ライフサイエンスコーパス: caffeic acid

1 e most abundant followed by verbascoside and caffeic acid.

2 hrough 4-coumaric acid and the other through caffeic acid.

3 ed the 3-hydroxylation of 4-coumaric acid to caffeic acid.

4 sts: trolox, ascorbic acid, gallic acid, and caffeic acid.

5 Both paths can be inhibited by caffeic acid.

6 s caffeoyl derivative and p-coumaric acid to caffeic acid.

7 e and caffeoyl aldehyde, and the lowest with caffeic acid.

8 oxyferuloyl CoA > 5-hydroxyconiferaldehyde > caffeic acid.

9 and UV spectroscopy and found to consist of caffeic acid.

10 , but SafBP does not O-methylate catechol or caffeic acid.

11 ection was observed with the 5-LO inhibitor, caffeic acid.

12 ugenol and isoeugenol as substrates, but not caffeic acid.

13 and lower affinity for 4-methylcatechol and caffeic acid.

14 t abundant was chlorogenic acid, followed by caffeic acid.

15 and phenolic compounds, such as tyrosine and caffeic acid.

16 as well as the multifunctional coumaric and caffeic acids.

17 ing the acidities of cinnamic, coumaric, and caffeic acids.

18 ss potent free radical scavengers gallic and caffeic acids.

19 red rices were catechin, protocatechuic and caffeic acids.

20 and mass spectral analyses and included five caffeic acid (1-5), three coumaric acid (6-8), and two c

21 21.9 degrees C) than those cross-linked with caffeic acid (229 g, 21.6 degrees C) and genipin (211 g,

22 merase (CHI), isoflavone reductase (IFR) and caffeic acid 3-0-methyltransferase (COMT) genes were als

23 enic alfalfa plants were generated harboring caffeic acid 3-O-methyltransferase (COMT) and caffeoyl C

24 Caffeic acid 3-O-methyltransferase (COMT) and caffeoyl C

25 amoyl transferase, ferulate 5-hydroxylase or caffeic acid 3-O-methyltransferase resulted in compositi

26 d functionally distinct lignin pathway OMTs, caffeic acid 3-O-methyltransferases (CAOMTs) and caffeoy

27 oside (2) together with four know compounds: caffeic acid (3), diosgenin beta-D-glucopyranoside (4),

28 nolic compounds were 7.80 (P. ostreatus) for caffeic acid, 4.55 (T. letestui) for chlorogenic acid, 1

29 ic acid (61+/-4microg/L/day; 6x>Control) and caffeic acid (41+/-4microg/L/day; 4x>Control).

30 ), protocatechuic acid (3), gallic acid (4), caffeic acid (5) and 3,4-dimethoxy cinnamic acid (6).

31 Caffeic acid/5-hydroxyferulic acid 3/5-O-methyltransfera

32 cytochrome P450-dependent monooxygenase, and caffeic acid/5-hydroxyferulic acid O-methyltransferase (

33 resence of native or recombinant Arabidopsis caffeic acid/5-hydroxyferulic acid O-methyltransferase a

34 anced by treatment with the natural products caffeic acid, 7,4-dihydroxyflavone and naringenin.

35 .03 mg/g), quercetrin (10.96 +/- 0.02 mg/g), caffeic acid (9.16 +/- 0.01 mg/g) and ellagic acid (9.03

36 +)-catechin, quercetin, gallic, ferulic, and caffeic acids) added to a model bread with regards to th

37 COMT inhibitors based on naturally occurring caffeic acid and caffeic acid phenethyl ester were devel

38 ) to release two different anticancer drugs (caffeic acid and chlorambucil, 1 equiv each).

39 zed and phenolic compounds found were mainly caffeic acid and danshensu and its derivatives, such as

40 and p-coumaric acids, seventeen polymers of caffeic acid and eight 3-O-glycosylated flavonols.

