ライフサイエンスコーパス: by use of

1 genome-wide association studies was imputed by use of 1000 Genomes data.

2 nd Arabidopsis (Arabidopsis thaliana) plants by use of (42)K radiotracing, electrophysiology, pharmac

3 Rate constants were calculated by use of a 3-compartment model.

4 By use of a adenoviral eIF5A shRNA, we have achieved an

5 A Mediterranean diet score was created by use of a baseline-validated food-frequency questionna

6 veratrylene-type L ligands can be stabilized by use of a bis-N-heterocyclic carbene as an auxiliary c

7 bital and one of four bumetanide dose levels by use of a bivariate Bayesian sequential dose-escalatio

8 risedronate (35 mg/week) or matched placebo by use of a block randomisation schedule via a web-based

9 Hormones were assessed by use of a blood assay.

10 e, pimeloyl-ACP methyl ester to pimeloyl-ACP by use of a catalytic triad, each member of which was es

11 ion, as well as in vitro metabolism of TPHP, by use of a chicken embryonic hepatocyte (CEH) screening

12 composed of HA and clay minerals was studied by use of a coated-wall flow reactor and cavity-enhanced

13 drug use (IDU) to HBV and HCV disease burden by use of a cohort method that recalibrated individuals'

14 eneic stem cell transplantation twice weekly by use of a commercial GM enzyme-linked immunosorbent as

15 non-inferiority of no-testing versus testing by use of a composite outcome of arrhythmic death or fai

16 By use of a computer-based algorithm, men were randomly

17 By use of a computer-generated randomisation sequence, w

18 e on the wait list and after LT were modeled by use of a Cox model that incorporated transplantation

19 activities of multiple S. salivarius strains by use of a deferred-antagonism test showed that S. sali

20 IBD or a single health care contact followed by use of a drug to treat IBD.

21 rated with an in-plane charge current simply by use of a FM/NM bilayer with magnetization collinear t

22 sal nerve analysis by 2 masked observers and by use of a fully automated method; wide-field mosaics o

23 reducing depression at the population level by use of a fully automatised system with the potential

24 table device were limited by the pain caused by use of a high-energy single biphasic shock (BPS).

25 tial identification of the bacterial species by use of a kmer-based approach.

26 UBD was identified by use of a MAPPIT (mammalian protein-protein interactio

27 We did the random assignment by use of a minimisation method with a random element, a

28 By use of a more clinically relevant protocol, 0.3 or 1

29 PS-II inhibitor isoproturon was investigated by use of a Myriophyllum spicatum bioassay.

30 itrate intake from vegetables was calculated by use of a newly developed comprehensive database.

31 By use of a noncovalent double mutant (T790M/L858R and T

32 By use of a novel phylogenetic analysis that avoids subt

33 By use of a pairwise analysis strategy, intramolecular h

34 Data were collected by use of a patient questionnaire and primary care and h

35 vironment of a nanometre-scale light emitter by use of a photonic cavity can significantly enhance it

36 ropofol binding sites in a muscle-type nAChR by use of a photoreactive analog of propofol, 2-isopropy

37 ountries were compared with those in England by use of a quantile regression analysis.

38 and can only be extended to longer distances by use of a quantum repeater, a device that performs ent

39 nd surveillance practices were also assessed by use of a questionnaire.

40 Effect estimates were pooled by use of a random-effects meta-analysis.

41 By use of a reliable enzymatic assay together with X-ray

42 lved in the RBE, we conducted a second study by use of a repeated-bout paradigm.

43 Participants were allocated in a 1:1 ratio by use of a secure web-based computer-generated randomis

44 uncertainty, which is not readily explained by use of a simple prior favouring peripheral locations.

45 types allows the testing of T-cell responses by use of a simple, approachable technique and points to

46 trategy for creating QCM-based sensor arrays by use of a single sensor to provide multiple responses

47 de 1-2 carcinoid tumours or pancreatic NETs, by use of a single-group, two-stage design.

