ライフサイエンスコーパス: calcium buffer

1 ium buffer, but is randomly oriented in high calcium buffer.

2 m that is sensitive to the level of internal calcium buffer.

3 e the concentration of the mobile endogenous calcium buffer.

4 ers representing fixed and mobile endogenous calcium buffers.

5 f EF-hand proteins as calcium sensors versus calcium buffers.

6 i) decline using rate constants for cellular calcium buffers.

7 ighly sensitive to the amount of cytoplasmic calcium buffering.

8 ange is countered by increased intracellular calcium buffering.

9 e depends on mNCE activity and mitochondrial calcium buffering.

10 cell that have a high demand for ATP and/or calcium buffering.

11 are affected by dysfunction of mitochondrial calcium buffering.

12 espiratory dysfunction as well as diminished calcium buffering.

13 oupled with temporally precise intracellular calcium buffering.

14 signals by a mechanism independent of simple calcium buffering.

15 prestimulation and blocked by intracellular calcium buffering.

16 hanges in APD75 are altered by intracellular calcium buffering.

17 s revealed that, in the absence of exogenous calcium buffers, a single action potential evokes transi

18 ady-state intracellular calcium and enhanced calcium-buffering ability.

19 efense responses triggered by its C-terminal calcium-buffering activity in response to pathogen invas

20 28k is unique in that it functions as both a calcium buffer and a sensor protein.

21 nsport, functioning both as an intracellular calcium buffer and as a shuttle.

22 ransducer current at physiological levels of calcium buffer and external Ca2+ suggest that transducer

23 Control experiments with a non-calcium buffer and with domain mutants confirm that the

24 ent anion channels in mitochondrial synaptic calcium buffering and in hippocampal synaptic plasticity

25 oxygen species (ROS) generation, as well as calcium buffering and protease activation.

26 es to the cell, including energy production, calcium buffering and regulation of apoptosis.

27 SR calcium pump kinetics as well as intra-SR calcium buffering and SR calcium leak.

28 y an intracellular solution lacking any fast calcium buffer, and was restored by the addition of 1.2

29 ynaptic introduction of "fast" high-affinity calcium buffers, and the decay of facilitation was accel

30 r enzymatic digestion, to fast intracellular calcium buffers, and to intracellular pressure.

31 forated-patch recordings gave the endogenous calcium buffer as equivalent to 0.21 mM BAPTA in low-fre

32 The calcium buffer BAPTA attenuated the voltage effects of A

33 ization was abolished by the addition of the calcium buffers BAPTA and EGTA and could be induced by m

34 of calbindin-D(28k) may result not only from calcium buffering but also from the ability of the prote

35 osition of active microtubule sliding in low calcium buffer, but is randomly oriented in high calcium

36 Increasing the levels of nuclear calcium buffers by means of expression of a nuclearly ta

37 o be efficiently controlled by a native fast calcium buffer, calbindin-D28k, maintaining a lower vesi

38 drial transport in axon are increased axonal calcium buffer capability, diminished reactive oxygen sp

39 T mitochondria exhibit reduced mitochondrial calcium buffering capacity and are highly sensitive to m

40 Additionally, they have an increased calcium buffering capacity and generate fewer mitochondr

41 sults establish a close link between nuclear calcium buffering capacity and the transcription of gene

42 aling using CaMBP4 or increasing the nuclear calcium buffering capacity by means of expression of a n

43 st-mortem human brain that suggested loss of calcium buffering capacity in neurons correlated with ar

44 Here we show that the calcium buffering capacity of the cell nucleus in mouse

45 radicals and that it increases mitochondrial calcium-buffering capacity.

46 Intra-SR calcium buffering characteristics were also deduced.

47 he range of 2-5 sec) was observed under weak calcium buffering conditions.

48 nt was 77 +/- 3 (n = 14), and the endogenous calcium buffering constant component is likely to be bet

49 The average cytosolic calcium buffering constant was 77 +/- 3 (n = 14), and th

50 ain whether parvalbumin (Parv), a myoplasmic calcium buffer, could correct the diastolic dysfunction

51 her reports of genetic disruption of EF-hand calcium buffers, deletion of oncomodulin (Ocm), which is

52 s, and were uncoupled from each other by the calcium buffer EGTA.

