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1 lays a key role in homologous recombination, by facilitating 5'-to-3' resection of double-strand brea
4 tablish B cell fate and modulate cell growth by facilitating access of lineage-specific transcription
5 astuzumab links innate and adaptive immunity by facilitating activation of antigen-specific T cells.
6 ng potential to shape life history evolution by facilitating adaptation to fluctuating environments.
7 CA mutations stimulate lipid kinase activity by facilitating allosteric motions required for catalysi
8 at low copy loci but they may intensify RdDM by facilitating amplification of Pol IV-dependent siRNAs
9 hat PE enhances excitatory synaptic strength by facilitating an anti-Hebbian form of long-term potent
10 oliferation of oncogene expressing SVZ cells by facilitating an antiproliferative expression profile.
11 in protecting mitochondrial genome stability by facilitating an efficient repair of oxidative DNA dam
12 proteins can enhance protein phosphorylation by facilitating an interaction between a protein kinase
13 llin4-Ring Finger E3 ubiquitin ligase (CRL4) by facilitating an interaction between SAMHD1 and the su
14 e CN contributes to neuronal firing activity by facilitating AP generation and prolonging AP duration
15 cerebellum for adaptive control of behavior by facilitating appropriate output in a broad temporal w
18 n, IL-10 production plays a detrimental role by facilitating bacterial persistence via the same mecha
19 ignaling at unattached kinetochores not only by facilitating binding of BubR1 but also by enhancing C
20 that H3K4me1 has an active role at enhancers by facilitating binding of the BAF complex and possibly
21 ubsequent specialization can drive evolution by facilitating biological innovation and developmental
23 6 could provide significant clinical utility by facilitating both cancer staging and treatment monito
24 is essential for cardiovascular development by facilitating both mitochondrial respiration and TGFbe
25 several critical roles during the catalysis by facilitating both redox-coupled proton transfer proce
26 r long axis preserves epithelial homeostasis by facilitating both stress relaxation and isotropic gro
27 at activation of AhR sensitizes mice to NASH by facilitating both the "first hit" of steatosis and th
28 at a number of scales assists coral recovery by facilitating both the delivery of coral larvae to the
29 l and neuromorphological deficits of TS mice by facilitating brain plasticity and support the potenti
30 tic growth at larval neuromuscular junctions by facilitating Ca(2+) release from the endoplasmic reti
33 e for collagen XXIII in mediating metastasis by facilitating cell-cell and cell-matrix adhesion as we
34 portunities for the increase of biodiversity by facilitating challenging conditions for intraspecific
36 hannels and augments calcium current density by facilitating channel opening and increasing the numbe
37 d for the enhancement of electrical response by facilitating charge transfer processes of [Fe(CN)6](3
38 ponse to infection in several ways, that is, by facilitating clot formation, production of antimicrob
39 facial molecules facilitate tumor metabolism by facilitating CO2 venting and intracellular pH regulat
40 ancestry within individual studies but also by facilitating combined analysis of genetic data from m
41 nal significance in renal health and disease by facilitating communication between cells and protecti
42 plying N to leaf tissues for acclimation and by facilitating compensatory growth following drought.
43 s a systems-level understanding of infection by facilitating comprehensive analysis of transcriptomes
44 facilitate the maintained phase, for example by facilitating conduction of dilator signals upstream.
45 binding of unfolded OMPs to chaperones and, by facilitating conformational selection after release f
46 s have aimed to reduce the health inequities by facilitating connections with community resources.
47 in the eosinophil-mediated death of Colo-205 by facilitating contact between effector and target cell
48 mplemented fluorescence polarization imaging by facilitating cross-sectional inspection of tissue.