41 g the analysed phenols, only hydroxytyrosol, caffeic acid and ferulic acid always increased during fe

42 cids were cleaved and significant amounts of caffeic acid and ferulic acid were determined).

43 rutin (flavonoid), while polyphenolic acids (caffeic acid and gallic acid) although present in all wi

44 Phenolic compounds, especially caffeic acid and gallic acid, could lower lipid oxidatio

45 us honey); kaempferol, chrysin, pinocembrin, caffeic acid and naringenin (in rosemary honey) and myri

46 .e. Gallic acid, catechin, chlorogenic acid, caffeic acid and p-coumaric acid varied among species an

47 The ortho-diphenols were caffeic acid and phaselic acid, which were bound to bovi

48 ecoveries of 80-95%, except for gallic acid, caffeic acid and protocatechuic acid.

49 ce of mostly tannins and flavonoids, such as caffeic acid and quercetin.

50 hocarpa SDX; one converts p-coumaric acid to caffeic acid and the other converts p-coumaroyl shikimic

51 sented high concentration of procyanidin B1, caffeic acid and trans-resveratrol, with higher levels c

52 of some natural antioxidants (ferulic acid, caffeic acid and tyrosol) from chitosan-fish gelatin edi

53 s/trans-aconitic acids, between aconitic and caffeic acids and between quercetin-3-O-galactoside and

54 o different families: flavonoids; quinic and caffeic acids and derivatives; diterpenoids (including s

55 phenols, 2,2,5,7,8-pentamethylchroman-6-ol, caffeic acid, and (+)-cathechin) to a series of N-oxyl r

56 nown antitrypanosomal phenolics gallic acid, caffeic acid, and chlorogenic acid.

57 ined significant amounts rutin, gallic acid, caffeic acid, and chlorogenic acid.

58 ar weight phenylpropanoids, such as eugenol, caffeic acid, and rosmarinic acid, that result from meta

59 convert virtually all added ferulic acid to caffeic acid, and that VirH2 is essential for this O-dem

60 mug GAE mg(-1)), while minor compounds were caffeic acid, apigenin, hesperetin and naringenin.

61 s for the COOH and OH groups of coumaric and caffeic acids are 332.7 +/- 2.0, 318.7 +/- 2.1, 332.2 +/

62 Lower content of sugars, coumaric and caffeic acids, as well as higher amount of gamma-aminobu

63 Furthermore, p-coumaric and caffeic acids, as well as procyanidin dimer B, were extr

64 agents, namely, genipin, glutaraldehyde and caffeic acid, at different concentrations.

65 oxycinnamoyl derivatives mostly derived from caffeic acid, being 3-O-caffeoylquinic acid and rosmarin

66 Accumulation of soluble caffeic acid beta-d-glucoside occurred only in CCOMT dow

67 arming significantly increased the levels of caffeic acid by 20%, but reduced those of ferulic acid a

68 id (p-CA) derivatives, FA derivatives, p-CA, caffeic acid (CA) and CA derivatives.

69 th that exerted by their unsaturated analogs-caffeic acid (CA) and ferulic acid (FA).

70 trode was developed for the determination of caffeic acid (CA) in wine.

71 aviour and the quantitative determination of caffeic acid (CA) on a disposable pencil graphite electr

72 ntly coupling beta-Lactoglobulin (betaLg) to caffeic acid (CA) using crosslinker chemistry at differe

73 piperita (ExMp), and the phenolic compounds caffeic acid (CA), rosmarinic acid (RA), lithospermic ac

74 In particular, the caffeic acid (CA)-bearing zanamivir (ZA) conjugates ZA-7

75 A reaction between caffeic acid, CA, and its specially synthesised C1-C16 a

76 a new, green, and efficient reducing agent (caffeic acid/CA) for GO reduction.