53 human eyes from 17 patients were fixed in 5% calcium-buffered formalin.

54 e, we estimated that the dominant endogenous calcium buffer in dendrites is relatively immobile (diff

55 The major calcium buffer in these cells, calbindin D28K, is presen

56 have investigated the role of mitochondrial calcium buffering in excitotoxic cell death.

57 two orders of magnitude in the efficiency of calcium buffering in the cytosol and the ER lumen.

58 sm of the InsP3-receptor, InsP3 degradation, calcium buffering in the cytosol, and refilling of the E

59 These results demonstrate conclusively that calcium buffering in the mitochondrial matrix in live ce

60 onal role to immobile or fixed intracellular calcium buffers in central neurons because the amount of

61 Finally, the endogenous calcium buffers in spines remain unknown.

62 aptation to compare the effects of exogenous calcium buffers in the patch electrode solution with tho

63 mate transmission, mitochondrial fusion, and calcium buffering, is complex and was differentially reg

64 that persistent alterations in intracellular calcium buffering may be associated with opiate toleranc

65 In the inner ear, EF-hand calcium buffers may play a significant role in hair cell

66 e the effects that two commonly used "caged" calcium buffers (NP-EGTA and nitr-5) have on the amplitu

67 The effects of intracellular calcium buffering on electrical tuning were studied in h

68 The impact of calcium buffering on the initiation and propagation of m

69 In the presence of a nominal calcium buffer or EGTA, amphotericin B-induced IL-1beta

70 d mice can be partially rescued by improving calcium buffering, or decreasing action potential-evoked

71 Mitochondrial calcium buffering plays a major role after this type of

72 Back-extrapolation of the increases in calcium buffering power allowed us to calculate the calc

73 three experiments we modelled the additional calcium buffering power produced by multiple pressure in

74 The calcium buffering power, binding capacity and non-linear

75 Similarly, inhibition of the RyR and a calcium buffer prevented induction of priming by PKCepsi

76 Overexpression of calreticulin, a calcium buffer protein, blocked p12(I)-mediated NFAT act

77 ed the location, neurotransmitter phenotype, calcium-buffering protein expression, and axon distribut

78 ventral interneurons identified according to calcium-buffering protein expression, two groups (1 and

79 oviral gene transfer of parvalbumin, a small calcium-buffering protein found exclusively in skeletal

80 We expressed vertebrate calcium-buffer proteins in groups of cells in the networ

81 o, as evidenced by immunostaining intensity, calcium-buffering proteins were significantly elevated i

82 tion of the stimulus and sensitivity to slow calcium buffers reported for asynchronous release.

83 tribution to localized energy production and calcium buffering requirements.

84 r unique architecture and special energy and calcium-buffering requirements at the synapse.

85 Exogenous calcium buffers slow endocytosis but have no additional

86 oncentration with important implications for calcium buffering, synaptic plasticity, and protein-memb

87 , driven most significantly by the cytosolic calcium buffering system and changes in diastolic Ca(2+)

88 such as parvalbumin are part of the cellular calcium buffering system that determines intracellular c

89 r muscarinic cholinergic receptors or by low calcium buffer, tetrodotoxin or vesamicol.

90 has heretofore been considered a diffusible calcium buffer that is dispersed uniformly throughout th

91 cilitation mechanism involving an endogenous calcium buffer that is more efficiently saturated with l

92 e find that there is a time lag equal to the calcium buffering time constant between the instantaneou

93 ndicate, and (iii) is confined by endogenous calcium buffers to local dendritic regions even when syn

94 tration, can serve as a diffusionally mobile calcium buffer/transporter capable of regulating calcium

95 oltages and under conditions of low and high calcium buffering: tripling contrast reduced gain by app

96 nofluorescence in phagolysosome membranes in calcium-buffered vs. control macrophages.

97 Increasing intraterminal calcium buffering with EGTA-AM or decreasing calcium inf

98 Calsequestrin (CSQ) is the primary calcium buffer within the sarcoplasmic reticulum (SR) of