IFN) effectors, including PK
90 (hyaA) expression under anaerobic conditions by antagonizing IscR binding at P(hyaA), since IscR repr
91 that SWI/SNF controls transcriptional memory by antagonizing ISWI-like chromatin remodeling enzymes.
92 2A-B55beta promotes cyclin E1 overexpression by antagonizing its degradation and its inhibition could
95 ARF tumor suppressor protein stabilizes p53 by antagonizing its negative regulator, Mdm2 (Hdm2 in hu
96 mulation of the labile monomeric GTPase RhoB by antagonizing its normal proteolytic destruction, pres
98 rgin, which raises intracellular Ca2+ levels by antagonizing its sequestration, induced immunophenoty
99 the chick) allows sensory organ segregation by antagonizing lateral induction and promoting commitme
100 tumor suppressor that controls proliferation by antagonizing LEF1/beta-catenin-mediated transcription
101 vide a novel avenue to bone anabolic therapy by antagonizing LRP4 sclerostin facilitator function.
104 vel regulator of MT stability that functions by antagonizing mDia1 activity toward actin filaments an
108 P inhibits zinc-dependent induction of Dnmt1 by antagonizing metal-responsive transcription factor-1
110 nstatement by mGluR2/3 blockade was reversed by antagonizing mGluR5, but reinstated sucrose seeking i
113 /N can cause either an apparent hyperalgesia by antagonizing mu opioid-induced analgesia or a net ana
115 ine-rich proteoglycan, inhibits tumor growth by antagonizing multiple receptor tyrosine kinases inclu
116 ssing the c-myc gene P2 promoter, as well as by antagonizing Myc-dependent transactivation through E-
117 activity maintains the prometaphase spindle by antagonizing Ncd and another unknown force-generator
118 IL-4 obliterates osteoclast differentiation by antagonizing NF-kappaB activation in a STAT6-dependen
121 IPergic electrical field-induced relaxation (by antagonizing nitric oxide synthesis or receptor inter
123 tivating Prospero to limit proliferation and by antagonizing Notch signaling to prevent dedifferentia
125 gulates Flo11-dependent developmental events by antagonizing Nrg-mediated repression of the FLO11 gen
126 indicates that Snf1-Gal83 affects adherence by antagonizing Nrg1- and Nrg2-mediated repression of th
127 The ability to control premature delivery by antagonizing or silencing the ECE-1/ET-1 system offer
128 To determine if Chx10 regulates cell number by antagonizing p27(Kip1) activity, we generated Chx10,
129 egulator of the p53 tumor suppressor protein by antagonizing p53 transactivation activity and targeti
130 Wip1) promotes recovery in G2-arrested cells by antagonizing p53, it is dispensable for recovery from
132 stage targeted in ABC-DLBCL transformation--by antagonizing pathways distinctive of GCB-DLBCL, inclu
134 ll growth, proliferation, and cell migration by antagonizing phosphatidylinositol 3-kinase (PI3K).
137 cts as a tumor suppressor, at least in part, by antagonizing phosphoinositide 3-kinase (PI3K)/Akt sig
143 y DR3 signaling, suggesting that this occurs by antagonizing pro-apoptotic signals induced by TNF.
144 nterventional approach to inhibit cell death by antagonizing proapoptotic Bcl-2 family members that r
145 ammatory reactions and prevents autoimmunity by antagonizing proinflammatory transcriptional activiti
146 est that PTEN may suppress tumor cell growth by antagonizing protein tyrosine kinases and may regulat
147 gonists from neurons in nociceptive networks by antagonizing putative presynaptic inhibitory opioid a
148 gastrulation, Hh switches to a negative role by antagonizing RA-mediated specification of the endocri
150 2-79, modulate KSR-dependent MAPK signalling by antagonizing RAF heterodimerization as well as the co
151 e and lifetime of SUMO-conjugated substrates by antagonizing reactions catalyzed by SUMO-conjugating
152 rs specifically within Ras-mutant cell lines by antagonizing release of negative feedback signalling,
153 s(36) is to promote transcription elongation by antagonizing repressive Lys(36) methylation by Set2.