48 AD-Ep enables convenient sample introduction by use of a slip layer as well as easy product analysis

49 the effect of hospital competition (measured by use of a spatial competition index [SCI], with a scor

50 on for >/=24 h) were randomly assigned (1:1) by use of a stratified block randomisation via restricte

51 By use of a structure-based computational method for ide

52 shifts are assigned to specific metabolites by use of a tolerance limit.

53 structured interviews were conducted, guided by use of a topic guide developed with input from patien

54 togenerated oxygen was measured in real-time by use of a two-electrode cell design.

55 cipants free of any cardiovascular disorders by use of a validated ex-vivo radiotracer assay that inv

56 solution is flown over the electrode surface by use of a wall-jet configuration.

57 Random assignment was done by use of a web-based automated randomisation system, st

58 racted from aged oil sands-influenced waters by use of acid precipitation, and the mixture was fracti

59 g well-shielded special nuclear materials is by use of active interrogation using an external radiati

60 eir content of (148)Gd, (173)Lu, and (146)Pm by use of alpha- and gamma-spectrometry.

61 r may have a bigger benefit than that gained by use of an active compound vs a placebo.

62 pulses can be reconstructed in a single shot by use of an angle-multiplexed spatial-spectral interfer

63 Randomisation (1:1) was by use of an audited online system; group allocation was

64 field mosaics of subbasal nerve architecture by use of an automated method; and ocular surface touch

65 ed 1:1 to undergo PCI or a placebo procedure by use of an automated online randomisation tool.

66 By use of an excess amount of ketene, a distinct reactio

67 By use of an in vivo expression technology (IVET)-based

68 By use of an infectious SAT2 cDNA clone, 10 structurally

69 By use of an interactive response technology using fixed

70 , and anatomic site (pleural vs peritoneal), by use of an interactive voice or web system, to receive

71 imens, patients were randomly assigned (1:1) by use of an interactive voice response system with a bl

72 ombinant adenoviral RSV vaccine administered by use of an intramuscular prime-intranasal boost regime

73 ere diagnosed with a major motility disorder by use of an STM than with SWS in the development set (3

74 rapy on lipoproteins and their protein cargo by use of an unbiased bottom-up proteomics approach in p

75 7] mum vs 331 [94] mum; P = .004, determined by use of an unpaired t test).

76 nces in chemical exchange rates are measured by use of an unstructured reporter peptide, YPI.

77 nt for ophthalmologists was primarily driven by use of anti-vascular endothelial growth factor (anti-

78 tion perovskite thin films are normally made by use of antisolvent protocols.

79 By use of artemisinin 1 as the starting material, two ne

80 changes in the autophagic flux (as assessed by use of bafilomycin A1) occurred either when TPC1 or T

81 ted from Cox models and internally validated by use of bootstrap and cross-validation.

82 tigated the trafficking properties of GPRC6A by use of both a classical antibody feeding internalizat

83 Next, parametric images were generated by use of both Logan graphic analysis with various linea

84 Analysis of the IRES region in vitro by use of both the TCV gRNA and reporter constructs did

85 high prevalence among PLHIV) by age and sex by use of case-finding algorithms.

86 Clara cell antigen 10 (CC10)(+) Clara cells by use of cell-type-restricted recombinant Adeno-Cre vir

87 tigators were masked to treatment assignment by use of central randomisation and coded drug supply.

88 of this concept when considering risks posed by uses of chemicals, and provide examples of how functi

89 ucted with high levels of enantioselectivity by use of chiral rhodium(II) catalysts.

90 cal IgA antibodies compared to those induced by use of cholera toxin as a positive-control adjuvant.

91 By use of claims data from Medicare beneficiaries in the

92 of infection was not significantly affected by use of CMV prophylaxis (P=0.16) but death from cardio

93 chanism for overcoming neutralization escape by use of cocktails of cross-neutralizing monoclonal ant

94 as possible to identify a number of proteins by use of collision-induced dissociation tandem mass spe

95 nd cognitive deficits were randomly assigned by use of computer-based allocation to receive 6 weeks o

96 with women without reproductive risk factors by use of conditional logistic regression.

97 ons (90/1051 [9%] vs 42/1051 [4%]; p<0.0001) by use of conservative diagnostic definitions.

98 method; and ocular surface touch sensitivity by use of contact esthesiometry.