49 iates itself from other regulatory resources by facilitating crowd-sourced interpretation and annotat
50 nnate immune response to influenza infection by facilitating cytoprotective signals through c-Met sig
53 ys a critical role in heme synthesis pathway by facilitating delta-aminolevulinic acid production or
54 n of water accelerates the rate of catalysis by facilitating deprotonation of the hydrogen addition p
55 potential obstacles to replisome progression by facilitating DNA lesion bypass, extension of D-loops,
56 ular priming of lagging-strand DNA synthesis by facilitating DNA polymerase alpha function at replica
57 er, this study elucidates a new role of NCp7 by facilitating DNA-directed DNA synthesis during revers
60 CN) channels plays an important role in pain by facilitating ectopic firing and hyperexcitability in
61 tions, it augments protein affinity strongly by facilitating efficient myristate insertion and PI(4,5
62 e (RSA) impacts plant fitness and crop yield by facilitating efficient nutrient and water uptake from
63 onfers a significant physiological advantage by facilitating efficient replication and creating genet
64 merases (Pol) II, IV, and V serve dual roles by facilitating efficient translesion DNA synthesis whil
66 e management can improve short-term outcomes by facilitating either definitive care of the underlying
67 t aimed to reduce the burden of tuberculosis by facilitating either rapid sputum diagnosis or integra
69 that CaCCinh-A01 reduces ANO1 protein levels by facilitating endoplasmic reticulum-associated, protea
71 e lipid transfer activity of SR-BI, probably by facilitating entry steps along with other HCV entry c
73 onuclease activity on the lagging strand DNA by facilitating Exo1 loading onto a single strand gap at
74 tution p.Arg55His, but also affects splicing by facilitating exon 2 skipping, thus also being in effe
75 f double-strand break (DSB) ends, apparently by facilitating exonuclease digestion of nucleosome-boun
77 t Ca2+ and ATP modulate the Po predominately by facilitating extended bursting activity of the channe
79 volved in regulation of LC-PUFA biosynthesis by facilitating fad expression, probably through targeti
80 nent Nup42p and serves an important function by facilitating faster reacquisition of H(2)O(2) toleran
81 doknot fluctuations disrupt the binding site by facilitating fluctuations in the 5'-end of helix P1.
82 ty at stalled or collapsed replication forks by facilitating fork restart and limiting inappropriate
84 marneffei admissions, and may drive exposure by facilitating fungal growth or spore release in the en
85 hial nucleus (PBN) and it could be prevented by facilitating GABA(A) receptor signalling in the PBN w
87 GHS-R1b expression inhibits GHS-R1a function by facilitating GHS-R1a trafficking to the plasma membra
88 protects against dietary insulin resistance by facilitating glucose disposal and mitochondrial funct
89 tress dampens PFC glutamatergic transmission by facilitating glutamate receptor turnover, which cause
90 onsible for PK11195-mediated hCAR activation by facilitating hCAR interaction with coactivators and e
91 c histone modification and neuronal survival by facilitating HDAC3 activity and regulating its locali
92 up-regulation of key EGFR family members and by facilitating HGF-stimulated EGFR ligand secretion.
93 show that Baf200 plays an important function by facilitating homologous recombination-dependent proce
96 rimental role during C. pneumoniae infection by facilitating immune cell infiltration into the airspa
97 c overexpression of S-3B drove tumorigenesis by facilitating immune escape in a manner associated wit
98 of-the-art technology to study gene function by facilitating inducible expression in a timed and reve
99 in some ways to human infection, for example by facilitating infection of cells with low levels of CD
100 dhesion, independent of proteins or glycans, by facilitating interactions with complementary labeled
101 ve shown that Kremen1 inhibits Wnt signaling by facilitating internalization of the Kremen1-Dkk-Lrp5/
102 s the potential to improve surgical outcomes by facilitating intraoperative nerve identification, red
103 defectors nevertheless undermines altruism, by facilitating invasion of unrelated beneficiaries as p
104 strate that iron increases metastatic spread by facilitating invasion through expression of matrix me
105 ral anesthetics have revolutionized medicine by facilitating invasive procedures, and have thus becom
106 itment of T cell help shapes the Ab response by facilitating isotype switching and somatic hypermutat
107 nt from harmful effects of hydrogen peroxide by facilitating its degradation to oxygen and water.
108 d activation of TANK-binding kinase 1 (TBK1) by facilitating its dimerization and ability to phosphor
112 conformational change that stabilises RACO-1 by facilitating K63-linked ubiquitin chain formation, an
113 e repressors of plasma cell differentiation, by facilitating key transcriptional factor recruitment a
114 mors allows them to adapt to metabolic needs by facilitating lactate export or import depending on th
116 tentially make ensemble activity more sparse by facilitating lateral inhibition among MTs and/or enfo
117 mance on tested information, and indirectly, by facilitating learning from subsequent encounters with
118 undation species functioned as micro-refugia by facilitating less stress-tolerant lineages in severe
119 t the same time, Plvap has roles in immunity by facilitating leukocyte diapedesis at inflammatory sit
120 hat LINC00305 promotes monocyte inflammation by facilitating LIMR and AHRR cooperation and the AHRR a
121 ctions and contribute to V(D)J recombination by facilitating lineage- and developmental-stage-specifi
123 transport from the trans-Golgi network (TGN) by facilitating localized actin assembly at the TGN thro
124 t confer selective advantages to their hosts by facilitating localized DNA sequence evolution through
125 ver, isoflurane affected neuronal plasticity by facilitating long-term potentiation in the hippocampu
126 the pathogenesis of diabetic cardiomyopathy by facilitating MAPK activation, AT(1)R expression/signa
127 flammasomes regulate innate immune responses by facilitating maturation of inflammatory cytokines, in
128 functions during pre-TLR3 activation stages by facilitating maturation of TLR3 containing EE into LE
130 ec7 to activate Arf1 on the membrane surface by facilitating membrane insertion of the Arf1 amphipath
133 e bilateral cortical computational resources by facilitating movement-related desynchronization.