77 ifferent food constituents (l-ascorbic acid, caffeic acid, caffeine, curcumin, (-)-epigallocatechin g

78 The diphenolic moiety of caffeic acid can be polymerized by biocatalysis with lac

79 s from pulp and peel, whereas seed displayed caffeic acid, catechin and epicatechin as its main pheno

80 aluated and its major phenolic constituents, caffeic acid, chlorogenic acid and 3,5 dicaffeoylquinic

81 project, quercetin, catechin, ascorbic acid, caffeic acid, chlorogenic acid and acetylcysteine were s

82 Some antioxidant levels (cis-caffeic acid, chlorogenic acid, 3,4-dihydroxycinnamic ac

83 -diphenols such as catechol, methylcatechol, caffeic acid, chlorogenic acid, and phaselic acid show d

84 The highest level of caffeic acid content was found in the R. dumalis ranged

85 Rosmarinic acid (RA) and caffeic acid contents significantly enhanced after the a

86 Our results suggest that Ptr4CL5 and caffeic acid coordinately modulate the CoA ligation flux

87 r main phenolic compounds: chlorogenic acid, caffeic acid, coumaric acid and protocatechuic acid, as

88 , phenolic compounds, catechin, epicatechin, caffeic acid, coumaric acid, acetaldehyde, total and red

89 n phenolics allowed the identification of 12 caffeic acid derivatives and related phenolics, 10 rosma

90 These results identify selected caffeic acid derivatives as novel K+ channel openers tha

91 The activation of bTREK-1 by caffeic acid derivatives did not occur through inhibitio

92 ulata cells, it was discovered that selected caffeic acid derivatives dramatically enhanced the activ

93 the predominance of anthocyanins in fruits, caffeic acid derivatives in leaves whereas flavanol olig

94 Furthermore, several isomers of caffeic acid derivatives were distinguished for the firs

95 s at high CO2 concentrations while only some caffeic acid derivatives were increased, and not uniform

96 xtracts gave 4 fractions, with fraction F-I (caffeic acid derivatives) showing a strong activity agai

97 led to mass spectrometric detection, several caffeic acid derivatives, 5-feruloylquinic and 5-p-couma

98 indicate that COMT is unlikely to methylate caffeic acid during lignin biosynthesis in vivo, and pro

99 ikely to catalyze the in vivo methylation of caffeic acid during lignin biosynthesis.

100 g a very good correlation for vanillic acid, caffeic acid, epicatechin and resveratrol.

101 by DPV on PGE were 35.81, 34.59 and 31.21 mg caffeic acid equivalent/g tea, respectively.

102 r high in phenolics (18 compared with 286 mg caffeic acid equivalents per kg, respectively) for 6 wk.

103 ied between 76 and 108mgCAEg(-1) of extract (caffeic acid equivalents) and 39 and 54mgQEg(-1) of extr

104 rete rosmarinic acid (RA), a multifunctional caffeic acid ester that exhibits in vitro antibacterial

105 In both emulsion systems, caffeic acid esterified with fatty alcohols of different

106 For the first time, caffeic acid esters of isocitric and several aldaric aci

107 TREK-1 channels were also activated by other caffeic acid esters, including caffeic acid phenethyl es

108 in P. patens caused accumulation of Phe and caffeic acid esters.

109 -flavonoid phenolic acids (chlorogenic acid, caffeic acid, ferulic acid) and a flavonoid (rutin) to i

110 o the coffee polyphenols family, four acids (caffeic acid, ferulic acid, 5-O-caffeoyl quinic acid, an

111 Phenolic acids (e.g. rosmarinic and caffeic acids), flavones (e.g. luteolin derivatives) and

112 ioxidative activities of phenolic compounds (caffeic acid, gallic acid and tannic acid; 200 ppm) in w

113 , for the analysis of epicatechin, catechin, caffeic acid, gallic acid, and vanillic acid; and excita

114 techin, epicatechin, quercetin, resveratrol, caffeic acid, gallic acid, p-coumaric acid, and vanillic

115 >8)-epicatechin dimer (procyanidin B2), VIII.caffeic acid glycoside, XIX.epicatechin-(4beta-->8)-epic

116 The compounds comprised caffeic acid glycosides, simple phenolics (protocatechui

117 d and caffeoyl alcohol > caffeoyl aldehyde > caffeic acid > 5-hydroxyconiferaldehyde.

