ライフサイエンスコーパス: cage

1 d Ex moves upward, out of the positive helix cage.

2 rst example of a triple cavity [Pd4(L)4](8+) cage.

3 gy states have two anions bound in the helix cage.

4 bled to build a highly symmetric icosahedral cage.

5 reaction was observed in the absence of the cage.

6 the anchoring of the cluster to the protein cage.

7 controlled activity, as well as in the home cage.

8 for key C-H hydroxylation within the solvent cage.

9 nthetic biologists to design de novo protein cages.

10 into europium (Eu) tetrametallic tetrahedral cages.

11 egy of selective elongation of metal-organic cages.

12 all-pore zeolite SSZ-39 with the OSDA in its cages.

13 ully attenuated when bound within one of the cages.

14 -185a due to selective elongation of tubular cages.

15 alization contrasts with previously reported cages.

16 nalized heteroleptic cis-[Pd2(La)2(Lb)2](4+) cages.

17 ape-persistence on the porosity of molecular cages.

18 en lung tissue from sibling rats of the same cages.

19 n in virus particles and other large protein cages.

20 with a smaller magnitude because of solvent caging.

21 BF render it superior to Bhc for thiol group caging.

22 e demonstrate that an Fe(II)4L4 coordination cage 1 can transport a cargo spontaneously and quantitat

23 exchange transformed new high-spin Fe(II)4L4 cage 1 into previously-reported low-spin Fe(II)4L4 cage

24 Fe(II)4L6 tetrahedral cage 1 undergoes post-assembly modification (PAM) via a

25 into previously-reported low-spin Fe(II)4L4 cage 2: 2-formyl-6-methylpyridine was ejected in favor o

26 were characterized by NMR and HRMS, and for cage 3 incorporating 1,4-diazabicyclo[2.2.2]octane (DABC

27 1 and previously-reported low-spin Fe(II)4L6 cage 3 resulted in the destruction of 1 and the release

28 The synthesis of two flexible bis-porphyrin cages 3 and 4, incorporating respectively Zn(II) porphyr

29 Caging a fluorophore with this ion-sensitive moiety yiel

30 Enantiopure alleno-acetylenic cage (AAC) receptors with a resorcin[4]arene scaffold, f

31 lofullerene with three Gd ions in one carbon cage, acts as a satellite anchoring on the surface of PD

32 A cages, where polymer length determines the cage aggregation number.

33 The Fe(II)8L6 cage also enabled the reaction of C60 and anthracene to

34 ification of dozens of protein biomarkers in caged amphipods (Gammarus fossarum).

35 Based on CAGE and Pol II localization data, we found strong evide

36 rum half-life of the amphiphile bound to the cage and the protein was shown to reach up to 22 hours,

37 to the rotation of NH4(+) within its solvent cage and then to the symmetry of hydrogen bonds.

38 the loss of the V27 pocket for the adamantyl cage and to a predominant orientation of the ligand's am

39 rons while they were freely moving in a home cage and while they performed a PFC-dependent task that

40 s among unexplored inorganic crystals beyond caged and layered structures.

41 n, capable of extracting metal ions in their cages and a consequence of the electron transfer of meta

42 ligand edge exchange reaction in one of the cages and for the unusual activation parameters in the h

43 nctive pore topology with large heart-shaped cages and framework flexibility.

44 elease survival and response to MAT in field cages and in a commercial orchard.

45 ptured in MAT baited traps in both the field cages and orchard trials compared to RK denied sterile m

46 lite, the archetype of molecular sieves with cages and the most widely used as a catalyst and sorbent

47 The photophysical properties of these cages and their fullerene-encapsulated adducts were stud

48 cationic cages to separate a mixture of two cages and their respective cargoes.

49 hippocampus compared with rats from control cages and those from stable hierarchies.

50 be achieved with counterionic macromolecular caging and decaging at the nanoscale.

51 entrality and hubness parameters in the home-caged animals.

