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1 lently label a nonactive site residue in the cAMP-dependent protein kinase.
2 the protein kinases Akt and GSK3beta but not cAMP-dependent protein kinase.
3 rominent and was shown to depend on G(s) and cAMP-dependent protein kinase.
4 ctivation of the proapoptotic protein BAD by cAMP-dependent protein kinase.
5 /Ser(67) inhibitor-1 is a poor substrate for cAMP-dependent protein kinase.
6 ein kinase family members, Akt-1, PDK-1, and cAMP-dependent protein kinase.
7 phosphorylation of alpha-Ser(485/491) by the cAMP-dependent protein kinase.
8 volving G G proteins, adenylate cyclase, and cAMP-dependent protein kinase.
9 and docking (D/D) domain of the cyclic AMP (cAMP)-dependent protein kinase.
10 (i) proteins to control the adenylyl cyclase-cAMP dependent protein kinase A (PKA) pathway to regulat
12 tion between cyclic adenosine monophosphate (cAMP)-dependent protein kinase A (PKA) and A-kinase anch
13 ion of adenosine 3',5'-cyclic monophosphate (cAMP)-dependent protein kinase A (PKA) is sufficient and
14 In this paper, we report that cyclic AMP (cAMP)-dependent protein kinase A (PKA) promotes acinus f
15 uires cyclic adenosine 3', 5'-monophosphate (cAMP)-dependent protein kinase A (PKA) signaling, raisin
16 at Tregs use cyclic adenosine monophosphate (cAMP)-dependent protein kinase A pathway to inhibit HIV-
18 d to determine the role of PPT intracellular cAMP-dependent protein kinase A (cAMP-PKA) in the regula
24 s of two major components of cAMP signaling, cAMP-dependent protein kinase A (PKA) and adenylate cycl
25 ity is known to depend on phosphorylation by cAMP-dependent protein kinase A (PKA) and CFTR-ATPase ac
26 was found to be differentially modulated by cAMP-dependent protein kinase A (PKA) and exchange prote
27 DA D(1) receptor(D(1)R) signaling, including cAMP-dependent protein kinase A (PKA) and extracellular
28 C1 and PDE4 modulate NDE1 phosphorylation by cAMP-dependent protein kinase A (PKA) and identify a nov
29 vates dopamine D2 autoreceptors to stimulate cAMP-dependent protein kinase A (PKA) and protein kinase
30 regulated through Ser-133 phosphorylation by cAMP-dependent protein kinase A (PKA) and related kinase
31 lpha catalytic subunit and comparable global cAMP-dependent protein kinase A (PKA) enzyme activity.
34 factor that integrates signaling through the cAMP-dependent protein kinase A (PKA) in many eukaryotes
40 endent changes in the activity levels of the cAMP-dependent Protein Kinase A (PKA) on the formation o
42 gnificant role has been ascribed to the cAMP/cAMP-dependent protein kinase A (PKA) signaling pathway
43 ith both receptors: Binding to CXCR4 induces cAMP-dependent protein kinase A (PKA) signaling, which i
47 on, localization and regulation of different cAMP-dependent protein kinase A (PKA) subunits account f
49 A single molecule of the catalytic domain of cAMP-dependent protein kinase A (PKA) was attached to a
50 phosphorylation was blocked by inhibitors of cAMP-dependent protein kinase A (PKA), an enzyme involve
51 ferentiation requires activation of CREB and cAMP-dependent protein kinase A (PKA), but the role of P
54 on of Ksp1 is partially activated by the Ras/cAMP-dependent protein kinase A (PKA), which is another
55 omotes nucleotide excision repair (NER) in a cAMP-dependent protein kinase A (PKA)-dependent manner.
56 with cardiac ryanodine receptors (RyR2), and cAMP-dependent protein kinase A (PKA)-dependent phosphor
57 n of Rap1 by cyclic AMP (cAMP) can occur via cAMP-dependent protein kinase A (PKA)-independent and PK
58 was oligomycin-insensitive and contingent on cAMP-dependent protein kinase A (PKA)-induced lipolysis.
65 , a specific isoform of the second messenger cAMP-dependent protein kinase A (PKAalpha) rapidly phosp
66 onical pathway involving both an increase in cAMP-dependent protein kinase A activity and the GLI3R t
67 tion, but inhibition of either calmodulin or cAMP-dependent protein kinase A activity blunted the hyp
69 based community maps of the kinase domain of cAMP-dependent protein kinase A allow for a molecular ex
70 ing a yeast two-hybrid screen, we identified cAMP-dependent protein kinase A anchoring protein 95 kDa
72 T, and dmLT promote human Th17 responses via cAMP-dependent protein kinase A and caspase-1/inflammaso
73 7/gp78-reconstituted system with and without cAMP-dependent protein kinase A and PKC, two liver cytos
74 n of recombinant mouse PDE3A with PKB/Akt or cAMP-dependent protein kinase A catalytic subunits leads
75 ,3-a]quinoxalin-1-one but was insensitive to cAMP-dependent protein kinase A inhibition with H89 and
76 diating the dual effects of PTH, whereas the cAMP-dependent protein kinase A pathway appears to predo
80 h-affinity state and activated the canonical cAMP-dependent protein kinase A signaling pathway in car
81 40 through the activation of MAPK/Erk1/2 and cAMP-dependent protein kinase A signaling, respectively.