154 target gene, p21 (also known as Cdkn1a), or by antagonizing reprogramming-induced apoptosis in mouse
158 s to reach and cross the spinal cord midline by antagonizing Robo1/2-mediated repulsion from midline-
160 th in physiological conditions and in stress by antagonizing SA-dependent growth inhibition through U
161 URX neurons seems to suppress social feeding by antagonizing signalling through a cyclic GMP-gated io
162 e hair colour and body weight, respectively, by antagonizing signalling through melanocortin receptor
165 sults suggest that MIM promotes ciliogenesis by antagonizing Src-dependent phosphorylation of Cortact
166 ed SOCS proteins enhance SREBP-1c expression by antagonizing STAT3-mediated inhibition of SREBP-1c pr
170 ty functions to maintain euchromatic regions by antagonizing Su(var)3-9-mediated heterochromatization
171 berus/Dan gene family, which induces targets by antagonizing symmetrically expressed BMP signals.
175 specification in the second heart precursors by antagonizing Tbx1/10-mediated inhibition of GATAa and
176 performance in adult females was unaffected by antagonizing testosterone in utero, i.e., stress stil
178 hat 9-cis-RA possesses anti-fibrotic ability by antagonizing TGF-beta1 in mesangial cells and that 9-
180 e apoptotic effect of BAD in primary neurons by antagonizing the ability of growth factors to inhibit
183 re involved in regulating cellular responses by antagonizing the action of protein tyrosine kinases.
184 r role in the elimination of class I-IV NFRs by antagonizing the action of RSC, a remodeling complex
185 arrests replication forks in a polar fashion by antagonizing the action of the replicative helicase (
188 n may play a negative role in cell migration by antagonizing the actions of Rac on cytoskeletal organ
189 could be involved in follicular development by antagonizing the actions of theca cell-derived BMPs.
190 ens the activation of inflammatory responses by antagonizing the activation of the NF-kappaB canonica
191 PPAR-gamma inhibits gene expression in part by antagonizing the activities of the transcription fact
193 actor gene expression independently of Notch by antagonizing the activity of hypoxia-inducible factor
196 with this, Sufu regulates Gli protein levels by antagonizing the activity of Spop, a conserved Gli-de
198 ecifies and patterns the hindbrain territory by antagonizing the activity of the spinal cord specific
199 uggest that 5-HT inhibits fighting, in part, by antagonizing the aggression-promoting action of the A
200 of lipid disorders, such as atherosclerosis, by antagonizing the agonistic action of endogenous LXR l
202 tated NK cell proliferation during infection by antagonizing the anti-proliferative factor Blimp-1 (P
203 protein CED-9 prevents programmed cell death by antagonizing the Apaf-1-like cell-death activator CED
206 plakoglobin regulates nuclear transcription by antagonizing the binding of beta-catenin to TCF/LEF p
208 gulate microtubule plus-end assembly in part by antagonizing the catastrophe-promoting function of ki
209 ant, prevent the 2-AG-induced cell migration by antagonizing the CB2 and abnormal-cannabidiol-sensiti
210 abilizes acetylated cohesin complexes on DNA by antagonizing the cohesin release factor Wings-apart l
211 S. cristatus, may be beneficial to the host by antagonizing the colonization and accumulation of per
212 f HIF1alpha/VEGF-mediated tumor angiogenesis by antagonizing the crosstalk between PTMs involving HIF
213 he Bcl-2 homologue CED-9 prevents cell death by antagonizing the death-promoting activities of CED-3,
214 s, this restriction was partially surmounted by antagonizing the DNA-dependent protein kinase (DNA-PK
215 ry of hemogenic vascular niche specification by antagonizing the dorsal-ventral regulatory limits of
216 ting p40 could inhibit the generation of CTL by antagonizing the early IL-12 "differentiation" signal
217 nregulates the Na(+)-Cl(-) cotransporter NCC by antagonizing the effect of full-length WNK1 when expr
218 ry effect over the T-helper 2 (Th2) response by antagonizing the effect of IL-4 on CD4(+) T cells and
219 fically enhances slow wave sleep, apparently by antagonizing the effects of acetylcholine on cortical
220 fically enhances slow-wave sleep, presumably by antagonizing the effects of acetylcholine on cortical
221 od vessel formation in the developing embryo by antagonizing the effects of Ang1 and Tie2 and was thu
222 otes the expression of floral homeotic genes by antagonizing the effects of DELLA proteins, thereby a
223 e that RACK1 is a repressor of E1A, possibly by antagonizing the effects of E1A on host gene transcri
224 oxidants may attenuate vascular inflammation by antagonizing the effects of intracellular reactive ox
226 ould function in a dominant-negative fashion by antagonizing the endogenous activity of GSK3beta and
227 ceptors [RXRs]) inhibit IL-6 promoter action by antagonizing the enhancer action of NF-IL6, a basic d
228 in repressing the formation of the organizer by antagonizing the expression of genes involved in orga
230 tes the equilibrium of splice site selection by antagonizing the facilitatory activity of MBNL1 and M
232 inducing apoptosis in whole cells, possibly by antagonizing the function of Bcl-2-related death supp
236 ly blocked the differentiation of TH17 cells by antagonizing the function of transcription factor ROR
239 EGL-4 and KIN-29 regulate CR gene expression by antagonizing the gene repression functions of the cla
240 g food restriction causes growth attenuation by antagonizing the GH stimulatory effects on chondrogen
241 onstrated that SUFU stabilizes Glis3 in part by antagonizing the Glis3 association with a Cullin 3-ba
242 uggesting that HilA promotes SPI4 expression by antagonizing the global transcriptional silencer H-NS
243 sed reversion to a less aggressive phenotype by antagonizing the growth effect of 17beta-estradiol.