134 nt manner, thereby promoting mTORC1 activity by facilitating mTORC1 dimerization and mTORC1-Rag inter
135 served in animals and regulates neurogenesis by facilitating neural differentiation, yet its role in
139 s mRNA function--it changes the genetic code by facilitating non-canonical base pairing in the riboso
140 f PGAM5 promotes the expression of cytokines by facilitating nuclear translocation of NFAT and dephos
141 sed sensitivity to RAS-induced tumorigenesis by facilitating OIS escape, highlighting its physiologic
142 1 Lip5 (VSL) domain stimulates Vps4 function by facilitating oligomerization of Vps4 into its active
143 sumed a new significance because they might, by facilitating ongoing transmission, be a threat to the
144 netic protein 2 (BMP2) promotes PF formation by facilitating oocyte and granulosa cell development.
146 droxymethylation can control gene expression by facilitating or obstructing the action of transcripti
147 chondrial pore-dependent necrotic cell death by facilitating outer membrane permeability of the MPTP.
149 directly participate in microbial virulence by facilitating pathogen dissemination via interaction w
150 s can exacerbate killing of biofilm bacteria by facilitating penetration of toxic substances from the
151 ontribute to the development of liver cancer by facilitating persistent HBV replication, augmenting t
153 Annexin A2 helps reseal the plasma membrane by facilitating polymerization of cortical F-actin and e
154 an important role in targeted gene silencing by facilitating posttranscriptional and translational re
156 gically inert material, it confers virulence by facilitating proper formation of the A. fumigatus con
157 ocin system reduce the effects of xenophobia by facilitating prosocial behavior toward refugees.
158 uggesting that T(3) inhibits the Wnt pathway by facilitating proteasomal degradation of beta-catenin
159 e, STUB1, could influence metformin response by facilitating proteasome-mediated degradation of cycli
160 p plays a role in maintaining ER homeostasis by facilitating proteasome-mediated degradation of ER-re
161 t contributes to the robustness of the clock by facilitating protein complex formation and synchroniz
162 rmone auxin activates primary response genes by facilitating proteolytic removal of auxin/indole-3-ac
163 in) support cell resistance to CDC, probably by facilitating purging of the C5b-9 complexes by endocy
164 ides a protective mechanism for the parasite by facilitating purine and pyrimidine nucleotide pool ba
165 ty of ASS1 in cancers supports proliferation by facilitating pyrimidine synthesis via CAD (carbamoyl-
166 d the scope of carbonyl and iminyl chemistry by facilitating reactions with non-nucleophilic reagents
167 ins is required for TRAIL-induced cell death by facilitating receptor clustering and formation of the
168 led to an increase in KAR surface expression by facilitating receptor recycling between endosomal com
169 ion-independent interstrand crosslink repair by facilitating recruitment of lesion incision activitie
170 esponse to various cellular stresses in part by facilitating recruitment of the transcription machine
171 RAF3 dampened interleukin 2 (IL-2) signaling by facilitating recruitment of the tyrosine phosphatase
172 at enhances nucleotide excision repair (NER) by facilitating recruitment of the XPA protein to sites
174 onse to genotoxic stress and iron deficiency by facilitating redistribution of its small heterodimeri
175 , can contribute to informed decision making by facilitating reflection and discussion of personal co
177 in degradation of MARCH5 substrates, likely by facilitating release of ubiquitinated proteins from t
178 phase of inflammatory responses and does so by facilitating removal of inflammatory CC chemokines.
