ライフサイエンスコーパス: by exchanging

1 stigated the N1 TMD-head domain relationship by exchanging a prototypical "old" TMD (1933) with a "re

2 ntical amino acids, were essentially swapped by exchanging a single residue located at position 179 t

3 n of the electronegative potential of B-NRP2 by exchanging acidic residues for uncharged alanine (B-N

4 of Escherichia coli converse bidirectionally by exchanging acyl-homoserine lactone signals.

5 Profilins promote actin polymerization by exchanging ADP for ATP on monomeric actin and deliver

6 etween the GII.4-1987 and GII.4-2006 strains by exchanging amino acids in putative epitopes and chara

7 mino acid substitutions were only accessible by exchanging at least two nucleotides per codon, includ

8 their ability to form domain-swapped dimers by exchanging beta-strands.

9 orm their function or interact with partners by exchanging between conformational substates on a wide

10 By exchanging bone marrow-derived cells between CD36-exp

11 he library members interconvert continuously by exchanging building blocks with each other.

12 lusters (Pt, Ru, Rh) within MFI was achieved by exchanging cationic metal precursors into a parent ze

13 a particular Fab can be drastically altered by exchanging CDR.

14 bserved with ligand-receptor pairs generated by exchanging charged residues across ligand-receptor in

15 nsing, bacteria communicate with one another by exchanging chemical signals called autoinducers.

16 es, we generated recombinant ChAdOx1 vectors by exchanging components of the viral capsid reported to

17 strains and species will commonly cooperate by exchanging compounds.

18 stinct bromovirus RNA3 chimeras, constructed by exchanging CPs having the Delta919 deletion, demonstr

19 factor of 4 enhancement in activity achieved by exchanging Cs for Na was attributed to a higher cover

20 By exchanging cydB for cydB-gfpgcn4 on the E. coli chrom

21 Immune cells communicate by exchanging cytokines to achieve a context-appropriate

22 T) mediates ACh storage in synaptic vesicles by exchanging cytoplasmic ACh with vesicular protons.

23 cteria regulate gene expression collectively by exchanging diffusible signal molecules known as autoi

24 By exchanging discrete fragments of bvgAS, we found that

25 he host range attenuation phenotype of BPIV3 by exchanging each open reading frame (ORF) of a recombi

26 Pseudoviruses were created by exchanging each variable and constant domain of JR-CS

27 ofibrils, from which cTnI.cTnC was extracted by exchanging endogenous cardiac troponin with exogenous

28 directly involved in endosomal acidification by exchanging endosomal Cl(-) for H(+).

29 a steady state of biochemical reaction rates by exchanging energy and matter with the environment.

30 Three chimeric receptors were constructed by exchanging exon sequences between human NK1 and NK3 r

31 the alpha(v)beta(3) integrin antibody LM609 by exchanging extracellular K+ with Cs+ or by the applic

32 sv1-mediated LSHR, chimeras were constructed by exchanging fragments between the molecularly cloned S

33 Rho family of GTPases that induce activation by exchanging GDP for GTP have been identified.

34 e individually and in different combinations by exchanging genes between velogenic (highly virulent)

35 heterotrimeric G-proteins (Galphabetagamma) by exchanging GTP for the bound GDP on the Galpha subuni

36 all known materials, can be reversibly tuned by exchanging guests adsorbed from hydrostatic fluids.

37 By exchanging highly purified factors between reconstitu

38 eterogeneous community, only able to survive by exchanging histidine, leucine, uracil, and methionine

39 creates these flexible chromatin structures by exchanging histone H2A.Z onto nucleosomes and promoti

40 constructed 14 bovine/human IFNAR-1 chimeras by exchanging homologous subdomains in the extracellular

41 of (2)H labeling (e.g., <0.025% excess (2)H) by exchanging hydrogen (deuterium) in water with acetone

42 tion information, we have generated chimeras by exchanging individual domains of the Tac antigen with

43 is a multicellular event that is coordinated by exchanging intercellular signals.

44 beta-actin folding by PDCL3 can be relieved by exchanging its acidic C-terminal extension for that o

45 e properties of hemoglobin-S can be reversed by exchanging its normal alpha-globin subunits for zeta-

46 ld-shock induction of cspA was also achieved by exchanging its promoter with the non-cold-shock Ipp p

47 ral determinants that allow such variability by exchanging key amino acids located within the C-termi

48 This can be done by exchanging kidneys between two living-donor-recipient

49 -recipient pairs (living paired exchange) or by exchanging kidneys through a living-donor-cadaver-don

50 formed from an electron donor to an acceptor by exchanging ligands while the neutral form of the clus

51 s readily adapts by modulating Cu uptake and by exchanging metal cofactors for antioxidant SODs.

52 t has evolved rapidly since its introduction by exchanging mobile genetic elements, including integra

53 improved resolution is based on lowering m/z by exchanging multiple [-SC(11)H(22)N(CH(2)CH(3))(3)(+)]

54 By exchanging N- and C-terminal domains of MRF4 and MyoD

55 The protein forms an intertwined homodimer by exchanging N-terminal segments between chains.

56 d (skinned) cardiac muscle force development by exchanging native cardiac troponin (cTn) with differe

57 t pathogens and maintains energy homeostasis by exchanging neuronal and endocrine signals with other

58 ere the kinetic trapping problem is overcome by exchanging noninteracting replicas simulated at diffe

59 ion, two chimeric CV-B3 strains were created by exchanging nucleotides 104-184 and repeating the 5'UT

60 ein of Streptococcus pyogenes, were designed by exchanging one amino acid at a time, without altering

61 e swapped completely between these orthologs by exchanging only two residues.