244 Recently, anti-inflammatory effects in AD by antagonizing the histamine (H)-4 receptor have also b
247 that increases chloride secretion indirectly by antagonizing the inhibition of chloride secretion by
248 gh level of INS-7 from URX disrupts learning by antagonizing the insulin receptor-like homolog DAF-2
249 n which the modulation of TRPV1 is inhibited by antagonizing the interaction between TRPV1 and A kina
250 h the inhibition of TF transfer to platelets by antagonizing the interaction CD15 with P-selectin and
251 eant local anesthetics inhibit GIRK channels by antagonizing the interaction of PIP(2) with the chann
252 cocorticoids stimulate C3 subunit expression by antagonizing the interaction of this NF-kappaB protei
253 nC controls the scaffolding function of FtsZ by antagonizing the mechanical integrity of FtsZ structu
254 ding a skin peptide that modifies coat color by antagonizing the melanocyte-stimulating hormone recep
255 s tumor suppressive function in the pancreas by antagonizing the metaplastic conversion of acinar cel
259 osome 10 (PTEN) is a lipid phosphatase that, by antagonizing the phosphoinositol 3-kinase (PI3K) path
260 avoidance responses in Arabidopsis thaliana by antagonizing the phytohormones auxin and gibberellin.
261 PTEN helps regulate cellular chemotaxis by antagonizing the PI3K signaling pathway through depho
262 hat Sema-PlxnD1 signaling exerts this effect by antagonizing the proangiogenic activity of vascular e
267 fork protection complex is essential for PFA by antagonizing the Rrm3 helicase that displaces nonhist
268 supports VACV replication in mammalian cells by antagonizing the same antiviral factor(s) that is ind
269 F secretion, and thereby cell specification, by antagonizing the Senseless transcription factor in th
271 uggest that T(H)1 cells may mitigate uveitis by antagonizing the T(H)17 phenotype through the IFN-gam
274 ritical switch that prevents their apoptosis by antagonizing the trans-activation of puma by p53.
275 2 may inhibit E1A induced cell proliferation by antagonizing the transcriptional activation function
276 promotes the expression of vulval cell fates by antagonizing the transcriptional and chromatin-remode
277 alignant properties of human carcinoma cells by antagonizing the tumor-promoting activity of TGF-beta
278 evelopment of lethal cancer at least in part by antagonizing the tumor-suppressive functions of the S
279 rferes with the base-excision repair pathway by antagonizing the uracil DNA glycosylase (Ung2) enzyme
281 ity of targeting the stability of tankyrases by antagonizing their interaction with USP25 to modulate
286 ilitate expression of these cell cycle genes by antagonizing transcriptional repression mediated by p
287 lex overactivity can be partially normalized by antagonizing TRPv1 receptors in skeletal muscle.
288 sensing dependent upon cGAS-STING.IMPORTANCE By antagonizing type I interferon production and action,
290 cantly reduced LMP, suggesting that DHA acts by antagonizing upstream signals leading to lysosomal dy
291 ogenic behavior of endothelial cells largely by antagonizing vascular endothelial growth factor recep
292 placenta causes pre-eclampsia-like features by antagonizing vascular endothelial growth factor signa
293 a prominent role in the VEGF receptor system by antagonizing VEGF receptor signaling by acting as a d
294 production of runx1+ HSPCs in the AGM region by antagonizing VEGF signaling and subsequent assignment
298 that Scc1 sumoylation by Mms21 promotes SCR by antagonizing Wapl at a step after cohesin loading at
299 EGFR signaling directs cells to become notum by antagonizing wing development and by activating notum
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