82 Reduction in GluR1 phosphorylation at its cAMP-dependent protein kinase A site by the synthetic pe
84 cyclase VI and the catalytic subunit of the cAMP-dependent protein kinase A, were predicted as direc
85 increased phosphorylation of Hsp90alpha in a cAMP-dependent protein kinase A-dependent manner, and th
91 and shift in DNA organization act through a cAMP-dependent protein-kinase A-coupled signaling pathwa
92 disrupting hippocampal protein synthesis and cAMP-dependent-protein kinase A after the reactivation o
94 ophil apoptosis, as did inhibition of type I cAMP-dependent protein kinases activated downstream of P
96 of the G(alpha)s G-protein subunit and cAMP-cAMP-dependent protein kinase activation, the nitric oxi
98 renol-stimulated cAMP production (p = 0.04), cAMP-dependent protein kinase activity (p < 0.0004), pho
99 This result was consistent with attenuated cAMP-dependent protein kinase activity and reduced cyclo
100 stimulation of steroidogenesis by increasing cAMP-dependent protein kinase activity in both primary i
101 These agents were used to monitor endogenous cAMP-dependent protein kinase activity in erythrocyte ly
102 aracterize the compartmentalized location of cAMP-dependent protein kinase activity in mitochondria.
103 ndent protein kinase II activity, but not on cAMP-dependent protein kinase activity or presynaptic me
104 xemplifies two different ways for regulating cAMP-dependent protein kinase activity through non-conse
105 acting AKAP and suggest a mechanism by which cAMP-dependent protein kinase-AKAP binding can be modula
107 only demonstrate cross-talk between the cAMP/cAMP-dependent protein kinase and AMPK signaling modules
108 tic mutants in the phosphorylation sites for cAMP-dependent protein kinase and Ca(2)(+)/calmodulin-de
109 that Ca(V)1.1-S1575 is a substrate for both cAMP-dependent protein kinase and calcium/calmodulin-dep
110 effects are dependent on phosphorylation by cAMP-dependent protein kinase and cyclin-dependent prote
111 ly important neuromodulator uses synergistic cAMP-dependent protein kinase and endoplasmic reticulum
112 ypoglycemia, and catecholamine signaling via cAMP-dependent protein kinase and phosphorylation of inh
114 nus of NR2C, which is phosphorylated by both cAMP-dependent protein kinase and protein kinase C.
115 /dephosphorylation of serine 196 mediated by cAMP-dependent protein kinase and protein phosphatase.
116 l binding between the regulatory subunits of cAMP-dependent protein kinase and the anchoring domains
118 se activity and prevented phosphorylation by cAMP-dependent protein kinase at the neighboring Ser res
122 s and via activation of adenylyl cyclase and cAMP-dependent protein kinase, but some alternative down
123 a single phosphate to the activation loop of cAMP-dependent protein kinase by comparing the wild type
128 ites are highly conserved among AGC kinases (cAMP dependent Protein Kinase, cGMP dependent Protein Ki
130 so show that the regulation is via cAMP/PKA (cAMP-dependent protein kinase)-dependent signaling and p
136 atically potentiated following activation of cAMP-dependent protein kinase in DT40-3KO cells transien
138 drawal of 8-Br-cAMP and was inhibited by the cAMP-dependent protein kinase inhibitor H89 and the cyst
139 evels, as indicated by experiments using the cAMP-dependent protein kinase inhibitors H89 and PKI.
140 -3 induction by cAMP occurs independently of cAMP-dependent protein kinase, instead requiring the rec
142 iotic maturation by differentially impacting cAMP-dependent protein kinase, MAPK, NF-kappaB, and phos
143 glycoprotein inhibition was attributable to cAMP-dependent protein kinase-mediated inhibition of the
145 potentiation of the synaptic response via a cAMP-dependent protein kinase-mediated postsynaptic mech
147 hat mutation of the phosphorylation site for cAMP-dependent protein kinase on DARPP-32 attenuates l-D
148 ich of the two main cAMP sensors is at play: cAMP-dependent protein kinase or exchange protein direct
149 RI and RII) of the regulatory (R) subunit of cAMP-dependent protein kinase or protein kinase A (PKA)
150 y activation of the beta-adrenergic receptor/cAMP-dependent protein kinase pathway and up-regulation
151 s the clinical and molecular genetics of the cAMP-dependent protein kinase pathway in human pituitary
153 r713 phosphorylation through inhibition of a cAMP-dependent protein kinase/phosphatase-2A cascade.