52 )3] and [N(CH3)4]4[Br4(XeO3)4], in which the cage anions have Xe-Br bond lengths that range from 3.08

53 They are the only known examples of cage anions that contain a noble-gas element.

54 r 6 months of housing in standard laboratory cages, APPSWE /PS1dE9 (n = 27) and healthy wildtype (n =

55 how negative thermal expansion when internal cages are empty but positive thermal expansion when addi

56 The cages are highly emissive (luminescence quantum yields o

57 metal-rare-earth heterometallic coordination cages are reported, abbreviated as {Ni64 RE96 } (RE=Gd,

58 o BODIPY chromophores along the edges of the cages, arising from the electronic delocalization throug

59 o infected mosquitoes in the standard arm-in-cage assay.

60 ely to a 30% dose in the conventional arm-in-cage assays.

61 Three Zn(II)4L4 coordination cages, assembled from trisiminopyridine ligands, exhibit

62 insically or extrinsically to decane solvent cage assemblies.

63 rent exo and endo functionalities within the cage assembly were generated, suggesting that this metho

64 icavity [Pdn(L)4](2n+) metallosupramolecular cages based on long backboned ligands are an attractive

65 lation reduces the immunogenicity of protein cage-based delivery systems and active targeting ligands

66 This cage bound C60-indene or C60-anthracene bisadducts selec

67 A novel supramolecular cage built from the self-assembly of tris(2-pyridylmethy

68 ated diffusion, where DNA confines LacI in a cage, but LacI can move between cages when hindering DNA

69 erase into a well-defined octahedral protein cage by appending a C4-symmetric coiled-coil domain to t

70 the electron transfer of metal ions in their cage by reduction and oxidation processes, electrochemic

71 In all three isomers, one cage C atom occupies a degree-4 vertex on the short para

72 mately leading to the closed-shell fullerene cage C60(-) as preprogrammed by the precursor structure.

73 esign, synthesize and optimize a DNA-minimal cage capable of encapsulating oligonucleotide drugs to f

74 Prepared caged carbons could regain their emission only through i

75 S release kinetics from a series of isomeric caged-carbonyl sulfide (COS) compounds, including thioca

76 t synthetic non-endogenous agents within the cage cavity and deliver them to targeted tissue cells wi

77 Two shape-persistent covalent cages (CC1(r) and CC2(r)) have been devised from triphen

78 ss works to its advantage in stabilizing the cage; chloride, bromide, and iodide do not bring about s

79 basal quality control autophagy and vimentin cage clearance in CCHE-45 are mediated by MAP1LC3A.

80 logy and find a novel spatial correlation of CAGE clusters with donor splice sites and with poly(A) s

81 properties of a new class of hemicryptophane cages combining a cyclotriveratrylene unit and a tris(2-

82 hole substrate, or the substrate pieces in a caged complex.

83 aeolicus (AaLS) and found that it also forms cage complexes with the cognate riboflavin synthase (AaR

84 are a venerable class of macrocyclic and/or cage compounds that often feature high strain, unusual c

85 rward and efficient, providing gram-scale of cage compounds.

86 Such cloaked caged compounds will enable the study of the signaling o

87 To test this hypothesis without using caged compounds, force responses and individual sarcomer

88 ents and the loading with indicator dyes and caged compounds.

89 syntheses of oxime-based metal complexes and cage-compounds, oxime functionalizations, and the prepar

90 luated before and after exercise training or cage confinement.

91 which are 'moulded' on the inside of the DNA cage, consist of a monodisperse crosslinked polymer core

92 ctive synthesis of a chiral covalent organic cage consisting of three redox-active naphthalene-1,4:5,

93 vidual Ar atoms are trapped at 300 K in nano-cages consisting of (alumino)silicate hexagonal prisms f

94 mbled dimers of interpenetrated coordination cages consisting of redoxactive chromophors were synthes

95 ve prepared a series of M(II)4L6 tetrahedral cages containing one or the other of two distinct BODIPY

96 es of the scope of this method revealed that cages containing tetratopic and tritopic ligands were mo

97 ching with NH4F, is also applicable to other cage-containing microporous molecular sieves, where some

98 were exposed to the social stressor or home cage control conditions for six consecutive days and all

99 exercise training or remained as sedentary, cage-controls.

100 ophilic sulfate; the resulting water-soluble cages could be rendered water-insoluble through reverse

101 nd-forming step, which occurs through out-of-cage coupling of an alkyl radical.