99 Mass spectrometry imaging by use of continuous-flow liquid microjunction sampling

100 ihydrogen complexes in tetrahydrofuran, and, by use of conversion equations, in other solvents.

101 uptake values obtained with AC were analyzed by use of correlation analysis and Bland-Altman limits o

102 -up were compared across quartiles of GDF-15 by use of Cox analyses adjusted for clinical characteris

103 The model was parameterised by use of data for 10 278 patients from the national Dut

104 e assessed changes in rotavirus epidemiology by use of data from eight active surveillance hospitals.

105 By use of data-dependent product ion scans, multiple dru

106 l accessory proteins Vpu and Nef were sought by use of deletion viruses and single gene overexpressio

107 Chromatin analysis of T cells made tolerant by use of different in vitro and in vivo approaches reve

108 and increase sensitivity of detection mainly by using of different assay formats, immobilization stra

109 min(-1) in a N2 atmosphere and characterized by use of differential scanning calorimetry (DSC) and th

110 xperimental axial profiles (Z-axis) were fit by use of diffusion-controlled and surface-controlled ev

111 ong MSM relative to adult men was calculated by use of direct age-stratification.

112 eous setting can be facilitated tremendously by use of DNP-enhanced solid-state NMR spectroscopy.

113 terminal to its single catalytic domain and, by use of domain deletions, binding studies, and enzyme

114 fforts to intensify pharmacological blockade by use of dual inhibitors that interfere with the renin-

115 By use of E-64 as a lead, three successive generations o

116 ransformation on MoS2 surfaces was confirmed by use of electron microscopy and spectroscopic techniqu

117 By use of empirically well-constrained computer models d

118 ycan structural features (epitopes) provided by use of established monoclonal antibodies allows the s

119 By use of ethylene carbonate and propylene carbonate, ne

120 ity of experimental treatments was concealed by use of everolimus and placebo that were identical in

121 vities of daily living) or death up to 2025, by use of evidence-based age-specific, sex-specific, and

122 This is nearly twice that obtained by use of existing programs that make use of centroiding

123 By use of exoglycosidase sequencing, in conjunction with

124 pecific dropout rates and amplification bias by use of external RNA spike-ins.

125 By use of fast-scan cyclic voltammetry, CNT-coated niobi

126 hat n-3 polyunsaturated fatty acids (PUFAs), by use of fat-1 transgenic mice and oral administration

127 manganese, selenium, and zinc were measured by use of Flow-Injection-Inductively-Coupled-Plasma-Mass

128 By use of fluorescent reporters, we show that Myxococcus

129 rated into proteins for tracking and imaging by use of fluorogenic tetrazines that become strongly fl

130 antibody assay using human complement (hSBA) by use of four meningococcal serogroup B test strains ex

131 We identified diagnostic events by use of general practitioners' records, hospital disch

132 Normograms were estimated by use of generalized additive models for location, shap

133 Diabetes was defined by use of glucose concentrations, self-report, or medica

134 chemistry, and optimizing culture conditions by use of growth curve assays with a fractional factoria

135 By use of Hg isotope tracers added in situ to the mesoco

136 the opposite transformation is also possible by use of high-power lasers.

137 This was achieved by use of high-resolution (c. 5 mum) synchrotron radiati

138 induce humoral and cellular immune responses by use of highly attenuated and safe vaccine backbones.

139 By use of hospital-level variation among regional index

140 By use of human and rat neuronal cell lines (SK-N-SH and

141 her deprotection of these isolated compounds by use of hydrochloric acid (12 N) in methanol afforded

142 from cardiac arrest to discharge, stratified by use of hydrocortisone, using a Japanese health-insura

143 By use of hydrogen/deuterium exchange and biochemical an

144 atment allocations, and masking was achieved by use of identical opaque capsules.

145 from phosphoproteins is commonly facilitated by use of immobilized anti-pY antibodies prior to phosph

146 lular nuclei and neurons in the hypothalamus by use of immunohistochemistry and in situ hybridization

147 The strong link to a task paradigm provided by use of independent component analysis is a potential

148 rkers identified from the discovery analysis by use of independent immunoassays for each biomarker.