118 PAs bound to different relative extents with caffeic acid>chlorogenic acid>ferulic acid.

119 ified elevated levels of p-coumaroyl hexose, caffeic acid hexoside and ferulic acid hexoside in CCR-R

120 essed products allowed the quantification of caffeic acid hexosides, which are far more important con

121 and its six colonic catecholic metabolites (caffeic acid, hydrocaffeic acid, homoprotocatechuic acid

122 sociation enthalpies for these compounds and caffeic acid in benzene, methanol, and water were used f

123 rutin in skin of Ghara Shira (298 mug/g) and caffeic acid in cane of Ghara Shira (17.4 mug/g).

124 Caffeic acid in the free and glycoside forms and syringi

125 selected phenolic compounds (rosmarinic and caffeic acid) in the oil.

126 Feeding cv Mitchell flowers with caffeic acid induced PHZ expression, suggesting that the

127 ydroxycinnamic acids, such as 4-coumaric and caffeic acids, into hydroxycinnamoyl-CoA thioesters.

128 erulic acid remained unchanged, whereas with caffeic acid it was significantly inhibited.

129 ively, 3-hydroxylation of 4-coumaric acid to caffeic acid may occur through an enzyme complex of cinn

130 The Ptr4CL5-catalyzed caffeic acid metabolism, therefore, may also act to miti

131 feoyltartaric acid was shown to be the major caffeic acid metabolite in leaves.

132 led rapid access to the structurally related caffeic acid metabolite rufescenolide through an unexpec

133 ty but composed exclusively by the quinic or caffeic acid moiety of CQAs.

134 cis-elements present in the promoter of the caffeic acid O-methyl transferase (comt) gene.

135 a simultaneous reduction in both CCoAOMT and caffeic acid O-methyltransferase (CAOMT).

136 to express ferulate 5-hydroxylase (F5H) and caffeic acid O-methyltransferase (COMT) from Liquidambar

137 Caffeic acid O-methyltransferase (COMT) is a bifunctiona

138 The enzyme caffeic acid O-methyltransferase (COMT) is central to li

139 In contrast, downregulation of caffeic acid O-methyltransferase (COMT) reduced activiti

140 We found that caffeic acid O-methyltransferase (COMT1) is a common tar

141 tase1 [CCR1], ferulate 5-hydroxylase [F5H1], caffeic acid O-methyltransferase [COMT], and cinnamyl al

142 g S-adenosyl-methionine as the methyl donor, caffeic acid O-methyltransferase from sorghum (Sorghum b

143 Down-regulation of the switchgrass caffeic acid O-methyltransferase gene decreases lignin c

144 in plastid development), and brown midrib3 (caffeic acid O-methyltransferase), were silenced and cha

145 biosynthesis of lignin cell wall precursors (caffeic acid O-methyltransferase).

146 eyl aldehyde which then is 3-O-methylated by caffeic acid O-methyltransferase.

147 hydroxylase in a line of Arabidopsis lacking caffeic acid O-methyltransferase.

148 avone reductase, cinnamoyl-CoA reductase and caffeic acid O-methyltransferase.

149 have 70% identity to S-adenosyl-L-methionine:caffeic acid O-methyltransferase.

150 e analysis these enzymes are most similar to caffeic acid O-methyltransferases (COMTs), but they have

151 protein sequence shared homology with plant caffeic acid O-methyltransferases and related enzymes.