102 he crystallinity, preferred orientation, and cage crystal growth was obtained by experimental and com

103 two-dimensional (2D) oriented porous organic cage crystals (consisting of imine-based tetrahedral mol

104 with matching Cap Analysis Gene Expression (CAGE) data, from 396 human and 47 mouse RNA samples.

105 ing FANTOM5 cap analysis of gene expression (CAGE) data, we integrate multiple transcript collections

106 region where the formation of double-diamond cages (DDCs) is favored in comparison with the bulk.

107 oping, the present result indicates that the cage defined by the cations plays critical roles in carr

108 d leads to the failure of aggresome vimentin cage degradation.

109 ng from the Cap Analysis of Gene Expression (CAGE) demonstrate that promoters and enhancers, based on

110 rus-like particles (VLPs) are stable protein cages derived from virus coats.

111 xis as a result of oversized cube-octahedral cages determined by the larger K ions.

112 This cage differs in that the central cavity is phenyl-linked

113 onstrate that the microporosity of molecular cages directly correlates with shape persistence.

114 ce of large voids (solvent vapor bubbles) in cages dissolved in nitromethane.

115 Moreover, the conformational changes of DNA cages drive membrane fusion and bending with predictable

116 esting that biotic interactions (absent from cages) drive ecological limits at warmer margins.

117 ition of an excess of acid fully expands the cages due to electrostatic repulsion between the positiv

118 Age-matched, cage-dwelling, Veh- and Tam-treated mice without wheel a

119 sulated in amounts of up to one molecule per cage, equivalent to a concentration of 0.175 m, which is

120 All cages exhibited the same progression from an initial bri

121 Population modeling and cage experiments indicate that a CRISPR-Cas9 construct t

122 We set up laboratory population cage experiments to evaluate the outcome of the interact

123 By contrast, cage fitness (productivity) increased towards warmer, lo

124 investigate the self-assembly of a spherical cage, focusing on the regularity of the packing of prote

125 structure with its characteristic tryptophan-cage fold motif that is responsible for favorable chemic

126 l that these CCHs share a conserved aromatic cage for the hydrolytic activity.

127 Fathead minnows were deployed in cages for 2, 4, or 8 days at three locations near two di

128 are still large and require relatively large cages for housing.

129 g and palatable food; 20 trials/day) or home-cage forced abstinence.

130 ion of palladium salts in the absence of the cages form structure less agglomerates.

131 Upon cage formation, the charge-transfer character exhibited

132 otease resistance provided by the protective cage formed by the MOF around the encapsulated enzymes.

133 d geometries may be used as templates in the cage forming reactions.

134 The cage-forming enzyme lumazine synthase (LS) from Bacillus

135 h Fe(II) or Zn(II) gave a new cubic M(II)8L6 cage framework with electron-deficient walls.

136 olecular CHpi interactions within all of the cage frameworks play an important role in abetting the c

137 The formation of quasi-spherical cages from protein building blocks is a remarkable self-

138 njugation of a large, neutral dendrimer to a caged GABA probe we introduce a "cloaking" technology th

139 o exploiting these new coumarin scaffolds as caging groups that can be removed with visible light.

140 Three tetrahedral organic cages have been obtained by condensing a triamino linker

141 rous solids fabricated from discrete organic cages have garnered much interest due to their ease of h

142 Ferritin is an iron cage having protein, capable of extracting metal ions in

143 ) salts, we were able to prepare O-symmetric cages having a confined volume of ca. 1300 A(3) .

144 at bristles with ethyl groups mounted onto a caged heterotricyclic core.

145 f fullerene, the iconic Buckminsterfullerene cage, I h-C60, is entirely avoided in the bottom-up form

146 Unlike the caging imposed by an inert matrix, an active lattice par

147 he fact that the isomeric form of the carbon cage in endohedral metallofullerenes (EMFs) often differ

148 ion occupies the center of the sodalite beta-cage in Na8[AlSiO4]6(ReO4)2.

149 rements indicate the stability of the cubane cage in solution.

150 lymeric nanoparticle encapsulated inside the cage in three dimensions.

151 are provided to enable the design of protein cages in any polyhedral shape.

