ライフサイエンスコーパス: calcineurin phosphatase

1 These actions require activation of calcineurin phosphatase.

2 of the Ca2+/calmodulin-dependent phosphatase calcineurin (phosphatase 2B) increases the frequency, bu

3 OS generation also blocked TGF-beta-mediated calcineurin phosphatase activity and decreased ECM accum

4 Foxo1 or Foxo3 in cardiomyocytes attenuates calcineurin phosphatase activity and inhibits agonist-in

5 t with these results, Foxo proteins decrease calcineurin phosphatase activity and repress both basal

6 peripheral lymphocytes, but their effects on calcineurin phosphatase activity are unknown.

7 rom steroid receptors mediate an increase in calcineurin phosphatase activity by steroid hormones.

8 is therefore concluded that AngII stimulates calcineurin phosphatase activity in proximal tubule epit

9 that were sufficient to inhibit 90% of total calcineurin phosphatase activity in the hypertrophied my

10 of a variety of oxidants and antioxidants on calcineurin phosphatase activity in vitro.

11 gulated kinase (ERK) kinase activity but not calcineurin phosphatase activity is required for LPS-sti

12 lcineurin-NFAT interaction without affecting calcineurin phosphatase activity may be useful as therap

13 Calcineurin phosphatase activity of cyclophilin-trialysi

14 Calcineurin phosphatase activity regulates the nuclear l

15 Calcineurin phosphatase activity was depressed similarly

16 Similar to NFAT, endogenous calcineurin phosphatase activity was increased in Jurkat

17 Calcineurin phosphatase activity was measured in permeab

18 promoter, up-regulated RCAN1 mRNA, inhibited calcineurin phosphatase activity, and exerted a striking

19 posed to cyclosporin A (CsA), which inhibits calcineurin phosphatase activity, failed to develop norm

20 ation at nanomolar potency without impairing calcineurin phosphatase activity, nuclear factor-kappaB

21 ET-1 stimulated calcineurin phosphatase activity, resulting in new prote

22 ease from intracellular stores and increased calcineurin phosphatase activity, resulting in NFATc1 nu

23 endent on the transcription factor Stat4 and calcineurin phosphatase activity.

24 the requirement for, and the dependence on, calcineurin phosphatase activity.

25 or their ability to maintain IM and to alter calcineurin phosphatase activity.

26 alytic subunit of calcineurin and inhibiting calcineurin phosphatase activity.

27 the rundown of IM and its ability to inhibit calcineurin phosphatase activity.

28 A calcineurin phosphatase antagonizes the KIN-29/MEF-2-reg

29 We demonstrate that Ca(2+)-activated calcineurin phosphatase binds to and promotes nuclear lo

30 ly ablate the main regulatory subunit of the calcineurin phosphatase complex in B cells to reveal bot

31 sely, a mutant with constitutively activated calcineurin phosphatase demonstrated decreased azole sen

32 el TRPC1 and involves Ca2+ signaling through calcineurin phosphatase for SSH activation and growth co

33 uch as cyclosporine A (CsA), an inhibitor of calcineurin phosphatase, frequently develop similar meta

34 Inhibition of calcineurin phosphatase has been shown to stimulate tran

35 x nuclear translocation was regulated by the calcineurin phosphatase in DP thymocytes.

36 Aquaporin 2 (AQP2), a putative substrate of calcineurin phosphatase in the kidney, is also involved

37 Recently, calcineurin phosphatase inhibition by cyclosporine or ta

38 The calcineurin phosphatase inhibitor cyclosporine A, which

39 bilization, and pretreatment of cells with a calcineurin phosphatase inhibitor prevented the spontane

40 -IgM-induced cell death in B104 cells by the calcineurin phosphatase inhibitor, cyclosporin A, abroga

41 The data suggest that calcineurin phosphatase inhibitors and prednisone can be

42 odels of chronic rejection, its synergy with calcineurin phosphatase inhibitors, and its inhibitory e

43 lls and inhibited by cell treatment with the calcineurin phosphatase inhibitors, cyclosporine (CsA) a

44 encodes a transcription factor regulated by calcineurin phosphatase; its disruption enhanced azole s

45 ce with a beta-cell-specific deletion of the calcineurin phosphatase regulatory subunit, calcineurin

46 CK2 and the calcineurin phosphatase TAX-6 modulate male mating behav

47 in 1 (RCAN1), an endogenous inhibitor of the calcineurin phosphatase that is triplicated in Down synd

48 calcium signals is largely mediated through calcineurin phosphatase, the inhibition of IL-12 product

49 es dephosphorylation by the calcium-mediated calcineurin phosphatase to promote NFAT nuclear accumula

50 alcineurin-interacting protein that inhibits calcineurin phosphatase when overexpressed, often upregu