155 g protein mAKAP serves as a scaffold for the cAMP-dependent protein kinase PKA and the cAMP-specific
159 control, the cyclic adenosine monophosphate (cAMP)-dependent protein kinase (PKA) holoenzyme typicall
160 gical state, cyclic adenosine monophosphate (cAMP)-dependent protein kinase (PKA) is a tetramer that
161 ) subunit of cyclic adenosine monophosphate (cAMP)-dependent protein kinase (PKA) is inhibited by two
164 prototypical cyclic adenosine monophosphate (cAMP)-dependent protein kinase (PKA-RIalpha), for which
166 ic mechanism of phosphorylation catalyzed by cAMP-dependent protein kinase (PKA) a structure of the e
167 receptors and intracellular cAMP binding to cAMP-dependent protein kinase (PKA) act together to indu
170 eases glucagon-stimulated cAMP accumulation, cAMP-dependent protein kinase (PKA) activity and downstr
171 tegrin function-blocking antibodies enhances cAMP-dependent protein kinase (PKA) activity and increas
173 udied the therapeutic potential of beta-cell cAMP-dependent protein kinase (PKA) activity in restorin
174 fusion transcript, which leads to increased cAMP-dependent protein kinase (PKA) activity in the inde
176 educed, but the increases in cAMP levels and cAMP-dependent protein kinase (PKA) activity were unaffe
177 gulation required receptor signaling via the cAMP-dependent protein kinase (PKA) and a specific PKA c
178 NOS and also abrogated epinephrine-dependent cAMP-dependent protein kinase (PKA) and Akt activation.
180 ex that controls the opposing actions of the cAMP-dependent protein kinase (PKA) and CaN in regulatio
183 e majority of cAMP functions are mediated by cAMP-dependent protein kinase (PKA) and exchange protein
184 family of proteins (AKAPs), which target the cAMP-dependent protein kinase (PKA) and other enzymes to
185 Previous reports have implicated type I cAMP-dependent protein kinase (PKA) and p90 ribosomal S6
186 found in dendritic spines that recruits the cAMP-dependent protein kinase (PKA) and protein phosphat
187 horing protein (AKAP)79/150 targets both the cAMP-dependent protein kinase (PKA) and protein phosphat
189 rotein directly activated by cAMP (EPAC) and cAMP-dependent protein kinase (PKA) are two intracellula
192 ion of the adenine ring selectively activate cAMP-dependent protein kinase (PKA) but not exchange pro
194 Previously, we described the inactivation of cAMP-dependent protein kinase (PKA) by direct oxidation
195 Subcellular compartmentalization of the cAMP-dependent protein kinase (PKA) by protein kinase A-
196 cal antagonism of NMDA receptors (NMDARs) or cAMP-dependent protein kinase (PKA) during post-MD sleep
197 trimeric G(s) protein, adenylyl cyclase, and cAMP-dependent protein kinase (PKA) for efficient signal
198 cellular model of memory storage, implicate cAMP-dependent protein kinase (PKA) in presynaptic and p
201 le is known about the regulation of cAMP and cAMP-dependent protein kinase (PKA) in these cells.
203 ve found that ET1 stimulates the activity of cAMP-dependent protein kinase (PKA) in VSMC as profoundl
204 ptors, phosphorylation of CaV1.2 channels by cAMP-dependent protein kinase (PKA) increases channel ac
211 yses of the cAMP binding domains of Epac and cAMP-dependent protein kinase (PKA) lead to a model of E
213 dramatically increased by activation of the cAMP-dependent protein kinase (PKA) pathway, which is im
217 r study has revealed age-related increase in cAMP-dependent protein kinase (PKA) phosphorylation of t
218 ked G protein-coupled receptor activation of cAMP-dependent protein kinase (PKA) plays an important r
219 isualise these two processes by studying the cAMP-dependent protein kinase (PKA) potentiation of pres
226 by FRET fluorescence ratio changes of tagged cAMP-dependent protein kinase (PKA) subunits expressed u
227 ases channel activity via phosphorylation by cAMP-dependent protein kinase (PKA) tethered to the dist
228 he well designed compartmentalization of the cAMP-dependent protein kinase (PKA) through its anchorin
229 A kinase anchor protein AKAP150 recruits the cAMP-dependent protein kinase (PKA) to dendritic spines.
230 kinase anchoring proteins (AKAPs) tether the cAMP-dependent protein kinase (PKA) to intracellular sit
231 inase anchoring proteins (AKAPs) that target cAMP-dependent protein kinase (PKA) to the channel.