152 he greatest increases in chlorogenic (152%), caffeic acid-O-glucoside (170%) and caffeic (140%) acids

153 eer for the first time: feruloylquinic acid, caffeic acid-O-hexoside, coumaric acid-O-hexoside, sinap

154 In addition to being caffeic acid oligomers, yunnaneic acids A and B are form

155 Two clusters of genes coding for caffeic acid OMT (COMT) have been identified in the appl

156 ale surface patterning and polymerization of caffeic acid on 4-aminothiophenol-functionalized gold su

157 anine or methionine) and either gallic acid, caffeic acid or (+)-catechin ortho-quinones were evaluat

158 Films containing caffeic acid or a caffeic-ferulic acid mixture exhibited

159 Wine-model solutions with gallic acid, caffeic acid, or (+)-catechin and nucleophilic compounds

160 ccase biosensor has responded efficiently to caffeic acid over a concentration range of 0.38-100micro

161 and hydroxycinnamic acids (rosmarinic acid, caffeic acid, p-coumaric acid).

162 beta-d-glucopyranosyl sinapate (5.6%), while caffeic acid, p-coumaric acid, hesperidin and naringenin

163 gallate, procyanidin B1, rutin, gallic acid, caffeic acid, p-coumaric acid, pelargonidin-3-glucoside,

164 ther with already known phenolics, including caffeic acid, p-coumaric acid, rutin, scopoletin, N-tran

165 ies, whereas Ptr4CL5 regulates primarily the caffeic acid path.

166 tudy, the combined effect of sulfur dioxide, caffeic acid, pH and temperature on the light-induced (3

167 We found that the natural product caffeic acid phenethyl ester (CAPE) disrupts neural cres

168 Caffeic acid phenethyl ester (CAPE) is a phenolic antiox

169 We investigated the mechanisms by which caffeic acid phenethyl ester (CAPE), a phenolic antioxid

170 iciency virus type 1 (HIV-1) integrase (IN); caffeic acid phenethyl ester (CAPE), a putative three-po

171 Caffeic acid phenethyl ester (CAPE), a specific inhibito

172 Here we show that caffeic acid phenethyl ester (CAPE), an active component

173 Caffeic acid phenethyl ester (CAPE), an active component

174 In the present study, we found that caffeic acid phenethyl ester (CAPE), known to inhibit NF

175 itor U0126; NF-kappaB inhibitors BAY11-7085, caffeic acid phenethyl ester (CAPE), parthenolide, and c

176 olic moieties in compounds such as flavones, caffeic acid phenethyl ester (CAPE), tyrphostins, and cu

177 ated by other caffeic acid esters, including caffeic acid phenethyl ester (CAPE), which contain a ben

178 r examined by use of an NF-kappaB inhibitor, caffeic acid phenethyl ester (CAPE).

179 rrolidinedithiocarbamate (PDTC; 100 microM), caffeic acid phenethyl ester (CAPE; 90 microM), and MG-1

180 B) was also demonstrated using the inhibitor caffeic acid phenethyl ester and electrophoretic mobilit

181 aB activation by the pretreatment of DC with caffeic acid phenethyl ester blocks L. major-induced IRF

182 n propolis samples, which was assigned to be caffeic acid phenethyl ester by mass spectrometry.

183 ha or treatment with the NF-kappaB inhibitor caffeic acid phenethyl ester greatly diminishes the indu

184 with the NF-kappaB inhibitors BAY117085 and caffeic acid phenethyl ester led to a concentration-depe

185 ased on naturally occurring caffeic acid and caffeic acid phenethyl ester were developed.