62 By exchanging or directing co-occupancy of protein compl

63 ental virus' functional polymerase complexes by exchanging PB1 or PB2 genes decreased viral replicati

64 alyses of these viruses, and hybrids created by exchanging portions of the capsid gene, identified co

65 a set of viruses derived from these chimeras by exchanging portions of the capsid-coding regions, we

66 homolog-scanning experiments were conducted by exchanging progressively larger portions of the NH2-

67 By exchanging PSII samples with buffered (18)O water, we

68 properties of smooth muscle were determined by exchanging recombinant for endogenous LC17 in permeab

69 ilon and PKC-epsilon delta) were constructed by exchanging regulatory and kinase domains using polyme

70 By exchanging residues between the active Gbeta(2) subun

71 ied three residues critical for CD47 binding by exchanging residues on SIRPalpha with corresponding r

72 synthase 2 (Pss2) produce phosphatidylserine by exchanging serine for the head groups of other phosph

73 cts, the entire S-RNase sequence was sampled by exchanging single variable domains as well as larger

74 ion proteins mediate signaling communication by exchanging small molecules and dramatically stimulati

75 e incorporated into the LCD of muscle fibers by exchanging spin-labeled regulatory light chain for en

76 This is accomplished by exchanging strong binding bile salt surfactant coatin

77 f the CXC chemokine family, readily interact by exchanging subunits and forming heterodimers via exte

78 himeric pig-human and human-pig alpha-chains by exchanging the alpha(1-30) segments of human and pig

79 cted mutagenesis, this hypothesis was tested by exchanging the amino acids at position 5.46 between C

80 , initial anterior chamber concentration) or by exchanging the anterior chamber with 2 ml 10, 100, or

81 a)8 barrel in which a stable dimer is formed by exchanging the C-terminal helix.

82 attern of beta-arrestin binding was reversed by exchanging the C-terminal tails of the beta2 and V2 r

83 By exchanging the carboxyl tail domains of MOR and DOR a

84 piece of cross-linked polyacrylate hydrogel by exchanging the divalent counter-ions in the superfici

85 switched between blue and red in situ simply by exchanging the dye in the medium.

86 ) shift of Kv1.2 can be transferred to Kv2.1 by exchanging the extracellular linker between S3 and S4

87 , a series of chimeric receptors was created by exchanging the extracellular loops (ECL) of human NHE

88 s-of-affinity GRPR chimeric receptors formed by exchanging the four extracellular (EC) domains of GRP

89 we constructed chimeric recombinant viruses by exchanging the G and M genes of the attenuated SN str

90 By exchanging the germinal vesicle between mouse and pig

91 l utility of this approach were demonstrated by exchanging the GRP1 PH domain for that of TAPP1 (whic

92 change the specificity of the fiber protein by exchanging the head domain with another serotype whic

93 By exchanging the hypervariable domains of EspA(EPEC) an

94 and sufficient for PKA modulation, as shown by exchanging the I-II linker regions of the two channel

95 the rat and human receptor could be reversed by exchanging the intracellular C-terminal domain of the

96 devised a chimeric receptor signaling assay by exchanging the kinase domain of ALK-1 with either the

97 s reverse polarity during larval development by exchanging the locations of pre- and postsynaptic com

98 roperties of other Au(38) nanoparticles made by exchanging the monolayer ligands with different thiol

99 ycle, chimeric RTA proteins were constructed by exchanging the N-terminal and C-terminal domains of t

100 By exchanging the open reading frames of sodCI and sodCI

101 rine derivatives was significantly increased by exchanging the piperidine moiety with either N,N-dipr

102 By exchanging the polybasic regions between different PH

103 We demonstrate that by exchanging the pore domains JYL-1421, which is modali

104 ndelta and PKC-deltaepsilon were constructed by exchanging the regulatory and catalytic domains of PK

105 Calpha/delta and PKCdelta/alpha) constructed by exchanging the regulatory and catalytic domains of th

106 Chimeric alpha subunits were constructed by exchanging the S5-S6 interhelical loops of each domai

107 By exchanging the sp(3) C-H bonds in graphane with sp(3)

108 we created multiple chimeras of both lipases by exchanging the surface loops singly or in combination

109 rice yield under a range of field conditions by exchanging the top 15 cm of soil between 13 high-As a

110 By exchanging the V1/V2 domains between Envs of the same

111 odified an SV40-based shuttle vector, pZ189, by exchanging the wt T-antigen for a mutant SV40 T-antig

112 By exchanging these residues between guanylyl cyclase an

113 By exchanging this sequence between different procollage

114 lix-turn-helix DNA-binding motif was altered by exchanging two arginine residues for alanine residues

115 A novel model is that LTPs, by exchanging two different lipids, exploit one lipid gr

116 hibiting RAS-mediated NIH 3T3 transformation by exchanging VH and VL complementarity-determining regi

117 In this study, we generated chimeric viruses by exchanging viral genes between the thermostable TS09-

118 These ligands cannot be removed by drying or by exchanging with Cl- ions.