149 Means were compared by use of independent two-tailed t tests.

150 al in patients with hepatocellular carcinoma by use of individualised, preoperatively assessed charac

151 all interfering RNA transfection in vitro or by use of inhibitor of Wnt production in vivo led to an

152 Incident AF was ascertained by use of International Classification of Diseases, Nint

153 sprayed industrial polymers may be moderated by use of ion mobility spectrometry (IMS) and MS in seri

154 ct low-affinity peptide-protein interactions by use of ion mobility, electron transfer dissociation,

155 By use of iterative design aided by predictive models fo

156 Outcomes were compared between the groups by use of Kaplan-Meier and descriptive statistics.

157 d accurately identified to the species level by use of kmer comparisons and MLST.

158 erve density and subbasal nerve architecture by use of laser-scanning in vivo confocal microscopy; su

159 Targeting (225)Ac(3+) by use of ligands conjugated to traditional bifunctional

160 troviral therapy or AIDS onset were analysed by use of linear or fractional polynomials mixed models

161 breast cancer at an early stage are detected by use of mammography.

162 ease in risk of these adverse fetal outcomes by use of Mantel-Haenszel methods.

163 By use of messenger ribonucleoprotein (mRNP) immunopurif

164 g properties in conductivity and topography, by use of metal-layer constrained recovery.

165 enerated, permuted-block schedule stratified by use of methotrexate at baseline (0, >0 to <12.5 mg/we

166 By use of mice in which the PKD2L1 promoter drives expre

167 By use of microbiota profiles for risk assessment and ma

168 alised treatment pathways could be developed by use of miR-122, HMGB1, and full-length K18 at hospita

169 pendent suboptimal mutation incorporation or by use of mixed repair templates.

170 By use of moderate electrodeposition conditions such as

171 By use of molecular dynamics simulations we trap a secon

172 cells and proteins in subcellular locations by use of multiplexed antibody staining protocols.

173 ed, PCa-free comparison cohort (n = 187,785) by use of multivariable Cox proportional hazards regress

174 By use of multivariate analysis, shift work (odds ratio

175 variables of interest with overall survival by use of multivariate Cox regression: MELD-sodium (MELD

176 ed and predictors of decline were identified by use of multivariate models.

177 as a tool for gene silencing can be enhanced by use of mutant plants with increased production of 24-

178 The approach is introduced by use of myoglobin from four meats: beef, pork, horse a

179 proteins to different subcellular locations by use of nanobody-fusion proteins.

180 Here, by use of native elongating transcript sequencing (NET-s

181 Subjects were grouped by use of neoadjuvant RT.

182 If people diagnosed by use of new diagnostics would have received empirical

183 e corresponding nitro compounds is described by use of nonanebis(peroxoic acid).

184 ntified, and targeting specificity was shown by use of noninserting variants.

185 Here, by use of novel and highly selective JNK inhibitors, we

186 Lightweighting of automobiles by use of novel low-cost, high strength-to-weight ratio

187 t loss can be maintained in some individuals by use of novel written material with occasional brief n

188 or guardians) were randomly assigned (1:1), by use of numbered sealed envelopes containing a randomi

189 es of four, six, and eight) with concealment by use of opaque, sequentially numbered, sealed envelope

190 Randomisation was stratified by use of opioids for prostate cancer-related pain at sc

191 he risk associated with PMS was not modified by use of oral contraceptives or antidepressants but was

192 hown strong associations with those obtained by use of other early indices of severity and outcome.

193 proteins than have been reported previously by use of other methods and additives, such as that obta

194 ulate matter measured at different size cuts by use of PbB concentrations from the National Health an

195 By use of pdcd5 mutants, we here demonstrate that these

196 er early or delayed antiretroviral treatment by use of permuted block randomisation, stratified by si

197 By use of physiologically-based pharmacokinetic modeling

198 nducting propensity score analysis adjusting by use of platelets, fresh frozen plasma, and cryoprecip

199 the National Cancer Data Base and stratified by use of PORT (>/= 45 Gy).