186 rphine activated NF-kappaB promoter and that caffeic acid phenethyl ester, a specific inhibitor of th

187 ence of dicaffeoylquinic acid, ellagic acid, caffeic acid phenethyl ester, and chlorogenic acid, amon

188 paB pathway, namely SC-514, BAY 11-7082, and caffeic acid phenethyl ester, attenuated NO, TNF-alpha,

189 r pp2, the nuclear factor- kappa B inhibitor caffeic acid phenethyl ester, EGFR neutralizing antibodi

190 Total furan formation was inhibited by caffeic acid, punicalagin, epicatechin, ECE and PPE duri

191 y was significantly (P<0.05) correlated with caffeic acid (R(2)=0.8309) and total HA (R(2)=0.3942) co

192 Berry juice, green tea, red wine, and caffeic acid reduced oxygen uptake in the acidic environ

193 limits were 8.83x10(-8) M and 2.94x10(-7) M caffeic acid, respectively.

194 However, heating of a CGA moiety, caffeic acid, resulted in high yield of CO2 (>98%), sugg

195 PGF(2 alpha) can be chemically inhibited by caffeic acid, resveratrol and nordihydroguaiaretic acid.

196 of iron as well as the natural antioxidants caffeic acid, rosemary extract, and ascorbic acid result

197 but could not prevent its production, while caffeic acid showed no significant impact.

198 lem caused inhibition of 4CL activity toward caffeic acid similar to that under compressional stress.

199 that the ref8 mutant is unable to synthesize caffeic acid, suggesting that the mutant is defective in

200 mulated-digestion-released phenolics (mainly caffeic acid, syringic acid and vanillic acid) from brea

201 and B) and trimeric (C and D) assemblies of caffeic acid that feature an array of synthetically chal

202 In potato tuber, caffeic acid (the predominant hydroxycinnamic acid (HCA)

203 were compared with those for chlorogenic and caffeic acids (the main hydroxycinnamic acids of plant m

204 s showed: 1) An optimal molar ratio (8:1) of caffeic acid to betaLg was obtained at pH 6; 2) DPPH act

205 on of 4-coumaric acid to 4-coumaroyl-CoA and caffeic acid to caffeoyl-CoA.

206 , may also act to mitigate the inhibition by caffeic acid to maintain a proper ligation flux.

207 Ferulic acid was far more toxic than caffeic acid to the wild-type strain, although the wild-

208 t or with phenolic compounds (vanillic acid, caffeic acid, trans-cinnamic acid, 2,4-dihydroxycinnamic

209 c acid, p-coumaric acid, trans-ferulic acid, caffeic acid, trans-resveratrol, (+)-catechin and (-)-ep

210 n with antioxidants (vitamin C, gallic acid, caffeic acid, trolox), synergy or additivity effects wer

211 However, the conversions of ferulic and caffeic acids under the same conditions were much lower

212 main compounds were hydroxytyrosol, tyrosol, caffeic acid, vanillic acid, verbascoside, oleuropein, f

213 rulic acid, chlorogenic acid, vanillic acid, caffeic acid, vanillin, ortho- and para-coumaric acids,

214 The antioxidative effect of lipophilized caffeic acid was assessed in two different fish oil enri

215 A high level of caffeic acid was detected in stem-differentiating xylem

216 during the duodenal digestion whereas 88% of caffeic acid was released in the colon step.

217 Caffeic acid was slowly removed from the broth, suggesti

218 ounds 22-27) based on a dietary antioxidant (caffeic acid) was performed.

219 ntains polyphenols including gallic acid and caffeic acid, was evaluated.

220 in precursors, including p-coumaric acid and caffeic acid, we found strong associations (P values to

221 Moreover, dimers, trimers and tetramers of caffeic acid were identified and quantified for the firs

222 chin, (-)-epigallocatechin, tannic acid, and caffeic acid were selected as model antioxidants to stud

223 onditions induced degradation of ferulic and caffeic acids, whereas the amount of sinapic acid increa

224 effective concentration' for epicatechin and caffeic acid, whilst addition of caffeoylquinic acids re

225 Chlorogenic acid (CQA), the ester of caffeic acid with quinic acid supplied to human organism

226 Chlorogenic acid, the ester of caffeic acid with quinic acid, is one of the most abunda