152 In three of four cages in each treatment, ES dominated the interaction.

153 segments likely direct RS complexation by LS cages in other bacterial species.

154 e use of iron(II) salts yielded coordination cages in the high-spin state at room temperature, manife

155 d and characterized >20 single-chain protein cages in three shapes-tetrahedron, four-sided pyramid, a

156 uding solids with high band degeneracy, with cages in which atoms rattle, with nanostructures at vari

157 d the disruption of the aggresomes' vimentin cage independent of MAP1LC3B positive autophagosomes.

158 agonist CL 316, 243 and underwent metabolic cage, infrared thermal imaging and (18)F-FDG PET/MRI exp

159 Geometrical frustration of the molecule-cage interaction in FAPbI3 produces a disordered gamma-p

160 The effects of structural motifs and cluster-cage interactions on formation of compounds in the solve

161 Construction of a 3D organic cage introduces a new piece to the system by swapping th

162 isphosphate (IP3) receptors by photolysis of caged IP3 The rate of Ca(2+) removal from the cytosol wa

163 receptors stimulated with IP3 released from caged-IP3 .

164 This new water-soluble cage is flexible and able to encapsulate anions with vol

165 This cubic cage is flexible and compatible with aqueous media.

166 The conversion of doped graphite into a C80 cage is shown to occur through bottom-up self-assembly r

167 specific enzymes in self-assembling protein cages is a hallmark of bacterial compartments that funct

168 The two cage isomers can coexist in solution and interconvert.

169 n of hydrophobic polymers on one face of the cage leads to hydrophobically driven formation of quanti

170 ls in a total of 1,829 human and 1,029 mouse CAGE libraries.

171 of vimentin filaments, which sometimes had a cage-like appearance, occurred in sacsin-deficient cells

172 that are associated with dysregulated septin cage-like formation, impaired autophagic p62/LC3 recruit

173 stage aldol reaction to furnish the complex cage-like framework.

174 e prediction of the active site revealed its cage-like function that opens for ligand entry and then

175 50- to 80-nm membrane invaginations lined by cage-like polygonal structures [7, 8] formed by caveolin

176 o aggregated perinuclear tubules that form a cage-like structure around the nucleus.

177 Moreover, cage-like structures were patterned within the scaffolds

178 t hydrogen bonding leads to open tetrahedral cage-like structuring that contributes to its remarkable

179 In the case of cages loaded with C60 or C70 fullerenes, ultrafast host-

180 , and in vivo imaging applications of Copper-Caged Luciferin-1 (CCL-1), a bioluminescent reporter for

181 t the synthesis and characterization of iron-caged luciferin-1 (ICL-1), a bioluminescent probe that e

182 ism that underlie formation of unique carbon cage materials, which may be used as a benchmark to guid

183 eassortants also infected and transmitted to cage mates.

184 olonized mice and efficiently transmitted to cage-mates, the mutant colonized less efficiently, shed

185 (i) many designed, or even natural, protein cages may not be regular in the presence of those pertur

186 adicals is catalyzed by copper via an out-of-cage mechanism in which [Cu(I)(carb)2](-) and [Cu(II)(ca

187 t as a new class of ligands for coordination cages, metal-organic frameworks, and small-molecule tran

188 s, crystalline solids such as porous organic cages, metal-organic polyhedra, covalent organic framewo

189 ofiles corresponding to the unfolding of Trp-cage miniprotein in the presence and absence of urea at

190 subcutaneously in rats by using a validated cage model, allowing for free fluid and cellular exchang

191 selectively depolarizing the xenon within a cage molecule which, upon exchange, reduces the signal i

192 The caged molecule is stable and releases InsP7 only on irra

193 Porous organic cage molecules are fabricated into thin films and molecu

194 del from perovskite intermediated [PbI6](4-) cage nanoparticles to bulk polycrystals is proposed to u

195 Caged neurotransmitters, in combination with focused lig

196 association of two [I-H](+) cations within a cage of [BPh4](-) anions.

197 psulation of enzymes within a single protein cage of cowpea chlorotic mottle virus (CCMV) at neutral

198 To achieve this, DNA cages of different geometries are combined with sequence

199 edicted cubic metallic phase of LaH10 having cages of thirty-two hydrogen atoms surrounding each La a

200 The three cages of this study exhibit high thermodynamic and kinet

201 an easy access to the enantiopure molecular cages of which absolute configurations have been assigne

202 n the UV to visible spectral regions through caging of a variety of dye units.