200 the present work on species identification, by use of predictive tools, we determine peptide markers

201 ectrum disorder were randomly assigned (1:1) by use of probabilistic minimisation, controlling for tr

202 Outcomes were compared by use of propensity score adjustment to account for bas

203 three users of other glucose-lowering drugs by use of propensity scores.

204 the risk of subsequent disability worsening by use of proportional hazards models that included OCT

205 ltation on infection acquisition and outcome by use of proportionate morbidity ratios.

206 ee type-B ARR DNA-binding motifs, determined by use of protein-binding microarrays, were enriched at

207 By use of protocols that preserve proximal retinal neuro

208 de-noised, cleaned of chimeras, and analysed by use of QIIME software (version 1.8.0).

209 class discrimination, was 100% as determined by use of quadratic discriminant analysis (QDA).

210 Removal of immunoglobulins by use of Rag-deficient mice restored Ad5 transduction t

211 olyphosphate quantification can be shortened by use of Raman microscopy from days to hours and, addit

212 intervals for each predictor were calculated by use of random effects models.

213 Trials Unit telephone randomisation service by use of random number generators.

214 nalysis we estimated the summary effect size by use of random-effects and fixed-effects models, the 9

215 l admissions and deaths per disease category by use of random-effects models.

216 ive pressure exerted on parasite populations by use of RDTs for diagnosis of symptomatic cases.

217 Detection was dramatically improved by use of real-time immuno-polymerase chain reaction (PC

218 d for the construction of calibration curves by use of reference solutions.

219 By use of regression analyses adjusted for demographics,

220 y our algorithm can subsequently be analyzed by use of relevant specialized software.

221 itive fluid balance, however, was attenuated by use of renal replacement therapy.

222 We recruited the study population by use of respondent-driven sampling and did the baselin

223 After stratifying by use of RGP lenses for orthokeratology, storing lenses

224 oRNAs, sensing of changes in the environment by use of riboswitches (RNAs that change shape in respon

225 es) to estimate 30 day in-hospital mortality by use of risk adjustment measures including age, sex, a

226 itate single cell cultures that are achieved by use of ROCK (Rho kinase) inhibitors.

227 By use of SBDD, the flap pocket of Plm II has been disco

228 aemic control in the treatment of depression by use of selective serotonin reuptake inhibitors or psy

229 indicators of quality (e.g., dietary fiber) by use of self-report or objective biomarkers of intake.

230 anslated region as well as in human NK cells by use of sense and antisense miR-183.

231 s were followed up for a median of 22 months by use of serial systemic, ophthalmic, and imaging exami

232 Donations containing HEV were characterised by use of serology and genomic phylogeny.

233 Findings were validated by use of sex-specific CDVs and parallel measurements of

234 of the human and mouse 5-HT3A subunits, and by use of site-directed mutagenesis, we have identified

235 By use of small angle x-ray scattering, we explore the s

236 study data were linked with Medicare claims by use of Social Security numbers.

237 al estimates to sophisticated quantification by use of software.

238 e to compensate for any drift between images by use of software.

239 By use of solid state (13)C NMR, three rotating fragment

240 This instability may be controlled by use of solid/gas synthetic techniques that enable the

241 By use of spleens from Escherichia coli infected mice, s

242 sease by use of STATseq and three (9%) of 32 by use of standard genetic testing (p=0.0002).

243 assessed as prespecified secondary outcomes by use of standardised tests at baseline and months 6, 1

244 nfants were diagnosed with a genetic disease by use of STATseq and three (9%) of 32 by use of standar

245 n-like components can be desorbed and eluted by use of stepwise elution as progressively greater pH v

246 By use of stillbirths as cases and a sample of matched l

247 mber of GPCR drugs that have been discovered by use of structural information that are in clinical de

248 this decomposition pathway can be inhibited by use of substrates in which the olefin bears a beta-me

249 Finally, by use of surface plasmon resonance (SPR) measurements,

250 e TTV load was assessed in 342 serum samples by use of TaqMan real-time polymerase chain reaction, al

251 e used to calculate toxic equivalents (TEQs) by use of TEFs for fishes used by the WHO and TCDD equiv

252 Hourly emissions are created for CMAQ by use of temporal profiles applied to annual emission t

253 Patients categorized as low-risk by use of the ATRIA score were not necessarily low-risk,

254 734), on cognitive function at 24 mo of age by use of the Bayley scales of infant and toddler develo

255 nded clinical isolates from our institution, by use of the BioTyper software, accurate species-level

256 action was achieved directly on the filament by use of the carburized filaments.