179 nces the outcome of an infection, presumably by facilitating replication and egress depending on the
180 ential for ensuring distal ureter maturation by facilitating retinoic acid signaling, Ret expression,
181 rect branching sponges mediate reef recovery by facilitating rubble consolidation, yet such natural p
182 ortant for Cbfb-MYH11-induced leukemogenesis by facilitating RUNX1 regulation of transcription and ce
183 ity is that cholesterol promotes myelination by facilitating signal transduction within the cell, bec
185 f breast cancers and promotes transformation by facilitating silencing of tumour suppressors and othe
186 w that CDK8 regulates p27 protein expression by facilitating Skp2-mediated p27 ubiquitination and deg
188 ssing, governs access to the MVC capsid gene by facilitating splicing and suppressing internal polyad
189 aine exerts its behavioral stimulant effects by facilitating synaptic actions of neurotransmitters su
191 progression may result in improved outcomes by facilitating targeted and timely treatment of AKI.
192 promotes atherosclerotic lesion development by facilitating the accumulation of oxidized low-density
193 isms include those that promote plant growth by facilitating the acquisition of limiting nutrients su
194 es in PDAC cell extravasation and metastasis by facilitating the adhesion to endothelial cells and tr
195 P335A mutation promotes its priming function by facilitating the alpha-helix to adopt an extended con
196 WD40 domain in PALB2, and drives DNA repair by facilitating the assembly of PALB2-containing HR comp
197 nal imaging can enhance the scope of studies by facilitating the assessment of biological alterations
198 in regulating IL-10 production in Th2 cells by facilitating the binding of IL-10-inducing transcript
199 l role for ANXA2 in NSCLC cell proliferation by facilitating the cell cycle partly through the regula
200 tions in drug discovery and cellular biology by facilitating the characterization of phenotypic diffe
201 odegenerative conditions may protect neurons by facilitating the clearance of accumulated sphingolipi
202 myosin VI that functions on the actin cones by facilitating the collapse of the C-terminal region on
204 date the contribution of genetics to disease by facilitating the creation of more accurate cellular a
205 f the complement cascade on its cell surface by facilitating the degradation of C3b, an opsonin, to a
206 sential for evading the host's immune system by facilitating the degradation of interferon regulatory
207 was previously implicated in APP processing by facilitating the degradation of the APP-cleaving beta
209 important inland and estuarine water bodies by facilitating the detection of point- and nonpoint-sou
210 GSTP protects the heart from I/R injury by facilitating the detoxification of cytotoxic aldehyde
211 profoundly altering the course of evolution by facilitating the development of aerobic respiration a
212 tions that allow intercellular communication by facilitating the diffusion of small molecules from ce
213 timulates the maximum rate of ATP hydrolysis by facilitating the dimerization of nucleotide-binding d
214 the specificity of T-cell effector function by facilitating the directional release of cytokines and
215 le in the pathogenesis of inhalation anthrax by facilitating the dissemination of Bacillus anthracis
216 promotes STAT5 accessibility at promoter DNA by facilitating the dissociation of the linker histone H
217 cooperates with PKC to drive LTD expression by facilitating the effect of PKC on the dissociation of
218 that CTCF promotes HSV-1 lytic transcription by facilitating the elongation of RNA Pol II and prevent
219 n the removal of carbon dioxide from tissues by facilitating the exchange of chloride and bicarbonate
220 ibutes to intracellular pH (pHi ) regulation by facilitating the exchange of extracellular Cl(-) for
221 ibutes to intracellular pH (pHi ) regulation by facilitating the exchange of extracellular Cl(-) for
222 es the hypermutator effect of Poldelta-R696W by facilitating the extension of mismatched primer termi
223 del in which the proteins promote adsorption by facilitating the formation of a negatively curved, ra
224 -magnitude increase in membrane permeability by facilitating the formation of larger transmembrane po
227 lator of a number of physiological processes by facilitating the formation of multiprotein signaling
228 hus, Foxp3 poises its targets for repression by facilitating the formation of repressive chromatin in
230 e is found to greatly enhance ice nucleation by facilitating the formation of special topological def
231 ependent checkpoint signaling in human cells by facilitating the generation of RPA-bound single-stran
232 s as a master regulator of early development by facilitating the genome-wide establishment of overlap
234 cleus and suggest a possible common function by facilitating the horizontal transfer of genes between
235 resolved questions about microbial pathogens by facilitating the identification of genes underlying e
236 genome has contributed to post-GWAS studies by facilitating the identification of the functional tar
237 tivity of hyperthermophilic proteins, likely by facilitating the increasing flexibility required for
238 ontribute to immunological memory in T cells by facilitating the induction of nearby inducible regula
239 fficient exploration of complex environments by facilitating the inspection of new locations in real
240 RECQ5 helicase promotes TOP1 SUMOylation by facilitating the interaction between PIAS1, SRSF1 and
241 ta targets the E3 ligase RNF8 to DNA lesions by facilitating the interaction between RNF8 and its ups
242 regulating the stability of PDE transcripts by facilitating the interaction between the exoribonucle
243 how that WIZ regulates global H3K9me2 levels by facilitating the interaction of G9a with chromatin.
