ライフサイエンスコーパス: caerulein

1 lenged with seven more weeks of twice weekly caerulein.

2 B-mediated trypsinogen activation induced by caerulein.

3 after hyperstimulation with the CCK-8 analog caerulein.

4 r supramaximal secretagogue stimulation with caerulein.

5 but not when they are induced by exposure to caerulein.

6 d by 12 hourly intraperitoneal injections of caerulein.

7 ximally stimulating dose of the secretagogue caerulein.

8 supramaximally stimulating concentration of caerulein (10 nM).

9 se 5 weeks before induction of pancreatitis (caerulein, 50 mug/kg).

10 Caerulein administration to nontransgenic mice produced

11 ration of supraphysiologic concentrations of caerulein, an ortholog of cholecystokinin.

12 in Sprague-Dawley rats with a combination of caerulein and controlled intraductal infusion.

13 ol and fatty acids was between the extent of caerulein and L-arginine induction, with obvious inflamm

14 at HO-1 is induced in pancreatitis caused by caerulein and more prominently in severe pancreatitis ca

15 he effect of prior water immersion stress on caerulein and tumor necrosis factor-alpha (TNF-alpha)-in

16 administration of L-arginine (also in rats), caerulein, bile acid, or an AP-inducing diet.

17 lar effects to water immersion in preventing caerulein but not TNF-alpha-induced NF-kappaB activation

18 TG-AP by poloxamer 407 (P-407) combined with caerulein (Cae).

19 imal (10 microg/kg/h) dose of the CCK analog caerulein (CER).

20 NF-kappaB bioluminescence following 12 h of caerulein compared with baseline luminescence (p < 0.05)

21 ificantly lower in transgenic mice receiving caerulein compared with nontransgenic mice.

22 , in two groups of frog, an identical toxin, caerulein, has arisen repeatedly from unique genes in th

23 ntrations of cholecystokinin or its analogue caerulein have been shown to stimulate the proteolytic a

24 Further, pancreatitis outcomes using a mild caerulein hyperstimulation model were similar between IP

25 episodes of acute pancreatitis (AP) based on caerulein hyperstimulation.

26 rve, in real time, trypsinogen activation by caerulein in the pancreatic cancer cell line, MIA PaCa-2

27 Specifically, caerulein induced mild edematous pancreatitis accompanie

28 aches aimed at characterising the effects of caerulein-induced acute pancreatitis (AP) on the vagal n

29 duced by repeated episodes (twice weekly) of caerulein-induced AP (AP), we studied the involvement of

30 t hematopoietic cells were protected against caerulein-induced AP.

31 electron microscopy showed that BFA arrested caerulein-induced autophagosomal maturation.

32 In the caerulein-induced murine model of CP, administration of

33 Water immersion stress prevents supramaximal caerulein-induced NF-kappaB activation in pancreas in vi

34 of rats for up to 6 h prevents supramaximal caerulein-induced pancreatic IkappaB-alpha degradation a

35 The reduction in caerulein-induced pancreatic inflammation is dependent u

36 plasticity and pancreatic regeneration after caerulein-induced pancreatitis and in Kras(G12D)-driven

37 Prior stress ameliorates caerulein-induced pancreatitis in rats.

38 Similarly, hemin pretreatment in caerulein-induced pancreatitis reduces serum amylase and

39 ult mice, we compared regeneration following caerulein-induced pancreatitis to that of normal pancrea

40 t vasculature maintenance is observed during caerulein-induced pancreatitis.

41 y metaplasia, and persistent ADM after acute caerulein-induced pancreatitis.

42 ponsible for the effects of Tpl2 ablation on caerulein-induced proinflammatory events were evaluated

43 of agents that modulate intracellular pH on caerulein-induced trypsin and chymotrypsin activation we

44 Ex vivo, caerulein-induced trypsinogen activation is inhibited by

45 acinar cell injury in TLCS-induced, but not caerulein-induced, pancreatitis.

46 and trypsin activation were imaged in a rat caerulein-injection pancreatitis model.

47 We induced acute pancreatitis by repeated caerulein injections and isolated acinar and bone marrow

48 ethods, such as the peritoneal injections of caerulein, L-arginine, the retrograde infusion of sodium

49 The well-characterized caerulein model of CP was used to assess the therapeutic

50 dependently of trypsinogen activation in the caerulein model.

51 gonists of AhR in mice with AP (induced with caerulein or a choline-deficient diet supplemented with

52 hat were depleted of DCs and challenged with caerulein or L-arginine.

53 reatitis was induced in CD11c.DTR mice using caerulein or L-arginine; DCs were depleted by administra

54 st before induction of acute pancreatitis by caerulein or retrograde bile duct infusion of taurolitho

55 miR-21 deficiency protects against caerulein- or L-arginine-induced acute pancreatitis in m

56 matory transcription factor activated during caerulein pancreatitis.

57 Stimulation with either bethanechol or caerulein resulted in a rapid loss of fluorescence inten

58 e in [Ca(2+)](i) in response to supramaximal caerulein stimulation are reduced markedly in acini prep

59 Caerulein stimulation caused a time- and concentration-d

60 Acute pancreatitis was induced by caerulein stimulation in wild-type mice and mice deficie

61 Supramaximal caerulein stimulation induced subcellular redistribution

62 events when they are elicited, in vitro, by caerulein stimulation.

63 atitis induced by supramaximal secretagogue (caerulein) stimulation.

64 Concentrations of caerulein that induced ex vivo trypsinogen activation do

65 expression were characterized in control and caerulein-treated adult murine pancreas.

66 or adult and embryonic pancreatic markers in caerulein-treated and control pancreas, we addressed cel

67 rypsinogen activation peptide levels between caerulein-treated transgenic and nontransgenic mice.

68 In caerulein-treated transgenic mice, the histologic severi

69 Indeed, caerulein treatment increased processing of procathepsin

70 However, the cytoskeletal changes induced by caerulein were not affected by wortmannin.