232 damental cellular processes by directing the cAMP-dependent protein kinase (PKA) toward its intended
233 atio-temporal specificity for the omnipotent cAMP-dependent protein kinase (PKA) via high affinity in
235 ort, novel substrate-binding variants of the cAMP-dependent protein kinase (PKA) were used to identif
236 To determine the physiological role of the cAMP-dependent protein kinase (PKA), a mouse model was d
238 r mechanism of activation, dependence on the cAMP-dependent protein kinase (PKA), and the magnitude a
239 sensory neurons results in the activation of cAMP-dependent protein kinase (PKA), and this kinase pho
240 h the negative feedback loop formed by cAMP, cAMP-dependent protein kinase (PKA), and type 4 phosphod
241 the sites is predicted to be a substrate of cAMP-dependent protein kinase (PKA), and yeast expressin
242 inuing activity of adenylyl cyclase (AC) and cAMP-dependent protein kinase (PKA), as well as a scaffo
243 is a human anchoring protein that organizes cAMP-dependent protein kinase (PKA), Ca(2+)/calmodulin (
244 on of the c-fos gene conferred regulation by cAMP-dependent protein kinase (PKA), cGMP-dependent prot
245 kinetics of sites that are phosphorylated by cAMP-dependent protein kinase (PKA), even in highly homo
246 lated on threonine residue 35 (Thr35) by the cAMP-dependent protein kinase (PKA), inducing the potent
247 rements of global cAMP, general increases in cAMP-dependent protein kinase (PKA), or the activity of
250 nels is subject to pronounced enhancement by cAMP-dependent protein kinase (PKA), which is scaffolded
268 required NR2B-mediated downregulation of the cAMP-dependent protein kinase (PKA)/cAMP response elemen
269 ve small-molecule regulators for type Ialpha cAMP-dependent Protein kinase (PKA-Ialpha), a protein co
271 gnaling can regulate and be regulated by the cAMP-dependent protein kinase, PKA, although the molecul
272 t lead to an increase in the activity of the camp-dependent protein kinase, PKA, which triggers rapid
273 y, we reported that the catalytic subunit of cAMP-dependent protein kinase (PKAc) binds to the active
274 ondria the regulatory subunit RIalpha of the cAMP-dependent protein kinase (PKARIalpha); and the horm
279 a pathway that is sensitive to inhibitors of cAMP-dependent protein kinase [protein kinase A (PKA)].
280 al cells, serine/threonine kinases including cAMP-dependent protein kinase, protein kinase C and calm
281 and poor inhibition of other members of the cAMP-dependent protein kinase/protein kinase G/protein k
283 nding of RSPH3 to the regulatory subunits of cAMP-dependent protein kinase, RIIalpha and RIIbeta, is
284 volving mitogen-activated protein kinase and cAMP-dependent protein kinase signaling modules, wherein
285 ilar level in TG-RLC(P-) and NTG, suggesting cAMP-dependent protein kinase signaling to these protein
286 nuclear localization during fasting and cAMP/cAMP-dependent protein kinase signaling, suggesting loca
287 CRE-binding protein (CREB) or activation of cAMP-dependent protein kinase significantly increased GL
288 C5a orthologs efflux cyclic nucleotides, and cAMP-dependent protein kinase (Sp-CAPK/PKA) is expressed
289 hosphorylation of Synapsin I/II at serine 9 (cAMP-dependent protein kinase substrate site), serine 62
290 somatic mutations in PRKACA, which encodes a cAMP-dependent protein kinase that acts as a repressor p
291 Ps), defined by their capacity to target the cAMP-dependent protein kinase to distinct subcellular lo
292 activate mechanisms in addition to cAMP and cAMP-dependent protein kinase to modulate retinal gangli
293 ceptors (betaAR) in adipocytes activates the cAMP-dependent protein kinase to promote liberation of f
294 of cAMP, in parallel with the stimulation of cAMP-dependent protein kinase, to drive ribosomal protei
295 ssion of a non-coding transcript of PRKAR1A (cAMP-dependent protein kinase type I-alpha regulatory su
296 member 4 precursor, zinc finger protein 432, cAMP-dependent protein kinase type I-beta regulatory sub
297 rotein kinases (Pim-1, Pim-2, and Pim-3) and cAMP-dependent protein kinase were measured and found to
298 ptors that increase cAMP levels and activate cAMP-dependent protein kinase, which phosphorylates mamm
299 ccessfully applied to detect the activity of cAMP-dependent protein kinase with a low detection limit
300 surprising peptidergic transmission requires cAMP-dependent protein kinase, with only a minor contrib
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