244 on the LPA1 receptor promotes IEC migration by facilitating the interaction of Galphaq with PLC-beta
245 e and orientation of enzymatic components or by facilitating the interface between enzymes/cofactors
247 d a role during the infancy of the RNA world by facilitating the nonenzymatic replication of genomic
248 critical step in the viral replication cycle by facilitating the nuclear export of intron-containing
249 is protein plays a key role in HIV infection by facilitating the nuclear import of the pre-integratio
250 tions contribute to the spliceosome dynamics by facilitating the physical rearrangements of the splic
251 ion of Ena1 expression after cationic stress by facilitating the plasma membrane recruitment of the m
252 linked to tumor progression in breast cancer by facilitating the processes of invasion, migration, an
253 e dark adaptation of cones, first, directly, by facilitating the processing of chromophore in cones,
254 igh folate intake may promote carcinogenesis by facilitating the progression of established neoplasia
255 metastatic breast cancer cells in the brain by facilitating the re-epithelialization of metastatic b
257 ence and inhibiting worker reproduction, and by facilitating the recognition and policing of worker-l
258 an important role in the DNA damage response by facilitating the recruitment of 53BP1 to sites of DNA
259 pivotal role in maintaining genome integrity by facilitating the recruitment of kinetochore and siste
260 al switches to promote cox-2 gene expression by facilitating the recruitment of MSK1 and Cdk9 to the
261 for repair of DNA ICLs at telomeres, likely by facilitating the recruitment of repair proteins simil
262 on of the phagophore into the autophagosome, by facilitating the recruitment of the Atg12-5-16L1 comp
263 , both by accelerating fibrin generation and by facilitating the regulatory anticoagulation mechanism
264 e-lapse imaging shows that the mutations act by facilitating the release of the L-form from its walle
266 e possibility of genetic improvement, either by facilitating the selection of candidate genes for hyp
267 an elaborate translational control mechanism by facilitating the sequestration of germ cell mRNAs int
268 m might operate in the plant stress response by facilitating the stress-induced transcription of gene
269 contribute to the comparative genomics field by facilitating the study of the origin of new genes and
273 re it links transcription and nuclear export by facilitating the transfer of mature mRNPs from the nu
274 An initial progenitor could recruit others by facilitating the transformation of one or more neighb
275 on 4B, promotes liver fibrosis and cirrhosis by facilitating the transforming growth factor beta (TGF
276 lanktonic to the biofilm mode of growth, and by facilitating the transition of biofilm cells to a hig
277 e expression during myogenic differentiation by facilitating the transition of promoter sequences fro
278 role in DNA damage response (DDR) signaling by facilitating the translocation of several DDR mediato
279 ays a vital role in maintaining lens clarity by facilitating the transport of water across lens fiber
280 s shown to modulate the chemotactic response by facilitating the uptake of 4-hydroxybenzoate, which l
282 of Reelin signaling that acts predominantly by facilitating the VLDLR-Dab1 axis to direct neuronal m
283 ation and minimizes their cytoplasmic levels by facilitating their ubiquitination by the E3 ligase SC
284 ed as adjuncts to mitigate these limitations by facilitating tighter coil packing and preventing coil
285 ppresses Ras-induced cellular transformation by facilitating Tip60-mediated degradation of Dmnt1 and
287 ns as a negative regulator of TLR4 signaling by facilitating TLR4 endocytic trafficking in macrophage
288 stocyst formation rate in human SCNT embryos by facilitating transcriptional reprogramming, allowing
290 tating the Na2 site potentiated K(+) binding by facilitating transition to the inward-facing state.
291 antiproliferative and prosurvival properties by facilitating translation of mRNAs encoding for the cy
292 s are proposed to enhance Cu phytoextraction by facilitating transport across the endodermis, ostensi
293 ulates NMDAR subunit composition at synapses by facilitating transport of GluN2B from the ER to synap
295 alter the properties of kinesin-13, in part by facilitating unique protein-protein interactions.
297 nhance the potency of DNA vaccines, possibly by facilitating uptake of the plasmid by antigen-present
298 essin (AVP) has a key role in osmoregulation by facilitating water transport in the collecting duct.
300 flammatory cells multitask at the wound site by facilitating wound debridement and producing chemokin
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