203 modes, and exchange of energy; (iv) solvent caging of reactants and products; and (v) structural cha

204 with respect to weak perturbations, such as cage or solvent effects, remote chemical substituents, i

205 iet and further divided by housing in static cages or cages with running wheels for 2 weeks prior to

206 clude various types of architectures: finite cages or shells, essentially unbounded two-dimensional a

207 the opening of some of the small (sodalite) cages, otherwise inaccessible to most molecules.

208 350 nm irradiation of a cyclopropenone caged oxo-dibenzocyclooctyne (photo-ODIBO) biotin yields

209 ation efficiencies (FcP) of geminate radical cage pairs to the properties of the solvent.

210 A spiropyran-decorated covalent organic cage (PC2) has been designed, employing dynamic imine ch

211 The formation of the mixed-ligand cage [Pd2(tripy)2(2A-tripy)2](4+) was confirmed using (1

212 Rearing animals in open-exchange cages permits the release of organic wastes, some of whi

213 c force decay upon release of phosphate from caged phosphate was previously interpreted as a signatur

214 We report star polymer metal-organic cage (polyMOC) materials whose structures, mechanical pr

215 own anti-Plasmodium immune genes in a mixed-cage population with wild-type mosquitoes.

216 ad of the genetic modification in a mosquito cage population.

217 We allocated 48 caged populations initiated with homozygous GA and WT ad

218 ction of activated O atom within the solvent cage prior to escape into the bulk solution.

219 hat mediates C-N bond formation in an out-of-cage process.

220 formation via an alkyl radical in an out-of-cage process.

221 We foresee such DNA cage-protein complexes as new tools to study the role of

222 tions of the guest binding properties of the cages provided insights into the structural factors impo

223 diameters that are composed of multiple sub-cages providing numerous distinctive binding sites throu

224 The cage recognition properties over a variety of structural

225 teins can be enclosed in a deposited silica "cage", rendering them stable against denaturing thermal

226 The rattling of guest atoms in the large cages results in a very low thermal conductivity, a uniq

227 st bioadhesion, were internally labeled with caged rhodamine to make the particles photoactivatable.

228 ading to unprecedented "doughnut-shaped" DNA cage-ring structures.

229 comitant high- to low-spin transition of the cage's Fe(II) centers.

230 he assembled transcripts result validated by CAGE-seq.

231 of gas adsorption in a porous crystal whose cages share a common ligand that can adopt two distinct

232 The EPR spectrum of the singly reduced cage shows that the electron is localized on a single ND

233 This probe is the first example of a "caged" Si-rhodamine, exhibits higher photon counts compa

234 inside the nanocage increase with decreasing cage size.

235 60, in doped fullerenes, the breaking of the cage spherical symmetry makes super atomic molecular orb

236 ddends, and (iv) the variations in fullerene cage stability with the progressive addition of chemical

237 corporates the effects of pi delocalization, cage strain, and steric hindrance.

238 The 3D interconnected graphene cage structure leads to high capacity, good rate capabil

239 y transmission electron microscopy, adopts a cage structure similar to the pKM101 OMCC.

240 ullerene based on a simple evaluation of the cage structure.

241 The cage structures and UV/Vis spectra were independently co

242 competitive edge of ES over EG in population cages suggests that in a more heterogeneous environment

243 formation of a triiron cluster on the inner cage surface of each subunit.

244 ar binding of hydroxide ions to sites on the cage surface, both of which were established by competit

245 ons, are akin to those of rattling guests in caged-systems.

246 two double cavity polypyridyl [Pd3(L)4](6+) cages that bind cisplatin [Pt(NH3)2Cl2] within their int

247 o distinct BODIPY moieties, as well as mixed cages that contain both BODIPY chromophores.