257 By use of the cumulative incidence, we estimated 5- and

258 By use of the Danish national registers, we followed up

259 Generation of PK profiles by use of the device was initially performed with fluore

260 The more generalized concept is demonstrated by use of the Fc(0/+) (Fc = ferrocene) reversible proces

261 Sexual functioning was assessed by use of the Female Sexual Function Index.

262 ata are reported as pooled odds ratios (ORs) by use of the generic inverse variance method with the u

263 y, effects on production of steroid hormones by use of the H295R steroidogenesis assay, and sex stero

264 re examined for Ah receptor-mediated potency by use of the H4IIE-luc bioassay, effects on production

265 By use of the heterologous transcription activator LexA-

266 mical exchange correction factor, determined by use of the HX data from the reporter peptide, is then

267 onal to the magnetic field that is generated by use of the laser pulse without rf initialization.

268 om onset and at months 4, 8, 12, 18, and 24, by use of the modified Rankin scale (mRS).

269 nd, the modulation of endocannabinoid levels by use of the phytocannabinoid cannabidiol and selective

270 xpression throughout the embryo were studied by use of the Porcupine inhibitor C59, which interferes

271 of precise dental restoration is achievable by use of the proposed method.

272 ominal and femoral ATBF were studied in vivo by use of the radioactive xenon washout technique after

273 gged recombinant Orsay virus, were generated by use of the reverse genetics system.

274 s of ASCVD before enrollment in the registry by use of the SAFEHEART risk equation, the modified Fram

275 7 mutants in this codon range were evaluated by use of the same recombinant phenotyping system and ex

276 able binding potential (BPND) was calculated by use of the simplified reference tissue model with the

277 Inhibition of vacuolar H(+)-ATPases by use of the specific inhibitor bafilomycin A1 abrogate

278 toxin type B (BoNT/B) and another BoNT that, by use of the standard mouse bioassay, could not be neut

279 of the resulting target ROIs were evaluated by use of the standardized uptake value ratio for (18)F-

280 (123)I-ABC577 binding was quantified by use of the standardized uptake value ratio, which was

281 assigned genotypic sensitivity scores (GSSs) by use of the Stanford HIV Database version 6.3.1: a glo

282 Furthermore, by use of the triple-color total internal reflection flu

283 By use of the tryptophan (Trp) analog probe 2,7-diaza-tr

284 ng new class of near-infrared devices where, by use of the unusual band structure properties of GaAsB

285 partial, or complete response, were assessed by use of the urticaria activity score, physician and pa

286 elf-referral (with diagnosis made by parents by use of the validated Molluscum Contagiosum Diagnostic

287 progression, and regression of AMD (assessed by use of the Wisconsin Age-Related Maculopathy Grading

288 y, and much has been learned in recent years by use of these techniques.

289 ul scope, is demonstrated for the first time by use of this catalyst, and is competitive with the mos

290 By use of this information, the structure-activity relat

291 By use of this integrative approach, both the key commun

292 siological) and six clusters of risk factors by use of three inputs: risk factor exposure, relative r

293 computer generated, blocked, and stratified by use of ticagrelor or prasugrel, type of acute coronar

294 icient protocols discussed herein are marked by use of UVA LEDs (365 nm), which have reduced the reac

295 mptoms, and marital adjustment were assessed by use of validated questionnaires.

296 Pathogens are recognized by hosts by use of various receptors, including the Toll-like rec

297 us among harbor seals of northwestern Europe by use of various samples collected during the outbreak.

298 t, we increased SIRT1 levels directly in NAc by use of viral-mediated gene transfer and observed an i

299 moting cocaine-elicited behavioral responses by use of viral-mediated gene transfer: we show that ove

300 st identified in a multiplex family with FTD by use of whole-exome sequencing.