248 ing the design of a system consisting of two cages that could release their guests in response to com

249 modular de novo design of polyhedral protein cages that efficiently self-assemble in vitro and in viv

250 amolecular molecules are hollow coordination cages that provide cavities of molecular dimensions prom

251 uch reader proteins bind Kme3 in an aromatic cage, the driving force for binding may differ; some rea

252 In both cages, the four covalent linkers that bind the two porph

253 gement that caught the hydrophobic core in a cage, thereby protecting it fully from aggregation in wa

254 t time, uniform and pinhole-free microporous cage thin films are formed and demonstrated as molecular

255 a method to transfer DNA patterns from a DNA cage to a polymeric nanoparticle encapsulated inside the

256 ts from the Human Epigenome Atlas and FANTOM CAGE to demonstrate its wide applicability.

257 ACh and choline differently in the aromatic cage to generate the different affinities.

258 anocube can modulate the affinity of the DNA cage to HSA.

259 ficial functional receptors, macrocyles, and cages to catalytically active metal complexes and helix

260 strategy to a new family of tubular covalent cages to create both 1D porous nanotubes and 3D diamondo

261 bination of treatment and control plots, and cages to exclude vertebrates, we made food resources ava

262 apes, among others, are transcribed from DNA cages to liposomes with high fidelity, giving rise to me

263 ate the selective phase transfer of cationic cages to separate a mixture of two cages and their respe

264 f 35 D. birchii families transplanted in 591 cages to sites along two altitudinal gradients, to deter

265 architectures, ranging from self-assembling cages to viral capsids.

266 d anion exchange, from 1[BF4] to 1[SO4], the cage, together with its encapsulated guest, can then be

267 However, most caged transmitters are, surprisingly, severe antagonists

268 In laboratory cage trials in which both species were exposed to insect

269 locomotor activity chamber (Paired) or home cage (Unpaired).

270 The atoms remain in the cages upon heating to 400 K.

271 r interaction with the surrounding inorganic cage using a combination of solid state nuclear magnetic

272 ime scale molecular motions of the molecular cages using ab initio molecular dynamics (AIMD) and clas

273 Ultimately, this "cage-walking" process provides a unique pathway to prefe

274 first observed Pd-catalyzed isomerization ("cage-walking") of B(9)-bromo-meta-carborane during Pd-ca

275 A series of aromatic-paneled Fe(II)4L6 cages was synthesized through iron(II)-templated subcomp

276 These cages were characterized by NMR and HRMS, and for cage 3

277 The ligands and cages were characterized by NMR spectroscopy, mass spect

278 The new cages were characterized by synchrotron X-ray crystallog

279 The new cages were characterized using X-ray crystallography, NM

280 ber of imine bonds formed, the corresponding cages were obtained in exceptionally high yields.

281 When two of these cages were present in solution together, one of them was

282 d behavior deficits including decreased home-cage wheel running and increased immobility in both tail

283 es LacI in a cage, but LacI can move between cages when hindering DNA strands move out of the way.

284 ven formation of quantized aggregates of DNA cages, where polymer length determines the cage aggregat

285 or LambdaLambdaLambdaLambda) Eu tetrahedral cages whereas the two other ligands, with two different

286 hese supramolecular keplerates as a class of cages whose composition and topological aspects compare

287 A 3D graphene cage with a thin layer of electrodeposited nickel phosph

288 ycloaddition of the anthracene panels of the cage with tetracyanoethylene (TCNE).

289 onstrated by the recent discovery of a Pt8L4 cage with unusual gyrobifastigium-like geometry.

290 nthetic modifications afforded three organic cages with alkynyl, alkenyl, and alkyl edges, respective

291 c ligands were more stable in water, whereas cages with ditopic ligands disassembled.

292 Here we report the synthesis of coordination cages with exceptional cross-sectional diameters that ar

293 design strategy to obtain regular synthetic cages with full control over their surface properties.

294 Cages with large, offset aromatic panels were observed t

295 studied and compared to those of two related cages with longer flexible linkers.

296 Despite this, when held in in situ cages with predators, those larvae that previously favor

297 Here we report porous molecular cages with proton conductivities (up to 10(-3) S cm(-1)

298 urther divided by housing in static cages or cages with running wheels for 2 weeks prior to breeding

299 us promises rapid access to covalent organic cages with well-defined architectures to study charge ac

300 were observed at later ages (when mice were caged without access to running wheels).